ライフサイエンスコーパス: unequivocal

1 resistance exercise in aging populations are unequivocal.

2 e data on L2-E and L3-E interactions are not unequivocal.

3 results suggest that the association is not unequivocal.

4 the initial stage of Alzheimer's disease is unequivocal.

5 Although the evidence is not yet unequivocal, a growing body of evidence supports the exi

6 link between mutant TP53 and human cancer is unequivocal, a significant knowledge gap exists in clini

7 In particular, the unequivocal advantage enjoyed by glutamine at residue 50

8 ng the risk of misdiagnosis and the need for unequivocal amyloid typing.

9 The use of qualifier ions supports unequivocal analyte verification.

10 tent and DNA replication, this method allows unequivocal and direct assignment of cell cycle distribu

11 We present unequivocal and model-free experimental proof for the pr

12 roach in the management of kidney tumors are unequivocal and the role of laparoscopy in nephron-spari

13 PFC nanoparticles provide an unequivocal and unique signature for stem/progenitor cel

14 7.4 years), except for three, experienced an unequivocal angioedema of the lips as a positive reactio

15 both animals and humans have not provided an unequivocal answer.

16 resulting OVA-VIB conjugate, a selective and unequivocal antigenic response to the VIB hapten was obs

17 erformed on 20 biopsies (normal kidney, n=4; unequivocal AR, n=5; features of APN, n=11).

18 ad MRI-evident sacroiliitis, and 6 (12%) had unequivocal AS according to the modified New York criter

19 ine 46 in models of disease should allow the unequivocal assessment of whether GAPDH aggregation infl

20 -characterized structural states provide the unequivocal assignment of amide I marker bands in the Ra

21 -coated microspheres is introduced, allowing unequivocal assignment of docking and membrane fusion.

22 during synthesis was designed to facilitate unequivocal assignment of isobaric residues by MALDI-TOF

23 LYP/6-31G* level with COSMO model, permitted unequivocal assignment of its 2R,3S absolute configurati

24 al cross-repressive interactions that ensure unequivocal assignment of neural progenitor identity to

25 acy provided by FTICR MS allow for rapid and unequivocal assignment of relevant peptides and provide

26 Their structures allow unequivocal assignment of the absolute configuration for

27 In the humic acid, this permits unequivocal assignment of the methine resonance near 53

28 etric assessment of this sample supports its unequivocal assignment to H. sapiens.

29 the use of orthogonal methods is needed for unequivocal assignment.

30 eins from their modified forms, facilitating unequivocal assignments.

31 l explosion in new knowledge with reports of unequivocal association to relevant genes appearing almo

32 ra of selectively (13)C-labeled protein show unequivocal attenuation of cross-peaks after membrane bi

33 nt asymmetric total synthesis to provide the unequivocal authentic materials.

34 These fossils represent the only unequivocal basal theropod embryos found to date.

35 ures, independent of the donor, providing an unequivocal basis to distinguish an effect by virus.

36 or vapor deposition on ice grains, exhibited unequivocal bathochromic shifts of 10-15 nm of the absor

37 The published results do not demonstrate an unequivocal benefit for consolidation with high-dose the

38 y/mortality trial) studies together show the unequivocal benefit for CRT therapy and CRT therapy with

39 controversial because evidence demonstrating unequivocal benefit is lacking.

40 on the prevent/delay end points that reflect unequivocal benefit to a patient: prolongation of life o

41 g the development of cardiac hypertrophy has unequivocal benefits on cardiac function and energetics.

42 can Association for Cancer Research makes an unequivocal call to all who are concerned about public h

43 haemoglobin, but no trial results have shown unequivocal cardiovascular risk reduction with glucose l

44 r discrimination between melanoma and benign unequivocal cases as well as between different atypia su

45 direduced states of the two isomers allowing unequivocal characterization of the reduced species by U

46 Here we report the first unequivocal chemical evidence, based on the delta(13)C a

47 h cirrhosis (defined as bridging fibrosis or unequivocal cirrhosis on biopsy).

48 The lack of a precisely-dated, unequivocal climate proxy from northern China, where pre

49 ials in human subjects have not demonstrated unequivocal clinical benefits.

