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1 ion mechanisms have remained largely elusive until now.
2 quences of this association remained elusive until now.
3 has not been available in full and in detail until now.
4 otential, but this goal has remained elusive until now.
5 t translation in vivo have been unattainable until now.
6  translation in cellulo has remained elusive until now.
7 alcium channels themselves have been unknown until now.
8 s tended to be unchanged over time, at least until now.
9 ation of the inner ring has remained unknown until now.
10 ccuracy remains a crucial but unsolved issue until now.
11 the limited structural information available until now.
12 ide in prostate cancer has not been reported until now.
13 ly reserved for amphiphilic (block) polymers until now.
14 valuated, the results have been inconsistent until now.
15 es to mass peaks have rarely been elucidated until now.
16 nery, of which the function remained elusive until now.
17        The reason for this is not understood until now.
18 ther differentiation, has remained elusive - until now.
19 led energy landscapes have not been reported until now.
20 nce for this shared pathway has been missing until now.
21 iation studies (GWAS) of cortical Abeta load until now.
22 e production time period from the late 1960s until now.
23 e replication, but the mechanism was unknown until now.
24 eted natural product, which remained unknown until now.
25 (MWCNTs) in aquatic vertebrates is available until now.
26 stence following viral clearance was unknown until now.
27 nts have not been functionally characterized until now.
28 ity was observed with the doses administered until now.
29 terotypic interactions remained inconclusive until now.
30 cle, although this has not been clearly seen until now.
31 tional gene regulation by lncRNAs identified until now.
32 lp of silyl groups but have been disregarded until now.
33 hat govern this in T cell subsets is unknown until now.
34 able B-cell responses have been unsuccessful until now.
35 o be monitored in vivo have been unavailable until now.
36 heir size, with the net impact being unclear until now.
37  reaction (photo-BHAS) have remained elusive until now.
38 ported for organic sodium-ion battery anodes until now.
39 associated mechanisms have not been explored until now.
40 r anthropogenic-biogenic interaction studies until now.
41 e genetic variation that has remained hidden until now.
42  mechanisms have not been fully demonstrated until now.
43  the NE has not been investigated thoroughly until now.
44 he highest recorded for any compound studied until now.
45                                              Until now 2D FTICR MS afforded only a moderate resolutio
46                                              Until now, 2D spectroscopy has been hampered by its reli
47                                              Until now a direct and quantitative measurement of the s
48 ered by the lack of experimental models, and until now, a mouse roseolovirus has not been identified.
49                                              Until now, a single E3 ligase complex (LUBAC), one speci
50                                              Until now, a single regulatory mechanism has been propos
51                                              Until now, acoustophoretic mobility has almost exclusive
52                            Unfortunately, up until now all methods for finding high scoring SNPs in a
53                                              Until now, all known rifampin-resistant vaccinia virus i
54 a light-sensing function for mammalian OPN5, until now an orphan opsin.
55                                              Until now, an investigation of the role of the perinucle
56 his class of variation has not been possible until now and their mutational dynamics are still poorly
57 e with accelerating carbon dioxide emissions until now, atmospheric carbon dioxide concentrations exh
58                      This supports the view, until now based on in vitro data, that terminally differ
59  study of intraplate faults has been limited until now, because intraplate earthquake recurrence inte
60 glucose and glucose 6-phosphate in milk have until now been dependent upon several time consuming and
61 c, superconducting and chiral materials have until now been limited to three degrees of freedom: spin
62 therefore largely unpredictable, and had not until now been present with any structural classificatio
63 opy performed in the electron microscope has until now been too poor to allow such a combination.
64 reactive and short-lived oxygen species, has until now been unknown.
65 tempts to improve immune reconstitution have until now been unsuccessful, underscoring the need for b
66 he development of vesicularity in magmas has until now been viewed (both thermodynamically and kineti
67 ies, but their evolutionary history has not, until now, been comprehensively explored.
68 ization process in small molecules that has, until now, been elusive.
69 ive genetic and physical map resources have, until now, been required to direct the sequencing effort
70 ual basal forebrain cholinergic neurons has, until now, been technically beyond reach due to their la
71                                              Until now, beta cells were generally regarded as a singl
72                                              Until now, both simplex and familial UHS-affected case s
73 nrichment has powered methylation proteomics until now, but the reliability, pan-specificity, polyclo
74 gen in SHG images was consistently addressed until now, cellular and tissue information included in T
75                                              Until now, charge-shift bonds have been previously ident
76 al charge deficit of AlO4(-) tetrahedra, but until now clustering has not been confirmed.
