ライフサイエンスコーパス: type IV

1 otor neuron loss and normal life expectancy (type IV).

2 en type VI and, to a lesser extent, collagen type IV.

3 e types consisted predominantly of type I or type IV.

4 Type I: 6, Type 2: 6, Type III: 6, Type IV: 11, Type V: 4.

5 Here we report five children with a form of type IV 3-MGA-uria characterized by cataracts, severe ps

6 , with type III (29.6%), type II (14.5%) and type IV (5.7%).

7 Mutations in TRPML1 lead to mucolipidosis type IV, a severe lysosomal storage disorder.

8 robiota (Nugent score 4-10), community state types IV-A and IV-B, and STIs will likely increase trans

9 n of SidJ is dependent on the chaperone-like type IV adaptors IcmS/IcmW.

10 f BL proteins-laminin, fibronectin, collagen type IV, agrin, and perlecan-on adhesion and TEER was as

11 on of fumarate hydratase (FH), and collagen, type IV, alpha 5 and collagen, type IV, alpha 6 (COL4A5-

12 and collagen, type IV, alpha 5 and collagen, type IV, alpha 6 (COL4A5-COL4A6) deletions.

13 Collagen type IV alpha1 (COL4A1) and alpha2 (COL4A2) form heterot

14 rate, mesangial cell expansion, and collagen type IV and transforming growth factor-beta expression w

15 2015 presented with a greater percentage of Type IV and Type V cases.

16 51, and LN229 induces expression of collagen types IV and VI and the collagen crosslinking enzyme lys

17 The alpha(1,3)-fucosyltransferases, types IV and VII (FUT4 and FUT7, respectively), are requ

18 I), Porphyromonas and Peptoniphilus species (type IV), and Propionibacterium acnes (type V).

19 ive lysosomal storage disorder mucolipidosis type IV, and a gain-of-function mutation (Ala419Pro) in

20 ction system using purified collagen type I, type IV, and nonglycosylated, commercially available rec

21 esent in congenital dyserythropoietic anemia type IV as a result of dominant mutations in the second

22 tion-dependent restriction enzymes was named Type IV, as distinct from the familiar modification-bloc

23 operons and function via a non-interacting (Type IV) bacteriostatic TA mechanism.

24 ically consisting of mixtures of type II and type IV beta-turns.

25 nts in type II bone and good-to-excellent in type IV bone; interobserver reliability was evaluated as

26 Calcium/calmodulin-dependent protein kinase type IV (CaMKIV) is a key sensory/effector in excitatory

27 t that the phenotypic manifestations of FFDD Type IV can be non-penetrant or underascertained.

28 ildren vs adults (79.7% vs 64.9%; P = .003); type IV CCs predominated in the adult population (23.9%

29 re in changing blue-green environments using type IV chromatic acclimation (CA4).

30 s revealed that 8 known genotypes (D, Peru8, type IV, CM1, EbpC, PigEBITS5, O, and EbpA) and 7 new ge

31 self-antigens fibronectin (FN) and collagen type-IV (Col-IV).

32 elf-epitope derived from the alpha3 chain of type IV collagen (alpha3135-145).

33 ncollagenous domain 1 of the alpha3-chain of type IV collagen (alpha3IV-NC1).

34 noncollagenous domain of the alpha3 chain of type IV collagen (alpha3NC1) developed albuminuria assoc

35 gh previous work has shown that VWF can bind type IV collagen (collagen 4), little characterization o

36 lymeric networks - one of laminin and one of type IV collagen (Figure 1, bottom).

37 of the basement membrane components, alpha1-type IV collagen and alpha2-type IV collagen, gamma1-lam

38 erium tuberculosis (Mtb) causes breakdown of type IV collagen and decreases tight junction protein (T

39 ron microscope analysis, the distribution of type IV collagen and effects of fibrosis on myocyte memb

40 Compositionally, our results identify type IV collagen as the first macromolecular biomarker o

41 inverted polarized cysts, with no laminin or type IV collagen assembly at cell/extracellular matrix c

42 associated with mutations in genes encoding type IV collagen chains present in the glomerular baseme

43 with hearing loss, results from mutations in type IV collagen COL4A3, COL4A4, or COL4A5 genes.

