ライフサイエンスコーパス: typhi

1 specific antibodies of Salmonella typhi (S. typhi).

2 gellin (r-fla) protein of S. typhi (r-fla S. typhi).

3 nd compared to other available genomes of S. Typhi.

4 etect 1 colony-forming unit/mL of Salmonella Typhi.

5 ted outbreak, the first of ESBL-producing S. Typhi.

6 ainst the intracellular bacterium Salmonella Typhi.

7 gent, ezetimibe, reduced susceptibility to S Typhi.

8 obial killing more efficiently than other S. Typhi.

9 ngle cluster in OmpB from mildly virulent R. typhi.

10 e evolution and molecular epidemiology of S. Typhi.

11 by the bacterium Salmonella enterica serovar Typhi.

12 s type 1, Epstein Barr virus, and Salmonella typhi.

13 a rapid, simple and low-cost analysis of S. typhi.

14 y infection with Salmonella enterica serovar Typhi.

15 fied it as a secreted effector protein of R. typhi.

16 ecific pathogen, Salmonella enterica serovar Typhi.

17 reased NAL resistance of S. enterica serovar Typhi.

18 tlr11(-/-) mice can be immunized against S. Typhi.

19 ciently infected with orally administered S. Typhi.

20 tion effector protein that is absent from S. Typhi.

21 ng an established human infection model of S Typhi.

22 by which antibodies facilitate killing of S. Typhi.

23 ella enterica isolates that are not serotype Typhi.

24 nd how they impact on the pathogenesis of S. Typhi.

25 predominance of Salmonella enterica serovar Typhi.

26 sites were identified in S. enterica serovar Typhi, 22 of which were associated with OmpR-regulated g

27 human-adapted bacterial pathogen Salmonella Typhi (6,7) , the cause of typhoid fever in humans (8-12

28 ic acid (NAL-R) increased from 2008 to 2012 (Typhi, 60% to 68%; Paratyphi A, 91% to 94%).

29 in humans, can be lethally infected with S. Typhi, a breakthrough that promises to speed the develop

30 Unlike S. Typhimurium, S. Typhi, a human obligatory pathogen that causes typhoid f

31 cted colourimetrically using HRP labelled S. typhi Ab.

32 n and adults, respectively, while Salmonella Typhi accounted for 0.5% and 2.1%, respectively.

33 decarboxylase system allowed us to render S. Typhi acid resistant (to pH 2.5) on demand, with surviva

34 allenge with a small inoculum of virulent S. Typhi administered in bicarbonate solution can be perfor

35 enterocytes, and it has been assumed that S Typhi also preferentially targets M cells.

36 rculosis MgtC is highly homologous to its S. Typhi analogue, there does not appear to be an Mtb homol

37 were available for analysis (164 Salmonella Typhi and 784 iNTS).

38 those for animals infected with wild-type R. typhi and develop comparable pathology and bacterial loa

39 ficant transmission mechanism for Salmonella typhi and dysentery-causing pathogens in this urban popu

40 l for the study of the immune response to S. Typhi and for the development of vaccines against this i

41 Salmonella Typhi and iNTS were cultured from 194 (1.4%) and 840 (5.

42 the microbiological landscape of Salmonella Typhi and invasive nontyphoidal Salmonella (iNTS) in the

43 The epidemiology of Salmonella Typhi and invasive nontyphoidal Salmonella (NTS) differs

44 es revealed the interaction between r-fla S. typhi and Moab of r-fla S. typhi as spontaneous, endothe

45 ltaS were determined first time for r-fla S. typhi and Moab of r-fla S. typhi interactions and the va

46 Salmonella Typhi and NTS are major causes of BSI in DRC; their anti

47 crobial susceptibility results of Salmonella Typhi and Paratyphi A isolates sent for testing by parti

48 n Salmonella, two human-restricted serovars, Typhi and Paratyphi A, shared the highest number of gene

49 fever caused by Salmonella enterica serovars Typhi and Paratyphi is substantial and has high impact i

