ライフサイエンスコーパス: underscore

1 They underscore a fundamental plant-water feedback pathway th

2 In particular, they contribute to underscore a potential genetic risk factor for cardiovas

3 Prompted by these results, which underscore a potentially significant role of 5RK in exoc

4 These findings underscore a previously unknown function for GCN2 phosph

5 st response to bacterial infection, and they underscore a role for Sts in regulating functionally rel

6 Altogether, our data underscore a unique replication-dependent repair pathway

7 Our findings underscore a wider role for U1 snRNP in splicing regulat

8 This underscores a growing realization that species richness

9 This underscores a previously unknown role of DNA damage repa

10 on in particular on the YY1-bound enhancers, underscoring a crucial role for YY1 in enhancer regulati

11 r results reveal a novel regulatory pathway, underscoring a previously unknown and interconnected key

12 L1 is a novel regulator of ciliogenesis thus underscoring a regulatory loop between FSTL1 and cilia.

13 Our study underscores an evolutionarily conserved interaction betw

14 sation and P metabolism in K. mikimotoi, and underscore AP activity is not the exclusive indicator of

15 The importance of motor learning was underscored as the changes were much smaller in a contro

16 curacy, precision, and calibration curve was underscored by calculations performed with peak areas, r

17 l local motions at the edges of the strands, underscored by enhanced (15)N R1rho relaxation rates, re

18 ting epidermal-differentiation genes, a role underscored by its pathogenic mutations in esophageal sq

19 The approach's validity is underscored by RXR::VDR motif sequence being predictive

20 the functional competence of the eye, a fact underscored by the devastating toll of excessive inflamm

21 f these simple carbamate-type auxiliaries is underscored by the ease of installation and removal, the

22 Its importance is underscored by the effects of its mutation in Hirschspru

23 ysiological importance of the IKS channel is underscored by the existence of mutations in human Kv7.1

24 f primary ELN dysfunction to pathogenesis is underscored by the mutations in more than 35 ELN-related

25 to Alzheimer's disease (AD) pathogenesis, as underscored by the recent identification of immune-relat

26 The domestication of plants is underscored by the selection of agriculturally favorable

27 The importance of these molecules is underscored by their newly recognized roles in inflammat

28 The large sizes of these tissue reservoirs underscore challenges in developing 'HIV cure' strategie

29 ce in sensitive cells during co-cultivation, underscoring complex interactions in bacterial communiti

30 Our findings underscore essential actions for ESCRT-III in membrane r

31 Taken together, our results underscore fibulin-3 as a novel extracellular signal wit

32 The importance of this mechanism is underscored in 5q- syndrome, a macrocytic anemia caused

33 Importantly, the three pathways were underscored in the pathophysiology of psychiatric disord

34 he physiological functions of the insula and underscore its pathological roles in psychiatric and neu

35 aceted roles of YAP in PDAC pathogenesis and underscore its promise as a therapeutic target for this

36 4 expression and susceptibility to apoptosis underscored its central regulatory role.

37 Miz-1 functions in other cellular processes, underscoring its importance in the cell.

38 tures known to be geographically widespread, underscoring its potential environmental significance.

39 een identified as substrates of the complex, underscoring its role as a non-coding RNA processing/deg

40 asthma have provided biological insight and underscored possible mechanistic differences between ind

41 iated with distinct aspects of LV mechanics, underscoring potential differential effects along specif

42 ween apo NCX_Mj-WT and NCX_Mj-5L6-8, thereby underscoring specific conformational patterns owned by t

43 These findings underscore that DAT is critical for DA neurotransmission

44 These results underscore that DNA methylation is modulated by environm

45 We also underscore that the principle and strategies put forward

46 Finally, our results underscore that we should not ignore Bd as a potential t

47 The results underscore that, even if the Paris targets are realized,

48 produce the hallmarks of this reprogramming, underscoring that rewiring, rather than arrhythmia, is a

49 The structural insights underscore the adaptability of fusicoccin, predicting mo

50 In broader terms, our results underscore the caution that, unless far-field contaminat

51 Genetic and functional studies underscore the central role of JAK/STAT signaling in mye

52 tildrakizumab, guselkumab, and risankizumab) underscore the central role of these cytokines as predom

53 Overall, these findings underscore the clinical relevance of AKT-independent pat

54 Overall, our results underscore the complex heterogeneity of malignancies and

55 Our findings underscore the complex interplay between antigenic drift

56 diates that result in amyloid formation, and underscore the complex nature of correlations between li

