1 Unfortunately,
1 has potent human ether-a-go-go-related
2 Unfortunately,
a disconnect remains between human percep
3 Unfortunately,
a lack of both structural and functional
4 Unfortunately,
a low permeability of siRNA through the s
5 Unfortunately,
a quantitative study of the diffusion per
6 Unfortunately,
a single approach is not effective for in
7 Unfortunately,
aberrant splicing events do occur which h
8 Unfortunately,
about 39% of the antibodies evaluated for
9 Unfortunately,
ABR wave-I is difficult to measure in hum
10 Unfortunately,
accurate analysis of EVs cargo faces a ch
11 nanomaterials to organic molecular dyes, yet
unfortunately all water-soluble organic molecules with >
12 Unfortunately,
all current methods for the syntheses of
13 Unfortunately,
all current NIR-II fluorophores are excre
14 Unfortunately,
all of Aristotle's writings about plant f
15 cles into or out of the channels, but it is,
unfortunately,
an extremely inefficient transport mechan
16 Unfortunately,
an ophthalmologist's interpretation is pr
17 Unfortunately,
anti-D monoclonal antibodies have been, a
18 ling a decline in adaptive homeostasis that,
unfortunately,
appears to manifest with ageing, especial
19 Unfortunately,
application of CAR T cell-mediated therap
20 Unfortunately,
approximately 20% of successfully treated
21 Unfortunately,
as we demonstrate, LMM estimates of herit
22 Unfortunately,
assembly pathways of the structurally sim
23 Unfortunately,
AST for vancomycin is relatively slow and
24 Unfortunately,
at present, chocolate products contain to
25 Unfortunately,
at the very low particle concentrations w
26 Unfortunately,
atomistic molecular dynamics (MD) simulat
27 Unfortunately,
attempts to target K-ras-mutant lung tumo
28 Unfortunately,
attenuation or prevention of the toxic ef
29 Unfortunately,
B. pertussis has relatively slow growth i
30 Unfortunately,
balanced-detection increases OCT system s
31 Unfortunately,
bigger frit pores result in larger flow r
32 Unfortunately Bloom-Richardson (BR) grade determined by
33 Unfortunately,
both of these anodes require a reliable p
34 Unfortunately,
both of these approaches can match multip
35 Unfortunately,
cancer cells become resistant to these dr
36 Imminent divergences of compressibility etc.
unfortunately cannot be confirmed due to pre-emption by
37 Unfortunately,
carrying out reactions with radicals in a
38 Unfortunately,
chemical inhibitors of PERK's kinase acti
39 Unfortunately,
chloramination of waters treated with qua
40 Unfortunately,
chronic activation of these adaptations u
41 Unfortunately,
clinically used tocolytics are frequently
42 Unfortunately,
cnidarians have thus far been relatively
43 Unfortunately,
commercially available programs do not al
44 Unfortunately,
comparatively little is known about the c
45 Unfortunately,
competing models of Earth's composition r
46 tions, they exhibit a pH cross-response that
unfortunately complicates the identification of the end
47 Unfortunately,
compounds containing these chemotypes hav
48 Unfortunately,
conventional fMRI only indirectly assesse
49 Unfortunately,
conventional optical imaging cannot provi
50 Unfortunately,
current commercially available detection
51 Unfortunately,
current hyphenated 2D separations are lim
52 Unfortunately,
current implementations, in animal and cl
53 Unfortunately,
current interventions are only modestly e
54 Unfortunately,
current methods of gene delivery treat on
55 Unfortunately,
current methods suffer from invasiveness,
56 Unfortunately,
current methods to measure biomechanical
57 Unfortunately,
current multiset methods all use binary i
58 Unfortunately,
current PDB files do not provide exact an
59 Unfortunately,
current succinct de Bruijn graph represen
60 Unfortunately,
current treatment strategies have limited
61 Unfortunately,
current treatments that broadly inhibit O
62 Unfortunately,
currently available diagnostic methods ca
63 Unfortunately,
D4 antagonists that were developed for sc
64 Unfortunately,
data on trends in diabetes-related compli
65 Unfortunately,
delivering drugs into skin is extremely d
66 Unfortunately,
despite the rise in preventive chemothera
67 Unfortunately,
determining whether this is the case is k
68 Unfortunately,
diagnosis can be difficult, due to numero
69 Unfortunately,
donor lymphocyte infusion induced severe
70 Unfortunately,
due to logistical difficulties and high c
71 Unfortunately,
effective treatments for TBI remain elusi
72 Unfortunately,
efforts toward a high resolution structur
73 Unfortunately,
EM, in its base form, requires long solve
74 Unfortunately,
empirical research on trophic rewilding i
75 Unfortunately,
even with the simplification of a constan
76 Unfortunately,
evidence suggests that a high proportion
77 Unfortunately,
existing optical clearing approaches pres
78 Unfortunately,
existing treatments have limited efficacy
79 Unfortunately,
experimental challenges and the large num
80 Unfortunately,
experiments using cryogenic buffer gases
81 Unfortunately,
few chambers exist in the world, and this
82 Unfortunately,
few high-quality, randomized data to supp
83 Unfortunately,
few of these questions can be readily ans
84 Unfortunately,
few prospective data are available, so re
85 Unfortunately,
few resources are available to facilitate
86 Unfortunately for potential laser applications, this deg
87 Unfortunately,
for most crops, transformation and regene
88 Unfortunately,
for most fermentations, over one-third of
89 Unfortunately,
for most of these trials that have focuse
90 Unfortunately,
for patients with cleft palate-one of the
91 with reperfused acute myocardial infarction;
unfortunately,
for these drugs, no information on their
92 Unfortunately,
fragmentation spectra cannot identify mol
93 Unfortunately,
GraphProt cannot detect structural prefer
94 Unfortunately,
hardware restrictions often limit the sen
95 Unfortunately,
health care resources are limited.
