ライフサイエンスコーパス: unstable

1 ell binding (the Ail-Deltaloop 1 protein was unstable).

2 energy-density materials, but are inherently unstable.

3 ing nuclear integrants are often immediately unstable.

4 osomes and micronuclei, and were genetically unstable.

5 ecular orbital cause them to be reactive and unstable.

6 unts of carbon without being gravitationally unstable.

7 es more localized as the system becomes more unstable.

8 s of the O and SAT serotypes, is notoriously unstable.

9 zyme-dead MLL4 protein in ES cells is highly unstable.

10 mics with nearly one-half of the phase space unstable.

11 tron bound by 1.1 eV, while CB11 H12 (2-) is unstable.

12 wed that the PEHO syndrome mutant protein is unstable.

13 at suggest epsilon-plutonium is mechanically unstable.

14 ir benefits to human health; it is, however, unstable.

15 -substituted analogues are configurationally unstable.

16 egy conveniently avoids the isolation of the unstable 3,3-difluorocyclopropenylcarbinyl glycolates ar

17 d results in the formation of talin-rich but unstable adhesions.

18 dict fluid responsiveness in hemodynamically unstable adult patients who were defined as having refra

19 ting fluid responsiveness in hemodynamically unstable adults.

20 on mu-1,2-peroxodicobalt(III) intermediate 2 unstable against a preferential proton-transfer step at

21 However, circulating neutrophils form unstable aggregates and are unexpectedly primed to respo

22 An unstable, alkynyl-tagged curcumin analog yielded abundan

23 and strong fluorescence, in contrast to the unstable all-carbon bistetracene.

24 his flow process enables practical use of an unstable allenyllithium intermediate.

25 ecreased by pretreatment with curcumin or an unstable analog but not by a stable analog.

26 In contrast, diazotriazoles are rather unstable and are mainly handled in solution and/or low t

27 hogenic viruses, bacteria, and parasites are unstable and cannot be produced cheaply for clinical use

28 Complex 6 is thermally unstable and degrades via P-N bond cleavage to form a Nb

29 ding azulenyl halides, which are known to be unstable and difficult to prepare in pure form.

30 are formed de novo each cell cycle, but are unstable and do not persist to the next cell cycle, lead

31 agnetic field near the solar surface becomes unstable and erupts.

32 trinsic or intrinsic factors that promote an unstable and hyperosmolar tear film.

33 e, and several numerical models suggest that unstable and irreversible retreat of the grounding line-

34 scued P23H rhodopsin was still intrinsically unstable and led to increased structural instability of

35 ed from single transcriptomic study is often unstable and not generalizable due to cohort bias and li

36 ngle transcriptomic study, however, is often unstable and not generalizable due to cohort bias, biolo

37 However, expression was unstable and poor.

38 XBAT35.2 was found to be unstable and promotes its own degradation, suggesting se

39 wever, these small peptides are likely to be unstable and rapidly cleared from the circulation, and t

40 Many long noncoding RNAs (lncRNAs) are unstable and rapidly degraded in the nucleus by the nucl

41 , the genome-free capsids (ECs) of wt PV are unstable and readily change antigenicity to a form not s

42 Consequently, the damaged forks become unstable and resistant to repair.

43 f-assembling building block is intrinsically unstable and spontaneously reverts to its original precu

44 with population-based inferences suggest an unstable and stable bTB-endemic status in the North-West

45 ere, we test the link between a memory being unstable and the transfer of learning to a different typ

46 However, these compounds were unstable and their stabilization had to be achieved by m

47 hat happen to be constitutively or inducibly unstable, and in this capacity it plays a regulatory rol

48 l-type effects, its performance was somewhat unstable, and it carried a risk of missing true signals

49 ligand-binding domains (LBDs) are inherently unstable, and their crystallization requires extensive m

50 A cancer genome is typically unstable, and thus more mutations can accumulate in the

51 Emergently admitted patients with unstable angina (n = 33 901) who did or did not receive

52 for unplanned coronary revascularization and unstable angina (UA) are common.

