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5 he development of the Xpert MTB/RIF assay is undoubtedly a landmark event, clinical and programmatic
10 8 mutants but retrograde IFT is absent; this undoubtedly accounts for the accumulation of rafts in th
11 regulate granule cell neurogenesis and these undoubtedly act in concert with opioids to shape develop
13 Genetic manipulations of these genes will undoubtedly add to the emerging genetic hierarchy regula
15 on degeneration into diagnostic criteria has undoubtedly advanced diagnosis, but even earlier diagnos
18 al changes occurring during pain states will undoubtedly aid in the discovery of effective pain pharm
20 zing this newly identified bovine CD5L, will undoubtedly aid in understanding the role that the CD5-C
21 , new antiviral drugs, and new vaccines will undoubtedly alter our approaches to influenza control an
23 shielding from loosely associated metals is undoubtedly an important influence during this metal-med
24 ishing characteristic of the RNA/DNA hybrid, undoubtedly an important structural feature conferring s
27 unanswered and new compelling questions will undoubtedly arise, the relative maturity of this field p
30 ellular differentiation and apoptosis, would undoubtedly assist their clinical development as antican
31 Mutations in mitochondrial DNA (mtDNA) are undoubtedly associated with a diverse spectrum of human
33 process has been modified over time and will undoubtedly be altered in the future to improve the proc
36 tigens using T cells from immune donors will undoubtedly be critical for the development of vaccines
38 olution structures or model structures could undoubtedly be improved in accuracy by the incorporation
39 positions besides these diamagnetic ions can undoubtedly be made using a similar approach, which cons
40 ltimately successful vaccine strategies will undoubtedly be multifactorial, incorporating multiple an
41 s, airborne remote sensing technologies will undoubtedly be of major importance in optimized manageme
44 sential when, as was true with SARS and will undoubtedly be the case with future epidemics, scientifi
45 ir respective receptors within the skin will undoubtedly be the focus of future drug development for
48 and the experiment platform established will undoubtedly become a new paradigm for future research an
50 Finally, although blood pressure lowering is undoubtedly beneficial, the concepts of single risk fact
52 nd the generation of epileptic seizures will undoubtedly benefit from research utilizing these connec
53 ing has resulted in new classifications that undoubtedly benefit patients and clinicians in their end
54 The ability to survive in diverse tissues is undoubtedly benefited by sensory pathways that recognize
57 is of fundamental importance, and this will undoubtedly broaden the scope of research on the chemist
58 ting genetic disease and safer methods would undoubtedly broaden the variety of possible illness that
60 ver, whereas amphetamine and methamphetamine undoubtedly cause irreversible brain damage with long-te
61 Although metabolic syndrome in adulthood is undoubtedly caused by multiple factors, including modifi
64 of the evolution of the malaria genome will undoubtedly clarify the current controversy, the importa
69 lature, which painstakingly accounts for the undoubtedly complex and manifold role of gap junctions i
70 ity to systemic lupus erythematosus (SLE) is undoubtedly complex and, presumably, involves multiple l
75 scrutiny of velo-cardio-facial syndrome will undoubtedly continue for many years to come with the hop
76 ed many new concepts and therapies that will undoubtedly continue to be rapidly applied to the other
77 d to many existing antiviral agents and will undoubtedly continue to be the basis of future drug desi
78 matic overviews underscore that imaging will undoubtedly continue to dramatically shape the future of
79 known and newly emerging pathogens will also undoubtedly continue to enhance our understanding of the
83 ly understood, although genetic determinants undoubtedly contribute in substantial ways to the outcom
84 anding the functions of mosquito miRNAs will undoubtedly contribute to a better understanding of mosq
86 aracteristic of systemic lupus erythematosus undoubtedly contribute to the accelerated vascular disea
87 tion and multiple comorbid conditions, which undoubtedly contribute to their enhanced susceptibility
88 in which we practice, genetic variation will undoubtedly contribute to variability in therapeutic res
90 ineages in the marrow of colitis mice, which undoubtedly contributed to the anemia observed in these
91 facility pervasive in everyday life that has undoubtedly contributed to the success of our species.
92 esent in a diverse population of neurons and undoubtedly contributes to numerous functions in additio
94 atty acids; thus, LDL fatty acid composition undoubtedly contributes to the process of LDL oxidation.
