ライフサイエンスコーパス: uncover @3 mechanism

1 nsition (MIT) offers unique opportunities to uncover their driving mechanism.

2 ng campomelic dysplasia and will likely help uncover other disease mechanisms.

3 study of cell-to-cell variability could help uncover novel cellular regulation mechanisms.

4 ence of stroke on alcohol consumption and to uncover the underlying nigrostriatal mechanism.

5 of the 759G>T (p.L254F) mutation in OGT that uncovered a compensation mechanism, albeit imperfect, gi

6 between G2019S-LRRK2 and alpha-synuclein may uncover new mechanisms and targets for neuroprotection.

7 the organisms that are buried there, both to uncover new mechanisms and to marvel at the richness of

8 d we describe the animal models available to uncover pathogenic mechanisms and related host immune re

9 Each new description of TEI helps uncover the properties, molecular mechanisms and biologi

10 nt frontotemporal dementia (bvFTD) will help uncover underlying biological mechanisms and improve cli

11 Our study has uncovered the mechanism and structural elements of conva

12 interest to binaural-hearing researchers for uncovering brain mechanisms and for improving signal-pro

13 ytes (hiPSC-CMs) are a powerful platform for uncovering disease mechanisms and assessing drugs for ef

14 challenges of a genomics-driven approach to uncovering neuropsychiatric disease mechanisms and facil

15 nflammasome activation in trophoblast cells, uncovering a novel thromboinflammatory mechanism at the

16 n pumping behavior in urease-based pumps and uncover the mechanisms behind these dynamics.

17 Taken together, these data uncover a co-degradation mechanism between PIFs and HFR1

18 Here we uncover a dual molecular mechanism by which the CHK2-BRC

19 ilar role of ACS-4 in a male/female species, uncover a likely conserved mechanism by which FA, an env

20 onse of the cleavage-stage embryo to CIN and uncover a mechanism by which centromeric fission induces

21 Together, these results uncover a mechanism by which competitive recruitment of

22 These data uncover a mechanism by which IFN is likely elicited duri

23 Our data uncover a mechanism by which polarity information can be

24 These results uncover a mechanism by which SVNI exploits a host antivi

25 These results uncover a mechanism by which SVNI exploits a host antivi

26 erythrocyte removal and iron recycling, and uncover a mechanism by which the body adapts to fluctuat

27 Collectively, our data uncover a neural mechanism by which olivocerebellar dysf

28 Our findings uncover a new mechanism by which PSaV manipulates the ho

29 Our findings uncover a novel mechanism by which AUF1 binding and tran

30 Our findings uncover a novel mechanism by which cell-ECM interactions

31 del of transitional epithelial carcinoma and uncover a novel mechanism by which loss of TGFbeta recep

32 Our results uncover a novel mechanism by which MALAT1 regulates the

33 Thus, these findings uncover a novel mechanism by which PML loss may contribu

34 Here, we uncover a regulatory mechanism by which glucose recruits

35 14Ac and H3K23Ac in response to ethylene and uncover a unique mechanism by which ENAP1 interacts with

36 These findings uncover an unexpected mechanism by which sustained infla

37 These findings place p57Kip2 in DDR and uncover molecular mechanisms by which p57Kip2 suppresses

38 These findings uncover new mechanisms by which AMPK could potentially m

39 directing clamp loaders to 3'DNA, as well as uncover nuances in the mechanisms by which SSBs perform

40 etic-induced obese mouse models were used to uncover potential mechanisms by which obesity increases

41 Collectively, these findings uncover the epigenetic mechanism by which PRC2 controls

42 In efforts to uncover the mechanism by which SLFN5 promotes GBM tumori

43 mework to study other ecosystem services, to uncover the mechanisms by which ecosystem protection ben

