ライフサイエンスコーパス: twofold

1 he elongation rate of new edges by more than twofold.

2 cantly enriched in miR-200c binding at least twofold.

3 The purpose of the present letter is twofold.

4 eading exonuclease activity reduced fidelity twofold.

5 ated) adiponectin release level was elevated twofold.

6 ATEMENT The significance of this research is twofold.

7 ion by 38% and slowed amyloid propagation by twofold.

8 The significance of this study is twofold.

9 ppression of only 26 transcripts by at least twofold.

10 tly after birth; heart size increases almost twofold.

11 rides further improved ferritin formation by twofold.

12 iously studied; however, the effect was only twofold.

13 rving such interactions for two electrons is twofold.

14 Our goal was twofold.

15 tional human insulin gene-enhanced secretion twofold.

16 lies, expression of X-linked genes increases twofold.

17 ion experiment and a computer simulation, is twofold.

18 pression in transient transfection assays by twofold.

19 oncentration in CRPs increases approximately twofold.

20 Our results were twofold.

21 ty by 99-fold and increasing Mg(2+) affinity twofold.

22 The goals of this work are twofold: 1) to categorize secretion features that deviat

23 The aim of this research is twofold: 1) to shed light on zika's binding and entry me

24 The aim of the current study was twofold: (1) to test patterns of age-related change (i.e

25 e disassembly rate was accelerated more than twofold above the resting value, but only when contracti

26 The overall SIR remained increased twofold after 1 or more years of follow-up.

27 after 4 months, but increased gecko density twofold after 16 months, likely because the decay of fir

28 ncoding the Npas4 transcription factor, was >twofold altered (downregulated) in MET mice; strikingly,

29 bronchitic symptoms was increased by almost twofold among past users (odds ratio [OR], 1.85; 95% con

30 Incorporating polysorbate 80 resulted in 3 twofold and 2 twofold modal MIC decreases for Enterobact

31 ddition, HCV-infected patients experienced a twofold and a nearly 17-fold higher risk of MPGN (HR, 2.

32 nd budesonide reduced MR1 surface expression twofold and decreased NTHi-induced IFN-gamma secretion e

33 = 2.2 mmol(-1) . sec(-1)) were approximately twofold and fivefold lower, respectively, compared with

34 /G group demonstrated greater bone volume by twofold and higher osteoblast number by threefold, compa

35 pathogen loads, increasing disease more than twofold and increasing mortality up to eightfold.

36 lasma leucine concentration by approximately twofold and muscle p-mTOR(Ser2448) by approximately 30%

37 fully active increases cyclin B1 degradation twofold and reduces the length of this division by 2 h.

38 y toward the C18 fatty acyl-CoA substrate by twofold and significantly elevated 20-carbon (C20) LCB p

39 tochondria, enhances Sirt3 expression nearly twofold and suggest that HKL may bind to Sirt3 to furthe

40 ncrease of both optical transmittance (up to twofold) and electrical conductivity (up to two orders o

41 increased basal glucose uptake approximately twofold, and attenuated high-fat diet-induced basal TBC1

42 sulin increased glucose uptake approximately twofold, and caCaMKKalpha plus insulin increased glucose

43 -order reduction rate constant, k, decreased twofold, and the photoreduced Hg amount, Hg(II)red, incr

44 s a nematic component, confirming reports of twofold anisotropy in the broken symmetry state and stro

45 ere, the combined speedups are approximately twofold, approximately 1- to 60-fold, and approximately

46 r and induced PTTG transcriptional activity (twofold) as assessed by chromatin immunoprecipitation an

47 edly large, enhancing currents by as much as twofold at physiological voltages.

48 es to the mineral nucleation sites along the twofold axes.

49 rands are juxtaposed, creating an additional twofold axis along the filament.

50 ere the two Cas2 domains form a central hub (twofold axis of symmetry) flanked by two Cas1 lobes and

51 and replaces one dimer of coat proteins at a twofold axis.

52 mechanism has been proposed to mediate this twofold behavioral improvement: the rhythmic entrainment

53 nal mutations per year differed by more than twofold between families.

54 T( *) form of F2N12S were found to differ by twofold between Ld and Lo phases as a result of the rest

55 > 50% of abundant proteins varying more than twofold between the lowest and highest irradiance.

56 production in wild-type plants by more than twofold, but had no significant effect on pin6 lines.