50 uman-restricted Salmonella enterica serovars Typhi and Paratyphi predominantly affects the most impov

51 0776, and (ii) native OmpBs purified from R. typhi and R. prowazekii strains Breinl, RP22, and Madrid

52 erica serovar Typhimurium, the genomes of S. Typhi and S. Paratyphi A are characterized by inactivati

53 GCxGC/TOFMS) on plasma from patients with S. Typhi and S. Paratyphi A infections and asymptomatic con

54 Our findings also suggest that S. Typhi and S. Typhimurium elicit different proinflammator

55 ages (MDMs) with Salmonella enterica serovar Typhi and S. Typhimurium will induce human cathelicidin

56 exhibit OmpR-dependent expression in both S. Typhi and S. Typhimurium.

57 t, together with Salmonella enterica serovar Typhi and Salmonella enterica serovar Sendai, causes ent

58 -pathogen interactions induced by Salmonella Typhi and Salmonella Paratyphi A during enteric fever ar

59 reaction (qPCR) method to detect Salmonella Typhi and Salmonella Paratyphi A simultaneously in blood

60 e set was able to detect clinical Salmonella Typhi and Salmonella Paratyphi A strains and also diarrh

61 Enteric fever, caused by Salmonella Typhi and Salmonella Paratyphi A, is the leading cause o

62 perimentally observed differences between S. typhi and Staphylococcus aureus enzymes.

63 Salmonella Typhi and Typhimurium diverged only approximately 50 000

64 Two major serovars of Salmonella enterica, Typhi and Typhimurium, have evolved a two-component regu

65 Serovars of Salmonella enterica, namely Typhi and Typhimurium, reportedly, are the bacterial pat

66 adults ingested escalating dose levels of S. Typhi and were closely monitored in an outpatient settin

67 4, 135 Salmonella enterica serotype Typhi (S Typhi) and 94 iNTS isolates were cultured from the blood

68 cific Salmonella enterica serovars Typhi (S. Typhi) and Paratyphi (S. Paratyphi) identified Rab29.

69 amushi), murine typhus (caused by Rickettsia typhi), and leptospirosis are common causes of febrile i

70 hogens (Streptococcus pneumoniae, Salmonella typhi, and Mycobacterium tuberculosis), we demonstrate t

71 IMD pathway could minimize the spread of R. typhi, and potentially other human pathogens, vectored b

72 Typhi, and survived lethal intranasal S. sonnei challeng

73 ic depolymerase enzyme missing in S enterica Typhi, and we exploited this enzyme to isolate acylated

74 inding site in the inter-operon region in S. Typhi, and were characterized using in vitro and in vivo

75 lla enterica and Salmonella enterica serovar Typhi, and Yersinia pestis), and 3 protozoa (Leishmania

76 containing 2,724 Salmonella enterica serovar Typhi antigens (>63% of proteome) and identified antibod

77 ugh SPI-7 within Salmonella enterica serovar Typhi appears to be fixed within the chromosome, we pres

78 between r-fla S. typhi and Moab of r-fla S. typhi as spontaneous, endothermic and entropy driven one

79 h the outbreak strain of Salmonella serotype Typhi, as determined by pulsed-field gel electrophoresis

80 degrees C or higher for 12 h or longer or S Typhi bacteraemia, following oral challenge administered

81 enome sequence, little is known regarding R. typhi biology in flea vectors that, importantly, do not

82 kettsia prowazekii and PKMT2 from Rickettsia typhi, both the apo form and in complex with its cofacto

83 n <5 years accounted for 20.3% of Salmonella Typhi BSI episodes.

