ライフサイエンスコーパス: understand

1 ence on interneuron plasticity remain poorly understood.

2 the origin of this shift in chemistry is not understood.

3 nd in disease states, remains only partially understood.

4 ome (ARDS), joblessness is common but poorly understood.

5 5 during silica precipitation remains poorly understood.

6 ses, the role of the daughter remains poorly understood.

7 acokinetics following dermal exposure is not understood.

8 specific age and sex groups are still poorly understood.

9 how these factors influence ToxR is not yet understood.

10 s accounting for hypersensitivity are poorly understood.

11 that orchestrate these events remain poorly understood.

12 mics of coastal marine food webs is not well understood.

13 golipids in differentiated cells is not well understood.

14 rmined during differentiation remains poorly understood.

15 mediating delamination are, however, poorly understood.

16 nd events leading to extrusion are not fully understood.

17 circadian photoreception is currently poorly understood.

18 isms of this suppression remain incompletely understood.

19 r, the regulation of HSJ1 function is little understood.

20 ocess, however, have not yet been completely understood.

21 f its fascinating injection machinery is not understood.

22 products within infected cells are not well understood.

23 enesis of these complications remains poorly understood.

24 ic activity, but how they function is poorly understood.

25 chanism by which bacteria divide is not well understood.

26 on in prostate cancer patients are not fully understood.

27 rs that influence expression are not clearly understood.

28 maintained in the adult brain remains poorly understood.

29 igodendrocyte development has not been fully understood.

30 infiltrating lymphocytes (TILs) are not well understood.

31 reason for this gender disparity is not well understood.

32 was observed in Arabidopsis, but is not well understood.

33 pro-angiogenic effect of IL-37 are less well understood.

34 role in neurodegeneration are not yet fully understood.

35 rsus memory differentiation are incompletely understood.

36 ndependent cancer risk factor, remain poorly understood.

37 control its proapoptotic function are poorly understood.

38 specific, epigenetic pattern is still poorly understood.

39 d autoimmune disorders is complex and poorly understood.

40 lutionary conserved diversity remains poorly understood.

41 e loss of tolerance to gluten remains poorly understood.

42 SLC25A46-related neuropathies are not fully understood.

43 t sensing of physical stimuli remains poorly understood.

44 hat promote tumor formation are incompletely understood.

45 gulatory small RNAs (sRNAs) are incompletely understood.

46 chanism of action of GM-CSF in EAE is poorly understood.

47 these structural features are not completely understood.

48 us, although the mechanisms are incompletely understood.

49 ors of late-life depression are still poorly understood.

50 y distributed, cryptic environment is poorly understood.

51 ty and breast cancer formation remain poorly understood.

52 structure under confinement is far less well understood.

53 underlying mechanisms are still incompletely understood.

54 ropic effects for reasons that are not fully understood.

55 s vesicle fusion and plasticity are not well understood.

56 of morphogenic signals by cells is not well understood.

57 sia (BPH), the etiology of which is not well understood.

58 systemic metabolic consequences are far less understood.

59 such widely varying conditions are not fully understood.

60 different cultures and thereby foster mutual understanding.

61 sical and chemical properties, but little is understood about the morphology and dynamics of these po

62 We explore how the understanding and control of the characteristic physical

63 srupt and cross cell membranes is needed for understanding and controlling polycation-membrane intera

64 ogy reported here may be used to improve the understanding and prediction of El Nino/La Nina events a

65 Understanding and treating this disease remains a challe

66 rs regulating target selectivity is not well understood and often overlooked when developing clinical

67 hanisms behind this protection are not fully understood, and not all patients with HF respond favorab

68 he HTLV-1 particle structure is still poorly understood, and previous studies analyzed viruses produc

69 Especially poorly understood are the very early stages of protein folding,

70 athogenic relationships, but is often poorly understood at the molecular level.

71 egion by focusing on the role of voyaging to understand better the core elements that produced the ob

72 It is essential that we understand better the immunologic factors underlying bot

73 ation in proteins and cells is important for understanding biological function.

