ライフサイエンスコーパス: undifferentiated cell

1 ivated than when it was expressed earlier in undifferentiated cells.

2 however, indicating the presence of residual undifferentiated cells.

3 ecting against survival of differentiated or undifferentiated cells.

4 lls: the boundary between differentiated and undifferentiated cells.

5 ed cells compared to its hypermethylation in undifferentiated cells.

6 alance the creation of lineage-committed and undifferentiated cells.

7 localization at cell-cell contact region in undifferentiated cells.

8 age commitment and cause the accumulation of undifferentiated cells.

9 r Sp1 in differentiated cells and for Sp3 in undifferentiated cells.

10 ced within 24 h in vegetative tissues and in undifferentiated cells.

11 e secretory poly(A) site is not expressed in undifferentiated cells.

12 ly in TPA-differentiated HL-60 cells than in undifferentiated cells.

13 and maintenance of the viral copy number in undifferentiated cells.

14 cycle and proliferate to generate a mass of undifferentiated cells.

15 ) site and inhibits poly(A) tail addition in undifferentiated cells.

16 ncreases in the frequency of morphologically undifferentiated cells.

17 its GTP loading returned to a level found in undifferentiated cells.

18 fficient to activate late gene expression in undifferentiated cells.

19 wer or similar in differentiated compared to undifferentiated cells.

20 in differentiated keratinocytes compared to undifferentiated cells.

21 ng in heterogeneous populations that contain undifferentiated cells.

22 ter and negatively regulates its activity in undifferentiated cells.

23 e masses supported by a column of apparently undifferentiated cells.

24 vation without abolishing Xist expression in undifferentiated cells.

25 ives rise to the unstable Xist transcript in undifferentiated cells.

26 vels of read-through into the late region in undifferentiated cells.

27 rogeneous series of polyadenylation sites in undifferentiated cells.

28 he developmental fate of a broad spectrum of undifferentiated cells.

29 ntiated cells were 17 mV more polarized than undifferentiated cells.

30 chaperone complex predominantly expressed in undifferentiated cells.

31 d cells metabolized 2-fold more ROL than did undifferentiated cells.

32 the CLAVATA1 (CLV1) locus accumulate excess undifferentiated cells.

33 e detectable in similar amounts within these undifferentiated cells.

34 ing that sdk is necessary in the surrounding undifferentiated cells.

35 fold in PMA-differentiated cells compared to undifferentiated cells.

36 sis has been compared for differentiated and undifferentiated cells.

37 howed a membrane staining pattern typical of undifferentiated cells.

38 were blocked by Joro spider toxin (JSTx) in undifferentiated cells.

39 xternal Ca2+ (2 mM) was 292% greater than in undifferentiated cells.

40 ed the miRNA signature of differentiated and undifferentiated cells.

41 iciently processed in differentiated than in undifferentiated cells.

42 ted human airway epithelial cells but not in undifferentiated cells.

43 s in significant increases in cell growth of undifferentiated cells.

44 d hiPSCs), is teratoma formation by residual undifferentiated cells.

45 he regulator of vesicular sorting ESCRT-0 in undifferentiated cells.

46 fe in differentiated MEL cells compared with undifferentiated cells.

47 pical death of identifiable neurons, glia or undifferentiated cells.

48 differentiated Caco2-BBE cells compared with undifferentiated cells.

49 on of molecular asymmetries across fields of undifferentiated cells.

50 In undifferentiated cells, a 2day exposure to the OPs had n

51 he patterns of PECAM expression suggest that undifferentiated cells, a prevascular cell type, and vas

52 ely express Id-2 retained characteristics of undifferentiated cells: (alpha)1 integrin expression was

53 erentiated 3T3-L1 cells but had no effect in undifferentiated cells, although ET-1 stimulated phospha

54 tly or indirectly regulated by GRHL2 in both undifferentiated cells and air-liquid interface cultures

55 24 reduced both the levels of HPV genomes in undifferentiated cells and amplification upon differenti

56 d1/5/8 activation via ALK2/3/6 is blocked in undifferentiated cells and becomes activated upon differ

57 nuous organogenesis by maintaining a pool of undifferentiated cells and directing descendant cells to

58 aling is required to maintain a reservoir of undifferentiated cells and ensure continuity of adult hi

59 hitectural factors expressed in embryonic or undifferentiated cells and highly associated with transf

60 is known about how chromosomes are packed in undifferentiated cells and how nuclear organization chan

61 ncreased the HSP70 staining intensity in the undifferentiated cells and less so in the differentiated

62 immunoreactivity is uniformly distributed in undifferentiated cells and located at the inner surface

63 ts robustly activates expression of Pparg in undifferentiated cells and permits cells to undergo adip

64 87.5%) were stably inherited both within the undifferentiated cells and post-differentiation.