57 D519V/E665V potency was increased twofold by the 2-stage chromogenic assay relative to BDD

58 able cascade process inducing the collective twofold C-H/threefold C-F bond activations, where each C

59 999 down-regulated transcripts with at least twofold change (FDR corrected p < 0.05) in needle tissue

60 ment but adjusts dynamically toward the same twofold change as development progresses.

61 Without optimization, the switch exhibited a twofold change in binding affinity for SspB with light s

62 lure in patients or conferred a greater than twofold change in susceptibility compared with a referen

63 differentially expressed genes (greater than twofold change) and their functional annotations.

64 Most importantly, while the twofold clustering did not differ significantly between

65 e increased the proportion of theaflavins by twofold compared to black tea.

66 tivity toward lead ions was raised more than twofold compared to the unmodified nanoparticles.

67 roportion of ca. 5% of total lipids was only twofold compared to total lipids.

68 table MRD, PNB nanosurgery improved survival twofold compared with standard surgery.

69 PTX by sevenfold compared with free drug and twofold compared with the Food and Drug Administration-a

70 tion energy by a factor of 2.7 larger in the twofold compared with the threefold polymorph, whereas D

71 ity toward Cs-conformers is templated by the twofold coordination to Ag adatoms.

72 ure B cell egress from BM was dependent on a twofold CXCR4 down-regulation that was antagonized by an

73 ministration of diabody (0.8 mg/kg) caused a twofold decrease in brain lesion size, whereas that of t

74 nds exhibited a 28% decrease in soil C and a twofold decrease in plant biomarkers, indicating microbi

75 2 allele is associated with an approximately twofold decreased risk for AD.

76 ent the order parameter of any system with a twofold degenerate broken-symmetry phase, including elec

77 ing owing to a participation of the bridging twofold degenerate oxygen's virtual singlet state are de

78 past 5 million years are responsible for the twofold difference in the sizes of these genomes.

79 transmembrane domain (TMD) but transition to twofold dimer-of-dimers symmetry for extracellular ligan

80 fter FP was greater in non-smokers (1.5- and twofold doubling dose difference from placebo after FP 1

81 quantified 518 twofold up-regulated and 811 twofold down-regulated proteins common to both AUY922 an

82 46, which showed consistent and reproducible twofold down-regulation in Bullies.

83 pollutants such as NOx and CO were enhanced twofold during PCAPs, O3 concentrations were approximate

84 Our results highlight a twofold effect of cholesterol on the amyloidogenicity of

85 pproximately 100-fold, whereas it had only a twofold effect on the rate of the first.

86 The results reveal that the mutation has a twofold effect.

87 Thus, desensitization had a twofold effect: It abbreviated signaling between IHC and

88 We further demonstrate a twofold enhancement in addressable focus resolution in a

89 d nanoalloy catalyst exhibits a greater than twofold enhancement in Faradaic efficiency for CO2 reduc

90 y 30 min of recovery time displayed a robust twofold enhancement in long-term potentiation (LTP) indu

91 but not VAMP, Cplx2, or synaptotagmin, were twofold enriched in SNAP25 immunoprecipitated products f

92 al cells in SR-1-treated hESCs, as well as a twofold expansion of CD34(+)CD45(+) hematopoietic progen

93 nriched RNAs that interacted with WT PKR (>/=twofold, false discovery rate </= 5%) were small nucleol

94 Telomeres exhibit approximately twofold fewer photoproducts compared with the bulk genom

95 Our contribution in this article is twofold: first, we bridge this unpleasant gap by present

96 mation, transcript levels increase more than twofold for ~900 genes and decrease by more than half fo

97 s more than eightfold during CE and can vary twofold from individual to individual, we have proposed

98 The importance of the result is twofold: from a fundamental viewpoint, the direct applic

99 leback population has evolved an approximate twofold gain in ventral pharyngeal tooth number compared

100 ever, the magnitude of increase in pCa50 was twofold greater at short SL than at long SL.

101 oss a 480-mm rainfall gradient, resulting in twofold greater carbon loss on average in historically w

102 ared to mitral cells, tufted cells exhibited twofold greater excitability and peak instantaneous firi

103 larger deformation fields and approximately twofold greater fiber alignment compared with FLNa KD ce

104 markedly insulin resistant and had more than twofold greater IMCL in the subsarcolemmal (SSL) region.

105 Vascular permeability was twofold greater in inflamed blood vessels in Nrp2-defici

106 icle was fivefold greater than free drug and twofold greater than Abraxane.