50 ses of old age, but has failed to deliver an unequivocal clinical breakthrough.

51 The gold standard was an unequivocal clinical diagnosis.

52 than 3 years, Gleason score progression, or unequivocal clinical progression.

53 e results suggest that job control is not an unequivocal concept in relation to mortality; decision a

54 d better-designed studies are needed to draw unequivocal conclusions about the effect of statins on c

55 ate sensitivity and specificity in providing unequivocal confirmation of rhEPO and DPO in equine plas

56 tems and in animal models of oxidant injury, unequivocal confirmation of their beneficial effects in

57 ng sucrose, but human studies do not provide unequivocal data of their cariogenicity.

58 However, unequivocal data required to prove that interchromosomal

59 The only unequivocal deficiency outcome is a bleeding syndrome ca

60 may take damage to both sides to produce an unequivocal deficit of central semantic memory.

61 this notion may be considered intuitive, its unequivocal demonstration is still lacking.

62 However, an unequivocal demonstration of "protein-only" infection by

63 These results represent the first unequivocal demonstration of a role for Ldb1 in erythrop

64 search design was not capable of offering an unequivocal demonstration of inequity aversion.

65 some 25 million years and provides the first unequivocal demonstration of ostracods in the Ordovician

66 cal application of this principle depends on unequivocal demonstration of safety in primate models fo

67 ft composition and properties have prevented unequivocal demonstration of their functional relevance.

68 This is an unequivocal demonstration that a terminally differentiat

69 Our work is the first unequivocal demonstration that homologous recombination

70 These studies also represent the first unequivocal demonstration that OxDC activity is uniquely

71 rected toward a polyamine gene and the first unequivocal demonstration that SSAT induction initiates

72 ramide signal amplification (TSA) to achieve unequivocal detection of cell bodies of GABAergic neuron

73 n situ through-container analysis; achieving unequivocal detection of multiple chemical markers known

74 The method enabled the unequivocal detection of up to 1% of each adulterant, al

75 s work describes a methodology for the first unequivocal determination of diphenhydramine bound to en

76 This approach provides unequivocal determination of specific reactions in the p

77 SY, and COSY data obtained have also allowed unequivocal determination of the orientation of the PBD

78 levels, has clinical utility in providing an unequivocal diagnosis in patients and in identifying aff

79 ia motion contrast and may contribute to the unequivocal diagnosis of CNV in this population.

80 Unequivocal direct observations have established that th

81 Unequivocal discrimination between neutral variants and

82 fferent compared to conventional milk but an unequivocal discrimination was not possible either in su

83 ocalization of nanoparticles, does not allow unequivocal distinction between cell surface-bound and i

84 to-noise ratio for nickel porphyrins enables unequivocal elemental composition assignment confirmed b

85 He presented specific, unequivocal emotion recognition impairments.

86 Unequivocal eradication of donor leukocyte microchimeris

87 Using En(a-) cells to get an unequivocal estimate of the use of glycophorin A (GPA) a

88 remain as to their specific role(s), and no unequivocal evidence exists showing that these compounds

89 sights into the nanorod growth mechanism and unequivocal evidence for a concerted growth-organization

90 These findings provide unequivocal evidence for a modulatory role of GABA and c

91 riginate in the paternal lineage and provide unequivocal evidence for an increase in mutation with pa

92 Lithium, valproate, and olanzapine had unequivocal evidence for efficacy in acute manic episode

93 We provide unequivocal evidence for EndMT at the invasive front of

94 and nonavian theropod species have provided unequivocal evidence for feathers and/or downlike integu

95 ions in the human-mouse comparison, we found unequivocal evidence for five independent intron losses

96 700 kyr ago) and thus represent the earliest unequivocal evidence for human presence north of the Alp

97 dation and antioxidant capacity, we obtained unequivocal evidence for oxidative stress in this disord

98 trials, but it has been difficult to obtain unequivocal evidence for robust clinical benefit.

