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1 emonstrating that these two processes can be uncoupled.
2 static potential of these populations can be uncoupled.
3 chondrial content and functional scaling are uncoupled.
4 tance, confirming that the two traits can be uncoupled.
5 8hc, the two functions of the protein can be uncoupled.
6 adenine and guanine nucleotide metabolism is uncoupled.
7 or 1 (IPS-1, MAVS) and could be functionally uncoupled.
8 and morphological Fe deficiency responses is uncoupled.
9 ctive oxygen species (ROS) and are partially uncoupled.
10 l membrane potential following mitochondrial uncoupling.
11 ncoupling protein 3 (UCP3) and mitochondrial uncoupling.
12 of the carrier to adrenergic activation and uncoupling.
13 fatty acid and glucose oxidation, as well as uncoupling.
14 NAFLD is via salicylate-driven mitochondrial uncoupling.
15 educed antioxidant capacity of cells and NOS uncoupling.
16 blasts during pharmacological gap junctional uncoupling.
19 development of liver-targeted mitochondrial uncoupling agents as a potential novel therapy for lipod
20 ere of the Junggar Basin to the north became uncoupled along the Moho, and the mantle below the Moho
21 ellulose synthesis and cell expansion can be uncoupled and are regulated by different mechanisms.
25 o limit the reduction in stroke volume, with uncoupling and increased wall stress as a consequence.
26 s deregulation can explain the mitochondrial uncoupling and lower ATP levels in VCP mutation-bearing
29 upted feedback, apoptosis and divisions were uncoupled, and the organ developed either hyperplasia or
31 metabolic substrate usage and mitochondrial uncoupling, and protects against ischaemia/reperfusion.
34 ative stress and nitric oxide synthase (NOS) uncoupling are thought to contribute to Fabry cardiovasc
36 n being regulated, instead gradually becomes uncoupled as nucleosome sliding reaches an end point and
39 tion mutants from a constitutive promoter to uncouple Atf1 activity from endogenous, stress-activated
41 egulating B cell fate have been difficult to uncouple because a single enzyme, activation-induced cyt
42 tween alphaL alphaI and beta2 betaI could be uncoupled because the beta2 extension and headpiece open
43 e that ammonia- and nitrite-oxidation become uncoupled between 20 and 30 degrees C, leading to nitrit
45 ine-bound closed conformation, revealing the uncoupling between ATP-PRT open and closed conformations
48 an imbalance in glucose carbon allocation by uncoupling biosynthetic pathway activity, which could di
52 V or caCaMKIV, respectively, suggesting that uncoupling CaMKIV activation from activity generates an
55 terol induced MB as measured by increases in uncoupled cellular respiration and PGC-1alpha and NDUFS1
56 ded for the CPuORF action, since plants with uncoupled chloroplasts did not show uORF-dependent repre
59 ue for the circadian system, can selectively uncouple circadian rhythms in metabolic physiology from
61 t produces mild liver-targeted mitochondrial uncoupling could decrease hypertriglyceridemia and rever
62 are differentially regulated in response to uncoupling Crkl from its signaling pathways in the devel
64 at S384 by the PP2A-B56 phosphatase, thereby uncoupling cyclin E degradation from cyclin E-CDK2 activ
65 n of the model under altered situations with uncoupled differentiation and proliferation was demonstr
67 le entry and progression through mitosis and uncoupled duration of mitosis from variability in cell c
68 Whereas mutant coupling junction residues uncoupled during activation and caused gain of function,
72 oA oxidation and its concentration-dependent uncoupling effect, together with a partial lipid-depende
74 e fuel role of lipids is influenced by their uncoupling effects, and how this affects mitochondrial e
78 we identified, for the first time, that OSS uncouples eNOS, which was corrected by RNAi of NOXO1.
81 adation, but increases chromosomal breakage, uncoupling fork protection, and chromosome stability.
