ライフサイエンスコーパス: ultrastructural

1 ted fixation followed by photoconversion and ultrastructural 3D analysis, we tracked endocytic vesicl

2 e model of Down syndrome, demonstrating that ultrastructural abnormalities and impaired short-term pl

3 ies/field, respectively; P < .05), with mild ultrastructural abnormalities in the remaining ICCs.

4 in mice induces muscle fibre remodelling and ultrastructural abnormalities including ringed fibres, s

5 cholestasis, mild-to-moderate fibrosis, and ultrastructural abnormalities of bile canaliculi.

6 ized by steatosis, death of hepatocytes, and ultrastructural abnormalities of endoplasmic reticulum a

7 ar tachycardia in treated mice, (3) reverted ultrastructural abnormalities of junctional sarcoplasmic

8 Six ultrastructural abnormalities were identified including

9 Gata6-deficient beta-cells exhibit ultrastructural abnormalities, including increased immat

10 opment of heart failure, suggesting residual ultrastructural abnormalities.

11 respiratory chain deficiency, mitochondrial ultrastructural alterations and fragmentation of the mit

12 5 were measured by immunohistochemistry, and ultrastructural alterations in intestinal epithelial cel

13 This study reveals a correlation between ultrastructural alterations of DM in donor corneas and t

14 histopathologic signs of myopathy and showed ultrastructural alterations of mitochondria and sarcopla

15 nvestigate at nanometer scale resolution the ultrastructural alterations of the glomerular filtration

16 embrane may provide a way to detect possible ultrastructural alterations of the hair cell stereocilia

17 Diabetic MPs (D-MPs) display ultrastructural alterations, a differentiation bias towa

18 a, nephromegaly, hyperfiltration, glomerular ultrastructural alterations, and aberrant angiogenesis.

19 leukin-15 than controls; their IECs also had ultrastructural alterations.

20 Ultrastructural analyses and live imaging demonstrate th

21 Ultrastructural analyses at P20 by transmission electron

22 Ultrastructural analyses demonstrated abnormal stratum c

23 Immunohistochemical and ultrastructural analyses demonstrated that alpha-synucle

24 these differences, we performed quantitative ultrastructural analyses of glomeruli in rat olfactory b

25 Immunofluorescence and ultrastructural analyses of muscle end-plate regions sho

26 Ultrastructural analyses revealed a decrease in spine he

27 Ultrastructural analyses revealed a marked reduction in

28 Histopathological and ultrastructural analyses revealed that liver, lung and h

29 Ultrastructural analyses revealed that the luminal pocke

30 However, morphometric and ultrastructural analyses show an altered shape of nodes

31 Remarkably, ultrastructural analyses showed that Talpid3 is required

32 Biochemical and ultrastructural analyses showed that the organelles in t

33 emistry for rabbit IgG and THSD7A as well as ultrastructural analyses showed the typical characterist

34 Here we used biochemical and ultrastructural analyses to generate a temporospatial ma

35 , we used genetic, electrophysiological, and ultrastructural analyses to probe the architecture of ri

36 ICCs were counted and ultrastructural analyses were performed on tissue sample

37 w tissues according to rigorous quantitative ultrastructural analyses, but did affect cell and tissue

38 vitro experiments of vascular reactivity and ultrastructural analyses, we demonstrate that PTX3 induc

39 dy, by combining immunohistochemistry and 3D ultrastructural analyses, we show that mitochondrial fis

40 This was consistent with ultrastructural analyses, which showed that the aggregat

41 culum stress, as revealed by biochemical and ultrastructural analyses.

42 Ultrastructural analysis also revealed the presence of H

43 Ultrastructural analysis by electron and superresolution

44 uired for mitochondrial gene expression, and ultrastructural analysis confirmed compromised mitochond

45 Ultrastructural analysis demonstrated a direct synaptic

46 Ultrastructural analysis demonstrated elongated and thin

47 Ultrastructural analysis demonstrates that miR-8 is requ

48 Ultrastructural analysis further reveals characteristic

49 Ultrastructural analysis in RSPH1-mutated cilia revealed

50 In general, our ultrastructural analysis methods could be useful for a w

51 h tagged envelope glycoproteins that enabled ultrastructural analysis of affinity-purified virions.

