ライフサイエンスコーパス: unsuitable

1 other CE morphologic imaging modalities are unsuitable.

2 addition to making some anti-codon sequences unsuitable.

3 ot have (18)F-FDG avidity or are technically unsuitable.

4 ms while iodine-promoted cyclizations proved unsuitable.

5 Anti-microtubule cycle blocks would also be unsuitable.

6 recombinant proteins may be unaffordable or unsuitable.

7 an optimal donor/recipient matching is often unsuitable.

8 an optimal donor/recipient matching is often unsuitable.

9 peratures where this calibration approach is unsuitable.

10 misclassified patients, 128 became medically unsuitable, 35 died, and 26 became too sick to transplan

11 th removal codes of "too sick" or "medically unsuitable." A total of 44 388 patients were included; 4

12 raditional sequence alignment methods become unsuitable and infeasible.

13 the literature method for their preparation unsuitable and present an alternative synthesis.

14 conditions typically considered suitable to unsuitable and using vocal cues presented during two tim

15 t the assay used to reach this conclusion is unsuitable, and that promoter-bound, active Gal4 is inde

16 ding the presence of records in climatically unsuitable areas as a result of repeated introduction.

17 r destabilized in such a way as to render it unsuitable as a crystal growing system.

18 at sample heterogeneity makes RNASeq on PBMC unsuitable as a first-step method for screening biomarke

19 This test is unsuitable as a screening tool for gonorrhea.

20 at models, (11)C-JNJ-42491293 was considered unsuitable as a specific PET ligand for in vivo imaging

21 essure, hippocampal apoptosis), rendering it unsuitable as a therapeutic approach to chronic spinal i

22 Although unsuitable as a therapeutic due to M(2) receptor cross-r

23 thine decarboxylase activity was found to be unsuitable as an alternative to PCR identification, disp

24 nearly all have properties that render them unsuitable as drug candidates.

25 inally, they render themselves nutritionally unsuitable as hosts for enemies that require LA for thei

26 nsidered to be economically and ecologically unsuitable as it required the destruction of the yew tre

27 viral antigenicity, which made these mutants unsuitable as vaccine candidates.

28 liquids [emim][AlCl4] and [emim][Al2Cl7] are unsuitable, as counterion exchange and arene nitration c

29 containing immunochemotherapy was considered unsuitable because of coexisting cardiac disease.

30 testing, two potential LRKD were considered unsuitable because of the detection of stage I ("simple"

31 Americans are not more frequently medically unsuitable, but that the divergence in rates of live kid

32 We show that pyridine boronic acids are unsuitable, but they can be halogen-modified at the 2-po

33 This makes them unsuitable candidates for existing 3D-QSAR methods and h

34 nts positive for HIV were once thought to be unsuitable candidates for kidney transplantation, their

35 The three patients who were unsuitable candidates for OLT died after rewarming.

36 d reduced graft function who were considered unsuitable candidates for PRB (4.2% of all renal transpl

37 phases of drug development, thereby enabling unsuitable candidates to be eliminated from consideratio

38 ychiatric screening procedures to select out unsuitable candidates, and by providing access to psycho

39 have been in response to the strong flow and unsuitable conditions.

40 used host ants to be replaced by similar but unsuitable congeners, explaining the extinction of Europ

41 paranasal sinuses may be due to selection of unsuitable CT windows.

42 heir conclusions are overstatements based on unsuitable data and inappropriate analyses.

43 y reasons for nondonation (n=1,050) included unsuitable donor health (43.1%) and recipient-based caus

44 .1% unassessed, 30.4% medically unfit, 16.9% unsuitable due to age, 3.1% psychologically unfit and 1.

45 Women were more likely to be reported as unsuitable due to age, medically unfit and declined, and

46 ases procured for transplantation are deemed unsuitable due to concerns about graft quality and the a

47 However, such approach proved to be unsuitable due to the complexity of the obtained composi

48 to platforms that were previously considered unsuitable due to their large losses.

49 .g. CYTB gene, for species quantification is unsuitable, due to a fivefold inter-tissue variation in

50 These include ineffective pathways of care, unsuitable environments, inadequate resources and staffi

51 MRI) contrast agents (CAs) are suboptimal or unsuitable, especially at higher magnetic fields (>1.5 T

52 Three patients were deemed medically unsuitable following surgical inspection, 56 patients di

53 ver, this method of analysis would likely be unsuitable for a high-throughput clinical microbiology l

54 ge coils (at least a centimeter in diameter) unsuitable for a microimplant.