82 he terminal alpha-helix to thermodynamically uncouple from the rest of the protein and preferentially
83 However, bivalent biorientation remained uncoupled from APC activity, leading to error-prone chro
84 demonstrates that chromosome condensation is uncoupled from cell cycle progression when MCPH1 functio
88 B receptors are selectively upregulated, but uncoupled from downstream extracellular signal-regulated
90 insulin secretion becomes dysregulated (ie, uncoupled from glucose metabolism) so that insulin secre
92 a benthamiana The transgene-derived satBaMV, uncoupled from HV replication, was able to move autonomo
97 hich is regulated by amino acid amounts, was uncoupled from limiting amino acids in the G1 phase of t
98 ly induction of distal pre-metastatic niches uncoupled from lymphangiogenesis at primary lesions.
99 teps of unsaturated LCFA degradation proceed uncoupled from methanogenesis, accumulation of saturated
100 ences in the magnitude of scaling among taxa uncoupled from observed differences in the temporal stru
101 species' longevity across the three clades, uncoupled from other parameters, such as basal metabolic
102 ancer cell death triggered by statins can be uncoupled from prenylation of the RAS superfamily of onc
106 Metabolic adaptations in early pregnancy are uncoupled from the circadian clock, whereas in late preg
107 ence that lytic cycle gene expression can be uncoupled from the full reactivation program, arguing fo
110 IVR whereby the mechanism of drug release is uncoupled from the interaction of the drug with the ring
112 elivery of an engineered DNA-binding protein uncoupled from the repressor domain can produce efficien
113 s that the process of data mining can become uncoupled from the scientific process of clinical interp
114 onal regulation of the B-CAP-G pseudogene is uncoupled from the standard regulation of the genes that
115 red whether hypoglycemia in SCHAD CHI can be uncoupled from the systemic effect on fatty acid oxidati
116 tor binding to UASs is widespread, partially uncoupled from transcription, and mediated in part by TF
119 yofilament Ca(2+) sensitivity and, moreover, uncoupling from the impact of phosphorylation of cTnI me
120 onflicting phenotypes suggest the cell cycle uncouples GA and ABA responses in germinating Arabidopsi
123 all cells in the entire electro-mechanically uncoupled heart during the looping stage of live embryon
125 deoffs mediated by the hormone jasmonate are uncoupled in an Arabidopsis mutant (jazQ phyB) lacking a
127 the leading-head lever arm of a MVI dimer is uncoupled, in accord with the inference drawn from polar
128 h processes involved in cell turnover become uncoupled, including pharmacological treatments and dise
131 ing the remodelling and turnover of K16, and uncoupling it from K6, iRHOM2 regulates the epithelial r
132 -p38 MAPK-CMA pathway in the mouse brain and uncoupling it results in a greater loss of SNc dopaminer
135 ession from an estrogen-independent promoter uncoupled LRIG1 from estrogen regulation, thus sustainin
136 adipogenic, insulin sensitivity, and energy uncoupling machinery, while limiting inflammation in WAT
138 Furthermore, we find that 3D ECM engagement uncouples MCAK-mediated regulation of MT growth persiste
139 hetic anion transporters and potentially the uncoupling mechanism of naturally occurring membrane pro
141 DELLA gain-of-function mutant Sln1d (4) also uncoupled meristem and inflorescence size from plant hei
142 . demonstrate how heat shock factor 1 (HSF1) uncouples metabolic control from proteostatic regulation
144 kinase 1 (PINK1) and PARK2 translocation to uncoupled mitochondria, all of which were recovered by M
145 Blocking ROS production with rotenone by uncoupling mitochondria or by expressing the alternative
149 ates vibrational polaritons shifted from the uncoupled molecular resonances and provides a convenient
151 wever, regulated their mRNA concentration by uncoupling mRNA stability from the transcription rate.
155 uggesting that impaired retrograde transport uncouples nascent IMVs from the IEV membranes at the sit
156 hat post-translational modifications of Numb uncouple Numb from p53 and lead to p53 destabilization.
