ライフサイエンスコーパス: ubiquitin-dependent

1 ytic activity of 26 S proteasome is ATP- and ubiquitin-dependent.

2 degradation, both ubiquitin-independent and ubiquitin-dependent.

3 tilizing both autophagic-lysosomal (ALD) and ubiquitin-dependent 26S proteasomal (UPD) degradation pa

4 They are degraded by the ubiquitin-dependent 26S proteasome.

5 cytosolic RING domain, and proceeds via the ubiquitin-dependent 26S proteosome pathway.

6 dispensable for chromatin ubiquitylation and ubiquitin-dependent accumulation of repair factors at DS

7 Further studies indicate that ubiquitin-dependent activation of ataxin-3 at Lys-117 is

8 Thus, ubiquitin-dependent and -independent pathways robustly c

9 The potential cross-talk between the ubiquitin-dependent and -independent protein quality con

10 tes in vitro, it inhibits the degradation of ubiquitin-dependent and -independent substrates in vivo.

11 when expressed at the C-terminal regions of ubiquitin-dependent and -independent substrates of the 2

12 a family of trafficking adaptors, stimulate ubiquitin-dependent and clathrin-mediated endocytosis by

13 Degradation of XBP-1u involves both ubiquitin-dependent and ubiquitin-independent mechanisms

14 level of SRC-3 is tightly regulated by both ubiquitin-dependent and ubiquitin-independent proteasoma

15 s by coordinate enzymatic inhibition of both ubiquitin-dependent and ubiquitin-independent proteolyti

16 he capsid cores of retroviruses and activate ubiquitin-dependent antiviral responses upon capsid reco

17 UBs) suggests they remove ubiquitin to evade ubiquitin-dependent antiviral responses; however, this h

18 ependent ubiquitination of ELKS leads to the ubiquitin-dependent assembly of TAK1/TAB2/3 and NEMO/IKK

19 ition of Valosin-Containing Protein (VCP), a ubiquitin-dependent ATPase whose human homolog is linked

20 obacterium tuberculosis infection stimulates ubiquitin-dependent autophagy and inflammatory cytokine

21 BCR ubiquitination, trafficking to MIIC, and ubiquitin-dependent BCR-mediated antigen processing and

22 on but still able to down regulate B7.2 in a ubiquitin-dependent but endocytosis-independent manner.

23 ion can be broadly grouped into two classes, ubiquitin-dependent cargo recognition versus ubiquitin-i

24 lias p97 or VCP) is a key player in multiple ubiquitin-dependent cell signaling, degradation, and qua

25 creens for identification of antagonizers of ubiquitin-dependent cellular responses.

26 Cdc48/p97 is an evolutionary conserved ubiquitin-dependent chaperone involved in a broad array

27 ators is also required for execution of this ubiquitin-dependent chromatin response.

28 assembly regions, demonstrating that Gag has ubiquitin-dependent, cis-acting late domain activities l

29 revealed that infection supernatants elicit ubiquitin-dependent class II downregulation and degradat

30 gest that DnaJA1 triages all tau species for ubiquitin-dependent clearance mechanisms.

31 y which a specific E3 ligase is required for ubiquitin-dependent control of pAKT dynamics in a ligand

32 TOR-independent linkage between PTEN and the ubiquitin-dependent control of protein stability.

33 Ca(2+), which leads to CSF inactivation and ubiquitin-dependent cyclin destruction through the anaph

34 SL2, a novel E3 ligase for p53 that promotes ubiquitin-dependent cytoplasmic p53 localization.

35 atrix proteins might exit the peroxisome for ubiquitin-dependent cytosolic degradation.

36 a histone H2A DUB which negatively regulates ubiquitin-dependent DDR signaling.

37 ylation of a terminal phosphodegron promotes ubiquitin-dependent degradation (the phosphorylation of

38 erminal domain of PTEN, thereby resulting in ubiquitin-dependent degradation and diminished abundance

39 ated to the cytosol for proteasome-mediated, ubiquitin-dependent degradation by a process termed endo

40 S1 may allow the translocated toxin to avoid ubiquitin-dependent degradation by the 26S proteasome, w

41 of the 19S regulatory particle essential for ubiquitin-dependent degradation by the proteasome.