55 1 and 18 months old) were worked up but were unsuitable for ABO-incompatible transplantation because

56 Alteration of the CTG codon to render it unsuitable for acting as a translation initiation site d

57 ecruitment/post-recruitment mechanisms being unsuitable for activating gene expression under these co

58 but who harbor potentially aggressive tumors unsuitable for active surveillance.

59 ignment for single-end reads, which makes it unsuitable for alignment of longer reads where indels ma

60 xercise performance, but current systems are unsuitable for ambulatory use.

61 er, their low frequency (<100 Hz) makes them unsuitable for amplification in birds and mammals that h

62 ates were cleaved by cathepsins, making them unsuitable for analysis of complex cellular systems, the

63 ties of porphyrins, many of these assays are unsuitable for analysis of the catalytic properties of C

64 reted at picomolar concentrations and may be unsuitable for analysis using conventional SPME sorbent

65 , making them susceptible to degradation and unsuitable for applications requiring cleavage at elevat

66 re changes in the few kPa range, making them unsuitable for applications such as heart-rate monitorin

67 Brucella agar supplemented with taurine was unsuitable for B. wadsworthia beta-lactamase testing.

68 the FVB strain, suggesting the background as unsuitable for behavioral analysis.

69 bility and are compute intensive making them unsuitable for big data and high-throughput environments

70 n 62 cases (4.9%): more complex CHD that was unsuitable for biventricular repair, leading to unplanne

71 degrees and 2 degrees alkylnitrene complexes unsuitable for C-H amination.

72 ring therapeutic enhancement of this process unsuitable for cancer treatment.

73 to a critical chain length that soon becomes unsuitable for catalysis by SSI and hence cannot be elon

74 Though found to be unsuitable for cation determinations, the SCGD-RIC instr

75 However, such inorganic photodetectors are unsuitable for certain applications because of their hig

76 t are expensive, often poorly tolerated, and unsuitable for certain patient populations.

77 ive; no symptomatic brain metastases; deemed unsuitable for chemotherapy because of poor (>/=2) Easte

78 Patients with NSCLC who are deemed unsuitable for chemotherapy could be given erlotinib.

79 compound-specific isotope analysis (CSIA) is unsuitable for chlorinated compounds such as trichloroet

80 For a variety of reasons, many are unsuitable for clinical practice.

81 molecular level, and potentially render them unsuitable for clinical use in multiple recipients.

82 extracted DNA is of poor quality and may be unsuitable for CN assessment, thus representing a missed

83 changes that are large enough to render them unsuitable for coffee farming, in the absence of signifi

84 Multiple-day diet records can be unsuitable for cohort studies because of high administra

85 hydrocarbon formation renders this approach unsuitable for commercialization.

86 hanged after 3 days of storage making the CW unsuitable for consumption.

87 children who are spectacle noncompliant and unsuitable for contact lens wear.

88 ty of some algal strains to thrive in waters unsuitable for conventional crop irrigation such as sali

89 -income areas and marginal habitats that are unsuitable for crop production.

90 ad biopsy-proven oesophageal cancer that was unsuitable for curative treatment, symptomatic dysphagia

91 n expressed in Escherichia coli proved to be unsuitable for detailed structure-function studies.

92 virus showed that many diagnostic tests were unsuitable for detecting the novel virus isolates.

93 wth tests, which are both time consuming and unsuitable for detection of a mixture of organisms.

94 the use of purely instrumental techniques is unsuitable for detection of low levels of gallium in bio

95 narrow-spectrum agents are typically deemed unsuitable for development because of intrinsic limitati

96 hibitor of acetylcholine esterase (AChE) and unsuitable for development.

97 lood-brain barrier permeability and thus are unsuitable for diseases of the brain.

98 of wHTH domains, resulting in a conformation unsuitable for DNA binding.

99 , and had previously either received or were unsuitable for docetaxel.

100 tories from closed-cleft receptor structures unsuitable for docking.

101 of domestic livestock, with species that are unsuitable for domestic livestock grazing.

