ライフサイエンスコーパス: type 4

1 nd death from toxicity or unknown recurrence type, 4%.

2 ly susceptible to infection by dengue virus (type 4).

3 RPV4 (transient receptor potential vanilloid type 4).

4 tes and maturity-onset diabetes of the young type 4.

5 in, alpha(X)beta(2), the complement receptor type 4.

6 3 than after dose 2 for all serotypes except type 4.

7 ly identified B. anthracis pagA types except type 4.

8 ions in SOX10 result in Waardenburg syndrome type 4.

9 her known adenoviruses, including adenovirus type 4.

10 ent and functions as the complement receptor type 4.

11 oxisomal 17beta-hydroxysteroid dehydrogenase type 4.

12 Most of the liver-related deaths were in type 4.

13 idemiology and clinical presentation of HPIV type 4.

14 in is greatly reduced compared with the wild type; 4.

15 up to six distinct, narrowly tuned spectral types [4].

16 -13 only in T cells (4-13Tko) or in all cell types (4-13ko).

17 tide precursor and may involve a Diels-Alder-type [4 + 2] cycloaddition reaction.

18 : type 1, 50%; type 2, 18%; type 3, 23%; and type 4, 4%.

19 t (scFv) contains 14 mutations from the wild-type 4-4-20 scFv and has a 1800-fold increase in fluores

20 Seroprevalence was highest for HPV types 4 (46%), 1 (37%), and 8 (31%) in men and for types

21 4 (46%), 1 (37%), and 8 (31%) in men and for types 4 (47%), 63 (34%), and 1 (33%) in women.

22 sulin-stimulated NO release (mean [SEM] wild type 4,500 AU [1,000], hIGFREO 1,500 AU [700]; P < 0.05)

23 n those observed in the wild-type mice (wild-type, 4.58 +/- 0.25 mm; transgenic, 9.83 +/- 1.05 mm).

24 napses (types 1-3; 94%), whereas a minority (type 4, 6%) established symmetric synaptic contacts and

25 .008 for skin type 2, and P < .001 for skin types 4-6).

26 e tumor) were similar for all three antibody types (4.6-6.0), demonstrating the antigen specificity o

27 gether with the variability observed in wild-type [4] [6] and genetically manipulated mice ([6] and o

28 In a staged approach, we first typed 4,608 SNPs in case-control populations from four U

29 yos from matings of Hdh (+/-) mice with wild-type 4-8 cell embryos.

30 2.41 [95% CI, 1.24-4.70]); maternal AB blood type (4.9% stillbirths, 3.0% live births) (vs type O; AO

31 s significantly reduced compared to the wild type, 4.9 +/- 0.5 micromol/min/mg of protein (n = 7) and

32 dy, we tested whether adeno-associated virus type 4 (AAV4) vectors could mediate global functional an

33 The structure of AAV type 4 (AAV4), one of the most antigenically distinct se

34 We found that the CXC chemokine receptor type 4 accommodated the results better than the other te

35 Infections of adenovirus type 4 (Ad4) and Ad7 were discovered among previously va

36 report the x-ray crystal structure of the Ad type 4 (Ad4) E3-19K of species E bound to HLA-A2 at 2.64

37 ear hiatus, oral vaccines against adenovirus types 4 (Ad4) and 7 (Ad7) were again produced and admini

38 agonist (Lotronex, GlaxoSmithKline) and 5-HT type 4 agonist (Zelnorm, Novartis, AB) drugs on the dyna

39 asymmetric reduction of prochiral ketones of type 4-alkylidene cyclohexanone with formation of the co

40 (transforming growth factor beta1, collagen type 4 alpha 1, matrix metalloproteinase 2, and alpha-sm

41 We report that collagen type 4 alpha3-deficient mice with Alport syndrome-relate

42 e 2 (AOA2) and amyotrophic lateral sclerosis type 4 (ALS4).

43 a strong influence of the stereochemistry of type 4 aminotetraline-derived agonists on functional sel

44 ease of antiangiogenic fragments of collagen type 4 and 18.

45 and compare the spectroscopic properties of type 4 and type 1 CRYs.

46 (50)) in mice of isolates of two major phage types (4 and 8).

47 uppressed EGFR, whereas E1A12S of adenovirus types 4 and 40 had no effect on EGFR expression.

