ライフサイエンスコーパス: unfavourable

1 an aqueous protein channel is energetically unfavourable.

2 through this channel is highly energetically unfavourable.

3 Overall, prognosis appears unfavourable.

4 zed as survival/death and also as favourable/unfavourable.

5 infants without decreasing the incidence of unfavourable advanced-stage disease in older children.

6 EACOPP escalated has been evaluated in early unfavourable and advanced Hodgkin Lymphoma and led to an

7 on process folded monomers are energetically unfavourable and consequently never become populated to

8 of barnase and barstar are, however, always unfavourable and in most cases larger than the effects o

9 to twice their ground speed, indicating that unfavourable and potentially fatal weather conditions ar

10 nts with early-stage favourable, early-stage unfavourable, and advanced-stage Hodgkin's lymphoma from

11 s are generally considered to be kinetically unfavourable, as described by Baldwin's rules.

12 lux of divalent cationic drugs energetically unfavourable, as it requires exchange with at least two

13 ts also suggest that oxygen vacancies become unfavourable at high pressures, in which case only the p

14 ergy barriers and is therefore thought to be unfavourable at room temperature unless nanoscale holes

15 impractically high thresholds owing to their unfavourable bandstructures.

16 rapid socioeconomic shifts that have led to unfavourable changes in lifestyle such as increased toba

17 mechanism for the origins of life because of unfavourable chemical conditions on the planet and the h

18 ow mood in humans is an adaptive response to unfavourable circumstances, and that the anhedonia, pess

19 for supporting populations during periods of unfavourable climate change and in facilitating rapid mi

20 ct populations to persist despite regionally unfavourable climate.

21 y contrast, high-risk neuroblastomas have an unfavourable clinical course despite intensive multimoda

22 Childhood maltreatment predicts unfavourable clinical features and course of illness in

23 sed in TNBC patients and are associated with unfavourable clinical outcomes.

24 e concentration ratio between favourable and unfavourable compounds throughout ripening, could be sta

25 (predictive germination), spread the risk of unfavourable conditions (bet hedging) or both (integrate

26 periods of transition between favourable and unfavourable conditions for growth (i.e. fall).

27 ves for reproduction and for survival during unfavourable conditions, the accumulation of lipids repr

28 state of suspended development triggered by unfavourable conditions.

29 ability of tumours to continue growing under unfavourable conditions.

30 orces to trap molecules in thermodynamically unfavourable configurations.

31 irst conferring cardioprotection even in the unfavourable context of renal failure, extending the evi

32 y had the highest odds ratios (OR) of having unfavourable CVD risk factors compared to those in the n

33 3 additonal cycles, whereas patients with an unfavourable decline were randomly assigned (1:1) to rec

34 al sweat bees have pushed the limits of this unfavourable design so far that they can navigate using

35 odynamic penalty to binding derived from the unfavourable desolvation of 1,8 octan-diol is partially

36 D14 trial enrolled patients with early-stage unfavourable disease from Jan 28, 2003, to Dec 23, 2009;

37 implementation, 20 (33%) of 60 patients had unfavourable disposition and 40 (67%) had favourable dis

38 implementation, 33 (52%) of 63 patients had unfavourable disposition at hospital discharge (death or

39 This entropically unfavourable DNA or RNA packaging is accomplished by an

40 in vs. loss) but not outcome (favourable vs. unfavourable) during reward consummation.

41 FAs and trans fatty acids, which may have an unfavourable effect on health.

42 with adverse effects on quality of life and unfavourable effects on long-term outcomes, raising the

43 and females operate sperm selection against unfavourable ejaculates (cryptic female choice).

44 election decreases again towards zero as the unfavourable ejaculates become disastrous (i.e. as their

45 from zero as the viability of offspring from unfavourable ejaculates falls below that of favourable e

46 proved difficult to develop, reflecting the unfavourable electrochemical properties of known, electr

47 ular, the initial BD simulations neglect the unfavourable electrostatic desolvation effects that resu

48 Unfavourable energy barriers to helium and hydrogen tran

49 An inherent obstacle to that end is the unfavourable energy level offset at hybrid inorganic/org

50 As a result of unfavourable entropic terms, highly dynamical regions ar

51 th a large favourable enthalpy change and an unfavourable entropy change.

52 es suggest that the X chromosome presents an unfavourable environment for the expression of genes in

53 to ensure resource capture is optimised and unfavourable environments are avoided.

54 s (making poor use of the enzyme) or promote unfavourable equilibria (giving low conversions).

