ライフサイエンスコーパス: understanding

1 different cultures and thereby foster mutual understanding.

2 such constraints, but we have no systematic understanding about their extent and causes for any one

3 nd regrowth, with important implications for understanding adaptations to changing environments and f

4 We explore how the understanding and control of the characteristic physical

5 srupt and cross cell membranes is needed for understanding and controlling polycation-membrane intera

6 clinical care by advancing pathophysiologic understanding and fostering novel therapeutics.

7 ogy reported here may be used to improve the understanding and prediction of El Nino/La Nina events a

8 Understanding and treating this disease remains a challe

9 ation in proteins and cells is important for understanding biological function.

10 Understanding biological invasions is crucial for their

11 lection, adopting a connectomics approach to understanding brain network architecture, employing adva

12 relevant biomarker combinations pivotal for understanding cardiovascular disease.

13 how associated genetic variants can lead to understanding causal mechanisms, and to disentangling re

14 cale metabolic networks (GEMs) can assist in understanding cellular metabolism.

15 Therefore, understanding circuit mechanisms that drive behavioral d

16 iptome of individual cells is fundamental to understanding complex biological systems.

17 perspective, our analysis provides tools for understanding complex dependencies in the collision prob

18 imprinting with particular regards to cancer understanding, diagnosis and therapy.

19 of SIRM to cancer metabolism and its use in understanding drug actions.

20 This finding is important in understanding EV71-host cell interactions and has potent

21 he post-fusion conformation is important for understanding F protein function.

22 Understanding gene regulation and function requires a ge

23 This is central to understanding geometric control of genetic programs invo

24 to population growth rate (lambda) is key to understanding how animal populations will respond to cha

25 This work exposes a strategy for understanding how biophysical characteristics contribute

26 Understanding how broadly neutralizing antibodies (bnAbs

27 dylation has broad-reaching implications for understanding how homeostasis is achieved in regeneratin

28 Understanding how MkMPs target, deliver cargo and alter

29 accounts and discuss their implications for understanding how predictions of the sensory consequence

30 d with preclinical AD.SIGNIFICANCE STATEMENT Understanding how risk factors for Alzheimer's disease (

31 Thus, understanding how sex impacts immunity requires the eluc

32 Understanding how the brain extracts depth from two diff

33 Understanding how the paradox biases local observations

34 structing the lineage of cells is central to understanding how the wide diversity of cell types devel

35 rase holoenzyme has provided a framework for understanding how TR, TERT, and other proteins from cili

36 Thus, understanding how viruses evade or exploit macrophage fu

37 species specialized for animal pollination, understanding how wild pollinators utilize resources acr

38 Understanding human effects on microbial activity, fitne

39 ed pattern and highlights the need of better understanding human mobility and activity patterns under

40 constructing ancient mobility is crucial for understanding human strategy at exploiting temporally an

41 It is well suited for understanding hypoxia-mediated mechanisms in cancer dise

42 Understanding in detail the processes involved in HCMV r

43 This Review presents current understanding in wound healing and regeneration as two d

44 d its basal position in the monocot lineage, understanding its genome architecture could shed light o

45 new era, characterized by the confluence of understanding LSCs and the ability to target them, is sh

46 ical development along with implications for understanding mathematics disabilities.

47 bundance of isoprene SOA in the troposphere, understanding mechanisms of adverse health effects throu

48 Understanding mechanisms underlying variable metabolic r

49 Understanding MGD pathophysiology and its relationship t

50 atus of microbiome research as it relates to understanding obesity from the perspective of both commu

51 iated with HLA class I-DSA could improve our understanding of ABMR and be useful for diagnostic or th

52 ms and tissue types will further improve our understanding of ancient DNA breakdown dynamics.

53 he potential to improve our surveillance and understanding of asthma.

54 his, it has become apparent that our initial understanding of AT1R signaling is oversimplified.

55 ochar use highlight the need for an improved understanding of biochar's impacts on soil NO emissions.

56 A major gap in our understanding of biodiversity-ecosystem function relatio

57 A deeper understanding of Cas9 activation and its cleavage mechan

58 themselves is important for our mechanistic understanding of cell biology.

59 in therapeutic development, and fundamental understanding of cellular behavior during hypoxia.