65 y protein DNMT3L, which is only expressed in undifferentiated cells and recruits DNMT3A to initiate D

66 esent in adult marrow, that can replicate as undifferentiated cells and that have the potential to di

67 t P(0) is dispensable for Xist expression in undifferentiated cells and that P(1) can be used in both

68 Transduction efficiency was high in undifferentiated cells and was enhanced in well-differen

69 egion devoted to a slow rate of growth among undifferentiated cells, and an anterior region in which

70 chief cells, increased numbers of mucous and undifferentiated cells, and an increase in the number of

71 ion patterns, its promoter is most active in undifferentiated cells, and depletion of HIPSTR in HEK29

72 roliferation, upregulation of the numbers of undifferentiated cells, and extended lag phase.

73 essor that regulates the epigenetic state of undifferentiated cells, and showed that Plzf is coexpres

74 LIN28 expression was high in undifferentiated cells, and was downregulated rapidly up

75 l cardiac differentiation, avoid introducing undifferentiated cells, and will likely require immune m

76 Decapentaplegic (Dpp), acts at long range on undifferentiated cells anterior to the furrow, causing t

77 Undifferentiated cells are eliminated in the first two p

78 stem cells (MSCs).New vascular networks from undifferentiated cells are essential for repair/regenera

79 From these experiments it appears that undifferentiated cells are more sensitive to the oncogen

80 Recent studies have demonstrated that these undifferentiated cells are multipotent stem cells, sugge

81 tured epidermal cell sheets (CES) containing undifferentiated cells are useful for treating skin burn

82 hesis in a concentration-dependent manner in undifferentiated cells at both preconfluent and confluen

83 erior progression, driven by a population of undifferentiated cells at the posterior-most end of the

84 CLV2 and CLV3) result in the accumulation of undifferentiated cells at the shoot and floral meristems

85 hematopoietic stem cells (HSCs) are the most undifferentiated cells at the top of the hematopoietic h

86 characterized by sequential proliferation of undifferentiated cells, basal body production, Foxj1 exp

87 We sought to determine whether undifferentiated cells block the trafficking of tegument

88 t protein (CDP), a factor which is active in undifferentiated cells but inactive in terminally differ

89 es to negatively regulate gene expression in undifferentiated cells but not in differentiated cells.

90 its metabolites accumulated in the Golgi in undifferentiated cells but targeted to unique vesicular

91 ntiation, CHF1 mRNA was barely detectable in undifferentiated cells but was induced highly in differe

92 endogenous SMC marker genes in chromatin in undifferentiated cells, but it did in differentiated A40

93 ly, we have reconstituted functional GSVs in undifferentiated cells by double transfection of Glut4 a

94 flow at low, nontoxic concentrations through undifferentiated cells by providing buffering storage fo

95 erated structures are formed from a mound of undifferentiated cells called a blastema, found just bel

96 ganisms depends on the activity of groups of undifferentiated cells called stem cells.

97 of homeotic genes, originate from a group of undifferentiated cells called the floral meristem.

98 sful feeder-free hES culture system in which undifferentiated cells can be maintained for at least 13

99 ormed teratomas more efficiently, from which undifferentiated cells can be recovered.

100 Thus, Xist expression in undifferentiated cells can be separated genetically from

101 esized that PBGs are populated by mature and undifferentiated cells capable of proliferation in patho

102 oral structural fluctuations of chromatin in undifferentiated cells characterize the stem cell state.