57 gy deprivation can impact Sirt1 activity and underscore the complex nature of Sirt1 structure and reg

58 These results underscore the complex relationship between BMI and CAP

59 The data underscore the complexity of glioma infiltration.

60 Our results underscore the complexity of the effects of activating m

61 ts of mechanosensitive lamin-A and retinoids underscore the convergent synergy of insoluble and solub

62 Not only does this study underscore the critical role that these proteins play in

63 These results underscore the debate on the true nature, electrostatic

64 Our results also underscore the developmental caveats of using antibiotic

65 ghly resistant K. pneumoniae infections, and underscore the effect humoral immunity has on evolving d

66 simultaneously during early 60S assembly and underscore the enormous complexity of 60S synthesis.Ribo

67 These data underscore the functional importance and cell type speci

68 These effects underscore the functional role of BKCa current in limiti

69 Our findings underscore the great potential of CYP716s as a source fo

70 These findings underscore the immense microbial diversity and functiona

71 Our results underscore the importance for benthic ecology of reducin

72 These studies underscore the importance of a thorough stepwise approac

73 These results underscore the importance of accounting for behavioral-h

74 These findings underscore the importance of achieving widespread delive

75 Our results underscore the importance of anticipating not only chang

76 sion of the early development of cancer, and underscore the importance of ATF3 in the maintenance of

77 Results underscore the importance of avoiding overinterpretation

78 Our results underscore the importance of carefully monitoring metabo

79 The findings underscore the importance of cell contractility and tiss

80 nt in blood flow in straight tubes, and they underscore the importance of considering realistic physi

81 These findings underscore the importance of considering the potentially

82 nic potential of retroviral gene therapy and underscore the importance of cytoreductive conditioning

83 are relevant to other tropical countries and underscore the importance of developing a policy mix tha

84 These results underscore the importance of documenting head injuries e

85 These findings underscore the importance of early detection in high-ris

86 These results underscore the importance of electron donor and chloroet

87 ty of NHC-catalyzed kinetic resolutions, and underscore the importance of electrostatic interactions

88 These findings underscore the importance of ensuring that improved seps

89 Therefore, our data underscore the importance of finely regulated endosomal

90 genetic basis for microbial adaptability and underscore the importance of hosts as selective agents t

91 Our findings underscore the importance of IL-10R signaling in prevent

92 In addition, our findings underscore the importance of miRNAs in posttranscription

93 Our findings underscore the importance of molecular noise, arising no

94 These results underscore the importance of multi-band physics, Coulomb

95 Our findings underscore the importance of national surveillance and u

96 These findings underscore the importance of not terminating resuscitati

97 The study findings underscore the importance of organizational safety pract

98 Together, the results underscore the importance of parkin activation by the PI

99 These findings underscore the importance of past as well as current res

100 gnaling in maintaining lung homeostasis, and underscore the importance of resident macrophages in mod

101 Our findings underscore the importance of retroviral structural prote

102 Our present results underscore the importance of RUNX1-p53-CBFB regulatory l

103 Our results underscore the importance of species specific studies an

104 These findings underscore the importance of specific combinations of tr

105 These findings underscore the importance of STAT5 tetramers in maintain

106 These findings underscore the importance of thalamocortical activation

107 These results underscore the importance of the caudate nucleus in rela

108 The term "exposome" was coined in 2005 to underscore the importance of the environment to human he

109 Our results underscore the importance of the human fibrinolytic syst

110 In this commentary, we underscore the importance of the psychology of relative

111 These results underscore the importance of the simultaneous assessment

112 These phenomena underscore the importance of tracking all neuronal linea

113 Our results underscore the importance of understanding the interplay

114 Our results underscore the importance water safety management in wat

115 Our findings underscore the increasing appreciation for the importanc

116 These results underscore the instructive role of intrinsic mechanisms

117 ssue of the Journal of Clinical Microbiology underscore the limitations of pneumococcal vaccines that

118 Collectively, these data not only underscore the multiple pathways that contribute to main

119 ps in data, modeling, and communication that underscore the need for an open, shared network to frame

120 e of bariatric surgery for treating NASH and underscore the need for clinical trials in this area.

