ライフサイエンスコーパス: two

1 each time the solution is passed between the two.

2 the Zn(2+) transport activity of HsZnT8; and two adjacent sites buried in the cytosolic domain and ch

3 s alpha-pinene, beta-pinene and camphene, or two alkene moieties like limonene, valencene, and beta-c

4 The surface film on pure magnesium and two aluminium-containing magnesium alloys was characteri

5 or brain MRI approached overall top one, top two, and top three differential diagnoses accuracy of ne

6 cytochrome c synthetases (CcmF and SirE) and two apocytochrome c chaperones (CcmI and SirG).

7 We show two applications using Primo to examine the molecular me

8 solidation or inducing memory extinction are two approaches for weakening maladaptive memories in dis

9 gned an open-label, randomized, multicenter, two-arm phase II trial to investigate cisplatin and gemc

10 lung mechanical properties underlying these two asthma phenotypes and the mechanisms explaining the

11 e inactivation of three-human adenovirus and two bacteriophages-MS2 and phiX174-in surface waters and

12 We tested our proposed approach over two benchmark datasets.

13 H, incoming nucleophiles displace one of the two bent bonds of bicyclic oxocarbenium ion intermediate

14 tide) (PEG-PDLLA) block copolymers, with the two blocks connected via a pH sensitive imine bond, we g

15 ation model which closes the gap between the two bounds and returns the optimal partitioning of verti

16 ic DNA templates and validated with DNA from two breast cancer cell-lines and two patient tumour tiss

17 Two candidate modules featuring voltage-dependent Ca2+-c

18 quantum chemical analysis, suggest that the two carbon atoms of the L->C(2) complex both have carben

19 Forty-two cats survived to discharge and 6 died or were euthan

20 In this retrospective, two-center study, we included two groups of inpatients w

21 We test two central tenets of the biotic interactions hypothesis

22 sures that centriole number is maintained at two centrioles per G1 cell.

23 m bladders vary from simple carrot-shaped to two-chambered to possessing various diverticula.

24 one, two, or even three antibiotics against two clinically isolated multi-drug-resistant bacteria st

25 sampled reef fishes at two outlet sites and two close reference sites, as well as four reference sit

26 hotosensitivity and photoreactivity of these two closely related photoreceptors.

27 s from 185 young women (average age 21.2) in two cohorts and tested the effects of OC on plasma level

28 Marine bacteria transform DMSP via two competing pathways with considerably different bioge

29 A two-component system CpxRA directly senses acidification

30 structural, and mechanical properties of the two components and are useful for applications that rang

31 by electropolymerization in the presence of two computationally selected and cysteine modified epito

32 For those with two conditions in addition to T2D, cardiovascular diseas

33 e, participants associated pairs of faces in two conditions: a famous, highly familiar face with a no

34 ation rate (eGFR) 59 to 30 mL/min/1.73 m2 on two consecutive previous blood tests were recruited from

35 build-up of Antarctic glaciation occurred in two consecutive stages across the Eocene-Oligocene trans

36 ichment and classification methods, offering two contributions.

37 We also demonstrate that two copies of the catalytic module of poly(A) polymerase

38 signaling must be controlled harmoniously by two counteracted teams including (1) auxin/indole-3-acet

39 Here we present two cryo-electron microscopy structures of human PAC in

40 Here, we report two cryo-EM structures of the intact V-ATPase from bovin

41 , and this percentage increased to 60% after two cycles of blinatumomab; the percentage of patients w

42 tructural and affinity analyses, we designed two cyclic peptide mimics of the TAR-binding beta2-beta3

43 S. oneidensis MR-1 encodes two cytochrome c synthetases (CcmF and SirE) and two apo

44 ected from multiple locations in the school, two days per week, throughout an eight-week sampling per

45 of carbonyl compounds emerged over the last two decades as a straightforward method for the formatio

46 Within two decades, research on NIRF nanoprobes has translated

47 aging methods of the nanoscale over the past two decades.

48 hat either survived or died over a period of two decades.