52 Biophysical and ultrastructural analysis of AVNFH bone revealed increase

53 Ultrastructural analysis of CA1 hippocampal synapses sho

54 We performed a quantitative ultrastructural analysis of cortical excitatory synapses

55 e first, to our knowledge, three-dimensional ultrastructural analysis of membrane-bound VRCs of a pla

56 Ultrastructural analysis of MMP-3 treated matrices by tr

57 Ultrastructural analysis of neuronal nuclei after 70 wee

58 by using flow cytometry, and histologic and ultrastructural analysis of patient tissues.

59 Ultrastructural analysis of SBMA mice revealed a block i

60 Quantitative ultrastructural analysis of SynCAM 1 KO retina measured

61 This study presents the first ultrastructural analysis of the capillaries constituting

62 vertebrate synapse and performed a detailed ultrastructural analysis of the effects on presynaptic m

63 At this time, ultrastructural analysis of the sciatic nerve showed de-

64 Histopathologic and ultrastructural analysis of these epiretinal proliferati

65 Ultrastructural analysis of Vps33b(fl/fl)-ER(T2) platele

66 Ultrastructural analysis of yeast cells using electron m

67 Ultrastructural analysis revealed discrete extranuclear

68 Ultrastructural analysis revealed improvement of sarcome

69 Ultrastructural analysis revealed labeled retinal termin

70 Ultrastructural analysis revealed submembranous localiza

71 Ultrastructural analysis revealed that chelerythrine-med

72 Ultrastructural analysis revealed that large vesicles ar

73 Ultrastructural analysis revealed that luminal calcium d

74 Ultrastructural analysis revealed that mutant tanycytes

75 Ultrastructural analysis revealed that these terminals,

76 Ultrastructural analysis reveals an extensive ER network

77 However, ultrastructural analysis reveals that nuclear disassembl

78 Ultrastructural analysis showed intraislet phagocytes co

79 High-resolution ultrastructural analysis showed that CD44 was localized

80 Additionally, ultrastructural analysis showed that cGKII knockdown or

81 Consistent with the light microscopic data, ultrastructural analysis showed that the number of ChAT(

82 Ultrastructural analysis shows actin accumulation at the

83 Ultrastructural analysis shows that removal of the cytop

84 Ultrastructural analysis shows that these two factors to

85 RNA-sequencing, ultrastructural analysis, and in vitro progenitor assays

86 By combining trans-synaptic labeling, ultrastructural analysis, calcium imaging, optogenetics

87 Using ultrastructural analysis, we show that these patient-der

88 gallus) with neural tracers and performed an ultrastructural analysis.

89 on these biofilms by colorimetric assay and ultrastructural analysis.

90 survival times both in semithin sections and ultrastructural analysis.

91 elin protein expression, immunostaining, and ultrastructural analysis.

92 philic esophagitis biopsy specimens based on ultrastructural analysis.

93 Ultrastructural and confocal microscopy of P. gingivalis

94 al lipids and inner monolayer lipids, and by ultrastructural and confocal microscopy studies.

95 Ultrastructural and functional analyses indicate that LD

96 Here, we use a combined ultrastructural and functional analysis to examine the r

97 The combined use of ultrastructural and functional studies has greatly incre

98 Lung disease was heterogeneous across all ultrastructural and genotype groups, but worse in those

99 termined in the contralateral hemisphere via ultrastructural and immunohistochemical analyses.

100 ion of skeletal muscle myosin and the normal ultrastructural and mechanical properties of muscle.