44 Gene expression profiling can be used to uncover the mechanisms by which loci identified through

45 To uncover the mechanisms by which multicellular tissues al

46 To uncover the regulatory mechanisms by which common insert

47 Together, these data uncover two distinct mechanisms by which mutp53 enhances

48 In conclusion, we have uncovered a mechanism by which chronic, but not acute, L

49 Here, we uncovered a novel mechanism by which catecholamines indu

50 Moreover, we uncovered a novel mechanism by which IL-37 suppressed tu

51 These findings for the first time uncovered a novel mechanism by which SRW pollen initiate

52 cgammaR function in human monocytes and have uncovered another mechanism by which TLR8 agonists may e

53 Our systematic approach uncovered key mechanisms by which EBV oncoproteins activ

54 inase 1 or TNK2) as an oncogenic kinase, has uncovered novel mechanisms by which tyrosine kinase sign

55 Here, we uncovered the molecular mechanism by which this phosphor

56 These findings uncovered the molecular mechanisms by which p38alpha MAP

57 Uncovering the mechanisms by which organotypic endotheli

58 Uncovering the mechanisms by which single-stranded bindi

59 This work uncovers a mechanism by which a single GPCR mediates pse

60 roliferation of thyroid follicular cells and uncovers a mechanism by which GLIS3 deficiency causes ne

61 This study uncovers a mechanism by which Hof1 controls timely activ

62 ts virus particle production and release and uncovers a new mechanism by which Ebola virus infectivit

63 The current work uncovers a new mechanism by which nanoART can enhance vi

64 This new Drosophila model uncovers a novel mechanism by which upregulated expressi

65 Our study uncovers a previously unknown mechanism by which GOT2 ac

66 Our study uncovers a previously unrecognized mechanism by which be

67 Thus, our work uncovers an important mechanism by which C. elegans incr

68 This study uncovers the metabolic mechanisms by which IL-7 tailors

69 Our study uncovers two distinct mechanisms by which motivation imp

70 Our findings uncovering a SUMOylation-based mechanism controlling WAS

71 Our study thus uncovers a novel regulatory mechanism controlling the re

72 Our results uncover a molecular mechanism coordinating critical feat

73 To uncover the precise mechanisms coordinating proliferatio

74 ilitation and discuss how recent progress in uncovering the underlying molecular mechanisms could ena

75 5 in MHCI transcription in activated DCs, we uncover a general mechanism counteracting low MHCI surfa

76 Our findings uncover an important mechanism defining how ubiquitin at

77 preferences and, especially, traits to help uncover the mechanisms driving plant community assembly.

78 innate immunity from the past 2 decades has uncovered many novel mechanisms elucidating how immune c

79 Our results here uncover the molecular mechanisms employed by YAP to exer

80 Our results uncover a mechanism for circular RNA biogenesis that may

81 tastasis, delineate downstream pathways, and uncover a mechanism for different potassium channels to

82 bitory interneurons, and sensory neurons, we uncover a mechanism for generating alternative startle b

83 the model nematode Caenorhabditis elegans to uncover a mechanism for sensing humidity.

84 s pancreatic and colon cancers, our findings uncover a mechanism for TAM-mediated spheroid formation

85 e functionally distinct chromatin states and uncover a mechanism for the formation of transcriptional

86 Together, our findings uncover a new mechanism for liver metastasis formation i

87 These results uncover a new mechanism for Rac1 activation in tumors an

88 These results uncover a novel mechanism for a bHLH transcription facto

89 These results uncover a novel mechanism for E2F1 transcriptional activ

90 Our findings uncover a novel regulatory mechanism for methionine meta

91 We uncover a retrograde extension mechanism for axon growth

92 udy, we utilized a rare protective allele to uncover a TRIM62-mediated mechanism for regulation of CA

93 We uncover an alternative mechanism for anomalous Hall effe

94 Our results uncover an lncRNA-mediated mechanism for HIF-1 activatio

95 elegans feeding and used light as a tool to uncover molecular and neural mechanisms for gustation.