74 Understanding biological invasions is crucial for their

75 lection, adopting a connectomics approach to understanding brain network architecture, employing adva

76 triggered by these various agents is poorly understood, but it might explain the differential respon

77 how associated genetic variants can lead to understanding causal mechanisms, and to disentangling re

78 transcription factors, allowing us to better understand cell-type-specific regulation of inflammation

79 cale metabolic networks (GEMs) can assist in understanding cellular metabolism.

80 oping organs requires coordinated but poorly understood changes in epithelial cell-cell adhesion and

81 Therefore, understanding circuit mechanisms that drive behavioral d

82 perspective, our analysis provides tools for understanding complex dependencies in the collision prob

83 hwater shrimp genus Caridina is still poorly understood, despite its vast distribution - from Africa

84 imprinting with particular regards to cancer understanding, diagnosis and therapy.

85 of SIRM to cancer metabolism and its use in understanding drug actions.

86 al transport properties in TMDs are not well understood due to the challenges in characterizing aniso

87 s over time, this method offers an avenue to understand dynamic cell behavior, including processes su

88 This finding is important in understanding EV71-host cell interactions and has potent

89 particles arguably explain a range of poorly understood experiments in gated graphene structures at l

90 The potential to understand fundamental biological processes from gene ex

91 eterometallic poly(f-block) chains to better understand fundamental electronic structure in the f-blo

92 Understanding gene regulation and function requires a ge

93 This is central to understanding geometric control of genetic programs invo

94 p of rare designed hexasaccharides will help understand HCII function.

95 To better understand HIV-1 pathogenesis and the evolution of the v

96 flagellar filament has long been studied to understand how a polymer composed of a single protein ca

97 One goal of structural biology is to understand how a protein's 3-dimensional conformation de

98 population worldwide highlights the need to understand how aging promotes CVD in order to develop ne

99 st at alarming rates and it is imperative to understand how communities assemble if we have to preven

100 To better understand how loss of D2-family dopamine receptors can

101 e mode expansion theory is developed to help understand how the gradient metasurface tailors the inci

102 Further research is needed to understand how these noncardiac complications may affect

103 To understand how these receptors distinguish ACh and Cho,

104 ntracellular calcium dynamics of VSMC and to understand how variation in protein levels that arise du

105 These observations allow us to understand how ZIF-8 crystals self-assemble and the subs

106 to population growth rate (lambda) is key to understanding how animal populations will respond to cha

107 This work exposes a strategy for understanding how biophysical characteristics contribute

108 Understanding how broadly neutralizing antibodies (bnAbs

109 Understanding how MkMPs target, deliver cargo and alter

110 d with preclinical AD.SIGNIFICANCE STATEMENT Understanding how risk factors for Alzheimer's disease (

111 Thus, understanding how sex impacts immunity requires the eluc

112 structing the lineage of cells is central to understanding how the wide diversity of cell types devel

113 hogenesis of these diseases, it is not fully understood how distinct GJB2 mutations result in hearing

114 ompared to normal cells, but it is not fully understood how WRN deficiency leads directly to telomere

115 constructing ancient mobility is crucial for understanding human strategy at exploiting temporally an

116 It is well suited for understanding hypoxia-mediated mechanisms in cancer dise

117 Understanding in detail the processes involved in HCMV r

118 This Review presents current understanding in wound healing and regeneration as two d

119 ng this system is significant, and should be understood in detail.

120 ary molecular mechanisms remain incompletely understood in plants and animals.

121 d in suspension cultures, but remains poorly understood in substrate-dependent cells.

122 Chemical bond energies can then be understood in terms of stabilization caused by spin-coup

123 new era, characterized by the confluence of understanding LSCs and the ability to target them, is sh

124 bundance of isoprene SOA in the troposphere, understanding mechanisms of adverse health effects throu

125 Understanding mechanisms underlying variable metabolic r

126 embranous subunit of V-ATPase or have poorly understood mechanisms of action.

127 Understanding MGD pathophysiology and its relationship t

128 atus of microbiome research as it relates to understanding obesity from the perspective of both commu

129 iated with HLA class I-DSA could improve our understanding of ABMR and be useful for diagnostic or th

130 ms and tissue types will further improve our understanding of ancient DNA breakdown dynamics.