101 Ultrastructural and molecular characterisation shows tha

102 ons (AVLs), and geographic atrophy (GA); and ultrastructural and staining characteristics of druse su

103 iculus (tectogeniculate) possess many of the ultrastructural and synaptic properties that define driv

104 synaptic branching and enlarge boutons, with ultrastructural and synaptic reconstitution MB connectiv

105 eurons found in the cat display morphologic, ultrastructural, and connectional differences suggesting

106 in the developing brain, we used anatomical, ultrastructural, and electrophysiological techniques to

107 Anatomical, ultrastructural, and functional studies indicate that th

108 ught to understand the behavioral, cellular, ultrastructural, and molecular changes that occur at a p

109 r drusen typically demonstrated a homogenous ultrastructural appearance similar to hard drusen, where

110 Ultrastructural appearances distinguish dense deposit di

111 This article shows the ultrastructural architecture of larval zebrafish (Danio

112 nerated stresses and depends strongly on the ultrastructural architecture of the network.

113 ies in gene expression, morphology, collagen ultrastructural arrangement and developmental regulation

114 onic system, and provides the functional and ultrastructural basis for its application to human skele

115 Here, ultrastructural, biophysical, and computational analyses

116 surface by scanning electron microscopy and ultrastructural capsular remnants by transmission electr

117 oxygen species and glutathione contents, and ultrastructural cellular damages were studied in the hum

118 racture electron microscopy, we resolved the ultrastructural change in the claudin-1-induced SD-TJ tr

119 levels, compromised barrier function, marked ultrastructural change, and enhanced dehydration suscept

120 (n = 5 rats per group); and 3) the cortical ultrastructural changes after treatment (n = 1 per group

121 Down-regulation of the aret gene led to ultrastructural changes and functional impairment of fli

122 ncreases the rate of greening and stimulates ultrastructural changes characteristic for the etioplast

123 After bortezomib treatment, they showed ultrastructural changes characteristic of endoplasmic re

124 emmal complexes, sarcolemmal disruption, and ultrastructural changes characteristic of human MDs and

125 Furthermore, we found striking ultrastructural changes in glomerular basement membranes

126 Mc4r cardiomyopathy is characterized by ultrastructural changes in mitochondrial morphology and

127 ice induced behavioral, transcriptional, and ultrastructural changes in oligodendrocytes of the prefr

128 itamin D supplementation also prevented some ultrastructural changes in response to bleomycin adminis

129 d by the reduction of presynaptic vGlut1 and ultrastructural changes in the perisynaptic space.

130 In conclusion, the histologic and ultrastructural changes of cementum and alveolar bone mi

131 s within neuroscience, little is known about ultrastructural changes of synaptic morphology during ag

132 hanced understanding of the pathogenesis and ultrastructural changes of the condition, and in turn ha

133 ed proinflammatory mediators and significant ultrastructural changes to the host cells.

134 Morphological and ultrastructural changes were observed in islets of Lange

135 ch of the trigeminal nerves, led to synaptic ultrastructural changes when the injured animals have de

136 s, optimal therapeutic strategies to prevent ultrastructural changes, and long-term risk of sudden de

137 ulmonary fibrosis by delaying or suppressing ultrastructural changes, as well as attenuating hydroxyp

138 ssion at BC-->GC synapses is attributable to ultrastructural changes.

139 y member carrying the gene variant to assess ultrastructural changes.

140 pitomonas bilix is intriguing, since several ultrastructural characteristics implied its evolutionary

141 Although the ultrastructural characteristics of cuticular drusen appe

142 ith greater axodendritic synapse density and ultrastructural characteristics of enhanced synaptic eff

143 the mitochondria-located NDUFAF6 isoform and ultrastructural characteristics of mitochondrial dysfunc

144 technology to examine the three-dimensional ultrastructural characteristics of proteinuric glomerulo

145 esolution to uncover and rediscover critical ultrastructural characteristics of the glomerulopathy in

146 alendronate and elucidate the histologic and ultrastructural characteristics of the microcalcificatio

147 phagosomes, endogenous levels of LC3-II, and ultrastructural characteristics typical of autophagosome

148 Here, we report the ultrastructural characterization of self-propagating Sup

149 However, the functional and ultrastructural characterization, which is crucial for d

150 riched by filtration for coupled genomic and ultrastructural characterization.