103 fficulties in deriving endodermal cells from undifferentiated cell cultures, applications using lung

104 of adult stem cells focus on the relatively undifferentiated cells dedicated to the renewal of rapid

105 dies have shown that differentiated, but not undifferentiated, cells develop prolonged SINV replicati

106 ation was enhanced 5-fold by DEX, whereas in undifferentiated cells, DEX enhanced replication approxi

107 type I, BSP, and osteocalcin indicated that undifferentiated cells did not express BSP or osteocalci

108 d cells robustly expressed Le(x), relatively undifferentiated cells did not, and the expression level

109 Undifferentiated cells displayed a short lifetime indica

110 ewly induced Th2 population was derived from undifferentiated cells distinct from the Th1 cells prese

111 Forced expression of sortilin in undifferentiated cells does not recruit IRAP into the ve

112 thought to contribute to stable silencing in undifferentiated cells due to its enrichment on the inac

113 blocks the expression of let-7 microRNAs in undifferentiated cells during development, and functions

114 cell lines and are abundantly distributed in undifferentiated cells during development.

115 onsecutive generations of differentiated and undifferentiated cells during Th2 polarization in vitro.

116 ental flexibility by (1) eliminating damaged undifferentiated cells early in development and then (2)

117 In undifferentiated cells, ectopic expression of CHE-1 resu

118 (translational and rotational strain) to the undifferentiated cells embedded in a collagen gel.

119 d in pancreatic ductal cells and clusters of undifferentiated cells emerging from the ductal epitheli

120 Undifferentiated cells expressing little ACE2 were poorl

121 A hyperplastic pancreas consisting of undifferentiated cells expressing Pdx1, Nkx6.1, and cell

122 Y chromosome can be used to detect migrated undifferentiated cells expressing stem-cell antigens and

123 ed in repair between SY5Y differentiated and undifferentiated cell extracts.

124 global gene expression profiling showed that undifferentiated cells fell into two clusters delineated

125 tic differentiation and permits expansion of undifferentiated cells, findings consistent with the kno

126 genitors, remaining phenotypically stable as undifferentiated cells for months with a cell division i

127 ndant in cauliflower meristematic tissue and undifferentiated cells from Arabidopsis, soybean, and ca

128 the N pathway to prevent a subpopulation of undifferentiated cells from choosing a neuronal fate.

129 ic oral ectoderm is specifically retained in undifferentiated cells from the pars intermedia of the a

130 ization of p50 was seen in areas where basal undifferentiated cells give rise to differentiated cell

131 TX, where MTX is methotrexate) compared with undifferentiated cells (HT-29/p), whereas no differentia

132 In undifferentiated cells, hypersensitive regions exist in

133 c differentiation and permitted expansion of undifferentiated cells in 32D myeloid progenitors.

134 This model holds that undifferentiated cells in a zone of fixed size at the di

135 The MLS-2 protein is present in nuclei of undifferentiated cells in the early M lineage and in a s

136 show that CD44 labels a population of small, undifferentiated cells in the gastric unit isthmus where

137 To maintain a steady pool of undifferentiated cells in the SAM while continuously gen

138 ained mitotic activity to maintain a pool of undifferentiated cells in the SAM.

139 Isl1, a transcription factor associated with undifferentiated cells in the secondary heart field in o

140 ons: c1v1 and Clv3 mutants accumulate excess undifferentiated cells in the shoot and floral meristem,

141 so required for the continued maintenance of undifferentiated cells in the shoot meristem and for pro

142 Metaplasia of undifferentiated cells in the terminal airways was also

143 ls that exhibit characteristics of primitive undifferentiated cells, including a high nucleus/cytopla

144 the blockade of PI3K activity in human fetal undifferentiated cells induced morphological and functio

145 that were transcriptionally either active in undifferentiated cells, induced during differentiation,

146 ye imaginal disc and transforms thousands of undifferentiated cells into a precisely ordered repetiti

147 nd eye is formed by selective recruitment of undifferentiated cells into clusters called ommatidia du

148 ion might transform an initial population of undifferentiated cells into more regular populations of

149 This was due to an increased recruitment of undifferentiated cells into striated muscle, rather than

150 primary buds, that harbor a small number of undifferentiated cells, into mature zooids containing fu

151 cells from a group of seemingly equivalent, undifferentiated cells is a central paradigm of developm

152 suggesting that the block to replication in undifferentiated cells is at the step of viral entry.