49 the records of patients who had a minimum of two dental exams at least 12 months apart at a single Un

50 Two detection zones each with shared reference and count

51 Under dilute reduction conditions two diastereomers of a borirane-borane intermediate are

52 xchange of both dialdehydes and triamines of two different [2 + 3] imine cages with the aid of a deut

53 e two sites were bound to miRNAs loaded into two different AGO paralogs, AGO1 and AGO2.

54 u-XANES identified titanium in predominantly two different chemistries, including metallic and titani

55 ing was retained when the two sites were for two different miRNAs or when the two sites were bound to

56 We report that, unexpectedly, in two different mouse xenograft models and four human and

57 sulfide bridges that locked the cassettes in two different relative orientations had opposite effects

58 Two different representative samples of children aged 6-

59 ranscription modulate the division timing of two different specialized cell types in the root stem ce

60 tion of supported phospholipid bilayers with two different types of membrane proteins, CorA and tissu

61 n sub-diffraction (SPEED) microscopy and its two-dimensional (2D)-to-3D transformation algorithm to p

62 movement of finger groups and in an offline two-dimensional cursor-control task, the SBP performed e

63 n of cellular membranes and, more generally, two-dimensional fluids on curved substrates.

64 of three embedded spirals for the case of a two-dimensional hexagonal lattice.

65 erate a concise feature map in the form of a two-dimensional image by minimizing the pairwise distanc

66 Here, we incorporate rather thick two-dimensional layered semiconducting crystals for reli

67 ation has been a key to provide high-quality two-dimensional materials, but despite improvements it i

68 and function for aluminosilicate zeolite MFI two-dimensional nanosheets before and after superheated

69 This procedure reduces the two-dimensional numerical search for the maximum of the

70 udy them comparing the living and non-living two-dimensional systems self-organizing at the spherical

71 These two dimensions of dietary diversity suggest contrasting

72 Here, we analyse two Dirac fermion species in two spatial dimensions in t

73 We also identified two distal quinone-binding sites with bound quinones.

74 e preceding BM fibril deposition, indicating two distinct but interdependent functions.

75 ize the structure of this carotenoprotein in two distinct oligomeric states.

76 st-induced signaling in this system involves two distinct receptor-G protein complexes, a conventiona

77 ulatory domain (CTD); a carotenoid spans the two domains.

78 ently originate from within the archaea in a two-domains tree when due consideration is given to the

79 descending groups, randomized 2:1 to receive two doses of TAK-003 or placebo 90 days apart.

80 Eighty-two Dutch patients with SCA3/MJD were evaluated annually

81 reactions due to the fact that in such cases two electrons from the coordinated amide are required to

82 aemia only, generating confusion between the two entities.

83 Changes in coordination between these two essential organelles are associated with metabolic d

84 the response of tumour spheroids formed from two established human cancer cell lines (HCT116 and CAL2

85 n as KDM6A) and activation of the RTK FGFR3, two events that commonly cooccur in muscle invasive blad

86 emonstrate translational read-through across two evolutionarily conserved, in-frame stop codons of MT

87 Two experienced surgeons performed vitrectomies at the G

88 contrast response functions were measured in two experiments with different tasks to control for atte

89 VH in group I. late recurrent VH occurred in two eyes (11.8%) in group II, IVA was given with complet

90 p = 0.01] and Actinobacteria [p = 0.02]) and two families (Moraxellaceae [p < 0.001] and Pseudomonada

91 s the mutant behaves differently between the two families of papillomaviruses.

92 We examined crowding for motion and color, two features that allow a strong test of feature indepen

93 ion, pressure-based approach to describe how two fishes, bluegill sunfish (Lepomis macrochirus Rafine

94 Yet, even with the current FDA approval for two FLT3 inhibitors, these modalities were unable to cur

95 A two-fold decrease in dilutions of PZA MIC for PZA suscep

96 apical shift of the gingival margin (almost two-fold).

