ライフサイエンスコーパス: type I keratin

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1 n K16 are shorter than those formed by other type I keratins.

2 The type I keratins 14 (K14) and 16 (K16) are distinct in th

3 We previously hypothesized that the type I keratin 16 (K16) plays a role in the process of k

4 e existence of the mouse equivalent of human type I keratin 16 (K16).

5 Mutations in the type I keratin 16 (Krt16) and its partner type II kerati

6 study, we analyzed the distribution of mouse type I keratin 16 during skin morphogenesis, in the adul

7 The type II keratin 6 and type I keratins 16 and 17 are induced well before cell m

8 The type I keratin 17 (K17) shows a peculiar localization in

9 Onset of type I keratin 17 (K17) synthesis marks the adoption of

10 Inactivating the type I keratin 17 gene (mK17) causes severe but reversib

11 in protein that bears high similarity to the type I keratins and displays a unique expression profile

12 Our results indicate that type I keratins are targets of apoptosis-activated caspa

13 keratin gene cluster on 12q; and K12 to the type-I keratin cluster on 17q using radiation hybrids.

14 been removed, or copolymers of K5 and K19, a type I keratin featuring a short tail domain.

15 8 and D17S957, a region known to contain the type I keratin gene cluster and other genes expressed in

16 ocated at the beginning of the rod domain of type I keratins, is particularly sensitive to amino acid

17 eton and developed massive aggregates of the type I keratin, K10.

18 tate of VEMDA, a consensus sequence found in type I keratins K12-17 with similar but not identical se

19 We show here that yet another related type I keratin, K17, forms stable heterotetramers with a

20 Type I keratins K18 and K19 undergo caspase-mediated deg

21 ssion of the type-II keratin K8 up-regulated type-I keratins K18, K19, and K20 and generated K19/K20-

22 tion that maps to chromosome 11 close to the type I keratin locus.

23 Several K14 (another type I keratin) mutations within the caspase cleavage mo

24 understood, caspase-mediated degradation of type I keratins occurs during apoptosis and the proteaso

25 stream from mK17 is functional and encodes a type I keratin protein highly analogous to mK17.

26 bait in a yeast two-hybrid screen pulls out type I keratin sequences from a skin cDNA library.

27 9 regulation or function, and the only other type I keratin that has been studied in terms of regulat

28 perties that suggest different regulation of type I keratins within the same cells.

29 Keratin 15 (K15) is a type I keratin without a defined type II partner whose e

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