53 sion [n = 7], myocardial infarction [n = 5], unstable angina [n = 3], pericarditis [n = 2], arrhythmi

54 Likewise, clinical scenarios with unstable angina and intermediate- or high-risk features

55 t elevation acute coronary syndromes include unstable angina and non-ST-segment elevation myocardial

56 Patients with unstable angina benefit from an invasive management path

57 The adjusted odds of MACE for the unstable angina group were similar to those for the non-

58 s all-cause death, myocardial infarction, or unstable angina hospitalization over a median follow-up

59 rtality, nonfatal myocardial infarction, and unstable angina hospitalization was similar and fair for

60 omposite of death, myocardial infarction, or unstable angina hospitalization.

61 d point was death, myocardial infarction, or unstable angina hospitalizations over a median follow-up

62 Unstable angina or non-ST-elevation myocardial infarctio

63 ch additionally included hospitalisation for unstable angina requiring unplanned revascularisation) a

64 rction, nonfatal stroke, hospitalization for unstable angina requiring urgent revascularization, or c

65 g angiography within 2 months of their index unstable angina versus 0.097 (CI, 0.090 to 0.105) for th

66 placebo, on acute coronary syndromes (MI and unstable angina) among IRIS participants.

67 on, non-fatal stroke, hospital admission for unstable angina, and hospital admission for heart failur

68 scular disease (CVD) (myocardial infarction, unstable angina, arterial revascularization, stroke, or

69 (fatal and nonfatal myocardial infarctions, unstable angina, deaths from coronary heart disease, fat

70 or non-fatal stroke, hospital admission for unstable angina, hospital admission for heart failure, d

71 or non-fatal stroke, hospital admission for unstable angina, hospital admission for heart failure, o

72 ss the effect of angiography on mortality in unstable angina, incorporating the results of additional

73 gible patients were older than 18 years with unstable angina, non-ST segment elevation myocardial inf

74 l infarction, stroke, hospital admission for unstable angina, or coronary revascularisation.

75 dial infarction, stroke, hospitalization for unstable angina, or coronary revascularization.

76 l infarction, stroke, hospital admission for unstable angina, or coronary revascularization.

77 dial infarction, stroke, hospitalization for unstable angina, or coronary revascularization.

78 and non-fatal stroke, hospital admission for unstable angina, or hospital admission for heart failure

79 oronary artery disease, history of stable or unstable angina, previous multi-vessel percutaneous coro

80 , death, reinfarction, rehospitalization for unstable angina, repeat coronary revascularization (targ

81 events, including 141 MIs and 84 episodes of unstable angina.

82 ns exist regarding the use of angiography in unstable angina.

83 hemic stroke, transient ischemic attack, and unstable angina.

84 ups and do not include subgroup analysis for unstable angina.

85 tion, stroke, coronary revascularisation, or unstable angina; key secondary endpoint was the composit

86 known reactivity to produce (hydrolytically unstable) anhydrides from carboxylic acids in water.

87 stabilization of the pyrazine (Pz) anion, an unstable anion in isolation due to its neutral counterpa

88 has a well-documented record of stabilizing unstable anions, little is known about halogen bonding's

89 structurally related to etnangien, a highly unstable antibiotic from Sorangium cellulosum that is al

90 Amiclenomycin (ACM) is a chemically unstable antibiotic with selective activity against Myco

91 ed invariant T (MAIT) cells are activated by unstable antigens formed by reactions of 5-amino-6-D-rib

92 everages, but protein-based nanocapsules are unstable around the isoelectric point of protein.

93 The inference that p53 was unstable as a heteromeric p53(wt)/p53(V172F) complex was

94 if they had a history of life-threatening or unstable asthma.

95 Although fused proteoliposomes became unstable at elevated SNARE concentrations, releasing the

96 bias and publication bias, and particularly unstable at follow-up.

97 al native states of globular proteins become unstable at low temperatures, resulting in cold unfoldin

98 r, the (SapA tetramer + iPOPC) complexes are unstable at neutral pH and convert, over a period of hou

99 The iron-bound polysulfides were unstable at physiological glutathione concentrations and

100 emperature solutions of pyridine but becomes unstable at room temperature, gradually converting to th

101 s are not correlated with cell shape and are unstable at the time scales of cell expansion.

102 we observed increased expression of SMILR in unstable atherosclerotic plaques and detected increased

103 rlap distances smaller than chemically soft, unstable atoms.