48 of electrophysiological cell phenotypes from types 4 and 5 cells (astrocytes) to type 1 cells (neuron

49 Type 2 and 3 cells expressed DCX, types 4 and 5 cells expressed GFAP, and type 1 cells exp

50 th (types 1, 2, and 3) or procedure related (Types 4 and 5) and examined events occurring early and a

51 emi-formed stools (Bristol Stool Form Scale, Types 4 and 5) per day with no nocturnal diarrhea, urgen

52 the attachment receptors for AAV type 2 and types 4 and 5, respectively.

53 ites (types 1, 4, and 6), Solanum pennellii (types 4 and 6), Solanum arcanum (type 6), and Solanum pi

54 The 1996 production halt of adenovirus types 4 and 7 vaccines prompted concerns about the resur

55 91 % of medium-diameter DRG cells (including type 4) and in 67 % of large-diameter DRG cells, but not

56 l cell-derived factor-1+, chemokine receptor type 4+, and von Willebrand factor+ cells, and vessels i

57 After 46.6+/-4.3 days, CLG type 2, type 4, and purified CLG were applied in vitro (n=1) to

58 2B; Marfan syndrome; Ehlers-Danlos syndrome type 4; and juvenile glaucoma.

59 he basal ganglia and cerebellum and dystonia type 4 are the extremes.

60 s with dengue virus type 2 (and dengue virus type 4) are largely subclinical.

61 entiation 36) and GLUT4 (glucose transporter type 4), are also unchanged.

62 Some types of OFF bipolar cells, type 3b and type 4 bipolar cells, had defects in dendrite arborizati

63 ypes of bipolar cells, including type 3b and type 4 bipolar cells.

64 As bone morphogenetic protein type 4 (BMP4) regulates Msx2 expression in embryonic tis

65 Male smokers, maxillary first molars, and type 4 bone had increased failure rates.

66 V-11, -16, and -18 and bovine papillomavirus type 4 (BPV-4) E2 and is also required for the respectiv

67 The expression of bovine papillomavirus type 4 (BPV-4) E7 overcame this arrest and lead to the d

68 wo-dimensional (2D) elastic crystals, of the type 4-bromophenyl 4'-nitrobenzoate where the halogen bo

69 Rolipram-inhibitable (type 4) but not calcium-calmodulin augmented (type 1) PD

70 ntification of the gene (NPHP4) causing NPHP type 4, by use of high-resolution haplotype analysis and

71 By blocking cAMP degradation, type 4 cAMP phosphodiesterase (PDE4) inhibitors activate

72 P signaling pathway by rolipram, a selective Type 4 cAMP phosphodiesterase inhibitor, reverses MK-801

73 P signaling in vivo, we have inactivated the type 4 cAMP-specific PDE (PDE4D) gene, a mammalian homol

74 ted LPS responses in mice deficient in PDE4 (type 4 cAMP-specific PDE)-B and PDE4D.

75 nd the combination of C-C chemokine receptor type 4 (CCR4) chemokine receptors and beta1 and beta3 in

76 ceptor type 5 and chemokine-related receptor type 4 (CCR5 and CXCR4) on peripheral blood mononuclear

77 s strongly expressed by diffuse cone bipolar type 4 cells (DB4; marked with anti-PKCalpha) and weakly

78 -insensitive K(+) and small Na(+) currents; type 4 cells, with slowly activating, large linear outwa

79 e-2 vasopressin, type-1 angiotensin, and CXC type-4 chemokine receptors, but not for the prostaglandi

80 ydration of crotonyl-CoA, absent in the wild-type 4-chlorobenzoyl-CoA dehalogenase, was shown to occu

81 tion into 5 pulsed-field gel electrophoresis types, 4 coagulase types, and 2 ribotypes.

82 stains, and labels immunohistochemically for type 4 collagen.

83 amide, i.e. a blood group O determinant on a type 4 core chain, the generalist strain bound to the Gl

84 1Cer), i.e. a blood group A determinant on a type 4 core chain.

85 d Arabidopsis CRY1 neither insect type 1 nor type 4 CRYs have autokinase activities.

