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1 rpenetrated (UWDM-2, three-fold, and UWDM-3, two-fold).
2 The purpose of the web server is two fold.
3 ellular adhesion molecule-1 (Icam1) by about two-fold.
4 ations and genomic correlations by more than two-fold.
5 showed HER-2 DNA amplification of more than two-fold.
6 reased prevalence of resistance by more than two-fold.
7 AXL in overexpressing cells reduced survival two-fold.
8 response to the proposed WHO convention was two-fold.
9 ed by two-fold, and PDL surface increased by two-fold.
10 The effect of ARF6 on tubule initiation is two-fold.
11 ting pair, were neurally amplified more than two-fold.
12 f beta-carotene accessibility was only about two-fold.
13 thaumatin variant increased by greater than two-fold.
14 The reason for this is two-fold.
15 The motivation of this study is two-fold.
16 The reasons are two-fold.
17 Our findings are two-fold.
19 The objectives of the current study were two-fold: 1) to describe the pattern of sleep disturbanc
20 veal that the mechanism for self-shedding is two-fold: (1) that the external force on condensate bulk
22 least 97% of sensitivity and could deliver a two-fold, 20-fold, and 6-fold increase in selectivity, r
23 baseline plasma total cortisol was elevated two-fold (463 nmol/L [284-742 nmol/L] vs 245 nmol/L [200
24 = .69), but underpredicted Asian carriers by two-fold (49 observed v 25 predicted by BRCAPRO; 26 pred
28 s that were differentially expressed by over two-fold and p < 0.05, of which 46 genes were upregulate
29 haplotype (GCA), which increased DMFT scores two-fold, and a low- caries-experience haplotype (ACG),
32 ulation increased proapoptotic regulator Bax two-fold at mRNA and protein levels, while antiapoptotic
34 and a transient non-catalytic pocket on the two-fold axis at the GyrA dimer interface, and is close
36 cale simulations and 3D printing is having a two-fold benefit: first, 3D printing can be used to vali
37 Anti-C2Cat recognizes active cPKCs at least two-fold better than inactive kinase in ELISA and immuno
39 istically differentially expressed by > or = two-fold between T4 treatments at one or more non-Day 0
41 t one-pot Cu-catalyzed C-H functionalization/two-fold C-N bond formation protocol for the syntheses o
42 fter ABT-737 treatment, this agent induces a two-fold change in the transcription of nearly 430 genes
43 rong predictor of overall survival (HR for a two-fold change of 1.23, 95% CI 1.13-1.34; p<0.0001) and
46 odds of successful dural culture was almost two-fold compared with scalp (OR = 1.95, 95% CI: [1.01,
48 tions obtained by computational modeling and two folded conformers that were proposed in a previous N
50 ntent of spikes, emphasizing that there is a two-fold cost of converting analogue to digital; informa
51 g equally in sons and daughters experience a two-fold cost relative to asexuals producing only daught
53 oupling products can be used in a subsequent two-fold cross-coupling to give trisubstituted imidazole
54 imidazole-1-yl)methanimine (6) followed by a two-fold cyclization, which resulted in guanidinium salt
55 ophil gelatinase-associated lipocalin; and a two-fold decrease in glycosylated clusterin (all p < 0.0
58 NA's "spring-like" conformation would give a two-fold decrease of stretch modulus relative to dsDNA.
59 did not result in enhanced surface levels of two folding-defective human V2-vasopressin receptor muta
60 ion was dysregulated (P<4.7E-07 and at least two-fold difference in magnitude) in cardia or noncardia
63 an dimer, these distance restraints all have two-fold directional ambiguity, and resolving such ambig
65 spectroscopy that the linker connecting the two folded domains is flexible, accommodating Lin28 bind
68 ternary catalyst shows much higher activity (two-fold enhancement at 0.5 V in fuel cells) than the st
70 ons, but this was accompanied by a more than two-fold enrichment in reciprocal FSI-PN connections.
71 d residue 19 from serine to alanine enhanced two-fold ERRalpha1's response to the coactivator GRIP-1.