84 he IMD pathway as a critical regulator of R. typhi burden in C. felis These data suggest that targeti

85 the intracellular human pathogen Salmonella Typhi, but its potential broader role in antimicrobial d

86 erium leprae and Salmonella enterica serovar Typhi, but the function of parkin in immunity has remain

87 Typhi by human macrophages up to 2.3-fold relative to pr

88 imiting disease, Salmonella enterica serovar Typhi can infect only humans causing typhoid fever, a li

89 apsular polysaccharide Vi Ag from Salmonella typhi can protect against typhoid fever, although the me

90 f typhoid fever, Salmonella enterica serovar Typhi, can partially subvert this critical innate immune

91 ruginosa, Klebsiella pneumoniae, Salmonellae typhi, Candida albicans, Rhizopus stolonifer, Aspergillu

92 producible metabolite profiles separating S. Typhi cases, S. Paratyphi A cases, and controls, calcula

93 Shigella sonnei and Salmonella Typhi cause significant morbidity and mortality.

94 rsinia pestis) and murine typhus (Rickettsia typhi) caused significant numbers of human cases in the

95 Salmonella enterica serovar Typhi causes an estimated 22 million cases of typhoid fe

96 Salmonella enterica serovar Typhi causes the systemic disease typhoid fever.

97 almonella enterica serovar Typhi (Salmonella Typhi) causes an estimated 22 million typhoid fever case

98 he crystal structure of DHQ1 from Salmonella typhi chemically modified by this ammonium derivative re

99 id not belong to the dominant H58 Salmonella Typhi clade.

100 icidal capacity and efficiently augmented S. Typhi clearance.

101 work we evolved Cytolysin A from Salmonella typhi (ClyA) to a high level of soluble expression and d

102 t of iNTS vaccines and the introduction of S Typhi conjugate vaccines should be considered for high-i

103 Typhi-containing vacuole but not to vacuoles containing

104 Native OmpB from virulent R. typhi contains mono- and trimethyllysines at locations w

105 ls of DeltaphoPQ, DeltapmrAB, and PhoP(c) S. Typhi decreased over time but were not further inhibited

106 ealed differences in the ability of these S. Typhi derivatives to invade cells or induce cellular res

107 approach provides an alternative way for S. typhi detection in less than 10 min.

108 Salmonella enterica serovar Typhi (S. Typhi) differs from most other salmonellae in that it ca

109 ion, with GTP-bound Arf6 localized to the R. typhi entry foci.

110 nding to the requirement of PI(4,5)P2 for R. typhi entry.

111 ilure was associated with the emergence of S Typhi exhibiting resistance against fluoroquinolones, re

112 cellular bacterial human pathogen Salmonella Typhi exhibits strict host specificity.

113 creased the odds of seroconversion of IgG S. Typhi flagella antibody (adjusted OR 6.4, 95% CI, 1.3-31

114 Hypothesizing that S. Typhi flagella plays a key role during infection, we con

115 fferences in the phenotypic properties of S. Typhi flagella variation and how they impact on the path

116 role during infection, we constructed an S. Typhi fliC mutant and otherwise isogenic S. Typhi strain

117 firmed case required isolation of Salmonella Typhi from blood or stool.

118 Antibody immobilized membranes captured S. typhi from buffer solution and this complex was detected

119 S. Typhi from Indonesia are a notable exception, with circu

120 ce polysaccharide Vi, which distinguishes S. Typhi from localized gastroenteritis-producing nontyphoi

121 two gtr operons that we identified in the S Typhi genome.

122 Thus, R. typhi(GFPuv) bacteria are a novel, potent tool to study

123 CB17 SCID mice infected with R. typhi(GFPuv) succumb to the infection with kinetics simi

124 Transformed R. typhi (R. typhi(GFPuv)) bacteria are viable, replicate with kineti

125 ecific restimulation of spleen cells from R. typhi(GFPuv)-infected BALB/c mice elicits gamma interfer

126 imicrobial usage is reshaping the current S. Typhi global population and may be driving the emergence

127 he transcontinental spread of the Salmonella Typhi H58 haplotype, improved estimates of the burden of

128 e antibiotic resistance island in Salmonella Typhi Haplotype 58.