96 lternative splicing in the human thymus, and uncover novel mechanisms for CELF2 regulation that may b

97 To uncover the mechanism for Galphai regulation of adhesion

98 sing QM(DFT)/MM metadynamics simulations, we uncover the mechanism for reduction of the HRP Compound

99 Thus, our results have uncovered a fundamental regulatory mechanism for the act

100 We have uncovered a mechanism for effective viral transcription

101 Hence, we have uncovered a mechanism for how BR signaling can modulate

102 We have uncovered a noncanonical mechanism for sweet taste perce

103 Taken together, we have uncovered a novel mechanism for Smo activation by sumoyl

104 We recently uncovered a phosphatase-independent mechanism for dampen

105 Recent work has uncovered the mechanism for length control of this self-

106 subserve communications both to and from PFC-uncovering parallel oscillatory mechanisms for working m

107 Our study uncovers a novel molecular mechanism for regulating PD-L

108 troscopy and molecular dynamics simulations, uncovers a novel regulatory mechanism for ligand-induced

109 Thus, our study uncovers a novel regulatory mechanism for the developmen

110 Our study uncovers a previously unknown mechanism for the insulin

111 breast milk iron in neonatal development and uncovers an unexpected molecular mechanism for the regul

112 Overall, our results uncover novel phosphodependent mechanisms governing tau'

113 Study of laboratory model species has uncovered several possible canalization mechanisms, howe

114 te patient selection for Wee1 inhibition and uncover potential resistance mechanisms, identification

115 Our data uncover a mechanism in the control of Th17 cells that mi

116 These results uncover a novel mechanism in melanoma pathogenesis, wher

117 In this issue, Gu et al. uncover a novel mechanism in which immune signaling and

118 Aiming to uncover interdomain regulatory mechanisms in SHIP2, we d

119 Our findings uncover novel mechanisms in response to morphine-associa

120 Here, we uncover posttranslational regulatory mechanisms in the p

121 To uncover regulatory mechanisms in Hedgehog (Hh) signaling

122 Our findings uncovered a novel mechanism in which INT-767 activation

123 Here we uncovered a thalamocortical mechanism in which cortical

124 Unbiased genetic studies have uncovered surprising molecular mechanisms in human cellu

125 ed this effect to RET and NTRK1 blockade and uncovered the other additional mechanisms in gene fusion

126 In sum, our study uncovers a previously unknown mechanism in which RBF and

127 Our work uncovers diverse ubiquitin recognition mechanisms in the

128 These data uncover a novel molecular mechanism indicating that HDAC

129 trates how the study of diverse bacteria may uncover novel mechanisms involved in regulating bacteria

130 the lysosomal alterations in GD neurons and uncover the mechanisms involved, we used induced pluripo

131 Uncovering these mechanisms is important for our underst

132 Despite previous studies that attempted to uncover the mechanism leading to abnormal tooth developm

133 Here, we uncover a novel mechanism licensing transcription in hum

134 Our data uncover novel mechanisms linking MITF-dependent inhibiti

135 We have uncovered a conserved, robust mechanism linking mitochon

136 d genome-wide ribosome footprinting, we have uncovered a molecular mechanism linking this hormone's p

137 ned biochemical and cell-based approaches to uncover a dual pathogenic mechanism mediated by tau acet

138 Collectively, our study uncovers a novel regulatory mechanism mediating both iro

139 or localization of HDAC3 at myofilaments and uncover a novel mechanism modulating the motor activity

140 We have uncovered novel mechanisms modulating LTCC trafficking a

141 Striving to explain this discrepancy, we uncover a functional mechanism of A-to-I editing in regu

142 Wevers et al. (2014) uncover a mechanism of PRR antagonism where fungal-induc

143 Overall, our findings uncover a mechanism of SAC inactivation required for tim

144 These data uncover a new mechanism of apoptotic body formation in m

145 s issue of Molecular Cell, Heo et al. (2015) uncover a new mechanism of signal amplification during m

146 These results uncover a new molecular mechanism of tissue fibrogenesis

147 .1 gene transcription and, more importantly, uncover a novel mechanism of TFIID recruitment and gene

148 Together, we uncover a potential mechanism of how PTEN safeguards NSC

149 Together, our data uncover a previously unsuspected mechanism of how hyalur

150 ecent issue of Nature, Herault et al. (2017) uncover a unique spatiotemporal mechanism of granulocyte

151 Our data uncover an entirely novel mechanism of neuroprotection t

152 These studies uncover an RNA-mediated mechanism of targeting AID to DN

153 These findings uncover an unexpected mechanism of glucose sensing in sk

154 nd RANK signaling in osteoclastogenesis, and uncover an unrecognized pathophysiological mechanism of

155 , pharmacology, and genetic perturbations to uncover circuit and molecular mechanisms of DTQ and SIQ.

