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1 the efficiency with which Env moved from the unliganded state.
2 ylated HIV-1 Env trimer in its uncleaved and unliganded state.
3 ut maintain the extended conformation in the unliganded state.
4 presents the first structure of HDAC8 in the unliganded state.
5 --> close" conformational equilibrium in the unliganded state.
6 s dynamic nucleocytoplasmic shuttling in the unliganded state.
7 ace (high-affinity conformation) even in the unliganded state.
8 +) complex with bound ADP-ribose, and in the unliganded state.
9 re potent repressors of transcription in the unliganded state.
10 f the extent of salt bridge formation in the unliganded state.
11 h SCP-2 being monomeric in both liganded and unliganded states.
12 or Asp markedly reduced dimerization in the unliganded state, albeit with apparent retention of the
14 nuclear magnetic resonance techniques in the unliganded state and in complex with beryllofluoride.
15 tibility to tryptic cleavage at Arg-8 in the unliganded state and in the pH dependence of peptide bin
16 age in any hydrogen bond interactions in the unliganded state and it donates a hydrogen bond to only
17 Env proteins are kinetically trapped in the unliganded state and require the drug to negotiate CD4-i
21 ith the introduced cysteines in the resting (unliganded) state and compared them with rates determine
22 in decreased gp120-gp41 association (in the unliganded state) and decreased chemokine receptor bindi
23 epressors to nuclear receptors occurs in the unliganded state, and can be stabilized by antagonists.
25 nooxygenase, stachydrine demethylase, in the unliganded state (at 1.6 A resolution) and in the produc
26 g cavity of CD1a is largely preserved in the unliganded state because of persistent electrostatic int
28 tein domains, is more stable than the native unliganded state by approximately 1 kcal/mol in this sys
29 ane envelope glycoprotein that stabilize the unliganded state by modulating the transitions from the
31 or to which the environment of Arg-8 in the unliganded state differs in monomers and dimers, is rele
33 ated form of EpsE in nucleotide-liganded and unliganded state has been determined, and reveals a two-
34 v to change conformation from the metastable unliganded state in response to the binding of ligands (
35 romoting assembly of the gating ring from an unliganded state in which the four subunits interact as
36 rimeric Env displayed on native HIV-1 in the unliganded state, in complex with the broadly neutralizi
37 the overall shape of ct-AChBP in the apo or unliganded state is similar to that of homologues with k
38 uct state with the intermediate state and an unliganded state of MurA, we propose that dissociation o
40 ciency virus (SIV) must be maintained in the unliganded state of the envelope glycoprotein trimer.
41 nce of agonist but can become trapped in the unliganded state of the receptor by prior washout of ago
42 stration of an effect of dimerization in the unliganded state on neurophysin's hormone-binding site,
44 istic insights into the metastability of the unliganded state, receptor-induced conformational change
45 Both TR homodimers and heterodimers in the unliganded state selectively associated with glutathione
46 d roughly 20-fold more rapid exchange in the unliganded state than regions of low diversity (outer do
48 tes HIV-1 entry by rearranging from a mature unliganded state, through receptor-bound intermediates,
49 gp120 and regulates Env transitions from the unliganded state to downstream conformations.IMPORTANCE
52 tential of the AF-1 activation domain in the unliganded state; upon ligand activation, a conformation
53 urophysin-II derivatives in the liganded and unliganded states, with the notable exception of the ext
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