86 Here we describe the purification of type 4 CRYs of zebrafish and chicken as recombinant prot

87 y the inhibitors of C-X-C chemokine receptor type 4 (CXCR4) and C-C chemokine receptor type 1 (CCR1),

88 r mechanism for the C-X-C chemokine receptor type 4 (CXCR4) antagonist 1 (AMD3100), a template with t

89 over, Plg regulated C-X-C chemokine receptor type 4 (CXCR4) expression in stem cells in vivo and in v

90 high expression of C-X-C chemokine receptor type 4 (CXCR4) mutation in Waldenstrom macroglobulinemia

91 The SDF-1alpha/C-X-C receptor type 4 (CXCR4) pathway directly promotes hepatic stellat

92 The C-X-C chemokine receptor type 4 (CXCR4) plays a crucial role in modulating cell t

93 very high levels of C-X-C chemokine receptor type 4 (CXCR4) production.

94 ively targeting the C-X-C chemokine receptor type 4 (CXCR4) was found to be an allosteric agonist, ac

95 ion of the cytokine C-X-C chemokine receptor type 4 (Cxcr4), an established regulator of this process

96 itory activity on the CXC chemokine receptor type 4 (CXCR4), toxicity properties, and assessment of t

97 The C-X-C chemokine receptor type 4 (CXCR4)/stromal cell derived factor-1 (SDF-1 or C

98 Type 4 cyclic adenosine monophosphate (cAMP) phosphodies

99 tosis following treatment with inhibitors of type 4 cyclic nucleotide phosphodiesterase (PDE4), a pro

100 Here, we provide evidence that type 4 cyclic nucleotide phosphodiesterases (PDE4s) are

101 Previous work suggested that dopamine type 4 (D4) receptors modulate neurohypophysial K+ curre

102 The live attenuated dengue virus type 4 (DEN-4) vaccine candidate virus rDEN4 Delta 30 wa

103 which was originally created in dengue virus type 4 (DEN4) by the removal of nucleotides 172 to 143 f

104 harge-to-alanine mutagenesis of dengue virus type 4 (DEN4) NS5 gene generated a collection of attenua

105 A recombinant live attenuated dengue virus type 4 (DEN4) vaccine candidate, 2ADelta30, was found pr

106 achieved by chimerization with dengue virus type 4 (DEN4).

107 ibody (MAb) 5H2 is specific for dengue virus type 4 (DENV-4) and neutralizes the virus at a high tite

108 Three dengue virus type 4 (DENV-4) vaccine candidates containing deletions

109 rders, type 3 (e.g., hepatitis C virus), and type 4 (dicistroviruses).

110 associations between novelty seeking and the type 4 dopamine receptor gene (DRD4), although a more re

111 Dystonia type 4 (DYT4) was first described in a large family from

112 is mutated in the movement disorder dystonia type 4 (DYT4).

113 (HSV-1) VP22 (HVP22) and equine herpesvirus type 4 (EHV-4) tk (Etk) were constructed in order to eva

114 an early infantile epileptic encephalopathy type 4 (EIEE4) patient carrying a de novo mutation in ST

115 lated to its inhibition of phosphodiesterase type 4 enzymatic activity.

116 or macrophage-specific deletion of the PGE2 type 4 (EP4) receptor induced salt-sensitive hypertensio

117 FGFR type 4 (FGFR4) in liver parenchymal cells binds only FGF

118 Familial Hemophagocytic Lymphohistiocytosis type 4 (FHL4) patient.

119 familial hemophagocytic lymphohistiocytosis type 4 (FHL4), a life-threatening disease of severe hype

120 most commonly involved with the formation of type 4 fimbriae and other surface-associated protein com

121 esponse modelling with a variety of particle types (>4), for the first-time a particle track structur

122 it, IL-3Ralpha, and C-X-C chemokine receptor type 4 from either human ECs or embryonic quail vessel e

123 and objective response, glucose transporter type 4 (GLUT4) expression, and KIT/PDGFRA mutation statu

124 persistent cell surface glucose transporter type 4 (GLUT4) in adipocytes resulting from impaired fun

125 The glucose transporter type 4 (glut4) is critical for metabolic homeostasis.

126 cyclohydrolase-mediated glucose transporter type 4 (GLUT4) translocation.

127 ately 31%) the levels of glucose transporter type 4 (GLUT4) without affecting the Akt pathway.