96 Unfortunately HIV-1 evolves rapidly and may readily prod
97 Unfortunately,
however, the highly valuable spectroscopi
98 Unfortunately,
however, these frequencies, upon which bo
99 Unfortunately,
however, this tumor response is generally
100 Unfortunately,
imaging is not sufficient to constrain th
101 Unfortunately,
immunization with recombinant E2 and E1E2
102 Unfortunately,
in 2D/2D heterojunctions, for a given com
103 Unfortunately,
in contrast to axons from the peripheral
104 11 was selected for further profiling, but,
unfortunately,
in GLP toxicological studies it showed li
105 Unfortunately,
in most countries, routine implementation
106 Unfortunately,
in soluble form they readily enter system
107 Unfortunately,
inexperienced physicians ordering the ECG
108 Unfortunately,
inhibition of Fc function by deglycosylat
109 Unfortunately,
inhibitor effects on protein activity can
110 Unfortunately,
integrated electrodes close to the cellul
111 Unfortunately,
interruption of ART almost invariably res
112 Unfortunately,
IP is a labor-intensive technique, is dif
113 Unfortunately,
isolated human VH domains also generally
114 ily dynamics and function in other ways, and
unfortunately,
it can also be associated with mortality,
115 g gene, localizing and stabilizing proteins;
unfortunately,
it is also involved with many major disor
116 Unfortunately,
it is currently difficult to evaluate the
117 Unfortunately,
it is hard to define, evaluate, and achie
118 Unfortunately,
it lacks the infrastructure needed to sup
119 14-3-3 protein in cerebrospinal fluid (CSF),
unfortunately lacks specificity when confronting a rapid
120 Unfortunately,
large-scale effects of these structures r
121 Unfortunately,
little is known about how the dopamine (D
122 Unfortunately,
little progress has been made in elucidat
123 Unfortunately,
little structural information is availabl
124 Unfortunately,
liver failure worsened dramatically while
125 Unfortunately,
many cancer cells use immune evasion stra
126 Unfortunately,
many cancer treatments increase the risk
127 Unfortunately,
many of the most advantageous properties
128 Unfortunately,
many patients die on the waiting list hop
129 Unfortunately,
many patients do not respond or inevitabl
130 Unfortunately,
many patients still fail to respond to th
131 Unfortunately,
many protein families are highly divergen
132 Unfortunately,
mda-7/IL-24 application in pancreatic can
133 Unfortunately,
measurements of dynamic heterogeneities t
134 Unfortunately,
measuring moisture diffusivity is not tri
135 Unfortunately,
mixed halide perovskites undergo phase se
136 Unfortunately,
models that predict emissions of and the
137 Unfortunately,
modifying device performance or changing
138 th food and wines can refine our pallet (and
unfortunately more quickly empty our wallet), and with y
139 Unfortunately,
more and more sepsis patients, especially
140 m domain families no structure is known, but
unfortunately most of these families have at most a few
141 Unfortunately,
most adjuvant formulations fail to induce
142 Unfortunately,
most if not all TFETs are operational onl
143 Unfortunately,
most materials produced using mu3D printi
144 Unfortunately,
most of the existing computational method
145 Unfortunately,
most of the precipitation hardened alumin
146 Unfortunately,
most patients fail to remit.