44 Without reduction, type IV collagen contained macromolecular alpha-chains o

45 Thus, prolyl 3-hydroxylation of type IV collagen has an important function preventing ma

46 We now show that type IV collagen is a component within the morphological

47 Type IV collagen is a major and crucial component of bas

48 ion and cell-matrix adhesion by showing that type IV collagen is essential for inter-adipocyte adhesi

49 Although type IV collagen is heavily glycosylated, the influence

50 l fibrillation and that CLICs and structural type IV collagen may interact on each other to promote t

51 In contrast, loss of type IV collagen may represent a biochemical rationale f

52 eraction between GPVI and non-3-hydroxylated type IV collagen might also play a role in the progressi

53 with type VII collagen, we hypothesized that type IV collagen should also be localized to the DEJ in

54 sibility of extracellular deglycosylation of type IV collagen was investigated, but no beta-galactosi

55 focal microscopy revealed that immunostained type IV collagen was restricted to the 5- to 10-microm-w

56 ellular channel (CLIC) 1, 4, 5 and a rise in type IV collagen were revealed.

57 interaction of non-3-hydroxylated embryonic type IV collagen with the maternal platelet-specific gly

58 d cornea (type I collagen) and lens capsule (type IV collagen) were dissected from mouse eyes, and mu

59 Type IV collagen, a major constituent of BMs, is critica

60 noncollagenous domain of the alpha3 chain of type IV collagen, alpha3(IV)NC1, but critical early T ce

61 xtracellular matrix proteins fibronectin and type IV collagen, and loss of podocyte markers WT1 and s

62 ith extracellular matrix components, such as type IV collagen, and with the innate immune protein ser

63 ed the possible interaction between CLIC and type IV collagen, confirmed by protein structure predict

64 mponents, alpha1-type IV collagen and alpha2-type IV collagen, gamma1-laminin and beta2-laminin, were

65 In type IV collagen, these sites are normally 3-hydroxylate

66 ) by uncontrolled buildup of ECM, especially type IV collagen, which progressively occludes the capil

67 f endothelial cells leaving behind avascular type IV collagen-positive empty sleeves with remaining p

68 rface also showed positive stain results for type IV collagen.

69 in pericyte-conditioned medium and purified type IV collagen.

70 icroscopy to show positive stain results for type IV collagen.

71 transwell cell culture inserts coated with a type-IV collagen membrane on which an IOL (one-piece Tec

72 urthermore, the basement membrane-associated type IV collagens regulate ISC self-renewal by confining

73 Type IV coupling protein (T4CP) is a hexameric ATPase th

74 es, 9 known (PtEbIX, O, D, CM1, EbpA, Peru8, type IV, EbpC, and PigEBITS5) and 9 new (CD1 to CD9), we

75 ere we test the ability of 200 type III and type IV effector proteins from six Gram-negative bacteri

76 on these proteins, the resurgent interest in Type IV enzymes as tools for epigenetic research and the

77 Type IV enzymes recognize modified DNA with low sequence

78 Technical advances allow use of Type IV enzymes to study epigenetic mechanisms in mammal

79 Sequencing of four additional, unrelated Type IV FFDD patients and eight Type II or III TWIST2-ne

80 One of the most well-studied type IV filaments is the gonococcal type IV pilus (GC-T4

81 A type IV functional response (i.e. dome-shaped relationsh

82 We report a type IV functional response observed in heifers grazing

83 The type IV functional response resulted from changes in bit

84 Whole genome sequencing of 70 type IV GBS and subsequent phylogenetic analysis elucida

85 Glycogen storage disease type IV (GSD IV) is a rare autosomal recessive disorder

86 eneous early-onset glycogen storage disorder type IV (GSDIV) or the late-onset adult polyglucosan bod

87 ed gene, 17beta-hydroxysteroid dehydrogenase type IV (HSD17B4), coding for a steroidogenic enzyme tha

88 nsistent with a delayed-type immune-mediated type IV hypersensitivity in a 90-day NHP regulatory toxi

89 We previously observed a cutaneous type IV immune response in nonhuman primates (NHP) with

90 Viral mRNA sequences with a type IV IRES are able to initiate translation without an

91 Focal facial dermal dysplasia (FFDD) Type IV is a rare syndrome characterized by facial lesio

92 Vascular Ehlers-Danlos syndrome (EDS) type IV is the most severe form of EDS.

93 s classified into five groups, of which one, type IV, is genetically heterogeneous.