151 -19 cis interaction increase tight junction ultrastructural complexity but reduce tight junction per

152 n et al. address this question by forming an ultrastructural "connectome" of the mouse's visual thala

153 TA), lesion volumes, and global white matter ultrastructural damage indexed as increased mean diffusi

154 fluency performance, lesion topography, and ultrastructural damage were assessed with voxel-based st

155 Integration with ultrastructural data for recombination nodules further r

156 Surprisingly, ultrastructural data indicated that overexpression led t

157 hin the same fibrils, in good agreement with ultrastructural data.

158 ildhood primary ciliary dyskinesia (PCD) and ultrastructural defects and genotype is poorly defined.

159 terogeneity, associated with different cilia ultrastructural defects and mutations identified in >20

160 Following a systematic literature review on ultrastructural defects in mitochondrial myopathy, we in

161 Whereas minor retinal ultrastructural defects were observed at all ages examin

162 GN1-mutant granulocytes are characterized by ultrastructural defects, a paucity of granules, aberrant

163 nction, there were substantive mitochondrial ultrastructural defects, ineffective superoxide scavengi

164 e groups, but worse in those with IDA/CA/MTD ultrastructural defects, most of whom had biallelic muta

165 This complete ultrastructural description of diverse cilia in C. elega

166 nica goes beyond gross morphology to include ultrastructural details and labile molecular components

167 show that the eyes of Tullimonstrum possess ultrastructural details indicating homology with vertebr

168 Improved ultrastructural detection of lipids and correlative ligh

169 Here we describe a protocol for ultrastructural detection of proteins in leukocytes.

170 ate synapse growth, structural architecture, ultrastructural development and functional differentiati

171 levels in testes, and impaired motility and ultrastructural disorganization of spermatozoa.

172 ynaptic effects of Chmp2b, we determined its ultrastructural distribution by quantitative immuno-elec

173 the EDM was nearly absent, whereas the other ultrastructural elements in the mechanosensitive organel

174 ygous mutant mice exhibited histological and ultrastructural epithelial cell fragility phenotypes.

175 An ultrastructural evaluation of glomeruli from animals wit

176 Electron microscopy ultrastructural evaluation, cardiomyocyte glycogen conte

177 This was mirrored by ultrastructural evidence of Ca(2+) release units, which

178 been obtained by functional studies, whereas ultrastructural evidence of synaptic contacts is scarce.

179 These results provide ultrastructural evidence suggestive of somatic endomembr

180 ective promoter PRSx8 and obtained light and ultrastructural evidence that these neurons innervate th

181 Ultrastructural examination indicated that disc formatio

182 Ultrastructural examination of dislocated lenses and exc

183 Ultrastructural examination of midgut epithelial cells r

184 Ultrastructural examination of podocytes confirmed more

185 Ultrastructural examination using transmission electron

186 Importantly, ultrastructural examinations of such DNs revealed gradua

187 Retrograde and ultrastructural examinations reveal that the core of the

188 PSD ultrastructural features are also conserved.

189 The diversity of synaptic ultrastructural features demonstrated here have broad im

190 villus-like projections (VP); however, these ultrastructural features have not been systematically st

191 The ultrastructural features in ex vivo human capsulotomy sp

192 To investigate the ultrastructural features of anterior capsulotomy perform

193 No caspase activation or ultrastructural features of apoptotic cell death were ob

194 Our results define specific ultrastructural features of E-Syt-dependent ER-PM contac

195 sed serial electron microscopy to assess the ultrastructural features of excitatory (asymmetric) syna

196 lectron microscopic analyses revealed unique ultrastructural features of lanceolate complexes that ar

197 his approach exhibits the major cellular and ultrastructural features of native in vivo human dermal

198 found that DREAM deletion does not alter the ultrastructural features of platelets but significantly

199 Ultrastructural features of PPC and presence of irregula

200 Ultrastructural features potentially related to cell and

201 proach elucidates which infection-associated ultrastructural features represent bona fide HIV protein

202 ed objects observed in light microscopy with ultrastructural features seen by electron microscopy in

203 sarcomas demonstrate immunohistochemical and ultrastructural features typical of this lineage, they v

204 high density for super-resolution imaging of ultrastructural features within cells.

