ライフサイエンスコーパス: unselected

1 ood was studied prospectively in a cohort of unselected 8th-grade schoolchildren established in 1995

2 ly reflecting choice-specific suppression of unselected actions.

3 described small airway disease, with >40% of unselected adolescent clinic attendees meeting criteria

4 The public survey included unselected adults, whereas the patient survey captured i

5 he sibling recurrence risk ratio, sequencing unselected affected individuals may be preferable.

6 in family-based designs or designs based on unselected affected individuals.

7 A total of 2,098 unselected all-comer patients (50% with acute coronary s

8 The unselected AMC and ckit(+)AMC-treated mice demonstrated

9 arms: (1) normal saline control (n=14), (2) unselected AMCs (n=10), (3) ckit(+)AMCs (n=13), and (4)

10 ned in a murine myocardial injury model: (1) unselected AMCs, (2) ckit(+)AMCs, and (3) AMC-derived in

11 onnaire at baseline and 1 year later in 2693 unselected AMI patients from 24 hospitals enrolled in th

12 th rigorously defined s-AML or t-AML and 105 unselected AML patients.

13 an population and include all patients in an unselected and consecutive manner.

14 enters without on-site cardiac surgery in an unselected and nationally representative population of t

15 l rate Temprid, and then reared progeny from unselected and selected strains.

16 ing which the mortality risk manifests in an unselected and untreated population, which can guide scr

17 % for PPS23F, significantly higher than both unselected B cells and PPS-specific B cells.

18 Phenotypic analysis of unselected B cells, pre- and postimmunization, demonstra

19 ulting marker-selected stock outperformed an unselected benchmark stock in terms of hygienic behavior

20 onal methods to investigate rejection in 703 unselected biopsies taken 3 days to 35 years post-transp

21 ated our results in an independent set of 74 unselected biopsy specimens.

22 Verification was sought in an independent unselected birth cohort (BAMSE) constituting 3051 childr

23 ears) from the Infant Immune Study (IIS), an unselected birth cohort closely monitored for asthma for

24 function were assessed longitudinally in two unselected birth cohorts and cross-sectionally among inf

25 FAIR (Food Allergy and Intolerance Research) unselected birth cohorts were established in 1989 and 20

26 allergic sensitization from two independent unselected birth cohorts, we identified latent classes w

27 Not much data are available from large, unselected, birth cohort studies on the natural course a

28 sponses compared with recipients of HSC plus unselected bulk T cells.

29 Known pathogenic CNVs in unselected, but assumed to be healthy, adult populations

30 ed myocardium was then compared with that of unselected c-kit(+) hCSCs.

31 rol, cohort, and cross-sectional studies and unselected case series were eligible for inclusion.

32 6p or 11q, respectively; however, screening unselected cases identified missense mutations in EED (1

33 nts were simultaneously attracted toward the unselected category response, indexing the degree to whi

34 cal and laboratory data from 749 consecutive unselected CD children diagnosed by national referral ce

35 Our ability to direct localization of unselected CD8 T cells into B-cell follicles using CXCR5

36 er B-cell follicles, we genetically modified unselected CD8 T cells to express CXC chemokine receptor

37 Here, we demonstrate that engineering unselected CD8 T cells to express CXCR5, a chemokine rec

38 array occur at a rate of >10(-3)/division in unselected cells.

39 es not adversely affect exercise capacity in unselected CHF patients.

40 to mothers with asthma (COPSAC2000 ) and 700 unselected children (COPSAC2010 ) were analyzed followin

41 Design: Unselected children with newly diagnosed and previously

42 s was significantly higher in FR-CLL than in unselected CLLs at diagnosis (10.3% vs 1.1%, P = .004),

43 fter a median follow-up of 7.2 years, in the unselected cohort (n = 6,211) increasing exercise exposu

44 EXCOR to characterize device outcomes in an unselected cohort and to identify risk factors for morta

45 addition of vismodegib to gemcitabine in an unselected cohort did not improve overall response rate,

46 Analysis of BCORL1 in an unselected cohort of 173 AML patients identified a total

47 In a prospective study, an unselected cohort of 66,822 participants with and withou

48 e clinical course of atopic dermatitis in an unselected cohort of adolescents followed into adulthood

49 ults to predict overall mortality in a large unselected cohort of diabetic and nondiabetic patients.