97 Our aims are two-fold: (i) to inspire readers by further elucidating

98 How these two forcings affect the seasonal intensity and character

99 integration (the target capture complex) and two forms of the RAG strand transfer complex that differ

100 d self-cleavage is constitutive and produces two-fragment holoreceptors that remain bound at the cell

101 To address this question, we conducted two functional MRI experiments in which we dissociated t

102 In conclusion, MOCS1 produces two functional proteins, MOCS1A and MOCS1B, which follow

103 ance had strong, negative relationships with two gastropod predators-the Caribbean spiny lobster (Pan

104 We tested the efficacy of APTi with two gene families, the actin-dependent motor, myosin XI

105 rrelated with acylsugar accumulation, except two genes previously reported to be involved in acylgluc

106 In our model, mice clustered in two groups displaying high or low clinical scores.

107 The two groups had similar FLD at baseline; it progressively

108 retrospective, two-center study, we included two groups of inpatients with severe COVID-19 who had be

109 The radicals are divided into two groups of isomers, named open (O-) and closed (C-),

110 We injected two groups with shPKCdelta or shCtrl(PKCdelta) into CeL

111 and level of disability, were similar in the two groups.

112 r systemic adverse events was similar in the two groups.

113 These two GTPases can be observed to interact transiently on m

114 reomeric transition states stemming from the two half-chair conformations of their lithium chelate.

115 After two heart attacks in three years, an associate professor

116 inding beta2-beta3 loop sequences present in two high-affinity TBPs (K(D) values of 4.2 +/- 0.3 and 3

117 we found that when expressed in human cells, two highly homologous HSP70s, HSPA1A and HSPA1L, have op

118 Two home-built instruments were utilized, featuring cohe

119 were retrospectively identified in women at two hospitals (a large tertiary care academic hospital a

120 Two hundred nine FSPs were selected and cloned into nonh

121 Two-hundred five unrelated probands with various forms o

122 Affinity purification and pairwise yeast two-hybrid analysis suggest that ZC3H5 forms a complex w

123 interactions were not previously detected by two-hybrid or AP-MS techniques.

124 Two hypotheses were tested for the genetic diversity of

125 Two ICU physicians independently reviewed progress and c

126 ART after 2.3 months of age, one of whom had two identical intact sequences, suggestive of a cell clo

127 f oncology therapeutics, with eight ADCs and two immunotoxins approved for clinical use.

128 (Arabidopsis thaliana) AtSCS gene results in two in-frame transcripts and subsequently two proteins,

129 25, N = 60) from the same individuals and in two independent brain collections (BA10, N = 81 and 64).

130 e, cell layer capacitance and TEER represent two independent properties characterizing the monolayer.

131 This association was replicated in two independent samples of SJLIFE survivors of European

132 l microbiome to influence host physiology in two Indigenous communities in the Torres Strait Islands:

133 monomer forms a compact structure comprising two intercalated rings of C-type lectin-like domains, wh

134 ocampal theta thus supports learning through two interleaved processes: strengthening encoding of nov

135 We found that the ORS is composed of two intermingling but transcriptionally distinct cell ty

136 irregular fluctuation of perception between two interpretations of a stimulus-occurs when observing

137 7 act as molecular tethers, inter-connecting two intracellular compartments to enable efficient trans

138 It is characterized by two invariant histidine residues that play a critical ro

139 Two investigators independently rated study quality.

140 nsure optimum execution of the stages across two invocations of the pipeline.

141 We reveal a gating mechanism that involves two ion-conducting pathways.

142 shows a differential expression pattern for two isoforms of 36 and 33 kDa.

143 we designed and synthesized molecules where two isomeric, yet, different, 8pai antiaromatic subunits

144 acidity influencing isoprene-derived SOA in two isoprene-rich forested environments representing cle

145 gical analysis on muscle biopsies, while our two late DUX4 target gene expression biomarkers associat

146 The mantle source compositions of the two lava units change towards less radiogenic Nd, Hf, an

147 produced are compared with those produced by two leading hyperspectral visualization techniques in th

148 In contrast to an optical cavity, a two-level system operates with no more than a single ene

149 The model was constructed at two levels of granularity, using either biophysically de

150 ed or refractory DLBCL who received at least two lines of previous chemoimmunotherapy.