104 4+/CD24- cancer cells are genetically highly unstable because of intrinsic defects in their DNA-repai

105 in foci, which is a signature of potentially unstable behavior.

106 opper(I) is fully compatible with the highly unstable beta-lactam ring of carbapenems and that the tr

107 Unlike the unstable black phosphorous, another two-dimensional grou

108 haracterized by deregulated angiogenesis and unstable blood vessels.

109 ith higher fracture risk because of widened, unstable bones, independently of BMD.

110 (2D), and using pacemaker in the presence of unstable bradycardia or high-grade arteriovenous block i

111 D), and using a pacemaker in the presence of unstable bradycardia or high-grade arteriovenous block w

112 emosensory reflex activation also results in unstable breathing with apnoeas.

113 abolished the rhythm and replaced it by slow unstable bursting.

114 ng) and Ca(2+) destabilizing (arrhythmogenic unstable Ca(2+) signalling) factors.

115 les produced in the presence of C1 contained unstable capsids that lacked associated electron density

116 An unstable carotid plaque at risk of stroke is characteriz

117 NA expression in patients with stable versus unstable carotid plaque.

118 miRNAs of clinical interest in patients with unstable carotid stenosis at risk of stroke.

119 n glycolysis in an aldol condensation of the unstable catabolites glyceraldehyde 3-phosphate and dihy

120 s of many fungal pathogens comprise distinct unstable chromosomes called dispensable chromosomes (DCs

121 odel to study human circadian disorders with unstable circadian rhythm phases.

122 able states (stem and differentiated) via an unstable (committed) state.

123 therefore lead to transitions from stable to unstable community states.

124 indicate that early visual cortex is highly unstable compared to higher-level visual regions which a

125 ized by neutral donor ligands are relatively unstable compared to those stabilized by adsorbed metal

126 ally, in detergent the GluA2-A793F formed an unstable complex with CNIIH3 but in the membrane the Glu

127 have been made to stabilise this relatively unstable compound.

128 ss, anthocyanins are highly hydrosoluble and unstable compounds.

129 ice discharge and causing advance towards an unstable configuration followed by abrupt retreat, in a

130 homozygous familial hypercholesterolemia and unstable coronary artery disease requiring revasculariza

131 S (Invasive Versus Conservative Treatment in Unstable Coronary Syndromes) trial compared early invasi

132 ition-reductive elimination mechanism via an unstable Cu(III) intermediate is energetically more feas

133 f-life of (225)Ac, assuming instant decay of unstable daughter nuclides.

134 xploiting aoQM in synthesis is that they are unstable (DeltaG > 30 kcal/mol), precluding their format

135 TAOK2 depletion results in unstable dendritic protrusions, mislocalized shaft-synap

136 However, the difficulty in forming the unstable diazo compound partner in a mild fashion has hi

137 asthmatics who smoke cigarettes may develop unstable disease and neutrophilic infiltration of the ai

138 profiles support the notion that this is an unstable disordered precursor phase, which conceivably c

139 evelopment of chemically stable analogues of unstable DNA lesions enables accurate study of polymeras

140 d in human embryonic kidney (HEK) cells, was unstable due to degradation by proteasome.

141 -rich alloy, we found that the arc operation unstable due to frequent sticking between two molten ele

142 tumors progressively become more genetically unstable due to increased chromosomal aneuploidy and mor

143 Toroidal droplets are inherently unstable due to surface tension.

144 Electrokinetic instability refers to unstable electric field-driven disturbance to fluid flow

145 ntrinsically low electronic conductivity and unstable electrochemistry lead to poor cycling stability

146 n model comparison indicated that in such an unstable environment, reinforcement learning parameters

147 bifunctional enzyme that converts the highly unstable epoxide intermediate LTA4 into LTB4, a potent l

148 The unstable expansion of some STRs was associated with vari

149 kinetics are unusual, permitting only short, unstable F-actin filaments.

150 lines as precursors for the generation of an unstable family of diazo compounds using flow UV photoly

151 on followed by N-N bond formation, producing unstable five-membered ring intermediates that spontaneo

152 th renal failure who are too hemodynamically unstable for intermittent hemodialysis.