99 These findings represent unequivocal evidence for saccadic suppression in human L

100 P, [CD(3)]-dThd and [CD(3),6D]-dThd, we find unequivocal evidence for T(5OH). formation and its conve

101 manipulation of the cell cycle and generated unequivocal evidence for the continuous accumulation of

102 Moreover, lessons from PID have provided unequivocal evidence for the essential role of regulator

103 cterization of JAM-C SC KO mice has provided unequivocal evidence for the involvement of SC JAM-C in

104 Using Bayesian model comparison, we found unequivocal evidence for the modulation of extrinsic (be

105 in solution and in the solid state provides unequivocal evidence for the presence of a Davydov split

106 w fluorescence and NMR experiments that give unequivocal evidence for the presence of a ternary DNA-N

107 The center of the controversy is the lack of unequivocal evidence in favor of myocardial regeneration

108 However, none of these therapies has shown unequivocal evidence in improving patient clinical statu

109 e the risk of mammary tumor development, but unequivocal evidence is still lacking.

110 Moreover, there is now unequivocal evidence linking dysbiosis to cancer develop

111 These findings provide unequivocal evidence of a functional interaction between

112 Together, these studies provide unequivocal evidence of a pathway of fibrogenesis that i

113 fants, research during recent years provided unequivocal evidence of active BAT in human adults.

114 ue differentiation in the alphaERKO provides unequivocal evidence of an obligatory role for ERalpha i

115 nd binding, a decrease in k(obs) with [L] is unequivocal evidence of conformational selection, but an

116 , the modified zonal elution method provides unequivocal evidence of direct interaction between RARga

117 y to synthesize LTB(4) and cysLTs, providing unequivocal evidence of efficient transcellular biosynth

118 cause none of its preserved anatomy provides unequivocal evidence of homology, without which comparat

119 lovis complex is considered to be the oldest unequivocal evidence of humans in the Americas, dating b

120 n, but an increase in k(obs) with [L] is not unequivocal evidence of induced fit.

121 Despite unequivocal evidence of ocean acidification (OA) via ope

122 ese reports shows that, so far, none provide unequivocal evidence of pre-Cretaceous angiosperms.

123 However, providing unequivocal evidence of the extent of their involvement

124 However, unequivocal evidence supporting the ferrireductase activ

125 This result provided unequivocal evidence supporting the notion that the 8-MO

126 This report provides the first unequivocal evidence that a bacterium is capable of cons

127 The crystal structure provides unequivocal evidence that a fully hydrated Mg(2+) ion ca

128 Most importantly, we find unequivocal evidence that ants are the sister group to b

129 finity (IC(50) in microgram ranges), provide unequivocal evidence that AuNP-BBN constructs are GRP-re

130 1/2-catalyzed cleavage reaction, and provide unequivocal evidence that CEs are retained within the CE

131 l trials began in 1989 and by 2002 there was unequivocal evidence that children with severe combined

132 Our data provide unequivocal evidence that CRACM1 multimers form the Ca(2

133 y virus in complex with D1D2-IgP, we present unequivocal evidence that D1D2-IgP can cross-link surfac

134 e societies-the major implication being that unequivocal evidence that eusociality evolved through th

135 sm for initiation of the PKS process provide unequivocal evidence that FabH is involved only in the F

136 TERPRETATION: For the first time, we provide unequivocal evidence that fibrin(ogen) is extensively de

137 ur results, thus, for the first time provide unequivocal evidence that infection of oligodendrocytes

138 Taken together, these results provide unequivocal evidence that menadione is a catabolic produ

139 our knowledge, this study provides the first unequivocal evidence that naive CD4(+) T cells can be ac

140 Unequivocal evidence that only the trimer containing two

141 We report unequivocal evidence that Pacific bluefin tuna, Thunnus

142 We provide unequivocal evidence that PD-1 is highly expressed (PD-1

143 of resource concentration, provide the first unequivocal evidence that population size is one of the

144 ulated Psp proteins has allowed us to obtain unequivocal evidence that PspA is not required for secre

145 stent with sperm competition theory, provide unequivocal evidence that sperm competition risk drives

146 However, as yet, few studies provided unequivocal evidence that the cerebellum is involved in

147 Here we present unequivocal evidence that the filamentous fungus Aspergi

148 These results provide the first unequivocal evidence that the substrate specificity of F

149 genomic fusion gene sequences, have provided unequivocal evidence that twin pairs of leukemia have a

