ライフサイエンスコーパス: unacceptably

1 e pro-drug depends on (a) elimination of the unacceptably bitter taste of free erythromycin, (b) its

2 e against women by intimate partners remains unacceptably common worldwide.

3 and recurrences of cutaneous lesions remain unacceptably frequent among survivors of neonatal herpes

4 he many forms of child maltreatment exact an unacceptably heavy toll on our children.

5 nistic fungal infections continue to take an unacceptably heavy toll on the most disadvantaged living

6 , the incidence of anastomotic leaks remains unacceptably high ( approximately 10%) even when perform

7 valence of stunting and underweight remained unacceptably high (30.0%, 95% CI 27.0-33.0, for stunting

8 situation where the rate of misdiagnosis is unacceptably high (up to 43%).

9 miting neutropenia and thrombocytopenia were unacceptably high after the doses of either TPT or PTX-2

10 man papillomavirus-associated anal cancer is unacceptably high among HIV-positive men who have sex wi

11 d mortality for high-risk older patients was unacceptably high and abrogated the reduction in relapse

12 Mortality in sepsis remains unacceptably high and attempts to modulate the inflammat

13 th penicillin and ampicillin disk tests were unacceptably high and precluded recommended testing of t

14 evere diarrhea and/or cutaneous toxicity was unacceptably high at OSI-774 doses exceeding 150 mg/d.

15 rate of severe myelosuppressive effects was unacceptably high at TMZ doses exceeding 150 mg/m(2)/d i

16 rstitial and malignant lung diseases remains unacceptably high because control measures are not imple

17 a venous thrombosis rate that was considered unacceptably high by the study oversight committee (thro

18 This results in unacceptably high costs for exhaustive genotyping and pr

19 Mortality from cardiogenic shock remains unacceptably high despite early coronary revascularizati

20 not acceptable (50%) and their recipient had unacceptably high donor-specific antibodies (28%).

21 ors were unacceptable, and 22 recipients had unacceptably high donor-specific antibodies.

22 market exclusivity has been associated with unacceptably high drug costs, both for newly developed d

23 wildlife, and (4) surface impoundments pose unacceptably high ecological risks regardless of locatio

24 the inbreeding loads considered, CM leads to unacceptably high extinction risks and, as a result, to

25 equired for metagenome sequencing has led to unacceptably high false discovery rates (FDR).

26 However, unacceptably high false-negative rates have been reporte

27 tivity, SN examination resulted in either an unacceptably high false-positive rate (20%) or a low sen

28 (NCNs) in 24-50% of subjects, suggesting an unacceptably high false-positive rate.

29 Lower thresholds resulted in unacceptably high false-positive rates (ie, cysts that a

30 ositive, error rates between BMD and DD were unacceptably high for ampicillin-sulbactam (VM error, 9.

31 eover, plasmapheresis was associated with an unacceptably high frequency of infectious complications.

32 Blood pressure levels remain unacceptably high in about half of such patients.

33 Incidence densities in MSM are unacceptably high in countries as diverse as China, Keny

34 often associated with thrombocytopenia, was unacceptably high in HP and MP patients treated at 572 m

35 Mortality from severe malaria remains unacceptably high in sub-Saharan Africa.

36 for pediatric heart transplantation remains unacceptably high in the current era.

37 t the recommended dose is associated with an unacceptably high incidence of AE; in such patients, the

38 fecting women of childbearing age, causes an unacceptably high incidence of irreversible premature ov

39 Removal of less than 3.5 glands has an unacceptably high incidence of persistent HPT (42%), whe

40 hat were withdrawn from the market due to an unacceptably high incidence of severe hepatotoxicity.