50 In a large adult-predominant unselected cohort of mainly relapsing CNS inflammatory d

51 th major adverse cardiovascular events in an unselected cohort of patients undergoing elective, nonca

52 to evaluate late toxicity and survival in an unselected cohort of patients who experienced relapse af

53 udies have shortcomings, we present a large, unselected cohort of patients who have undergone close m

54 herefore, a prevention strategy targeting an unselected cohort of seropositive patients with acute re

55 barachnoid Aneurysm Trial in a retrospective unselected cohort of subarachnoid hemorrhage patients.

56 ures of patients from a large adult-dominant unselected cohort with mainly relapsing central nervous

57 In a nationwide unselected cohort, the performance of the RCRI was simil

58 hort, and 62% as a cumulative estimate in an unselected cohort.

59 cancer-related death for: (i) all patients ("unselected" cohort), and on the basis of (ii) classic cl

60 al characteristics and long-term outcomes of unselected, community-based patients with left ventricul

61 of management of atrial fibrillation (AF) in unselected, community-based patients.

62 An unselected consecutive group of 389 adults with a mean a

63 We present a 4-year study with 262 unselected consecutive high-risk episodes, prospectively

64 In this cohort of unselected consecutive patients with acute pancreatitis

65 In RCT No. 2, a total of 154 unselected consecutive patients with cirrhosis and acute

66 In RCT No. 1, a total of 211 unselected consecutive patients with cirrhosis and acute

67 study was a multicenter prospective study of unselected consecutive patients with low rectal cancer r

68 g T1 and T2 mapping, compared with EMB in an unselected, consecutive patient cohort with suspected my

69 Unselected, consecutive, incident patients with pancreat

70 In an unselected contemporary population of HF with reduced ej

71 iated with reduced mortality also in a broad unselected contemporary population with HF and reduced e

72 h DSM-IV OCD, a subset of their parents, and unselected controls, were genotyped with several differe

73 lining fluid in 309 neonates from the novel unselected Copenhagen Prospective Study on Asthma in Chi

74 n born to mothers with atopic disease in the unselected COPSAC2010 cohort (adjusted HR = 0.39 [0.19-0

75 Replication was performed in the unselected COPSAC2010 cohort with follow-up until 5 year

76 ver the hazard ratio patterns present in the unselected data sets: The corrections overshot the targe

77 Therefore, either unselected DLIs or EBV-specific CTLs can eradicate both

78 with human HCMV-convalescent-phase sera from unselected donors confirmed the conserved antibody respo

79 illation risk haplotype) in a cohort of 1440 unselected Dutch SCA victims included in the Amsterdam R

80 k factors and incident severe AS in a large, unselected elderly population.

81 We analysed unselected emergency admissions to four Oxford Universit

82 pital trusts were those in England receiving unselected emergency admissions.

83 n-18, and cystatin C) were measured in 1,635 unselected emergency department patients at the time of

84 In unselected estrogen receptor-positive/HER2-negative pati

85 both selected LOH events on chromosome V and unselected events throughout the genome in untreated cel

86 hmia secondary variants can be identified in unselected exomes.

87 s a reference group for APC mutations in the unselected FAP population, we used the UMD-APC database

88 ling Test in a large sample of patients with unselected focal frontal (n = 60) and posterior (n = 30)

89 Cells analyzed were either unselected for a specific subpopulation or phenotypicall

90 population-based endometrial cancer cohort, unselected for age or family history, were analyzed to d

91 mother-child pairs from a US prebirth cohort unselected for any disease were studied.

92 mother-child pairs from a US prebirth cohort unselected for any disease.

93 peripheral-blood cells from 12,380 persons, unselected for cancer or hematologic phenotypes.

94 tic variants with EOC risk from 15,437 cases unselected for family history and 30,845 controls and fr

95 ts with triple-negative breast cancer (TNBC) unselected for family history of breast or ovarian cance

96 Patients with TNBC (N = 1,824) unselected for family history of breast or ovarian cance

97 cumented metastatic prostate cancer who were unselected for family history of cancer or age at diagno

98 sent at high frequency in patients with TNBC unselected for family history of cancer.