102 their improved performance, they are however unsuitable for early detection of cancer biomarkers or t

103 If the patient's anatomy was unsuitable for endovascular graft repair, standard open

104 unlike LUV, are metastable and consequently unsuitable for equilibrium thermodynamic measurements.

105 These inpatient algorithms are unsuitable for estimating stroke incidence because of lo

106 ul, these are often costly, nonspecific, and unsuitable for evaluating programmatic interventions.

107 Bs), whereas low-affinity binders (LABs) are unsuitable for evaluation.

108 e absence of any significant changes make it unsuitable for examining response to treatment in this s

109 methods for monitoring folding in vitro are unsuitable for experiments in vivo or in other complex m

110 her familiar nor coherently ordered and thus unsuitable for facilitating memory in this sense.

111 owth is very slow and highly variable and so unsuitable for fast high throughput anti-aggregation dru

112 ing, tedious, expensive, less sensitive, and unsuitable for field situations.

113 perhexiline analogues 6a-j were found to be unsuitable for further development, as they retained a p

114 P-glycoprotein liability makes this scaffold unsuitable for further development.

115 derate oral bioavailability made this series unsuitable for further development.

116 nsense-mediated mRNA decay (NMD) making them unsuitable for gene targeting applications.

117 licitly and with ad hoc methods, making them unsuitable for general motif searches.

118 variety of experimental expertise and so is unsuitable for genome-scale analysis.

119 le of a large watershed, it was judged to be unsuitable for global scale simulations due to the high

120 However, the current methods are unsuitable for growing single crystals of these oftentim

121 other being carbohydrate-deficient, which is unsuitable for growth.

122 suggesting that their micro-environments are unsuitable for haematopoietic differentiation.

123 ively large volumes of solvents, making them unsuitable for high-throughput analysis.

124 on of MS/MS fragmentation, making these tags unsuitable for high-throughput MALDI-TOF/TOF MS analysis

125 eful, vaccines presently used in animals are unsuitable for human use.

126 Vaccines currently used in animals are unsuitable for human use.

127 In contrast, we found it unsuitable for immunofluorescence applications in brain.

128 found inhibition by NADP(+) makes the enzyme unsuitable for in vivo applications.

129 ameras and high powered microscopes which is unsuitable for in vivo imaging and diagnosis.

130 , in many situations not cost-beneficial and unsuitable for industrial grade scale-up, this study acc

131 in these elderly patients with AML who were unsuitable for intensive chemotherapy was manageable and

132 IOV-121 were >or= 65 years of age and deemed unsuitable for intensive chemotherapy.

133 an EW SPT response <2 mm at entry) and were unsuitable for intervention.

134 nd PS at low calcium concentration, they are unsuitable for intracellular use.

135 s) are useful for analyzing samples that are unsuitable for isotopic labeling but are less accurate.

136 ure or cut from a whole corneal graft button unsuitable for keratoplasty.

137 igestion of unmodified ODNs, was found to be unsuitable for ladder sequencing ODNs with both termini

138 1E2 antigen is the reliance on GNA, which is unsuitable for large scale-up and global vaccine deliver

139 However, this method is currently unsuitable for large-scale deployment and focus has inst

140 The probands were from families unsuitable for linkage because of family size.

141 xisting protocols for purification of Sr are unsuitable for lipid matrix.

142 limited to photon wavelengths below 900 nm, unsuitable for long distance communication, and suffered

143 elated isolates, suggesting that PFGE may be unsuitable for long-term typing of strains involved in e

144 g a marker based on 8bp deletion in BADH2 as unsuitable for MAS in rice cultivars under study.

145 drug capable of eliminating hypnozoites, is unsuitable for mass administration, an alternative drug

146 omised animals, rendered these murine models unsuitable for meaningful assessment of antibody-mediate

147 ich can give rise to inconsistent properties unsuitable for medical applications.

148 ns but suggest that self-rated health may be unsuitable for monitoring changes in population health o

149 o initial diagnosis, such assays have proven unsuitable for monitoring therapeutic efficacy owing to

150 ls with a few interacting components, and is unsuitable for multi-dimensional systems consisting of a

151 been successful extending access to patients unsuitable for myeloablation.

