ライフサイエンスコーパス: unravel

1 impact of these alterations are still being unraveled.

2 es to catalyze reactions has yet to be fully unraveled.

3 s of people, but its mechanisms remain to be unraveled.

4 RNA-binding proteins RsmA, RsmE and RsmI, is unraveled.

5 ether with partially oxidized Cu species was unraveled.

6 mplex electrochemical behavior of ZIFs to be unraveled.

7 ffects the chemical reaction dynamics can be unravelled.

8 e of Molecular Cell, Gutierrez et al. (2017) unravel a bacterial survival strategy that they term "de

9 Here, we unravel a highly devolved mechanism for recruitment of G

10 ic neuronal network manipulation promises to unravel a long-standing mystery in neuroscience: how doe

11 Our results unravel a mechanism likely involved in regulation of man

12 tical intracellular target for celastrol and unravel a mechanism of Nur77-dependent clearance of infl

13 Here, the authors unravel a mechanism through which EGF stimulation induce

14 II in cells and with the isolated enzyme and unravel a mode of RNA Pol II stalling that is due to alk

15 yte ability to protect synapses, our results unravel a new mechanism underlying the synaptotoxic acti

16 Our results unravel a new role of DNGR-1 in regulating vascular infl

17 Our results unravel a new role of Foxg1 in promoting OF closure prov

18 Overall, our data unravel a novel mechanism by which the MAPK signaling ne

19 Our studies unravel a novel mechanism regulating platelet activation

20 Our data unravel a poorly understood aspect of the cellular respo

21 To unravel a potential role of SPA proteins in COP1 nucleoc

22 These results unravel a previously unidentified link between O-GlcNAcy

23 Advances in structural biology unravel a rich repertoire of molecular mechanisms for en

24 Our data unravel a role for Plexin-B1 as a ligand and Sema4A as a

25 Here, we unravel a unique function of astrocyte elevated gene-1(A

26 be tuned by the external gate electrode and unravel a variety of electrostatic interactions in high-

27 employed to accurately recover, explain and unravel a wide variety of experimental data obtained dur

28 Furthermore, our data unraveled a nonuniform distribution of VGLUT3 in synapti

29 Altogether, these data unraveled a previously unknown link between an imbalance

30 atin immunoprecipitation sequencing analyses unraveled a transcriptional reduction of the transcripti

31 l-Co(III) enolate intermediates is provided, unraveling a carboxylate-assisted formation of aryl-Co(I

32 receptor binding regulates Kappa expression, unraveling a new mechanism mediating the well-establishe

33 Our work unravels a complex nicotine-stress bidirectional interpl

34 It also unravels a new functional role for cocaine-induced extra

35 Collectively, our study unravels a novel immunoregulatory mechanism of NAD(+) th

36 This study unravels a prominent role for the CD16-dependent NK cell

37 d cell fate change in postnatal skeleton and unravels a regulatory mechanism underlying this phenomen

38 ilient cooperators can permanently stabilize unravelling among a majority of rational players.

39 These findings unravel an additional layer of control in the expression

40 These results unravel an inhibitory circuit of possible relevance in p

41 These findings unravel an unexpected regulatory concept executed by coi

42 tein Tau in regulating synapse numbers, thus unravelling an important cellular requirement of normal

43 This study unravels an anti-metastatic role of AKT1 in the NSCLC ce

44 formation and therefore has the potential to unravel and gain an in-depth understanding of the key mo

45 moregulatory cold defense have been recently unraveled and could in theory be exploited to reduce ene

46 The remaining transcript is selectively unraveled and degraded.

47 Our findings unravel at the genome-wide level, the unique adaptive di

48 vides unprecedented opportunities to further unravel bacterial biodiversity and its worldwide role fr

49 idine cytotoxicity, providing a paradigm for unraveling bacterial mechanisms in drug metabolism.

