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1 m microvascular complications in adults with type 2 diabetes.
2 ontribute to glucolipotoxicity that leads to type 2 diabetes.
3 ys is a relatively new strategy for treating type 2 diabetes.
4 tion and may contribute to increased risk of type 2 diabetes.
5 ng disorder, cocaine addiction, obesity, and type 2 diabetes.
6 ure of chronic disorders such as obesity and type 2 diabetes.
7 ways easy to distinguish LADA from type 1 or type 2 diabetes.
8 als with prediabetes who were diagnosed with type 2 diabetes.
9 er-2 inhibitor approved for the treatment of type 2 diabetes.
10 ic lipid deposition, insulin resistance, and type 2 diabetes.
11 logs a useful and safe treatment modality in type 2 diabetes.
12 syndrome and 1.37 (1.03-1.82; P = 0.021) for type 2 diabetes.
13 pression patterns of neutrophil receptors in type 2 diabetes.
14 5 as a potential target to prevent and treat type 2 diabetes.
15 ammation plays a key role in both type 1 and type 2 diabetes.
16 ndividuals and reduces comorbidities such as type 2 diabetes.
17 ose-lowering medication in participants with type 2 diabetes.
18 fy this important issue in the management of type 2 diabetes.
19 n of risk of complications for patients with type 2 diabetes.
20 nt a new class of therapeutic agent to fight type 2 diabetes.
21 emorrhagic, and 79578 other), and 67914 from type 2 diabetes.
22 over 2 y using MRI in overweight adults with type 2 diabetes.
23 ts is described as a potential treatment for type 2 diabetes.
24 y studied in persons with type 1 diabetes or type 2 diabetes.
25 isease, and dysregulation of inflammation in type 2 diabetes.
26 T cell MHP was not detected in subjects with type 2 diabetes.
27 simplistically lumped into the large pool of type 2 diabetes.
28 control participants and five patients with type 2 diabetes.
29 pathway signaling in islets from donors with type 2 diabetes.
30 sed blood levels of glucose in patients with type 2 diabetes.
31 rative effectiveness of oral medications for type 2 diabetes.
32 waist-to-hip ratio, and an increased risk of type 2 diabetes.
33 nabled development of new medicines to treat type 2 diabetes.
34 optosis is an important disease mechanism in type 2 diabetes.
35 spectroscopy in 449 individuals at risk for type 2 diabetes.
36 OSA is associated with STDR in patients with type 2 diabetes.
37 e assessed this risk long term in women with type 2 diabetes.
38 -years, we identified 4347 cases of incident type 2 diabetes.
39 tion, with relevance to human physiology and type 2 diabetes.
40 ex and all-cause mortality among people with type 2 diabetes.
41 a strategy that may reduce beta-cell loss in type 2 diabetes.
42 production (HGP) represents a key feature of type 2 diabetes.
43 ls is a major contributor to the etiology of type 2 diabetes.
44 n maintain glycemic control in patients with type 2 diabetes.
45 ss of ovarian estrogens is a risk factor for type 2 diabetes.
46 or other obesity-related morbidity, such as type 2 diabetes.
47 rget patient population includes adults with type 2 diabetes.
48 s of DR in many but not in all patients with type 2 diabetes.
49 apine often induce excessive weight gain and type 2 diabetes.
50 sured in peripheral blood in the etiology of type 2 diabetes.
51 y yield insights into the pathophysiology of type 2 diabetes.
52 uld serve as potential drug targets to treat type 2 diabetes.
53 and PDR) with incident CVD in patients with type 2 diabetes.
54 enia is associated with an increased risk of type 2 diabetes.
55 s that enhance GLP-1 levels in patients with type 2 diabetes.
56 pectives in the pharmacological treatment of type 2 diabetes.
57 h as the prevention of metabolic syndrome or type 2 diabetes.
58 et diabetes of the young form 3 (MODY 3) and type 2 diabetes.
59 Of these patients, most (98%) had type 2 diabetes.
60 are increasingly being used as treatment for type 2 diabetes.
61 in fasting plasma insulin level and risk of type 2 diabetes.
62 ociated with an increased risk of developing type 2 diabetes.
63 x and lysosomal staining in human samples of type 2 diabetes.
