ライフサイエンスコーパス: underlie

1 ses associated with chronic inflammation and underlie a variety of poorly treatable pathologies.

2 nection with an abnormal cortical event that underlies a neurological disorder.

3 is may be an important part of the mechanism underlying ADPKD pathogenesis.

4 The diagnosis of stroke, its underlying aetiology, theranostic strategies, recurrence

5 -quality genomes is also discussed, since it underlies all secondary genomic analyses such as RNA seq

6 c, biological, and symptomatic heterogeneity underlying Alzheimer's disease (AD) requires a deep unde

7 Among neurobiological mechanisms underlying antidepressant properties of ketamine, struct

8 ected movement along actin is unclear as the underlying architecture of the local actin network is of

9 at all nontransverse patterns share a common underlying array architecture, having a core unimodal pe

10 The genetic causes underlying ASD in approximately half of patients remain

11 o that unusual reactions can be compared and underlying assembly-line logic can emerge.

12 hich are often not easily deducible from the underlying atomistic system.

13 a new therapeutic strategy to attenuate the underlying autoimmune pathogenesis of ophthalmopathy.

14 The underlying basis of thalassemia pathology is the prematu

15 Addressing how neural circuits underlie behavior is routinely done by measuring electri

16 A (miRNA) regulation on the genetic programs underlying behavior remain largely unexplored.

17 y be core components of the genetic programs underlying behavioral control in other animals too.

18 processes without detailed knowledge of the underlying biochemical reactions.

19 s in African ancestral populations; yet, the underlying biologic mechanisms remain uncertain.

20 in functions, this study reveals a potential underlying biological mechanism of a novel risk gene for

21 ex congenital heart disease (CHD), while the underlying biological mechanism remains unclear.

22 The underlying biological mechanism was shown to be interfer

23 eric alpha/beta subunit-containing receptors underlie both synaptic and tonic glycinergic currents.

24 we understand better the immunologic factors underlying both original antigenic sin and negative anti

25 pithelium, but the molecular mechanisms that underlie breast epithelial hierarchy remain ill-defined.

26 The immunological mechanisms underlying C-IRIS are incompletely defined and no reliab

27 ibing the activation and inactivation of the underlying calcium channels and correctly identified the

28 y matched by demographic characteristics and underlying cancer diagnosis (as applicable) to non-HCT 2

29 auditory brainstem circuits might be a major underlying cause of the auditory processing deficits in

30 Studies on underlying causes and therapeutic interventions seem war

31 lume irrespective of the molecular mechanism underlying cell swelling.

32 se mediators on neutrophil functions and the underlying cellular mechanisms involved.

33 Here, we explore the underlying cellular mechanisms.

34 stitial fluid from the brain and may reflect underlying cerebral small vessel disease (SVD).

35 ve and quantitative neural correlates of the underlying chronic disease.

36 l, drug reward, and addictive behaviors, but underlying circuit mechanisms have been poorly explored

37 synchrotron methods to understand the modes underlying clinically significant tissue reactions to Co

38 otential cell/circuit underpinnings that may underlie cognitive impairments in offspring of mothers t

39 itional functional traits or other processes underlying community assembly.

40 ith smaller effect sizes, such as those that underlie complex diseases.

41 Heterogeneity in genetic architecture underlying complex traits and diseases, while broadly ac

42 pends on (1) the severity of the anemia, (2) underlying condition(s), and (3) patient-related factors

43 unique opportunity to examine the mechanisms underlying conscious perception.

44 Finally, genomic regions underlying correlations among allocation metrics were ma

45 cessary precursor to fully understanding the underlying data and subsequent results of these types of

46 Identification of the underlying defect in Ig-MPGN could lead to improved trea

47 by lesional macrophages, but the mechanisms underlying defective efferocytosis and its possible link

48 ge-activated currents might be the mechanism underlying defective repetitive firing.