50 To unravel biological uptake mechanisms of europium in A. c

51 tion of ASD subjects based on endophenotypes unraveled biologically relevant pathway disruption and r

52 level, combined with computational models to unravel both the interactions between phages and how ind

53 directional phonon suppression function, to unravel boundary-dominated heat transport in unprecedent

54 thylsiloxane (oDMSi) or alkyl side chains is unraveled by combining experimental and theoretical appr

55 ar pockets, and solvent molecules is further unraveled by explicit solvent molecular dynamics simulat

56 with the SNARE bundle that hindered v-SNARE unraveling by Cpx, thus compromising clamping.

57 tial recognition element of Abeta, have been unravelled by STD-NMR spectroscopy methods in solution.

58 een two biological conditions are crucial to unravel causalities behind phenotypes of interest.

59 dem MS may render this the key technology to unravel complex glycomes.

60 Next-generation sequencing of melanomas has unraveled critical driver genes and genomic abnormalitie

61 ulations that, in the past few decades, have unraveled crucial aspects of crystal nucleation in liqui

62 we provide a set of tools to help scientists unravel details of Mvarphi signaling.

63 We unravel details of the circuit mechanisms behind these p

64 nomonitoring, transcriptomics is starting to unravel diagnostic and prognostic signatures that strati

65 Additionally, we use calculations to unravel differences in energetics, structures and reacti

66 Together, our results unravel differences in subcellular localization and abil

67 of physicochemical and molecular indexes to unravel differential response of nine commercial wheat c

68 In silico and in vivo expression analyses unraveled differential accumulation of tRFs in Arabidops

69 This study unraveled differentially expressed novel biomarkers of i

70 potential future outcomes are progressively unraveled during multistep decision making.

71 spectroscopy can provide key information to unravel dynamic details of photo-functional molecules.

72 tial target for disease therapy and tool for unraveling early events in the onset of polyQ diseases.

73 regulatory mechanisms of transcriptomics and unraveled essential molecular biomarkers in osteosarcoma

74 Bdp1 and Pol II factors TFIIA and TFIIF, and unravels essential interactions with DNA and with the up

75 rs behave as resilient cooperators who avoid unravelling even at significant cost to themselves.

76 In sum, our results unravel evi1-pAKT as a novel molecular pathway that, in

77 g embryogenesis is of crucial importance for unravelling evolutionary, molecular and cellular mechani

78 evels; with excess, the helix is ejected and unravels, exposing a hydrophobic patch, which then serve

79 ssociated with partial surface reduction, as unravelled from chemical titration and electron energy-l

80 s data is becoming increasingly important to unravel functional mechanisms of complex diseases.

81 esent a series of MD simulations designed to unravel GB migration phenomena and set it in a GB migrat

82 proteomics of archaea that holds promise to unravel gene function.

83 ations and cell-to-cell variability can help unraveling genotype-phenotype relationships.

84 Unraveling gray matter degeneration is critical for deve

85 eloped a WAFEX-guided principal analysis and unraveled how phosphorylation destabilizes this highly c

86 Thus, unraveling how molecular tools are recruited in differen

87 coordinated starch and fructan synthesis and unraveling how plants allocate photosynthates and priori

88 By unravelling how ABQs mediate their activities, features

89 ce signalling within plants is important for unravelling how plants coordinate physiological response

90 d analysis of high-dimensional data can thus unravel immune alterations predisposing to complex infla

91 least squares regression modelling can help unravel interactions to identify groups of compounds tha

92 e-cell transcriptomics are ideally placed to unravel intratumoral heterogeneity and selective resista

93 n sporadic forms of BRAF-mutant GIST to help unravel its pathogenesis and therapeutic response to nov

94 standing of the human brain is essential for unraveling its functional architecture, yet current refe

95 quitination in these events is the basis for unraveling its precise role in health and disease.