95 ugh the intrinsic virulence of P. aeruginosa undoubtedly contributes to this phenomenon, it is unclea
97 PimA experiences remarkable flexibility that undoubtedly corresponds to the N-terminal "Rossmann fold
98 tween genetic and environmental factors will undoubtedly create new opportunities for public health a
100 hown that although the oligomeric chains are undoubtedly discrete and monodisperse, they nevertheless
101 chanism of protein complex dissociation will undoubtedly drive the technology into new areas of enhan
102 for this myopathy are evolving, function is undoubtedly driven by sequence variations and post-trans
103 number of different evolutionary niches has undoubtedly driven the high degree of phenotypic and gen
104 sympathectomy have been employed sparingly, undoubtedly due to potentially hazardous soft tissue con
108 The utility of the spiropyran switch will undoubtedly endow these materials with far-reaching appl
112 tributable, in part, to the scene chaos that undoubtedly exists, poor triage and missed diagnosis of
113 uture research on these new discoveries will undoubtedly expand our understanding of the role of EPCR
114 uture advances in technology and safety will undoubtedly expand the HIFU role in this indication as m
116 hment of an authentic mouse model of DN will undoubtedly facilitate testing of translational diagnost
119 mulations that microfluidic technologies can undoubtedly fine-tune reaction times and reagents concen
121 juvant design and oral vaccine delivery will undoubtedly foster the development of effective fish vac
122 be fertile grounds for discoveries that will undoubtedly further broaden our understanding of the cat
126 rganisms to produce antibiotic resistance is undoubtedly going to outstrip availability of new antibi
128 on within the framework of thin plate theory undoubtedly has a higher accuracy and broader scope than
129 CVD outcomes; the policies we explored would undoubtedly have additional beneficial effects upon othe
131 ri-, and posttransplantation clinical events undoubtedly have an impact on posttransplantation immune
132 te superior than their rival materials, will undoubtedly have an important impact within the near fut
133 nesis of this larval kidney form, which will undoubtedly have applicability to higher vertebrate kidn
136 e that all XGG and XAG (X = C or T) duplexes undoubtedly have structures similar to those of the 16-m
138 our understanding of these systems and will undoubtedly impact development of future information tec
139 ized mercury (GOM) measurement uncertainties undoubtedly impact the understanding of mercury biogeoch
140 While siderophore-mediated Fe(III) uptake is undoubtedly important at early stages of infection, thes
141 gh a distinct, stable secondary structure is undoubtedly important in most noncoding RNAs, the stabil
142 nomic factors and therapeutic compliance are undoubtedly important issues in long-term allograft surv
143 pact of complex genetic interactions, though undoubtedly important, has received little investigation
144 d intron presence/absence polymorphisms will undoubtedly improve our understanding of the evolution o
145 from gene expression profiling studies will undoubtedly improve the prediction of treatment response
147 ization of each medulloblastoma subtype will undoubtedly improve treatment of this disease and provid
149 f these assays to forensic laboratories will undoubtedly increase the sensitivity and specificity of
153 hape behavior, and emotion regulation - that undoubtedly influence important social and personal outc
154 t interspersed elements (SINEs) in mice that undoubtedly influence many developmental and homeostatic
156 eless, both B and T lymphocyte responses are undoubtedly influenced by Notch ligation, and defining t
159 d array-based DNA sequencing technology will undoubtedly involve research and diagnostic analyses of
160 sis remain to be elucidated, the placenta is undoubtedly involved, as termination of pregnancy eradic
161 ut during infection is poorly understood but undoubtedly involves protein components within the surfa
162 ying regulation remains largely obscure, but undoubtedly involves steps after transcription initiatio
166 , and continued research in these areas will undoubtedly lead to better outcomes for transplant recip
167 e and continued research in these areas will undoubtedly lead to better outcomes for transplant recip
170 tion of these abnormalities as prerenal will undoubtedly lead to incorrect management decisions.
171 collaborative work between these worlds will undoubtedly lead to major discoveries and advances in cl
173 Scientific advances in these areas will undoubtedly lead to the development of more effective th
174 ch for TBPVs and that this kind of work will undoubtedly lead to the discovery of additional novel ti
175 ous uncharacterized T6SS effectors that will undoubtedly lead to the discovery of new biological mech
178 f de novo synthesis, an evolutionary outcome undoubtedly linked to obligatory growth in this metaboli
179 y (MS/MS) on protein-based therapeutics will undoubtedly make it a very valuable addition to the expe
181 d expression of p53, Rb, and Jun, as well as undoubtedly many other proteins may be a result of genom
187 nephropathy (DN), a major cause of ESRD, is undoubtedly multifactorial and is caused by environmenta
190 d-coil structure with inherent plasticity is undoubtedly necessary to accommodate the dynamics of vir
192 mulation through these receptors, which must undoubtedly occur in vivo during antiviral immune respon
194 identify multiple loci with small effects is undoubtedly one of the primary reasons for this problem.