153 se regulation of Bar expression in the basal undifferentiated cells is crucial for neural patterning

154 High expression of these genes in undifferentiated cells is maintained by activation of th

155 ow evidence that Bar expression in the basal undifferentiated cells is regulated by at least three di

156 progenitor cell population as a reservoir of undifferentiated cells is required for organ development

157 fferentiate from among a field of equipotent undifferentiated cells is the process of R8 photorecepto

158 lium from the skin and the presence of trace undifferentiated cells left in the dermis.

159 The undifferentiated cell line SW480 and undifferentiated Ca

160 nduce cell apoptosis in a mitotic competent, undifferentiated cell line, PC-12.

161 Undifferentiated cell lines developed that exhibited dia

162 pression was found to be highest in the most undifferentiated cell lines, and this was related with a

163 In undifferentiated cells, LIPs act as dominant-negative re

164 oping photoreceptors located posteriorly and undifferentiated cells located anteriorly.

165 Cell division was stimulated fourfold in undifferentiated cells located in the proliferative comp

166 Thus, in undifferentiated cells, loricrin expression is suppresse

167 , large interior cell patches expressing the undifferentiated cell marker LHX9, and a loss of differe

168 Slow catecholamine secretion in undifferentiated cells may be caused in part by a lack o

169 t that EBV(+) cancers usually contain mostly undifferentiated cells may be due in part to these cells

170 However, recent studies show that undifferentiated cells may shape their environment throu

171 Stat3, Raf1, MEK, and ERK), proliferation of undifferentiated cells (MEK and ERK), and proliferation

172 In addition to its ability to eliminate undifferentiated cells, miR-302a switch also holds great

173 As a result, tumor-like growths of undifferentiated cells (neoplasms) develop beneath the e

174 Undifferentiated cell nuclei are easily deformable, with

175 n of cells expressing markers for stem cells/undifferentiated cells (Oct4, SSEA4), neurons (Neurofila

176 molecular similarities between neoblasts and undifferentiated cells of other organisms raise the poss

177 er restrict gene expression to predominantly undifferentiated cells of the M lineage.

178 istence by establishing latent infections in undifferentiated cells of the myeloid lineage, such as C

179 , are associated with the NE specifically in undifferentiated cells of the root tip.

180 meristem, while stm mutants fail to form the undifferentiated cells of the shoot meristem during embr

181 ter of the meristem divide slowly and remain undifferentiated, cells on the meristem periphery divide

182 differentiated vertebrate cells, but not in undifferentiated cells or cancer cells.

183 educing the numbers of colonies derived from undifferentiated cells or hematopoietic precursor cells.

184 ells either reacquire epigenetic features of undifferentiated cells or maintain an epigenetic signatu

185 Moreover, the results suggest that undifferentiated cells outside the facet continue to inf

186 A2B5(+) cells, maintained as undifferentiated cells over multiple passages, can subse

187 lity of transcriptionally inactive genes: In undifferentiated cells, PBX1 is bound to the H1-compacte

188 rphology observations supported retention of undifferentiated cell phenotype at 12 degrees C, transit

189 y human oral keratinocytes as a small-sized, undifferentiated cell population capable of retaining th

190 Hh activity also induced the expansion of an undifferentiated cell population expressing progenitor m

191 We identified a rare undifferentiated cell population that is intermingled wi

192 When Sens is expressed in undifferentiated cells posterior to the morphogenetic fu

193 FZD7 expression is significantly elevated in undifferentiated cells relative to differentiated cell p

194 Neoblasts, originally defined as undifferentiated cells residing in the adult parenchyma,

195 embryos of an interspecific cross, in which undifferentiated cells show biallelic expression and acq

196 o differentiate through serum starvation and undifferentiated cells show differing distributions of b

197 Overexpression of ezrin in undifferentiated cells showed a Triton-insoluble ezrin c

198 Proliferating/undifferentiated cells showed higher C16:0 (1.7-fold) an

199 over in vivo requires genetic tagging of the undifferentiated cells so that the clonal marker of indi

200 ANCR lncRNA is thus required to enforce the undifferentiated cell state within epidermis.

201 progenitor differentiation and maintain the undifferentiated cell state.

