ライフサイエンスコーパス: understanding how

1 ver the last several years has been aimed at understanding how a cell with dozens of diguanylate cycl

2 Understanding how a force induces changes in the structu

3 Local structure and symmetry are keys to understanding how a material is formed and the propertie

4 ore, our model provides a rational basis for understanding how a mutation within the beta subunit of

5 Understanding how a protein which is predominantly expre

6 ious HIV-1 viral strains is challenging, but understanding how a subset of HIV-infected individuals d

7 Our study provides a structural basis for understanding how activators activate transcription thro

8 Understanding how active dendrites are exploited for beh

9 A great challenge in neuroscience is understanding how activity in the brain gives rise to be

10 e (R57K), are characterized with the goal of understanding how altered salt bridge interactions betwe

11 Understanding how ALV integration is regulated could fac

12 rocesses four-way junctions are involved in, understanding how and under what conditions these struct

13 Understanding how and when cells become different during

14 Understanding how and where transcription factors bind a

15 Understanding how and why animals regenerate complex tis

16 Understanding how and why language subsystems differ in

17 oral factors that constitute a first step to understanding how and why music literally moves us.

18 These results provide a framework for understanding how animal cells tune cortical flow throug

19 to population growth rate (lambda) is key to understanding how animal populations will respond to cha

20 Understanding how anthropogenic changes alter community

21 A4, with important possible implications for understanding how anti-CTLA4 immunotherapy mediates its

22 Here we review recent advances in understanding how antimalarials act and how resistance d

23 Understanding how antimicrobial peptides (AMPs) and othe

24 Understanding how anxiety affects generalization is key

25 se that novobiocin will be a useful tool for understanding how ATP hydrolysis is coupled to LPS trans

26 These results emphasize the importance of understanding how autophagy manipulation in a tumor cell

27 Understanding how bacteria affect plant health is crucia

28 Understanding how bacteria identify their social partner

29 Understanding how bacteria safely handle amyloidogenic p

30 Understanding how bacterial populations survive antibiot

31 e us some of the most useful information for understanding how batteries work, but it remains difficu

32 bulb presents an interesting case study for understanding how beta/gamma oscillations arise.

33 Understanding how biochemical networks lead to large-sca

34 sensitivity to dosage changes, we argue that understanding how biological robustness evolved makes th

35 This work exposes a strategy for understanding how biophysical characteristics contribute

36 ed during adult development is important for understanding how breast cancer arises.

37 Understanding how broadly neutralizing antibodies (bnAbs

38 Our work presents Zfp335 as a model for understanding how C2H2-ZF TFs may use multiple recogniti

39 tumor genetic heterogeneity is critical for understanding how cancers evolve and escape treatment.

40 Understanding how catalytic activity is distributed acro

41 Understanding how cells integrate multiple signaling pat

42 o and in silico data provide a framework for understanding how cells orient force generation, establi

43 ffect co-regulated groups of genes: a key to understanding how cellular pathways and processes are or

44 Understanding how changes in antibiotic consumption affe

45 Understanding how changes to the quality of habitat patc

46 oke exposure and provides a novel insight to understanding how cigarette smoke contributes to early c

47 c wiring diagram of the LON paves the way to understanding how circuits with reduced numerical comple

48 Understanding how climate warming will affect the demogr

49 Understanding how climatic variation affects animal popu

50 Computer simulations can aid in understanding how collective materials properties emerge

51 tes across developmental space and time, yet understanding how complexity and integration emerge from

52 Understanding how context is represented in the brain an

53 However, we are still far from understanding how cortical microcircuits encode and tran

54 V innate immune antagonists is essential for understanding how CoVs overcome host defenses and to max

55 calization and highlights recent progress in understanding how cytoskeletal motors orchestrate mRNA t

56 During the past 2 decades, understanding how DDR drives cancer development and cont

57 Understanding how decidual CD8(+) T cell (CD8(+) dT) cyt

58 Understanding how developing animals come to balance rem

59 Understanding how developmental and functional complexit

60 Thus, understanding how diabetes alters the ultimate mechanica

61 es that boost pre-existing T cell responses, understanding how different immune cells are affected by

62 Our findings have implications for understanding how discrete amygdalar CRF pathways modula

63 Understanding how disease symptoms develop may be a usef

64 Understanding how distinct parts of proteins produce coo

65 ped that this model provides a framework for understanding how diverse kinesins are tuned for their s

66 e to copy RNA into DNA has ramifications for understanding how DNA genomes evolved.

