ライフサイエンスコーパス: type VI collagen

1 bronectin, fibrillin-1, MAGP-1, decorin, and type VI collagen.

2 , and MAGP-1 and moderately with decorin and type VI collagen.

3 ell matrix and when it was bound to purified type VI collagen.

4 nctional interaction of these receptors with type VI collagen.

5 ha 1 beta 1 mediates chondrocyte adhesion to type VI collagen.

6 75% of the adhesion of human chondrocytes to type VI collagen.

7 subunit to block adhesion of chondrocytes to type VI collagen.

8 reated cells also have decreased adhesion to type VI collagen.

9 ted that the NG2 proteoglycan interacts with type VI collagen.

10 NG2 was shown to bind to pepsin-solubilized type VI collagen.

11 work we analysed the amino acid sequence of type VI collagen, a non-fibrillar collagen that forms an

12 Type VI collagen, a soluble extracellular matrix protein

13 These data indicate that two receptors for type VI collagen, alpha 3 beta 1 and NG2, are present du

14 The occasional co-localization of type VI collagen and fibrillin adjacent to internal elas

15 ayed dipeptidase activity and degraded human type VI collagen and fibrinogen, but not salivary amylas

16 re investigated the relationships among vWF, type VI collagen, and fibrillin in human vascular subend

17 and alpha2 chains, (2) type V collagen, (3) type VI collagen, and most recently (4) the laminin alph

18 llagen and interacts with type III collagen, type VI collagen, and type X collagen, but not with type

19 ple-helical domain or the globular domain of type VI collagen appear to cause Bethlem myopathy.

20 To identify type VI collagen binding proteins, the amino-terminal do

21 ave proposed that vWF is not associated with type VI collagen but rather with the thicker elastin-ass

22 ults are consistent with the hypothesis that type VI collagen, but not fibrillin-containing microfibr

23 lies and the alpha 1 and alpha 2 subunits of type VI collagen (COL6A1 and COL6A2) have been postulate

24 ith stable knockdown of COL6A1 revealed that type VI collagen-deficient matrices were significantly t

25 en and sulfated proteoglycans present in the type VI collagen-depleted matrices.

26 e corneal stroma is associated with abundant type VI collagen deposition.

27 sts cultured on de-cellularized CDMs lacking type VI collagen displayed increased cell spreading, mig

28 Type VI collagen filaments are found associated with int

29 The strong interaction of type VI collagen filaments with basement membrane collag

30 y of type VI collagen tetramers or stabilize type VI collagen filaments, a two-hybrid screen of a hum

31 n chromosome 2q where the alpha 3 subunit of type VI collagen has been localized.

32 study we examined the expression pattern of type VI collagen in normal and wounded skin and investig

33 onstrate for the first time that deletion of type VI collagen in this knockout model plays a critical

34 Colocalization of NG2 and type VI collagen indicated that this collagen was presen

35 ologically identical to decorin proteins and type VI collagen, indicating that the expression of spec

36 Taken together, these findings indicate that type VI collagen is a key regulator of dermal matrix ass

37 Type VI collagen is a nonfibrillar collagen expressed in

38 are closely associated with, and enmesh, the type VI collagen microfibrils and have structural simila

39 We found that vWF co-localizes only with the type VI collagen microfibrils in subendothelium but not

40 We previously presented evidence that type VI collagen microfibrils serve as a binding site fo

41 The classical double-beaded appearance of type-VI collagen microfibrils was evident on mica coated

42 ive supramolecular assemblies: fibrillin and type-VI collagen microfibrils.

43 s coding the alpha 1 and alpha 2 subunits of type VI collagen on chromosome 21q, we carried out linka

44 In addition to the type VI collagen polypeptides, an extra 68-kDa protein b

45 ix components such as laminin, tenascin, and type VI collagen, produces cells with mosaic characteris

46 hanol or dithiothreitol, the alpha chains of type VI collagen ran into the gel.

47 To clarify the role of this collagen, two type VI collagen receptors were studied during corneal d

48 We hypothesized that type VI collagen regulates matrix assembly and cell func

49 o effect on secretion of the alpha3 chain of type VI collagen, secretion of the protein hormone adipo

50 family linked to 2q37, implicating the three type VI collagen subunit genes, COL6A1 (chromosome 21),

51 eased release and evidence of proteolysis of type VI collagen subunits, cartilage oligomeric matrix p

52 ression of alpha 1 beta 1 and on adhesion to type VI collagen suggest that alpha 1 beta 1 mediates ch

53 o identify proteins that promote assembly of type VI collagen tetramers or stabilize type VI collagen

54 c muscle, a goat antibody recognizing bovine type VI collagen to stain the lining of vessels, and the

55 th tissue-derived decorin including collagen type VI, collagen type I, and fibronectin.

56 WF in the vascular subendothelium, where the type VI collagen-vWF complex may play an important role

57 Type VI collagen was adventitial or adventitial/medial.

58 Type VI collagen was expressed throughout the dermis of

59 Type VI collagen was extracted from cornea with urea and

60 Binding of NG2 to type VI collagen was shown to be concentration-dependent

61 bronectin, fibrillin-1, MAGP-1, decorin, and type VI collagen were all localized to clusters of the b

62 esenchyme cells and corneal fibroblasts with type VI collagen, whereas only a subset of cells express

63 decrease in the adhesion of chondrocytes to type VI collagen, while adhesion to type II collagen and