64 importance for the treatment of obesity and type-2 diabetes.
66 416 patients aged >/=25 years with type 1 or type 2 diabetes, a serum creatinine (SCr) level of 1.3-3
68 anagement of hyperglycaemia in patients with type 2 diabetes admitted to general medicine and surgery
69 ased drugs in the treatment of patients with type 2 diabetes admitted to hospital has not been extens
70 ariants associated with an increased risk of type 2 diabetes affect the function of a monocarboxylate
72 ed end point trial, consenting patients with type 2 diabetes aged >18 years, with waist circumference
73 articipants were insulin-naive patients with type 2 diabetes, aged 18 years and older, who had insuff
76 and novel IAPP analogs for the management of type 2 diabetes, Alzheimer's disease, or other diseases
77 Program (DPP), a trial for the prevention of type 2 diabetes among high-risk individuals, we quantifi
80 RPRETATION: In a population of patients with type 2 diabetes and a broad cardiovascular risk profile,
81 SA, enrolling patients aged 18-80 years with type 2 diabetes and a random blood glucose concentration
82 usions In two trials involving patients with type 2 diabetes and an elevated risk of cardiovascular d
83 reased in skeletal muscle from patients with type 2 diabetes and are decreased following endurance tr
85 flammation has been associated with incident type 2 diabetes and atherosclerotic cardiovascular disea
86 BMI), a measure of abdominal adiposity, with type 2 diabetes and CHD through the potential intermedia
88 rns have been associated with lower risks of type 2 diabetes and coronary artery disease, but their r
90 s Network, we apply each feature of PLATO to type 2 diabetes and demonstrate how PLATO can be used to
92 pants were selected based on the presence of type 2 diabetes and either prevalent CVD or CVD risk fac
93 adult patients (aged 18 years or older) with type 2 diabetes and had a primary outcome including, but
94 de 1 analogue, with placebo in patients with type 2 diabetes and high cardiovascular risk who were re
95 beta-cells and down-regulated in type 1 and type 2 diabetes and in infiltrating activated immune cel
98 utcomes of metformin use in populations with type 2 diabetes and moderate to severe chronic kidney di
100 peutic targets in metabolic diseases such as type 2 diabetes and non-alcoholic fatty liver disease.
101 ex (BMI), physical activity, alcohol intake, type 2 diabetes and parity, use of hormone replacement t
106 has long-term benefits for the prevention of type 2 diabetes and that arachidonic acid is not harmful
107 omising causal paths to and from glucose and type 2 diabetes and underline the value of additional in
109 le decreased risk of Parkinson's disease and type-2 diabetes and an increased risk of pregnancy loss.
110 meta-analysis of prospective cohort studies (type 2 diabetes), and a prospective cohort study (dental
111 se measurements captured by individuals with type 2 diabetes, and against predictions generated by ex
116 n of this score with cardiometabolic traits, type 2 diabetes, and CHD was tested in a mendelian rando
117 py in reducing hyperglycemia in persons with type 2 diabetes, and has been associated with reduced mo
118 mplicated in the beta cells of patients with type 2 diabetes, and in the beta cells of obese diabetic
119 rtriglyceridemia, severe insulin resistance, type 2 diabetes, and nonalcoholic steatohepatitis (NASH)
120 genes are relevant in the pathophysiology of type 2 diabetes, and that mitochondrial BCAA management
124 ditions including heart disease, stroke, and type 2 diabetes are leading causes of preventable death.
