ライフサイエンスコーパス: uncoordinated

1 y die as embryos or larvae, and are severely uncoordinated.

2 NS feedback, contraction of body segments is uncoordinated.

3 ilia in Drosophila, leaving the fly deaf and uncoordinated.

4 d States have tended to be opportunistic and uncoordinated.

5 ns, where the mitochondrial movement becomes uncoordinated.

6 unction mutants are small, slow growing, and uncoordinated.

7 hat the novel Src homology (SH) 3/SH2 ligand-Uncoordinated 119 (Unc119) associates with CD3 and CD4,

8 >GTC; V22G) of the signaling adaptor protein Uncoordinated 119 (Unc119) in an ICL patient.

9 The transport depends on the adaptor protein Uncoordinated 119 (Unc119), on the GTPase rat brain 11 (

10 e strongly affected by the signaling protein uncoordinated 119 (Unc119).

11 A mammalian uncoordinated 119 protein (UNC119), also known as Retina

12 show a specific role for Rab34 and mammalian uncoordinated 13-2 (Munc13-2) in phagolysosome biogenesi

13 f four of the five proteins in the mammalian uncoordinated-13 (Munc13) family have been identified as

14 tor (SNARE) and Secretory 1 (Sec1)/mammalian uncoordinated-18 (Munc18)-like (SM) proteins, but it is

15 , a mechanism likely shared by the mammalian uncoordinated-18-1 protein (Munc18-1).

16 usly expressed Sec1/Munc18 protein mammalian uncoordinated-18c (Munc18c) regulates membrane fusion by

17 The repulsion-mediating netrin-1 uncoordinated-5 (UNC5) receptors are expressed by neuron

18 Neogenin, uncoordinated-5 (UNC5)A, and UNC5B were expressed at low

19 g netrin-1, deleted in colorectal cancer, or uncoordinated-5 homolog B (UNC5B) decreases YAP protein

20 receptors, deleted in colorectal cancer and uncoordinated-5 homolog, up-regulates YAP expression, es

21 f rapamycin signaling and phosphorylation of uncoordinated 51-like kinase (ULK) 1 in mtDNA-mutator mi

22 t promoted vascular permeability through the uncoordinated 5B (UNC5B) receptor.

23 f-function mutations of the RYR gene unc-68 (uncoordinated 68) essentially abolished large-amplitude

24 ough viable, d-plp mutant flies are severely uncoordinated, a phenotype usually associated with defec

25 nct from the resolution activity) are due to uncoordinated actions of the catalytic domains.

26 rons and resulted in more neurons exhibiting uncoordinated activity patterns at later time points.

27 nteric neurons usually displayed ongoing but uncoordinated activity.

28 of the dominant act-2 mutations resulted in uncoordinated adult movement.

29 ion of a thiourea-nitronate complex with the uncoordinated aldehyde.

30 the smallest change compared to that of the uncoordinated alkyne.

31 Animals mutant in this gene are severely uncoordinated and also exhibit defects in cell migration

32 aptojanin mutants in C. elegans are severely uncoordinated and are depleted of synaptic vesicles, pos

33 proceed through or to attempt to re-enter an uncoordinated and consequently fatal cell cycle.

34 Aggressive uncoordinated and coordinated approaches were highly sim

35 podermal P-cell nuclear migration results in uncoordinated and egg-laying-defective animals.

36 Too frequently, healthcare delivery is uncoordinated and has many providers who are not adequat

37 an attempt to re-enter the cell cycle in an uncoordinated and inappropriate manner.

38 ty for movement, although they are extremely uncoordinated and incapable of feeding.

39 subunit undergoes conformational transitions uncoordinated and independent of each other.

40 ble lev-8; acr-8-null mutant, which shows an uncoordinated and levamisole-resistant phenotype, reveal

41 cessive directional stepping, but it becomes uncoordinated and the stepping pattern shows a greater v

42 ion of cooperation assume that punishment is uncoordinated and unconditional.

43 and ventral nerve cord-resulting in sterile, uncoordinated animals-while others affect embryonic divi

44 vised in the light of new data demonstrating uncoordinated behavior among kinetochore-associated micr

45 significant impairment of motility including uncoordinated bends, severely reduced beat frequency, an

46 herein is a "through-arene" activation of an uncoordinated benzylic C-H bond that is 6 bonds away fro

47 dly induced several additional malformed and uncoordinated blood vessel structures that originated ou

48 o2 in proprioceptive neurons showed severely uncoordinated body movements and abnormal limb positions

49 formation gap that makes doctor shopping and uncoordinated care possible, states have created prescri

50 umbers of prescribers may signal dangerously uncoordinated care.