77                                     However, until now, colocalizing face-specific mechanisms in both
78        The earliest fossil echinoderms have, until now, come almost exclusively from North America an
79                                          Yet until now, cortical activity during REM sleep was though
80  form well-defined host-guest complexes, but until now cross-linked beta-cyclodextrin polymers have h
81                                              Until now, data comparing anger and aggression in female
82                                              Until now, descriptions of how light-adapted retinal cir
83 eads from these arrays has not been realized until now despite having great potential for studying ca
84                                              Until now, despite the absence of experimental evidence,
85 ssigned and reassigned cases fit this model, until now desulfurization of the synthetic gliotoxin ana
86                                              Until now, detailed comparisons were hampered by the sma
87                                              Until now, determination of the threshold required for t
88                                              Until now, determining absolute values also required mea
89                                              Until now, diagnosis has been mainly based on the presen
90                            To our knowledge, until now, dietary intake data have not been assessed fo
91                                              Until now, efforts to address this issue have been isola
92                                              Until now, efforts to enhance the performance of semicon
93                                              Until now, efforts to extend gestation using extracorpor
94                                              Until now, evidence for the oldest life on Earth focused
95                                              Until now, evidence for this bridging role was largely d
96                                     However, until now, few of these transporters have been biochemic
97 tudies of powerful accretion-disk winds have until now focused only on X-ray observations of local Se
98 ilene latifolia and papaya have been studied until now for the presence of evolutionary strata on the
99 avity, several approaches have been proposed until now for the quantum description of discrete geomet
100  achieved through functionalization have, up until now, found only systems where fluorescence is quen
101                                    Moreover, until now, genetic analyses have not been applied to bip
102 e in the vicinity of the Bloch points, which until now has been accessible only through micromagnetic
103 ce, detailed understanding of the subject up until now has been lacking, especially toward tuning the
104 w on multicomponent protease inhibition that until now has mainly relied on blockage of the active si
105 working on complex optimization problems but until now has not been directly observed in nature as a
106 he proinflammatory IFN-gamma cytokine, which until now has only been detected transiently in acute in
107  as a strategy for regenerative medicine but until now has only been shown in culture settings.
108 xamples to demonstrate how GUMBOS chemistry, until now, has been beneficial to the general area of ma
109 clinical application of temozolomide, which, until now, has been largely limited to glioblastoma.
110 ine rubrene for a singlet fission step that, until now, has not been convincingly observed.
111 roperties of domain walls under illumination until now have been accessible only to macroscopic studi
112 species on low-surface-area particles, which until now have been infeasible to characterize.
113                            Treatment options until now have revolved around interferon, limited in ef
114 step for the field of regenerative medicine; until now, histology and scanning electron microscopy ha
115                                           Up until now, however, only ferroelectric polymers have int
116                                              Until now, however, the impact of expanding seaport infr
117                                              Until now, however, the substantial electrostatic disord
118                                              Until now, HPABH4D has been regarded as a transient and
119 es have produced the most convincing results until now, including independent replication of the pred
120                                              Until now, international studies have primarily focused
121                    What has remained unknown until now is how the phosphodianion group influences the
122 he epicardium, a multipotent epithelium that until now is only established to normally generate cardi
123 t one factor that has not received attention until now is the possibility that study participants' re
124 the corresponding two-dimensional films, but until now it has been difficult, costly, and impractical
125  very early in the evolution of land plants, until now it has been unclear whether the established an
126 s-giant cores has successfully been modeled, until now it has not been possible to date their formati
127                                              Until now it has not been possible to determine whether
128                                              Until now it was not known whether GABA exerts its effec
129                                     However, until now, it could not be used for local ancestry infer
130                                              Until now, it has been assumed that enhanced spinogenesi
131                                              Until now, it has been reasonably assumed that specific
132                                     However, until now, it has been unclear how receptor binding trig
133                                              Until now, it was thought that ephrin-Eph signaling requ
134                                              Until now ITPA variants have only been associated with a
135                                     However, until now its molecular mechanism remained unclear.
136                                              Until now, its course in the chronic stage is less well
137                                              Until now, its disease-causing mechanism has remained un
138                                              Until now, KIT has been considered an oncogenic driver a
139                                              Until now lamellar gel (Lbeta) phases have been describe
140                   The sequential hypothesis, until now largely ignored, is discussed, and recent lite
141                                              Until now, left ventricular ejection fraction has been u
142 ide effects of childhood cancer therapy, but until now little has been known about the relationship b
143                                     However, until now little was known about visceral arches in earl
144                                              Until now, little has been known about the physiological
145                                              Until now, little information was available on how many
146 ypic diversity between individuals, however, until now, little molecular evidence has been provided.