156 ughput screens at microscopic resolution can uncover molecular mechanisms of cellular dynamics, but r

157 ncreasingly employed in genomics research to uncover molecular mechanisms of disease and to explore p

158 These data uncover new mechanisms of retinal progenitor cell (RPC)-

159 as9 is a powerful gene editing tool that can uncover novel mechanisms of clustered miRNA regulation a

160 To uncover novel mechanisms of resistance to anti-HER2 ther

161 wed by behavioral studies (n = 6-8/group) to uncover novel molecular mechanisms of the positive reinf

162 g to model the effects of rare variation may uncover pathophysiological mechanisms of relevance to th

163 unit, confirm experimental observations, and uncover PI3Kalpha's mechanism of activation.

164 To uncover potential underlying mechanisms of this differen

165 To uncover the genetic mechanism of Xieyou9308's high yield

166 To uncover the mechanism of action of ZnO NPs on CT activit

167 Our results uncover the mechanism of activation of the canonical Wnt

168 Taken together, our results uncover the mechanism of how the FANCD2-FANCI complex ac

169 a unique mouse system for future studies to uncover the mechanism of transvection in mammals.

170 contributing to lifespan variation, and help uncover the mechanisms of aging.

171 sed cells will offer unique opportunities to uncover the molecular mechanism of a multitude of physio

172 ofiles on a variety of cancer cell types, to uncover the molecular mechanism of cancerogenesis.

173 ynamics and quantum chemical calculations to uncover the molecular mechanism of O2 diffusion within t

174 Here, we uncover the molecular mechanism of primed conversion by

175 These results uncover the principles and mechanisms of neuronal MT org

176 or colliculus (SC) have made it difficult to uncover their precise mechanisms of action.

177 We uncover two inter-organ mechanisms of protective immunit

178 In summary, this study has uncovered a long-sought mechanism of HCV cell-culture ad

179 In addition, these studies have uncovered a mechanism of innate allorecognition based on

180 Thus, our study not only uncovered a new mechanism of BES1 degradation but also p

181 Here, we uncovered an unexpected mechanism of RTK trafficking in

182 We have uncovered an unprecedented mechanism of viral replicatio

183 ryocytes and platelets have played a role in uncovering novel molecular mechanisms of megakaryopoiesi

184 ted modulation of the NE and EBV maturation, uncovering novel regulatory mechanisms of nuclear egress

185 ficult to analyze interface are paramount to uncovering the mechanism of their association.

186 By uncovering the molecular mechanisms of nucleic-acid bind

187 onsiderable efforts have been devoted toward uncovering the regulatory mechanisms of hematopoietic st

188 t on various aspects of sugar-derived LMWGs, uncovering their mechanisms of gelation, structural anal

189 Our study uncovers a critical mechanism of immunosuppression assoc

190 Taken together, our study uncovers a mechanism of azole resistance in C. albicans,

191 ponsible for miRNA 3' truncation in vivo and uncovers a mechanism of specificity determination in miR

192 ein affects protein-RNA interaction and also uncovers a mechanism of transcriptional regulation of th

193 Our study uncovers a new mechanism of action for DISC1 based on it

194 tor of NF-kappaB signaling pathway, but also uncovers a new mechanism of crosstalk between NF-kappaB

195 Our study uncovers a novel mechanism of somatic cell differentiati

196 Together, this study uncovers a unique molecular mechanism of lymphangiogenes

197 Our work uncovers an unexpected mechanism of protein synthesis, i

198 This discovery uncovers novel mechanisms of tumor-suppressor gene inact

199 Altogether, these results uncover an intricate mechanism orchestrated by the TIP60

200 or polygenic disorders have the potential to uncover novel molecular mechanisms participating in path