49 l tube defects and polydactyly; however, the underlying defects in cilia signaling and the function o

50 in up-regulation of key photoreceptor genes underlies delayed outer segment elongation and possibly

51 , a lichenoid infiltrate was observed in the underlying dermis, predominantly composed of CD3+ T cell

52 gnaling, and uncovers a ciliary protein that underlies development and human disease.

53 s is surprising, as defective gene silencing underlies developmental abnormalities and disease.

54 rences in gene expression and signaling that underlie differences in function between MBCs and naive

55 Herein, we investigated factors underlying differential sensitivity to IgG-mediated arth

56 l require continued research into mechanisms underlying disease prevention, pathogenesis, progression

57 on, in association with the treatment of the underlying disease, represents a valid approach that can

58 However, the underlying disease-causing mechanism remains uncertain.

59 pathophysiology and the regulatory networks underlying disease.

60 study (Translational Research Investigating Underlying Disparities in Acute Myocardial Infarction Pa

61 Loss of this organization underlies disturbed insulin secretion kinetics in T2D.

62 driven by a functional relationship with the underlying DNA sequence.

63 ugh sigmaCC -->sigma*CF interactions are the underlying driving force for the origin of the observed

64 Underlying drug resistance and the acquisition of drug r

65 ffective strategies that mine data to reveal underlying dynamics.

66 timulation to correct maladaptive plasticity underlying dysfunctional decision-making related to neur

67 diverse mAbs and the disulfide connectivity underlying E1E2 native conformation.

68 tectures and tubulin-binding properties that underlie each family's ability to promote microtubule po

69 It is thus important to understand underlying early molecular events.

70 lar connections between endo- and epicardium underlie EBW and that a slight degree of endo-epicardial

71 tu measurements of the behavioral rules that underlie ecological rates in other natural systems.

72 ide a consistent and complete picture of the underlying ensembles.

73 nset and thereby implying differences in the underlying etiology.

74 rovide important insights into the mechanism underlying eukaryotic transcription termination.

75 ons were graded according to the strength of underlying evidence and potential benefit gained by earl

76 e and adult life-history phases, and for the underlying expression of genes related to morphological

77 shed light on the network architectures that underlie external task engagement, and highlight selecti

78 ses provide insights into the generalizable, underlying features of epitope-specific repertoires and

79 the attack trajectories of animals, but the underlying feedback laws have remained obscure.

80 perceptual signals into a categorical format underlying flexible behavior.

81 The elucidation of the mechanisms underlying folate action has been challenging.

82 s sarcopenia and osteopenia as indicators of underlying frailty may provide complementary prognostic

83 d HCN channel opening, the precise mechanism underlying gating remains poorly understood.

84 rstanding of the complex molecular mechanism underlying Gaucher disease and the regulation of beta-gl

85 stigation to elucidate the precise mechanism underlying gene-length dependent changes in expression i

86 ield component, but our understanding of the underlying genes and mechanisms is limited.

87 mage traits during the last century, but the underlying genes are unknown.

88 recision cancer medicine seeks to target the underlying genetic alterations of cancer; however, it ha

89 cture and function provide insights into the underlying genetic architecture of cardiac structure and

90 ofoundly improve understanding of mechanisms underlying genetic associations.

91 ences, but there is also evidence to support underlying genetic variance.

92 This variability likely reflects underlying genetic, environmental and neuropathological

93 however, the phenotypic characteristics and underlying genetics associated with amelanotic melanoma

94 ies have investigated the complex mechanisms underlying GR functions.

95 ting in order to determine the number of the underlying habitats; and (2) an unsupervised pattern rec

96 A further understanding of the mechanism underlying HBoV1 helper-dependent AAV2 replication may a

97 ponses, is a fundamental brain function that underlies hemodynamic-based functional brain imaging tec

98 ied in many human cancers, but the mechanism underlying how hPOT1 mutations initiate tumorigenesis ha

99 provided by pretreatment tumor size and the underlying immune recruitment dynamics.