99 g men with localized prostate cancer who are unselected for family predisposition is insufficient to

100 heral-blood cells of 17,182 persons who were unselected for hematologic phenotypes.

101 yelofibrosis and 252 637 population controls unselected for hematologic phenotypes.

102 tibility gene mutations in patients with CRC unselected for high-risk features (eg, early age at diag

103 Patients unselected for PD-L1 expression received avelumab (10 mg

104 essing after platinum-based chemotherapy and unselected for PD-L1 expression received avelumab 10 mg/

105 Controls are often "unselected" for the disease of interest and are not matc

106 Here we measure the unselected formation rate and the growth contribution of

107 r azithromycin confers a similar risk in the unselected general population is unknown.

108 s, but effectiveness has not been studied in unselected general populations unrestricted by region, f

109 Notably, residual tumors from an unselected group of BC patients treated with neoadjuvant

110 urvival advantage over erlotinib alone in an unselected group of patients with advanced NSCLC.

111 ality, stroke rate and other morbidity in an unselected group of patients with coronary artery diseas

112 We analyzed a cohort of 110 unselected HCV patients who started triple therapy from

113 NGS methods using (i) unselected HCV RNA (metagenomics), (ii) preenrichment of

114 mpared with docetaxel alone when given to an unselected HER2/neu-negative cohort as first-line treatm

115 seeds within the mesocosm community carrying unselected, hitchhiking transgenes.

116 Consecutive unselected HIV-infected adults in South Africa were syst

117 thousand six hundred ninety-five consecutive unselected ICU admissions during a six-month period in 2

118 We conclude that 1/30 unselected individuals harbor a pLOF mutation associated

119 e extent of familial clustering of MVP among unselected individuals in the community using current, m

120 itral valve prolapse (MVP) progression among unselected individuals in the community, including those

121 Genetic screening programs in unselected individuals with increased levels of low-dens

122 ut very large samples (for example, >250,000 unselected individuals) will be required to localize mos

123 This cohort study included unselected infants born at NTT Medical Center Tokyo betw

124 f 872 nasal swabs collected biweekly from 47 unselected infants.

125 ncluding inceptive and validation cohorts of unselected intensive care unit patients, demonstrates th

126 Median PFS in the unselected intent-to-treat population was 3.75 months wi

127 Among unselected intermediate- and high-risk patients, TAVR an

128 er compared with that in previously reported unselected IRD cohorts.

129 nding of the relevance of these cells in 100 unselected kidney transplant recipients followed prospec

130 ing genome-wide germline SNP genotypes in an unselected large cohort of children with ALL, we observe

131 cleotide composition existed in the initial, unselected libraries purchased from two different manufa

132 from each selected pool and compared to the unselected library.

133 ve line, while simultaneously maintaining an unselected line to serve as the Control.

134 unity against a viral pathogen compared with unselected mature T cells.

135 nonmetastatic cell lines but contrary to the unselected metastatic cell population.

136 a prospective birth cohort of 366 infants of unselected mothers, respiratory health was assessed week

137 ic endophenotypes for schizophrenia in large unselected multigenerational pedigrees.

138 To generate a large number of unselected mutations, we immunized B1-8 H chain transgen

139 known respiratory virus-positive (n= 42) and unselected (n= 67) pediatric nasopharyngeal swabs using

140 ion DES, and newer generation DES in a large unselected national data set from the BCIS (British Card

141 rcutaneous coronary intervention (PCI) in an unselected nationwide cohort over the past 2 decades.

142 are associated with improved outcomes in an unselected nationwide population of patients with HF wit

143 In an unselected nationwide population of patients with HF wit

144 Response rates of unselected non-small cell lung cancer (NSCLC) patients t

145 No significant association was detected for unselected OC cases (OR, 1.74; 95% CI, 0.57-5.08; P = .2

146 e the validation classified the 69.6% of the unselected original cases.