67 TD) learning model has been a cornerstone in understanding how dopamine RPEs could drive associative

68 Understanding how dopaminergic (DA) neurons of the subst

69 Understanding how drier climates may offset the balance

70 Understanding how drugs affect the immune system has con

71 sights gained from contemporary genetics for understanding how dysregulation of this powerful innate

72 boratory conditions, raising the urgency for understanding how each could be deployed in the real wor

73 Understanding how each of the many interneuron subtypes

74 Understanding how each transcript-specific distribution

75 Understanding how early haematopoietic development occur

76 Understanding how early-life cocaine exposure influences

77 irst line of evidence in a new framework for understanding how early-stage AD-associated neurodegener

78 Understanding how ECM components aid acute disease and p

79 eful tool for detecting and capturing dColl, understanding how ECM remodelling impacts disease progre

80 Understanding how edge misfit dislocations (MDs) form in

81 These results provide a framework for understanding how environmental influences like drugs ca

82 Understanding how epileptic seizures develop or identify

83 concentration (MIC) are dubious proxies for understanding how evolution will occur across drug envir

84 Understanding how faecal microbes respond to shifts in m

85 These results provide a context for understanding how feedback altered by aging or injuries

86 Understanding how FMRP regulates iontophoresis should re

87 Our findings suggest that understanding how frequently hydraulic fracturing operat

88 couple mRNA biogenesis events is crucial for understanding how gene expression is regulated.

89 ription factor binding sites is critical for understanding how gene transcription is regulated across

90 Understanding how gene-level mutations affect the bindin

91 tual confusions is a necessary first step in understanding how general intelligence evolved.

92 netic factors, emphasizing the importance of understanding how genes and drugs of abuse mechanistical

93 Understanding how genetic variation contributes to pheno

94 ciency has been linked to numerous diseases, understanding how genetic variation contributes to vitam

95 d across varied stimulus conditions requires understanding how glutamate, acetylcholine, and GABA sig

96 Understanding how guppy diets vary among communities is

97 g provided important information for further understanding how HCV evades host immunity to establish

98 ed mutations and provide a new framework for understanding how HECT ubiquitin ligases must be finely

99 Understanding how hepatitis C virus and other flavivirus

100 Understanding how heterogeneous cells within a multicell

101 dylation has broad-reaching implications for understanding how homeostasis is achieved in regeneratin

102 Understanding how hormones and genes interact to coordin

103 nic infectious and inflammatory disorders is understanding how host pattern recognition receptors (PR

104 bust, and biologically plausible approach to understanding how human cortical networks underpin indiv

105 Understanding how humans represent others' pain is criti

106 Understanding how humans see thus represents one of the

107 hese features may define unique insights for understanding how humoral responses target virions and f

108 Understanding how immune surveillance shapes the cancer

109 spectroscopy constitutes a first step toward understanding how impurities and contaminants interact w

110 data, ScaPD will be a valuable resource for understanding how individual signaling pathways are regu

111 e findings have theoretical implications for understanding how infants tune in to their local communi

112 Understanding how inflammasomes influence the outcome of

113 Understanding how inflammation affects each of these pro

114 s each of these processes may be crucial for understanding how inflammation affects iron status, indi

115 r splitting and the production of fuels, and understanding how interfaces between catalysts, photoabs

116 ortant patterning role of the anterior pole, understanding how it becomes localized during regenerati

117 ulence of N. ceranae has spurred interest in understanding how it differs from N. apis.