55 ge activation energies make it energetically unfavourable for a classical, over-the-barrier mode of c

56 SET-PT also proved to be thermodynamically unfavourable for all three molecules in the solvents con

57 supposed latency and lag might appear to be unfavourable for an involvement in fast processing, this

58 ide chain of Ser75 adopts a position that is unfavourable for catalysis, indicating that this site ma

59 e presence of their host, causing conditions unfavourable for local conspecific recruitment.

60 ipid domains are thought to be energetically unfavourable for membrane fusion, rafts have long been i

61 ical surface (13.7 +/- 1.8 mV) and therefore unfavourable for passive movement of SCN(-).

62 repression of hilA expression by conditions unfavourable for Salmonella invasion.

63 he independent data monitoring committee was unfavourable for the afatinib group.

64 the interband excitation of BiVO4, which is unfavourable for the hot electrons accumulation in BiVO4

65 The main outcome measures were mortality and unfavourable functional outcome (modified Rankin Score:

66 (OR: 0.66; 95% CI 0.42 to 1.05, p=0.077) and unfavourable functional outcome at discharge (OR: 0.77;

67 he grain-boundary structure is random, a few unfavourable grain boundaries may dominate device perfor

68 ence of the course and its unique obstacles, unfavourable ground conditions (too soft or too hard), a

69 Maf1 is a phospho-integrator, with unfavourable growth conditions leading to rapid Maf1 dep

70 on of phosphorylated FDH and, in response to unfavourable growth conditions, reduction in FDH phospho

71 ic pressure, high ultraviolet radiation, and unfavourable growth temperatures.

72 It is now widely accepted that unfavourable haemodynamic conditions play an essential r

73 y-stage favourable (HD13 trial), early-stage unfavourable (HD14 trial), and advanced-stage (HD15 tria

74 er external bias that leads to energetically unfavourable head-to-head domain walls in as-grown epita

75 ation of 6.9 +/- 3.7 risk factors (including unfavourable health behaviours, health and functional im

76 logical tests which predict the induction of unfavourable IgG antibodies enhancing the binding of IgE

77 cked crystal structures become energetically unfavourable in comparison with the complex-structured B

78 ferroelectric walls, which are energetically unfavourable in general, were found to be mysteriously a

79 association rates, because even if they are unfavourable in the fully formed complex, they are still

80 The unfavourable interactions made by the ligands at the hae

81 ne amide to another, is typically plagued by unfavourable kinetic and thermodynamic factors.

82 is occurs because males avoid expenditure in unfavourable matings, to conserve sperm for matings in t

83 ys a pivotal role in shaping a metabolically unfavourable microenvironment in adipose tissue during c

84 thalamic volume (p < 0.0001), and predicted unfavourable motor outcome at a median (range) corrected

85 tomized into favourable (mRS 0-2, n=210) and unfavourable (mRS 3-6;n=115).

86 fferent mRNA patterns between favourable and unfavourable neuroblastomas, both in the subgroups with

87 arisations are independently associated with unfavourable neurological outcome.

88 id sequences is complicated by energetically unfavourable non-ideal features--for example kinked alph

89 plication of this technique to energetically unfavourable or demanding reactions.

90 cient compared with wild type because of the unfavourable orientation of Ser1 towards incoming substr

91 h parts of the molecule assume energetically unfavourable orientations.

92 trength' and respond metabolically to offset unfavourable osmotic intracellular solute concentrations

93 SD were associated with an increased risk of unfavourable outcome (common odds ratios 1.56 [95% CI 0.

94 7%) of 30 patients with APOE epsilon4 had an unfavourable outcome (dead, vegetative state, or severe

95 ly as those without APOE epsilon4 to have an unfavourable outcome 6 months after head injury.

96 with 36% of APOE epsilon4 carriers having an unfavourable outcome compared with 33% of non-carriers o

97 miR-214 (2.4 [1.2-4.5]) were associated with unfavourable outcome in overall survival independent of

98 baseline level (overshoot); in subjects with unfavourable outcome maximum PCr recovery was lower than

99 e at 5 years, compared to <15% in those with unfavourable outcome predictors.

100 7 patients in the early surgery group had an unfavourable outcome versus 178 (62%) of 286 patients in

101 = 8, intermediate outcome) or severe (n = 5, unfavourable outcome) secondary energy failure at 24 h a

102 reading depolarisations were associated with unfavourable outcome, after controlling for conventional

103 tion/favourable outcome, n=7; 11q alteration/unfavourable outcome, n=14; no 11q alteration/favourable

104 /favourable outcome, n=81; no 11q alteration/unfavourable outcome, n=8; tumours with MYCN amplificati

105 re discharged home, of whom 104 (60%) had an unfavourable outcome.