107 Our estimate of FCO2 is approximately twofold greater than previous estimates, as a result of

108 matic genomes encoding lincRNAs is more than twofold greater than the fraction of protein-coding sequ

109 boxykinase (PCK) photosynthetic pathways was twofold greater than the kcatc of Rubisco from NAD-ME sp

110 lecular dynamics simulation, we found that a twofold helical screw conformation of xylan is stable in

111 d helical screw in solution, flattens into a twofold helical screw ribbon to bind intimately to cellu

112 might allow the xylan backbone to fold as a twofold helical screw to facilitate alignment along, and

113 orated on alternate residues and folded as a twofold helical screw.

114 By 24 hours, twofold higher concentrations of platinum were detected

115 gans that recruit arthropod mutualists, have twofold higher diversification rates than families that

116 er, the promoter of murEUo5 , which drives a twofold higher expression compared to that of S. pneumon

117 (S) and octanoyl carnitine (O) were one- to twofold higher in eWAT of old mice (P < 0.05).

118 tive levels of PV protein were approximately twofold higher in PVBC boutons in adult animals, whereas

119 nfected hosts and infected fleas was roughly twofold higher in sites where large wildlife was absent.

120 and liver graft loss were about 1.2-fold and twofold higher in the LIST group.

121 mation, and their numbers were approximately twofold higher in wild-type mice than in Mac-1(-/-) mice

122 mation system (GIS) analysis, we uncovered a twofold higher incidence of Beijing strains in a hotspot

123 imulation by the littermates, support: (1) a twofold higher level of cortical activity than in the is

124 The results demonstrate a nearly twofold higher mortality rate among individuals with tre

125 discernible concentration reached as low as twofold higher or lower than basal concentration.

126 previous reports, HIV-positive patients had twofold higher risk of AR (adjusted relative risk [aRR],

127 obesity was associated with an approximately twofold higher risk of major complications: male patient

128 a) are shown to attain a stiffness, which is twofold higher than any known organic biogenic structure

129 per intergenic kilobase, was comparable and twofold higher than that found in the gene-dense genomes

130 The expression of miR-146a was approximately twofold higher than that of miR-146b in healthy human sk

131 articular, the endosperm 18:2 percentage was twofold higher than that of the embryo.

132 of T-bet(-/-) CD4(+)IFNgamma(+) T cells was twofold higher than wild-type CD4(+) T cells cultured in

133 The goal of the current study was twofold: (i) to characterize the relationship between br

134 ree height and survival, our objectives were twofold: (i) to identify the source of differential popu

135 -nucleophilic amino acids led to a more than twofold improvement in cyclopropanation performance (tot

136 ced dynamic response (PHId), and a more than twofold improvement in glucose tolerance (disposition in

137 teins were found to be reduced approximately twofold in clathrin-depleted cells as a whole and approx

138 erived endothelial precursor cells increased twofold in DMOG-treated wild-type mice (P < 0.001) but a

139 vels in the NAc were increased approximately twofold in EtOH mice compared with CTL mice, and this di

140 on increased PTTG mRNA and protein abundance twofold in HCT116 human colon cancer cells, and inductio

141 by 20-fold in low-salinity sediments and by twofold in mesohaline sediments, after one day.

142 d by ablation of blue cones, and are reduced twofold in mutant larval retina with few UV cones.

143 Fasting Adipo-IR was increased twofold in obese subjects with NGT and IGT versus lean s

144 LTP was augmented by twofold in R192Q mice, whereas LTD was unchanged compare

145 n was constant in the large MFG, but dropped twofold in the small MFG.

146 he frequency of spontaneous firing more than twofold in the two groups of interneurons, and more than

147 local background), decreasing steadily to a twofold increase 18 km downwind.

148 atients (ie, antibody titer above cutoff and twofold increase between pre and postvaccination values

149 [U-(13)C]glucose metabolism showed a twofold increase in alanine levels and sixfold increase

150 death due to growth limitation resulted in a twofold increase in allomer production, relative to chl-

151 reert2)/Met(fl/fl)/Apc(fl/fl) mice) caused a twofold increase in apoptosis in microadenomas, resultin

152 l vector expressing UT-B resulted in about a twofold increase in AXR at the site of virus injection.

153 ting "Rag-5xfAD" mice exhibit a greater than twofold increase in beta-amyloid (Abeta) pathology.