129 S. Typhi has a monophyletic population structure, indicatin

130 sistant Salmonella enterica serovar Typhi (S Typhi) has been the main cause of enteric fever, but now

131 FQ-resistance mutations in S. Typhi have become common, hindering treatment and contro

132 ear epidemics of Salmonella enterica serovar Typhi have been reported from countries across eastern a

133 1,832 Salmonella enterica serovar Typhi (S. Typhi) identifies a single dominant MDR lineage, H58, th

134 Typhi IgG LPS antibodies was significantly higher among

135 rotavirus in 9%, Campylobacter in 5%, and S. Typhi in <1%.

136 th kinetics similar to those of wild-type R. typhi in cell culture, and stably maintain the plasmid a

137 graphic strip test was employed to detect S. typhi in human serum effectively, with high accuracy.

138 eria Salmonella enterica serovar (Salmonella typhi) in 10 muL of sample volume.

139 the rapid detection of Salmonella typhi (S. typhi) in human serum.

140 a serovar Typhimurium, the murine model of S Typhi, in which various ECM genes were deleted or added,

141 exchange factor BLOC-3 are permissive to S. Typhi infection and exhibit increased susceptibility to

142 ion and causal mechanisms between Salmonella Typhi infection and GBC have not been established.

143 Knockdown of Relish and Imd increased R. typhi infection levels, implicating the IMD pathway as a

144 nt, with chronic Salmonella enterica serovar Typhi infection reported as a significant risk factor.

145 Secreted early during R. typhi infection, RalF localizes to the host plasma membr

146 gical association between GBC and Salmonella Typhi infection, we show that Salmonella enterica induce

147 le animal model in which to study Salmonella Typhi infection.

148 portantly, do not suffer lethality due to R. typhi infection.

149 I(3,4,5)P3 and PI(3)P, negatively affects R. typhi infection.

150 lity to Salmonella enterica serovar Typhi (S Typhi) infection.

151 in clearance of Salmonella enterica serovar Typhi infections is poorly defined.

152 t-restricted lifestyle typical of Salmonella Typhi infections.

153 to R. typhi Initially, we determined that R. typhi infects Drosophila cells and increases antimicrobi

154 phalides felis) innate immune response to R. typhi Initially, we determined that R. typhi infects Dro

155 time for r-fla S. typhi and Moab of r-fla S. typhi interactions and the values revealed the interacti

156 Vi released by S. Typhi interacts with the membrane prohibitin complex and

157 and help identify recent introductions of S. Typhi into new or previously endemic locations, providin

158 RARP-1 was secreted by R. typhi into the host cytoplasm during in vitro infection

159 transcript abundance at various phases of R. typhi intracellular growth.

160 In addition to Salmonella Typhi, invasive nontyphoidal Salmonella are increasingly

161 Salmonella enterica serovar Typhi is a human host-adapted pathogen and some S. Typhi

162 Salmonella enterica serotype Typhi is a human pathogen causing 12 to 30% mortality an

163 Salmonella enterica serovar Typhi is a human-restricted Gram-negative bacterial path

164 which can infect a broad range of hosts, S. Typhi is a strict human pathogen.

165 Salmonella Typhi is an exclusive human pathogen that causes typhoid

166 Salmonella enterica serovar Typhi is associated with a disseminated febrile illness

167 n the main cause of enteric fever, but now S Typhi is being displaced by infections with drug-resista

168 f the putative type 1 secretion system of R. typhi is involved in the secretion process of RARP-1.

169 strain, indicating that FQ resistance in S. Typhi is not typically associated with fitness costs.

170 eveloped immunoassay for the detection of S. typhi is simple, easy to handle, sensitive specific, rep

171 Rickettsia typhi is the causative agent of endemic typhus, a diseas

172 Salmonella Typhi is the cause of typhoid fever, a disease that has

173 Salmonella enterica serovar Typhi is the etiological agent of typhoid fever.

174 Salmonella Typhi is the leading cause of childhood bacteremia in ce

175 Salmonella enterica serovar Typhi (S Typhi) is responsible for an estimated 20 million infect

176 fever, caused by Salmonella enterica serovar Typhi, is an important public health problem in resource

177 ever case with a Salmonella enterica serovar Typhi isolate showing extended spectrum beta-lactamase (

178 e (multidrug resistant [MDR]) was limited to Typhi isolates, primarily acquired in southern Asia (13%

179 NTS isolates and 46.2% (12/26) of Salmonella Typhi isolates.

180 phoresis (PFGE) were performed on Salmonella Typhi isolates.