201 Our data thus uncover an important mechanism preventing spontaneous ag

202 ells are strongly stimulus dependent, and we uncover the circuit mechanisms producing this stimulus d

203 ells to stimulate insulin secretion in vitro Uncovering physiologic mechanisms promoting beta-cell su

204 Our data uncover a novel signaling mechanism regulating TRPM3 cha

205 e planarian epidermis as a novel paradigm to uncover the molecular mechanisms regulating ASC specific

206 xcessive or inappropriate immune activation, uncovering the mechanisms regulating Foxp3 level is requ

207 ation analysis provides a reliable method to uncover novel genes and mechanisms related to phenotypes

208 To uncover the mechanisms relevant to deregulated cell divi

209 Thus, we have uncovered an inhibitory mechanism required for adaptatio

210 Collectively, our work uncovered a new mechanism responsible for host defense a

211 of the JCI, Inoue, Abe, and colleagues have uncovered a targetable neuroimmunomodulatory mechanism t

212 Taken together, we have uncovered an important posttranscriptional mechanism tha

213 The findings uncover a biological mechanism that supports a 'slippery

214 These results uncover a central molecular mechanism that governs glyco

215 These findings uncover a mechanism that controls the activation of ER b

216 Collectively, these findings uncover a new underlying mechanism that models the progr

217 These results uncover a novel mechanism that implicates Aurora A in th

218 Taken together, our findings uncover a novel mechanism that M. catarrhalis uses to ev

219 Together, our data uncover a previously unidentified mechanism that links A

220 These findings uncover a protective mechanism that mediates cardiomyocy

221 t families of substrate saturation curves to uncover a simple kinetic mechanism that explains the app

222 These studies uncover a speed control mechanism that might allow selec

223 To uncover components of the mechanism that adjusts the rat

224 We find that the method can efficiently uncover detailed switching mechanisms that involve fluct

225 Furthermore, we uncover ionic and cellular mechanisms that suggest uniqu

226 studies interrogating this unique model may uncover metabolic regulatory mechanisms that are indepen

227 m phylogenetically well-defined lineages can uncover molecular mechanisms that underlie significant e

228 luences the effects of genetic variation and uncover multiple mechanisms that regulate and buffer exp

229 ference in IL-18 and IL-1beta regulation and uncover novel mechanisms that are relevant to the inflam

230 To uncover the mechanism that regulates insect pheromone se

231 fitting a mathematical model to the data, we uncover the mechanisms that mediate the stabilization of

232 Taken together, our study uncovered a mechanism that EV71 utilizes to promote host

233 copy in Drosophila melanogaster S2 cells, we uncovered a microtubule-independent mechanism that under

234 nscription factors control transcription, we uncovered a molecular mechanism that increases productiv

235 euromuscular junction as a model synapse, we uncovered a novel mechanism that regulates the distribut

236 Together, our findings have uncovered a previously unidentified mechanism that BCL11

237 Furthermore, we uncovered an integrated mechanism that acts at the trans

238 Taken together, our results have uncovered an lncRNA-based mechanism that modulates TGF-b

239 Our studies have therefore uncovered the regulatory mechanisms that underlie early

240 We uncovered two fibrillization mechanisms that govern the

241 of the chromosomal passenger complex (CPC), uncovering a feedback mechanism that couples furrowing w

242 Uncovering new mechanisms that control stromal cell beha

243 Uncovering the mechanisms that affect the binding specif

244 uctural properties of biological systems and uncovering the mechanisms that drive these systems.