121 quiescent, chemoresistant state and thereby underscore the need for combinatorial approaches to impr

122 scale differences in phenological strategies underscore the need for considering regional climate his

123 To underscore the need for continued empirical attention to

124 Temporal changes in MATS coverage underscore the need for continued monitoring of antigen

125 y for transmission in a direct contact model underscore the need for continued study of H7 subtype vi

126 e modest efficacy, have safety concerns that underscore the need for effective peripherally acting dr

127 Results underscore the need for much wider adoption of field-sca

128 These findings underscore the need for novel therapies and suggest that

129 Our findings underscore the need for ongoing research in this area bu

130 These data underscore the need for sustained efforts in increasing

131 tor-based regimens in sub-Saharan Africa and underscore the need to accelerate the study and approval

132 These findings underscore the need to account for individual glacier ge

133 lnerability of black Americans, our findings underscore the need to address the potential impact of m

134 The findings presented here underscore the need to evaluate a nonlive RSV vaccine ca

135 n dynamics and ecological interactions, that underscore the need to further understand how trait-medi

136 g principles of precision medicine in stroke underscore the need to identify, value, organise and ana

137 These findings underscore the need to improve treatment of patients wit

138 Therefore, we underscore the need to incorporate behavioral ecology in

139 Our analyses underscore the need to quantify the transmissibility of

140 Importantly, our results underscore the need to sample across taxonomic groups to

141 onnectivity of layer 5 pyramidal neurons and underscore the persistent impact of MD on synapse loss i

142 upture in the absence of both Cd36 and Mertk underscore the physiologic significance of phagocytosis

143 Findings underscore the potential benefit and risks to be aware o

144 rm species due to fire regime, these results underscore the potential for a reduction in boreal produ

145 esponse to EPO in weight control in mice and underscore the potential for gender specific EPO action

146 Collectively, these data underscore the potential for PDAC resistance to even the

147 These findings underscore the potential importance of self-regulated in

148 Our results underscore the potential importance of the ERK/MAPK path

149 he colony biofilm model to pathogenicity and underscore the potential of cbb3-type oxidases as therap

150 ings uncover facets of CAR immunobiology and underscore the potential of CRISPR/Cas9 genome editing t

151 These constructs underscore the potential of SNAs in regulating immune re

152 These findings underscore the potential relevance of spinel-type oxides

153 These findings underscore the potential role and regulation of PFKP in

154 These findings underscore the potential utility of recombinant herpesvi

155 vide new insights into retromer assembly and underscore the power of using pathogens to discover dise

156 These results underscore the prevalent requirement of active CRMP2 for

157 Taken together, these data underscore the requirement for mechanistic studies to id

158 se a model to account for these effects, and underscore the roles of actin organization in determinin

159 Our results underscore the significance of expanding residential dev

160 Overall these results underscore the significance of mitochondrial energy meta

161 These findings underscore the strong interaction between historical dem

162 Current treatments are mainly palliative and underscore the unmet clinical need for improved therapie

163 Collectively, our results underscore the utility of combining comprehensive bioche

164 Our findings underscore the utility of revisiting unexploited antibio

165 Our results underscore the value of considering indirect effects of

166 The findings underscore the value of spatial analysis in identifying

167 hat can interact directly with G4 DNA, which underscored the complex regulatory networks involved in

168 CANCE STATEMENT: Recent genetic studies have underscored the emerging role of microglia in Alzheimer'

169 of a devastating disease such as cancer has underscored the need for developing comprehensive panels

170 aning of protective immunity with time, have underscored the need to develop strategies to enhance th

171 These experiences underscored the need to optimize preparation for and res

172 This underscores the added importance of delineating underlyi

173 The NOMPC architecture underscores the basis of translating mechanical force in

174 t factors associated with optimal use, which underscores the benefits of team-based care to support g

175 ae, and Pseudomonas aeruginosa-reported here underscores the broad utility of our approach, complemen

176 This trial underscores the burden undertaken by caregivers as they

177 This work underscores the capacity for small molecule-like tunabil

178 id formation is initiated with beta2m, which underscores the complexity of how these structures assem

179 This review underscores the conformational flexibility of porphyrino

180 Our study underscores the critical importance of fine-tuned presyn

181 This underscores the ecological diversity of derived pliosaur

182 ical strains to colonize multiple body sites underscores the habit flexibility of initial colonists,

183 This work underscores the importance of acute risks of high temper

184 to vesicoureteral reflux in newborns, which underscores the importance of apoptotic modulation durin

185 del presents avenues for future research and underscores the importance of carefully considering chan

186 ests that these exposures may be ongoing and underscores the importance of continued biomonitoring an

187 Our research underscores the importance of feedback regulation in gen

188 of receptors for a single microbial product underscores the importance of host-microbe interactions

189 This work underscores the importance of Pax9-dependent Wnt signali

190 vidence of rainforest occupation by AMH, and underscores the importance of reassessing the timing and