96 such as Hirschsprung's disease will rely on unravelling its pathogenesis through genetics and the de

97 PC gene and lincRNA co-expression networks, unraveling key biological processes where lincRNAs might

98 Importantly, we unraveled large-scale changes in mRNA alternative splici

99 Our model further unravels long-range contacts depending on co-factors rec

100 urface hydroxyls on oxide surfaces is key to unraveling many physical and chemical processes, yet the

101 To unravel mechanisms of p53-mediated tumor suppression, wh

102 num accessions upon A. solani inoculation to unravel metabolic dynamics during different stages of di

103 d, recalcitrant lipid biomarkers are used to unravel microbial processes in the geological past.

104 rained dynamics" (QCGD) simulation method to unravel microstructural evolution of polycrystalline Al

105 ecific geochemical parameters can be used to unravel mixed metabolic signals in complex communities,

106 or without T. gondii infection, in order to unravel molecular factors directing robust and rapid ear

107 that provide unprecedented opportunities to unravel molecular heterogeneity of biological processes.

108 This technique permits us to unravel molecular-scale perturbations of lipid layers at

109 derstanding of this complex arrhythmia while unraveling more knowledge gaps and inadequacies of curre

110 ncentrate on remaining pedigrees in which to unravel new diabetes genes.

111 e powerful tools that are being exploited to unravel new functions with therapeutic advantage.

112 nt papers by Telerman et al. and Yang et al. unravel new molecular landscapes within the dermal papil

113 ight signaling pathways, recent studies have unraveled new functions of PIFs in integrating multiple

114 come the object of further research aimed at unraveling new diabetes genes.

115 This study unravels new strategies for using small bioactive molecu

116 Collectively, our results unravel novel complexities in the involvement and regula

117 Here, we unraveled novel functional facets of PknG during latency

118 steps are attributable to the formation and unraveling of conformational entanglements from newly in

119 gnal and provide a structural picture of the unraveling of parkin's ubiquitin ligase potential.

120 Cpx's interaction with the v-SNARE promotes unraveling of the v-SNARE off the core SNARE bundle.

121 Unravelling of disulfide linkage patterns is a crucial p

122 Auditory Cortex (ACx) have been difficult to unravel partly due to our assumption that it is organize

123 ased gene regulation has made it possible to unravel pathomechanisms, enabling the design of new ther

124 s from taxonomically distant species, it can unravel plant adulteration issues.

125 at are specific to hematopoietic cells, thus unraveling potential regulators of erythroid translation

126 New research has unraveled previously unknown downstream neural circuit c

127 oves earlier for several days; however, this unravelling process stabilizes after roughly one week.

128 d experimental and computational study helps unravel relative hMSC PS and HC effects on human cardiac

129 Firstly, SeqUnwinder is able to unravel sequence features associated with the dynamic bi

130 and root tissues of Nothapodytes nimmoniana unravels several putative pathway genes, transcription f

131 Our results unravel specific features of antiangiogenic resistance,

132 This modular approach also enables us to unravel static and photo-activated contributions to the

133 Our results unravel strong therapeutic opportunities by targeting tu

134 We unravel structure and mechanism of a previously unrecogn

135 Analyses of the variants unraveled that an N-terminal domain comprising a unique

136 In-depth molecular analysis unraveled that inhibition of peroxisome proliferator-act

137 e, the objective of the present study was to unravel the best brewing conditions for optimal extracti

138 ed 44 of the modifications to systematically unravel the biosynthesis of one of the most densely modi

139 In our attempt to unravel the collaboration between HCV and VLDL secretion

140 -dimensional coherent spectroscopy (2DCS) to unravel the complex optical response of monolayer MoSe2

141 ghlights the utility of genetic epistasis to unravel the complexities of JAZ-TF interactions and demo

142 ed by microbial interactions, as we begin to unravel the complexity of microbial interactions associa

143 on into the urine, allowing investigators to unravel the complexity of particulate-related health eff

144 of adult stem cells in tissue remodeling and unravel the complexity of stem cell fate determination.

145 Here, to unravel the components of the exocyst degradation pathwa

146 rocessing mechanisms, such tests should help unravel the conflicts between theory and data.