118 A1 and provide a quantitative framework for understanding how it discriminates between alternative c

119 T8SIA2 expression, providing a mechanism for understanding how it supports oligodendrocyte differenti

120 nitive science, but our focus has shifted to understanding how knowledge manifests in dynamic activit

121 of these initiatives depends critically upon understanding how landscape change affects key populatio

122 Understanding how leukocytes interact with NiV and cause

123 previous studies and provide a framework for understanding how lipid interactions regulate motifs to

124 In particular, understanding how local habitat conversion interacts wit

125 This information is critical to understanding how local processing in V1 relates to down

126 Understanding how magma is transferred from a magma rese

127 Understanding how many and what kind of posterior AR com

128 Understanding how materials that catalyse the oxygen evo

129 biorefining of chitin-rich waste streams to understanding how medically relevant fungi remodel their

130 Understanding how membrane proteins interact with deterg

131 Understanding how microglia recognize and prune synapses

132 signaling, our study narrows the search for understanding how microglia respond to active synapse mo

133 Understanding how microorganisms manipulate plant innate

134 on start sites (miRNA TSSs) is essential for understanding how miRNAs are regulated in development an

135 Understanding how MkMPs target, deliver cargo and alter

136 ism of allosteric switching is important for understanding how molecular machines work.

137 nimals, this organism has become a model for understanding how multicellularity evolved in the animal

138 These studies pave the way for understanding how mutations far from the kinase active s

139 s (LMICs), yet these factors are integral to understanding how national health agendas are establishe

140 Our framework provides a basis for understanding how natural environmental variation and hu

141 labile heme is of fundamental importance to understanding how nature preserves access to the diverse

142 Understanding how nerves spontaneously innervate tissues

143 Understanding how neural circuits process information re

144 Understanding how neural information is processed in phy

145 role of computational simulation studies in understanding how neuronal networks process biological s

146 arly common, with extensive implications for understanding how neurons encode the rapidly changing en

147 ior is controlled and general principles for understanding how neuropeptides organize neuronal activi

148 iochemical and structural framework to begin understanding how nuclear localized PRORPs recognize and

149 Understanding how often and the reasons why potential li

150 scuss the implications of these findings for understanding how organisms invest optimally in immunity

151 Mechanistic understanding how PARP inhibition induces cytotoxicity i

152 lation, the findings provide a mechanism for understanding how patients with metabolic stress and/or

153 Over the past two decades, understanding how perceptual decisions are made has beco

154 Understanding how phenotypic differences between males a

155 a potential biomarker for GSK3 activity, but understanding how phosphorylation regulates RABEP2 funct

156 Understanding how photosynthetic light-harvesting functi

157 ipating the impact of these changes requires understanding how plants are adapted to fire.

158 Understanding how plasticity is confined to critical per

159 Understanding how policies and practices change the feed

160 divergent selection and gene flow is key to understanding how populations adapt to local environment

161 accounts and discuss their implications for understanding how predictions of the sensory consequence

162 Understanding how previous exposure to influenza virus s

163 Understanding how prognosis varies across this heterogen

164 Understanding how protective Ab responses develop and ho

165 Understanding how Ras proteins are regulated is importan

166 ree is novel and fundamentally important for understanding how regulation of vascular tone is tailore

167 Understanding how regulatory sequences interact in the c

168 Understanding how reproductive isolation varies across p

169 Understanding how reward-based decision making is affect

170 d with preclinical AD.SIGNIFICANCE STATEMENT Understanding how risk factors for Alzheimer's disease (

171 Understanding how RNA secondary structure prediction met

172 Understanding how rock-forming minerals transform under

173 Understanding how roots develop and how they can be bioe

174 Understanding how ROS are linked to blebbishield-mediate

175 to study the RQC and provide a framework for understanding how RQC factors coordinate their activitie