147                                              Until now mapping of the tumor vasculature has been diff
148                                              Until now, measurement of diffuse scattering from protei
149                                              Until now, mechanisms involved in dopaminergic circuit f
150                                              Until now, mercuric chloride supported on carbon is used
151                                     However, until now modeling of the rotameric state of residues ha
152                                     However, until now, monitoring dendrite growth by MRI has been li
153                                           Up until now, most longevity pathways were discovered in in
154  probiotics in periodontal therapy; however, until now, most research has focused on lactobacilli pro
155                                              Until now, multiplex RPA assays have not been developed
156 thetase-I mutations cause X-linked CMT6, but until now, mutations in the recessive forms of disease h
157                                              Until now, network controllability has been characterize
158                                              Until now neural networks have not been capable of this
159                                     However, until now no convincing answer has been given to the que
160 tion for anomalous radar data on Europa, but until now no penitentes have been identified conclusivel
161                                              Until now, no clear data have been available on which is
162                                     However, until now, no coastal and marine planning process has ap
163 of methane-metabolizing microorganisms, but, until now, no compelling evidence has existed for methan
164                                     Notably, until now, no experimental model has been described to d
165                                              Until now, no experiments on Earth could selectively sup
166                                              Until now, no framework has been available to bridge thi
167                                              Until now, no in vitro method that fully converted the i
168                                     However, until now, no information concerning NPFF2 receptor phos
169                                              Until now, no live-cell studies on EBOV nucleocapsid tra
170                                           Up until now, no models exist that can predict the joint ef
171 le has remained an intriguing puzzle and, up until now, no molecular system has provided clear eviden
172                                     However, until now, no one has studied the motor cortex (MC) and
173                                              Until now, no perfect reaction route has been proposed f
174                                     However, until now, no realistic formulation has been described.
175 tromal structure of the cyt b6f complex had, until now, no reported function.
176                                              Until now, no signaling mechanisms originating within th
177                                              Until now, no site-of-metabolism models made use of regi
178                                              Until now, no structural information has been available
179                                              Until now, no studies have assessed the ecological cause
180 -cancer properties in vitro and in vivo; but until now, no study has focused on the role of SFN in HC
181                                              Until now, no systematic identification of lncRNAs has b
182                                              Until now, no technology compatible with use in unrestra
183                                     However, until now, no vertebrate animal model has tested the req
184                                              Until now, nonnative plant species were rarely found at
185                                              Until now, nonspherical polymersomes have only been cons
186     Artificial light-harvesting systems have until now not been able to self-assemble into structures
187 olutionary and epidemiological framework has until now not been available for influenza B viruses, de
188 cal quality and comparability assessment has until now not been demonstrated.
189                                              Until now, numbers of PARP inhibitors have been reported
190 s channel in prostate cancer (PCa) remained, until now, obscure.
191                                     However, until now only data from 10 patients with NEN were avail
192 ic stresses, namely salt and drought stress, until now only one transcription factor (TF) binding to
193                                              Until now, only 1 human VKORC1 mutation, p.Arg98Trp, is
194                                              Until now, only a few genes orthologous to mammalian imp
195                                           Up until now, only bacterial enzymes have been used in ther
196 all termites known from the Cretaceous have, until now, only been winged reproductives (alates and de
197                                     However, until now, only low-order, phonon-mediated, localized po
198                                              Until now, only Pseudoalteromonas luteoviolacea had been
199 gh molecular weight mixed disulfide adducts: until now, only Tg "adduct B" was identified as primaril
200                                              Until now PAC have not been chemically labeled with fluo
201                                              Until now PCCT has been plagued by strong artifacts when
202  promoter motifs present in circadian genes, until now PIFs have not been shown to affect the circadi
203                                              Until now, plant species response to climate change has
204                                              Until now, polymyxin resistance has involved chromosomal
205 titive nature of the Ae. tauschii genome has until now precluded the development of a reference-quali
206                                              Until now, protein-DNA assemblies have been used to orga
207                                              Until now, published monitoring studies have been local
208                                              Until now, QSAR/QSTR models have predicted ecotoxicity o
209                                              Until now, quantitative SF yield at room temperature has
210                                              Until now, qubits have been assessed primarily by random
211 n in 2-dimensional paper network assays, but until now, reagents have only been included as wet or dr
212 some eating disordered behaviors, which have until now received relatively little attention, have bee
213 its to miniaturization in insect brains have until now relied on information based on data collected
214  thus of great interest in this context, has until now remained unknown.