42 ed for genomic stability and is targeted for ubiquitin-dependent degradation in a cell cycle-dependen

43 data suggesting that alpha4 is regulated by ubiquitin-dependent degradation mediated by MID1.

44 coproteins, including c-Myc, is regulated by ubiquitin-dependent degradation mediated by the SCF(Fbw7

45 studies have shown that AKR1B10 mediates the ubiquitin-dependent degradation of acetyl-CoA carboxylas

46 ls, we determined that USP28 antagonizes the ubiquitin-dependent degradation of c-MYC, a known USP28

47 Ubiquitin-dependent degradation of Cdc25A is a major mec

48 KL001 prevented ubiquitin-dependent degradation of CRY, resulting in len

49 We also show that aspirin causes rapid, ubiquitin-dependent degradation of cyclin D1, a known p3

50 asitas B lymphoma protein (Cbl) controls the ubiquitin-dependent degradation of EGF receptor (EGFR),

51 mal degradation of unstructured proteins and ubiquitin-dependent degradation of folded proteins when

52 Ubiquitin-dependent degradation of hormone receptors is

53 ack regulation of insulin signaling involves ubiquitin-dependent degradation of insulin receptor subs

54 ty of surface pMHC-II in DCs is regulated by ubiquitin-dependent degradation of internalized pMHC-II.

55 (JA) activates gene expression by promoting ubiquitin-dependent degradation of jasmonate ZIM domain

56 he F-box protein COI1 triggers the SCF(COI1)/ubiquitin-dependent degradation of JASMONATE ZIM-DOMAIN

57 ell-cycle transitions are driven by waves of ubiquitin-dependent degradation of key cell-cycle regula

58 The suppression is achieved through the ubiquitin-dependent degradation of Mitofusin, which itse

59 TRAF2 and TRAF3 in this aspect is to mediate ubiquitin-dependent degradation of nuclear factor-kappaB

60 cell lines, ionizing radiation (IR) induces ubiquitin-dependent degradation of p21(Cip1).

61 ion of these lysine residues is required for ubiquitin-dependent degradation of p53.

62 re, we show that Upf complex facilitates the ubiquitin-dependent degradation of products derived from

63 We found that the ubiquitin-dependent degradation of Rpn4 can be mediated

64 Here we studied the mechanism underlying ubiquitin-dependent degradation of Rpn4, a transcription

65 identified the mub1Delta mutant defective in ubiquitin-dependent degradation of Rpn4.

66 nteracts with Ubr2, is also required for the ubiquitin-dependent degradation of Rpn4.

67 we investigated the mechanism underlying the ubiquitin-dependent degradation of Rpn4.

68 Here we show that both ubiquitin-dependent degradation of Stp1 and Stp2 and the

69 uggesting that Rfp/Slx8 proteins may promote ubiquitin-dependent degradation of SUMOylated targets.

70 in inhibiting the production of TGF-beta1 by ubiquitin-dependent degradation of Syk.

71 rate that CHIP is a primary component in the ubiquitin-dependent degradation of tau.

72 To promote ubiquitin-dependent degradation of the folded domains of

73 Ubiquitin-dependent degradation of the PRLr that negativ

74 and animal development, guided by selective ubiquitin-dependent degradation of the sperm-borne mitoc

75 k1-cyclin B1 and becomes unleashed only upon ubiquitin-dependent degradation of these regulators.

76 lin) is an E3 ubiquitin ligase that promotes ubiquitin-dependent degradation of Thr286-phosphorylated

77 feeding by promoting the phosphorylation and ubiquitin-dependent degradation of TORC2.