154 of the superior mesenteric artery revealed a twofold increase in blood flow velocity compared with tu

155 siderea corals within enrichment plots had a twofold increase in both the prevalence and severity of

156 for a reduction in microstrain along with a twofold increase in charge-carrier mobilities leading to

157 a study was conducted in Arabidopsis, where twofold increase in folates occurred in foliage upon SA

158 imulated with tumor necrosis factor (TNF), a twofold increase in GM-CSF was observed and related to e

159 However, the mutation causes a twofold increase in GTP-binding affinity of Roc, thus su

160 ith the co-benzothiadiazole polymer having a twofold increase in hole mobility when compared to the I

161 take into skeletal and cardiac muscle, and a twofold increase in insulin signaling in muscle.

162 abled the design of a mutant that displays a twofold increase in its off-to-on photoswitching quantum

163 th spirometric COPD (n = 6,436), there was a twofold increase in lung cancer incidence (incident rate

164 >/= 35 kg/m(2)) was associated with a nearly twofold increase in mortality (hazard ratio, 1.9; 95% co

165 ly, fibroblasts carrying the mutation showed twofold increase in proliferation rate associated with h

166 logical and morphometric analyses revealed a twofold increase in proliferative ECs and a 1.35-fold in

167 We also found a twofold increase in quaternary ammonium compounds in sal

168 with non-REM AHI less than or equal to 5, a twofold increase in REM AHI was associated with 24% high

169 evels often surpassing the power gained by a twofold increase in sample size.

170 Furthermore, a twofold increase in SCL levels in mice bearing a hypomor

171 the cell than conventional TFM, leading to a twofold increase in spatial resolution (of up to 500 nm)

172 rough an extensive field survey, we detect a twofold increase in species diversity in the surveyed ar

173 Stimulation-treated animals showed a twofold increase in synaptic density compared with SHAM.

174 re evident than during T-cell development: A twofold increase in the abundance of transcription facto

175 te the mutations conferring only a less than twofold increase in the affinity of its hemagglutinin fo

176 The resulting complex yielded a twofold increase in the amount of reducing sugars releas

177 ved from immature pig ovaries and provides a twofold increase in the efficiency of blastocyst product

178 with the PPO inhibitor tropolone produced a twofold increase in the phenolic fraction, which would t

179 domide augments NK-cell responses, causing a twofold increase in the proportion of primary NK cells p

180 wed the actin-induced powerstroke, despite a twofold increase in the rate constant for actin-activate

181 tissue culture cells results in a more than twofold increase in the rate of cell movement, in part d

182 e synthetic feed to color trout flesh (up to twofold increase in the retention of the main ketocarote

183 at lower decompression pressures is 8.2 K, a twofold increase in the same crystal structure as in com

184 discovered that cells lacking Ulp2 display a twofold increase in transcript levels across two particu

185 ATRX-deficient embryos exhibit a twofold increase in transcripts for aurora kinase B, the

186 dly, mice lacking hepatic lipogenesis have a twofold increase in tumour incidence and multiplicity co

187 A twofold increase in vesicular transport enhances the ves

188 Inhibition of OXPHOS induced a twofold increase in Vsteady-state and glycolytic ATP pro

189 fteen of 16 patients demonstrated at least a twofold increase of XPO1 mRNA, indicating inhibition of

190 A or jasplakinolide induces an approximately twofold increase or ~60% decrease, respectively, in solu

191 icans was observed to be more self-adherent (twofold increase) and formed higher biofilm mass (77% in

192 mulative survival (86% vs 75%, P = .017) and twofold increased hazard ratio (HR).

193 let-fibrin deposition after laser injury and twofold increased protection from bleeding in acute and

194 FMF was associated with more than twofold increased risk for death after transplantation,

195 that carriers of PLD3 coding variants have a twofold increased risk for LOAD and that PLD3 influences

196 carriers had higher mean birth weights and a twofold increased risk for type 2 diabetes with a 7-year

197 g dnDSA (vs. no dnDSA) was associated with a twofold increased risk of CLAD (hazard ratio, 2.04; 95%

198 s (BCAAs) are associated with a greater than twofold increased risk of future pancreatic cancer diagn

199 the lowest quartile (shortest) had an almost twofold increased risk of incident diabetes (hazard rati

200 479R and C394S mutations resulted in similar twofold increases in amiloride-sensitive ENaC current.