94 tive splicing, and association of brain NRG1 type IV isoform expression with the schizophrenia-risk p

95 etic analysis elucidated the localization of type IV isolates in a SNP-based phylogenetic tree and su

96 including NPC1, mild cases of mucolipidosis type IV (ML4) (TRPML1-F408), Niemann-Pick type A (NPA) a

97 Mucolipidosis type IV (MLIV) is a lysosomal storage disease characteri

98 Mucolipidosis type IV (MLIV) is an autosomal recessive lysosomal stora

99 RPML1 has been associated with mucolipidosis type IV (MLIV), while no disease phenotype has been link

100 t TRPML1 (ML1), a protein that is mutated in type IV mucolipidosis (ML-IV), is a tubulovesicular chan

101 f-function mutations are the direct cause of type IV mucolipidosis, an autosomal recessive lysosomal

102 Phospholipid flippases in the type IV P-type ATPase (P4-ATPases) family establish memb

103 aryotic organisms typically express multiple type IV P-type ATPases (P4-ATPases), which establish pla

104 screening and directed mutagenesis with the type IV P-type ATPases Dnf1 and Drs2 from budding yeast,

105 ts into the molecular basis of mucolipidosis type IV pathogenesis.

106 ive FFDD patients revealed that three of the Type IV patients were homozygous for the duplication, wh

107 etion systems and are linked to extrusion of type IV pili (T4P) and to DNA uptake.

108 Type IV pili (T4P) are among the key virulence factors u

109 Type IV pili (T4P) are filamentous appendages found on m

110 Type IV pili (T4P) are ubiquitous and versatile bacteria

111 Type IV pili (T4P) are ubiquitous bacterial cell surface

112 Type IV pili (T4P) are very thin protein filaments that

113 ansduction systems that regulate motility by type IV pili (T4P) can be markedly more complex than rel

114 Type IV pili (T4P) contain hundreds of major subunits, b

115 Neisseria meningitidis use Type IV pili (T4P) to adhere to endothelial cells and br

116 ic autotransporter adhesins, O antigens, and type IV pili (T4P).

117 eins, toxins, or filamentous phages; extrude type IV pili (T4P); or take up DNA.

118 tility, and appendages known as flagella and type IV pili (TFP) are known to confer such motility.

119 Type IV pili (TFP) function as mechanosensors to trigger

120 oups through the extension and retraction of type IV pili (TFP) on solid surfaces, which requires bot

121 oluble form of PilA [the majority subunit of Type IV pili (Tfp) produced by NTHI], mediated gradual '

122 cial ("S")-motility mechanism is mediated by type IV pili (TFP), linear actuator appendages that prop

123 inosa move across surfaces by using multiple Type IV Pili (TFP), motorized appendages capable of forc

124 Type IV pili (Tfp), which are key virulence factors in m

125 Type IV pili (Tfp), which have been studied extensively

126 recently emerged as a model for the study of type IV pili (Tfp)-exceptionally widespread and importan

127 lified by a positive feedback that increases type IV pili activity, thereby promoting long-term surfa

128 e factors utilized by these bacteria are the type IV pili and a protein O-glycosylation system.

129 terium Synechocystis sp. PCC 6803 moves with Type IV pili and measures light intensity and color with

130 s powered by the extension and retraction of type IV pili and requires the presence of exopolysacchar

131 The hair-like cell appendages denoted as type IV pili are crucial for biofilm formation in divers

132 Type IV pili are extracellular polymers of the major pil

133 Type IV pili are important for microcolony formation, bi

134 Type IV pili are important virulence factors for many pa

135 Type IV pili are important virulence factors on the surf

136 Type IV pili are long fibers that are assembled by polym

137 Type IV pili are long, protein filaments built from a re

138 Type IV pili are produced by many pathogenic Gram-negati

139 at the envelope protein PilY1 and functional type IV pili are required mechanosensory elements.

140 Type IV pili are ubiquitous bacterial motors that power

141 ovide a starting point for understanding how type IV pili can mediate secretion of virulence factors

142 In many bacteria and archaea, type IV pili facilitate surface adhesion, the initial st

143 of a lytic Pf4 bacteriophage, which may use type IV pili for infection.

144 demonstrate that P. aeruginosa not only uses type IV pili for surface-specific twitching motility, bu

145 We show that PilJ is incorporated into Type IV pili in C. difficile and present a model in whic

146 unction of the structurally related archaeal type IV pili is unknown.

147 ype IV pili, and offer insights into how the Type IV pili of C. difficile may assemble and function.

148 a and mannose-sensitive hemagglutinin (MSHA) type IV pili synergistically to switch between two compl

149 ransduction mechanism requires attachment of type IV pili to a solid surface, followed by pilus retra

150 Bacteria such as Pseudomonas aeruginosa use type IV pili to move across surfaces.

151 ry pathogen Streptococcus pneumoniae deploys type IV pili to take up DNA during transformation.

