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1 of stress (rendering aggression risky and/or unnecessary).
2 agments, for site-directed mutagenesis it is unnecessary.
3 reshold currents or synaptic facilitation is unnecessary.
4 ge change in albuminuria from baseline seems unnecessary.
5 ose, thus indicating that multiple doses are unnecessary.
6 ns, since time-consuming culturing steps are unnecessary.
7 oups directly, rendering community detection unnecessary.
8 e GAS detection, making culture confirmation unnecessary.
9 g wakefulness, even when hypocapnia makes it unnecessary.
10 d dose has limited benefit and appears to be unnecessary.
11 on the use of repackaged bevacizumab may be unnecessary.
12 ining anti-HCV therapy is discriminatory and unnecessary.
13 y was confirmed and intestinal biopsies were unnecessary.
14 be computationally prohibitive and is often unnecessary.
15 king preoperative common duct investigations unnecessary.
16 ime of conception are likely unwarranted and unnecessary.
17 lth regarded specialist follow-up as largely unnecessary.
18 employ tools, using them even when they are unnecessary.
19 (HBED), making subsequent purification steps unnecessary.
20 licitly, thus rendering such transformations unnecessary.
21 ll-cohort estimates were similar, making IPW unnecessary.
22 sk and hopefully make implantation of an ICD unnecessary.
23 n in controls, where getting off the mat was unnecessary.
26 ate aRT might reduce overtreatment, decrease unnecessary adverse effects, and reduce risk of CR in th
27 f random Raman lasing renders directionality unnecessary, allowing for the detection and identificati
28 stronger recognition tag, the E-tags become unnecessary and ClpX's preference for the complex over M
30 as dichotomous even when dichotomization is unnecessary and misleading, as in inferences based on wh
31 sion on when to start antiretroviral therapy unnecessary and that, instead, efforts should be aimed a
32 ly stable patients was that a sternotomy was unnecessary and the cardiac injury, if present, had seal
34 on by CMR resulted in a lower probability of unnecessary angiography within 12 months than NICE guide
35 1%) in the MPS group; adjusted odds ratio of unnecessary angiography: CMR group vs NICE guidelines gr
36 nosis of UTI were common and associated with unnecessary antibiotic exposure and missed STI diagnoses
38 l infection, many children worldwide receive unnecessary antibiotic treatment, while bacterial infect
39 hospitals is 2.9%, potentially resulting in unnecessary antibiotic use and excessive therapy costs.
40 ibiotics with the highest risks and reducing unnecessary antibiotic use are important strategies for
41 uses might improve clinical care by reducing unnecessary antibiotic use, shortening length of hospita
45 nd Clostridium difficile infections, halting unnecessary antimicrobial use has become one of the larg
48 cne by primary care clinicians may eliminate unnecessary appointments, reduce wait time for treatment
51 D1 axis maintains homeostasis by suppressing unnecessary autophagic breakdown of cellular components,
52 tam antibiotics is common and often leads to unnecessary avoidance in patients who could tolerate the
53 The exoribonuclease activity of RNase BN is unnecessary because all its action on 6S RNA is due to e
54 screening for extensive hip osteonecrosis is unnecessary because their risk is low and lesions tend t
56 Due to its 100 % NPV, Simtomax could reduce unnecessary biopsies by 66 % if only those with a positi
58 arm clearly exists, including a high rate of unnecessary biopsies, possibly resulting in cosmetic or,
62 rinary testing for T2:ERG and PCA3 can avert unnecessary biopsy while retaining robust sensitivity fo
64 ] and platelet count), and its use may avoid unnecessary blood product transfusion in patients with c
65 ric MR imaging may have potentially obviated unnecessary breast biopsies in six of eight lesions (P =
66 atients with high PSA levels have to undergo unnecessary but physically painful and expensive procedu
67 se of the hierarchic data structure to avoid unnecessary calculation, especially for collision detect
71 ncludes, sperm are streamlined by discarding unnecessary cellular components into cellular wastebags
77 individuals required at least one additional unnecessary computed tomography scan or magnetic resonan
79 enclature for atopic dermatitis (AD) creates unnecessary confusion for patients, healthcare providers
80 nders hospital improvement efforts by adding unnecessary confusion to the already complex arena of pe
82 sed healthcare costs, longer hospital stays, unnecessary consultations, and inappropriate use of anti
83 of this policy commitment would also render unnecessary continued substantial expenditure on fossil
84 The primary end point was protocol-defined unnecessary coronary angiography (normal fractional flow
86 cols that incorporate these DIs may decrease unnecessary costs and radiation exposure in the dispropo
87 SNP-CROP maximizes data usage by eliminating unnecessary data culling due to imposed read-length unif
88 vision will prevent hundreds of millions of unnecessary deaths during the remainder of this century
89 relaxation, poor ventilator synchronization, unnecessary deep sedation, agitation, and an overall opt
90 quires the avoidance of pain, agitation, and unnecessary deep sedation, but these outcomes are challe
96 ood functional outcome remains uncertain and unnecessary delays to treatment may be faced while monit
97 in 36% of all referred patients), and avoids unnecessary desensitizations in nonhypersensitive patien
99 mpiric diet with few food triggers, avoiding unnecessary dietary restrictions, saving endoscopies, an
102 lly avoidable risk factors continue to cause unnecessary disability and premature death in older peop
106 ack and believes that this tool may decrease unnecessary download requests, while still facilitating
108 (eg, pulmonary visit) or when follow-up was unnecessary (eg, in patients with a terminal illness).