128 eased mRNA expression of glucose transporter type 4 (GLUT4), lipoprotein lipase (LpL), peroxisome pro

129 -stimulated recycling of glucose transporter type 4 (Glut4), which is required for glucose homeostasi

130 pproximately 2-fold) and glucose transporter type 4 (GLUT4; approximately 1.3-fold) levels in WAT in

131 The glucose transporter type-4 (GLUT4) is primarily responsible for the insulin-

132 served residues and motifs characteristic of type 4 group A pilins.

133 3)-D-Asn-L-Lys(3) bridges replacing the wild-type 4-->3 D-Ala(4)-D-Asn-L-Lys(3) bridges.

134 at nuclear NAC1 binds to histone deacetylase type 4 (HDAC4), hindering phosphorylation of HDAC4 at Se

135 sherbst (weh(Tp85c-/-)) and in patients with type 4 hemochromatosis.

136 encodes 17beta-hydroxysteroid dehydrogenase type 4 (HSD17B4), also known as D-bifunctional protein (

137 lent, followed by type 3, type 2, type 5 and type 4 in that order.

138 shunts (type 3) in one, portovenous shunts (type 4) in three, and both arteriovenous and portovenous

139 4A mutation is also associated with dystonia type 4, in which magnetic resonance images of the brain

140 We administered a phosphodiesterase type 4 inhibitor and dibutyryl cyclic adenosine monophos

141 active, potent, selective phosphodiesterase type 4 inhibitor, which in vitro can affect cells though

142 ing p16 inhibitor of cyclin-dependent kinase type 4 (INK4a) in individuals with melanoma using a popu

143 Pure hereditary spastic paraplegia (SPG) type 4 is the most common form of autosomal dominant her

144 uman HEK293T cell lines, but zebrafish CRY4 (type 4) is not.

145 The autosomal dominant form of the disease, type 4, is due to mutations in the SLC40A1 gene, which e

146 patterns, 10 of which were found among phage type 4 isolates.

147 A for the predominant type 2 isozyme and the type 4 isozyme were detected in northern analysis.

148 rboxy-terminal domain of apo(a) containing 6 type-4 kringles (types 5 to 10), kringle V, and the prot

149 and thereby cause Leber congenital amaurosis type 4 (LCA4), a severe form of childhood blindness.

150 l cardiac arrhythmia initially classified as type 4 long QT syndrome.

151 d cardiac arrhythmia, initially described as type 4 long QT syndrome.

152 mbrane adapters, causes dominantly inherited type 4 long-QT cardiac arrhythmia in humans.

153 Mutations in the ankyrin-B gene (ANK2) cause type 4 long-QT syndrome and have been described in kindr

154 lipid phosphate phosphatase-related protein type 4 (LPPR4) (OR, 2.30; P = 4.82 x 10(-6)) and solute

155 a relatively selective muscarinic type 1 and type 4 (M(1) and M(4)) receptor agonist, to determine if

156 cosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase (MT4-MMP, MMP-17) becaus

157 y]), glycolysis (monocarboxylate transporter type 4 [MCT-4]), and angiogenesis (vascular endothelial

158 nnabarinic acid acts as a partial agonist of type 4 metabotropic glutamate (mGlu4) receptors, with no

159 plus T1r3,as well as a truncated form of the type 4 metabotropic glutamate receptor (taste-mGluR4),as

160 Herein we study the ability of type 4 metabotropic glutamate receptors (mGlu4) to regul

161 vior, and it is proposed that type 1 MLN and type 4 MLN represent the absolute states and types 2 and

162 and conjugate horizontal jerk MLN waveforms (type 4 MLN).

163 % of the subjects exhibited either type 3 or type 4 MLN, both of which conform with previous classic

164 e interactions between ADAMTS-4 and membrane type 4 MMP (MT4-MMP), protein lysates purified from stim

165 Human membrane type 4 MMP CD (MT4-MMPCD) protein, expressed as inclusio

166 d increased expression of MMP-9 and membrane type 4-MMP as compared with LNCaP and DU-145.

167 d with maturity onset diabetes of the young, type 4 (MODY4) and type 2 diabetes.