150 transmission electron microscopy to provide unequivocal evidence that under near-physiological condi

151 Thus, our findings provide the first unequivocal evidence to explain the tolerability of mema

152 within the lumen of Wza, providing the first unequivocal evidence to our knowledge that nascent capsu

153 However, unequivocal evidence was only provided once mouse models

154 Unequivocal evidence, from mass spectral studies, indica

155 This also provides a rare unequivocal example of conditional reciprocity averting

156 Moreover, this is the first unequivocal example of successful engraftment of endocri

157 The youngest unequivocal examples occur in the middle Cambrian Marjum

158 ior with high fidelity, the stark absence of unequivocal examples of cumulative culture in nonhumans

159 ows that this conjecture is not supported by unequivocal experimental evidence.

160 Here we present unequivocal experimental proof that microscale cofactor-

161 The single most surprising and unequivocal finding was the lack of any detectable corre

162 Despite these unequivocal findings in rodents, similar changes cannot

163 te Triassic, are considerably older than the unequivocal fossil record of flowering plants or than th

164 Only 5 states offer unequivocal funding to schools for purchasing AEDs.

165 Systemic Vasculitides enrolled patients with unequivocal GCA.

166 These findings provide the first unequivocal genetic evidence for an essential physiologi

167 y, the spectrum of driver mutations provided unequivocal genomic evidence for a direct mutagenic role

168 atment with insulin-like growth factor I for unequivocal growth hormone insensitivity improves but do

169 T findings that occupy the gray area between unequivocal health and definite disease, with a particul

170 so examined and their levels do not indicate unequivocal higher pathway activity in tumors with mutat

171 Cellular identification of GDNF by unequivocal histochemical methods demonstrated that in n

172 n whom adequate material was obtained and an unequivocal histologic diagnosis was given, the sensitiv

173 ith the highly attenuated mutants, there was unequivocal HMPV replication at each anatomical site in

174 pted additional sampling, which confirmed an unequivocal hormone gradient.

175 This combination of techniques provided unequivocal identification and confirmation of diphenhyd

176 This allows for unequivocal identification and quantitation of new vesse

177 basic morphological information allowed the unequivocal identification at the species level of 90% o

178 Herein we demonstrate for the first time the unequivocal identification of ABA within a monocytic T h

179 nd rapid diagnostic method developed for the unequivocal identification of ARD-associated adenoviral

180 ntation pattern of general applicability for unequivocal identification of covalently attached compou

181 h the known primary sequence of RyR1, enable unequivocal identification of CPM-adducted cysteines.

182 lentiviral transduction system to allow the unequivocal identification of live murine corticotrophs

183 eted metabolomics strategy with pipeline for unequivocal identification of metabolites using the MSML

184 Recent advances have led to the unequivocal identification of microorganisms responsible

185 ne residues presenting a major challenge for unequivocal identification of specific phosphorylation s

186 ver increasing, there is a need for fast and unequivocal identification of suspect organisms to suppl

187 s full scan and full scan MS/MS data for the unequivocal identification of target analytes.

188 Unequivocal identification of the full composition of a

189 e are subject to weak background noise only, unequivocal identification of the hidden node can be ach

190 irradiation with lambda = 340 nm led to the unequivocal identification of the nitrile ylide anti-4,

191 f linkage on chromosome 16 (IBD1) led to the unequivocal identification of the NOD2 gene (now called

192 characteristic spatial mosaics and afforded unequivocal identification of the parasol cells among di

193 ased on a hierarchical sampling strategy and unequivocal identification of the region of interest, se

194 this methodology not only permitted for the unequivocal identification of the six targeted species a

195 arge populations of lysenin channels allowed unequivocal identification of the unmodified analyte by

196 itol pyrophosphates in their seed, providing unequivocal identification of their presence in plant ti

197 firmed that the use of DNA barcoding allowed unequivocal identification of this new pest from Ghana b

198 This enabled unequivocal identification of tumor cells emerging from

199 labeling in cell culture method enables the unequivocal identification of tyrosine kinase substrates

200 mozygous presence of the deletion allows the unequivocal identification of Vel-negative blood donors.