78 histidine-rich domain that was essential for ubiquitin-dependent degradation of ZIP4 and protection a

79 tine-insensitive 1 (COI1) to, and subsequent ubiquitin-dependent degradation of, jasmonate ZIM domain

80 alpha-synuclein aggregation by blocking its ubiquitin-dependent degradation pathways and promoting i

81 We provide evidence that two distinct ubiquitin-dependent degradation pathways for beta-cateni

82 e 26S proteasome recognizes a vast number of ubiquitin-dependent degradation signals linked to variou

83 reased hypothalamic SF-1 levels by promoting ubiquitin-dependent degradation, and sumoylation was req

84 ting cell cycle and cell growth proteins for ubiquitin-dependent degradation, but the diverse develop

85 The stability of p53 is tightly regulated by ubiquitin-dependent degradation, driven mainly by the ub

86 ased the ability of Keap1 to target Nrf2 for ubiquitin-dependent degradation, resulting in stabilizat

87 specific cell cycle regulatory proteins for ubiquitin-dependent degradation, thereby controlling cel

88 OR1-bound, transcriptionally-inactive AR for ubiquitin-dependent degradation, thereby promoting expre

89 lso targets additional signaling factors for ubiquitin-dependent degradation, thereby regulating impo

90 argeting NF-kappaB-inducing kinase (NIK) for ubiquitin-dependent degradation, thus preventing process

91 pSPKLpS(1365) of topoIIalpha, leading to its ubiquitin-dependent degradation.

92 t from Annexin 2 and making it accessible to ubiquitin-dependent degradation.

93 oa10 recognition, protecting Hcn1/Cdc26 from ubiquitin-dependent degradation.

94 d promotes its stabilization by antagonizing ubiquitin-dependent degradation.

95 ts nuclear localization in beta cells or its ubiquitin-dependent degradation.

96 anges may reveal or mask the signals for the ubiquitin-dependent degradation.

97 SUMOylation can serve as a direct signal for ubiquitin-dependent degradation.

98 obstructed kidney is mediated by an enhanced ubiquitin-dependent degradation.

99 nfolding, which may provide a signal for the ubiquitin-dependent degradation.

100 p53 protein in a cell is normally limited by ubiquitin-dependent degradation.

101 ngly stabilizes PGC-1alpha by inhibiting its ubiquitin-dependent degradation.

102 phenotype and targets Rb for proteasome- and ubiquitin-dependent degradation.

103 ast in response to cellular requirements for ubiquitin-dependent degradation.

104 d at the metaphase-to-anaphase transition by ubiquitin-dependent degradation.

105 Whereas ubiquitin-dependent degrons have been characterized in s

106 ), a sophisticated process that mediates the ubiquitin-dependent delivery of substrates to the 26S pr

107 Accumulation of this factor is limited by ubiquitin-dependent destabilization, apparently mediated

108 ticulum (ER) are dislocated and targeted for ubiquitin-dependent destruction by the proteasome.

109 g proteins such as securin and cyclin B1 for ubiquitin-dependent destruction by the proteasome.

110 The Golgi apparatus undergoes a ubiquitin-dependent disassembly and reassembly process d

111 e on PCNA, an antagonistic action of SUMO on ubiquitin-dependent DNA damage tolerance has been propos

112 been shown to be involved in regulating the ubiquitin-dependent down-regulation of activated cell su

113 in EOMG implies disease mechanisms involving ubiquitin-dependent dysregulation of NF-kappaB signaling

114 otch signaling pathway, participating in the ubiquitin-dependent endocytosis of Delta.

115 The HRD pathway is a conserved route of ubiquitin-dependent, endoplasmic reticulum (ER)-associat

116 for Galphas as an integral component of the ubiquitin-dependent endosomal sorting machinery and high

117 rs, not viral proteins, appears critical for ubiquitin-dependent enveloped viral particle release.

118 of late endosomes (multivesicular bodies), a ubiquitin-dependent event that requires the coordinated

119 ng it for degradation by the proteasome in a ubiquitin-dependent fashion, independently of MDM2 or Pi

120 This ubiquitin-dependent folding system also controls the pro

121 t highlight the diversity and specificity of ubiquitin dependent functions in immune cells.

122 facilitates Crn7 targeting to TGN through a ubiquitin-dependent interaction with Eps15.

123 Interestingly, CYLD targets a ubiquitin-dependent kinase, transforming growth factor-b

124 By investigating ubiquitin-dependent lysosomal degradation of the interfe

125 HNE-modified proteins are also degraded in a ubiquitin-dependent lysosomal pathway, lens epithelial c

126 a dual mechanism that concurrently promotes ubiquitin-dependent lysosomal sorting of the receptor an

127 1 destruction and is degraded in a Plk1- and ubiquitin-dependent manner in early mitosis.