100 s this important decision heuristic and what underlies individual differences have hitherto remained

101 s for WRA can be improved by considering the underlying infection burden of the population and by ass

102 The search for general processes that underlie intelligence in nonhumans has followed two stra

103 Our findings elucidate the molecular basis underlying inter-segment interactions in rotaviruses, pa

104 ced T cell gene networks contributing to the underlying intestinal inflammation.

105 ctional and anatomical organization that may underlie intrinsic auditory regionalization.SIGNIFICANCE

106 ficult to uncover the molecular process that underlies its antibacterial activity.

107 annels, thus suggesting a possible mechanism underlying KCC2-dependent insulin release.

108 Patients with underlying kidney disease or abnormal serum creatinine l

109 eaking has little apparent connection to the underlying lattice, as evidenced by the small magnitude

110 To identify genomic loci underlying LBM, we performed a gene-based genome-wide as

111 We identified 3 mechanisms underlying local progression in the remnant pancreas: (1

112 quency synaptic function and inhibiting both underlies loss of synaptic transmission via massive vesi

113 tions and reveals the biochemical mechanisms underlying m(6)A function in the cell.

114 contribute to the epigenetic plasticity that underlies malignant transformation.

115 c variation in the physical condition of the underlying mantle where majority of arc magmas are gener

116 folding is toxic to cells and is believed to underlie many human diseases, including many neurodegene

117 in intrinsic excitability have been shown to underlie many learning and memory processes, little is k

118 g, and prefrontal dysfunction is believed to underlie many of the cognitive and behavioural phenotype

119 The genetic variation underlying many heritable forms of cardiovascular diseas

120 system to decipher the molecular mechanisms underlying MCS formation.

121 The site of pain depends on the pain type or underlying mechanism (eg, painful cramps, nociceptive pa

122 r hepatitis C virus (HCV) infection, but the underlying mechanism and relevance to other viruses or i

123 Thus, the underlying mechanism for the observed enhancement remain

124 fective to attenuate muscle atrophy, but the underlying mechanism has not been fully investigated.

125 locks HIV-1 replication in DCs, although the underlying mechanism is still unclear.

126 on prior to Tau aggregate formation, but the underlying mechanism is unclear.

127 self can modulate AD pathology, although the underlying mechanism is unclear.

128 s or pathological hypokalaemia, however, the underlying mechanism is unclear.

129 e generation, the tissue distribution or the underlying mechanism of clonal expansion in vivo.

130 Herein, we further investigate the underlying mechanism of this conformational rearrangemen

131 We reveal that the underlying mechanism of this intriguing gas-like adhesio

132 To better understand the underlying mechanism of this process, we performed genet

133 that promotes diabetic nephropathy, but the underlying mechanism remains incompletely understood.

134 utants develop cerebellar malformations, the underlying mechanism remains unknown.

135 ent exocytosis of TRPC6 is thought to be the underlying mechanism, and recent studies showed that sKl

136 However, the underlying mechanisms and disease relevance of such lyso

137 f some mRNAs at cellular protrusions but the underlying mechanisms and functional roles are not known

138 5 induces apoptosis in cancer cells, but the underlying mechanisms are largely undefined.

139 nriched within cellular protrusions, but the underlying mechanisms are largely unknown.

140 read throughout the animal kingdom but their underlying mechanisms are not well characterized.

141 idespread in diverse bacterial lineages, the underlying mechanisms are still incompletely understood.

142 in the gastrointestinal tract; however, the underlying mechanisms for this are not well understood.

143 o suppress quantum corrections to reveal the underlying mechanisms governing the resistivity.

144 Nevertheless, the underlying mechanisms governing this hepatoprotection re

145 Yet, the complexity of the underlying mechanisms has constrained previous studies t

146 tor KIR2DS1, providing new insights into the underlying mechanisms involved in KIR2DS1-related disord

147 Underlying mechanisms likely include overexpression of S

148 These findings help to shed light on the underlying mechanisms of cardiac alternans especially wh

149 Understanding the role and the underlying mechanisms of NRs in the context of energy ba

150 The goal of this study is to determine the underlying mechanisms of sequential energy transfer from

151 Although the underlying mechanisms remain unclear, the existence of h

152 s during stomatal closure is documented, the underlying mechanisms responsible for dark-induced cytos

153 ring folding were studied to investigate the underlying mechanisms resulting in its unique properties

154 Our results reveal some of the underlying mechanisms that make PPR wetlands biogeochemi

155 ntestinal I/R-induced injury and, if so, the underlying mechanisms, remain unknown.