201 s, CRF+urocortin2, resulted in approximately twofold increases in peak Ca(2+) responses, whereas stim

202 Accompanying twofold increases in photosynthetic CO2-assimilation rat

203 o [(3)H]-2-deoxyglucose uptake approximately twofold, insulin increased glucose uptake approximately

204 A series of porous twofold interpenetrated In-Co(III) (porphyrin) metal-org

205 The twofold interpenetrating structure brings adjacent Co(II

206 ctional experiments implied an approximately twofold larger Ca(2+) channel density in high release pr

207 d liver fat compared with PUFAs and caused a twofold larger increase in VAT than PUFAs.

208 dent on myosin II activity and are more than twofold larger than stresses generated by cells of embry

209 onse during a burst was on average more than twofold larger than the response to the first spike.

210 sponsiveness of piriform neurons is at least twofold less sparse than currently believed.

211 s, we show that M1 (A213) exhibits an almost twofold lower dissociation constant with its primary tar

212 g polysorbate 80 resulted in 3 twofold and 2 twofold modal MIC decreases for Enterobacteriaceae and P

213 n-bundled actin filaments have approximately twofold more frequent and approximately fivefold longer

214 s were identified, and these were three- and twofold more likely, respectively, to encompass a known

215 in V. alginolyticus Faster cells accumulate twofold more tightly by chemotaxis compared with slower

216 it cell are related to each other by a local twofold noncrystallographic symmetry axis, a conformatio

217 ihood of not receiving adjuvant therapy over twofold [odds ratio (OR) = 2.20, 95% confidence interval

218 that RNA and protein expression were within twofold of expected levels 80% and 64% of the time, resp

219 Importantly, the IC50 for NSAH is within twofold of gemcitabine for growth inhibition of multiple

220 he overall increase in Et over land is about twofold of the decrease in Es.

221 g polypyrimidines although decreasing nearly twofold on ssDNA containing equal amounts of the four ba

222 ained seven unnamed compounds that displayed twofold or greater abundance in dry or rehydrating state

223 f genes that are differentially expressed by twofold or greater in the Bullies; one of these was a pu

224 ds of these mRNAs have increased half-lives (twofold or more) in Mettl3 knockout cells compared with

225 ction of amorphadiene, the final product, by twofold over that from inducible or constitutive promote

226 centrations, which decreased from tenfold to twofold over the same distance, but the spatial patterns

227 germinal vesicle stage, including more than twofold overexpression of the histone methyltransferase

228 sed the odds of having an infant with BPD by twofold (P = 0.02).

229 eexisting hypertension was associated with a twofold (P = 0.04) increase in odds for BPD.

230 ted significantly increased speed (more than twofold, P < .0001), with mean repetition times compared

231 xenografts, were significantly higher (about twofold, P < 0.0001), compared with non-expressing contr

232 imately 50%, P < 0.01), angiogenic capacity (twofold, P < 0.05) and expression of vascular endothelia

233 the expression levels of the full-length AR (twofold, P < 0.05) and the AR splice variants 1 (threefo

234 mutations produced substantial (greater than twofold) phenotypes of either increased or decreased spl

235 VIII-deficient mouse models, approximately a twofold prolonged half-life in mice, rabbits, and cynomo

236 n Sestrin2 (hSesn2), and show that hSesn2 is twofold pseudo-symmetric with two globular subdomains, w

237 The twofold purpose of this systematic review was to: (i) pr

238 ymous changes at Thr6 and Leu9 resulted in a twofold range in FlgM activity.

239 rther show that the R1441H mutation causes a twofold reduction in GTPase activity without affecting t

240 n per dot on average, we achieve a more than twofold reduction in the amplified spontaneous emission

241 cedented efficiency of 80%, accompanied by a twofold reduction in the exciton binding energy.

242 considering the total amount of volatiles, a twofold reduction was observed.

243 located adjacent to seagrass meadows showed twofold reductions in disease levels compared to corals

244 Notch is further characterized by a twofold relationship with its Delta-Serrate (DSL) ligand

245 ed illumination microscopy (MSIM) provides a twofold resolution enhancement beyond the diffraction li

246 ion intensities, but typically offers only a twofold resolution gain.

247 undance in culture supernatants by five- and twofold, respectively.

248 onding to cytosolic signals and initiating a twofold response.

