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1 ion mechanisms have remained largely elusive until now.
2 quences of this association remained elusive until now.
3 has not been available in full and in detail until now.
4 otential, but this goal has remained elusive until now.
5 t translation in vivo have been unattainable until now.
6 translation in cellulo has remained elusive until now.
7 alcium channels themselves have been unknown until now.
8 s tended to be unchanged over time, at least until now.
9 ation of the inner ring has remained unknown until now.
10 ccuracy remains a crucial but unsolved issue until now.
11 the limited structural information available until now.
12 ide in prostate cancer has not been reported until now.
13 ly reserved for amphiphilic (block) polymers until now.
14 valuated, the results have been inconsistent until now.
15 es to mass peaks have rarely been elucidated until now.
16 nery, of which the function remained elusive until now.
17 The reason for this is not understood until now.
18 ther differentiation, has remained elusive - until now.
19 led energy landscapes have not been reported until now.
20 nce for this shared pathway has been missing until now.
21 iation studies (GWAS) of cortical Abeta load until now.
22 e production time period from the late 1960s until now.
23 e replication, but the mechanism was unknown until now.
24 eted natural product, which remained unknown until now.
25 (MWCNTs) in aquatic vertebrates is available until now.
26 stence following viral clearance was unknown until now.
27 nts have not been functionally characterized until now.
28 ity was observed with the doses administered until now.
29 terotypic interactions remained inconclusive until now.
30 cle, although this has not been clearly seen until now.
31 tional gene regulation by lncRNAs identified until now.
32 lp of silyl groups but have been disregarded until now.
33 hat govern this in T cell subsets is unknown until now.
34 able B-cell responses have been unsuccessful until now.
35 o be monitored in vivo have been unavailable until now.
36 heir size, with the net impact being unclear until now.
37 reaction (photo-BHAS) have remained elusive until now.
38 ported for organic sodium-ion battery anodes until now.
39 associated mechanisms have not been explored until now.
40 r anthropogenic-biogenic interaction studies until now.
41 e genetic variation that has remained hidden until now.
42 mechanisms have not been fully demonstrated until now.
43 the NE has not been investigated thoroughly until now.
44 he highest recorded for any compound studied until now.
48 ered by the lack of experimental models, and until now, a mouse roseolovirus has not been identified.
56 his class of variation has not been possible until now and their mutational dynamics are still poorly
57 e with accelerating carbon dioxide emissions until now, atmospheric carbon dioxide concentrations exh
59 study of intraplate faults has been limited until now, because intraplate earthquake recurrence inte
60 glucose and glucose 6-phosphate in milk have until now been dependent upon several time consuming and
61 c, superconducting and chiral materials have until now been limited to three degrees of freedom: spin
62 therefore largely unpredictable, and had not until now been present with any structural classificatio
63 opy performed in the electron microscope has until now been too poor to allow such a combination.
65 tempts to improve immune reconstitution have until now been unsuccessful, underscoring the need for b
66 he development of vesicularity in magmas has until now been viewed (both thermodynamically and kineti
69 ive genetic and physical map resources have, until now, been required to direct the sequencing effort
70 ual basal forebrain cholinergic neurons has, until now, been technically beyond reach due to their la
73 nrichment has powered methylation proteomics until now, but the reliability, pan-specificity, polyclo
74 gen in SHG images was consistently addressed until now, cellular and tissue information included in T
80 form well-defined host-guest complexes, but until now cross-linked beta-cyclodextrin polymers have h
83 eads from these arrays has not been realized until now despite having great potential for studying ca
85 ssigned and reassigned cases fit this model, until now desulfurization of the synthetic gliotoxin ana
97 tudies of powerful accretion-disk winds have until now focused only on X-ray observations of local Se
98 ilene latifolia and papaya have been studied until now for the presence of evolutionary strata on the
99 avity, several approaches have been proposed until now for the quantum description of discrete geomet
100 achieved through functionalization have, up until now, found only systems where fluorescence is quen
102 e in the vicinity of the Bloch points, which until now has been accessible only through micromagnetic
103 ce, detailed understanding of the subject up until now has been lacking, especially toward tuning the
104 w on multicomponent protease inhibition that until now has mainly relied on blockage of the active si
105 working on complex optimization problems but until now has not been directly observed in nature as a
106 he proinflammatory IFN-gamma cytokine, which until now has only been detected transiently in acute in
108 xamples to demonstrate how GUMBOS chemistry, until now, has been beneficial to the general area of ma
109 clinical application of temozolomide, which, until now, has been largely limited to glioblastoma.