181 IgG against S. Typhi lipopolysaccharide (LPS) O and flagella was measur

182 These results suggest that S Typhi may preferentially target enterocytes in vivo.

183 Our findings reveal a mechanism by which S. Typhi may target T-cell immunity during establishment of

184 Typhi: mean postvaccination bactericidal antibody titers

185 Accordingly, we assessed R. typhi-mediated flea IMD pathway activation in vivo using

186 of NTS meningitis and 9 cases of Salmonella Typhi meningitis.

187 te the formation of a heterodimer between S. Typhi MgtR and the transmembrane helix 4 of Mtb MgtC.

188 SCV environment, as toxin produced by an S. Typhi mutant with impaired trafficking is not properly s

189 ereas 86% (131/152) were serovars other than Typhi (nontyphoidal Salmonella).

190 eate a test and control zone, antibody of S. typhi O901 and an anti-IgG were dotted on the nitrocellu

191 by the specific binding of antigens from S. typhi O901 and antibody of S. typhi O901 on a nitrocellu

192 tigens from S. typhi O901 and antibody of S. typhi O901 on a nitrocellulose membrane.

193 carrier state of Salmonella enterica serovar Typhi occurs in the bile-rich gallbladder and is frequen

194 between both pathogens is the presence in S. Typhi of TviA, a regulatory protein that shuts down flag

195 ombinantly expressed fragments of Rickettsia typhi OmpB exposed in vitro to trimethyltransferases of

196 al water borne pathogen Salmonella typhi (S. typhi) on modified isopore polycarbonate (PC) black memb

197 c infection with Salmonella enterica serovar Typhi or Paratyphi pathovars A, B or C(1).

198 MDMs infected with wild-type (WT) S. Typhi or S. Typhimurium released similar levels of proin

199 s not induced in human MDMs infected with S. Typhi or S. Typhimurium.

200 monella enterica subspecies enterica serovar Typhi or Salmonella enterica subspecies enterica serovar

201 gnosis of enteric fever caused by Salmonella Typhi or Salmonella Paratyphi A or B is bone marrow cult

202 es positive for Salmonella enterica serotype Typhi, or Paratyphi A, B, or C) on day 8; or relapse or

203 ective IgM responses can be elicited by a S. Typhi outer-membrane protein C- and F-based subunit vacc

204 C-42 degrees C) Salmonella enterica serovars Typhi, Paratyphi A, and Sendai significantly attenuate t

205 Many of the core genes affected by Typhi/Paratyphi A-specific mutations have known virulenc

206 Typhi/Paratyphi were isolated from blood.

207 Following oral ingestion of S Typhi, participants were assessed with daily blood cultu

208 The unique features of S. Typhi pathogenesis and its stringent host specificity ha

209 is a human host-adapted pathogen and some S. Typhi patients become asymptomatic carriers.

210 The adjusted incidence rate (AIR) of S Typhi per 100 000 person-years of observation ranged fro

211 ow designated genotype 4.3.1), the global S. Typhi population is highly structured and includes dozen

212 ted here can be used to interrogate local S. Typhi populations and help identify recent introductions

213 In conclusion, repeated vaccination with S. Typhi porins programs type I T follicular helper cell re

214 supporting the alternative hypothesis that S Typhi preferentially targets enterocytes.

215 w human challenge model and ascertain the S. Typhi (Quailes strain) inoculum required for an attack r

216 recombinant flagellin (r-fla) protein of S. typhi (r-fla S. typhi).