147 NMDA receptor subtypes, LiGluNs should help unravel the contribution of specific NMDA receptors to s

148 of human subjects, it has been difficult to unravel the effects of prenatal cocaine exposure on the

149 To unravel the emerging complexities of tRNA biology and mo

150 ps in the context of their life cycle can we unravel the evolutionary trajectory of hierarchical tran

151 Our results unravel the existence of a novel H2S-NO interaction and

152 Here we unravel the existence of a tumor-intrinsic-and microenvi

153 Here, for the first time we unravel the expression pattern and functional significan

154 te development, recent studies have begun to unravel the extensive cross-regulation of multiple signa

155 zolyl)borate copper thiolates [Cu(II)]-SR to unravel the factors involved in NO reactivity.

156 Therefore, we sought to unravel the functional mechanisms in different intasomes

157 To unravel the functional role of the C-terminal extension,

158 eural stem cells provide a system to further unravel the functions of DCX in normal development and d

159 In order to unravel the genes and the pathways associated with abnor

160 e heritable, recent advances have started to unravel the genetic architecture of the disease.

161 of our research in the past few years is to unravel the genetic causes of this form of diabetes.

162 ith dynamic Bayesian estimation, our results unravel the importance of proprioception for feedback co

163 The findings unravel the interaction network of possible RCAR-PP2C pa

164 ommunities is emerging as a promising way to unravel the interactions and biochemical repertoire of t

165 ty requires single-cell analyses designed to unravel the interplay of aging dynamics and cell-to-cell

166 ouse genetics and biochemical experiments to unravel the ligand-specific association of membrane prot

167 a range of mass spectrometric techniques to unravel the location and extent of PTMs in the chloropla

168 ly scalable nor sufficiently quantitative to unravel the magnitude and mode of action of many tumor-s

169 Here, we unravel the mechanical properties of SasG on the surface

170 In conclusion, our findings unravel the mechanism of AA action in regressing hypertr

171 To unravel the mechanism of action of ketamine, we treated

172 e this transposon as an experimental tool to unravel the mechanism of Helitron transposition.

173 This study aims to quantify the extent and unravel the mechanisms of saline-induced hyperemia.

174 Here, we unravel the mechanisms of the interactions among PlexinD

175 fone (PSF) ultrafiltration (UF) membranes to unravel the mechanisms underlying early stage membrane b

176 We unravel the mechanistic basis for fucosylation by AtFUT1

177 re-based functional analyses are required to unravel the mechanistic link between these processes.

178 The capability to unravel the mesoscale evolution of microstructure is dem

179 There is a pressing need to experimentally unravel the missing link between HIV and atherosclerosis

180 statistical recombination processes, and we unravel the mixture statistics to obtain a picture of th

181 ents will be valuable tools in the future to unravel the mode of action of these biomolecules at the

182 a multilayered chemical biology strategy to unravel the mode of action of this putative interkingdom

183 Our goal was to unravel the mode of Idd22-based protection using in vivo

184 preclinical work and genetics have begun to unravel the molecular architecture linking dopamine, psy

185 letal muscle formation will not only help to unravel the molecular basis of skeletal muscle diseases,

186 Thus, we have begun to unravel the molecular consequences of the 759G>T (p.L254

187 e this species in future studies intended to unravel the molecular control of heteromorphism and plas

188 organophosphate-induced hyperglycemia and to unravel the molecular mechanism behind this process.

189 n by a number of mechanisms, so we sought to unravel the molecular mechanism of the putative caspase-

190 To unravel the molecular mechanism underlying these disorde

191 gaining new insights into cAMP signaling and unravel the molecular mechanisms underlying ciliary func

192 prehensive (1)H NMR spectroscopy experiments unravel the network topology, confirming that, in isolat

193 These data unravel the novel function of FANCJ helicase in regulati

194 This helps unravel the oft-debated question of whether silk is push

195 Our data unravel the organization of tmTNF-mimetic scTNF ligands

196 rom the basal telencephalon, and may help to unravel the pathogenesis of several developmental brain

197 teriogenesis, meriting additional studies to unravel the pathways leading to improved collateral circ