131 ochar use highlight the need for an improved understanding of biochar's impacts on soil NO emissions.

132 A major gap in our understanding of biodiversity-ecosystem function relatio

133 themselves is important for our mechanistic understanding of cell biology.

134 in therapeutic development, and fundamental understanding of cellular behavior during hypoxia.

135 rofiling with great potential to improve our understanding of cellular heterogeneity through discover

136 findings have important implications for the understanding of compartmentalized cAMP signalling.

137 human pancreatic beta-cells, broadening our understanding of cytokine-induced beta-cell apoptosis in

138 scovery and could lead to more comprehensive understanding of disease etiology.

139 ch is absolutely essential for improving our understanding of disease mechanisms contributing to risk

140 emarkably common in early human embryos, our understanding of early embryonic somatic mutations is ve

141 possible model, given the available data and understanding of ecological structures.

142 bon budget in China's forests and for better understanding of effects of climate and stand characteri

143 An understanding of fluid transport through porous material

144 eighboring mesenchymal partners provides new understanding of how different cell types are maintained

145 ng cardiac specification is critical for our understanding of how heart formation is initiated during

146 ctin-mitochondria interaction, enhancing our understanding of how mitochondria properly localize in a

147 either FTD or NCL, in part because of a poor understanding of how mutations in genes such as GRN cont

148 Results extend the understanding of how organic carbon and nitrite loads mo

149 this single-cell approach provides a better understanding of how prostate cancer cells respond heter

150 behavior and pathology, but we lack a basic understanding of how sex differences in the human cerebe

151 Together, these models provide a biophysical understanding of how stem cell scaling is maintained dur

152 individual isoforms, necessitating a deeper understanding of how the distinct transcriptional progra

153 esistance that would be helpful for a better understanding of how to manage antibiotic-resistant bact

154 The results extend our understanding of human CSF flux and open important clini

155 nnotate the human genome and to increase the understanding of human disease.

156 revolutionizing approaches to gain a better understanding of human diseases.

157 pproaches to contribute substantially to the understanding of important human diseases.

158 A better understanding of intrauterine conditions that influence

159 With our evolving understanding of intrinsic resistance, people have succe

160 of centriole components have accelerated our understanding of its assembly, function, evolution, and

161 ostic tools for Alzheimer disease and better understanding of its neurobiology.

162 We discuss how growing understanding of key anatomic sanctuaries for the virus

163 a valuable resource to advance our molecular understanding of meiosis.

164 To gain understanding of MRN in cancer, we engineered mice with

165 Our finding can enrich our understanding of nanoscale energy transfer in molecular

166 brings a new perspective to molecular-scale understanding of neurodegenerative diseases.

167 dimers as the key antigenic target, and deep understanding of neutralizing mechanisms, multiple vacci

168 Disease heterogeneity and poor understanding of pathogenic mechanisms hampers the ident

169 An improved understanding of pathogenic pathways in AKI may identify

170 mitations, there has been an increase in the understanding of pathophysiology and important risk fact

171 ans.This study sought to advance the current understanding of placental vitamin D metabolism and its

172 h sufficiently long values of T2 requires an understanding of precisely how the position of nuclear s

173 hways within the brain and provide a limited understanding of primary odor detection.

174 s, significant progress has been made in the understanding of proteasome assembly, structure, and fun

175 Thus, this study contributes to our understanding of protein function within different Norov

176 However, a general understanding of RNA localization has been hindered by a

177 Critically, our understanding of ROS-mediated PTP oxidation is not yet s

178 have important implications for fundamental understanding of RVFV virulence.