157 hondrial matrix independent of ATP synthase, uncoupling nutrient metabolism from ATP generation.
158 ocyte fatty acid-binding protein (FABP4/aP2) uncouples obesity from inflammation via upregulation of
159 therapeutic efficacy through pharmacological uncoupling of a convergence point of NF-kappaB-mediated
160 halamic inflammatory pathways results in the uncoupling of caloric intake and energy expenditure, fos
163 has no effect on work output, indicating an uncoupling of disassembly speed from protofilament strai
166 HFS throughout the light-dark cycle suggests uncoupling of hypothalamic responses involving appetite-
168 act epithelia; the other prerequisite is the uncoupling of intercellular contacts, which induces Rho-
169 dent impaired autophagic flux after chemical uncoupling of mitochondria, increased mitochondrial-prot
172 Inadequate availability of BH4 leads to uncoupling of nitric oxide synthases and production of h
173 a highly phase-specific pattern, suggesting uncoupling of phenotypic evolution across life-history p
174 ate testable predictions for coupling versus uncoupling of phenotypic evolution of tadpole and adult
179 tion of GC responses was, in part, caused by uncoupling of Tfh-B cell interactions, as evidenced by r
182 n, pharmacologically induced neuromechanical uncoupling of the diaphragm should facilitate lung-prote
183 hat has little constitutive activity reveals uncoupling of the ligand-binding domain from conserved c
184 ia TSC1 gene deletion in chondrocytes causes uncoupling of the normal proliferation and differentiati
185 in avian DT40 cells, indicative of extensive uncoupling of the replicative helicase and polymerase.
186 ural features within the S4-S5 linker permit uncoupling of the voltage sensor from the pore in the ab
190 ges for coherent population transfer between uncoupled or weakly coupled states and has the potential
191 propose that spatial control of ciliogenesis uncouples or specifies sensory properties of cilia.
193 e and inhibited by IL-4R-signaling in vitro, uncoupling parasite killing from expulsion mechanisms.
194 PR)50 was modified by genetic mutations that uncouple physiological aging from chronological aging.
196 equire an assessment of membrane affinity to uncouple protein binding from membrane interactions.
198 expression of the brown fat signature genes uncoupling protein (UCP)-1 and peroxisome proliferator-a
201 wn AT showed reduced activity with decreased uncoupling protein 1 (ucp-1), cell death-inducing DFFA-l
202 dipocytes are specialized cells that express uncoupling protein 1 (UCP1) and dissipate chemical energ
203 m promoters of BAT-specific genes, including uncoupling protein 1 (Ucp1) and peroxisome proliferator-
205 h was accompanied by increased expression of uncoupling protein 1 (UCP1) and UCP3 in brown adipose ti
207 is is primarily accomplished by induction of uncoupling protein 1 (UCP1) in brown and beige adipocyte
212 al analysis revealed extensive expression of uncoupling protein 1 (UCP1), a definitive marker of brow
213 t of glucose homeostasis were independent of uncoupling protein 1 (UCP1), but required expression of
214 protein restriction increases adipose tissue uncoupling protein 1 (UCP1), energy expenditure and food
215 uce expression of thermogenic genes, such as uncoupling protein 1 (Ucp1), in adipocytes cultured with
221 loss was significantly associated with less uncoupling protein 1 expression (P = 0.006, R(2) = 0.09)
225 neither presence nor thermogenic function of uncoupling protein 1(+) beige adipocytes contributed to
226 ramembraneous segments and the mitochondrial uncoupling protein 1, which is a transmembrane protein e
227 d body weight gain, induced the formation of uncoupling protein 1-positive beige adipocytes in white
229 Additionally, intracellular glutathione and uncoupling protein 2 (UCP2) gene expressions were quanti
234 ion, fatty acid oxidation, and mitochondrial uncoupling protein 3 (UCP3) levels, while increasing gly
236 the well-known betaAR-dependent increase of uncoupling protein UCP1 expression and expansion of beig
238 issipates nutritional energy as heat via the uncoupling protein-1 (UCP1) and BAT activity correlates
240 our group showed an increased expression of uncoupling protein-2 (UCP2) in pancreas from rats with B
241 This gene expression pattern agrees with uncoupled rates of trait evolution among life-history ph
242 ves SAM to form 5'-deoxyadenosine in a slow, uncoupled reaction characteristic of radical SAM enzymes
243 neuronal stimuli, resulting in neurovascular uncoupling, reduced oxygen supply to the brain and metab
244 controls to evaluate: (i) ADMA-mediated NOS uncoupling reduces epithelial production of NO and incre
245 ed to play a role in apoptotic cell death by uncoupling regions important for IP3 binding from the ch
246 tion; menthol was less capable of augmenting uncoupled respiration (thermogenesis) in brown adipocyte
247 BAT) dissipates energy through Ucp1-mediated uncoupled respiration and its activation may represent a
248 ed in the priming of mitochondria to perform uncoupled respiration downstream of adenylate cyclase.