205 se cones express rod transducin and have rod ultrastructural features, providing strong support for t

206 asinococcales clade, characterized by unique ultrastructural features, warrants recognition of a new

207 he histopathologic, immunohistochemical, and ultrastructural findings from the first autopsy performe

208 spectrometry (SIMS) with the high-resolution ultrastructural images obtained using electron microscop

209 lds, are rapidly becoming powerful tools for ultrastructural imaging of biological samples.

210 Further, ultrastructural imaging of the treated tumors revealed t

211 el studies using genome-wide RNA sequencing, ultrastructural imaging, and whole-cell recording in wil

212 sel density was increased without changes in ultrastructural imaging.

213 Ultrastructural immunocytochemistry confirmed the presen

214 h increased oxidative stress and significant ultrastructural impairment of mitochondrial morphology w

215 to recapitulate the human MSM phenotype with ultrastructural inclusions, suggesting that the diminish

216 he utility of SMLM in efficiently uncovering ultrastructural information of archived clinical samples

217 Here we outline a procedure for ultrastructural investigation of functional vesicles in

218 continue to be elucidated by biochemical and ultrastructural investigations.

219 of neuronal morphology is not studied at the ultrastructural level in CM.

220 ICAM-5 has not been explored in depth at the ultrastructural level in intact brain tissue.

221 ects of motor rehabilitative training at the ultrastructural level in peri-infarct motor cortex.

222 At the ultrastructural level, defects were observed in endosoma

223 However, at the ultrastructural level, FS-->SP synapses in deprived hemi

224 To visualize synaptic contacts at the ultrastructural level, we develop and apply a "two-tag"

225 At the ultrastructural level, we observed formation of axonal s

226 described the underlying abnormalities on an ultrastructural level.

227 elative light and electron microscopy at the ultrastructural level.

228 toskeleton simultaneously, especially at the ultrastructural level.

229 orrelating with ribosome distribution at the ultrastructural level.

230 atomical pathways that express NMUR2 and its ultrastructural localization are unknown.

231 Ultrastructural localization of endogenous ligands suppo

232 To investigate the ultrastructural localization of ICAM-5 with transmission

233 Our aims were to determine the ultrastructural location of polySia in the NTS and the f

234 se mutations in this DST isoform that led to ultrastructural loss of hemidesmosomal inner plaques and

235 agmentation of the mitochondrial network and ultrastructural major abnormalities including loss, diso

236 In particular, no data are available on the ultrastructural mapping of these proteins in the calcifi

237 Through electrophysiological and ultrastructural measurements, we calculated release site

238 g of sea cucumber dermis, we investigate the ultrastructural mechanics of MCT by measuring fibril str

239 y for deeper investigations of the molecular ultrastructural mechanisms involved in action potential

240 We investigated molecular and ultrastructural mechanisms of bacterial endocytosis, foc

241 Structural, ultrastructural, microstructural, metabolic, molecular,

242 cardiac and neuronal NaV isoforms and their ultrastructural milieu have important implications for t

243 Ultrastructural mitochondrial changes were consistent wi

244 We propose an ultrastructural model of mycobacterial polar growth wher

245 low (LT) or high (HT) temperature drying on ultrastructural, molecular and in vitro digestibility pr

246 ltrating lymphocytes and cells that have the ultrastructural morphologic characteristics of dendritic

247 Optical coherence tomography, semithin, ultrastructural morphology and assessment of inflammator

248 itation) and mass spectrometry), CA1 synapse ultrastructural morphology, and synaptic functioning in

249 Here, we tested this model by analyzing the ultrastructural morphology, kinetics of cargo transport,

250 t-like staining pattern that correlates with ultrastructural morphology.