168 ula (34%) while Grade 5 was the least common type (4%).MRI showed a high sensitivity of 93.7% and pos

169 BRAF mutation, positive for KRAS mutation); type 4 (MSS or MSI-low, non-CIMP, negative for mutations

170 The type-4 MTs (MT4a and MT4b) conferred greater Zn toleranc

171 f sequence at the metacyclic variant antigen type 4 (MVAT) vsg expression site (ES) revealed an ES-as

172 In many tissues, type 4 NADPH oxidase is induced upon ischemia or hypoxia

173 astin staining, and C-X-C chemokine receptor type 4, nuclear factor kappa beta, and tartrate-resistan

174 ic mutations in SLC45A2, associated with OCA type 4 (OCA-4), and G6PC3, associated with neutropenia.

175 ovirus, with 90% identity in most adenovirus type 4 open reading frames that have been sequenced.

176 ell-derived 1 alpha receptor (C-X-C receptor type 4 or CXCR4) using AMD3100 prevented the polarizatio

177 fferent from that seen in variant CJD brain (type 4) or in brain from other CJD subtypes (types 1-3).

178 ensin II on other receptors (eg, angiotensin type 4) or lower degradation of growth-inhibitory kinins

179 7-fold greater than the K(d) found with wild-type 4-OT (0.6 mM).

180 f all of the Arg Nepsilon resonances in wild-type 4-OT and in the R11A and R39Q mutants were found to

181 We demonstrate that the unfolding of wild-type 4-OT in 50 mM phosphate buffers containing 6 M GuHC

182 The binding of cis,cis-muconate to wild-type 4-OT upshifts Arg-11 Nepsilon (by 0.05 ppm) and dow

183 ced equilibrium unfolding properties of wild-type 4-OT using catalytic activity measurements and usin

184 substrate increased in comparison with wild-type 4-OT, indicating the importance of Arg-11 in proper

185 erstrand NOEs and one turn NOE found in wild-type 4-OT.

186 K(a) = 6.5 +/- 0.2) agreed with that of wild-type 4-OT.

187 Drs2p is a resident type 4 P-type ATPase (P4-ATPase) and potential phospholi

188 PFxD motif, which signals for endocytosis, a Type 4 P-Type ATPase was identified and named DnfA.

189 egated within the Spitzenkorper from another Type 4 P-type ATPase, DnfB.

190 Type 4 P-type ATPases (P(4)-ATPases) catalyze phospholip

191 inating enzymes, peptidyl arginine deiminase type 4 (PAD-4), is genetically associated with developme

192 ated proteins and peptidylarginine deiminase type 4 (PAD-4).

193 The type 4 PDE inhibitor rolipram but not the type 1 inhibit

194 cterium tuberculosis-infected mice receiving type 4 PDE-Is (rolipram and cilomilast) and the impact o

195 Type 4 PDE-Is may increase the severity of tuberculosis

196 The type 4 PDE-Is rolipram and cilomilast accelerated the ti

197 Inhibitors of phosphodiesterase type 4 (PDE4) act by increasing intracellular concentrat

198 t years, cyclic nucleotide phosphodiesterase type 4 (PDE4) has aroused scientific attention as a suit

199 show that atropine acts as an allosteric PDE type 4 (PDE4) inhibitor.

200 Cyclic nucleotide phosphodiesterase type 4 (PDE4) is a cAMP-specific phosphodiesterase that

201 Phosphodiesterase type 4 (PDE4) is a family of enzymes that selectively de

202 Inhibition of type 4 phosphodiesterase (PDE4) and elevation of cyclic

203 Type 4 phosphodiesterase (PDE4) inhibitors are emerging

204 The type 4 phosphodiesterase (PDE4) is the predominant PDE i

205 MP cascade and requires participation of the type 4 phosphodiesterase (PDE4), a new role for phosphod

206 Purified recombinant human type 4 phosphodiesterase B2B (HSPDE4B2B) exists in both

207 monophosphate (cAMP) signaling by increasing type 4 phosphodiesterase catabolism of cAMP when cAMP co

208 Pretreatment with the type 4 phosphodiesterase inhibitor, rolipram, abolished

209 Infusion of the type 4 phosphodiesterase inhibitor, rolipram, prevented

210 MP, cAMP-dependent protein kinase (PKA), and type 4 phosphodiesterase may be involved in attenuating

211 odulator of inflammatory cell responses, and type 4 phosphodiesterases (PDE4) are important regulator

212 Type 4 phosphodiesterases (PDE4) are key cAMP-hydrolyzin

213 Splicing variants of type 4 phosphodiesterases (PDE4) are regulated by phosph

214 r, pretreatment with selective inhibitors of type 4 phosphodiesterases (PDE4), protein kinase A (PKA)

215 ydroxydopamine (6-OHDA) on the expression of type 4 phosphodiesterases (PDE4).