151 cromass biomarker amino sugars and SOC, from two long-term agricultural field studies conducted by la

152 preserved in convex hyporelief, and include two main morphological variants that reflect a behaviour

153 s4B dimerizes in silico and in vitro through two major interfaces: (i) beta-interface, mapped to Swit

154 Two major mechanism hypotheses, both involving ESAA reli

155 In precision oncology, two major strategies are being pursued for predicting cl

156 The two major types of reactions that are catalyzed by AOXs

157 rs, containing an azobenzene photoswitch and two malonate groups, in the double cyclopropanation of [

158 to cis-regulation in mouse ESCs, we assayed two massively parallel reporter assay (MPRA) libraries c

159 echanistic studies are presented that reveal two mechanisms for C-H borylation, (i) electrophilic aro

160 amic competition between the NRs governed by two mechanisms.

161 Thus, GLD may be caused by at least two mechanisms: psychosine-induced demyelination and sec

162 ctococcus lactis Protein production in these two microbial hosts was enhanced by codon optimization a

163 ndent on Mn(II) oxidation to a co-culture of two microbial species.

164 In DdPhyA, two mobile loops that enclose substrates in the PHDs are

165 ination mixture method, a method for MR with two modalities.

166 bitofrontal and anterior cingulate cortex of two monkeys performing a valuation task.

167 ilus LP vaginal tablet (L. rhamnosus 35) for two months.

168 inting to a similar distribution between the two muscles types and indicating no additional risk in t

169 also evaluated for the determination of the two mycotoxins in whole grain samples (wheat and maize).

170 logy and natural substance drugs included in two NCI drug libraries representing a variety of chemica

171 Finally, we found that these two neural states tended to fall at either end of a neur

172 chalcone, 2'-hydroxy-3-phenylpropionate, and two new compounds, namely (Z)-1,6-bis(2-hydroxyphenyl)-3

173 In this work, two new curvature-based angularity indices are introduce

174 These studies were supported by two NIH grants for 22 and 19 years, respectively, and a

175 proximation analysis taking into account the two-node correlation.

176 le-cell RNA sequencing, we here estimate the two noise components of 3975 genes in mouse fibroblast c

177 Among these, the combined use of two novel antigens and one previously described antigen

178 s, highly familiar face with a novel face or two novel faces while undergoing fMRI.

179 T Cel7A and several variants in which one or two of four highly conserved Trp residues in the binding

180 ile the pharmacological profiles of at least two of the generated ADCs compare well with the profiles

181 riety of different countries and cultures in two of the most commonly used designs in experimental ec

182 These findings highlight that two of the most pervasive global change drivers operate

183 summer heatwaves and poor water quality are two of the most prevalent and severe pressures faced by

184 We examined the structure of two of the novel orbitides by NMR, finding one had a def

185 Two of these cores are related to the spectral propertie

186 loids, but most studies have focused on just two of these, mitragynine and 7-hydroxymitragynine.

187 k or shoulder pain in the UK Biobank cohort, two of which were weakly supported in a replication coho

188 e that takes advantage of the combination of two oppositely oriented coaxial domes, providing an oppo

189 ese three positions, a number suggested that two or all three of these processes were central to the

190 s that are differentially correlated between two or more subsets of the data.

191 antimicrobial susceptibility tests with one, two, or even three antibiotics against two clinically is

192 Deferasirox and deferiprone are the only two oral chelators used in adult patients with transfusi

193 que switching of Cr(2) Ge(2) Te(6) are about two orders of magnitude lower than those required for sw

194 Two other E. coli proteins that contain SecA-like MBDs,

195 We injected two other groups with shSOM or shCtrl(SOM) into CeL and

196 the core MICOS subunit Mic60 in relation to two other MICOS proteins, Mic10 and Mic19.