156 how comparative analysis of ADRs can reveal underlying mechanisms.

157 e of attractiveness-related biases and their underlying mechanisms.

158 d plant species Phragmites australis and the underlying mechanisms.

159 sudden death, but little is known about the underlying mechanisms.

160 nd serious psychiatric syndrome caused by an underlying medical condition.

161 tient deaths occurred, all deemed related to underlying medical conditions.

162 long-term potentiation (LTP) are thought to underlie memory formation.

163 However, the underlying metabolic effects of opioid withdrawal and re

164 r contributor to the complex mechanisms that underlie metastasis in colorectal cancer and a potential

165 Such events may underlie METH- exacerbated neurocognitive dysfunction in

166 -seeking by hydrated flies and together they underlie moist-seeking by dehydrated flies.

167 le periods rather than the consequence of an underlying molecular mechanism measuring a fixed amount

168 re known to promote cell death; however, the underlying molecular mechanisms facilitating caspase-3 a

169 We aimed to clarify the underlying molecular mechanisms of suspected RM in the s

170 eural circuits via synaptic dysfunction, the underlying molecular mechanisms remain poorly understood

171 leading to cardiovascular disorders, but the underlying molecular mechanisms remain poorly understood

172 A better understanding of the underlying molecular mechanisms would be of help, but un

173 roanatomical substrate for investigating the underlying molecular mechanisms.

174 n area of anatomical convergence in circuits underlying motivated behavior, but it remains unclear ho

175 To further understand the underlying neural processing of TFS, experiments in huma

176 The underlying neurobiological mechanisms of this genetic in

177 ropagation of misfolded conformations of tau underlies neurodegenerative diseases, including Alzheime

178 ationship between childhood symptoms and the underlying neurodevelopmental processes remains unclear.

179 ibutes to tissue damage, and what mechanisms underlie neurological and muscular pathologies that toxo

180 Accurately predicting the underlying neuropathological diagnosis in patients with

181 gain of function but also on the mechanisms underlying nonmutational wtp53 inactivation, which might

182 t the dynamics and the regulatory mechanisms underlying nuclear movements in root epidermal cells rem

183 sue in response to a positive energy balance underlies obesity and occurs through both hypertrophy of

184 ritance echo a suite of core principles that underlie organic Darwinian evolution but also extend the

185 Genetic defects in DNA repair underlie other neurodegenerative disorders (eg, ataxia-t

186 This region may underlie our ability to understand the structure of our

187 y represents an endophenotype with differing underlying pathogenesis in different subjects.

188 encing alone is not sufficient to reveal the underlying pathogenic mutation.

189 Although the underlying pathophysiology is not well understood, inhib

190 However, the neural circuit mechanisms underlying persistent neuronal encoding within this netw

191 cal spreading depression (CSD) is likely the underlying phenomenon of aura.

192 We show that many loci of small effect underlie phenotypic variation, and identify five genomic

193 nict-1 locus could define a novel mechanism underlying phoretic interactions.Nematodes use a charact

194 he concept of resonant SEIRA and discuss the underlying physics, particularly, the resonant coupling

195 al architectures of chaos generation and the underlying physics.

196 iving cells and faithfully reconstituted the underlying processes in vitro.

197 infection represents an important mechanism underlying progressive CD4(+) T cell depletion in vivo.

198 that does not disrupt treatment regimens for underlying psychiatric illnesses.

199 rms of RCM have been reported, and mutations underlying RCM have been identified in genes that govern

200 ach country who were differentiated by their underlying reasons for their propensity to get circumcis

201 ies presented here thus reveal the mechanism underlying redox-regulation of AP-1 Fos/Jun transcriptio

202 imes suggests decreased tissue water content underlying regional gray matter decreases.