201 are essential pieces of information for the unequivocal identification, detection, and confirmation

202 onal tandem mass spectrometry cannot provide unequivocal identification.

203 MS/MS data and requires using MS/MS data for unequivocal identification.

204 Eight participants (5.2%) presented unequivocal IgE-mediated reactions to peanut upon introd

205 al cells alone representing the only site of unequivocal IL-6 receptor expression.

206 Design, Setting, and Participants: Unequivocal in situ melanoma without associated nevi or

207 secutive cases (33%) of previously diagnosed unequivocal in situ melanoma.

208 These results provide the first unequivocal in vitro evidence that TEII can hydrolyze ac

209 ough correlated equivalence points providing unequivocal, in situ evidence that identifies how SOFC p

210 ame promoter as the shRNA, thus providing an unequivocal indicator, not only to the cells that expres

211 ls analysed provide evidence for limited but unequivocal interaction between water and the volcanic r

212 e more complex than is often assumed, and an unequivocal interpretation of fMRIa results can be achie

213 atus was often different between metastases, unequivocal intra-tumor heterogeneity was not found in i

214 of knock-in mice through the conditional and unequivocal labeling of insulin fused to the SNAP tag.

215 The new evidence presented here for unequivocal lethal violence on a large scale is put into

216 he northwest Indian Ocean, where, despite an unequivocal link between an onshore flood basalt provinc

217 These results provide the first unequivocal link between mammalian meiotic aneuploidy an

218 components linkage analysis resulted in the unequivocal localization of two genes (one on chromosome

219 edge structure investigations revealed in an unequivocal manner the formation of up to about 60% of C

220 The only unequivocal matches for a sterol biosynthetic pathway we

221 , the collective mass in graphene has defied unequivocal measurement.

222 SILV, GDF15, and L1CAM normalized to TYR in unequivocal melanoma versus benign nevi resulted in an a

223 agenesis data allowed the construction of an unequivocal model of dimeric H(C) in solution.

224 uced DNA double-strand breaks is profuse and unequivocal; moreover, it is clear that the RAG complex

225 a bilaterally symmetrical body, there are no unequivocal morphological characters to support placemen

226 To date, unequivocal neuroanatomical features have been demonstra

227 en adequately studied because of the lack of unequivocal nomenclature.

228 ations of NO donors also stimulate rapid and unequivocal nuclear retention of p53 but apparently do n

229 periodontitis-chronic and aggressive-lack an unequivocal, pathobiology-based foundation.

230 There were no unequivocal pathogenic changes.

231 or lower stages, only the IRSS considers all unequivocal pathological prognostic factors.

232 derperformance or partial stent obstruction, unequivocal patterns of focal outflow enhancement by TMB

233 However, in this study a straightforward unequivocal peak assignment was achieved for all unknown

234 only known impact structure on Earth with an unequivocal peak ring, but it is buried and only accessi

235 corded on activation of the M-cell, allowing unequivocal physiological identification of the M-cell a

236 es has produced differences in opinion, from unequivocal positive evidence to no evidence at all for

237 Few if any studies have demonstrated the unequivocal presence of intracellular ABA.

238 Besides age, unequivocal presence of spinal cord lesions and being ma

239 uch as measurement of size and definition of unequivocal progression, also are addressed.

240 ported by rapidly growing experimental data, unequivocal proof has been elusive.

241 These findings provide unequivocal proof of the allosteric nature of thrombin a

242 early Chinese salt production have provided unequivocal proof.

243 separated from other HE-derived products for unequivocal quantification.

244 ped disease recurrence following an initial, unequivocal radiologic complete regression after T-cell-

245 a small number of animal models by utilizing unequivocal rare disease mutations and targeted cognitiv

246 Our unequivocal realization of the "molecules to device" con

247 rate a paleomagnetic methodology that allows unequivocal recognition of detachment-mode seafloor spre

248 The oldest unequivocal record of a sauropterygian is also from the

249 ntrol (IGC) targeting HbA1c fails to show an unequivocal reduction of macrovascular complications in

250 first study, the median time to the onset of unequivocal relief from an attack was 2 hours in the sub

251 imary end point was the time to the onset of unequivocal relief.