74 e version were at significantly higher risk (two-fold) for disease progression (P for interaction = 0
75 r one or the other s10, and the ratio of the two folded forms, unambiguously distinguished by their r
76 out life-supporting treatment were more than two-fold greater among surgeons who felt it was acceptab
77 ythrocyte sedimentation rate (p=0.009) and a two-fold greater decrease in Z score of the left anterio
79 mber of new striatal cells was approximately two-fold greater in R6/2 vs. wild type mice, while SVZ c
80 ients treated with primary ADT had an almost two-fold greater likelihood of CVM (HR, 1.94; 95% CI, 1.
81 storage than premenopausal women, including two-fold greater meal FA storage in the femoral depot.
82 e mutations or truncating mutations each had two-fold greater odds of developing eye problems than th
85 etula, is the most dominant pollen exposure, two folds higher than to Poaceae, and greater than five
89 ty-three genes were identified with at least two-fold higher expression in wild type than aganglionic
90 ically, total N, NO(3) and NH(4) were nearly two-fold higher in soil underneath aspen dominated stand
91 ns of TNFR-1, TNFR-2, and KIM-1 were roughly two-fold higher in the advanced DKD population (NEPHRON-
93 3 to 4 drug-related adverse events more than two-fold higher in the sorafenib group included hand-foo
97 imes faster, were more perfused, exhibited a two-fold higher mitotic index, and were more highly posi
98 seline ACH loss severity, HT never-users had two-fold higher odds of being in the severe ACH loss cat
99 Exon 5-containing NMDA receptors also have a two-fold higher open probability (0.037) than exon 5-lac
100 state 13-acetate (TPA, 100 nM, 4 h), induced two-fold higher protein and mRNA levels of p21(Waf1), a
104 longitudinal epidemiological studies show a two-fold higher risk of cardiovascular disease (CVD) in
108 of prostate cancer in individuals with LS is two-fold higher than in the general population and is sl
109 o for rilpivirine in rectal tissue was about two-fold higher than in vaginal and cervical tissue (1.1
110 aCD against multispecies 2-day biofilms were two-fold higher than MICs of cells shed from biofilms.
111 56A distance between mannoses was four- and two-fold higher than NCs with 39A and 89A distances, res
112 % overall risk of mortality from CCA--nearly two-fold higher than that for MSCT angiography (0.07%).
113 e adjusted odds of dying in-hospital is over two-fold higher than the reference category and exceeds
114 rattleboro rats had a reduced urine flow and two-fold higher urine osmolality during the first 12 hou
118 ry postsynaptic currents (sEPSCs) three- and two-fold higher, respectively, than those of adapting ne
119 rs of 5 to 14 and 45+ cigarettes daily had a two-fold (HR, 1.94; 95% CI, 1.72, 2.18) and three-fold (
120 nge of ab initio FS detection is, therefore, two fold: (i) to find a way to infer necessary model par
122 h a 15 mm tissue phantom, our method shows a two fold improvement in spatial resolution (4db increase
125 detection limits of the electrode increased two-fold in contrast to the beta-CD-MWCNTs/GCE sensor.
126 Only ESR1 was downregulated by more than two-fold in ER-positive cancer events in the tamoxifen a
129 intestinal tumour epithelial cells by almost two-fold in primary culture of tumour cells from Apc(Min
131 that were differentially expressed by > or = two-fold in the 5 and 50 nM T4 treatments, respectively.
133 tly cation-selective channel increases about two-fold in the H2 PO4(-) <Cl(-) approximately Br(-) app
134 AKT activation was further increased by two-fold in TRbeta(PV/PV)Pten(+/-) mice thyroids, leadin
135 hat are differentially regulated by at least two-fold in watermelon fruits during the early, ripening
136 anisotropic response, which arises from the two-fold in-plane anisotropy of the complex refractive i
142 ed from non-dividing cells by a greater than two-fold increase in cell contrast, and we demonstrate t
144 l and phase-conjugated nanostructures showed two-fold increase in diffracted light intensity under mo
146 nt elongation of fiber structures as well as two-fold increase in GFAP-positive fibers as compared wi
147 ment dose was evaluated, there was an almost two-fold increase in lung cancer risk among men in the h
148 , non-transplanted, aged AD mice and found a two-fold increase in microglia compared with wt mice, pr
149 ng cold shock at 10 degrees , resulting in a two-fold increase in PNPase activity, compared with the
152 , they predicted a 40% increase in ROD and a two-fold increase in ROD if PSA-P occurred at 3 months.