203 A novel predictor of bullying may be underlying regional weather conditions (i.e., climate).

204 To clarify the underlying regulatory mechanisms, we developed three bio

205 perspective of both communities, outline the underlying research challenges, and suggest directions t

206 Mechanisms underlying reservoir stability are unclear.

207 derstanding of the molecular mechanisms that underlie restless legs syndrome could lead to new treatm

208 Unlike in mouse models, the mechanisms underlying SAg-associated immunosuppression in humans ar

209 How animals achieve this task, and its underlying sensory basis, is still unknown.

210 e auditory system is likely reflected in the underlying set of genes involved in auditory function.

211 cal advances, it is expected that mechanisms underlying several disease states involving the interact

212 network in order to elucidate the mechanisms underlying signal integration.

213 Although much is known about the underlying signaling pathways, it remains unclear how ma

214 ural selection in shaping the processes that underlie social information use, using a suite of experi

215 Following an introduction to the mechanisms underlying spatial navigation and how they relate to gen

216 conditioning, we show that prediction errors underlying stimulus-stimulus learning can be blocked beh

217 y metrics have been widely used to infer the underlying structural connectivity in neuronal networks.

218 d a decision-making task which had a similar underlying structure with the exception that it was not

219 to reveal the neurocomputational mechanisms underlying subjective cost-benefit valuation across diff

220 ed to intercalate between monolayer MoS2 and underlying substrates or in the interlayer space of thic

221 erimental studies to identify the mechanisms underlying such antecedent effects.

222 been considered to be the primary mechanism underlying such impedance based microflow sensors.

223 rs to carefully evaluate the characteristics underlying such models when trying to identify a suitabl

224 reviously investigated for variants that may underlie SUDY pathophysiology.

225 tion and architecture, many basic mechanisms underlying target recognition and cleavage are highly co

226 nes and identify multiple signaling pathways underlying taste cell differentiation and taste stem/pro

227 e monkey to study the neural mechanisms that underlie the behavioral consequences of transcranial alt

228 f nuclear receptors involved in adipogenesis underlie the differences between OP9 and 3T3-L1 cells; h

229 protein-induced changes in the rRNA dynamics underlie the hierarchy of 30S assembly and simplify the

230 seq, we characterized the gene programs that underlie the ILC2 activation state.

231 enetic alterations and genomic reprogramming underlie the innate and adaptive resistance of RISC cell

232 This may underlie the mechanisms by which cells sense directional

233 ar changes may critically, and more broadly, underlie the neural computational dysfunction prototypic

234 te to hair cell development, but it does not underlie the normal MT current.

235 ng the systemic and cellular mechanisms that underlie the regulation of iron homeostasis and its diso

236 idbrain monoaminergic nuclei, is believed to underlie the transient inhibition of DA neurons attribut

237 teraction as a key bi-functional switch that underlies the central logic of PCP signaling during morp

238 N-terminal fragments (encoded by HTT exon 1) underlies the disease pathology in mouse models and that

239 ecting already available cognitive processes underlies the maturation of cognition during adolescence

240 regation of a small number of known proteins underlies the most common human neurodegenerative diseas

241 ding protein MYH9, and the coding gene FOXE1 underlies the predisposition to PTC triggered by rs96551

242 the zirconia nodes closer together, and also underlies the sintering resistance of these clusters dur

243 ntracellular gate and the selectivity filter underlies the structural basis for gating in potassium i

244 his study, we aimed to reveal the mechanisms underlying the behavioral action of NPS, and present a c

245 s, providing new insight into the mechanisms underlying the beneficial metabolic effects induced by V

246 re we report the recovery of the binary star underlying the classical nova eruption of 11 March AD 14

247 dom components of the developmental programs underlying the Drosophila olfactory system harbor a disp