41 Due to unacceptably high interlaboratory variation in caspofung

42 ceptibility of Candida to caspofungin due to unacceptably high interlaboratory variation of caspofung

43 Tuberculosis incidence is unacceptably high irrespective of HIV status in black Af

44 mponents, the generated heat loads result in unacceptably high junction temperatures and reduced comp

45 um) cultivars and can result in commercially unacceptably high levels of alpha-amylase in harvest-rip

46 d (minor error rate, 63.6%) methods produced unacceptably high levels of errors when testing penicill

47 nately, however, these optodes suffered from unacceptably high levels of sodium interference under ph

48 lay of 24 h prior to adding to UPT led to an unacceptably high loss of assay sensitivity.

49 are providers and healthcare institutions at unacceptably high malpractice risk?

50 ningitis remains a devastating disease, with unacceptably high morbidity and mortality despite advanc

51 of the CARRS score identifies patients with unacceptably high mortality after HTx and those with a s

52 Renal ischemic reperfusion injury results in unacceptably high mortality and morbidity during the per

53 rbidity worldwide and are associated with an unacceptably high mortality despite the availability of

54 ently below 15 mL/min per 1.73 m(2)--have an unacceptably high mortality rate.

55 ition, which continues to be associated with unacceptably high mortality.

56 nt pathways and interventions to address the unacceptably high mortality.

57 HIV-infected patients with MDR-TB have unacceptably high mortality; both antiretroviral and ant

58 ificantly more false-positive results and an unacceptably high number of indeterminate results.

59 nual retinal exams for diabetes patients, an unacceptably high number of patients are not screened fo

60 terminate the trial if the toxicity rate is unacceptably high or the complete remission (CR) rate is

61 In an unacceptably high percentage of these patients, variabil

62 otease inhibitors as monotherapy has been an unacceptably high rate of emergence of resistance.

63 ove baseline, but also was accompanied by an unacceptably high rate of endometrial hyperplasia.

64 d to exhaustion and thereby contribute to an unacceptably high rate of intermediate and long-term gra

65 vudine regimen resulted in an unexpected and unacceptably high rate of nonresponse and incidence of K

66 t seven patients were enrolled because of an unacceptably high rate of rejection (7/7 = 100%).

67 se lower safety margins were associated with unacceptably high rates of failed defibrillation and sud

68 response to infection and is associated with unacceptably high rates of mortality and morbidity.

69 r, patients with high-risk tumors still have unacceptably high rates of recurrence and disease progre

70 to current cytotoxic chemotherapy and suffer unacceptably high rates of relapse, supporting the need

71 HP patients, with higher doses resulting in unacceptably high rates of severe hematologic toxicity.

72 by local excision alone are associated with unacceptably high recurrence rates.

73 ependent data monitoring committee due to an unacceptably high relapse rate in the PET-negative patie

74 Due to the unacceptably high risk for mortality from open heart sur

75 t extracts is not recommended because of the unacceptably high risk of anaphylaxis.

76 use of anticoagulants may be associated with unacceptably high risk of bleeding complications.

77 diverse compounds bind to hERG and carry an unacceptably high risk of causing arrhythmias.

78 m fungal cultures are uncommon, but carry an unacceptably high risk of postoperative fungal infection

79 but 80 mg simvastatin is associated with an unacceptably high risk of statin-induced myopathy.

80 uld be given in limiting its use to cases of unacceptably high risk of stroke during aortic cross-cla

81 procedures are particularly associated with unacceptably high short and long-term morbidity and mort

82 ion that younger and smaller infants face an unacceptably high surgical risk.

83 or China to intensify efforts for those with unacceptably high under-5 mortality rates.

84 L PICC design used in this study resulted in unacceptably high venous thrombosis rates.

85 This has created unacceptably high waiting-list mortality for lung transp

86 h oral squamous cell carcinoma (OSCC) remain unacceptably high with disfiguring treatment options and

87 Although mortality in all groups remains unacceptably high, additional emphasis should be placed

88 tality and morbidity after lung resection is unacceptably high, and has changed little in the last 20

89 sepsis-induced acute kidney injury (AKI) is unacceptably high, especially in the elderly.

