ライフサイエンスコーパス: unmasking of

1 skeletal muscle; and (d) insulin causes the unmasking of a COOH-terminal antigenic epitope in skelet

2 ther amino acid permeases similarly involves unmasking of a cytosolic Art1-target region coupled to a

3 DMBT1 deletions, but at least one reflected unmasking of a germline DMBT1 deletion.

4 eonine, suggesting a mechanism involving the unmasking of a latent membrane localisation sequence in

5 hesis that regulatory potency is enhanced by unmasking of a ligand-binding site in the C-terminal CCP

6 These findings indicate that masking and unmasking of a lipid is central to the regulation of fer

7 Notch activation requires unmasking of a metalloprotease cleavage site remote from

8 multiple activation domains but also in the unmasking of a potent activation domain on E47/Pan1 that

9 Selective unmasking of a single hydroxyl group precedes solid-phas

10 ific N-terminal proteolytic cleavage and the unmasking of a tethered ligand.

11 n some macular diseases may be attributed to unmasking of AF rather than to increased fluorophores wi

12 condary hydroxyl in the two resulting diols, unmasking of an exocyclic methylene group at C-11, and s

13 signaling mechanism involves the proteolytic unmasking of an N-terminal receptor sequence that acts a

14 The unmasking of beta(1-3)-glucan also results in increased

15 n-sensing prodrug platform for the selective unmasking of bioactive agents in hypoxic cells.

16 The unmasking of bromodomains and activator recruitment, con

17 .5(D1790G) exhibits Ca(2+) insensitivity and unmasking of CaM regulation of inactivation gating.

18 (1) resulting in increased longevity and the unmasking of cancer predisposition, frequently hepatocel

19 ccurred degradation of total chlorophyll and unmasking of carotenoids from 31st days after anthesis.

20 This unmasking of catalytic and regulatory potential of the L

21 Conversely spontaneous "unmasking" of cell wall lipids may promote airway inflam

22 Trypsin concentration and the unmasking of cleavage sites in proteins play important r

23 out disulfide reduction by (i) enhancing the unmasking of cleavage sites through elevated reaction te

24 nformational change in SCAP, detected by the unmasking of closely spaced trypsin cleavage sites.

25 Unmasking of collagen fibers was most predictive of abno

26 .g., some DMBT1 homozygous deletions reflect unmasking of constitutional deletion polymorphisms by 10

27 ith 10q loss, but all 10 deletions reflected unmasking of constitutional hemizygous deletions.

28 te specificities compatible with proteolytic unmasking of cryptic CendR motifs, the strategy describe

29 Here we report that unmasking of cryptotopes by unfolding whole cytomegalovi

30 This approach utilizes sequential unmasking of cysteine residues with orthogonal protectio

31 n by its myristoyl group, and Ca2+-dependent unmasking of different residues, may explain how each fa

32 staining is not caused by the retraction or unmasking of dynein upon detachment.

33 the truncated TrkB receptor did not involve unmasking of endogenous TrkC signaling.

34 Pharmacologic unmasking of epigenetic silencing in breast cancer cells

35 mechanism for such rapid changes may be the unmasking of existing divergent and convergent thalamoco

36 The kinetic unmasking of inhibited binding reflected in the increase

37 We propose that there is an unmasking of inhibitory mechanisms or a reduction in des

38 to show how the plasticity may relate to the unmasking of latent bulbospinal respiratory connections

39 suggesting that cortical reorganization or "unmasking" of latent pathways can contribute to function

40 ially highly dynamic mechanisms such as the 'unmasking' of latent pathways.

41 the Leu3-dd phenotype) that cause permanent unmasking of Leu3p.

42 ecular association in the monomer results in unmasking of ligand binding sites and a significant conf

43 Under the drug, the strength of spatial unmasking of midbrain neurons approximated that of audit

44 egative mutant S6 is cytoplasmic, due to the unmasking of NES.

45 We report that the immediate unmasking of new receptive fields after acute nerve inju

46 gesting that the vagus nerve is required for unmasking of NK-2 responses.

47 ctral-domain OCT and may be explained by the unmasking of normal background RPE AF.