153 , Envs progress at isolate-specific rates to unstable forms that are sensitive to antibody neutraliza

154 ree but instead occupied by easily digested, unstable, "fragile" nucleosomes.

155 ely disassembling preprepared hydrolytically unstable frameworks and then reassembling the resulting

156 p-rDNA dominant progenitor were meiotically unstable, frequently switching to co-dominance.

157 urthermore, patients exhibit resting tremor, unstable gait, and impaired balance, which may be associ

158 itute a suitable system for encapsulation of unstable garlic active compounds and the encapsulation o

159 adversely affected by interface disorder and unstable gating.

160 satile expression of Gata2 suggests a highly unstable genetic state in single cells concomitant with

161 ion repair, much research has focused on the unstable genomic phenotype of BRCA1/2 mutant cells manif

162 o obtain a snapshot of the thermodynamically unstable glass colors.

163 mation, leading to cyclic responses that are unstable (hardening or softening) and history-dependent.

164 n of 18 boronic acids, many widely viewed as unstable, have been studied by NMR and DFT.

165 high- or low-status position in a stable or unstable hierarchy and were then exposed to a social-eva

166 interview performance, but high status in an unstable hierarchy boosted stress responses and did not

167 Networks that combine an unstable high-gain excitatory population with stabilizin

168 When the hierarchy is unstable, high status actually exacerbates stress respon

169 ntal conditions under anesthesia may lead to unstable homeostatic conditions in rodents and therefore

170 n the past year) experienced homelessness or unstable housing, and 57.9% (50.5-65.2) had a history of

171 Three housing stability patterns (unstable housing, stable housing, and rare institutional

172 assium azide, cyanate, and bromide) to yield unstable hypervalent iodine(III) compounds, PhIX2 (X = (

173 sis is caused by the clonal production of an unstable immunoglobulin light chain (LC), which affects

174 nthetic thiolate-bound ferric porphyrins are unstable in air unless the axial thiolate ligand is ster

175 y reactive organic radical that is otherwise unstable in aqueous media.

176 ike clinical virus, this genome proved to be unstable in cell culture; however, propagation of intact

177 ancer-derived PC3 cell line is metabolically unstable in cells because its N-terminal tryptophan targ

178 tein is stable in embryonic cells but highly unstable in differentiated cells.

179 se folding intermediates are predicted to be unstable in either an aqueous or a hydrophobic environme

180 , such as wake-sleep onset times, can become unstable in humans, and we present a unique mouse model

181 MRE11 is highly unstable in PTEN-deficient cells but stability can be si

182 rmed by chemical hydrolysis and, hence, also unstable in sewers.

183 generated from molecules that are inherently unstable in solution and in the solid state.

184 )Mn, and furthermore that (52)Mn-DOTA may be unstable in vivo whereas (64)Cu-DOTA appears suitable fo

185 l stem cells (hMSCs) is poorly organized and unstable in vivo.

186 ting previous reports that this substance is unstable in wine and must.

187 ot necessarily differentiate morphologically unstable (inflammatory) from stable (noninflammatory) at

188 In this limit, disk-shaped membranes become unstable, instead forming structures with scalloped edge

189 e calyx surrounding type I hair cells causes unstable intercellular K(+) concentrations, altering the

190 ate (1MOI3M) from I3M involves the predicted unstable intermediate 1-hydroxyindol-3-ylmethyl glucosin

191 could rapidly reduce the highly reactive and unstable intermediate generated upon radical interceptio

192 ASD show fewer neural transitions due to an unstable intermediate state, and these infrequent transi

193 of transcription factors (i.e. removing the unstable intermediate states), and that crowding by larg

194 We also discovered an unstable, intermediate-length RNA from the SMALL SCP1-LI

195 This transformation involves two unstable intermediates and a sequence of unusual reactio

196 ging synthetic requirements that incorporate unstable intermediates and are therefore highly irreprod

197 n K antagonist therapy can be complicated by unstable international normalized ratio values and patie

198 This indicates unstable intratumoral lineage relationships between CD27

199 corrosion mechanism, where the formation of unstable Ir(>IV) species is hindered.

200 We conclude the ability to move when unstable is the key developmental improvement to balance

201 sical properties of IK,L were affected by an unstable K(+) equilibrium potential (Veq K(+) ).