147 nvestigate coronary angiographic findings in unselected out-of-hospital cardiac arrest patients refer

148 ion NORd-Pas-de-Calais) study enrolled 4,184 unselected outpatients with stable CAD (i.e., MI or coro

149 of BRCA(1/2) mutations in germline DNA from unselected ovarian cancer patients is 11% to 15.3%.

150 ion of HBEC-selected parasites compared with unselected parasites by antibodies from young African ch

151 nscriptome of isogenic pairs of selected and unselected parasites was analyzed using a variant surfac

152 The frequency of GBA mutations in unselected Parkinson's disease populations has not been

153 The estimated FH prevalence was 1:256 in unselected participants and 1:118 in participants ascert

154 from those in research settings, even in an unselected patient population in which oral failure was

155 omitinib was not superior to erlotinib in an unselected patient population with advanced non-small-ce

156 enefit to current EGFR-targeted agents in an unselected patient population, and highlight the need fo

157 wing to the impossibility of including large unselected patient populations in randomized clinical tr

158 frequency of related clinical phenotypes in unselected patient populations is not well established.

159 from the current large, randomized trials in unselected patient populations to smaller trials in grou

160 sive disease and cough reflex sensitivity in unselected patients (ie, including non-GOR causes) with

161 Unselected patients (N=1954) presenting to the emergency

162 atment response, sputum samples (n=124) from unselected patients (n=35) with sputum microscopy-positi

163 Over 14 months, all unselected patients admitted to an adult intensive care

164 el data describing the procedure's safety in unselected patients are lacking.

165 ned acute myeloid leukaemia blast cells from unselected patients attending our UK hospital between Fe

166 cond-line treatment in oesophageal cancer in unselected patients does not improve overall survival, b

167 rior to the biolimus-eluting Nobori stent in unselected patients for target lesion failure at 1 year.

168 l Hyperplasia Study (PRODIGY) trial assessed unselected patients from tertiary care hospitals with st

169 ted mortality, stroke rate, and morbidity in unselected patients in comparison to conventional CABG.

170 g of 246 Staphylococcus aureus isolates from unselected patients in Thailand showed that 10 (4.1%) we

171 In METREX, unselected patients in the modified intention-to-treat p

172 axel in unselected patients, or erlotinib in unselected patients may be considered.

173 We prospectively enrolled unselected patients presenting to the emergency departme

174 ctive multicenter diagnostic study enrolling unselected patients presenting with suspected non-ST-seg

175 han-expected rate of EGFR mutations in these unselected patients raises the possibility that EGFR-mut

176 ural administration of rectal indometacin in unselected patients reduced the overall occurrence of po

177 rta (Ao) ratio is associated with outcome in unselected patients referred for cardiac magnetic resona

178 en TpTe and markers of DD in 84 consecutive, unselected patients referred for exercise echocardiograp

179 Eight hundred ninety-two unselected patients treated intensively in the United Ki

180 aluation of the health status outcomes among unselected patients treated with TAVR is of critical imp

181 Among unselected patients undergoing PCI in the drug-eluting s

182 Among unselected patients undergoing PCI, GIB has a profound e

183 histology, or Asian ethnicity); thereafter, unselected patients were included to a total of N = 60.

184 December, 2006 until June, 2008, molecularly unselected patients were recruited to a three-arm design

185 agents have been negative, but these were in unselected patients where it was unknown whether the tar

186 presentation and serially thereafter in 887 unselected patients with acute chest pain.

187 red with femoral access improves outcomes in unselected patients with acute coronary syndromes underg

188 focal brain lesions (n = 581), derived from unselected patients with acute ischaemic injury (mean ag

189 ence of early death in a large population of unselected patients with acute promyelocytic leukemia (A

190 ygen has recently shown survival benefits in unselected patients with acute respiratory failure.

191 t be recommended for routine clinical use in unselected patients with advanced chronic obstructive pu

192 litaxel did not significantly improve PFS in unselected patients with advanced melanoma.