60 rofiling with great potential to improve our understanding of cellular heterogeneity through discover

61 fill gaps in trait coverage will improve our understanding of changes in fine-root traits across spac

62 e alone remains poor, reflecting our limited understanding of cis-regulatory grammar and hampering th

63 er measurements of network structure and our understanding of collective phenomena.

64 findings have important implications for the understanding of compartmentalized cAMP signalling.

65 However, neuroscientific understanding of cross-modal plasticity following cochle

66 human pancreatic beta-cells, broadening our understanding of cytokine-induced beta-cell apoptosis in

67 In addition to extending our basic understanding of DATs and their role in cocaine reinforc

68 scovery and could lead to more comprehensive understanding of disease etiology.

69 ch is absolutely essential for improving our understanding of disease mechanisms contributing to risk

70 emarkably common in early human embryos, our understanding of early embryonic somatic mutations is ve

71 possible model, given the available data and understanding of ecological structures.

72 bon budget in China's forests and for better understanding of effects of climate and stand characteri

73 While an understanding of evolutionary processes in shifting envi

74 e exploited as a model system towards better understanding of F. pseudograminearum-wheat interaction.

75 requently begin in childhood/adolescence, an understanding of fear-extinction learning in children is

76 An understanding of fluid transport through porous material

77 or FND and PTSD symptoms and may advance our understanding of FND.

78 We review the current understanding of genomics in myelodysplastic syndromes (

79 clear and represent a major challenge to our understanding of glacial climates.

80 e efforts will contribute to a more complete understanding of global carbon and nitrogen cycling and

81 have important implications for our current understanding of healthy and adaptive brain processing.

82 ng cellular ATP production, and advances our understanding of how defective FA signaling contributes

83 eighboring mesenchymal partners provides new understanding of how different cell types are maintained

84 ng cardiac specification is critical for our understanding of how heart formation is initiated during

85 tuberculosis enzyme, augmenting our current understanding of how M. tuberculosis meets its nutrient

86 ctin-mitochondria interaction, enhancing our understanding of how mitochondria properly localize in a

87 either FTD or NCL, in part because of a poor understanding of how mutations in genes such as GRN cont

88 Results extend the understanding of how organic carbon and nitrite loads mo

89 this single-cell approach provides a better understanding of how prostate cancer cells respond heter

90 behavior and pathology, but we lack a basic understanding of how sex differences in the human cerebe

91 Together, these models provide a biophysical understanding of how stem cell scaling is maintained dur

92 Two recent papers advance our understanding of how the cancer genome evolves as the pr

93 individual isoforms, necessitating a deeper understanding of how the distinct transcriptional progra

94 tity of these genetic factors, improving our understanding of how they shape retinal function.

95 protein acetylation dynamics is critical for understanding of how this modification influences protei

96 esistance that would be helpful for a better understanding of how to manage antibiotic-resistant bact

97 The results extend our understanding of human CSF flux and open important clini

98 nnotate the human genome and to increase the understanding of human disease.

99 revolutionizing approaches to gain a better understanding of human diseases.

100 le and has begun making contributions to the understanding of human intestinal transport in normal ph

101 pproaches to contribute substantially to the understanding of important human diseases.

102 Further understanding of innate allorecognition and its conseque

103 A better understanding of intrauterine conditions that influence

104 With our evolving understanding of intrinsic resistance, people have succe

105 of centriole components have accelerated our understanding of its assembly, function, evolution, and

106 ostic tools for Alzheimer disease and better understanding of its neurobiology.

107 We discuss how growing understanding of key anatomic sanctuaries for the virus

108 A major bottleneck limiting understanding of mechanisms and consequences of cell dea

109 a valuable resource to advance our molecular understanding of meiosis.

110 This study provides new understanding of methanotrophic responses to methane sta

111 se questions will provide a greater level of understanding of miRNA biology and critical insights int

112 To gain understanding of MRN in cancer, we engineered mice with

113 However, our understanding of N deposition effects on microbial commu

114 Our finding can enrich our understanding of nanoscale energy transfer in molecular

115 brings a new perspective to molecular-scale understanding of neurodegenerative diseases.

116 wledge in these areas lag behind our current understanding of neuroprotection and vascular biology in

117 dimers as the key antigenic target, and deep understanding of neutralizing mechanisms, multiple vacci

118 e of interest and valuable data for a better understanding of OST-catalyzed N-glycosylation.