202 g solve times to complete and often leads to unstable kinetic model predictions.

203 on the nonspecific interactions of multiple unstable lanthanide chelates and nonantenna ligands with

204 on the nonspecific interactions of multiple unstable lanthanide chelates and selected chemicals with

205 tests, PP-GLMs estimated from data are often unstable, leading to divergent firing rates.

206 ns can store internally the otherwise highly unstable liquid native silk for several months and witho

207 /ZFC3H1 in nuclear surveillance of naturally unstable lncRNAs to prevent their accumulation, transpor

208 confirmed that TMEM175 deficiency results in unstable lysosomal pH, which led to decreased lysosomal

209 of these bursts indicate the presence of an unstable, magnetically regulated accretion mode, which i

210 ng results indicate that the retreat becomes unstable (marine ice-sheet instability) and thus acceler

211 Patients were excluded for unstable medical or psychiatric illness, including depen

212 es 130 and 131 and generated a heterodimeric unstable metabolite TSLP (29-130 + 131-159).

213 stability within the traditionally thermally unstable metallic state.

214 and amphibian eggs are a meshwork of short, unstable microtubules maintained by autocatalytic nuclea

215 and showed that the system is already in an unstable monopoly state in which growth of middle sized

216 These unstable MTs act as cargo traps, leading to ectopic accu

217 resent a case of the successful treatment of unstable, multivessel coronary artery disease in a child

218 mA cm(-2) ) for Li and even for notoriously unstable Na metal anodes.

219 teraction patterns but can also overcome the unstable nature of interaction patterns.

220 However, a major aspect of its unstable nature was attributed to its antiaromatic chara

221 not explored significantly because of their unstable nature.

222 t high frequencies in genes with overlapping unstable ncRNAs (CUTs), so limiting the availability of

223 Many animal bodies are inherently unstable, necessitating corrective locomotion to maintai

224 tals via the stabilization of a mechanically unstable, negative stiffness state of a martensitic allo

225 However, feedback creates the potential for unstable network responses.

226 osslink preferentially to mRNAs, rather than unstable non-coding RNAs.

227 However these alginate gels are mechanically unstable, not permitting their use as scaffolds to engin

228 f macrophages with N15m1, which expresses an unstable nsp15, or N15m3, which expresses a catalysis-de

229 However, certain variants were unstable once in the crossover dimer conformation, and c

230 s of these oftentimes incongruently melting, unstable or metastable materials.

231 this setup for analysis of, e.g., reactive, unstable, or mass-limited compounds.

232 Furthermore, both oxides are unstable outside the O2 atmosphere, indicating the prese

233 that suggested spiking representations were unstable over time.

234 genetic architecture of a subset of genes is unstable over time.

235 ngth p19(Arf) and N-terminally truncated and unstable p15(smArf) ("small mitochondrial Arf") initiate

236 to restore the function of conformationally unstable p53 cancer mutants, to the development of poten

237 and pending events; when contingencies were unstable, past and present coding persisted, but predict

238 al bleeding, particularly in hemodynamically unstable patients and in cases with suspected lower gast

239 Delayed canalicular repair in unstable patients did not lead to poor results.

240 ts may form on Earth and how a terrestrially unstable phase-like bassanite can persist at low-water a

241 cesses are highly disfavored when generating unstable phenyl and primary alkyl radicals.

242 ith concomitant formation of benzene from an unstable phosphorus(V) intermediate, yielding (C5 Me5 )2

243 ely including evidence that the detection of unstable plaque can change patient management and improv

244 d toward cellular targets that are unique to unstable plaque can serve as a powerful tool for identif

245 ry arteries are most often due to rupture of unstable plaque resulting in myocardial infarction.

246 ered by the inaccessibility of intrinsically unstable poly-beta-ketones for in vitro studies.

247 Our evaluation showed that the presence of unstable population markers in the model did not decreas

248 perturbed and the clock becomes dramatically unstable, presenting a unique behavioral phenotype unlik

249 Pih1 is an unstable protein and tends to aggregate when expressed a

250 Fitness constraints prevent the emergence of unstable protein evolutionary intermediates, thereby enf

251 s in skipping of exon 7 and production of an unstable protein isoform, SMNDelta7.