152 escales using the mechanical activity of its type IV pili, a major surface adhesin.

153 in, PilJ, demonstrate its incorporation into Type IV pili, and offer insights into how the Type IV pi

154 es a variety of virulence factors, including type IV pili, bacterial extracellular appendages often e

155 re required for assembly of their respective Type IV pili, CFA/III and Longus.

156 flagella, and twitching motility powered by Type IV pili, little is known about gliding motility.

157 multiple long and flexible filaments, called type IV pili, that extend from the cell body, attach to

158 single flagellum and one or two clusters of type IV pili, to the cell poles.

159 Movement depends on Type IV pili, which are extended, adhere to the substrat

160 s on surfaces as structured swarms utilizing type IV pili-dependent social (S) motility.

161 trast to their biofilm-promoting function in type IV pili-producing heterotrophic bacteria.

162 ation between cyanobacteria and well-studied type IV pili-producing heterotrophic bacteria.

163 ish it from both the bacterial flagellum and type IV pili.

164 but the directional motive force comes from Type IV pili.

165 intracellular photoreceptors and mediated by Type IV pili.

166 induced conformational changes in stretched type IV pili.

167 including Clostridium difficile, to produce Type IV pili.

168 ility of the bacterium to express functional type IV pili.

169 or export of substrates and/or extrusion of type IV pili.

170 esence of the ctpABCDEFGHI genes (cluster of type IV pili; Atu0216 to Atu0224), homologous to tad-typ

171 in (RTX) toxins, RHS proteins, adhesins, and type IV pili] that likely mediate cell-cell interactions

172 is dependent on extension and retraction of Type-IV pili (T4P) and production of extracellular polys

173 l structure of PilEDelta1-28 shows a typical type IV pilin fold, demonstrating how it may be incorpor

174 nii subsets produce morphologically distinct type IV pilin glycoproteins.

175 our results provide the first structure of a type IV pilin protein involved in the formation of compe

176 A, pilD, and mshA genes, all of which encode type IV pilin proteins that aid in attachment to surface

177 te the remarkable structural diversity among type IV pilin proteins.

178 encode two O-OTases, one devoted uniquely to type IV pilin, and the other one responsible for glycosy

179 ree-dimensional structure of a Gram-positive Type IV pilin, PilJ, demonstrate its incorporation into

180 omolog of the N-terminal domain of bacterial type IV pilin, showing once again how proteins can be re

181 a highly flexible and structurally divergent type IV pilin.

182 nas aeruginosa express one of five different type IV pilins (T4P) (5) , two of which are glycosylated

183 fic surface structures on the bacterium, the type IV pilins PilA and MshA, in adherence to diatom-der

184 features of ecological interest include two type IV pilins, multiple extracytoplasmic function-sigma

185 hus motility reversals but is independent of type IV pilus "S motility." The inheritance of opposing

186 -studied type IV filaments is the gonococcal type IV pilus (GC-T4P) from Neisseria gonorrhoeae, the c

187 It is known that S motility requires the type IV pilus (T4P) and the exopolysaccharide (EPS) to f

188 an important model system for the studies of Type IV pilus (T4P) because it is motile by social (S) m

189 fy the inner membrane proteins essential for type IV pilus (T4P) expression in Pseudomonas aeruginosa

190 The bacterial type IV pilus (T4P) is a versatile molecular machine wit

191 ork, we investigated the role of the primary type IV pilus (T4P) locus in c-di-GMP-dependent cell agg

192 ce motility powered by the retraction of the type IV pilus (T4P).

193 Previously, we have demonstrated that the type IV pilus (Tfp) of P. aeruginosa mediates resistance

194 Type IV pilus assembly involves a conserved group of pro

195 The protein complex responsible for type IV pilus assembly is homologous with the type II pr

196 pendent on the presence of components of the type IV pilus biogenesis apparatus for secretion have be

197 ting that these proteins are secreted by the type IV pilus biogenesis system.

198 cts several processes, including phototaxis, type IV pilus biosynthesis, photosystem II levels, biofi

199 with bacterial type II secretion system and type IV pilus formation were shown to specifically bind

200 ner membrane proteins that are essential for type IV pilus formation.

201 through the ComE pore through which the NTHI type IV pilus is expressed.