51 Loss-of-function mutants show irregular, uncoordinated cell divisions throughout embryogenesis, a

52 Thus, bacteria elongate by the uncoordinated, circumferential movements of synthetic co

53 21.3% more averted cases (n = 408) than did uncoordinated control at year 5.

54 s, facility-level infection control efforts (uncoordinated control measures), and a coordinated regio

55 y DOA4 is needed in S. cerevisiae to prevent uncoordinated DNA replication.

56 oteins is omitted from the dilution mixture, uncoordinated DNA synthesis occurs, and/or large Okazaki

57 ergone a formal [2+2] cycloaddition with the uncoordinated double bond of the 4,5-eta(2)-furan ligand

58 r a weak allele in vha-12 are viable but are uncoordinated due to decreased neurotransmission.

59 iscrete behavioral deficits, including slow, uncoordinated eclosion and an insensitivity to ecdysis-t

60 ubstrate, but how mitochondria contribute to uncoordinated electrical activity is poorly understood.

61 cytokine receptor family whose increased and uncoordinated expression may lead to myeloid leukemia by

62 ate the role of the mammalian Atg1 homologs, uncoordinated family member (unc)-51-like kinase 1 and 2

63 Caenorhabditis elegans CAPS ortholog UNC-31 (uncoordinated family member) and determined its role in

64 nt for Gbeta1, the pLLP cells migrated in an uncoordinated fashion and were unable to extend protrusi

65 ependymal cilia was disrupted, resulting in uncoordinated flow of CSF.

66 (mammalian homolog of Caenorhabditis elegans uncoordinated gene 13) proteins play essential roles in

67 alian homolog of the Caenorhabditis elegans "uncoordinated" gene (unc-13), as a candidate gene for cr

68 est correlation of the distances between the uncoordinated Gla oxygen atoms is with the intercalcium

69 present a simple delay of growth but instead uncoordinated growth plate development.

70 DFT calculations to hydrogen bonding between uncoordinated H2O and a peroxo ligand.

71 an OOH* intermediate on the high density of uncoordinated hollow-site C atoms with respect to the Co

72 unc-3 mutants are uncoordinated in locomotion.

73 these phenotypes suggest that development is uncoordinated in Rgd2-R(-) mutant leaves, so that leaf c

74 The gene unc-76 (unc, uncoordinated) is necessary for normal axonal bundling a

75 g gait, and the cord of DCC KO mice exhibits uncoordinated left and right oscillations.

76 ng pattern, and the DCC KO network exhibited uncoordinated left-right activity.

77 max, limb movement is impaired, ranging from uncoordinated leg swimming to complete quadriplegia.

78 3a gene results in defective suckling and in uncoordinated limb and trunk movements, leading to early

79 trast, young infants display exaggerated and uncoordinated limb reflexes [2].

80 u pan-neuronal expression caused progressive uncoordinated locomotion (Unc), characteristic of nervou

81 ventral cord motoneuron precursors result in uncoordinated locomotion of unc-85 mutant larvae by the

82 a novel class of loss-of-function alleles of uncoordinated locomotion(unc)-108, which encodes the Cae

83 as follows: volatile anesthetic sensitivity, uncoordinated locomotion, and a constitutive alternative

84 ious phenotypes (short life span, sterility, uncoordinated locomotion, and morphological defects).

85 ing of neuromuscular junctions, resulting in uncoordinated locomotion.

86 s, a disruption of any of these steps causes uncoordinated locomotory behavior (unc phenotype).

87 culate coordination's effects in relation to uncoordinated management and other reference scenarios.

88 to optimal coordinated management is optimal uncoordinated management, which can be identified at the

89 LacY, and the cavities open and close in an uncoordinated manner.

90 This does not agree with an uncoordinated mechanism where each subunit functions ind

91 observed, which are related to stochastic or uncoordinated molecular processes.

92 Both uncoordinated motility of syncytia and adhesion to CD4(+

93 ated tau accumulation, neurodegeneration and uncoordinated movement (Unc).

94 malities in body wall and sex muscles led to uncoordinated movement and egg-laying defects.

95 Two mutant alleles of the twk-18 gene confer uncoordinated movement and paralysis in C. elegans.

96 -2 result in severe body morphology defects, uncoordinated movement, adult sterility, abnormal moltin

97 rations, malformation of the posterior body, uncoordinated movement, and defective egg laying.

98 ere previously recognized as having slightly uncoordinated movement, are highly resistant to ethanol

99 nt with premature aging, including kyphosis, uncoordinated movement, hypogonadism, infertility, sever

100 asting, hypogonadism, osteopenia, emphysema, uncoordinated movement, T cell dysregulation, and atroph

101 regated tau leading to neurodegeneration and uncoordinated movement.