197 high CO(2) -mediated response in tomato and two other Solanaceae crops is distinct from that in Arab

198 hypersaline brine, we sampled reef fishes at two outlet sites and two close reference sites, as well

199 inverted" ligand field, with an approximate "two-over-three" splitting of the d-orbitals and a high d

200 lear how distinct structural features of the two PA2G4 isoforms translate into different functional o

201 Expression of xbp-1s in just two pairs of neurons that synthesize tyramine, the RIM a

202 ent functions for KHARON, we have identified two partner proteins, KHAP1 and KHAP2, which associate w

203 tter and the thalamus, compared to the other two patient groups.

204 th DNA from two breast cancer cell-lines and two patient tumour tissue samples through a qPCR instrum

205 Fifty-two patients (48, three, and one with DSRCT, peritoneal

206 One hundred twenty-two patients from 7 medical centers in the United States

207 Three more FPGS mutants were identified in two patients, NT5C2 mutations in six patients, and PRPS1

208 ations in six patients, and PRPS1 mutants in two patients.

209 n = 14) generated from peripheral B cells of two patients.

210 Here we report the modification of two peptides that comprise a coiled-coil heterodimer pai

211 photoemission spectroscopies, bonding of the two peptides to TiO(2) surfaces (either nanostructured o

212 address this disconnect, inhibitors bearing two pharmacophores-a zinc binding group and a Cys-reacti

213 Here, we describe the two-phase process by which antigen drives the generation

214 explained by the genetic overlap between the two phenotypes and, hence, shared biological mechanisms.

215 of CD14(+)CD11c(+) macrophages from mucus in two phyla (Proteobacteria [p = 0.01] and Actinobacteria

216 principles of visuo-social processing across two phylogenetically distant mammal species.

217 forms, and we here present evidence that the two pools of Lck have different molecular properties.

218 University of Queensland, Gatton campus with two populations sourced from high (Gatton) and medium (S

219 Two-pore-domain potassium channels (K(2P)) are the major

220 These two possibilities were simulated in the different microw

221 tion as a solvent-separated ion triplet with two potassium counterions.

222 convey a high risk of recurrent stroke, but two previous trials (SAMMPRIS and VISSIT) did not show s

223 These results demonstrate the existence of two previously unidentified interactions: one between A3

224 However, superiority of IORAT over the other two procedures should be weighed against its significant

225 are responsible for a cross-talk between the two processes that buffers steady-state mRNA levels.

226 athology, in part, through the production of two proinflammatory cytokines: interleukin-17 (IL-17) an

227 We present the current evidence for the two proposed models of EET taxis, "electrokinesis" and f

228 in two in-frame transcripts and subsequently two proteins, that differ only by the sequence position

229 an inference with the longitudinal data from two published clinical studies.

230 RS)-based molecular sensors for detection of two putative fatty acid receptors, G protein-coupled rec

231 oice test about basic semiology and answered two questions evaluating their degree of confidence in i

232 This structure reveals that two Rab33B molecules bind to the diverging alpha-helices

233 Two radiologists classified each radiograph as adequate

234 rom multiple species of RKNs and showed that two RALF-likes (i.e., MiRALF1 and MiRALF3) from M. incog

235 Here, we connect these two reaction pathways using bases and a simple Pd-based

236 In this study, we combined two recent deep mutational scanning (DMS) datasets probi

237 Two recent papers in Cell Stem Cell (Zhu et al., 2020) a

238 d the transcriptome from multiple tissues of two recently diverged Ficedula flycatcher species and th

239 We have re-examined the roles of the two receptor populations using mice with picrotoxin resi

240 ry coding in the human hippocampus and mPFC, two regions that are important for memory-guided behavio

241 s accompanied by alpha coherence between the two regions.

242 w differences in tubulin populations between two related Xenopus frog species influence microtubule d

243 Two relevant CB7 effects are proposed, a base-catalyst m

244 Using a mouse model with two reporter genes, we observed that, while GHRH(tdTom)

245 iscrete reaction slug back and forth between two residence coils, with analysis performed each time t

246 sume a spiral conformation and interact with two-residue segments of substrate in the axial channel,

247 In contrast, we found two residues in the C-terminal domain, tyrosine 351 and

248 rrent-voltage curve, and substituting one or two residues in the selectivity filter drastically incre

249 lacetonate) with the support and anchored by two Rh-O bonds at framework tetrahedral sites, as shown

250 os of a metabolic feature calculated between two samples may not reflect their real metabolic concent

251 e findings were consistently observed in the two samples.