202 In this study, we used the type IV pilus of Neisseria gonorrhoeae to test whether v

203 n genes are located directly downstream of a type IV pilus operon in strongly cellulolytic members of

204 -gene mannose-sensitive hemagglutinin (MSHA) type IV pilus operon), had reduced infectivity of A. cyt

205 The toxin-coregulated pilus (TCP), a type IV pilus required for V. cholerae pathogenesis, is

206 he velocity-force relation of DNA uptake and type IV pilus retraction, we can exclude pilus retractio

207 NA from the environment, is supported by the type IV pilus system in most species.

208 nd Vibrio cholerae are among the simplest of Type IV pilus systems and possess only a single minor pi

209 nderstanding filament growth in more complex Type IV pilus systems as well as the related Type II sec

210 The Type IV pilus systems of enterotoxigenic Escherichia col

211 icles, the type II secretion system, and the type IV pilus, were dispensable for YbcL(UTI) release fr

212 bit flagellum-driven motility and upregulate type IV pilus-dependent twitching motility of P. aerugin

213 e identified a putative chemotaxis operon, a type IV pilus-encoding cluster and a region encoding put

214 that Hps and Pil proteins compose the JPC, a type IV pilus-like nanomotor that drives motility and po

215 evidence implies that the JPC is a modified type IV pilus-like structure encoded for in part by gene

216 n systems, indicating that this is unique to type IV pilus-mediated secretion.

217 For twitching, powered by type-IV pilus retraction, we find that individual cells

218 Type IV REases tend to target modified DNA sites, and E.

219 identified in patients with Bartter syndrome type IV, reduce barttin palmitoylation and CLC-K/barttin

220 Therefore, a type IV response of intake rate not directly related to

221 The first reported Type IV restriction endonuclease (REase) GmrSD consists

222 ated adenine Recognition and Restriction), a Type IV restriction endonuclease (REase), as instigator

223 ia may have developed modification-dependent type IV restriction enzymes to defend the cell from T4-l

224 Thus, FFDD Type IV results from the loss of function mutations in C

225 Type IV secretion (T4S) systems are large dynamic nanoma

226 Type IV secretion (T4S) systems are versatile bacterial

227 trolled by RpfC to include genes involved in type IV secretion and chemotaxis.

228 A type IV secretion effector of E. chaffeensis blocks mito

229 not lose expression or translocation of six type IV secretion effectors (e.g., SidM) that are well k

230 To better understand the mechanism of type IV secretion in N. gonorrhoeae, we examined the exp

231 acter pylori (Hp) strains that carry the cag type IV secretion system (cag-T4SS) to inject the cytoto

232 n host cell interactions through the Icm/Dot type IV secretion system (T4SS) and approximately 300 di

233 The Dot/Icm type IV secretion system (T4SS) of Legionella pneumophil

234 kinases that are translocated by the Dot/Icm type IV secretion system (T4SS) of several Legionella pn

235 he cag pathogenicity island, which encodes a type IV secretion system (T4SS) that injects the CagA on

236 ic cag pathogenicity island, which encodes a type IV secretion system (T4SS) that translocates a pro-

237 The pathogen uses a Dot/Icm type IV secretion system (T4SS) to deliver effector prot

238 intracellular bacterial pathogens that use a type IV secretion system (T4SS) to escape host defenses

239 olar macrophages, C. burnetii uses a Dot/Icm type IV secretion system (T4SS) to generate a phagolysos

240 Neisseria gonorrhoeae uses a type IV secretion system (T4SS) to secrete chromosomal D

241 ionnaires' disease, uses its dot/icm-encoded type IV secretion system (T4SS) to translocate effector

242 permissive host cells by employing a Dot/Icm type IV secretion system (T4SS) to translocate effector

243 otein VirB10 of the Agrobacterium VirB/VirD4 type IV secretion system (T4SS) undergoes a structural t

244 Using the Agrobacterium tumefaciens VirB/D4 type IV secretion system (T4SS), a relative of the conju

245 nce of L. pneumophila depends on its Dot/Icm type IV secretion system (T4SS), which delivers more tha

246 A into the extracellular environment using a type IV secretion system (T4SS).

247 presses the elaboration of the H. pylori cag type IV secretion system (T4SS).

248 totic activity which depends on a functional type IV secretion system (T4SS).

249 es that are dependent on activity of the cag type IV secretion system (T4SS).

250 s via its cag pathogenicity island (cag PAI) type IV secretion system (T4SS).