176 Understanding how salt bridges promote their stability i

177 This study will be useful in understanding how SC metabolism contributes to PNS funct

178 Understanding how scientists' social embeddedness shapes

179 Understanding how seeds obtain and store nutrients is ke

180 Understanding how selection acts on risk preference is c

181 Our work presents a general framework for understanding how selection acts upon a pathogen that co

182 Understanding how selective pressure from chemotherapy d

183 Our findings are relevant for understanding how sequence-encoded information in disord

184 A fundamental problem in neuroscience is understanding how sequences of action potentials ("spike

185 Thus, understanding how sex impacts immunity requires the eluc

186 Understanding how signaling pathways and cytoskeletal pr

187 A, our work has wide-ranging implications in understanding how small molecules can interact with spec

188 Understanding how small molecules interact with DNA is e

189 Despite growing interest in understanding how social factors drive poor health outco

190 e behavioral response.SIGNIFICANCE STATEMENT Understanding how social factors influence nervous syste

191 Understanding how sodium pumps contribute to network reg

192 ese microbial 'bioindicators' are useful for understanding how soil microbial communities respond to

193 cysteine fatty (S-fatty) acylated proteins, understanding how specific sites and quantitative levels

194 PRAS40 as a linker protein paves the way for understanding how stress regulates exosome secretion und

195 gnaling mechanism may have a major impact on understanding how stress response via GC signaling regul

196 Understanding how stromal signals regulate the developme

197 Understanding how structural and dynamic disorder impact

198 ity to model global carbon fluxes depends on understanding how terrestrial carbon stocks respond to v

199 Understanding how the brain accommodates multiple langua

200 Understanding how the brain controls ovulation is critic

201 Perspective, we evaluate current progress in understanding how the brain encodes our sense of directi

202 Understanding how the brain extracts depth from two diff

203 imination and ranging.SIGNIFICANCE STATEMENT Understanding how the brain makes sense of the multitude

204 ying intrinsic cortical computations and for understanding how the brain regulates competing inputs.

205 ng alcoholics will relapse at least once and understanding how the brain regulates relapse will be ke

206 of this study have pivotal implications for understanding how the circadian clock modulates sleep an

207 offers an empirically testable framework for understanding how the cortex accomplishes inference, exp

208 Understanding how the differences in response to these t

209 Further, understanding how the different dimensions relate to one

210 Understanding how the Ebola virus surface glycoprotein f

211 Understanding how the El Nino-Southern Oscillation (ENSO

212 t opportunities for discovering materials or understanding how the final products form.

213 ing the basis of such motor control requires understanding how the firing of different types of dopam

214 expression and regulation is fundamental to understanding how the genome functions.

215 cute window after trauma may hold the key to understanding how the genomic storm is initiated and may

216 cription of the past decade of research into understanding how the geometry and size of nanoparticles

217 Our results are a major step towards understanding how the global architecture of the renal v

218 Understanding how the hippocampus switches between diffe

219 a hallmark of Ebola virus disease.IMPORTANCE Understanding how the host responds to viral infections

220 Understanding how the human visual system develops is cr

221 Understanding how the increasing variety of identified u

222 composition of the constituent 2D layers and understanding how the interactions between layers drive

223 Understanding how the magnetic fields affect the formati

224 Recent advances in understanding how the mammalian immune system and intest

225 mations in vivo and also provide a basis for understanding how the misfolded protein structure impact

226 Understanding how the nervous system resolves such ambig

227 Therefore, understanding how the nervous system shapes the immune r

228 binding, we provide an initial step towards understanding how the neuron-astrocyte pair senses and r

229 ct principal cells is a critical step toward understanding how the OB operates.

230 To expand the theoretical basis for understanding how the oligomeric state of a transcriptio

231 These results move us towards understanding how the PAG might be intricately involved

232 Understanding how the paradox biases local observations

233 Understanding how the peripheral nervous system responds

234 This study focuses on understanding how the post-translational phosphorylation

235 Yet answering this question is key to understanding how the spindle generates and responds to

236 Understanding how the structure of cognition arises from

237 Understanding how the temperature-mortality association

238 constitutes an initial important step toward understanding how the tubulin code is written through th

239 As such, understanding how the two main sodium transport proteins

240 th their cargo is of critical importance for understanding how the unique ciliary domain is establish

241 Understanding how the unique genetic makeup and structur

242 individuals, underscoring the importance of understanding how the virus counteracts host defense mec

243 structing the lineage of cells is central to understanding how the wide diversity of cell types devel

244 ns from those in other cell types as well as understanding how their functions change over time.