191 This study underscores the importance of STING in the control of HS

192 e spatial and temporal signal processing and underscores the importance of studying the dynamics of s

193 The unique impact of the isoquinoline ligand underscores the importance of subtle matching between li

194 This finding underscores the importance of targeting high-school STEM

195 Here, we review research that underscores the importance of this bottom-up control at

196 ve care unit studies was not observed, which underscores the importance of timing when administering

197 ting potent inhibition of retrovirus release underscores the importance of understanding fundamental

198 This study underscores the importance of understanding the role of

199 t but significant contributions to virulence underscores the incremental contributions to fitness of

200 necessarily generate more potent PROTACs and underscores the key roles played by the conjugation.

201 s at birth and in the early postnatal period underscores the limitations of tasking community health

202 arch into circadian modulation of reward and underscores the methodological importance of accounting

203 This outbreak underscores the need for a national surveillance system

204 H7N2 virus in the northeastern United States underscores the need for continuous surveillance of emer

205 This study underscores the need for development of additional corre

206 Our study underscores the need for long-term clinical trials in ad

207 icity of the NF-kappaB signaling pathway and underscores the need for more selective strategies to th

208 imate change-mediated vector range expansion underscores the need for research aimed at developing me

209 Our study further underscores the need to interpret altered TSPO binding i

210 The review underscores the overlap of experiments and theory, rangi

211 This study underscores the photophysical diversity of the M-(PM')n-

212 This study underscores the potential importance of incorporating ox

213 The demonstrated ability underscores the potential of MTSERS to perform 3D spectr

214 Our study underscores the potential of strategic renewable energy

215 heir association with the ocean temperatures underscores the potential predictability of these events

216 This study underscores the potentially important role that IVB inje

217 respond non-uniformly to a structural change underscores the power of combining synthetic and biologi

218 fect of DNA nicking on histone eviction that underscores the powerful potential of topological relaxa

219 This pathophysiological sequence of events underscores the role of cardiovascular disease as a cont

220 GLP-1R signaling controls energy balance and underscores the role of the LDTg in integrating energy b

221 ng protein to regulate DNA accessibility and underscores the role of the novel mechanism by which nuc

222 This work underscores the structural polymorphisms originated from

223 This finding underscores the surprising specificity of TCRs for their

224 This study underscores the therapeutic potential of PrP(C) deletion

225 olecular, population and community-wide data underscores the tightly coordinated in situ metabolism o

226 candidate virulence factors that we discover underscores the urgent need to halt the advance of patho

227 aration in all of the metrics studied, which underscores the utility of biomimetic nanoparticle-based

228 nd evolution of our succinct total synthesis underscores the utility of long-avoided aryne intermedia

229 D (SCM), is mislocalized in ugt80B1 mutants, underscoring the aberrant root epidermal cell patterning

230 etic pathways during translation elongation, underscoring the ability of E-site codons to modulate th

231 nd enhances sensitivity to oxidative stress, underscoring the cellular requirement for functional per

232 y 260 million people are infected worldwide, underscoring the clinical and socioeconomic impact of th

233 directly predictable from single stressors, underscoring the complex and trait-specific mechanisms o

234 'targeted' inhibitors on antitumor immunity, underscoring the complex effects resulting from diverse

235 nd on the endogenous L1 nucleotide sequence, underscoring the complexity of L1 regulation.

236 53-dependent and -independent tumorigenesis, underscoring the complexity of MDM2 posttranscriptional

237 on, cytoskeletal tension, and cell adhesion, underscoring the complexity of signaling feedback follow

238 in viruses leading to antigenic variability, underscoring the complexity of vaccine selection for bot

239 has seen only minimal therapeutic advances, underscoring the critical need for new treatments.

240 ral similarities with alphaherpesvirus VP22, underscoring the evolutionary importance of MT cytoskele

241 t one third of all primary lymphedema cases, underscoring the existence of additional genetic factors

242 t because of the resampling of large clones, underscoring the feasibility and relevance of understand

243 -Bi combination was too unstable to isolate, underscoring the fragility of these linkages.

244 was accompanied by increased PDLIM5 levels, underscoring the functional importance of PDLIM5 for pro

245 containing mRNA isoforms from polyribosomes, underscoring the functional relationship between transla

246 upled with tissue demand and in aging flies, underscoring the generality of this mechanism.

