ライフサイエンスコーパス: unknown protein

1 ction from a protein of known function to an unknown protein.

2 crease the accuracy of the assignment of the unknown protein.

3 mal growth factor-related receptor]), and an unknown protein.

4 available protein spectra to match with the unknown protein.

5 amic, suggesting their stabilization by some unknown protein.

6 r1), a trypsin-like protein (Lltryp2) and an unknown protein.

7 psin like proteins (LuloChym1A and 2) and an unknown protein.

8 may interact with or be phosphorylated by an unknown protein.

9 rotein, NADH dehydrogenase subunit 2, and an unknown protein.

10 tion factor, epithiospecifier protein and an unknown protein.

11 ort system, (2) immunity, and (3) previously unknown proteins.

12 igned putative functions, whereas 123 encode unknown proteins.

13 ilies representing these 48% of structurally unknown proteins.

14 t to result from a prion form of one or more unknown proteins.

15 genes in Leishmania, of which 40% may encode unknown proteins.

16 for the automatic annotation of a testset of unknown proteins.

17 The main use is to predict the function of unknown proteins.

18 duced by BMP rather than amelogenin or other unknown proteins.

19 ify new functions for several unannotated or unknown proteins.

20 bers of apparently nonspecific contacts with unknown proteins.

21 ng both known ribosomal assembly factors and unknown proteins.

22 jor capsid proteins VP1 and VP2 and smaller, unknown proteins.

23 n data allows the prediction of function for unknown proteins.

24 e of ESTs encoding novel and/or functionally unknown proteins.

25 In the current study, we characterized this unknown protein and tested its potential targeting roles

26 isotope labeling, which impedes analysis of unknown proteins and complex mixtures and exponentially

27 Regions III and V bound unknown proteins and exerted strong enhancer-like activi

28 dentification of the biochemical function of unknown proteins and improves the quality of reconstruct

29 this response could invoke known as well as unknown proteins and pathways.

30 c stem cells to classify a set of previously unknown proteins, and validate our findings against a re

31 Two functional predictions for unknown proteins are made based on integrating other dat

32 However, capturing labile, unknown protein assemblies directly from cells remains a

33 listic framework for predicting functions of unknown proteins based on the functional similarity.

34 g pathway involves the phosphorylation of an unknown protein by polo-like kinase 1/Xenopus laevis pol

35 binding activity of DEF-A, we identified the unknown protein by using conventional purification metho

36 Finally, using in-line LC-MS, unknown proteins can be identified from solubilized Esch

37 Often functional clues of unknown proteins can be obtained by predicting small lig

38 functional analysis because the function of unknown proteins can be postulated on the basis of their

39 rithms, constitute a significant fraction of unknown protein-coding genes.

40 ngs provide novel insights into a previously unknown protein complex that can regulate EGFR traffic a

41 free methods for the discovery of previously unknown protein complexes in cryo electron tomograms.

42 robably consisting of xnf7 and several other unknown protein components.

43 by Plk1/Plx1-mediated phosphorylation of an unknown protein, correlates with the activation of the t

44 ensemble averaging" procedure to account for unknown protein costs.

45 ctor-2, Grb2-associated protein 2, and other unknown proteins could distinguish DCIS from IDC of the

46 contain a rich repertoire of both known and unknown protein-encoding and non-coding RNAs.

47 laments [7, 8], but it is plausible that yet-unknown proteins facilitate anchoring of the ER membrane

48 The RGMB structure reveals a previously unknown protein fold and a functionally important autoca

49 Here we show a previously unknown protein fold, and the design and interpretation

50 s of protein interfacial interactions within unknown proteins following appropriate calibration.

51 d is demonstrated for a peptide standard and unknown proteins from a yeast lysate using all 6118 poss

52 ntification and characterization of a priori unknown proteins from an Escherichia coli (E. coli) solu

53 rated in the bait toward a target residue of unknown proteins, here we genetically encode chemical cr

54 sequences is a common method for identifying unknown proteins; however, the processing of MSMS by cur

55 Sixteen HYPOXIA-RESPONSIVE UNKNOWN PROTEIN (HUP) genes, including four that are Ara

56 nd structural similarity with PMI15, another unknown protein in Arabidopsis that, when mutated, cause

57 the Hv channel VSD assembles with an as yet unknown protein in the cell membrane as a requirement fo

58 o model potential binding sites for known or unknown proteins in DNA sequences.

59 e predicted interactions for many previously unknown proteins in known pathways and complexes.

60 the potential importance of these previously unknown proteins in microbial metabolism.

61 quire specific interactions between CFTR and unknown proteins in the apical compartment of epithelial

62 fication of RanGAP1 in vitro and of multiple unknown proteins in vivo.

63 The screen yielded previously unknown proteins including one we named COPR1, for comod

64 Our data suggest previously unknown protein interfaces across Y complexes and to inn

65 An open reading frame coding for an unknown protein is identified in the promoter of IRXA2 o

66 co-occurrence data, the neighborhood around unknown proteins is quickly connected to well-characteri

67 to chemical labeling, as well as previously unknown protein isoforms including pSPs.

68 KCC1, which is directly phosphorylated by an unknown protein kinase in response to various secretagog

69 ated protein kinases (MAPKs), but also by an unknown protein kinase(s).

70 hrocyte invasion, while identifying numerous unknown proteins likely to be involved in invasion.

71 neurons by using a host of known and as yet unknown protein machinery.

72 mon poxvirus carries numerous genes encoding unknown proteins, many of which have low sequence comple

73 ccumulation, and uncover multiple previously unknown proteins modulated by short-term -N in green alg

74 Our results indicate that the previously unknown protein NPX1 acts as a negative regulator in pla

75 ht to be involved in membrane fusion, and an unknown protein of 40 kDa.