110 gorithm was similar and would have spared 19 unnecessary esophagectomies and 16 explorative laparotom
113 inician and radiologist leads to innumerable unnecessary examinations in the developed world, includi
114 ss," and "burnout"), and the health system ("unnecessary, excessive, and inefficient resource utiliza
115 elanoma improves early detection and reduces unnecessary excisions; however, a cost analysis of this
121 %] in PR peer review ), such as recommending unnecessary follow-up imaging or radiation exposure in p
122 g conjugates concluded that drug release was unnecessary for activity, highlighting the importance of
123 structures, lead to over fit models, and are unnecessary for an efficient, accurate predictive model
128 In light of recent observations that Myc is unnecessary for long-term hepatocyte proliferation, we h
130 However, such lifelong surveillance may be unnecessary for most patients, thereby contributing to o
134 Correction for dead time was found to be unnecessary for small-animal experiments, whereas propag
135 also show that a high electrolyte modulus is unnecessary for stable electrodeposition of lithium.
137 esults indicated that nontreponemal assay is unnecessary for syphilis diagnosis but can be recommende
139 hese results indicate that Hcrt signaling is unnecessary for the activation of Hcrt, HA, or ACh wake-
146 rity, there is the additional need to reduce unnecessary healthcare costs and radiation exposure.
148 nts, having a medical home, and avoidance of unnecessary hospitalization), and a social outcome (havi
150 ulitis misdiagnosis leads to 50000 to 130000 unnecessary hospitalizations and $195 million to $515 mi
158 often suffer from philosopher's disease: the unnecessary, inappropriate, theoretically driven explana
159 s or with an indication that prophylaxis was unnecessary increased from approximately 40% in 2005 to
161 les with a self-limiting response to prevent unnecessary inflammatory responses harmful to the organi
162 Use of the Bazett correction may result in unnecessary interruptions in ATO therapy, and alternativ
163 nature of these events is important to avoid unnecessary intervention, including the cessation of a p
164 ant women, leading to emotional distress and unnecessary interventions, including termination of preg
173 ports, and because hardware modification was unnecessary, it was convenient to frequently switch amon
175 p, there were 56 (6.7%) deaths and 29 (3.5%) unnecessary laparotomies, whereas in the latter NOM grou
176 iampullary cancer, but many patients undergo unnecessary laparotomy because tumours can be understage
182 agnetic resonance imaging and 39 required an unnecessary liver biopsy according to the recall policy.
184 timated by unsupervised training which makes unnecessary manually curated preparation of training set
185 essed (blood pressure control, discontinuing unnecessary medications such as aspirin or nonsteroidal
187 markers can therefore potentially help avoid unnecessary morbidity from high-dose corticosteroid ther
190 icantly reduced fouling, resulting in either unnecessary or approximately 10-15 times shorter and les
191 ic pathway by which eukaryotic cells deliver unnecessary or damaged cytoplasmic material to the vacuo
193 roperly with a risk of patient harm, costly, unnecessary or inappropriate investigations, or delayed
196 nalysis of discarded kidneys to determine if unnecessary organ discard was still occurring since the
197 measles cases and vaccine reactions to avoid unnecessary outbreak response measures such as case isol
199 des 2, beyond simple isolation, proved to be unnecessary owing to the impurity rejection afforded by
200 the absence of results from clinical trials, unnecessary oxygen delivery should be avoided in critica
201 the absence of results from clinical trials, unnecessary oxygen delivery should be avoided in ventila
202 : Despite suggestions of potential harm from unnecessary oxygen therapy, critically ill patients spen
203 men, -4 days for women), which was driven by unnecessary pancreatic surgeries associated with false-p
204 tremity cellulitis is common and may lead to unnecessary patient morbidity and considerable health ca
205 tremity cellulitis is common and may lead to unnecessary patient morbidity and considerable health ca
207 critically, typical carpet cloaks introduce unnecessary phase shifts in the reflected light, making
213 neal LN dissection revealed a high number of unnecessary procedures, but patients with positive LN ha
215 al due to the high rate of overdiagnosis and unnecessary prostate biopsies, despite evidence that it
216 prostate cancer are undermined by harms from unnecessary prostate biopsy and overdiagnosis of indolen
219 compared with administration of lower doses; unnecessary radiation exposure can be avoided by adminis
221 scrotal lesions and consequently can reduce unnecessary radical surgical procedures in these patient
222 ify risk factors and strategies for reducing unnecessary readmissions among this patient population.