198 These findings unravel the previously unidentified role that transcript

199 estivum L.) is a cornerstone in the quest to unravel the processes of domestication and the following

200 The aim of this study was to further unravel the protective effector mechanisms triggered by

201 To unravel the regulatory programs behind these changes, we

202 To unravel the respective role of chronic hypoxia and pulmo

203 New technologies that help to unravel the role of ambient aerosols in earth climate an

204 enesis are dysregulated in cancer, we aim to unravel the role of FSTL1-BMP4-Smad pathway in lung canc

205 This case prompted us to unravel the role of M. pneumoniae in GBS in a case-contr

206 Our findings unravel the role of Mn-catalase in acclimatization to sa

207 sis of CVB3-induced myocarditis, we aimed to unravel the role of NOD2 in CVB3-induced myocarditis.

208 han Hodgkin, used elegant genetic studies to unravel the sex determination pathway in Caenorhabditis

209 onventional secretion and provide a means to unravel the significance of the cytoplasmic versus the s

210 The kinetic data unravel the so far unknown substrate specificity and mec

211 n small grain cereals will enable to further unravel the transcriptional networks controlling this im

212 VTE and warrant future functional studies to unravel the underlying molecular mechanisms leading to V

213 and functional assays are needed to further unravel the unexplained heritability and biology of this

214 olved photoemission spectroscopy (ARPES), we unravel the unique surface Fermi arcs, in good agreement

215 This study sought to unravel the use of the mitochondrial marker cytochrome c

216 ormed three-way high-throughput screens that unraveled the complexity underlying host-microbe-drug in

217 Utilizing this set of simulations, we have unraveled the cooperative mechanism for polymer growth,

218 The in vitro digestion unraveled the enhanced liberation and bioaccessibility o

219 We have unraveled the molecular basis for filament assembly and

220 nance and molecular dynamics simulations, we unraveled the molecular determinants underlying cargo ca

221 Collectively, our findings unraveled the scope of the peroxide stress regulon and e

222 Novel molecular techniques have unraveled the tremendous diversity of intestinal symbion

223 ults contribute substantially to the task of unraveling the biological mechanisms giving rise to the

224 Unraveling the complexity of aging is crucial for unders

225 a represent an important step toward further unraveling the detailed molecular mechanism of ObgE, whi

226 Unraveling the doping-related charge carrier scattering

227 with no exception so far, may be the key to unraveling the foundations of observed behavior.

228 ed neurons deep in the brain is critical for unraveling the function of neuronal circuits but is chal

229 genomics offers an excellent opportunity for unraveling the genetic history of crop domestication.

230 Unraveling the genetics of the paralytic strabismus synd

231 is of increasing importance, especially for unraveling the influence of microplastics on our health

232 esented here establish a direct approach for unraveling the mechanisms and main parameters underlying

233 Unraveling the mechanisms causing increased viral transm

234 Unraveling the mechanisms of microbial adaptive evolutio

235 adhesion, and serves as a starting point for unraveling the molecular architecture of a robust and un

236 ell divisions and that could pave the way to unraveling the molecular basis behind ACR4-mediated sign

237 Unraveling the molecular mechanism of Kgp zymogenicity i

238 Unraveling the molecular mechanism of these rare genetic

239 ill stimulate fruitful research that aims at unraveling the molecular pathways through which our life

240 ete knowledge of the underlying interactions unraveling the nature of this continuum remains challeng

241 and where they work is a potential route to unraveling the neural mechanisms that underlie awareness

242 Unraveling the non-equilibrium behavior of such topologi

243 e to genetic variation are key questions for unraveling the origin and evolvability of this feature o

244 molecular architecture of PrP(Sc) is key to unraveling the pathology of prion diseases.

245 st decade has brought tremendous progress in unraveling the pathophysiology of Alzheimer's disease (A

246 minants of postnatal eNO levels might aid in unraveling the role of eNO in epithelial function or air

247 Substantial progress has been made in unraveling the sensory transduction mechanisms, commonly

248 However, unraveling the solution-state supramolecular structures

249 Our work provides a basis for unraveling the substrate oxidation mechanism in GMC enzy

250 Accordingly, unraveling the sugar composition of bacterial cell surfa

251 Unraveling the transcriptional regulatory network for in

252 pecific distribution arises is important for unraveling the translation mechanism.