128 duces relocalization of the IKK complex in a ubiquitin-dependent manner, and dynamic changes in the s

129 zing to different cellular compartments in a ubiquitin-dependent manner.

130 K293 cells, was transported to exosomes in a ubiquitin-dependent manner.

131 In this study, we identified an ubiquitin-dependent mechanism by which BRCA1 inhibits tr

132 h BAF155, suggesting that in addition to the ubiquitin-dependent mechanism of BAF57 degradation, ther

133 is targeted for lysosomal degradation via a ubiquitin-dependent mechanism that involves the endosoma

134 ubiquitin-regulated and that Rip2 employs a ubiquitin-dependent mechanism to achieve NF-kappaB activ

135 se studies suggest that Rip1 uses a similar, ubiquitin-dependent mechanism to activate IkappaB kinase

136 within MVBs occurs via a well-characterized ubiquitin-dependent mechanism, which is blocked by acute

137 t alphakap promoted AChRalpha stability by a ubiquitin-dependent mechanism.

138 ulates the NF-kappaB signaling pathway by an ubiquitin-dependent mechanism.

139 These results indicate that distinct ubiquitin-dependent mechanisms are employed for IKK acti

140 Ubiquitin-dependent mechanisms have emerged as essential

141 this system is impaired by mutation of Vms1, ubiquitin-dependent mitochondrial protein degradation, m

142 e report here that LLO is a substrate of the ubiquitin-dependent N-end rule pathway, which recognizes

143 that can act as a degradation signal for the ubiquitin-dependent N-end rule pathway.

144 Ubiquitin-dependent NCOA4 turnover is promoted by excess

145 aining vesicles is transient and followed by ubiquitin-dependent NDP52 recruitment.

146 urther show that CYLD negatively regulates a ubiquitin-dependent NF-kappaB activator, RIP1.

147 esults suggest TIEG and Itch contribute to a ubiquitin-dependent nonproteolytic pathway that regulate

148 sphorylates serine-85 of NEMO to promote its ubiquitin-dependent nuclear export.

149 dily remove both recognition subunits by the ubiquitin-dependent p97/VCP/Cdc48 segregase complex, lea

150 BCR complexes to MVB-like MIIC occurs via an ubiquitin-dependent pathway and that ubiquitination of A

151 Inhibition of the ubiquitin-dependent pathway by the chemical proteasome i

152 Here, we define an atypical ubiquitin-dependent pathway for p38 activation used by P

153 , our work reveals a previously unrecognized ubiquitin-dependent pathway induced specifically to repa

154 4/NOT in the regulation of H3K4me3 through a ubiquitin-dependent pathway that likely involves the pro

155 which limits channel availability through a ubiquitin-dependent pathway.

156 g of Tau degradation toward a less efficient ubiquitin-dependent pathway.

157 ia the proteasome link this polyQ protein to ubiquitin-dependent pathways already implicated in disea

158 e for distinct, post-translationally active, ubiquitin-dependent pathways capable of controlling the

159 Here, we determined that ubiquitin-dependent pathways regulate neuromuscular path

160 entable pathway related, and in genes in the ubiquitin-dependent pathways such as USP9X.

161 At least two different ubiquitin-dependent pathways target alpha2 for destructi

162 enzymes (DUbs) play important roles in many ubiquitin-dependent pathways, yet how DUbs themselves ar

163 lly activate both degradative and regulatory ubiquitin-dependent pathways.

164 C-terminus alpha6 helix through two parallel ubiquitin-dependent pathways: the ESCRT-I-ESCRT-II-Vps20

165 thus promoting the degradation of Bub1 in a ubiquitin-dependent process.

166 s involved in many cellular events including ubiquitin-dependent processes and membrane fusion.

167 Ubiquitin-dependent processes are critical for propagati

168 Since ubiquitin-dependent processes are usually mediated by ce

169 ions is challenging the current dogma on how ubiquitin-dependent processes culminate in the activatio

170 ing enzyme catalyzes the initial step in all ubiquitin-dependent processes.