251 dney disease, based on meticulously acquired ultrastructural morphometry and the utility of measuring

252 Ultrastructural morphometry revealed that Syt1-RQ fully

253 Ultrastructural observation of tsp-2 and tsp-3 dsRNA-tre

254 Our ultrastructural observations shed light on possible func

255 s and transcriptomics studies, together with ultrastructural observations, suggest that more than one

256 The ultrastructural organization of the blood labyrinthine b

257 ative electron microscopy revealed unaltered ultrastructural parameters.

258 re's disease specimens revealed differential ultrastructural pathological changes in the cellular ele

259 Previously unreported ultrastructural patterns in the cornea were noted: large

260 lution imaging and specific histological and ultrastructural patterns in type II focal cortical dyspl

261 The ultrastructural patterns were also distinct.

262 cal, histopathologic, immunofluorescent, and ultrastructural phenotype and to identify the underlying

263 protofilament packing, showing that they are ultrastructural polymorphs.

264 Here we present an optimized protocol for ultrastructural preparation of S. mediterranea.

265 F/FS because this allows for close-to-native ultrastructural preservation.

266 for the human allele displayed disorganized ultrastructural properties of the aortic wall characteri

267 Ultrastructural, proteomic and FACS analyses of Atg16L-p

268 n-GFP transgenic mice and provide a detailed ultrastructural reconstruction analysis of Nestin-GFP-po

269 Combining selective ultrastructural reconstruction of neuropil with function

270 A three-dimensional, ultrastructural reconstruction, based on correlative lig

271 formation, however complex three-dimensional ultrastructural relationships between cells and their ex

272 on electron microscopy images also showed no ultrastructural remodeling for failing vs. donor mitocho

273 in an ovine tachypacing-induced HF model and ultrastructural remodeling of the ICD by determining the

274 CS-exposed mice, we assessed pathologic and ultrastructural renal lesions, and measured urinary albu

275 relation of immunofluorescence data with the ultrastructural resolution of scanning electron microsco

276 ce revealed high-frequency hearing loss, and ultrastructural scanning electron microscopy analyses of

277 oscopy, we monitored fibril formation at the ultrastructural, secondary conformational, and local lev

278 Biopsies with glomerulitis showed ultrastructural signs of glomerular capillary wall remod

279 l associations, which were first observed in ultrastructural studies decades ago.

280 Early ultrastructural studies have revealed the presence of "g

281 These findings contrast with previous ultrastructural studies in monkey DLPFC where Type I PV-

282 Ultrastructural studies indicated that both wild-type an

283 Marker, time-lapse and ultrastructural studies indicated that oligodendrocyte s

284 Histological and ultrastructural studies indicated that the cV-SVZ is org

285 Ultrastructural studies of the glomerulus by transmissio

286 e clamp-like structures observed in previous ultrastructural studies of the phloem and shows that the

287 For example, ultrastructural studies of vesicle transport were aided

288 Ultrastructural studies revealed that after preincubatio

289 Our ultrastructural studies show that in cones, OS formation

290 Ultrastructural studies show that the glomerular basemen

291 Ultrastructural studies showed numerous larger-sized and

292 Ultrastructural studies suggest that these coats assembl

293 Ultrastructural studies uncovered progressive dilation o

294 The ultrastructural study showed that the strong signal hype

295 have been developed for S. mediterranea, but ultrastructural techniques have received far less attent

296 characterised by early onset proteinuria and ultrastructural thickening and splitting of the glomerul

297 er ischemic lesion locations and severity of ultrastructural tract damage contribute to cognitive imp

298 Analyses of multiple ultrastructural variables revealed four organizational f

299 gle synchrotron X-ray scattering revealed an ultrastructural variation (orientation, particle size, a

300 ved in diabetic hyperfiltration, focusing on ultrastructural, vascular, and tubular factors.