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1 s been unable to address their architectures until recently.
2 ial effects of ARNi have been little studied until recently.
3 and chemical nature have remained unresolved until recently.
4 tal structures were not reported for IgG4-Fc until recently.
5 alteration events have not been investigated until recently.
6 ited our ability to test this idea in humans until recently.
7 al contribution of microbes has been ignored until recently.
8 ion of metabolic resistance had been stalled until recently.
9 gional pain syndrome (CRPS) has been unclear until recently.
10 ation of its cellular dynamics in real time, until recently.
11 mammary epithelial cells was not recognized until recently.
12 sample sizes, which have not been available until recently.
13 NA triggers these responses remained unclear until recently.
14 ough the RCT pathway have not been available until recently.
15 The cause of PPCM has remained elusive until recently.
16 ed, it has not been tested in a natural host until recently.
17 ndicate that this increasing trend continued until recently.
18 abolic corrections, little progress was made until recently.
19 tibodies had not been found in sIBM patients until recently.
20 methyl group removal have remained elusive, until recently.
21 etals have not been experimentally evidenced until recently.
22 nsors that detect HIV-1 had remained elusive until recently.
23 dren with trisomy 18 and 13 has been limited until recently.
24 eractions--events that were hidden from view until recently.
25 s, screening TTN presented a major challenge until recently.
26 his dissimilar kinetics has remained elusive until recently.
27 on, the transduced progeny were not analyzed until recently.
28 latent or unnoticed as oilseed rape pathogen until recently.
29 se modifications regulate viral life cycles, until recently.
30 urons and related lineages, has been lacking until recently.
31 d SNARE complex disassembly remained unclear until recently.
32 egazettement (PADDD), a fact largely ignored until recently.
33 neuronal subtypes were not fully understood until recently.
34 has gone largely ignored in the genomics era until recently.
35 of which were unknown in ribosomal peptides until recently.
36 ic therapies, however, has been unsuccessful until recently.
40 f microbial species remain uncultivated and, until recently, about half of all known bacterial phyla
41 n well characterized, very little was known, until recently, about the role of DNA methylation and de
45 ingency management are largely unknown, and, until recently, an animal model of this human condition
46 (PBDEs), which were used as flame retardants until recently and are detected in the tissues of virtua
48 other glucose-lowering drugs) has been used, until recently, as a surrogate measure of their potentia
52 has been known since 1947 but poorly studied until recently because it was believed to only cause a m
53 ve fit of experimental data was not possible until recently, because of uncertainty regarding the den
54 ll molecule inhibitors of PARG activity have until recently been hampered by a lack of structural inf
55 nthesis of plant specialized metabolites has until recently been thought to be almost exclusively enc
56 , major primary producers in the ocean, have until recently been thought unimportant regarding partic
57 s disease where optic nerve involvement has, until recently, been a relatively overlooked feature.
58 ine-competent embryonic stem cell lines has, until recently, been limited to a small number of inbred
60 ishing territory for these populations, and, until recently, benthic sediment was thought to be the m
65 ility to realise this goal has been limited, until recently, by the need to develop synthetic strateg
75 HbF in the adult stage has remained limited until recently despite nearly 3 decades of molecular inv
77 w priority topic in the global health agenda until recently, despite its social and economic impact.