147 Unfortunately,
most techniques do not provide a direct m
148 Unfortunately,
nanoparticle additives are restricted to
149 Unfortunately,
negative margins are not always surgicall
150 inadequate, or as bridge to transplant, but
unfortunately,
no evidence in randomized controlled tria
151 Unfortunately,
no such rules have been discovered for pr
152 Unfortunately,
none of these strategies provided the des
153 Unfortunately,
not all patients respond to anti-TNF ther
154 Unfortunately,
OB is poorly understood and often results
155 ic resolution with fewer particle images, it
unfortunately obscures some biologically interesting com
156 Unfortunately,
omega 3 supplements have not been shown t
157 Unfortunately,
only a subgroup of patients responds and
158 Unfortunately,
other capabilities are eclipsed by the di
159 Unfortunately,
our current understanding of how influenz
160 Unfortunately,
our current understanding of the biologic
161 h diversity includes annelid polychaetes but
unfortunately,
our understanding of such fauna is limite
162 Unfortunately,
patients are less likely to seek care as
163 Unfortunately,
PDT is often followed by recurrence due t
164 Unfortunately,
performance with hearing aids and the ben
165 Unfortunately,
phase evolutions inside such small partic
166 Unfortunately,
present-day methods for probing the perfo
167 Unfortunately,
previously reported triboelectric fiber a
168 Unfortunately,
primary HIV-1 infection results in the ma
169 Unfortunately,
problems among meta-analyses such as the
170 Unfortunately,
progress has been slow and the current ap
171 Unfortunately,
progress in developing chelators for medi
172 Unfortunately,
protein measurement in DBS is hindered by
173 Unfortunately,
resistance to these agents frequently occ
174 Unfortunately,
response rates for this strategy remain l
175 ressive device processing is often required,
unfortunately resulting in strong disorder that masks th
176 Unfortunately,
RNA aptamers are susceptible to degradati
177 Unfortunately,
RNA degrades too rapidly to be recovered
178 Unfortunately,
robust preparation of highly active extra
179 Unfortunately,
Rosetta is largely a command-line-driven
180 Unfortunately,
routinely and easily measured experimenta
181 Unfortunately,
safe and effective vaccines against most
182 However,
unfortunately,
sensors capable of providing potassium im
183 Unfortunately,
severe oxygen deprivation carries a high
184 try industry to control avian mycoplasmosis;
unfortunately,
some vaccines may revert to virulence and
185 Unfortunately,
standard mathematical modeling practices
186 Unfortunately,
studies show that many patients do not pr
187 Unfortunately,
studies thus far have focused on exponent
188 Unfortunately,
subsequent studies have shown that althou
189 h is desirable for certain applications, but
unfortunately such FX-nonbinding vectors also become sen
190 Unfortunately,
such an approach prohibits the measuremen
191 Unfortunately,
such rewiring of cellular metabolism is o
192 Unfortunately,
such strategies can limit the ability of
193 Unfortunately,
synergistic application of more than a si
194 Unfortunately,
TAA is not easily ionized by regular elec
195 Unfortunately,
targeted therapies thus far have been uns
196 Unfortunately,
tests such as hemoglobin A1c (HbA1c)/fast
197 ld type cell lines clearly demonstrated that
unfortunately the 13-gene signature cannot predict respo
198 Unfortunately the performance of these detectors deterio
199 Unfortunately the translation to nematode pathogens has
200 Unfortunately,
the alignment methods proposed thus far d
201 Unfortunately,
the antibiotic pipeline does not match he
202 Unfortunately,
the application of these second-generatio
203 Unfortunately,
the associated tests used for assessing t
204 Unfortunately,
the available P2RX7 knock-out mice genera
205 Unfortunately,
the B lymphocyte-directed T1D interventio
206 Unfortunately,
the characterization of molecules encoded
207 Unfortunately,
the clinical outcomes of TLE cannot be de
208 Unfortunately,
the compound is a potent inhibitor of cyt
209 Unfortunately,
the creation of on/off state differences
210 Unfortunately,
the current efficiency of the process is
211 Unfortunately,
the current suite of DNA-specific privacy
212 Unfortunately,
the design choices made by existing haplo
213 Unfortunately,
the development of new chemotherapeutics
214 Unfortunately,
the ductility of magnesium alloys is usua
215 Unfortunately,
the ecophysiological forces that constrai
216 Unfortunately,
the efficacy of these treatments is often
217 Unfortunately,
the engineering of cyanobacteria to creat
218 Unfortunately,
the etamax values vary greatly depending
219 Unfortunately,
the extensive application of label-free b
220 Unfortunately,
the extremely high doses of HPbetaCD requ
221 Unfortunately,
the fastest-reacting cyclopropenones are
222 Unfortunately,
the field has seen only minimal therapeut