171 al machinery that are directly controlled by ubiquitin-dependent processes.

172 achieve regulatory roles in many aspects of ubiquitin-dependent processes.

173 ubiquitination and play an important role in ubiquitin-dependent processes.

174 it is not clear how the 26S proteasome, the ubiquitin-dependent protease that is only capable of deg

175 the three synuclein proteins inhibited 26 S ubiquitin-dependent proteasomal activity.

176 degradation has indicated that CYPs 3A incur ubiquitin-dependent proteasomal degradation (UPD) in an

177 that incurs endoplasmic reticulum-associated ubiquitin-dependent proteasomal degradation (UPD).

178 hnRNP K ensues through the inhibition of its ubiquitin-dependent proteasomal degradation mediated by

179 RIB2 and C/EBPalpha p42 for the K48-specific ubiquitin-dependent proteasomal degradation of C/EBPalph

180 proteins implicated in the regulation of the ubiquitin-dependent proteasomal degradation of cellular

181 ition of Hsp90 with geldanamycin resulted in ubiquitin-dependent proteasomal degradation of KDM4B, bu

182 hysical complex with SnoN and stimulates the ubiquitin-dependent proteasomal degradation of SnoN in n

183 ptional repression of AR by facilitating the ubiquitin-dependent proteasomal degradation of the trans

184 rom the endoplasmic reticulum (ER) through a ubiquitin-dependent proteasomal degradation pathway.

185 air proteins to the CRL4-DCAF1 E3 ligase for ubiquitin-dependent proteasomal degradation.

186 hed that Myc levels are in part regulated by ubiquitin-dependent proteasomal degradation.

187 ligase ITCH, which bound and target WBP2 for ubiquitin-dependent proteasomal degradation.

188 at orthologs are phosphorylated during their ubiquitin-dependent proteasomal degradation.

189 r stabilizing beta-catenin by inhibiting its ubiquitin-dependent proteasomal degradation.

190 of cIAP1, an E3 ligase that targets CAS for ubiquitin-dependent proteasomal degradation.

191 ate that the level of Dnmt1 is controlled by ubiquitin-dependent proteasomal degradation.

192 of BRCA1 expression is determined in part by ubiquitin-dependent proteasomal degradation.

193 n from p53, which induces HDAC3 cleavage and ubiquitin-dependent proteasomal degradation.

194 ndance of PTEN was reversed by inhibition of ubiquitin-dependent proteasomal degradation.

195 eps: substrate recognition, dislocation, and ubiquitin-dependent proteasomal destruction.

196 ients, causing their degradation through the ubiquitin-dependent proteasomal pathway.

197 retards the degradation of hTDO through the ubiquitin-dependent proteasomal pathway.

198 Both classes of genes encode ubiquitin-dependent proteasome adapters, which recruit d

199 s compared with wild-type, and inhibition of ubiquitin-dependent proteasome degradation prevented TPA

200 tion with Bcl-6 and protection of Bcl-6 from ubiquitin-dependent proteasome degradation.

201 tumors, induces Ski degradation through the ubiquitin-dependent proteasome in malignant human cancer

202 ever, loss of myosin was associated with the ubiquitin-dependent proteasome pathway, which suggests t

203 lity of E2 that is normally degraded via the ubiquitin-dependent proteasome pathway.

204 sfolded proteins for degradation through the ubiquitin-dependent proteasome pathway.

205 G132, indicating that it is degraded via the ubiquitin-dependent proteasome pathway.

206 in that regulates the degradation of several ubiquitin-dependent proteasome substrates.

207 ndoplasmic reticulum (ER) are cleared by the ubiquitin-dependent proteasome system in the cytosol, a

208 g E3 ubiquitin ligases target substrates for ubiquitin-dependent, proteasome-mediated degradation and

209 important, evolutionarily conserved roles in ubiquitin dependent protein degradation.

210 redundancy among cellular DUBs that restrict ubiquitin-dependent protein assembly at DSBs.