106 ) formation further increases the odds of an unfavourable outcome.

107 prognosis-based dichotomised (favourable or unfavourable) outcome of the 8 point Extended Glasgow Ou

108 programmatically incurable tuberculosis and unfavourable outcomes (treatment failure, relapse, defau

109 es that aid the prediction of favourable and unfavourable outcomes can provide patients with the most

110 ncoding in D2R-expressing NAc cells of prior unfavourable outcomes during decision-making.

111 ls in the nucleus accumbens (NAc), signalled unfavourable outcomes from the recent past at a time app

112 bly associated with increased probability of unfavourable outcomes whereas white race (p=0.01), use o

113 nal recovery but being underweight predicted unfavourable outcomes.

114 sociated with aggressive forms of cancer and unfavourable outcomes.

115 eatment burden' and has been associated with unfavourable outcomes.

116 hat readily-metabolisable carbon sources and unfavourable pH in the rhizosphere/egg-mass environment

117 ly, the lipophilicity of moenomycin leads to unfavourable pharmacokinetic properties that render it u

118 d infection, but they are costly and display unfavourable pharmacokinetics.

119 bust means of organizing NPs in a chemically unfavourable polymer.

120 mpared to 1985-1999, suggesting increasingly unfavourable post-fire growing conditions, corresponding

121 We identified the following variables as unfavourable predictors of survival.

122 A multivariate model retained the following unfavourable predictors of survival: (i) falls within 3

123 to drive DNA supercoiling, an energetically unfavourable process.

124 ectively producing a desired but kinetically unfavourable product for the important carbon dioxide hy

125 ry B-cell non-Hodgkin lymphoma (NHL) have an unfavourable prognosis with few treatment options.

126 cursor acute lymphoblastic leukaemia have an unfavourable prognosis.

127 defines a subgroup of primary melanomas with unfavourable prognosis.

128 of various tumors and is associated with an unfavourable prognosis.

129 m 435 patients corresponds to an independent unfavourable prognostic indicator.

130 Consequently, FoxA1 downregulation, an unfavourable prognostic sign in certain advanced prostat

131 This is due to unfavourable ratios of elastic to inelastic scattering a

132 mes that utilize chemical energy to catalyse unfavourable reactions.

133 olic coupling that can accommodate otherwise unfavourable reactions.

134 avoid environments where carbon deficiency, unfavourable reduction potential or other insults would

135 r publication of low-quality papers, wherein unfavourable results are incompletely described.

136 transplantation; however, most patients with unfavourable risk factors progress after transplantation

137 ed trials of citalopram and venlafaxine show unfavourable risk-benefit profiles.

138 Patients with unfavourable-risk relapsed or primary refractory classic

139 general, are limited by modest efficacy and unfavourable side-effects.

140 erm selection (measured as the proportion of unfavourable sperm eliminated) by paying a fecundity cos

141 The unfavourable Ss and ss genotypes were over-represented i

142 ligand binding in the T state may result in unfavourable stereochemistry in and around the haem-liga

143 clusters of amino acids around each of these unfavourable substitutions using Monte Carlo sampling.

144 ical cryosections, which normally provide an unfavourable substrate for growth.

145 and autonomic laboratory features predicted unfavourable survival in a univariate analysis.

146 gainst gravity and overcome the effect of an unfavourable temperature gradient.

147 rs after a meal and in conditions when it is unfavourable to eat, such as during illness or exposure

148 ppetite suppression in conditions when it is unfavourable to eat.

149 1 (56%) of 109 patients, and conversion from unfavourable to favourable circulating tumour cell count

150 so enhanced polyadenylation under conditions unfavourable to splicing.

151 Since membrane depolarization is unfavourable to the influx of Ca2+ through the CRAC chan

152 pa-casein and alpha-tocopherol contents, and unfavourable traits, such as the higher concentrations o

153 Reports of unfavourable treatment outcomes by caregivers were highe

154 with poor prognosis germ-cell tumours and an unfavourable tumour marker decline.

155 able marker assessment, and 203 (80%) had an unfavourable tumour marker decline; 105 were randomly as

156 regulation of 11q genes was observed only in unfavourable tumours with 11q loss.

157 gradients to catalyse the thermodynamically unfavourable uptake of essential nutrients, neurotransmi

158 ocity at which drones fly, viewing distance, unfavourable vantage points, and ambient conditions.

159 urable (having high viability or success) or unfavourable (where progeny are less successful).