216 Four genes code for type 4 phosphodiesterases (PDE4s), enzymes critical for

217 EHEC) O157:H7 produces long bundles of polar type 4 pili (T4P) called HCP (for hemorrhagic coli pili)

218 bacteria exhibit surface motility powered by type 4 pili (T4P).

219 exhibited twitching motility, which requires type 4 pili (Tfp), and electron microscopy revealed that

220 o gene products required for the assembly of type 4 pili and for the secretion of certain proteins in

221 saccharide, mannose-sensitive haemagglutinin type 4 pili and polar (but not lateral) flagella.

222 This leads to the conclusion that type 4 pili and the DNA translocator are distinct system

223 Type 4 pili are found on the surface of a variety of gra

224 in complete contrast to the situation in the type 4 pili system homologs, in the T2SS, the major prot

225 tion of how DifA receives input signals from type 4 pili without a prominent periplasmic domain.

226 Bacterial type 2 secretion systems (T2SS), type 4 pili, and archaeal flagella assemble fibres from

227 long, thin fibers, similar in appearance to type 4 pili.

228 for S motility is generated by retraction of type 4 pili.

229 affecting the export and assembly of surface type 4 pili.

230 El Tor biotype is a member of the family of type 4 pili.

231 ent on the extension and retraction of polar type 4 pili.

232 oteins to those required for the assembly of type-4 pili and for type-2 protein secretion is discusse

233 is 46% identical to a Pseudomonas aeruginosa type 4 pilin over its entire length and has all the cons

234 pseudopilins that are similar in fold to the type 4 pilins.

235 acid sequence of this protein was typical of type 4 pilins.

236 Biogenesis of this type 4 pilus (Tfp) requires a number of structural compo

237 Due to similarities to the type 4 pilus and the type 2 secretion system pseudopilus

238 rotoxigenic Escherichia coli produces a long type 4 pilus called Longus.

239 Toxin-coregulated pilus (TCP), a type 4 pilus expressed by V. cholerae, is a cholera viru

240 equired for a variety of functions including type 4 pilus formation, toxin and other enzyme secretion

241 larensis Schu S4 strain was found to contain type 4 pilus genes, and we confirmed that these genes ar

242 gement unique among previously characterized type 4 pilus loci.

243 r biotype mutants, surface expression of the type 4 pilus responsible for mannose-sensitive haemagglu

244 ndent on orthologues of Type 2 secretion and Type 4 pilus system proteins.

245 The toxin-co-regulated pilus (TCP), a type 4 pilus that is expressed by epidemic strains of Vi

246 quorum-sensing systems are also required for type 4 pilus-dependent twitching motility and infection

247 s with N-terminal sequence motifs typical of type 4 pre-pilins (ComGC, GD, GE and GG) are processed b

248 Follicle development arrests at the type 4 preantral stage and although oocytes commence gro

249 t is cleaved off by a cognate membrane-bound type 4 prepilin peptidase (TFPP) during the process of s

250 For example, type 4 prepilin peptidase may contribute to bacterial pa

251 80% homology with the Vibrio vulnificus VvpD type 4 prepilin peptidase required for pilus assembly an

252 Accordingly, the V. cholerae type 4 prepilin peptidase required for pilus assembly an

253 f the family include preflagellin peptidase, type 4 prepilin peptidase, presenilin and signal peptide

254 Type 4 prepilins or prepilin-like-proteins are secreted

255 ), Type 3 units (unknown function; n = 4) or Type 4 (presumed sympathetics; n = 23) units.