76 er microarray, we found that thrombin and an unknown protein of E. coli (protein X) formed a complex

77 so allow the identification of the remaining unknown proteins of this FMRP-associated mRNP as well as

78 rresponding to fibronectin, vitronectin, and unknown proteins, one of which was identical to the size

79 relevant Cys residues were sequestered by an unknown protein or that a significant portion of the Fep

80 istically 'unusual' in the composition of an unknown protein, or to automatically cluster proteins in

81 s a regulatory domain that interacts with an unknown protein partner to modulate the autokinase activ

82 A-IV interacts with lipids and possibly with unknown protein partners.

83 rast, HRD1 and HRD3 genes encoded previously unknown proteins predicted to be membrane bound.

84 ng methods for modeling the 3D structures of unknown protein-protein complexes.

85 rary will be useful to predict structures of unknown protein-protein interactions.

86 MDP-1 is most likely a phosphotyrosine in an unknown protein rather than a small sugar-based substrat

87 mall proline-rich superfamily, loricrin, and unknown proteins related to the desmoplakin family.

88 The most common method for determining an unknown protein's structural class is to perform expensi

89 st-genomic age, it is possible to predict an unknown protein's structural class using machine learnin

90 pathway and the O-linked glycosylation of an unknown protein(s) by UDP-N-acetylglucosaminyl transfera

91 at the SH2 domain is binding to a heretofore unknown protein(s) necessary for proper EGFR function.

92 l site can also bind NF-kappaB as well as an unknown protein(s) of approximately 40 kDa.

93 Kgamma, and induces polyubiquitination of an unknown protein(s) that associates with NEMO, likely by

94 in RING E3 ligase complex to ubiquitylate an unknown protein(s) to limit error-prone repair during V(

95 stitutive occupancy of a binding site for an unknown protein(s); however, we detect no protein-DNA in

96 s, has been successfully used to identify 52 unknown protein samples (seven different proteins) with

97 on at subpicomole levels and for identifying unknown proteins separated by 2-dimensional gel electrop

98 ical was suggested to take an H atom from an unknown protein source, most likely cysteine 141.

99 ingle template, inter-atomic distances of an unknown protein structure are assumed to be distributed

100 A relatively unknown protein structure motif forms stable isolated si

101 es that this method can determine previously unknown protein structures and here yields, to our knowl

102 tational methods can be used to both predict unknown protein structures and model ligand interactions

103 lex structures or direct de novo modeling of unknown protein structures.

104 The accumulation of unknown proteins, sucrose transport and cleavage enzymes

105 es, our new method reveals a large number of unknown proteins, supporting the notion that there are m

106 therefore postulate that HtrA may act on an unknown protein target that potentiates the activation o

107 We show that a previously unknown protein, termed as Charon, functions as a regula

108 onnection to IKK and SAPK/JNK), a previously unknown protein that directly interacts with NEMO/IKKgam

109 example of the identification of an a priori unknown protein that is not present in an annotated prot

110 This gene encodes a previously unknown protein that is predicted to function as a carbo

111 The TFF1 protein partner is a previously unknown protein that we have called TFIZ1 for trefoil fa

112 ic subunits: Dicer-2(DCR-2) and a previously unknown protein that we named R2D2.

113 lobiose and glucose include Lam81A and three unknown proteins that are homologous to aminopeptidases

114 scription factors, signaling components, and unknown proteins that are rapidly and robustly induced b

115 methyltransferase activity and on additional unknown proteins that bind to CARM1.

116 el-purified apomyoglobin and BSA, as well as unknown proteins that cofractionate with Tyl-virus-like

117 a: a mixture of known proteins, a mixture of unknown proteins that commonly contain sequence variatio

118 unctionally diverse assemblage of previously unknown proteins that regulate postsynaptic inhibition a

119 ogy of this element, we found binding of two unknown proteins that were antigenically distinct from G

120 aradigm to perform quantitative analysis of "unknown" proteins that differ in accurate mass.

121 gh both techniques were able to identify the unknown protein, the VHPLC method gave twice as many seq

122 llobiose include a xylanase (Xyl10A) and two unknown proteins, the C-terminal regions of which are ho

123 calization and the prediction of the role of unknown proteins, the confirmation of bioinformatic pred

124 the nucleus is accomplished by a previously unknown protein tyrosine phosphatase (PTP).

125 plex containing NALCN and a large previously unknown protein UNC-80.

126 We identified PhoX, and the previously unknown proteins UshA and CpdB as the major phosphatases

127 The in vivo importance of these unknown proteins was validated in invertebrate (fruit fl

128 one approach to characterizing functions of unknown proteins, we now present in GenProtEC some level

129 provide on the structural preferences of an unknown protein?" We have selected 20 different proteins

130 Many of these unknown proteins were abundant in both corn and prairie

131 , lipopolysaccharide biosynthesis, and other unknown proteins were confirmed for attenuation.

132 -like protein, a peptide transporter and two unknown proteins, which may represent components require

133 Here, we identify two previously unknown proteins, which we have named "TRP channel-assoc

134 include a mixture of well-characterized and unknown proteins whose biological roles and importance a

135 nes encoding human (h) Grb7 and a previously unknown protein with high homology to hGrb-IR and mGrb10

136 We assign function to unknown proteins with a probability representing the con

137 rendered their surface capable of detecting unknown proteins with cognizance not seen with conventio

138 eins for effectively predicting function for unknown proteins with high reliability.

139 acterization of both modified and unmodified unknown proteins with masses up to approximately 28 kDa.

140 e that the human genome codes for previously unknown proteins with unrelated functions that can augme