215  The importance of these lesions in ALL has, until now, remained unclear.
216 d the majority of wild flowering plants, but until now research on pesticide effects has been limited
217                                              Until now, Schizosaccharomyces pombe was known to use re
218                                              Until now, several controversies have arisen over the sp
219                                              Until now, several potential neurotransmitters or neurom
220            Although this dual dependence has until now severely complicated analysis of DCs from high
221                                     However, until now, single MFI nanosheets have been prepared usin
222                                              Until now, six different leukocidins have been described
223                                              Until now, studies on KHK inhibition with small molecule
224                                              Until now, studying how EBOV disseminates into and persi
225                                              Until now, success has been limited to several small mol
226 nowledge of aspects that were not well known until now, such as GPCR complex stoichiometry and stabil
227                                              Until now, such personalized medical approaches have lar
228                                              Until now, syndemic theory has been applied to comorbid
229                                           Up until now the coexistence of QKD with data has been limi
230  neurons with silver began in the 1800s, but until now the great resolving power of the laser scannin
231 stic role of SUMO proteases in model plants, until now the identity or the function of these regulato
232                                              Until now, the analytical framework for understanding th
233                                     However, until now, the biological relevance of the intraluminal
234                                              Until now, the building of this cache of data for Galaxy
235                                              Until now, the central links between somatosensory and b
236 inin (FHA), a surface-displayed adhesin, and until now, the consequences of this interaction were unk
237                                              Until now, the dbGaP controlled-access environment requi
238                                              Until now, the detailed enzyme mechanism and the molecul
239 -organic self-assembly approach in 2004/2005 until now, the direct synthesis of OMCs is still limited
240                                              Until now, the domains determining the chNHE1 receptor f
241                                              Until now, the Food and Drug Administration (FDA)-approv
242                                              Until now, the fossil record has not been capable of rev
243                                              Until now, the frequency and affinity of myelin-reactive
244                                              Until now, the function of the class 2 mutations was unc
245                                              Until now, the genetic mechanism has been unclear.
246                                              Until now, the identity of the main structural protein c
247                                              Until now, the initial quantum dynamics following photoe
248                                              Until now, the interacting effects of concussions and th
249 viduals was reported more than 10 years ago, until now, the main function of this transcription facto
250                                              Until now, the mechanism and effects of parasite protein
251                                              Until now, the mechanisms governing soil concentrations
252                                              Until now, the mechanisms underlying the effect of predi
253                                     However, until now, the neural code for time has not been compare
254                                              Until now, the oldest fossil records of New World monkey
255                                              Until now, the participation of CXCR7 in CXCL12-induced
256                                              Until now, the physiological relevance of PRR2 remained
257                                              Until now, the quantitative information about the fracti
258                                           Up until now, the quantitative reconstruction of thicknesse
259                                              Until now, the question if podocytes can be replaced by
260                                              Until now, the role of GBA for the formation of dynamica
261                                              Until now, the role of mast cells in the onset and incid
262                                              Until now, the structure of a Wbl protein has not been a
263                                              Until now, the use of gas chromatographic approaches to
264                                              Until now, the validity of these models has usually been
265 hyrolipomas seem to be a rare occurrence and until now their prevalence has only been reported in two
266                                              Until now, their preparation required strongly electroph
267                                     However, until now there has been no convincing candidate for the
268 s are referred to as 'non-magnetic', because until now there has been no evidence that they have a ma
269 cological and evolutionary implications, but until now there has been no way of observing dynamic fai
270                                     However, until now there was no direct evidence that the state of
271                                     However, until now there was no report of pathogenic mutations in
272                                              Until now, there has been little knowledge on oxidation
273                                              Until now, there has been no animal model to study JCV i
274 king memory for subsequent manipulation, but until now, there has been no demonstration of this capac
275 e limitations of current analytical methods, until now, there has been no procedure capable of detect
276                                              Until now, there have been 27,013 reported cases and 11,
277                                           Up until now, thermal events have been considered as the on
278 g copper homeostasis within plant cells, but until now they have been studied mostly in model plant s
279 most of the polar organic solvents, and thus until now, they were not considered suitable for electro
280                                     However, until now this approach has not been deployed to study l
281                                              Until now, this disease has been consistently associated
282                                              Until now, this reaction has been primarily the remit of
283                                              Until now, this role remained an untested prediction of
284                                              Until now, this technique has used exogenic and undefine
285                                              Until now, this widely accepted monotonic excitation ene
286                                     However, until now TMD-based lasing has been realized only at low
287 ion "Did we make the right choice in waiting until now to ask your consent?" three of 60 (5%) respond
288 f the bleeding score (BS) have been proposed until now to confirm diagnosis but not to predict clinic
289                                              Until now, too little attention has been focused on BC's
290 engineering and biomedical applications, but until now transformations have required external trigger
291                                              Until now, treatment ameliorating early brain injury fol
292                                              Until now, treatment options have been restricted to sur
293 ue for non-medical (social) indications, but until now very few patients with cancer have achieved pr
294 personal behavior, vitality forms have been, until now, virtually neglected in neuroscience.
295 or syntaxin 31-like genes in resistance that until now was not known.
296 ability of the adaptive immune system, which until now was thought to be mediated mainly by B cell an
297 ted trophic pyramid has been questioned, but until now, was not resolved empirically.
298                                              Until now, we could only superficially analyze this phen
299 vities are typical of certain helicases, but until now were shown for no other reverse gyrase.
300 ine release in the PFC has not been possible until now, when the validity of using the positron emiss

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