131 fic and tailored management of patients with type 2 diabetes, as has been shown in patients with matu
134 ng the patients in the surgery group who had type 2 diabetes at baseline, type 2 diabetes remitted in
137 etitian as part of lifestyle intervention in type 2 diabetes, but further randomized studies are warr
138 models of type 1 diabetes and two models of type 2 diabetes by adeno-associated virus delivery of re
139 focused on Spry2-a gene implicated in human type 2 diabetes by genome-wide association studies but w
140 ed by obesity, and are at risk of developing type 2 diabetes, cardiovascular disease and related meta
141 proved HbA1c and bodyweight in patients with type 2 diabetes compared with placebo, and showed a simi
142 nd comorbidities was higher among those with type 2 diabetes compared with type 1, but frequent in bo
143 k individuals are twice as likely to develop type 2 diabetes compared with white individuals, and the
145 bolic multimorbidity (ie, at least two from: type 2 diabetes, coronary heart disease, and stroke) in
146 Because few insulin-treated patients with type 2 diabetes currently use CGM, these results support
147 including 2018 participants with type 1 and type 2 diabetes diagnosed at younger than 20 years, with
149 elopments in the diagnosis and management of type 2 diabetes, existing controversies, and future dire
150 eing significantly associated with prevalent type 2 diabetes for participants with high dietary fat i
151 ypertension risks, using 3,448 patients with type 2 diabetes from the ADVANCE study (Action in Diabet
152 AEs for osteoporosis, hypertension, obesity, type 2 diabetes, gastrointestinal ulcers/bleeds, fractur
153 old woman with a history of hypertension and type 2 diabetes had been in her usual state of health un
155 diabetes and controls, whereas patients with type 2 diabetes had smaller reductions in fatal outcomes
156 h type 1 diabetes and 42.2% of patients with type 2 diabetes had undergone an eye examination by 6 ye
157 e, evidence is accumulating that young-onset type 2 diabetes has a more aggressive disease phenotype,
161 s such as asthma, food allergies, type 1 and type 2 diabetes, hepatic steatosis, cardiovascular disea
162 ological treatment options are available for type 2 diabetes; however, many patients do not achieve o
163 ction against metabolic syndromes, including type 2 diabetes; however, mechanisms that are associated
166 s emerging evidence on the increased risk of type 2 diabetes in association with antidepressant use.
169 antidepressant use and the risk of incident type 2 diabetes in youths by antidepressant subclass and
170 a new drug target for insulin resistance in Type-2 diabetes, in which the unmet therapeutic need rem
171 currently using SSRIs or SNRIs, the risk of type 2 diabetes increased with the duration of use (RR,
177 rial fibrillation, and in the setting of AF, type 2 diabetes is independently associated with a 2% to
183 %]; 4505 white [82.6%]) and 7233 youths with type 2 diabetes (median age at initial diagnosis, 19 yea
185 assessed the first documented occurrence of type 2 diabetes mellitus (DM), chronic kidney disease (C
186 Over the past decades, the prevalence of type 2 diabetes mellitus (T2D) has been steadily increas
187 ividual CC lines were identified that showed type 2 diabetes mellitus (t2DM) development and signific
188 on between fruit consumption and the risk of type 2 diabetes mellitus (T2DM) have been inconsistent.W
190 However, endurance trained athletes and type 2 diabetes mellitus (T2DM) patients store similar a
195 lar morbidity and mortality in patients with type 2 diabetes mellitus and established cardiovascular
196 tively associated with age, body mass index, type 2 diabetes mellitus and inversely with estimated gl
198 Secretion of this hormone is dysregulated in type 2 diabetes mellitus but the mechanisms controlling
199 ines for glycated hemoglobin A1c testing for type 2 diabetes mellitus could be improved to bring them
200 at baseline, of whom 67% had a diagnosis of type 2 diabetes mellitus for >10 years, 58% were receivi
201 m METASTROKE (12 389 ischemic stroke cases), type 2 diabetes mellitus from DIAGRAM (Diabetes Genetics
203 in a post hoc analysis in 1147 patients with type 2 diabetes mellitus on hemodialysis who participate
205 ) randomly assigned 10 142 participants with type 2 diabetes mellitus to canagliflozin or placebo.
206 ease, spanning conditions such as obesity to type 2 diabetes mellitus with excess cardiovascular risk
207 ed a substantial proportion of patients with type 2 diabetes mellitus without clinically recognized e
208 nd adipokine abnormalities (the hallmarks of type 2 diabetes mellitus) are characteristic features of
209 of islet-amyloid polypeptide associated with type 2 diabetes mellitus, a-synuclein associated with Pa
210 ted States, including obesity, hypertension, type 2 diabetes mellitus, and cardiovascular disease.