119 Disease heterogeneity and poor understanding of pathogenic mechanisms hampers the ident

120 An improved understanding of pathogenic pathways in AKI may identify

121 mitations, there has been an increase in the understanding of pathophysiology and important risk fact

122 nt paradigm shifts that have transformed our understanding of pediatric ocular motor disease at the p

123 Developing a greater understanding of personal and environmental factors that

124 ans.This study sought to advance the current understanding of placental vitamin D metabolism and its

125 h sufficiently long values of T2 requires an understanding of precisely how the position of nuclear s

126 hways within the brain and provide a limited understanding of primary odor detection.

127 s, significant progress has been made in the understanding of proteasome assembly, structure, and fun

128 Thus, this study contributes to our understanding of protein function within different Norov

129 Further understanding of risk factors, presentation, optimal man

130 However, a general understanding of RNA localization has been hindered by a

131 Critically, our understanding of ROS-mediated PTP oxidation is not yet s

132 have important implications for fundamental understanding of RVFV virulence.

133 A more thorough understanding of sex-specific cardiovascular differences

134 cies-level effects, ultimately improving our understanding of spatial community dynamics.

135 Increased understanding of specific diabetes phenotypes and genoty

136 e manner, with the aim of obtaining a deeper understanding of stem cell fate computation, in order to

137 A-4 pathway are therefore required to inform understanding of such immune dysregulation syndromes.

138 the production, manipulation, and scientific understanding of such remedies.

139 that can contribute to a more comprehensive understanding of symbiosis as a major driving force of e

140 There is limited understanding of the associations between systemic medic

141 n, it is imperative that we develop a better understanding of the basic biology of this parasite and

142 model mice in vivoSIGNIFICANCE STATEMENT Our understanding of the basis for intellectual impairment i

143 ivo functions of ADAR enzymes, informing our understanding of the biological importance of A-to-I edi

144 ion of gene models will not only further our understanding of the biological processes of this plant

145 physiological measurements, has improved our understanding of the biological responses during drought

146 ing deconstruction not only provide a better understanding of the cell wall architecture but also is

147 ation and transmigration, which advances our understanding of the complex contribution of CtsB to ang

148 Work with this model system has enriched our understanding of the cyclopropanation-Cope rearrangement

149 However, a detailed understanding of the DDR at a physiological level is lac

150 d midlife exposures will further advance our understanding of the disease.

151 In one such approach, an understanding of the distal and geometric relationships

152 ial to provide epidemiologists with a deeper understanding of the divergent pathways via which neighb

153 complementary methods which provide a better understanding of the domain wall motion.

154 ingle-molecule approaches have increased our understanding of the dynamic behavior of complex multipr

155 cial and ecological factors, and enhance our understanding of the dynamics of natural populations.

156 This study significantly enhances our understanding of the EAV carrier state in stallions by u

157 e effects in social species will improve our understanding of the ecological and evolutionary implica

158 eralisation and the development of a broader understanding of the ecology and evolution of mutualisms

159 genes duplicated in Trisomy 21 and a lack of understanding of the effect of disease pathology on the

160 This study sought a better understanding of the effect of the definition of T2MI on

161 void this issue is hindered by an inadequate understanding of the electrically-induced wrinkling defo

162 1):1-9) was an important contribution to the understanding of the epidemiology of cardiovascular dise

163 To gain a deeper understanding of the evolution of gene transcription in

164 This study facilitates our understanding of the fate and transformation of IAPP in

165 Our understanding of the frequency of large earthquakes at t

166 ved issue, even though it is critical to the understanding of the functional properties of MSMAs.

167 We have a limited understanding of the genetic and molecular basis of evol

168 during development, contributing to improved understanding of the genetic etiology of familial tooth

169 on sequencing has substantially enhanced our understanding of the genetics of primary brain tumors by

170 ications may be accomplished through a sound understanding of the hemodynamic and physiological conse

171 An improved understanding of the heterogeneity of presenting symptom

172 w the EBV life cycle and discuss our current understanding of the immune response to EBV in healthy,

173 An evolving understanding of the immunopathogenesis of multiple scle

174 described by Glorius et al., builds a broad understanding of the impact of individual functional gro

175 s, patients and their families, for a better understanding of the impact this disease has on a person

176 Our results provide a fundamental understanding of the information-theoretic nature of the

177 scover new catalysts by obtaining a detailed understanding of the initial steps of CO2 electroreducti

178 ant use in biotechnology, we lack a detailed understanding of the kinetics of nucleic acid hybridizat

179 aking place throughout the tropics, improved understanding of the magnitude and spatial variation in

180 n the scalability, stability and fundamental understanding of the materials.