202 activity during neurogenesis to maintain the undifferentiated cell state.

203 umber of photoreceptors in a facet to eight, undifferentiated cells surrounding assembling facets sen

204 In undifferentiated cells, SV induced a rapid shutdown of c

205 cayed at similar rates in differentiated and undifferentiated cells (t(12) approximately 4.6 days), b

206 a property of pluripotent cells, but not of undifferentiated cells that are already lineage committe

207 es a cardiac stem cell pool characterized by undifferentiated cells that are self-renewing, clonogeni

208 In root tips, relatively undifferentiated cells that contain vacuoles labeled sep

209 cell niches, maintain a pool of multipotent, undifferentiated cells that divide and differentiate to

210 t apical meristem (SAM) comprises a group of undifferentiated cells that divide to maintain the plant

211 Embryonic stem (ES) cells are pluripotent-undifferentiated cells that have a great interest for th

212 lge in the human follicle is a collection of undifferentiated cells that is prominent only in the fet

213 T3-dependent proliferation of phenotypically undifferentiated cells that nevertheless functioned as c

214 nts are accomplished by meristems, groups of undifferentiated cells that persist as stem cells and in

215 In undifferentiated cells the enhancer activity is represse

216 6H1) expression is restricted to flowers and undifferentiated cells, the CYP71D351 (T16H2) expression

217 iomyogenesis, including the specification of undifferentiated cells, the establishment of heart patte

218 We found that, in undifferentiated cells, the TGFbeta/activin/nodal branch

219 Each undifferentiated cell then acquired either primary or se

220 rated through the rearrangement of a pool of undifferentiated cells, there is nonetheless proliferati

221 ate gland has proceeded from a solid mass of undifferentiated cells to a stage in which differentiate

222 ance incoming FT signals, allowing a pool of undifferentiated cells to be maintained despite strong d

223 ignaling is blocked, Hh signaling can induce undifferentiated cells to become pre-proneural but does

224 type specification relies on the capacity of undifferentiated cells to properly respond to specific d

225 In undifferentiated cells, total beta-catenin protein conte

226 programming factors (POU and HB4), directing undifferentiated cells toward neural fate in vivo.

227 In comparison to undifferentiated cells, twice the amount of bound STb (a

228 f specific signaling pathways operational in undifferentiated cell types.

229 LP67A in the localization of mitochondria in undifferentiated cell types.

230 This suggests that in undifferentiated cells vesicle transport from the Golgi

231 ic proteins, we show that in contrast to the undifferentiated cells, Vpr did not down-regulate the ex

232 While Bin1 in undifferentiated cells was localized exclusively in the

233 19 neuronal cells, and to a lesser extent in undifferentiated cells was observed.

234 the "lysosomal/mitochondrial" fraction from undifferentiated cells was responsible for the modificat

235 Sortilin ectopically expressed in undifferentiated cells was translocated to the plasma me

236 wed that alpha6B, which is characteristic of undifferentiated cells, was expressed by the lens epithe

237 The undifferentiated cells were characterized by high scores

238 Undifferentiated cells were negative for markers of bone

239 Initial undifferentiated cells were positioned randomly, subject

240 DNMT1 protein was found enriched in undifferentiated cells, where it was required to retain

241 transcript lacking exon 9 was predominant in undifferentiated cells, whereas a transcript bearing exo

242 campal progenitors, nicotine is cytotoxic to undifferentiated cells, whereas it spares the same cells

243 factor (PCAF) complex to the TR2 promoter in undifferentiated cells, whereas it triggers recruitment

244 Binding is not detected in undifferentiated cells which express Id3 but peaks durin

245 subventricular zone (SVZ) contains a pool of undifferentiated cells, which proliferate and migrate al

246 Furthermore transfection of undifferentiated cells with calbindin results in dramati

247 from LL and TZ cultured in DMEM give rise to undifferentiated cells with high growth capacity, and he

248 t stem cells represent unique populations of undifferentiated cells with self-renewal capacity.

249 ond class ('stable') were pre-established in undifferentiated cells, with enhancers constitutively ma

250 n plants depends on the continuous supply of undifferentiated cells within meristems.