48 ing suggests that it is likely caused by the unmasking of normally suppressed spatially tuned excitat

49 ed prerestorative satiety mechanism, and the unmasking of other opioid-mediated signalling mechanisms

50 changes in the cerebral cortex, probably via unmasking of pre-existent connections.

51 wth of new connections), instead implicating unmasking of preexisting connections as the underlying n

52 an those without eosinophilia, suggesting an unmasking of preexisting eosinophilia as sepsis resolves

53 ractions are counterbalanced, leading to the unmasking of preferences for conformations that resemble

54 entiation of presynaptic function, including unmasking of previously "silent" synapses.

55 kg)-precipitated withdrawal hyperalgesia and unmasking of prominent opioid analgesia.

56 an organism to the risks associated with the unmasking of recessive mutations.

57 NO synthase inhibitor, blocked 5-HT-induced unmasking of SP responses (n = 10 of 10 neurones).

58 agonist, completely blocked the 5-HT-induced unmasking of SP responses (n = 10 of 10 neurones).

59 5-HT-induced unmasking of SP responses was dose dependent (EC50 = 14

60 5-HT-induced unmasking of SP responses was maximal within 5 min.

61 ediated elevation of [Ca2+]i is required for unmasking of SP responses.

62 the spermatids, where it is involved in the unmasking of stored SPDS mRNAs, leading to substantial s

63 lts from changes in synaptic strength and/or unmasking of subthreshold intermodal connections.

64 ryptic intragenic variation and (ii) enabled unmasking of such variation due to DNA replicative slipp

65 e of POP repair to prevent the postoperative unmasking of SUI in women who do not have SUI preoperati

66 onal evidence that such RIAM-mediated steric unmasking of talin triggers integrin activation.

67 fficking regulation that we term "controlled unmasking of targeting elements" (CUTE).

68 in mammalian cells suggests that masking and unmasking of the activation domain occur without the par

69 21st century, determined by the rate of the unmasking of the aerosol cooling effect by air pollution

70 ilization and by proteolysis correlates with unmasking of the alpha(M)beta2-binding site in the D-dom

71 The translocation also results in an unmasking of the ARF COOH terminus, suggesting that redi

72 restoration of the choroidal blood flow and unmasking of the big choroidal vessels.

73 Protection of the C37 carbonol and selective unmasking of the C44 carbonol completed our second gener

74 s in the C-terminal domain did not result in unmasking of the catalytic domain.

75 the phenols, O-sulfation, and photochemical unmasking of the cyclopropenone moiety.

76 ncluding domains 1 and 2, suggesting that an unmasking of the DNA binding surface may be a preconditi

77 Unmasking of the DO-1 epitope via dephosphorylation occu

78 removing the potential for metabolism-based unmasking of the embedded aniline.

79 aving greyish, granular, depigmented fundus, unmasking of the large choroidal vessels and optic atrop

80 part of the morphological substrate for the unmasking of the latent crossed phrenic pathway which me

81 terminus of full-length ARTEMIS resulted in unmasking of the N terminus and in increased ARTEMIS act

82 Hydrogenolytic unmasking of the nitroso acetal tosylate 17 containing t

83 -phase synthesis support following selective unmasking of the nucleophile incorporated in these phosp

84 umor suppressor genes based on pharmacologic unmasking of the promoter region and detection of re-exp

85 umor suppressor genes based on pharmacologic unmasking of the promoter region and detection of reexpr

86 membrane-associated factor that promotes the unmasking of the rab11-binding site in rab11BP.

87 Finally, the efficiency of the photochemical unmasking of the support bound alkylamine on a 1 mumole

88 The unmasking of the Tau-12 epitope in more mature 5A6-posit

89 ynamics may be responsible for the apparent "unmasking" of the backbone resonances in the presence of

90 s efficiently with minimal toxicity, because unmasking of their hydrophobic domains selectively occur

91 xes are excellent reagents for the effective unmasking of thiazolidine, enabling its complete removal

92 ormation through a phosphorylation-dependent unmasking of this region.

93 Unmasking of this site serves as a molecular switch that

94 rminal mitochondrial targeting sequence, the unmasking of which occurs in the hereditary calcium oxal