181 ular homeostasis and therapy, our structural understanding of the MBS CC interaction with LZ PKG-1alp

182 As a next step toward an understanding of the mechanism by which IreB regulates r

183 tural products contain chlorine and thus, an understanding of the mechanism of its introduction into

184 Improved understanding of the mechanism of long-distance iron sig

185 A thorough understanding of the mechanism of this efficient enzyme

186 A further understanding of the mechanism underlying HBoV1 helper-d

187 Taken together, our results extend the understanding of the molecular mechanism of transcriptio

188 Advances in understanding of the molecular mechanisms that underlie

189 However, until recently, deficiencies in our understanding of the nature of these cell populations, c

190 There is growing understanding of the oncogenic and tumor suppressive fun

191 dedness, implying a fundamental shift in our understanding of the ontogenesis of hemispheric asymmetr

192 past decade has seen significant advances in understanding of the pathogenesis and progression of lun

193 light how such improvements enable a greater understanding of the pathogenesis of disease and the rea

194 The findings are important for the understanding of the pathogenesis of VTE.

195 Our understanding of the pathophysiological basis of chronic

196 A better understanding of the pathophysiology of DWMI is therefor

197 he lower urinary tract and contribute to our understanding of the pathophysiology of urinary retentio

198 explore several new ideas that could improve understanding of the phenotypic and genotypic difference

199 nst antithrombin polymerization, an improved understanding of the polymerogenic intermediates is cruc

200 xpression/function, could be improved by the understanding of the properties of the cancer secretome,

201 This article reviews recent advances in our understanding of the proteasome's multistep ATP-dependen

202 es in photosynthetic infrastructure, but our understanding of the relative effects of these factors a

203 s lack effective therapies despite increased understanding of the role factors such as an overactive

204 Our work has the potential to improve our understanding of the role of global methylation in human

205 Our work provides an improved understanding of the role of ionic correlations in NP as

206 ere is a fundamental gap in our quantitative understanding of the role of local ECM size and arrangem

207 nits and antigenic epitopes to gain a better understanding of the technology at a molecular level.

208 e climates, which will require a mechanistic understanding of the trade-offs that determine trait div

209 unity-based surveillance allows for a better understanding of the true burden and seasonality of dise

210 th, is an important yield component, but our understanding of the underlying genes and mechanisms is

211 A better understanding of the underlying molecular mechanisms wou

212 s comprehensive analysis extends our current understanding of the ureteric branch tip niche.

213 A fuller understanding of the virus life cycle is important to ai

214 Understanding of their development is of high interest f

215 reported RGGT inhibitors, rationally improve understanding of their structure-activity relationship.

216 A fuller understanding of these effects and the characterization

217 A precise understanding of these layers of control has important i

218 h over the previous decades has improved our understanding of this complex arrhythmia while unravelin

219 Further understanding of this differential regulation will enhan

220 aminergic neurons and contribute to a better understanding of this functionally complex group of neur

221 work opens the door to a detailed atomistic understanding of transformation reactions in even larger

222 ation of these interactions could expand our understanding of viruses and be exploited for epidemiolo

223 n be experimentally validated to improve our understanding of what triggers and maintains the growth

224 m(6)A) RNA modifications in mRNA requires an understanding of when and where in the life of a pre-mRN

225 These findings not only advance our understandings of the nano-bio interactions in kidneys b

226 g several mouse models, that will deepen our understanding, open avenues for research and provide an

227 ell interactions and has potential impact on understanding other enterovirus-host cell interactions.

228 The importance of understanding patient preferences for life-sustaining tr

229 Understanding phase behaviors of nanoconfined water has

230 Understanding physical phenomena peculiar to nanoconfine

231 cally unbiased yield estimates could play in understanding policy impacts.

232 iseases that offers a promising platform for understanding prion proteinopathies and advancing anti-p

233 rotein unfolding mechanisms are critical for understanding protein functions inside cells, de novo pr

234 These insights provide a foundation for understanding recognition of full-length proteins by HDA

235 drug resistance and provides a framework for understanding resistance dynamics in single cells.