179 A more thorough understanding of sex-specific cardiovascular differences

180 Increased understanding of specific diabetes phenotypes and genoty

181 e manner, with the aim of obtaining a deeper understanding of stem cell fate computation, in order to

182 There is limited understanding of the associations between systemic medic

183 n, it is imperative that we develop a better understanding of the basic biology of this parasite and

184 ion of gene models will not only further our understanding of the biological processes of this plant

185 ation and transmigration, which advances our understanding of the complex contribution of CtsB to ang

186 In one such approach, an understanding of the distal and geometric relationships

187 This study significantly enhances our understanding of the EAV carrier state in stallions by u

188 This study sought a better understanding of the effect of the definition of T2MI on

189 void this issue is hindered by an inadequate understanding of the electrically-induced wrinkling defo

190 1):1-9) was an important contribution to the understanding of the epidemiology of cardiovascular dise

191 To gain a deeper understanding of the evolution of gene transcription in

192 This study facilitates our understanding of the fate and transformation of IAPP in

193 Our understanding of the frequency of large earthquakes at t

194 during development, contributing to improved understanding of the genetic etiology of familial tooth

195 ications may be accomplished through a sound understanding of the hemodynamic and physiological conse

196 An improved understanding of the heterogeneity of presenting symptom

197 w the EBV life cycle and discuss our current understanding of the immune response to EBV in healthy,

198 An evolving understanding of the immunopathogenesis of multiple scle

199 described by Glorius et al., builds a broad understanding of the impact of individual functional gro

200 s, patients and their families, for a better understanding of the impact this disease has on a person

201 Our results provide a fundamental understanding of the information-theoretic nature of the

202 scover new catalysts by obtaining a detailed understanding of the initial steps of CO2 electroreducti

203 ant use in biotechnology, we lack a detailed understanding of the kinetics of nucleic acid hybridizat

204 aking place throughout the tropics, improved understanding of the magnitude and spatial variation in

205 Taken together, our results extend the understanding of the molecular mechanism of transcriptio

206 Advances in understanding of the molecular mechanisms that underlie

207 However, until recently, deficiencies in our understanding of the nature of these cell populations, c

208 There is growing understanding of the oncogenic and tumor suppressive fun

209 dedness, implying a fundamental shift in our understanding of the ontogenesis of hemispheric asymmetr

210 past decade has seen significant advances in understanding of the pathogenesis and progression of lun

211 light how such improvements enable a greater understanding of the pathogenesis of disease and the rea

212 Our understanding of the pathophysiological basis of chronic

213 he lower urinary tract and contribute to our understanding of the pathophysiology of urinary retentio

214 s lack effective therapies despite increased understanding of the role factors such as an overactive

215 Our work has the potential to improve our understanding of the role of global methylation in human

216 Our work provides an improved understanding of the role of ionic correlations in NP as

217 ere is a fundamental gap in our quantitative understanding of the role of local ECM size and arrangem

218 nits and antigenic epitopes to gain a better understanding of the technology at a molecular level.

219 e climates, which will require a mechanistic understanding of the trade-offs that determine trait div

220 unity-based surveillance allows for a better understanding of the true burden and seasonality of dise

221 th, is an important yield component, but our understanding of the underlying genes and mechanisms is

222 A better understanding of the underlying molecular mechanisms wou

223 A fuller understanding of the virus life cycle is important to ai

224 Understanding of their development is of high interest f

225 A fuller understanding of these effects and the characterization

226 Further understanding of this differential regulation will enhan

227 aminergic neurons and contribute to a better understanding of this functionally complex group of neur

228 n be experimentally validated to improve our understanding of what triggers and maintains the growth

229 m(6)A) RNA modifications in mRNA requires an understanding of when and where in the life of a pre-mRN

230 g several mouse models, that will deepen our understanding, open avenues for research and provide an

231 ote sensing (Light Detection and Ranging) to understand orangutan movement in disturbed and fragmente

232 ell interactions and has potential impact on understanding other enterovirus-host cell interactions.

233 Understanding phase behaviors of nanoconfined water has

234 Understanding physical phenomena peculiar to nanoconfine

235 This poorly understood population is referred to as minimal residual

236 rotein unfolding mechanisms are critical for understanding protein functions inside cells, de novo pr

237 These insights provide a foundation for understanding recognition of full-length proteins by HDA

238 drug resistance and provides a framework for understanding resistance dynamics in single cells.