256 Spastic paraplegia types 4 (prevalence, 0.91 per 100,000 population), 3 (pr

257 ven regions of the serovar Enteritidis phage type 4 (PT4) chromosome (sequenced at the Sanger Center)

258 an protein tyrosine phosphatase non-receptor type 4 (PTPN4) prevents cell death induction in neurobla

259 tionship between central 5-HT tonus and 5-HT type 4 receptor (5-HT4R) density, suggesting that 5-HT4R

260 cells were transfected with the melanocortin type 4 receptor (MC4-R), but not the type 3 receptor.

261 Similarly, introduction of wild-type 4-repeat tau (tau-4R) into wild-type animals trigge

262 suppressing regulator of G protein signaling type 4 (RGS4) activity, and blocked D1 dopamine receptor

263 the regulator of G-protein-signaling protein type 4 (RGS4) is differentially regulated in the locus c

264 radation of regulator of G protein signaling type 4 (RGS4), thus relieving the repression of the Gbet

265 hitherto unknown effects of resistant starch type 4 (RS4) enriched diet on gut microbiota composition

266 One cancer-linked locus is the cag type 4 secretion system (cagT4SS), which translocates an

267 We also demonstrate that the Coxiella type 4 secretion system (T4SS) is critical for the forma

268 We also found that heat-killed NMII and type 4 secretion system (T4SS) mutant NMII were unable t

269 s' disease, encodes two virulence-associated type 4 secretion systems (T4SSs), the Dot/Icm type 4B (T

270 stromal-derived factor-1/chemokine receptor type 4 signaling revealed greater functional dependence

271 t and highly selective binding to human SRIF type 4 (sst(4)) receptors.

272 C. sakazakii sequence type 4 (ST4) was the predominant sequence type of cerebr

273 expressing a family 1 PspA (WU2), a capsular type 4 strain expressing a family 2 PspA (TIGR4), and ge

274 6A strain able to inhibit the growth of the type 4 strain, TIGR4, in vitro.

275 er difficulty in protecting against capsular type 4 strains resulted from differences in their PspAs

276 is less efficacious against several capsular type 4 strains than against strains of capsular types 3,

277 he difficulty in protecting against capsular type 4 strains was eliminated when mice were immunized w

278 esins, pili or fimbriae, which belong to the type-4 structural group of pili also found on other bact

279 adrenergic receptor-C-X-C chemokine receptor type 4 structure as a template, we created a homology mo

280 The effect of NanA was shown using both type 4 (TIGR4) and type 6A clinical isolates.

281 ll intestine by Vibrio cholerae requires the type 4 toxin co-regulated pilus (TCP).

282 f the transient receptor potential vanilloid type 4 (TRPV4) channel is associated with edema formatio

283 le of transient receptor potential vanilloid type-4 (TRPV4) in itch is unknown.

284 Compared with participants with type 4 tumors (the most predominant), participants with

285 , Npy5r, and Npy6r, the genes encoding mouse type 4, type 5, and type 6 members of the neuropeptide Y

286 Among non-nociceptive fibres, all Type 4 units exhibited long-lasting supernormality indep

287 For phosphodiesterase type 4 variant 4 (PDE4D4), an enzyme responsible for cyc

288 l-derived factor-1, C-X-C chemokine receptor type 4, vascular endothelial growth factor, and endothel

289 on the backbone of a nonneuroinvasive dengue type 4 virus (DEN4), has been identified as a promising

290 and all other sequences derived from dengue type 4 virus (DEN4).

291 ivirus for the corresponding genes of dengue type 4 virus (DEN4).

292 Fab monoclonal antibodies to dengue type 4 virus (DENV-4) were recovered by repertoire cloni

293 irus or vaccinia virus expressing the dengue type 4 virus NS3 protein were cross-reactive with dengue

294 in were cross-reactive with dengue type 2 or type 4 virus, while broadly serotype-cross-reactive CTL

295 The effects of sulfation type (4- vs. 6-sulfation), sulfation pattern (statistica

296 ation are classified as Waardenburg syndrome type 4 (Waardenburg-Shah, WS4).

297 bitor of the cAMP-specific phosphodiesterase type 4, was administered to activate the cAMP cascade, a

298 ce with congenital generalized lipodystrophy type 4, whereas both rMAT and cMAT are preserved in mice

299 ones: 16S type 5 with MenA subgroup III, 16S type 4 with the MenB electrophoretic type 5 (ET-5) compl

300 Clinical outcomes, stratified by stent type, years after PCI were determined from the Vete