236 Understanding species' responses to environmental change

237 Understanding such phenomena at the mechanistic level ca

238 robustly, but also in applications of ENM to understanding temporal dimensions of niche dynamics.

239 ing movement behaviors and ecology is key to understanding the adaptive evolution of locomotion.

240 findings may have important implications to understanding the behaviour of these cells in vivo.

241 Understanding the biologic role of N(6)-methyladenosine

242 of iPSCs and genome editing technologies for understanding the biological function of genes, and the

243 iting membrane of the retina is essential to understanding the cause of rhegmatogenous retinal detach

244 genes in patients with U-HAE is valuable for understanding the cause of the disease.

245 These findings have implications for understanding the causes and consequences of N limitatio

246 Understanding the complex connections between the histor

247 se sequence design and lays a foundation for understanding the control of two-level systems.Coherent

248 nes, and although advances have been made in understanding the cytokine milieu that promotes ILC2 res

249 Understanding the deformation mechanisms underlying the

250 Future studies should focus on understanding the determinants of sex differences in reh

251 f different risk factors, which will help in understanding the development of obesity in females.

252 Understanding the developmental pathway of these antibod

253 of migratory species faces the challenge of understanding the ecological requirements of individuals

254 Understanding the elements that control stability of the

255 of the fossil record as a major frontier in understanding the evolutionary assembly of modern verteb

256 Understanding the fine details of this synergy has prove

257 1623 1623 References 1624 Understanding the forces that shape the great amount of

258 ols, thus providing a chemical framework for understanding the formation mechanism of S(0) aerosols i

259 l calcium utilization, a parallel advance in understanding the forms and quantities of mitochondrial

260 Understanding the genomic complexity of bread wheat (Tri

261 Understanding the implications of distinct cell death pa

262 nfrared emission of SWCNTs are important for understanding the interaction between SWCNTs and lipid b

263 The data are useful for understanding the interactions of filoviruses with natur

264 Our results underscore the importance of understanding the interplay among dispositional, develop

265 g provided important information for further understanding the life cycle of HCV and its interaction

266 This work provides a foundation for understanding the link between photonic and electronic p

267 Understanding the mechanism behind this mutation can pro

268 Understanding the mechanisms by which immune-related eve

269 Understanding the mechanisms supporting tumor-initiating

270 potential role of an inter-omics approach in understanding the metabolic pathways involved in IBD.

271 action-relaxation model is developed towards understanding the microscopic mechanism of the phase tra

272 However, understanding the MRI enhancement mechanism in a multish

273 The results may help in understanding the origin of interface instabilities and

274 Understanding the physics of such motor-filament materia

275 Persulfidation provides a framework for understanding the physiological and pharmacological effe

276 Nevertheless, TS8 is key to understanding the potential energy surface; there is a l

277 mate-driven variables could be important for understanding the potential responses of coastal species

278 that DeBooster may provide new insights into understanding the regulatory functions of RBPs, includin

279 Understanding the relationship between known factors and

280 Understanding the relationship between the vitreous (in

281 age over the United States in summer require understanding the response of this dynamical and photoch

282 These results provide a foundation for understanding the role of multiple regulatory factors in

283 Understanding the role of this mechanism in specific cir

284 Replication studies and understanding the roles of these genes in keratoconus ar

285 or verifying SMSERS, and investigations into understanding the signal heterogeneities observed with S

286 gress has been made during the last years in understanding the SnRK1 signaling pathway, many of its c

287 Understanding the stem cell response to immune therapies

288 Understanding the structural basis of immune recognition

289 Understanding the substrate specificity of these enzymes

290 ideal context to discuss recent progress in understanding the systemic and cellular mechanisms that

291 ulk TMDs serve as an important benchmark for understanding the thermal conductivity of single- and fe

292 Understanding the ultrafast dynamics of electronically e

293 with phase-separated systems are critical to understanding the unusual behaviours of heterochromatin,

294 RNA-binding proteins (RBPs) is important for understanding their functional roles in gene expression

295 fore, their origin needs to be determined to understanding their role in these pathologies.

296 By understanding these inflammatory signaling processes, ne

297 elated with serious complications in humans, understanding these processes may improve clinical manag

298 Understanding thrombophilia in perinatal stroke informs

299 avior relationship: behavioral work provides understanding, whereas neural interventions test causali

300 Critical to enhancing understanding will be disentangling the relative importa