153 ontal and anterior cingulate cortices, and a two-fold increase in Sig-1R protein expression in anteri
154 by flagellates from 0% to 100% results in a two-fold increase in SPPR estimates in the Barents Sea.
157 lative to the best-performing scenario and a two-fold increase in the abundance of adult vaquita over
162 ormation of glial ensheathment resulted in a two-fold increase in the discontinuities, indicating tha
163 mbrane potential of Lim2(Gt/Gt) lenses and a two-fold increase in the effective intracellular resisti
166 the in vitro migration assay demonstrated a two-fold increase in the migratory potential of HA-treat
167 patterns the ventral neural tube, produced a two-fold increase in the number of olig2(+) neurons.
168 ilitated approach resulted in a greater than two-fold increase in the number of patients with initial
169 EGF signaling was attenuated, we detected a two-fold increase in the percentage of GSCs in mitotic d
170 d vascular endothelial growth factor), and a two-fold increase in the proliferation rate in AURKA ove
171 tal carcinoma in situ) are associated with a two-fold increase in the risk of IBTR compared with nega
172 aprotinin was associated with a greater than two-fold increase in the risk of renal dysfunction after
175 of the checklist resulted in a greater than two-fold increase in transferring patients out of the in
176 mice have markedly reduced plasma HDL and a two-fold increase in triglyceride due to failure to asse
177 y changes in tumor vascular morphology and a two-fold increase in vascular density) was associated wi
180 chotomized, the hazard of mortality showed a two-fold increase when comparing women with less than 50
181 showed that 38 genes were highly expressed (two-fold increase) in all samples, while 41 genes were u
183 ho smoked more than 33 years had more than a two-fold increased risk of ALS compared with never smoke
184 tients treated with WW/AS had a greater than two-fold increased risk of CVM (HR, 2.46; 95% CI, 1.53 t
185 Current smokers at recruitment had an almost two-fold increased risk of dying from ALS compared to ne
186 first-degree relatives of patients exhibit a two-fold increased risk of glioma, the search for suscep
187 a five-fold increased risk of diabetes and a two-fold increased risk of heart disease when compared t
188 acetaminophen was associated with an almost two-fold increased risk of incident hematologic malignan
189 CV infection is temporally associated with a two-fold increased risk of lymphoid-neoplasms, especiall
191 studies have suggested a one and one-half to two-fold increased risk, especially immediately after in
192 hol dependence was associated with more than two-fold increased risk-adjusted odds of hospital mortal
194 (3-6) stability studies indicated more than two folds increment in half-life and enhanced tolerance
198 um triflate in facilitating this reaction is two-fold: it enables "ate" complex formation and overcom
199 med that reducing gene dose by half leads to two-fold less expression, there is partial autosomal dos
200 e plaque fecundity are longer (e.g. at least two-fold longer) than latent periods that optimize plaqu
201 Among ever-users of HRT, recurrence risk was two-fold lower for estrogen receptor (ER)--positive and
209 potential peroxidase activity was inhibited two-fold more than the hydrolase activity and was positi
210 erization enhances TOC1 nuclear accumulation two-fold, most likely through enhanced nuclear import.
214 proteins were consistently more abundant (by two-fold or greater) in ADPKD-uEVs than in healthy- and
217 the 2Cu2 core is structurally invariant upon two-fold oxidation, while XAS measurements at the Cu K-e
218 els [mean+/-SEM] were increased by more than two fold (P<0.001) in the diabetic patients (5.56+/-0.73
221 11-fold (P = .005), 15-fold (P < .001), and two-fold (P = .02), respectively, during adenomatous tra
222 increased reactive oxygen species by almost two-fold (p = .052), without affecting the NO level ther
223 re was a statistically significant increase (two-fold, P < 0.05) in oral neutrophil counts found in p
224 E- clones for at least one tissue (more than two-fold; P < 0.0001, 238 E+ > E- and 240 E- > E+), alth
227 -dependent vascular reactivity and induces a two-fold proliferation in skeletal muscle capillarity.