195 at while the function of LKB1 and STRADalpha undoubtedly overlap, they may also have mutually exclusi
200 ng on action choice and rewards received and undoubtedly play a pivotal role in maintaining and adapt
201 helical bundling in alpha- and beta-spectrin undoubtedly play a significant role in tetramerization,
202 ionary changes in transcriptional regulation undoubtedly play an important role in creating morpholog
203 s have revealed that, while gonadal hormones undoubtedly play an important role in sexual differentia
204 h factor for human mast cells, other factors undoubtedly play important roles in the development, sur
205 Although chromatin assembly and modification undoubtedly play major roles in the regulation of HSV-1
208 roperty for a replication initiation protein undoubtedly plays an important role in extending the hos
211 metrics, along with improved therapies, will undoubtedly present both familiar and new challenges in
212 gs of these complement-deficient mice, which undoubtedly prevented efficient gas exchange, causing de
213 ctions with Brca2 and Xrcc3, properties that undoubtedly promote its DNA repair capability in the cel
215 nd 5c and the other benztropine analogs will undoubtedly prove useful in the elucidation of the role
216 nsal E. coli isolate, E. coli HS, which will undoubtedly provide a new baseline from which workers ca
217 information learned from this accident will undoubtedly provide a synthesis of what has or has not b
218 ; however, investigation of this region will undoubtedly provide insight into the functional mechanis
219 rse genetic approach in the axolotl and will undoubtedly provide invaluable insight into the mechanis
220 Foreseeable, this sensor made on this basis undoubtedly provide the most effective and sensitive det
221 peer support elicited through the group FANC undoubtedly provided patients with additional tools to i
222 he basic virology of vector development will undoubtedly reap great rewards over the next decade in t
224 G-1 in membranelike environments, properties undoubtedly related to its antimicrobial and cytotoxic e
226 to optically tunable helical superstructures undoubtedly represent a striking example, owing to their
228 hough the aziridine residue of azinomycin is undoubtedly required for cross-link formation, analogues
230 ly promiscuous and regulatory mechanisms are undoubtedly required to ensure selective interactions.
231 aries invade the fibrin clot, a process that undoubtedly requires an interaction of vascular cells wi
233 tumors harbor immunosuppressive activity and undoubtedly restrict the effectiveness of these strategi
234 Further changes in its epidemiology will undoubtedly result from anticipated changes in the diagn
236 derstanding of mechanisms of cell death will undoubtedly result in the discovery of new drugs with po
238 ely, nonadherence to imatinib and other TKIs undoubtedly results in disease progression and treatment
239 tions of NK cell alloreactive functions will undoubtedly reveal additional roles and potential therap
240 nd non-canonical inflammasome complexes will undoubtedly reveal more surprises on their structure and
241 ntigen testing and prostate cancer treatment undoubtedly saves lives, there are growing concerns rega
242 ss cellular suicide if not murder, that will undoubtedly serve as a research base for many laboratori
244 20 m water depth) to the basement topography undoubtedly shaped by subaerial weathering and/or erosio
245 Interestingly, animal and plant LOX, which undoubtedly share a common ancestor, are related in sequ
247 g specificity in the nervous system and will undoubtedly shed light on many neural developmental diso
250 la melanogaster contain fewer genes than the undoubtedly simpler organism Caenorhabditis elegans?
252 otherapy regimens containing ifosfamide will undoubtedly stimulate interest in a new generation of ra
256 NH2-terminal of the essential glutamate, is undoubtedly the analog of the second aspartate of the As
257 n countries and regions of the world, and is undoubtedly the defining public-health crisis of our tim
259 ation became the favoured explanation and is undoubtedly the major factor driving the frequency chang
260 he specimen is relatively undistorted and is undoubtedly the most complete higher primate skull yet f
263 blood pressure reduction, statin therapy is undoubtedly the single most important risk factor interv
276 entral positive and negative feedback loops, undoubtedly to provide a greater flexibility and dynamic
277 of genome sequence and gene expression will undoubtedly transform biological research and spur the d
278 The bactericidal effects of antibiotics are undoubtedly triggered by target-specific interactions, b
279 ge of these viral proteins improves, we will undoubtedly uncover how the multifunctional nature of th
282 iable quantification of protein markers will undoubtedly underpin profound developments in disease su
286 likelihood of transmission via dentistry is undoubtedly very low, this may be amplified considerably
287 nteresting to note how medical records on an undoubtedly very ordinary citizen were recorded in Londo
290 ing the nature of linguistic representations undoubtedly will benefit from multiple types of evidence
292 The need for Epi-Aids of such outbreaks undoubtedly will persist as an integral part of future p
293 hemical performances is enhanced remarkably, undoubtedly, will have an important influence on the mat
295 lying the association of X. nematophila will undoubtedly yield insights into fundamental processes un
296 eterminants that maintain tumor growth, will undoubtedly yield more effective therapies for these can
297 chromatin regulates SMC differentiation will undoubtedly yield valuable insights into both normal dev
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