111 roperties of domain walls under illumination until now have been accessible only to macroscopic studi
114 step for the field of regenerative medicine; until now, histology and scanning electron microscopy ha
119 es have produced the most convincing results until now, including independent replication of the pred
122 he epicardium, a multipotent epithelium that until now is only established to normally generate cardi
123 t one factor that has not received attention until now is the possibility that study participants' re
124 the corresponding two-dimensional films, but until now it has been difficult, costly, and impractical
125 very early in the evolution of land plants, until now it has been unclear whether the established an
126 s-giant cores has successfully been modeled, until now it has not been possible to date their formati
142 ide effects of childhood cancer therapy, but until now little has been known about the relationship b
146 ypic diversity between individuals, however, until now, little molecular evidence has been provided.
154 probiotics in periodontal therapy; however, until now, most research has focused on lactobacilli pro
156 thetase-I mutations cause X-linked CMT6, but until now, mutations in the recessive forms of disease h
160 tion for anomalous radar data on Europa, but until now no penitentes have been identified conclusivel
163 of methane-metabolizing microorganisms, but, until now, no compelling evidence has existed for methan
171 le has remained an intriguing puzzle and, up until now, no molecular system has provided clear eviden
180 -cancer properties in vitro and in vivo; but until now, no study has focused on the role of SFN in HC
186 Artificial light-harvesting systems have until now not been able to self-assemble into structures
187 olutionary and epidemiological framework has until now not been available for influenza B viruses, de
192 ic stresses, namely salt and drought stress, until now only one transcription factor (TF) binding to
196 all termites known from the Cretaceous have, until now, only been winged reproductives (alates and de
199 gh molecular weight mixed disulfide adducts: until now, only Tg "adduct B" was identified as primaril
202 promoter motifs present in circadian genes, until now PIFs have not been shown to affect the circadi
205 titive nature of the Ae. tauschii genome has until now precluded the development of a reference-quali
211 n in 2-dimensional paper network assays, but until now, reagents have only been included as wet or dr
212 some eating disordered behaviors, which have until now received relatively little attention, have bee
213 its to miniaturization in insect brains have until now relied on information based on data collected
216 d the majority of wild flowering plants, but until now research on pesticide effects has been limited
226 nowledge of aspects that were not well known until now, such as GPCR complex stoichiometry and stabil
230 neurons with silver began in the 1800s, but until now the great resolving power of the laser scannin
231 stic role of SUMO proteases in model plants, until now the identity or the function of these regulato
236 inin (FHA), a surface-displayed adhesin, and until now, the consequences of this interaction were unk
239 -organic self-assembly approach in 2004/2005 until now, the direct synthesis of OMCs is still limited
249 viduals was reported more than 10 years ago, until now, the main function of this transcription facto
265 hyrolipomas seem to be a rare occurrence and until now their prevalence has only been reported in two
268 s are referred to as 'non-magnetic', because until now there has been no evidence that they have a ma
269 cological and evolutionary implications, but until now there has been no way of observing dynamic fai
274 king memory for subsequent manipulation, but until now, there has been no demonstration of this capac
275 e limitations of current analytical methods, until now, there has been no procedure capable of detect
278 g copper homeostasis within plant cells, but until now they have been studied mostly in model plant s
279 most of the polar organic solvents, and thus until now, they were not considered suitable for electro
287 ion "Did we make the right choice in waiting until now to ask your consent?" three of 60 (5%) respond
288 f the bleeding score (BS) have been proposed until now to confirm diagnosis but not to predict clinic
290 engineering and biomedical applications, but until now transformations have required external trigger
293 ue for non-medical (social) indications, but until now very few patients with cancer have achieved pr
296 ability of the adaptive immune system, which until now was thought to be mediated mainly by B cell an
300 ine release in the PFC has not been possible until now, when the validity of using the positron emiss
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