245 Understanding how these cells are regulated and what the

246 Understanding how these cellular and network phenomena i

247 gating and provide essential constraints for understanding how these channels can be tuned by diverse

248 y are tethered within the MOF is critical to understanding how these components couple to govern the

249 Understanding how these different characteristics are in

250 Understanding how these distinct mechanisms interact dur

251 allenging, there is considerable interest in understanding how these enzymes carry out this difficult

252 Key to understanding how these factors combine to shape develop

253 Understanding how these factors condition access to, and

254 Not understanding how these materials assemble at atomic sca

255 Understanding how these mutations impact on ER function

256 le copies of ~30 different nucleoporins, and understanding how these nucleoporins assemble into the N

257 mucosal surfaces, and interest is growing in understanding how these organisms may contribute to heal

258 Understanding how these organisms respond to environment

259 ill this role by acting as chemosensors, but understanding how these rare and unique cell types trans

260 Understanding how these regions interact is a fundamenta

261 Understanding how these sequence modifications lead to t

262 re a crucial component of WNV pathology, and understanding how they are regulated is important for ta

263 l association between proteins is crucial to understanding how they function in biological systems.

264 ce of these opposing neural connections, and understanding how this balance is achieved relies on kno

265 family HECT E3s and suggest a framework for understanding how this family of E3s generates Ub signal

266 ovel findings not only have implications for understanding how this important class of foraging decis

267 of Mycobacterium tuberculosis infection, and understanding how this is regulated is important for the

268 Towards understanding how this residue impacts the L-glutaminase

269 a apoptosome association will be helpful for understanding how to control apoptosis using either natu

270 stereoretentive metathesis with the goal of understanding how to design a new class of E-selective m

271 Understanding how to design cell permeable ligands for i

272 essing potential chemical risk; furthermore, understanding how to generate a relevant hepatocyte will

273 designs in nonhuman primates is critical for understanding how to improve upon immunogen design to in

274 Understanding how to increase immune infiltration of gli

275 However, understanding how to manipulate anisotropic elemental di

276 Understanding how to mitigate language barriers is becom

277 ulations and with important implications for understanding how to optimize vaccine responses or limit

278 rase holoenzyme has provided a framework for understanding how TR, TERT, and other proteins from cili

279 omes in the genome is thus essential towards understanding how transcription is regulated.

280 rp39, supports yeast U1 snRNP as a model for understanding how transiently associated auxiliary prote

281 basic learning theory offer a framework for understanding how traumatic events can lead to a range o

282 Our study is an important step toward understanding how tubulin isoform composition tunes micr

283 Thus, understanding how tumor and stromal cells respond to hyp

284 Understanding how tumor cells escape from immune attack

285 lenges that are currently under study toward understanding how ubiquitin governs cell cycle regulatio

286 Unleashing such potential, however, requires understanding how urban parameters affect the fraction o

287 Understanding how V1 local processing relates to downstr

288 Ultimately, understanding how various ubiquitin interacting proteins

289 Understanding how ventral neuroepithelial progenitors di

290 Understanding how viruses adapt to new environments and

291 Thus, understanding how viruses evade or exploit macrophage fu

292 These results have implications for understanding how viruses manipulate the physiology and

293 st that visual fixations are more crucial to understanding how visual search works than are the attri

294 -specific temperature effects is pivotal for understanding how warming affects animal populations and

295 Understanding how water and solutes enter and propagate

296 f regions within the MD cortex is crucial to understanding how we can coordinate and execute complex

297 Understanding how well models identify individuals who w

298 Understanding how wild animals, especially those already

299 species specialized for animal pollination, understanding how wild pollinators utilize resources acr

300 These findings are novel in understanding how wound healing is regulated.