245 Accordingly, there is great interest in uncovering the mechanisms that modulate the formation an

246 Our study uncovers a mechanism that links the remodeling of mitoch

247 romote efficient early junction assembly and uncover a new molecular mechanism through which PLEKHA7

248 Together, these data uncover a novel mechanism through which endodermal-myoca

249 These findings uncover a novel mechanism through which Shp2 regulates o

250 Our studies uncover a novel mechanism through which the dioxin-AHR a

251 nter response to a cholesterol-rich diet and uncover a PDL1-dependent mechanism through which MZB cel

252 In this issue, Singhvi et al. uncover cellular and molecular mechanisms through which

253 events can provide valuable opportunities to uncover the mechanisms through which the weather influen

254 ing a variety of complex network models, and uncover the underlying dynamical mechanism through an ei

255 Our study uncovers a noncanonical thermogenic mechanism through wh

256 of multiple active ligand-bound states, and uncovers a novel molecular mechanism through which FGFR-

257 l role of amylin deposition in the pancreas, uncover a novel contributing mechanism to cardiac myocyt

258 Collectively, our findings uncover a novel mechanism to control tumor-cell dissemin

259 Here we uncover a novel mechanism to escape the constraints of d

260 Together, these findings uncover an Ezh2-dependent mechanism to restrict the smoo

261 To uncover the underlying mechanism to these observations,

262 omal component specific for mRNP trafficking uncovering a new mechanism to couple mRNPs to endosomes.

263 ent structure is provided, which is a key to uncovering mutational and pathogenic mechanisms underlyi

264 ain architecture can control VGIC responses, uncover a mechanism underlying the diverse BacNa(V) volt

265 Together, these findings uncover a mechanism underlying the enigmatic association

266 an exciting model of tendon regeneration and uncover a novel cellular mechanism underlying regenerati

267 Together, our data uncover a previously unsuspected mechanism underlying de

268 5 in the regulation of synaptic function and uncover an intriguing microcircuit mechanism underlying

269 These findings uncover an unidentified mechanism underlying the precise

270 Research has begun to uncover common mechanisms underlying transmission of amy

271 pha in myeloid cells in CNS autoimmunity and uncover important molecular mechanisms underlying sex di

272 These findings may help uncover low-level perceptual mechanisms underlying delus

273 These results uncover molecular and biophysical mechanisms underlying

274 control in insect acoustic communication and uncover novel computations and mechanisms underlying the

275 Finally, we show that DISCERN can uncover potential mechanisms underlying network perturba

276 Our findings uncover some of the mechanisms underlying the pathologic

277 thways and genes involved in aging, and help uncover the genetic mechanisms underlying risk for age-r

278 Further work is required to replicate and uncover the mechanisms underlying the direct and interge

279 Here, we uncover the mechanisms underlying this paracrine tumouri

280 ctivity probes and optogenetic approaches to uncover the molecular mechanisms underlying cell invasio

281 elements of the immune system can help us to uncover the pathogenic mechanisms underlying CRS.

282 eptors in vivoSIGNIFICANCE STATEMENT We have uncovered a mechanism underlying olfactory receptor sens

283 CIs can enhance anti-tumor immune responses, uncovering a novel mechanism underlying the anti-tumor e

284 derscores the relevance of this sequence and uncovers a novel pathophysiological mechanism underlying

285 Altogether, our work uncovers the molecular mechanism underlying Prdm14-media

286 are rapidly enabling researchers to finally uncover the molecular mechanisms underpinning the astoni

287 arious syndromic or nonsyndromic diseases to uncover the molecular mechanisms underpinning these dise

288 Thus, we have uncovered a previously unidentified mechanism used by in

289 Our findings uncover (i) a mechanism utilized by KSHV to maintain lat

290 Here, we uncovered this mechanism via complete theoretical calcul

291 To uncover these mechanisms, we generated Mtdh knock-out mi

292 To uncover underlying pathogenic mechanisms, we found that

293 Here, we uncover a new mechanism where the transcription factor G

294 Molecular and genetic analysis uncovered a two-step mechanism, where release of CCL2 fr

295 prin-1 in myogenesis and muscle disease, and uncover a novel mechanism whereby disruption of the LINC

296 Mutations lacking nuclear localization uncover a novel mechanism whereby lipid phosphatase acti

297 lung chemokine expression in vivo These data uncover a novel mechanism whereby loss of serine proteas

298 To uncover the mechanism whereby stress-induced changes in

299 Our study uncovers a mechanism whereby co-existing cytoplasmic tra

300 Our study uncovers the pathogenic mechanism whereby absence of RPG