248 The mechanism underlying the effect of ILT3.Fc on tumor cell growth in

249 To shed light on the processes underlying the emergence of electromotility, we focused

250 rgy minimization) are (i) general principles underlying the evolution of the diversity of biological

251 need to investigate the molecular mechanisms underlying the evolution of therapy-induced resistance o

252 Here we explored the genetic mechanism underlying the expression of discrete mating strategies

253 However, the mechanisms underlying the formation, storage, and expression of suc

254 A major mechanism underlying the genetic diversification of influenza A vi

255 While the mechanisms underlying the high-level expression of GATA1 in maturin

256 n this process, but the molecular mechanisms underlying the influence of experience on interneuron pl

257 Understanding the deformation mechanisms underlying the mechanical behavior of materials is the k

258 We show that the mechanism underlying the observed changes in cBLI signal is mediat

259 ate clinically relevant molecular mechanisms underlying the pathogenesis of most monogenic forms of N

260 ls share similarities of neural organization underlying the perception of odors, taste, vision, sound

261 a general essential feature of the mechanism underlying the phenomenon of allergenicity.

262 The precise molecular mechanism underlying the regulation of early B cell lymphopoiesis

263 The molecular mechanisms underlying the regulation of MCU, in conditions requirin

264 study, we elucidated the neuronal mechanism underlying the response at an anatomical, functional, an

265 or non-mutational drug resistance mechanisms underlying the survival of residual cancer 'persister' c

266 , a cortical region that generates sequences underlying the temporal progression of the song.

267 id tumors and schwannomas but the mechanisms underlying the tumor type specificity are unknown.

268 ifferences in tumor immunogenicity appear to underlie their relative importance.

269 , as well as about the molecular machineries underlying them.

270 ystems of differing steric bulk unpicked the underlying thermodynamic factors controlling the reactio

271 What are the principles that underlie these observed patterns?

272 The neural pathways underlying these abilities are unknown.

273 However the mechanisms underlying these changes are unknown.

274 To unravel the molecular mechanism underlying these disorders and investigate possible phar

275 The structural basis underlying these distinctive transport mechanisms is puz

276 statins on clinical outcomes, the mechanisms underlying these effects remain elusive.

277 respective of the exact rates and mechanisms underlying these findings, they illustrate that the burd

278 tes host metabolism, but specific mechanisms underlying these interactions remain poorly understood.

279 Several clever structural features underlie this amazing phenomenon.

280 ays involved in structural plasticity likely underlie this form of translation-independent memory.

281 ate the dynamic transcriptional changes that underlie this process, we applied a single-cell RNA-sequ

282 Endothelial dysfunction may underlie this; however, the association of endothelial n

283 ty in observational studies, but the factors underlying this association are uncertain.

284 the cell signaling and organellar mechanisms underlying this capability are unclear.

285 its fundamental importance, the mechanism(s) underlying this defect remains unclear.

286 The mechanisms underlying this increased risk are not known.

287 cardiometabolic disease, yet the mechanisms underlying this link remain obscure.

288 en developed and point to central mechanisms underlying this phenomena, such as increased activation

289 moving object, though the neural mechanisms underlying this process remain poorly understood.

290 We review the computational theory underlying this proposal and the empirical evidence to s

291 Some mechanisms underlying this quantitative signal processing have been

292 her in women than in men, but the mechanisms underlying this sex bias are unknown.

293 We examined two putative genetic mechanisms underlying this sex bias: sex-specific heterogeneity and

294 To determine the mechanism underlying this sexually dimorphic difference in clinica

295 r (ccRCC); however, the molecular mechanisms underlying transformation and the requirement for additi

296 Gain-of-function mutations in iRHOM2 underlie Tylosis with oesophageal cancer (TOC), characte

297 ogen cycling complexity and possible factors underlying variability of N2O fluxes, driven in part by

298 Understanding mechanisms underlying variable metabolic requirements of different

299 The molecular mechanisms underlying vascular inflammation and associated inflamma

300 gesting that distinct genes or sets of genes underlie visual and olfactory system phenotypes.