211 chronic hypertension, hypercholesterolemia, type 2 diabetes mellitus, and changes in body mass index
212 metformin, a first-line therapeutic drug for type 2 diabetes mellitus, and nelfinavir, an HIV proteas
213 preclinical candidates for the treatment of type 2 diabetes mellitus, as well as a promising startin
214 flozin on clinical outcomes in patients with type 2 diabetes mellitus, established cardiovascular dis
222 ugh overall still a rare disease, adolescent type 2 diabetes now poses major challenges to paediatric
223 was associated with a 2% increase in risk of type 2 diabetes (odds ratio 1.02, 95% CI 1.01-1.03, P =
224 -12)), ulcerative colitis (P<1.0 x 10(-20)), type 2 diabetes (P=2.8 x 10(-13)), hip/waist circumferen
225 dy mass index (P=2.2x10(-5)) and the risk of type 2 diabetes (P=6.1x10(-4)) associated with the risk
228 After matching for age, sex, hypertension, type 2 diabetes, previous stroke, and anticoagulation, i
230 Despite recommendations, many patients with type 2 diabetes receive dietary advice from nurses or do
231 is of a clinical trial in 1450 patients with type 2 diabetes receiving metformin and randomly assigne
232 mine the effectiveness of CGM in adults with type 2 diabetes receiving multiple daily injections of i
234 y group who had type 2 diabetes at baseline, type 2 diabetes remitted in 66 of 88 patients (75%) at 2
235 tty liver disease, hazardous alcohol use, or type 2 diabetes, reported higher prevalence of advanced
237 Aging is associated with increased risk for type 2 diabetes, resulting from reduced insulin sensitiv
240 and environmental determinants of type 1 and type 2 diabetes risk and progression, as well as complic
241 arker were not significantly associated with type 2 diabetes risk overall (RR per interquintile range
244 1, 118 unique associations between published type 2 diabetes single nucleotide polymorphisms (SNPs) a
247 Although a large proportion of patients with type 2 diabetes (T2D) accumulate misfolded aggregates co
248 cated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and assess glycemic control in pat
250 change in islet mass in different stages of type 2 diabetes (T2D) as measured by noninvasive imaging
254 ew genome-wide association studies (GWAS) of type 2 diabetes (T2D) have been conducted in U.S Hispani
256 isk in cohort studies, while the relation to type 2 diabetes (T2D) in the elderly remains unclear.
263 polypeptide (IAPP), which is associated with type 2 diabetes (T2D), with the Alzheimer's disease amyl
271 n saturated fatty acids and the incidence of type 2 diabetes (T2D).A prospective cohort analysis of 3
272 glucose and plasma insulin in patients with type 2 diabetes (T2D).A randomized crossover clinical tr
273 reduction of macrovascular complications in type 2 diabetes (T2D); however, the underlying mechanism
274 mediators in cardiovascular complications of type 2 diabetes (T2D); however, their contribution to Ch
281 ass-was associated with an increased risk of type 2 diabetes that intensified with increasing duratio
283 min, an anti-diabetic drug commonly used for type 2 diabetes therapy, is associated with anti-angioge
284 cs of type 1 diabetes differed from those of type 2 diabetes: they had a lower BMI (27.4 kg/m(2) [95%
285 ceived multiple daily insulin injections for type 2 diabetes used CGM on a daily or near-daily basis
286 blood pressure, coronary artery disease, and type 2 diabetes using data from six independent GWAS con
287 actors measured over time, participants with type 2 diabetes vs those with type 1 had significantly h
288 rated health, smoking status, triglycerides, type 2 diabetes, waist-hip ratio, attention deficit hype
289 ght, obesity, smoking status, triglycerides, type 2 diabetes, waist-hip ratio, childhood cognitive ab
292 In this longitudinal study of patients with type 2 diabetes, we found no association between TZD use
293 associated with a reduced risk of developing type 2 diabetes.We tested whether pomegranate polyphenol
294 nicians prescribe metformin to patients with type 2 diabetes when pharmacologic therapy is needed to
295 present in more than 90% of individuals with type 2 diabetes, where it contributes to beta-cell apopt
297 th cognitive function in older patients with type 2 diabetes who are carriers of the haptoglobin (Hp)
299 e National Eye Center among 50 patients with type 2 diabetes with and without DR (n = 100 eyes).
300 sed to examine the eyes of participants with type 2 diabetes with or without DR and the eyes of parti
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