250 up-regulated UCP-1 expression and augmented uncoupled respiration predominantly in white adipocytes
251 es convert chemical energy into heat through uncoupled respiration to defend against cold stress.
252 adipocytes exhibited defective induction of uncoupled respiration whereas their glycolytic flux and
253 d disruption of Ant2 in mouse liver enhances uncoupled respiration without damaging mitochondrial int
259 ownregulated UCP-1 expression, and mitigated uncoupled respiration; menthol was less capable of augme
262 ssary for the initiation of sexual behavior, uncoupling sexual behavior from reproductive status.
264 es targeting those sequences, we genetically uncoupled Smy1's functions in regulating formins and myo
267 e); end-systolic peak (peak ); and diastolic uncoupling (systolic -diastolic at same volume) during e
268 site bias Get3 toward closed conformations, uncouple TA binding from induced Get3*Get4/5 disassembly
269 heterodimer, with beta2AR activation rapidly uncoupling TAS2R14 function ( approximately 65% desensit
271 mologs and inactive AvrRpt2 variants, we can uncouple the inhibition of MPK4/MPK11 activation from th
272 al introduction of a FVIIa-M306D mutation to uncouple the sTF-mediated allosteric stimulation of FVII
276 lows us to formulate a stochastic model that uncouples the effects of productivity, individual abilit
278 ow that the two-step lipid-binding mechanism uncouples the membrane association of FtsY from its conf
279 cell antigen receptor ubiquitination in vivo uncouples the receptor from CD19 phosphorylation and pho
280 e without affecting stress behavior, thereby uncoupling the contribution of a specific OXT cluster to
281 the perceived intention of others which, by uncoupling the dynamics of sensorimotor facilitation, co
282 t binds directly to the dynein motor domain, uncoupling the enzymatic and mechanical cycles of the mo
283 and androgen receptor signaling, effectively uncoupling the normal negative feedback between these tw
285 anosensing and determines if cells couple or uncouple their proliferative and motility responses to E
286 Ss) and nodes of Ranvier, it is difficult to uncouple their roles in maintaining axon integrity from
287 ng the host and the pathogen separately, may uncouple their spatial distribution to create a mismatch
288 godendrocyte differentiation and maturation, uncoupling them at a transcriptional level and highlight
289 to whether factors or mechanisms exist that uncouple these processes and extend healthspan and reduc
290 m fibrils, thus providing powerful tools for uncoupling these processes and investigating the role of
292 The present work offers two strategies for uncoupling these two processes and converting concerted
296 rmation of triplet-triplet multiexcitons and uncoupled triplet excitons through singlet fission.
297 esses the underlying basis for mitochondrial uncoupling using VCP knockdown neuroblastoma cell lines,
298 electric dipoles and magnetic dipoles become uncoupled when electrons can circulate around a ring wit
299 balance leads to nitric oxide synthase (NOS) uncoupling with reduced nitric oxide (NO) formation and
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