193 Erlotinib prolonged survival of unselected patients with advanced non-small-cell lung ca

194 e efficacy of vandetanib versus erlotinib in unselected patients with advanced non-small-cell lung ca

195 In unselected patients with advanced NSCLC, first-line erlo

196 Data for 173,233 unselected patients with an AMI, including 33,503 patien

197 stopathologic assessment was conducted in 83 unselected patients with biopsy-proven NAFLD from a sing

198 Unselected patients with chest pain presenting at emerge

199 daptive pacing (versus fixed-rate pacing) in unselected patients with CHF does not improve peak exerc

200 In unselected patients with cirrhosis, who underwent succes

201 efinitive results of these long-term RCTs in unselected patients with cirrhosis.

202 We found that 30% of unselected patients with community managed asthma were c

203 lence and spectrum of these conditions among unselected patients with early-onset colorectal cancer (

204 eceptor (EGFR) tyrosine kinase inhibitors in unselected patients with head and neck squamous cell car

205 ur registry, we have analyzed a total of 500 unselected patients with HLH.

206 linical phenotype of PA in a large cohort of unselected patients with hypertension, consecutively ref

207 r clinical and duplex ultrasound assessment, unselected patients with intermittent claudication reque

208 alth-related quality of life after 1 year in unselected patients with intermittent claudication.

209 RET that produced a 10% overall response in unselected patients with lung cancers.

210 ic medulloblastomas, we screened a series of unselected patients with medulloblastoma for germline SU

211 of SIRT in combination with chemotherapy in unselected patients with metastatic colorectal cancer ca

212 b, single-agent foretinib lacked efficacy in unselected patients with metastatic gastric cancer.

213 ab compared with bevacizumab plus placebo in unselected patients with recurrent glioblastoma in this

214 minimal evidence of single-agent activity in unselected patients with recurrent malignant glioma.

215 l-tolerated, but does not improve outcome in unselected patients with recurrent NSCLC.

216 ove outcomes in poor prognosis but otherwise unselected patients with SCCHN.

217 creased mortality when it is administered to unselected patients with septic shock.

218 In this study of unselected patients with ST-segment-elevation myocardial

219 Use of SBRT with erlotinib for unselected patients with stage IV NSCLC as a second- or

220 rge study of prospective mutation testing in unselected patients with TC, molecular signature was ass

221 nnot be recommended as adjuvant treatment in unselected patients with triple-negative breast cancer.

222 nd PROS1 testing should not be considered in unselected patients with venous thrombosis.

223 Among 2813 unselected patients, 447 (16%) had renal dysfunction (de

224 Of the 2,098 unselected patients, 73.1% were still alive after 10 yea

225 al, contemporary clinical practice cohort of unselected patients, improvement in health status after

226 nts with nonsquamous histology, docetaxel in unselected patients, or erlotinib in unselected patients

227 acy of NACT by extent of residual disease in unselected patients.

228 d the drugs provided insufficient benefit in unselected patients.

229 sed in a long-term population-based study of unselected patients.

230 paclitaxel did not result in improved PFS in unselected patients.

231 in other malignancies have failed to benefit unselected PDA populations, although patients do occasio

232 prognostic significance of SNP rs11554137 in unselected pediatric and adult AML patients.

233 Compared with unselected peripheral blood mononuclear cells, CMV-CTLs

234 Unselected peripheral blood stem cells were harvested wi

235 er yielded no benefit in the treatment of an unselected population and should not be used.

236 population equivalent to IQ > 147) and 3,253 unselected population controls.

237 , post-mortem, whole-body MRI at 1.5 T in an unselected population of fetuses (</=24 weeks' or >24 we

238 ated with improved mortality/morbidity in an unselected population of HFmrEF and HFpEF patients.

239 response associations with incident AS in an unselected population of older individuals, and together

240 vascularization on long-term prognosis in an unselected population of patients with and without T2DM.

241 ested in therapeutic trials starting from an unselected population of patients with metastatic melano

242 In an unselected population of patients with nonsquamous NSCLC

243 (Pd/Pa vs iFR in an Unselected Population Referred for Invasive Angiography

244 opulation of the VERIFY2 (Pd/Pa vs iFR in an Unselected Population Referred for Invasive Angiography)

245 ival and cannot be recommended for use in an unselected population with advanced oesophagogastric ade

246 In an unselected population, the putatively pathogenic genetic

247 lation distribution of intelligence and 8172 unselected population-based controls.