228 evaluate the potential of mean force between two folded protein molecules that allows for complete sa
229 mal individuals is responsible for roughly a two-fold range in platelet protein content, including ke
231 % in castrated men and was associated with a two-fold reduction in area under the curve (P = .0001),
232 cilia formation by serum starvation led to a two-fold reduction in ciliogenesis in fibroblasts derive
233 astic superhydrophobic surface can lead to a two-fold reduction in contact time compared to equivalen
234 hitefly-infested plants exhibited at least a two-fold reduction in gall formation on both stem and cr
235 rm, those with MPO G alleles had more than a two-fold reduction in hazard of recurrence (adjusted haz
240 iously unreported ionic interactions between two-fold-related trimers that build up the cubic core.
243 Overall, cancer survivors had more than two-fold risk of developing CVD (adjusted incidence rate
244 bind in an identical manner and with overall two-fold rotational symmetry, consistent with the palind
245 enhancement of apoptosis, and approximately two-fold sensitization to cisplatin and temozolomide.
246 lices from Lis1(+/-) mice, we noted a nearly two-fold significant increase in the frequency of sponta
247 eversibly switches from a highly anisotropic two-fold state to a more isotropic one, with concomitant
248 osome-excluding' poly(A)/poly(T) is at least two-fold stiffer than random-sequence dsDNA in bending,
250 scape of the protein is a triple funnel with two folded structures and one misfolded structure that a
251 efficiency of plasmid segregation (by about two-fold), suggesting that it might contribute to anchor
253 grees C by solid-state NMR, showing that the two-fold symmetric "agitated" (A) polymorph is more stab
255 ral features such as a horseshoe-like pseudo two-fold symmetric fold, several canonical sequence moti
256 H-PhnI-PhnJ; PhnGHIJ), and show that it is a two-fold symmetric hetero-octamer comprising an intertwi
257 ns a pair of active sites organized within a two-fold symmetric homodimer or pair of fused, homologou
262 inding domain reveals that Rab6 recognizes a two-fold symmetric surface on a coiled coil immediately
263 f Zn(II)-bound AdcR reveals a highly helical two-fold-symmetric dimer with two distinct metal-binding
264 lar interest, the micro-OR crystallizes as a two-fold symmetrical dimer through a four-helix bundle m
265 in all AAVs: depressions at each icosahedral two-fold symmetry axis and surrounding each five-fold ax
266 otide binding domains are misaligned along a two-fold symmetry axis, revealing a possible mechanism b
268 osition on the lanthanide, thus breaking the two-fold symmetry of the CLaNP tag in a pH-dependent way
269 A binding proteins generally make use of the two-fold symmetry of the double helix, zinc fingers can
270 like domain loops that lie in proximity with two-fold symmetry on the surface of the central rod.
271 The receptor harbours an overall axis of two-fold symmetry with the extracellular domains organiz
273 -molecular-weight oligomers with an apparent two-fold symmetry, which are efficient inhibitors of non
277 ansverse spin cone symmetry restricted to be two-fold, the one-step sharp magnetization reversal is r
279 r in AMPA, but not kainate, receptors with a two-fold to four-fold symmetry transition in the ligand-
280 e ranged from 15 mg to 60 mg, resulting in a two-fold to three fold gradient of mean trough drug expo
281 type 2 (HSV-2) infection is associated with two-fold to three-fold increased risk for HIV-1 infectio
282 hypothyroidism and HCC, with an approximate two-fold to three-fold increased risk of HCC development
284 The ultimate goals of the consortium are two-fold: to develop and implement strategies for in vit
286 rrent parameterization of TBMs resulted in a two-fold underestimation of the capacity for leaf-level
287 the microarray analysis, 35 and 31 more than two-fold up-regulated and down-regulated genes, respecti
289 ed and downregulated, respectively, at least two-fold upon Stau1 depletion in three independently per
290 glucocorticoid receptor-beta expression was two-fold upregulated (p<.01) and exhibited a remarkable
291 roglia and RGCs, suggesting an approximately two-fold upregulation in ocular hypertensive rat eyes an
293 in rates of agency indicators, but less than two-fold variation in violent deaths or maltreatment-rel
294 36 genes with expression values greater than two-fold were found to be modulated by light treatment.
296 H)-yl)methanone) enhances receptor responses two-fold with an EC(50) of 3 muM by increasing channel o
298 on of chromatids in CPCs is increased nearly two-fold with Pim-1 kinase overexpression, indicating th
299 ic liquids facilitated electron transport by two-fold without any interfacial barrier through carbon
300 er smokers was independently associated with two-fold worsening of DSS, DFS, and OS after surgery for
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