152 Because Medicare DRGs are unsuitable for obstetrics, pediatrics, and neonatology,

153 tats identified by all models that were also unsuitable for oil palm - a major threat to tropical bio

154 eceived previous docetaxel treatment or were unsuitable for or declined docetaxel; previous docetaxel

155 t of atrial fibrillation in patients who are unsuitable for or intolerant of drug approaches.

156 ere forms of coronary artery disease that is unsuitable for other forms of revascularization.

157 However, many sample preparation methods are unsuitable for PCR utilization in the clinical laborator

158 d is sparingly soluble in water rendering it unsuitable for pharmaceutical development.

159 ns that had been deliberately designed to be unsuitable for Phi-value analysis because they are struc

160 ithography and inkjet printing are currently unsuitable for POC applications due to issues of cost an

161 m time-consuming, costly, less accurate, and unsuitable for point-of-care (POC) diagnostics.

162 The Slaughter and Dezenberg equations are unsuitable for predicting body fat in 9-y-old African pr

163 uble intercellular adhesion molecule 1) were unsuitable for predicting early complications after live

164 d by this technological advancement, and are unsuitable for processing images acquired with rapidly i

165 using the SMD in combination with the SE are unsuitable for publication bias assessments and can lead

166 multiple reagents and washing steps and are unsuitable for real-time detection of analyte binding.

167 and that common cell culture media might be unsuitable for redox research.

168 rarily sampled data distributions, which are unsuitable for reliable mechanistic inferences.

169 erparameterized and therefore, in principle, unsuitable for representing any data--those models are c

170 banked seeds from those populations will be unsuitable for restoring them.

171 timal salvage strategy and identify patients unsuitable for retreatment with FCR, we examined the sur

172 ), 525 patients with critical limb ischaemia unsuitable for revascularisation were enrolled from 171

173 for irreversible chemistry and are typically unsuitable for reversible applications, theoretical proc

174 The lack of a bandgap makes bulk graphene unsuitable for room temperature transistors with a suffi

175 This renders LC x LC unsuitable for routine analysis.

176 or reproducibility and stability making them unsuitable for routine in vivo applications.

177 ng reads to a reference genome, and are thus unsuitable for samples with a partial or missing referen

178 conditions that may be considered by many as unsuitable for scientific research.

179 racy associated with the AGA tests make them unsuitable for screening purposes.

180 For ECD kidneys unsuitable for single use, dual kidney transplants (DKT)

181 mature brain, these approaches are generally unsuitable for soft, irregular, and heterogeneous tissue

182 ty, this method of fibronectin deposition is unsuitable for some types of research, including quartz

183 Consequently, a long glial process is unsuitable for spatial buffering, unless the axial space

184 trials of SBRT for patients with active HCC unsuitable for standard locoregional therapies were cond

185 178 patients with stable exertional angina, unsuitable for standard revascularization, were randomiz

186 ensive and prone to human error, making them unsuitable for standardized clinical diagnoses.

187 xpression, making standard phenotypic assays unsuitable for strain characterization.

188 een BKV-TAg and Ku86, but makes the antibody unsuitable for studies of BKV large T-antigen in the hum

189 Xenopus and explant assays in the chick are unsuitable for studying instructive signals in neural in

190 ng pathogenesis is minor, the model has been unsuitable for studying the impact of antibodies on path

191 e patients (mean age 76.6+/-10 years) deemed unsuitable for surgery who underwent MitraClip treatment

192 ported favorable 1-year outcomes in patients unsuitable for surgery who underwent self-expanding tran

193 due to their location within the brain, are unsuitable for surgical resection and consequently have

194 NSCLC patients with brain metastases unsuitable for surgical resection or stereotactic radiot

195 le pharmacokinetic properties that render it unsuitable for systemic administration.