253 Here, we aim at unraveling the true potential of plasmonics by exploitin

254 anisms for all communications remain opaque, unraveling the wiring of organelle networks is critical

255 mour spheroids embedded in a collagen matrix unravelled the efficacy of cell-cell contact loosening a

256 In this perspective, unravelling the atomistic structure that originates the

257 sed Case-Cohort sample (iPSYCH2012) aimed at unravelling the genetic and environmental architecture o

258 itative trait loci or eQTLs) is important in unravelling the genetic basis of complex traits.

259 Unravelling the mechanisms driving niche shifts can shed

260 Unravelling the molecular basis of TLR1 and TLR6-driven

261 hese seven novel genes has been important in unravelling the molecular mechanisms underlying ALS.

262 Binding in this conformation involves unravelling the outer turn of nucleosomal DNA and requir

263 erfly, identifying sensitive life stages and unravelling the role life-history traits play in species

264 the retina and significantly contributes to unravelling the role of specific miRNAs in cone photorec

265 Family studies are ideally suited to unravelling the role of these factors.

266 t on science, and are a critical element for unravelling the structural dynamics of matter.

267 f genetic and epigenetic research focused on unravelling the underpinnings of adiposity.

268 tion of an FSA biosynthetic pathway, thereby unravelling the unique formation of a hybrid metabolite

269 ity, particularly without preactivation that unravels the CHP homotrimers.

270 This study unravels the dynamic yet discrete self-organization of m

271 ur combined experimental-computational study unravels the folding-functional landscape of a natural t

272 The identification of Ms2 not only unravels the genetic basis of a historically important b

273 This work unravels the importance of addressing quantitatively the

274 This study unravels the in vivo performance of stem cells during ti

275 Our study unravels the molecular mechanism and cellular machinery

276 Ultimately, this in-depth study unravels the principles of tandem catalysis related to h

277 contacts with other organelles, and further unravel their communication.

278 any human cancers, but tools to more quickly unravel their functional contributions are needed.

279 e synthesized TA fragments have been used to unravel their role in immunology and it is described how

280 bundling of fascin or L-plastin, we further unraveled their cooperative mode of action.

281 Although neuroimaging studies have been unraveling their neural correlates, how integration take

282 atomies, fossils have been of limited use in unravelling their evolutionary origin, as the earliest r

283 theless, translational studies have begun to unravel these distinct pathologies, identifying novel tr

284 ndividually identifiable neurons can help to unravel these issues.

285 Our aim was to unravel these mechanisms using FL-N/35 transgenic mice e

286 However, in vitro studies that could unravel these potential roles have been hampered by the

287 ative mass spectrometry (MS) offers a way to unravel this inherent heterogeneity of protein assemblie

288 To unravel this puzzle, we employed a poly(A) tag sequencin

289 To unravel this relationship, we analyzed eight multiscale

290 Unraveling this complex PTM code is one of the great cha

291 cent years, adding a new sense of urgency to unraveling this mystery.

292 quares Henderson-Hasselbalch global fitting, unravels three distinct pH-dependent secondary structure

293 rules governing system-level behavior can be unraveled through the application of wholly synthetic ne

294 isms underlying resistance are not yet fully unraveled; thus our research focused on the identificati

295 e have utilized single-molecule detection to unravel Top2 DNA gate dynamics and reveal previously unk

296 Here, we unravel two manifestations of ergodicity breaking in the

297 sequencing (WGS) is a promising strategy to unravel variants or genes responsible for human diseases

298 studies) and computational progress towards unravelling various excited state decay mechanisms that

299 now clear, and its molecular basis is being unraveled, while recent studies have identified possible

300 of caspase-1 and caspase-11 are difficult to unravel without additional genetic tools.