102 and biochemical analyses indicated that the uncoordinated movements of these mutant filaments were c

103 These phenotypes include uncoordinated movements, variable embryonic lethality, a

104 nctive dysfunction of the hind legs, causing uncoordinated movements.

105 A class of uncoordinated mutants called "fainters" partially suppre

106 e Ru(IV) horizontal lineO oxo species to the uncoordinated nitrogen of the NPM ligand.

107 The uncoordinated, nonaromatic double bond of this ligand un

108 , returning to the pre-managed care model of uncoordinated open access to specialists is a poor solut

109 with all Ty1-related genes shut off, without uncoordinated or mosaic expression in any individual cel

110 xylate and ketone oxygen; (ii) attack of the uncoordinated oxygen of the bound O(2) on the ketone car

111 By using the uncoordinated phenotype as a read-out of TDP-43 overexpr

112 otor velocity in vitro but produces a severe uncoordinated phenotype in transgenic C. elegans, sugges

113 we screened for mutations that suppress the uncoordinated phenotype of UNC-17(G347R) mutants.

114 l overexpression of TDP-1 also results in an uncoordinated phenotype, while genetic deletion of the t

115 Pag-3 mutants also show a reverse kinker uncoordinated phenotype.

116 n downstream of exon 15, which results in an uncoordinated phenotype.

117 of cho-1 mutants, giving rise to a synthetic uncoordinated phenotype.

118 ronal expression of human TDP-43 exhibit an 'uncoordinated' phenotype and have abnormal motorneuron s

119 The vast, uncoordinated proliferation of bioinformatics resources

120 h cooperation: cells mutate to phenotypes of uncoordinated proliferation.

121 econd His ligand recruited from a previously uncoordinated protein side chain.

122 During development, this seemingly uncoordinated reaction is a critical driver of cellular

123 pression experiments identified the receptor uncoordinated receptor-5 (UNC5A) as an antagonist of the

124 nonessential, and deleting this gene causes uncoordinated replication.

125 Mutations in the KLP64D gene cause uncoordinated sluggish movement and death, and reduce tr

126 partially via ligand release to re-form the uncoordinated species, in competition with binding of th

127 t prioritizes vaccination campaigns and uses uncoordinated staff incentives.

128 ned to optimize the effectiveness of random, uncoordinated stepping: (1) the formation of three-heade

129 including cleft palate, poor feeding with an uncoordinated suck, hypotonia and decreased movement.

130 The eight uncoordinated surface gold atoms in the Au22(L(8))6 nano

131 l risk of developing malnutrition because of uncoordinated swallowing, gastroesophageal reflux, and c

132 However, the uncoordinated switching of multiple motors interrupts an

133 ehavioral experiments in which punishment is uncoordinated, the sum of costs to punishers and their t

134 d thiolates, e.g., metallothionein (MT), and uncoordinated thiolates, e.g., glutathione, react with b

135 contractions are weaker, less frequent, and uncoordinated throughout the sequence of ovulation event

136 s in a hexameric ring of a mutant p97 become uncoordinated, thus impacting its ability to process sub

137 orylated in CD45 null NK cells, resulting in uncoordinated tyrosine-mediated signaling upon Ly-49D li

138 ated tau accumulation, neurodegeneration and uncoordinated (Unc) movement.

139 uncoordinated (unc) mutants of Drosophila, which lack tr

140 Nine uncoordinated (unc) mutations were used to block clumpin

141 of bar-1 from the 321-bp element rescued the Uncoordinated (Unc) phenotype of bar-1 mutants, but not

142 educed levels of CoQ result in a progressive uncoordinated (Unc) phenotype that is correlated with th

143 e to adulthood exhibit variably dumpy (Dpy), uncoordinated (Unc), and egg-laying defective (Egl) phen

144 In Caenorhabditis elegans, uncoordinated (unc)-55 encodes a nuclear hormone recepto

145 Coordinated Ca(2+) transients became uncoordinated using both these approaches, supporting th

146 Cerebellar damage results in uncoordinated, variable and dysmetric movements known as

147 interrupted cardiac morphogenesis following uncoordinated ventricular contraction.

148 ctility that appeared to be non-rhythmic and uncoordinated was observed in Ano1 KO jejunum.

149 lly reduced forward progressive velocity and uncoordinated waveform propagation along the flagellum.

150 ration within the GTPase domain that becomes uncoordinated when shifted to high temperature and that

151 thin the ICC-MY network in Ano1 KO mice were uncoordinated, while ICC-MY Ca(2+) transients in Ano1 WT

152 to address this issue have been isolated and uncoordinated, with little focus on sustainable and inte

153 ansduction, we discovered a line of deaf and uncoordinated zebrafish with defective hair-cell functio