223 Unfortunately,
the genetic mechanisms underlying cranioc
224 Unfortunately,
the high number of (1)H-(1)H couplings gi
225 Unfortunately,
the identification of the unique cell sur
226 Unfortunately,
the included nanocrystals may also act as
227 Unfortunately,
the industrial implementation of the soft
228 Unfortunately,
the intricacy of the natural complexes ma
229 Unfortunately,
the kidney transplant waiting list has ba
230 Unfortunately,
the lack of soft-tissue evidence in the f
231 Unfortunately,
the lack of structure in radiologic repor
232 Unfortunately,
the landscape of human E3-substrate netwo
233 Unfortunately,
the Laplacian does not take into account
234 Unfortunately,
the long-range coupling information betwe
235 Unfortunately,
the luminescent properties of these emitt
236 Unfortunately,
the material records of history of this r
237 Unfortunately,
the mechanism of this transformation is s
238 Unfortunately,
the mechanisms by which breast cell fate
239 Unfortunately,
the more practically usable bulk and mult
240 Unfortunately,
the number of mixtures that can be formed
241 Unfortunately,
the onset and effects of ADEs are often u
242 Unfortunately,
the optimal luciferases for imaging in vi
243 Unfortunately,
the patient died one week after diagnosis
244 Unfortunately,
the potential for such errors is signific
245 Unfortunately,
the prediction and even the experimental
246 Unfortunately,
the rapid regulation of dopamine signalin
247 Unfortunately,
the strategies for increasing their stren
248 ith specific biological or medical outcomes;
unfortunately,
the structure elucidation process of unkn
249 Unfortunately,
the time-varying covariates used to obtai
250 Unfortunately,
the true prevalence, quantitative levels,
251 Unfortunately,
the unambiguous identification of these m
252 Unfortunately,
the underlying physiological deficits in
253 Unfortunately,
the weak variation of electrical resistan
254 Unfortunately,
their exchange that can reveal their exot
255 Unfortunately,
their recycling is currently limited, and
256 Unfortunately,
their utility is compromised by significa
257 Unfortunately,
therapeutic iron chelators also have unde
258 MR is highly associated with graft loss, but
unfortunately there are few efficacious therapies to pre
259 Unfortunately there is no cure.
260 Unfortunately,
there are currently no effective antivira
261 Unfortunately,
there are relatively few compounds in exi
262 Unfortunately,
there are still a large number of patient
263 Unfortunately,
there are very few animal models of HTLV-
264 Unfortunately,
there exist serious issues such as limite
265 tedness and various environmental variables,
unfortunately,
there has been no unified answer to valid
266 Unfortunately,
there have been only a few attempts to cr
267 Unfortunately,
there is currently a tradeoff between acc
268 Unfortunately,
there is no available pharmacologic appro
269 Unfortunately,
there is no effective pharmacologic appro
270 Unfortunately these can only be solved for the simplest
271 Unfortunately these molecules cause a gastric enteropath
272 Unfortunately,
these cells also attack host normal tissu
273 Unfortunately,
these datasets often have small sample si
274 Unfortunately,
these high curvatures and complex forms a
275 Unfortunately,
these mechanisms are not adequately modul
276 Unfortunately,
these medications are associated with wei
277 Unfortunately,
these methods are limited to laboratory o
278 Unfortunately,
these trials have been designed without a
279 ed cells successfully remyelinate axons, but
unfortunately they do not migrate far and so remyelinate
280 Unfortunately,
this approach requires knowledge in advan
281 Unfortunately,
this approach suffers from several limita
282 Unfortunately,
this condition is not fulfilled in elasti
283 Unfortunately,
this is just the tip of the research wast
284 Unfortunately,
this method inherently requires fluoresce
285 Unfortunately,
this success has been tempered by uninten
286 Unfortunately,
tree ring analysis can be plagued by bias
287 Unfortunately,
unless combined with a bone marrow transp
288 Unfortunately,
up until now all methods for finding high
289 Unfortunately,
variant library expression platforms in m
290 Unfortunately,
vascular normalization is a difficult app
291 Unfortunately,
very limited information is available reg
292 Unfortunately,
vision and RGC loss are irreversible, and
293 Unfortunately,
wastewater contains biologically active,
294 Unfortunately,
wastewater often contains biologically ac
295 Unfortunately,
while many Palaeolithic sites contain lar
296 Unfortunately,
while the initial induction of these immu
297 ring visual functions in blind patients but,
unfortunately,
with still poor gains in visual acuity.
298 Unfortunately,
with these stimuli, many different mechan
299 Unfortunately,
with very little published data on the ep
300 stances in milk in order to raise profits is
unfortunately worldwide.