211 In addition, a set of host genes involved in ubiquitin-dependent protein catabolism affected both TBS

212 Forty genes in ubiquitin-dependent protein catabolism, protein biosynth

213 on domain-binding protein 1 (JAB1) regulates ubiquitin-dependent protein degradation by deneddylation

214 ubiquitin system in early development, where ubiquitin-dependent protein degradation governs such div

215 TP-dependent protease complexes that execute ubiquitin-dependent protein degradation in eukaryotes, c

216 Ubiquitin-dependent protein degradation is essential for

217 Although ubiquitin-dependent protein degradation is impaired in c

218 Ubiquitin-dependent protein degradation is used as a reg

219 ase in protein synthesis, but a reduction in ubiquitin-dependent protein degradation pathways was als

220 reported that modification at Lys-6 inhibits ubiquitin-dependent protein degradation, a failure of th

221 Ubiquitin-dependent protein degradation, hydrolysis of s

222 atory particle that normally participates in ubiquitin-dependent protein degradation, is required for

223 iquitin ligase complex, which is involved in ubiquitin-dependent protein degradation.

224 phorylation events and distinct mediators of ubiquitin-dependent protein degradation.

225 studies, the role of PPARbeta in modulating ubiquitin-dependent protein kinase Calpha (PKCalpha) lev

226 his review is the finding of a mitochondrial ubiquitin-dependent protein quality control and that thi

227 presents an important point of regulation in ubiquitin-dependent protein quality control.

228 ns, which suggest that ataxin-3 functions in ubiquitin-dependent protein surveillance.

229 ons or structurally related determinants for ubiquitin-dependent proteolysis and perhaps other proces

230 the data suggest that Int6 depletion blocks ubiquitin-dependent proteolysis by decreasing both ubiqu

231 Ubiquitin-dependent proteolysis can initiate at ribosome

232 ns with expanded polyglutamine tracts impair ubiquitin-dependent proteolysis due to their propensity

233 s also demonstrate that KLF4 is targeted for ubiquitin-dependent proteolysis during cell cycle progre

234 These mutants cannot sustain ubiquitin-dependent proteolysis even though neither moti

235 g hypoxia-inducible factor-alpha subunits to ubiquitin-dependent proteolysis has been well documented

236 Ubiquitin-dependent proteolysis is an important mechanis

237 to the nucleus in G(1) phase, but undergoes ubiquitin-dependent proteolysis later in cell cycle.

238 Ubiquitin-dependent proteolysis makes a major contributi

239 ciated links between fatty acid synthase and ubiquitin-dependent proteolysis of cell-cycle regulatory

240 Ubiquitin-dependent proteolysis of cyclin D1 is associat

241 we characterized the enzymes involved in the ubiquitin-dependent proteolysis of E7.

242 multiprotein E3 ubiquitin ligase involved in ubiquitin-dependent proteolysis of key cell cycle regula

243 Ubiquitin-dependent proteolysis of p27(kip1) is growth a

244 , also known as the cyclosome) regulates the ubiquitin-dependent proteolysis of specific cell-cycle p

245 By triggering the appropriately timed, ubiquitin-dependent proteolysis of the mitotic regulator

246 -based E3 ubiquitin ligase that promotes the ubiquitin-dependent proteolysis of various substrates im

247 Ubiquitin-dependent proteolysis plays an important role

248 Ubiquitin-dependent proteolysis regulates gene expressio

249 odified proteins and that failure to execute ubiquitin-dependent proteolysis renders various cell typ

250 ntial susceptibility of the catalytic LCs to ubiquitin-dependent proteolysis therefore might explain

251 level of E7 in cancer cells is regulated by ubiquitin-dependent proteolysis through the 26S proteaso

252 As such, TRF1 levels are regulated by ubiquitin-dependent proteolysis via an SCF E3 ligase whe

253 tes, stabilization of typical substrates for ubiquitin-dependent proteolysis, and enhanced susceptibi

254 etwork of proteins that function together in ubiquitin-dependent proteolysis, and the UBL method offe

255 ver, Lys(6)-biotinylated ubiquitin inhibited ubiquitin-dependent proteolysis, as conjugates formed wi

256 le without showing obvious signs of impaired ubiquitin-dependent proteolysis, indicating that other d

257 n the established role of the RUB pathway in ubiquitin-dependent proteolysis, these data suggest that

258 rogression and postmitotic processes through ubiquitin-dependent proteolysis.