82 escents (age 10-14 years) has been neglected until recently, especially in low-income and middle-inco
85 ntly affects the outcome of transplantation, until recently, experiments using NHP models were perfor
86 display unique DNA-binding behavior, however until recently few examples which are both water-compati
87 ly one in six individuals on the planet and, until recently, few resources have been devoted to the t
89 e of this epigenetic mark was not understood until recently, following the discovery that the TET pro
90 delocalized over two neighboring atoms were until recently found only in gas-phase cations such as H
92 ) is claimed to be 40% to 60% inherited, but until recently genetic risk factors predisposing to CAD
94 ian H15 viruses is, however, quite rare and, until recently, geographically restricted to wild shoreb
95 n known in material science for decades, but until recently, halogen bonds in protein-ligand interact
97 involves intracellular [Ca(2+)] waves, which until recently have been associated with slow, global [C
98 level in structuring natural communities yet until recently have often overlooked the influence of in
99 s and model organisms like fish and mice but until recently have remained more opaque in humans and o
100 rgely unexplored because suitable detectors, until recently, have been either unavailable or cost pro
105 apies for peripheral vascular disease (PVD); until recently, however, it has not been possible to exa
116 the antibiotic sword remained unappreciated until recently, i.e., the cost that an antibiotic exerts
122 rting some aspect of each of these theories, until recently integrative evidence for the existence of
138 genesis during cold exposure in rodents, but until recently its presence in adult humans and its cont
139 nting is highly prevalent in the brain, yet, until recently, its central roles in neural processes ha
143 The rat is an important model organism that until recently lacked efficient genetic engineering tool
144 immune diseases and their pathogenesis, have until recently, largely been ignored and understudied.
145 nt difficulty culturing them, they remained, until recently, largely uncharacterized and mysterious.
148 very significant genetic component, however, until recently little was known of the underlying genes
149 itoylation), prenylation and GPI anchors but until recently little was truly known about their functi
161 ree relatives of patients with SCZ; however, until recently, molecular genetic approaches to test thi
167 have been developed and described; however, until recently much of this work had focused on patients
173 direct experimental data and by computation, until recently no examples of cationic gold carbenes/alp
177 characterization of such arrhythmia events, until recently, no precise tools existed to actively int
179 ch T-bet activates the Th1 gene profile, but until recently not much was known about the mechanisms t
199 pace necessary to answer this question have, until recently, remained beyond computational capabiliti
200 olipids, that have important activities but, until recently, remained undetected (or at least underst
201 the conserved nature of these elements has, until recently, rendered their expression profiling prob
203 mechanics of this process has never wavered, until recently researchers have been vexed by seemingly
214 romosomes remain poorly understood, because, until recently, techniques with sufficient resolution ha
216 CH4 ) sinks to upland soils and have assumed until recently that soils are the sole surface for CH4 e
218 ree-dimensional (3-D) spatial structure, but until recently the neural representation of space was st
219 5-Methylcytosine, which is found in DNA, was until recently the only nucleotide variant studied in te
224 known age must be used for calibration, and, until recently, the approach was untested for old stars
245 , are described to form an inflammasome, but until recently, the mechanism of inflammasome activation
250 been developed for dozens of organisms, but until recently, the pace of reconstruction has failed to
251 pite their potential to slow global warming, until recently, the radiative forcing associated with vo
259 e had a profound impact on neuroscience, but until recently their application has largely been confin
261 rise more than half of the human genome, but until recently their large-scale detection was time cons
263 Surgery is the mainstay of treatment and until recently there have been limited effective treatme
266 ars of study, there is no HIV-1 vaccine and, until recently, there was little hope for a protective i
269 ave a long history in antiviral therapy, but until recently, they have not been actively pursued for
270 otic genomes are pervasively transcribed but until recently this noncoding transcription was consider
276 ic glutamate receptors (mGluRs) were thought until recently to function mainly as stable homodimers,
277 t role in this process, it was not possible, until recently, to detail the timing of its recruitment
288 The most active RabGGTase inhibitor known until recently was an FTase inhibitor which hit RabGGTas
289 he existence of at least 126 species in what until recently was believed to be a single taxon: the ba
290 phenotype of paraneoplastic opsoclonus that until recently was likely considered idiopathic or posti
292 okinesis is a tightly regulated process that until recently was mostly viewed as a cell-autonomous ev
298 es are multisubunit chambered proteases and, until recently, were only known to participate in adenos
299 ever, this belief was not examined seriously until recently when the progress in both quantum gases a
300 much developed as an anti-infective approach until recently, when it was realized that the possible a
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