223 uality improvement interventions that reduce unnecessary readmissions, even if the rates of transplan
225 eview process, editors can potentially avoid unnecessary rejections, identify key areas for improveme
227 ons targeting infected animals might lead to unnecessary removal of young animals that carry pathogen
230 Using this information, we identified the unnecessary resistance marker NeoR to be a highly transc
232 y in screening out low risk individuals from unnecessary restrictive interventions; very low positive
235 h, minimizing regulatory burden-particularly unnecessary, self-imposed burden-in the ACUP is particul
236 dless of its temporal position, resulting in unnecessary sequence errors, that they later try to corr
237 tiemetic overuse is prevalent and results in unnecessary spending associated with systemic chemothera
240 upport tool (CDST) to decrease the number of unnecessary stool cultures (STCUL), ova/parasite (O&P) e
244 real-world effectiveness of PET in avoiding unnecessary surgery for newly diagnosed patients with no
249 sion procedures, which expose the patient to unnecessary surgical procedures and inappropriate antibi
251 Their intervention significantly decreased unnecessary test orders and saved their laboratory over
252 tal information system (HIS) alerts to deter unnecessary test orders for ovum and parasite (O&P) exam
253 line, estimate expenditures from potentially unnecessary testing, and identify patient and health car
254 n of adaptive testing strategies that reduce unnecessary testing, while ensuring that patient deterio
260 eached clinical significance, while avoiding unnecessary tests and surgery in patients with benign no
262 ), including faster detection rates, reduces unnecessary therapy but permits therapy for ventricular
264 new paradigm for regeneration in which it is unnecessary to invoke special damage-resistant cell type
265 ailable, it is computationally expensive and unnecessary to study combinatorial patterns of all modif
270 ervices, redundancy of specialist attention, unnecessary travel), empowerment for health (self-preser
271 diagnosed as past or not syphilis, avoiding unnecessary treatment compared with other POC tests.
273 of Xpert, and the hypothetical reductions in unnecessary treatment, contact investigation, and housin
276 uish PTNFL from typical FL in order to avoid unnecessary treatment; however, this distinction relies
277 ertainty range [UR]: 0, 1.3) and generate 18 unnecessary treatments (95% UR: 10, 29) per 1,000 indivi
278 esulting in a median ratio of 38 incremental unnecessary treatments added by Ultra per incremental de
280 deaths averted, and the projected number of unnecessary treatments generated per TB death averted, i
281 omes were the projected number of additional unnecessary treatments generated, the projected number o
282 er absolute benefit-this ratio improved to 7 unnecessary treatments per TB death averted (95% UR: 2,
283 , this ratio was much less favorable, at 372 unnecessary treatments per TB death averted (95% UR: 75,
284 per bound), although the projected number of unnecessary treatments using Xpert Ultra was lower (with
287 ed as a triage test might allow men to avoid unnecessary TRUS-biopsy and improve diagnostic accuracy.
288 he need for other diagnostic tests, reducing unnecessary use of antibiotics, and leading to a reducti
290 n improve clinical outcomes while minimizing unnecessary use of broad-spectrum antibiotics, including
291 mpliance with the protocol, and avoiding the unnecessary use of intravenous and urinary tract cathete
293 radiograph after this common procedure is an unnecessary use of resources and may delay resuscitation
294 ow that this preprocessing approach leads to unnecessary variability in peak quantifications that adv
296 tion of preschool children from experiencing unnecessary VI and associated developmental delays.
297 proportion of individuals from experiencing unnecessary vision loss and blindness, decrease associat
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