251 The bacterium Brucella abortus uses a type IV secretion system (VirB T4SS) to generate a repli

252 ove-described findings were dependent on the type IV secretion system (VirB) and the secreted BPE005

253 ctor protein that is secreted by the Dot/Icm type IV secretion system and interferes with the caspase

254 wStr expresses 15 Vir proteins of a Type IV secretion system and its transcriptional regulat

255 Aggregation Substance, PrgC) and the Prg/Pcf type IV secretion system and, in turn, conjugatively tra

256 apid and required bacteria with a functional type IV secretion system called Dot/Icm.

257 BMEI 1330, a DegP/HtrA protease; BMEII 0029, type IV secretion system component VirB5; and BMEII 0691

258 We investigated the bacterial type IV secretion system core complex (T4SScc) by cellul

259 are delivered into host cells by the Dot/Icm type IV secretion system during infection.

260 us, which induces ER stress by injecting the type IV secretion system effector protein VceC into host

261 e use electron microscopy to reconstruct the type IV secretion system encoded by the Escherichia coli

262 on apparatus, the molecular mechanism of the type IV secretion system has proved difficult to dissect

263 Helicobacter pylori type IV secretion system injects the oncoprotein CagA in

264 The Agrobacterium tumefaciens VirB/VirD4 type IV secretion system is composed of a translocation

265 tiplication/defect in organelle trafficking) type IV secretion system targets the bacterial-derived M

266 rgB (aggregation substance) and PrgC - and a type IV secretion system through which the plasmid is de

267 vironment for replication and uses a Dot/Icm type IV secretion system to generate the large PV.

268 ncluding Legionella pneumophila, rely on the type IV secretion system to translocate a repertoire of

269 ila replicates within macrophages by using a type IV secretion system to translocate bacterial effect

270 ive agent of Legionnaire's disease, uses its type IV secretion system to translocate over 300 effecto

271 ject into gastric epithelial cells through a type IV secretion system where it can cause gastric aden

272 on of the conserved conjugation machinery (a type IV secretion system), and the potential to transfer

273 uisition of virulence factors that include a type IV secretion system, a perosamine-based O antigen,

274 ag proteins required for activity of the cag type IV secretion system, putative lipoproteins, and oth

275 a neotomaein vitro model system for study of type IV secretion system-dependent (T4SS) pathogenesis i

276 ellular destruction by restricting fusion of type IV secretion system-dependent Brucella-containing v

277 into the invaded host cell by the bacterial type IV secretion system.

278 ilm formation, nutrient acquisition, and the type IV secretion system.

279 recruited for transport by a plasmid-encoded type IV secretion system.

280 nslocated into the host cell via the Dot/Icm type IV secretion system.

281 into the host cell by the pathogen's Dot/Icm type IV secretion system.

282 Type IV secretion systems (T4SSs) are large multisubunit

283 Gram-negative bacteria use type IV secretion systems (T4SSs) for a variety of macro

284 rom one bacterium to another, is mediated by type IV secretion systems (T4SSs).

285 cretion apparatus in Brucella belongs to the type IV secretion systems present in many pathogenic bac

286 Bacterial type IV secretion systems translocate virulence factors

287 VI secretion, and, unexpectedly, conjugative type IV secretion within competing bacteria, induce P. a

288 Given the central role of VirD4 in type IV secretion, our study provides mechanistic insigh

289 ore complex (TraC and TraG) with homology to type IV secretion-like systems.

290 ducts (HR 3.711, P=0.008), Bismuth-Corlette type IV stricture (HR 2.082, P=0.008), obstruction due t

291 tal bile duct obstruction, Bismuth- Corlette type IV stricture, biliary obstruction caused by gallbla

292 ATPase 2 (ALA2) and the related ALA1 in the type IV subfamily of P-type ATPases as key components of

293 _2071 encodes an ATPase homologue of type II/type IV systems.

294 e (necrotizing) form of hypophysitis through type IV (T-cell dependent) and type II (IgG dependent) i

295 Legionella pneumophila utilizes the Dot/Icm type IV translocation system to proliferate within a vac

296 A secondary analysis of Fitzpatrick skin types IV, VI, and VI demonstrated a sustained interrater

297 sement membrane (BM) is composed of collagen types IV, VI, VII, and XVII, fibronectin, and laminin an

298 3, 1.08), or Fitzpatrick skin phototype (for type IV vs. type I, multivariable-adjusted RR = 0.99, 95

299 Microbiome type IV was not detected in healthy controls.

300 linical diagnosis of osteogenesis imperfecta type IV, we identified two homozygous variants in SPARC