252 Gid4 is also a metabolically unstable protein.

253 vides the highest precision in timing for an unstable protein.

254 in and provides evidence that curcumin is an unstable, reactive, nonbioavailable compound and, theref

255 Reduction of the unstable red solid with Cs metal produces the dianion of

256 During sliding, Chd1 generates unstable remodeling intermediates that spontaneously rel

257 The stochastic frameshift of the unstable repeat DNA in a subset of BAC-expressing neuron

258 Inherited diseases caused by unstable repeated DNA sequences are rare, but together r

259 lications because the patient may be acutely unstable, requiring prompt intervention, often by a prac

260 ding hypertension in which a proteolytically unstable RGS2 mutant has been reported.

261 be resolved accurately despite conditions of unstable rundown.

262 multimeric and aggregated complexes with an unstable secondary structure.

263 c point stimulation, occasionally leading to unstable, self-terminating tachyarrhythmias.

264 , current abuse, intellectual disability, or unstable serious physical illness.

265 ts after which single mode operation becomes unstable, signaling multimode oscillatory dynamics, (2)

266 We identified both very stable and highly unstable signatures, as well as signatures that previous

267 The groups were summarized as 'unstable' sleepers (cluster 1, n = 41) and 'stable' slee

268 g processes due to their high reactivity and unstable solid electrolyte interphase (SEI).

269 od was developed for detecting many of these unstable species without affecting other blood/blood pla

270 ift when present, and automated filtering of unstable spectral features, particularly across thousand

271 In all cases, haploidy was shown to be an unstable state, so that cultures of mammalian haploid ce

272 and may lead to memory effects and alternate unstable states.

273 ticles with nontrivial and thermodynamically unstable structures.

274 Consensus clustering showed unstable subtype and principal component analysis (PCA)

275 al noncanonical mRNA isoforms are relatively unstable suggests that the production of non-stop and in

276 This initial oxidation generates an unstable sulfenic acid intermediate that is quickly conv

277 Sucrose esters induced an unstable system after gastric conditions leading to coal

278 the first isocyanide analogue of the highly unstable Ta(CO)6 and represents the only well-defined ze

279 rosatellite expansion diseases are caused by unstable tandem repeats of 3-10 nucleotides that become

280 ude nutrients per pulse) was relatively more unstable than community receiving multiple resource puls

281 y, learning immediately after training is so unstable that it can be disrupted by subsequent new lear

282 y at high concentrations and were especially unstable, the reactions proceeded via a "dead-end" polym

283 uggest that FtsN lacking a disulfide bond is unstable, thereby making this disulfide critical for fun

284 of locomotion, swimming preferentially when unstable, thus restoring preferred postures.

285 The Th-Bi combination was too unstable to isolate, underscoring the fragility of these

286 , especially those used as therapeutics, are unstable to storage and shipping temperatures, leading t

287 e {[Cu(I)]-C6F5}(-) and [Cu(III)](C6F5)(OPh) unstable toward reductive elimination to [Cu(I)](solvent

288 Cells derived from genomically unstable tumors exhibit evidence for a partially activat

289 ry passive state except the thermal state is unstable under a weaker form of reversibility.

290 le sites (CFSs) are genomic regions that are unstable under conditions of replicative stress.

291 itus caused HD cells to become directionally unstable under dark conditions without affecting the ani

292 in patients with coronary artery disease and unstable ventricular tachyarrhythmias.

293 and the sediment transport capacity of such unstable water is not well understood.

294 The MI leads to a growth-decay cycle of unstable waves and is therefore related to Fermi-Pasta-U

295 describe growth and decay of modulationally unstable waves in conservative systems.

296 cells, indicating that the mutant protein is unstable when naturally expressed.

297 quences, in Saccharomyces cerevisiae, become unstable when topoisomerase I (Top1) is disrupted.

298 At these pressures phosphine is unstable with respect to decomposition into the elementa

299 The hypothetical parent phase Bi4O4Cu2Se3 is unstable with respect to its charge-neutral stoichiometr

300 guest-free CMOF-5 structure is energetically unstable, with either the achiral conventional structure

301 in the polyubiquitin gene is evolutionarily unstable within and between yeast species, and that this