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1  mitosis, TopBP1 marks sites of and promotes unscheduled DNA synthesis.
2 atin recruitment of SLX4 and by facilitating unscheduled DNA synthesis.
3 as determined by phosphorylation of H2AX and unscheduled DNA synthesis.
4 (2-4 Gy) alone provokes a marked increase in unscheduled DNA synthesis, a measure of DNA repair, but
5 vity compared with wild-type, as assessed by unscheduled DNA synthesis after UV irradiation (10J/m2)
6 53-deficient hepatocytes also showed reduced unscheduled DNA synthesis after UV, but there was no imp
7 ion in G1, as measured by RAD51 recruitment, unscheduled DNA synthesis and a CRISPR-Cas9-based gene-t
8 ed a reduced capacity for NER as measured by unscheduled DNA synthesis and host cell reactivation ass
9  in two independent assays that measure NER (unscheduled DNA synthesis and host cell reactivation), t
10 lobutane pyrimidine dimers from bulk DNA, or unscheduled DNA synthesis and, therefore, do not involve
11 orporating 5'-bromodeoxyuridine, a marker of unscheduled DNA synthesis and/or cell proliferation.
12 es promote cell cycle progression, stimulate unscheduled DNA synthesis, and present the cell with an
13 e I breast tumors tested with the functional unscheduled DNA synthesis assay exhibited a significant
14  1 (CDK1) activity, DNA damage responses, or unscheduled DNA synthesis but to loss of an ATR function
15 ermined by measurements of repair synthesis (unscheduled DNA synthesis), by immunoassays to detect re
16 vation of u.v.-damaged reporter plasmids and unscheduled DNA synthesis experiments in transiently-tra
17 tion and defective DNA repair (16% of normal unscheduled DNA synthesis in intact cells and undetectab
18  to be deficient in their ability to conduct unscheduled DNA synthesis in response to UV-induced DNA
19 a included increased cellular proliferation, unscheduled DNA synthesis, increased E2F-responsive gene
20 n was maximum with the drug combination, and unscheduled DNA synthesis induced by bendamustine was bl
21 a pigmentosum variant cells exhibited normal unscheduled DNA synthesis, normal recovery of RNA synthe
22 st that p21cip1 induction effectively blocks unscheduled DNA synthesis reactivated by E7.
23 eterozygotic parents showed normal levels of unscheduled DNA synthesis, recovery of RNA synthesis, an
24 or DNA repair after ultraviolet irradiation: unscheduled DNA synthesis, recovery of RNA synthesis, an
25            Two commonly used assays are UDS (unscheduled DNA synthesis, requiring a precise measureme
26 splatin or doxorubicin led to an increase in unscheduled DNA synthesis that was reduced by combined t
27 ER-2 and radiation demonstrate a decrease of unscheduled DNA synthesis to 25-44% of controls.
28 to UV irradiation and show reduced levels of unscheduled DNA synthesis (UDS).
29        The level of ultraviolet (UV)-induced unscheduled DNA synthesis was less than 5% of normal, ch
30 eotide excision repair (NER), as measured by unscheduled DNA synthesis, was accelerated by PAF and 5-
31        An alternative measure of DNA repair, unscheduled DNA synthesis, was also assessed.

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