252 gans that processes information perceived by two sensory neurons to control the induction of hydrogen

253 erminate with an opening of the complex into two separate domains, one of which acts as a quencher fo

254 The methodology developed involves two sequential acid treatments followed by stepwise etha

255 lico analysis predicted the presence of only two short allergenic peptides on the surface of CpCP3, w

256 e-sided, symmetric two-sided, and asymmetric two-sided extrusion.

257 Theory indicates that symmetric two-sided loop extrusion can achieve such compaction, bu

258 condensins that perform one-sided, symmetric two-sided, and asymmetric two-sided extrusion.

259 es were for two different miRNAs or when the two sites were bound to miRNAs loaded into two different

260 Cooperative binding was retained when the two sites were for two different miRNAs or when the two

261 Switching between these two spatial coding modes was supported by the interactio

262 ere, we analyse two Dirac fermion species in two spatial dimensions in the presence of general quarti

263 Using a two-species experimental system of the flour beetles Tri

264 Here, we compared two splicing variants (V1, V2) of murine UHRF1 (mUHRF1)

265 ishes a clear path to the next generation of two-step VT complexes through incorporation of mixed-val

266 We also developed two structurally similar control compounds, 5 (MS167) an

267 levels of enantioselectivity, even when the two substituents are both primary alkyl groups.

268 positions suggesting distinct effects of the two substrates.

269 l constituents of Hyssopus officinalis L. in two successive harvests.

270 Two suggest that the initial clustering is due to nuclea

271 we compare and analyze the activity of these two superbases.

272 Two symptom-medication scores were used: the modified EA

273 l yields varying from 32 to 64% according to two synthetic pathways: (1) using a titanium-reductive a

274 and synthesis of 61 qualitative studies and two systematic reviews describing older patients' experi

275 rization of complex formation of a BsAb with two target antigens, cluster of differentiation 3 (CD3)

276 re important for memory-guided behaviors, in two tasks: one where attention was guided by memory and

277 benefit can extend to a large region because two thirds of patients treated at KHCC were non-Jordania

278 However, research suggests that up to two-thirds at risk to inherit LS don't participate.

279 ring cycle one, once every 3 weeks in cycles two through nine, and once every 4 weeks thereafter as m

280 eriole diameter relative to the awake state, two to five times larger than those evoked by sensory st

281 In Listeria monocytogenes, prophages encode two to three distinct anti-Cas9 proteins, with acrIIA1 a

282 anges and typically have short half-lives of two to three generations.

283 Globally, soils store two to three times as much carbon as currently resides i

284 Engaging two transition metal catalysts for this goal presents a

285 preferred integration of single spacers over two transposon ends.

286 1239-1251) show that two types of knobs, those composed of 180-bp and TR1 seq

287 High-resolution analyses of these two types of QTLs reveal distinct positions of enrichmen

288 Most bacteria utilize two types of synthases that polymerize glycan strands an

289 We define the structures of two unique species-specific components (Cag3 and CagM) a

290 Missense CASR variants were identified in two unrelated hypocalcemic individuals.

291 en the transcriptional responses elicited by two unrelated individual drugs are correlated.

292 A two-variable classifier yielded a cross-validated area u

293 For two variants that were predicted to be benign, in vitro

294 Two variants, DAD2(N242I) and DAD2(F135A), having substi

295 l load trajectory analyses (ie, had at least two viral loads in the year after end of pregnancy).

296 ase of adjuvants and antigen from days up to two weeks.

297 ctral properties and walks of length one and two which contain at least on hub node, and they are rel

298 ) at the arrest of fruit phloem unloading of two white grape Vitis vinifera cvs.

299 ents were reported with capsular release and two with manipulation.

300 Two-year therapy prevented a 1-month-of-life loss, and r