259 Many proteins are regulated by ubiquitin-dependent proteolysis.

260 d negatively regulates Ira2 by promoting its ubiquitin-dependent proteolysis.

261 h F-box-binding protein beta-TrCP, undergoes ubiquitin-dependent proteolysis.

262 criptional activity and targets ER alpha for ubiquitin-dependent proteolysis.

263 dulate multiple biological processes through ubiquitin-dependent proteolysis.

264 due to accelerated protein breakdown through ubiquitin-dependent proteolysis.

265 transcription factors, is regulated through ubiquitin-dependent proteolysis.

266 Substrates of a ubiquitin-dependent proteolytic system called the N-end

267 rate for the N-end rule pathway, which is an ubiquitin-dependent proteolytic system in which the iden

268 t proteins for destruction by exploiting the ubiquitin-dependent proteolytic system of eukaryotic cel

269 e is a part of the Arg/N-end rule pathway, a ubiquitin-dependent proteolytic system.

270 TCDD also increased acetylation and ubiquitin-dependent proteosomal degradation of the perox

271 rols cell surface Cav1.3 levels by promoting ubiquitin-dependent proteosomal degradation.

272 followed by its subsequent degradation by an ubiquitin-dependent quality control pathway called RADAR

273 We conclude that ubiquitin-dependent regulation of translation is an impo

274 lded ER-resident proteins is well described, ubiquitin-dependent regulation of translational reprogra

275 rs is a highly dynamic process that involves ubiquitin-dependent regulation.

276 f SAG-CUL1-FBXW7 E3 ligase and establishes a ubiquitin-dependent regulatory mechanism for the NF1-RAS

277 the plant includes protein interactions and ubiquitin-dependent repressor degradation.

278 We conclude that the ubiquitin-dependent sculpting of the chromosomal distrib

279 l conditions, might be sufficient to trigger ubiquitin-dependent sequestration of partially misfolded

280 ism for the integrated regulation of diverse ubiquitin-dependent signaling pathways through E2 phosph

281 ntly been developed to dissect mechanisms of ubiquitin-dependent signaling, thereby revealing the cri

282 biquitin to target proteins thereby enabling ubiquitin-dependent signaling.

283 er, which is contrary to the current idea of ubiquitin-dependent sorting of proteins to exosomes.

284 functions at the endosome, which oppose the ubiquitin-dependent sorting of receptors to lysosomes.

285 vealed by observation of UbcH7 approximately ubiquitin-dependent substrate inhibition of chain format

286 Degradation of a ubiquitin-dependent substrate was restored by the rpt2(E

287 ochondrial division is regulated by a MARCH5 ubiquitin-dependent switch.

288 The N-end rule pathway is a ubiquitin-dependent system where E3 ligases called N-rec

289 Degradation of p27(Kip1) is mediated by ubiquitin-dependent targeting of p27(Kip1) by SCF -Skp2.

290 al protein stability, possibly by preventing ubiquitin-dependent targeting of viral proteins for dest

291 ially lower processivity of degradation than ubiquitin-dependent targeting.

292 ate (HRS) was characterized as necessary for ubiquitin-dependent TLR9 targeting to the endolysosome.

293 activity is dependent upon NEDD8, Cif blocks ubiquitin dependent trafficking of Perforin-2 and thus,

294 critical induction events involve changes in ubiquitin-dependent trafficking of MHC-II and CD86 by th

295 Although ubiquitin-dependent trafficking of MHC-II has been well

296 novel E3 ligase that specifically regulates ubiquitin-dependent trafficking of pAKT in insulin-like

297 at is reminiscent of, yet distinct from, the ubiquitin-dependent transactivation of the oncoprotein M

298 etylation in the presence of T3 and enhances ubiquitin-dependent TRbeta1 turnover; a common response

299 activity that may be due in part to reduced ubiquitin-dependent turnover of PKCalpha.

300 nhance zinc secretion and then by activating ubiquitin-dependent ZnT2 degradation.