196 ctron bunch, such an electron-driven wake is unsuitable for the acceleration and focusing of a positr

197 y on optimal starting DNA, and are therefore unsuitable for the analysis of formalin-fixed paraffin-e

198 However, this renders these tools unsuitable for the analysis of large cosmopolitan cohort

199 However, GC/MS is unsuitable for the analysis of many conjugated steroids

200 have a shorter lifespan and NOD ES cells are unsuitable for the complex genetic engineering that is r

201 c A-ring substrate, however, was found to be unsuitable for the introduction of the requisite hydroxy

202 olymerization (DP) <50) species but appeared unsuitable for the largest polymers in the series due to

203 Others regard their methodology as unsuitable for the low-frequency conditions of quiet sta

204 Others regard this method as unsuitable for the low-frequency conditions of quiet sta

205 or the study of quantum systems and are also unsuitable for the low-temperature operation that is req

206 es suitable for quantum key distribution but unsuitable for the most general quantum key repeater pro

207 undergone bone marrow transplantation or be unsuitable for the procedure.

208 to be significantly worse, showing it to be unsuitable for the purpose of single-calibrant quantific

209 protein kinases, but these technologies are unsuitable for the study of kinase behavior in large num

210 es and the volumes required make them highly unsuitable for the testing of mouse platelets.

211 s, the shake-flask method, is antiquated and unsuitable for the testing of valuable and scarce drug c

212 antification of melanoidins were found to be unsuitable for their analysis in bread.

213 ow amounts of moisture makes them, a priori, unsuitable for their direct use as light harvesters in a

214 owever, LMB is toxic in vivo, which makes it unsuitable for therapeutic use.

215 that lose their identity over time could be unsuitable for therapeutic use.

216 loxP site by a single point mutation, proved unsuitable for this approach.

217 cm for women and > or = 102 cm for men) were unsuitable for this population because only 15 of 240 su

218 Neopentyl sulfate proved to be unsuitable for this purpose, since it was found to under

219 Although the b.End3 cells appear unsuitable for transendothelial permeability assessments

220 ceiving life-sustaining treatments are often unsuitable for transfer to home or community hospices.

221 from blood anticoagulated with citrate were unsuitable for transfusion because of platelet clumping.

222 of Canada classified as unsuitable or rather unsuitable for transmission.

223 usly refused for quality are not necessarily unsuitable for transplant and often show excellent outco

224 ytime within 72 hours; (III) Declined: lungs unsuitable for transplantation after EVLP.

225 ed after prolonged warm ischemia (WI) may be unsuitable for transplantation due to the risk of reperf

226 Sixteen human donor corneal tissues unsuitable for transplantation were used.

227 Nine human corneoscleral specimens unsuitable for transplantation were used.

228 ifty-four random human donor corneal tissues unsuitable for transplantation.

229 ssue cubes (ALTCs) using normal liver tissue unsuitable for transplantation.

230 n, and the most severely affected hearts are unsuitable for transplantation.

231 assess and rescue kidneys previously deemed unsuitable for transplantation.

232 are available, many of which have been found unsuitable for treatment of neuropsychiatric disorders f

233 patients with severe coronary artery disease unsuitable for treatment with standard revascularization

234 e-tension-induced microcavities, making them unsuitable for ultra-high-Q experiments.

235 endering them difficult to process and often unsuitable for usage.

236 t, ES-62, which as an immunogenic protein is unsuitable for use as a drug.

237 proximately 4-fold after injury, making them unsuitable for use as normalization genes in this study.

238 are expensive and/or invasive and therefore unsuitable for use as screening tools, but a non-invasiv

239 oped in the 1940s and 1960s that were deemed unsuitable for use as therapeutic agents as a result of

240 xperimental compounds used preclinically are unsuitable for use in humans, due to associated toxicity

241 fonylureas tend to be restricted in scope or unsuitable for use in parallel synthesis.

242 ful for gene targeting in non-plant systems, unsuitable for use in plant systems.

243 raditional diagnostic methods that make them unsuitable for use in resource-limited settings, from ex

244 ither positrons or gamma-rays and are, thus, unsuitable for use with current nuclear imaging modaliti

245 ily convert into an alternative conformation unsuitable for vaccine purposes.

246 vious palliative surgical procedures, may be unsuitable for ventricular assist device implantation.

247 Fibrillation Patients Who Have Failed or Are Unsuitable for Vitamin-K Antagonist Treatment (AVERROES)

248 me and/or mild NPQ responses and were, thus, unsuitable for WABI-based monitoring.

249 ke risk in atrial fibrillation (AF) patients unsuitable for warfarin by 63% but does not increase maj

250 weapons, but the licensed anthrax vaccine is unsuitable for widespread public administration.