247 ife experiences of the child and the family, underscoring the high prevalence of symptom burden, the

248 young adult stages and across tasks, thereby underscoring the importance of better understanding the

249 in mother's breast milk seed the infant gut, underscoring the importance of breastfeeding in the deve

250 on in macrophages compared with hepatocytes, underscoring the importance of cell type-specific differ

251 KDSR cause defective ceramide biosynthesis, underscoring the importance of ceramide and sphingosine

252 er rather than simply as mechanical lockers, underscoring the importance of considering disulfide bon

253 the most common genetic risk factor for PD, underscoring the importance of delineating the mechanism

254 poradically infect humans and other mammals, underscoring the importance of developing an H10 vaccine

255 y results in a median survival of 14 months, underscoring the importance of developing effective new

256 he majority of these findings were distinct, underscoring the importance of distinct contributing fac

257 s as patients progress to longstanding PsAF, underscoring the importance of early intervention.

258 g T cell sensitivity to activation via PGE2, underscoring the importance of FRCs in shaping the suppr

259 aste dominated N and P inputs, respectively, underscoring the importance of household actions in infl

260 ed than that in the higher energy analogues, underscoring the importance of noncovalent interactions

261 of unicellular and multicellular genotypes, underscoring the importance of social and ecological con

262 not be observed in studies of pure cultures, underscoring the importance of synthetic microbial commu

263 and even be fatal in high-risk individuals, underscoring the importance of understanding how the vir

264 led to timely public health recommendations, underscoring the importance of using systematic methods

265 d by a reduction in activation-gate opening, underscoring the important role of the surrounding lipid

266 iduals develop a subsequent malignant tumor, underscoring the important role that host and environmen

267 nd mortality in patients with HFrEF on GDMT, underscoring the important synergy of addressing hemodyn

268 al and hydrological connections among zones, underscoring the interconnected nature of these ecosyste

269 s are found to be rounded and not polarized, underscoring the key role played by the nonlinear mechan

270 stitutes a significant public health threat, underscoring the need for a Chlamydia-specific vaccine.

271 patients fail to respond to these therapies, underscoring the need for improvement with combination t

272 g to development-distinct effects on growth, underscoring the need for novel risk assessment strategi

273 ost candidate off-target sites will be rare, underscoring the need for prescreening of patients throu

274 uthern and eastern Africa and Latin America, underscoring the need for routine national HIV drug-resi

275 ifferent backgrounds are joining this field, underscoring the need for unity regarding the use of ter

276 eds light on cellular membrane biophysics by underscoring the nonequilibrium metabolic status of livi

277 sting is non-diagnostic in >50% of patients, underscoring the ongoing need for DCM gene discovery.

278 oxidative status within the lipid membrane, underscoring the opportunity to illuminate the physiolog

279 Underscoring the opposing effects of Tia1 deletion and l

280 dies, and they rapidly decompose in solution underscoring the paucity of uranium phosphido complexes.

281 s reveals substantial mechanistic diversity, underscoring the phylogenetic divergence of related CRIS

282 ctive in treatment-resistant mood disorders, underscoring the potential importance of the glutamaterg

283 he efficacy of a chemotherapeutic substance, underscoring the potential of the system for drug screen

284 bility by using single-cell signatures, thus underscoring the prognostic value of our approach.

285 ising novelty in the bacterial tree of life, underscoring the promise of future discovery.

286 ce of the porphyrias is clinically variable, underscoring the role of additional causative, contribut

287 itional effects of precipitation shortfalls, underscoring the role of broadly based economic developm

288 tes that were strongly correlated with kappa underscoring the role that mineralogy, including salts,

289 ial families displaying similar colonization underscoring the suitability of this technique to evalua

290 functional interaction between Spin and Lpp, underscoring the systemic nature of lipid perturbation i

291 urn injury requires satellite cell activity, underscoring the therapeutic potential of satellite cell

292 ality in patients with compromised immunity, underscoring the urgent need for new antifungal agents.

293 conservation between Drosophila and humans, underscoring the usefulness of Drosophila in modeling it

294 l regulator of beta2 adrenoceptor signaling, underscoring the value of a dynamic view of receptor fun

295 ctively bind and/or process these structures underscores their biological relevance.

296 e genes are commonly seen in blood disorders underscores their critical roles and highlights the need

297 eter settings markedly affected performance, underscoring their importance for program reproducibilit

298 llowing specific developmental trajectories, underscoring their relevance to brain organization and f

299 a transcriptional coactivator, our findings underscore two distinct but complementary mechanisms by

300 tic conditions ([Ru(bpy)3](2+)/S2O8(2-)) was underscored with a wide range of further analytical meth