217 Transformed R. typhi (R. typhi(GFPuv)) bacteria are viable, replicate w

218 Among Salmonella Typhi, rates of multidrug resistance and decreased cipro

219 Enteric fever caused by Salmonella Typhi remains a major public health problem in developin

220 phoid toxin, a unique virulence factor of S. Typhi, reproduces many of the acute symptoms of typhoid

221 zae, S suis) and O tsutsugamushi, Rickettsia typhi/Rickettsia spp, and Leptospira spp infections in b

222 Our data suggest that R typhi/Rickettsia spp, O tsutsugamushi, and Leptospira sp

223 lity (236/876 [27%]), with 18% (13/71) for R typhi/Rickettsia spp, O tsutsugamushi, and Leptospira sp

224 infections were caused by O tsutsugamushi, R typhi/Rickettsia spp, or Leptospira spp.

225 of Rickettsia prowazekii RP027-028 and of R. typhi RT0101 and to monomethyltransferases of R. prowaze

226 ransferases of R. prowazekii RP789 and of R. typhi RT0776, and (ii) native OmpBs purified from R. typ

227 n 31, 2014, 135 Salmonella enterica serotype Typhi (S Typhi) and 94 iNTS isolates were cultured from

228 tidrug-resistant Salmonella enterica serovar Typhi (S Typhi) has been the main cause of enteric fever

229 usceptibility to Salmonella enterica serovar Typhi (S Typhi) infection.

230 Salmonella enterica serovar Typhi (S Typhi) is responsible for an estimated 20 milli

231 human-specific Salmonella enterica serovars Typhi (S. Typhi) and Paratyphi (S. Paratyphi) identified

232 Salmonella enterica serovar Typhi (S. Typhi) differs from most other salmonellae in

233 nalysis of 1,832 Salmonella enterica serovar Typhi (S. Typhi) identifies a single dominant MDR lineag

234 eloped for the rapid detection of Salmonella typhi (S. typhi) in human serum.

235 emely lethal water borne pathogen Salmonella typhi (S. typhi) on modified isopore polycarbonate (PC)

236 he population of Salmonella enterica serovar Typhi (S. Typhi), the causative agent of typhoid fever,

237 flagellin specific antibodies of Salmonella typhi (S. typhi).

238 ight into the molecular bases for Salmonella Typhi's host specificity and may help the development of

239 We designed primers for genes specific to S. Typhi, S. Paratyphi A, and genes conserved among Salmone

240 ablished that the human-adapted typhoidal S. Typhi, S. Paratyphi A, and S. Sendai are all noticeably

241 Blood samples spiked with in vitro grown S. Typhi, S. Paratyphi A, S. Typhimurium, and E. coli were

242 Salmonella enterica serovar Typhi (Salmonella Typhi) causes an estimated 22 million

243 effect against Escherichia coli, Salmonella typhi, Shigella dysenteriae, Streptococcus pneumoniae an

244 Typhi-specific antibodies following vaccination with a n

245 nvolving 21 067 Salmonella enterica serotype Typhi (ST) and S. enterica serotype Paratyphi A (SPA) is

246 An S. Typhi strain engineered to express GtgE and therefore ab

247 live attenuated Salmonella enterica serovar Typhi strain to create a bivalent mucosal plague vaccine

248 vaccination with live-attenuated Salmonella Typhi strain Ty21a is modestly efficacious, but the mech

249 monella enterica subspecies enterica serovar Typhi strain with resistance against beta-lactams, cepha

250 Typhi fliC mutant and otherwise isogenic S. Typhi strains expressing the Hj, Hd, Hz66 flagella antig

251 a tissue culture M cell model, we examined S Typhi strains with a deletion in the stg fimbriae.

252 e data safety and monitoring board because S Typhi strains with high-level resistance to ciprofloxaci

253 we assayed the fitness of eleven isogenic S. Typhi strains with resistance mutations in the FQ target

254 tness advantage relative to other Salmonella Typhi strains.

255 ions for the management of drug-resistant S. Typhi, suggesting that FQ-resistant strains would be nat

256 r major causes of FBD deaths were Salmonella Typhi, Taenia solium and hepatitis A virus.