251 Because donor pancreata that are unsuitable for WOP can often be used successfully for II

252 Crystals of 1 and 4 were unsuitable for X-ray crystal structure determinations, b

253 what we conclude are microscopic aggregates unsuitable for x-ray crystallography.

254 -level framework were due to the adoption of unsuitable gene sets defined typically on the basis of t

255 rather than one reaction at a time, which is unsuitable given the size of genome-scale models.

256 st fragments), shade coffee, sun coffee, and unsuitable habitat.

257 ent of "most suitable", "less suitable" and "unsuitable" habitat was calculated for the baseline year

258 , and 327 (41.1%) had positive crossmatch or unsuitable human leukocyte antigens.

259 e-bnAb germline precursors and are therefore unsuitable immunogens to prime supersite-bnAb responses.

260 rgans from donors who would have been deemed unsuitable in earlier times.

261 s time-consuming, technically demanding, and unsuitable in many cell types.

262 Communication headsets were found to be unsuitable in simulation.

263 to target genes/genomic sequences are often unsuitable in such cases.

264 e chlorinated compounds (VOCls) and are thus unsuitable in systems designed for studies of such compo

265 used by a male to distinguish suitable from unsuitable mating partners through a simple logic.

266 humans, because previous studies used either unsuitable methods or paradigms to address this question

267 ques for analyzing miRs; however, the use of unsuitable normalizers might bias the results.

268 nd expanded, certain definitions have become unsuitable or ambiguous.

269 is very low with all of Canada classified as unsuitable or rather unsuitable for transmission.

270 In situations where liver biopsy is unsuitable or unavailable the white cell and platelet co

271 When vaginal dilation is unsuitable or unsuccessful, however, vaginal reconstruct

272 ients subject to ICOD were finally medically unsuitable organ donors.ICOD contributed to 24% of the 4

273 e of the system, and Monte Carlo methods are unsuitable owing to the fermionic sign problem.

274 s with low canopy cover typically considered unsuitable, resulting in aggregations of warblers in are

275 retrospective correction for injections with unsuitable signal levels without the necessity to repeat

276 systems, a two-class classification is often unsuitable, since it does not consider the unpredictable

277 on and 10% of pancreatic cancer making it an unsuitable single marker for diagnosis.

278 produce will drop most of their offspring on unsuitable sites; when the parameter is very large, larg

279 renal biopsies, until recently considered an unsuitable source of mRNA for microarray analysis, to in

280 e initially identified 527 records and after unsuitable studies were removed, our search yielded 148

281 etimes substantial, making autorefraction an unsuitable substitute for trial frame refraction.

282 Such defective genomes would certainly be unsuitable substrates for integration.

283 eding areas are separated from each other by unsuitable surroundings, and a stable population in a co

284 s are protected by a monolayer and thus seem unsuitable targets for coatomers.

285 n obtained from CPE parameters, following an unsuitable theory for the case of microbial-electrochemi

286 tly, antimalarials that were once considered unsuitable therapeutic agents have been revisited to imp

287 rotic drugs and any individuals deemed to be unsuitable to enter a research study (eg, known dementia

288 ngs indicate that the disulfides in DsbB are unsuitable to function as the oxidant of DsbA.

289 ents presenting with coronary artery disease unsuitable to further revascularization techniques and s

290 g proteins exploit noncovalent interactions, unsuitable to long-term studies, or genetic fusion to na

291 ponges can tolerate environments that appear unsuitable to many corals and with increased sedimentati

292 tis elegans and Drosophila melanogaster) are unsuitable to model CKDs.

293 required a large amount of memory, making it unsuitable to process reads from large genomes with comm

294 tic-alignment at low temperatures makes them unsuitable to study heat-sensitive membrane proteins lik

295 make the protected resource unattractive or unsuitable to the pests (push) while luring them toward

296 found in refugia: patchy, marginal habitats unsuitable to their nonnative competitors.

297 ing, is sensitive to propionate making it an unsuitable tracer to assess hepatic glycolytic, gluconeo

298 As existing fluorescence probes are unsuitable, we have designed membrane-permeable HMRef-be

299 females find some display sequences of males unsuitable, while others are accepted.

300 e great majority of stream segments would be unsuitable with high certainty, regardless of the climat