ライフサイエンスコーパス: unmetabolized

1 hat this is due to initial "trapping" of the unmetabolized (11)C-DASB compound in the lung, a major 5

2 The unmetabolized (11)C-DASB fraction was measured in arteri

3 We noted that the percentage of unmetabolized (11)C-DASB is often lower at 2 min after i

4 Oral sertraline raised the 2-min unmetabolized (11)C-DASB percentage.

5 rs contributes to the lower initial level of unmetabolized (11)C-DASB, we examined the effects of ser

6 on (1% +/- 2%) and complete backdiffusion of unmetabolized (11)C-lactate into the vasculature (28% +/

7 be preferred over SUV or SKA-S when a large unmetabolized (18)F-FDG fraction is expected and 1-3 fie

8 ion, 37% of plasma radioactivity represented unmetabolized (18)F-GE-179.

9 The percentage of unmetabolized (18)F-T807 in plasma followed a single exp

10 Results: The percentage of unmetabolized (18)F-T807 in plasma followed a single exp

11 sma HPLC revealed two peaks corresponding to unmetabolized [18F]-FPCIT and a polar metabolite.

12 Unmetabolized [18F]FLT accounted for 71.54 +/- 1.50% of

13 ese two enzymes and the urinary excretion of unmetabolized and Phase II conjugates of the two HAAs Me

14 d 2-tissue-compartment models using unbound, unmetabolized arterial 2FA concentration as the input fu

15 d a single peak that corresponded on HPLC to unmetabolized authentic FPCT.

16 d to be 94%) and cholehepatic cycling of the unmetabolized bile acids.

17 the isoquinoline alkaloids excreted in urine unmetabolized can be detected.

18 dase activation but could synergize with the unmetabolized dioctanoylglycerol to activate superoxide

19 tumor lines, most of the [3H]retinol remains unmetabolized during the 24-h culture period; MDA-MB-468

20 se synthetic ligands such as Wy-14,643 or by unmetabolized endogenous ligands resulting from the disr

21 enous HO-1 protein and an increase (167%) in unmetabolized exogenous heme in HMEC-1 cells.

22 Measurement of levels of endogenous unmetabolized F2-isoprostanes has proven to be a valuabl

23 llections offers an advantage over measuring unmetabolized F2-isoprostanes, e.g. in a plasma sample,

24 her fortification elevated concentrations of unmetabolized FA in plasma and whether this form of the

25 At 60 min after injection, unmetabolized FIAU radioactivity in blood and urine samp

26 We explored concentrations of fasting unmetabolized folic acid (UFA) in the circulation of chi

27 ht to determine breast-milk total folate and unmetabolized folic acid (UMFA) contents and their relat

28 and cord blood concentrations of folate and unmetabolized folic acid (UMFA) in a cohort of pregnant

29 ults are also consistent with the reports of unmetabolized folic acid in plasma and urine.

30 These results indicate unmetabolized folic acid in plasma in most of this elder

31 measure the basal (fasted) concentrations of unmetabolized folic acid in the plasma of an elderly pop

32 nd cognitive test performance to circulating unmetabolized folic acid or 5-methyltetrahydrofolate (5M

33 Unmetabolized folic acid was detected in 94.1% of the co

34 Circulating unmetabolized folic acid was detected in approximately 3

35 Little unmetabolized folic acid was excreted in urine.

36 d with the absence of detectable circulating unmetabolized folic acid was related to lower cognitive

37 acid intakes, perhaps as a direct result of unmetabolized folic acid, which does not occur naturally

38 te, red blood cell folate, homocysteine, and unmetabolized folic acid.

39 ations of naturally occurring folates and of unmetabolized folic acid.

40 y explain reports of systemic circulation of unmetabolized folic acid.

41 blood analysis found >90% of the activity in unmetabolized form.

42 igned to 4-hydroxy-2-nonenoic acid (HNA) and unmetabolized HNE, respectively.

43 Peak IV was due to unmetabolized HNE.

44 in green tea, is unclear because it appears unmetabolized in low concentrations in plasma but is not

45 ) by endogenous ligands in liver that remain unmetabolized in the absence of Acox1.

46 Ralpha-regulated genes by biological ligands unmetabolized in the absence of AOX.

47 99mTc-duramycin is completely unmetabolized in vivo, and the intact agent is recovered

48 odies suggests that the higher percentage of unmetabolized NMP in larvae relative to adults may be du

49 unique mechanism of antiviral action by the unmetabolized nucleoside analogue.

50 tracer in the brain stem was in the form of unmetabolized parent compound, but plasma showed rapid p

51 simple, rapid method for the measurement of unmetabolized plasma FA in epidemiologic studies.

52 the dose, whereas the total amount of PhIP [unmetabolized plus acid-labile conjugate(s)] in the 0-12

53 iation between NAT2 activity and the levels (unmetabolized plus acid-labile conjugates) of MeIQx or P

54 higher CYP1A2 activity, whereas total PhIP (unmetabolized plus conjugated) in urine showed no associ

55 r acid treatment, the total amount of MelQx (unmetabolized plus the N2-glucuronide and sulfamate meta

56 sion analyses showed that lower total MeIQx (unmetabolized plus the N2-glucuronide and sulfamate meta

57 Compound I gave the highest level of unmetabolized radioligand present in blood up to 45 min

58 analyzed for total radioactivity and percent unmetabolized radioligand.

59 Unmetabolized serum folic acid (UMFA) has been detected

60 Accordingly, unmetabolized substrate concentrations are higher within

61 Deficiency of ACOX1 results in unmetabolized substrates of this enzyme that function as

62 than 50% of the radioactivity was recovered unmetabolized, whereas in wild-type mice nearly all of t