248 lation distribution of intelligence and 3253 unselected population-based controls.

249 track disease evolution from diagnosis in an unselected population-representative incident cohort.

250 e IPFSG classification was confirmed in this unselected population.

251 ing patients after TAVR in the context of an unselected population.

252 ne/inflammatory serologic markers in a large unselected population.

253 Particularly in unselected, population-based cases, considering putative

254 luated several progression algorithms in our unselected, population-based cohort for risk prediction

255 alyzing prognostic factors and outcome in an unselected, population-based cohort.

256 Decoding from unselected populations enables a read-out of motivationa

257 tiangiogenic agents may not be beneficial in unselected populations of patients with GBM.

258 Multicenter data from large unselected populations on patients' radiation doses duri

259 of ABI testing in primary care populations, unselected populations, and asymptomatic populations; th

260 ctiveness in preventing vasovagal syncope in unselected populations, but they might be effective in o

261 abdominal symptoms in primary care or other unselected populations, IgA antitissue transglutaminase

262 Its performance in unselected populations, including different age groups,

263 dentally detected PE ranges from 1% to 4% in unselected populations, with higher rates among hospital

264 ng for major CVD outcomes in primary care or unselected populations; and the effect of treatment on g

265 However, it is unclear in unselected "real-world" patients if sources drive persis

266 xplain less variability for yield G x E than unselected regions, indicating that improvement by breed

267 te IGH@ V-D-J sequences can be computed from unselected RNA-seq reads with results equal or superior

268 ce of intelligence in the normal range in an unselected sample of 3414 individuals, which is comparab

269 ciated with measured cognitive ability in an unselected sample of 4854 participants of European ances

270 examined the rate of mental disorders in an unselected sample of homicide defendants in a U.S. juris

271 n the fly (without any training) in a large, unselected sample of Italian and French dyslexic childre

272 conclusions about lateralization based on an unselected sample of the population and laterality asses

273 ifferences in intelligence in an independent unselected sample.

274 In unselected samples, untargeted metagenomics had excellen

275 be informed by penetrance estimates of HH in unselected samples.

276 In unselected SCA victims from the community, common geneti

277 Of 7,287 unselected schoolchildren screened, 115 were ICA(+) and

278 A prospective unselected series of 20 patients with symptomatic or asy

279 an have a much higher yield than in previous unselected series.

280 capacity (Low Capacity Runners, LCR), and 3) unselected Sprague-Dawley (SD) rats with or without free

281 rformance as applied directly to consecutive unselected sputum samples has not been established.

282 ficantly less susceptible to Temprid SC than unselected strains.

283 Two years after enrollment, an unselected subgroup of 188 children were enrolled into l

284 Further including 20% of unselected symptomatic individuals in the public sector

285 neous CAR-T cell products were prepared from unselected T cells.

286 in plant communities through hitchhiking of unselected traits.

287 s and treatment burden data of 56 eyes of 54 unselected treatment naive patients diagnosed with exuda

288 al cells clustered differently compared with unselected tumor and normal cells.

289 and more effective as an antigen source than unselected tumor cells in inducing protective antitumor

290 We show that in a representative, unselected UK Parkinson's disease population, GBA mutati

291 The expression of the HP in unselected VH4-34 cells was assessed by deep sequencing.

292 likely to harbor anti-brain antibodies than unselected women of child-bearing age (10.5 vs 2.6%).

293 m Simon Simplex Collection and plasma of 653 unselected women of child-bearing age for anti-brain ant

294 We provide evidence that unselected women with these thrombophilias have an incre

295 muscle were studied among selected (FP) and unselected (WP) Atlantic salmon lines that were reared t

296 Twelve patients responded to therapy with unselected young TILs (according to Response Evaluation

297 neous tumors, eight of 15 patients receiving unselected young TILs responded but none of eight patien

298 anoma were prospectively assigned to receive unselected young TILs versus CD8(+)-enriched TILs.

299 Thirty-four patients received unselected young TILs with a median of 8.0% CD4(+) lymph

300 s to prepare, future studies should focus on unselected young TILs.