90 the probability of sign inconsistency can be unacceptably high, even when the conditions for QTL dete

91 y rate for acute kidney injury (AKI) remains unacceptably high, likely owing to extrarenal organ dysf

92 sub-Saharan Africans, maternal mortality is unacceptably high, with >400 deaths per 100,000 births c

93 ne report delayed nausea, the proportion was unacceptably high.

94 th chloroquine+sulfadoxine-pyrimethamine was unacceptably high.

95 Mortality rates in ESRD are unacceptably high.

96 hat the morbidity and mortality rates remain unacceptably high.

97 e incidence of acute rheumatic fever remains unacceptably high.

98 ever, the rate of distant metastasis remains unacceptably high.

99 and the rate of progression to ESRD remained unacceptably high.

100 ates of heart failure hospitalization remain unacceptably high.

101 enting cells, making potential vaccine costs unacceptably high.

102 economic burden of heart failure (HF) remain unacceptably high.

103 prescribing in dementia in Scotland remains unacceptably high.

104 ents with acute liver failure (ALF) is still unacceptably high.

105 anticancer drugs entering clinical trials is unacceptably high.

106 ular failure; morbidity and mortality remain unacceptably high.

107 n high-prevalence settings in Africa remains unacceptably high.

108 e of aligner, the rate of false positives is unacceptably high.

109 th mean and SD in these circumstances may be unacceptably high.

110 ients with acute renal failure (ARF) remains unacceptably high.

111 e residual disability and death rate remains unacceptably high.

112 eas--including immunosuppressant use--appear unacceptably high.

113 ence in the population at large has remained unacceptably high.

114 llbirths remains unchanged since 2011 and is unacceptably high: an estimated 2.6 million in 2015.

115 therapeutic efficacy of a new therapy is not unacceptably inferior to that of standard therapy are ca

116 for some individuals sulfur gases can cause unacceptably large (up to 500%) errors, making the sulfu

117 distribution of origins would generate some unacceptably large interorigin distances.

118 ly structural lead (1f, SC-236) exhibited an unacceptably long plasma half-life, a number of pyrazole

119 equipment and infrastructure requirements to unacceptably long turnaround times.

120 high or the complete remission (CR) rate is unacceptably low compared with the rates of these events

121 ed as a technically demanding procedure with unacceptably low efficiency using either contemporary tr

122 assays in individuals presenting for PEP is unacceptably low for bDNA-based testing and possibly acc

123 nkton; however, the signal-to-noise ratio is unacceptably low in extremely oligotrophic regions, whic

124 are not water soluble and consequently have unacceptably low oral bioavailabilities.

125 ely difficult to treat successfully, and the unacceptably low overall survival rates mandate that we

126 while yielding a rapid in-office result, had unacceptably low sensitivity.

127 l applications of gene delivery, albeit with unacceptably low transfection efficiencies (TE).

128 sensitivities of the toxin immunoassays were unacceptably low, while the LightCycler real-time PCR as

129 Us based on risk-adjusted mortality rate was unacceptably low.

130 quently, worldwide access to radiotherapy is unacceptably low.

131 treatment for children with malaria remains unacceptably low.

132 0% was desired, and 80% was considered to be unacceptably low.

133 effective, and current utilization rates are unacceptably low.

134 rates for patients with advanced CRC remain unacceptably low.

135 lly or morphologically defined cell types is unacceptably low.

136 igher threshold values (>20%) resulted in an unacceptably lower sensitivity for tumors.

137 Resolution was unacceptably poor if the samples dissolved in methanol w

138 initions for detecting RNFL thinning have an unacceptably poor level of specificity, and that more st

139 with each diagnosis whose prognosis remains unacceptably poor.

140 eated non-small-cell lung cancer (NSCLC) are unacceptably poor.

141 s associated with smoking, the habit remains unacceptably prevalent.

142 The useful lifetime was unacceptably short for the sensor that employed the bare

143 evaluate a single query at a time and can be unacceptably slow when the number of sequences in the qu

144 his approach is life sustaining, it is still unacceptably suboptimal with poor clinical outcomes of p

145 the disease or that the treatment will prove unacceptably toxic.