249 nce of degenerating axons is mechanistically twofold, resulting from deferred initiation of axonal WD

250 ombined results support the hypothesis for a twofold role of K in the mechanism of membrane fusion: 1

251 e risk of: uncontrolled asthma was increased twofold (RR 1.96 (95% CI 1.25-3.07)); severe asthma and

252 uently, xylan adopts a flattened ribbon-like twofold screw conformation when bound to cellulose in th

253 The twofold screw xylan is spatially close to cellulose, and

254 critical for achieving an effective HTP, is twofold: shutting down the radically induced chain-growt

255 I state and consequently to an approximately twofold slower release of all-trans-retinal from rhodops

256 IHCs), but their Ca(2+) current density was twofold smaller because of a smaller open probability an

257 We also observe a twofold steepening of the relationship between sea level

258 tory of CT+ women exhibited an approximately twofold steeper increase after the pCRH inflection point

259 mineralization processes the organisms use a twofold strategy to control magnetite formation: the min

260 ff-responses after termination of touch were twofold stronger than responses to vocalizations.

261 to 77 mum, the specific surface increases by twofold, structural integrity was lost and water extract

262 siRNA-L2 tumor accumulation diminished only twofold, suggesting that the superior tumor distribution

263 ANE contribution of the isolated FM alloy is twofold, surface and bulk.

264 blockers and magnesium, and a approximately twofold symmetric arrangement of ion channel pore loops.

265 materials change from fourfold symmetric to twofold symmetric at temperatures corresponding to the o

266 the dynamics in the threefold symmetric and twofold symmetric polymorphs of native Abeta as well as

267 In the twofold symmetric tetramer, 44 nucleotides bind in a clo

268 TRAAK channels are twofold symmetric, which precludes a direct extension of

269 display domains of anisotropic friction with twofold symmetry and anisotropy exceeding 200%.

270 dimer of GluN1-GluN2B heterodimers with the twofold symmetry axis running through the entire molecul

271 in hexamers (intrahexamer) and threefold and twofold symmetry between neighboring hexamers (interhexa

272 l is built as a dual-topology homodimer with twofold symmetry parallel to the membrane plane.

273 homometallic congeners, due to threefold-to-twofold symmetry reduction, resulting in cuprophilic sen

274 Here, we take on the twofold task of deriving features directly from empirica

275 lucose transport was less (P < 0.01) in T2D (twofold) than in NW (sevenfold) or OB (sixfold) subjects

276 Together, the pathogenic effects of MDM2 are twofold, that is, p53-independent NF-kappaB activation i

277 oop mutations that reduced the koff value by twofold, these mutations resulted in an overall selectiv

278 of chlorinated arenes and (hetero)arenes are twofold: they are useful in tuning electronic structure

279 he rates of many cellular processes increase twofold, threefold, or many-fold for each 10 degrees C i

280 e blood were desensitized by incubation with twofold to 2.5-fold increasing allergen doses in 10 step

281 -silenced osteosarcoma cells caused a marked twofold to fivefold decrease in spontaneous lung metasta

282 R/Cas9 cleavage, increases HDR efficiency by twofold to fivefold relative to circular plasmid donors

283 UT1, GLUT3, GLUT6, and GLUT10 protein levels twofold to fivefold.

284 in self-renewing proliferation leading to a twofold to fourfold expansion of the HSPC pool in the BM

285 y early-onset severe portal hypertension and twofold to fourfold increase in profibrogenic transcript

286 Diabetic patients have a twofold to fourfold increased risk of cardiovascular dis

287 A twofold to threefold enhancement in endoplasmic reticulu

288 l sensitivity, whereas the average neuron is twofold to threefold less sensitive than the animal.

289 ression, resulting in a subset of Tregs with twofold- to fivefold-lower levels of FoxP3 protein.

290 Our objectives were twofold: to evaluate the incidence and time to recovery

291 The aim of this study was twofold: to explore potential age- and sex-specific thre

292 Our proteomic study quantified 518 twofold up-regulated and 811 twofold down-regulated prot

293 ome degeneration, X-linked genes have become twofold up-regulated, restoring ancestral expression lev

294 ogically essential vitamins, with an overall twofold up-regulation of expression compared with free-l

295 ng relaxation time maps demonstrated up to a twofold variation in mean regional T1 and T2 after ablat

296 from the injured SVZ increased approximately twofold versus controls, and, upon differentiation, more

297 ncreased colony-forming unit MK cell numbers twofold vs control in clonogenic assays, without substan

298 The goals of this study were twofold; we sought to (1) identify the molecular mechani

299 These levels increased additionally twofold when the stored samples were heated (40 degrees

300 discriminative power of the correlations by twofold, yielding >50% predictive improvement over tradi