239 Regardless of whether one understands stereotypes as generic or statistical belief

240 It is commonly understood that a potential for skillful climate predict

241 To understand the adhesive secretions of P. shermani, its c

242 In order to better understand the boundaries within which roughness operate

243 This contemporary review first strives to understand the diverse roles of immune cells implicated

244 More research is needed to understand the effectiveness of screening and treatment

245 lectively, our data provides new insights to understand the evolutionary relationships between MULE,

246 th the SR protein splicing factor (SRSF1) to understand the foundation of these opposing effects in t

247 To understand the genetic architecture of how these two org

248 Recent studies have helped to understand the genetic basis of clonal evolution and rel

249 ory behavior, emphasizing the need to better understand the implications of ALAN for migratory bird p

250 s spectrometry experiments were performed to understand the ion-molecule growth mechanism of small ac

251 of high-throughput data has been profiled to understand the mechanism of complex diseases.

252 To better understand the mechanism of Prp activity, we analyzed Pr

253 To better understand the mechanisms responsible for the ppDIO-indu

254 We used synchrotron methods to understand the modes underlying clinically significant t

255 To understand the role of oncogenic KRAS in CRC, we enginee

256 To better understand the secoiridoid biosynthesis pathway, we gene

257 We have developed a mathematical model to understand the significance of altered levels of SERCA,

258 significant research efforts are underway to understand the spread and the unique pathogenesis of thi

259 This region may underlie our ability to understand the structure of our social world and navigat

260 findings may have important implications to understanding the behaviour of these cells in vivo.

261 Understanding the biologic role of N(6)-methyladenosine

262 iting membrane of the retina is essential to understanding the cause of rhegmatogenous retinal detach

263 Understanding the complex connections between the histor

264 Understanding the deformation mechanisms underlying the

265 Future studies should focus on understanding the determinants of sex differences in reh

266 of migratory species faces the challenge of understanding the ecological requirements of individuals

267 Understanding the fine details of this synergy has prove

268 ols, thus providing a chemical framework for understanding the formation mechanism of S(0) aerosols i

269 l calcium utilization, a parallel advance in understanding the forms and quantities of mitochondrial

270 Our results underscore the importance of understanding the interplay among dispositional, develop

271 g provided important information for further understanding the life cycle of HCV and its interaction

272 This work provides a foundation for understanding the link between photonic and electronic p

273 Understanding the mechanisms by which immune-related eve

274 potential role of an inter-omics approach in understanding the metabolic pathways involved in IBD.

275 The results may help in understanding the origin of interface instabilities and

276 Nevertheless, TS8 is key to understanding the potential energy surface; there is a l

277 that DeBooster may provide new insights into understanding the regulatory functions of RBPs, includin

278 Understanding the relationship between known factors and

279 Understanding the relationship between the vitreous (in

280 age over the United States in summer require understanding the response of this dynamical and photoch

281 These results provide a foundation for understanding the role of multiple regulatory factors in

282 Understanding the role of this mechanism in specific cir

283 Replication studies and understanding the roles of these genes in keratoconus ar

284 gress has been made during the last years in understanding the SnRK1 signaling pathway, many of its c

285 Understanding the structural basis of immune recognition

286 Understanding the substrate specificity of these enzymes

287 ideal context to discuss recent progress in understanding the systemic and cellular mechanisms that

288 Understanding the ultrafast dynamics of electronically e

289 RNA-binding proteins (RBPs) is important for understanding their functional roles in gene expression

290 fore, their origin needs to be determined to understanding their role in these pathologies.

291 e on negative emotions, seemingly to try and understand them.

292 elated with serious complications in humans, understanding these processes may improve clinical manag

293 In seeking to understand this discrepancy, we find that many of the ba

294 To understand this process, we applied an unbiased quantita

295 To better understand this process, we studied fragment formation d

296 To understand this, we investigated transcriptomes using RN

297 anisotropic materials enables one to better understand three-dimensional orientation fields in chole

298 They are best understood when integrated into an evolutionary life his

299 avior relationship: behavioral work provides understanding, whereas neural interventions test causali

300 Critical to enhancing understanding will be disentangling the relative importa