257 xin, a unique virulence factor of Salmonella Typhi (the cause of typhoid fever), recapitulates in an

258 ion of Salmonella enterica serovar Typhi (S. Typhi), the causative agent of typhoid fever, exhibits l

259 sing bacteria, but experiments on Salmonella Typhi, the bacteria that causes Typhoid fever, are now c

260 Rickettsia typhi, the causative agent of murine (endemic) typhus, i

261 Salmonella enterica serovar Typhi, the causative agent of typhoid fever in humans, f

262 Salmonella Typhi, the causative agent of typhoid fever, is a monoph

263 an essential virulence factor of Salmonella Typhi, the cause of typhoid fever.

264 Salmonella enterica serovar Typhi, the cause of typhoid, is host restricted to human

265 For flea-borne Rickettsia typhi, the etiological agent of murine typhus, research

266 This mechanism allowed S. Typhi to dampen inflammasome activation, leading to redu

267 e regulation of virulence factors enables S. Typhi to evade innate immune recognition by concealing a

268 Paratyphi A and Salmonella enterica serovar Typhi to induce protective immunity against bacterial pa

269 st Salmonella Typhimurium allowed Salmonella Typhi to survive and replicate within macrophages and ti

270 of a BLOC complex was sufficient to allow S. Typhi to survive within mouse macrophages.

271 , Enterococcus, P. aeruginosa and Salmonella typhi) to antibiotics such as ampicillin and kanamycin.

272 Importantly, expression of R. typhi tolC in the E. coli tolC mutant restored the secre

273 Introduction of the S. Typhi tviA gene into S. Typhimurium suppressed antigen p

274 influenzae, and Salmonella enterica serovar Typhi/Typhimurium.

275 n factors (Arfs), is critical for Rickettsia typhi (typhus group rickettsiae) entry but pseudogenized

276 nd 40 without the haplotype (OO) underwent S Typhi vaccination.

277 iduals were randomized to receive Salmonella typhi vaccine (a model of acute inflammation) or placebo

278 Typhi vaccine (Ty21a) by using it as a vector to develop

279 tion of US adults with attenuated Salmonella Typhi vaccine CVD 908-htrA.

280 ance survival of Salmonella enterica serovar Typhi vaccine strains at pHs 3.0 and 2.5 to compensate f

281 hance humoral immunity to oral attenuated S. Typhi vaccine.

282 Typhoid toxin is a S. Typhi virulence factor that can reproduce most of the ty

283 Furthermore, S. Typhi was able to survive in macrophages from mice defec

284 ptomatic bacteremia and stool shedding of S. Typhi was also observed.

285 (ESBL)-producing Salmonella enterica serovar Typhi was identified, whole-genome sequence typed, among

286 Salmonella Typhi was isolated from 11 (0.3%) children at Teule and

287 aths from typhoid fever occurred; Salmonella Typhi was isolated from 27 (33%) of 81 patients.

288 Multidrug-resistant S Typhi was isolated in Ghana, Kenya, and Tanzania (both s

289 ical patients presenting to QECH; Salmonella Typhi was isolated on 2054 occasions (1.2%) and nontypho

290 Flagellin protein of S. typhi was prepared by recombinant DNA technology.

291 Typhi was reduced as much as 50% when opsonized with pos

292 ense, invasive NTS was common and Salmonella Typhi was uncommon, whereas the inverse was observed at

293 ts experimentally infected with wild-type S. Typhi, we detected significant cytokine responses within

294 type antibodies (Abs) against whole cell S. typhi were immobilized on them by following the amine gl

295 r spp, Neisseria gonorrhoeae, and Salmonella typhi were included in the high-priority tier.

296 Typhi when the bacteria were opsonized with postvaccinat

297 4% (21/152) were Salmonella enterica serovar Typhi, whereas 86% (131/152) were serovars other than Ty

298 t pathogenic Salmonella including Salmonella Typhi which causes systemic infection, typhoid, in human

299 yphimurium from 2002 to 2008, and Salmonella Typhi, which began in 2011 and was ongoing in 2014.

300 for the first time the transformation of R. typhi with the pRAM18dRGA plasmid that originally derive