252 findings remain preliminary due to a lack of unequivocal replication and the failure to control fully

253 Unequivocal replications remain the top priority.

254 An unequivocal requirement for this approach is the biocomp

255 Unequivocal research on cAMP-mediated signaling in such

256 ectivity information on all isomers allowing unequivocal resonance assignment, and this approach to s

257 een unable to find any definitive tests with unequivocal results showing that risk-spreading has been

258 PCR yielded unequivocal results with adequate DNA isolated in 24 cas

259 classical NMR data analysis fails to provide unequivocal results.

260 Pappaceras is the earliest known unequivocal rhinocerotoid, and the holotype of the new s

261 These data demonstrate an unequivocal role for common genetic variants in the etio

262 ation of Wnt/beta-catenin signaling plays an unequivocal role in colorectal cancer, but identificatio

263 Despite the unequivocal role of B lymphocytes as effecter cells in h

264 n screens and microarray data established an unequivocal role of VGSC SCN5A as a high level regulator

265 Data reveal an unequivocal rostral-to-caudal progression of both dorsal

266 necessitates at least dual-element CSIA for unequivocal SA in the presence of degradation-induced is

267 idney transplantation is recommended, but no unequivocal screening strategy has yet been identified.

268 Even though FA cells demonstrate unequivocal sensitivity to crosslinkers, such as mitomyc

269 ion (N2E) in the amino terminal domain allow unequivocal separation of the two gating processes in a

270 erved at all internal energies, allowing for unequivocal sequence assignment.

271 To date, this precludes proposing an unequivocal sex-dependent susceptibility to influenza.

272 divergent Xenopus laevis XNC10 gene and its unequivocal Silurana (Xenopus) tropicalis orthologue, SN

273 panning amino acids 759-775 of pol I, is the unequivocal site of the template cross-linking.

274 on, new diagnostic primers were designed for unequivocal species and type assignments for RV-C isolat

275 bodies, in contrast, are very rare: only two unequivocal specimens have been reported, both from the

276 tu synchrotron infrared experiments show the unequivocal spectroscopic signature of the high-pressure

277 ntified DNA sequence variations that exhibit unequivocal statistical associations with many common ch

278 Herein we demonstrate that unequivocal step-change shifts in micelle populations oc

279 e, and nonclassical subsets, but there is no unequivocal strategy to dissect the latter 2 cell types.

280 been studied for nearly a century and yet an unequivocal structural description of this material rema

281 Revelation of unequivocal structural information at the atomic level f

282 mental PES and simulated spectra provides us unequivocal structural information to fully solve the gl

283 Despite its conserved presence, unequivocal study of Hrd3 function has been precluded by

284 ch as binocular rivalry, features periods of unequivocal subjective disappearances despite constant p

285 The unequivocal success of B-cell-depleting agents in reduci

286 n settlement of the island failed to provide unequivocal support for either scenario.

287 manipulation in nature, this study provides unequivocal support for frequency-dependent survival--an

288 ture of canonical alpha-helices and provides unequivocal support for our helix nucleation strategy.

289 Effort ratings provided unequivocal support for swallowing inhibition, with a th

290 han humans may reflect problems in producing unequivocal support for the occurrence of teaching, rath

291 ies-level coevolved traits) does not provide unequivocal support for the theory.

292 to be deeply nested members of Annelida, and unequivocal support is found for Micrognathozoa as the s

293 This result adds unequivocal support to the view that the PHC mediates co

294 odern, but are too poorly preserved to allow unequivocal taxonomic placement.

295 w taxon was claimed to represent the oldest "unequivocal" termitophile so far discovered, pushing bac

296 tudies for complex cardiovascular disease is unequivocal, thus mandating the expansion of resources f

297 ting specific types of systemic amyloidoses, unequivocal typing of amyloid deposits is now essential.

298 Although ketamine has unequivocal uncompetitive inhibitory effects on N-methyl

299 l protein synthesis, thus allowing the first unequivocal visualization of two mtDNAs at the nucleoid

300 To the question in the title, we answer an unequivocal "yes" but maybe not necessarily in the areas