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1 s been unable to address their architectures until recently.
2 ial effects of ARNi have been little studied until recently.
3 and chemical nature have remained unresolved until recently.
4 tal structures were not reported for IgG4-Fc until recently.
5 alteration events have not been investigated until recently.
6 ited our ability to test this idea in humans until recently.
7 al contribution of microbes has been ignored until recently.
8 ion of metabolic resistance had been stalled until recently.
9 gional pain syndrome (CRPS) has been unclear until recently.
10 ation of its cellular dynamics in real time, until recently.
11  mammary epithelial cells was not recognized until recently.
12  sample sizes, which have not been available until recently.
13 NA triggers these responses remained unclear until recently.
14 ough the RCT pathway have not been available until recently.
15       The cause of PPCM has remained elusive until recently.
16 ed, it has not been tested in a natural host until recently.
17 ndicate that this increasing trend continued until recently.
18 abolic corrections, little progress was made until recently.
19 tibodies had not been found in sIBM patients until recently.
20  methyl group removal have remained elusive, until recently.
21 etals have not been experimentally evidenced until recently.
22 nsors that detect HIV-1 had remained elusive until recently.
23 dren with trisomy 18 and 13 has been limited until recently.
24 eractions--events that were hidden from view until recently.
25 s, screening TTN presented a major challenge until recently.
26 his dissimilar kinetics has remained elusive until recently.
27 on, the transduced progeny were not analyzed until recently.
28 latent or unnoticed as oilseed rape pathogen until recently.
29 se modifications regulate viral life cycles, until recently.
30 urons and related lineages, has been lacking until recently.
31 d SNARE complex disassembly remained unclear until recently.
32 egazettement (PADDD), a fact largely ignored until recently.
33  neuronal subtypes were not fully understood until recently.
34 has gone largely ignored in the genomics era until recently.
35  of which were unknown in ribosomal peptides until recently.
36 ic therapies, however, has been unsuccessful until recently.
37                                              Until recently, 20% to 30% of pediatric B-cell precursor
38                                              Until recently, 3-hydroxy-3-methylglutaryl-coenzyme A (H
39 nucleic acid interactions, however, remained until recently a great and unmet challenge.
40 f microbial species remain uncultivated and, until recently, about half of all known bacterial phyla
41 n well characterized, very little was known, until recently, about the role of DNA methylation and de
42                                              Until recently, all identified RNase P enzymes were a ri
43                                              Until recently, almost all the work done to study this l
44                                              Until recently, an animal model of this human condition
45 ingency management are largely unknown, and, until recently, an animal model of this human condition
46 (PBDEs), which were used as flame retardants until recently and are detected in the tissues of virtua
47                                              Until recently, apoptosis was the best known form of pro
48 other glucose-lowering drugs) has been used, until recently, as a surrogate measure of their potentia
49                                              Until recently, assessment of functional alterations und
50                                              Until recently, attention has focussed primarily on exha
51                                              Until recently, bacterial responses to changes in light
52 has been known since 1947 but poorly studied until recently because it was believed to only cause a m
53 ve fit of experimental data was not possible until recently, because of uncertainty regarding the den
54 ll molecule inhibitors of PARG activity have until recently been hampered by a lack of structural inf
55 nthesis of plant specialized metabolites has until recently been thought to be almost exclusively enc
56 , major primary producers in the ocean, have until recently been thought unimportant regarding partic
57 s disease where optic nerve involvement has, until recently, been a relatively overlooked feature.
58 ine-competent embryonic stem cell lines has, until recently, been limited to a small number of inbred
59           The presence of a PIKGT motif was, until recently, believed to allow discrimination of PabB
60 ishing territory for these populations, and, until recently, benthic sediment was thought to be the m
61                                         Yet, until recently, bilingualism was considered to be a comp
62                                              Until recently, BOS and other psychological disorders in
63                                              Until recently, BOS and other psychological disorders in
64 adio-frequency electronics has been limited, until recently, by the lack of suitable materials.
65 ility to realise this goal has been limited, until recently, by the need to develop synthetic strateg
66                                              Until recently cirrhosis was considered a single and ter
67  is critical for therapeutic approaches, but until recently could only be assessed at autopsy.
68 ad of hypervirulent GBS CC17, which were all until recently CPS type III.
69                                              Until recently cryo-EM structures were limited to approx
70 sed nanocrystals, synthetic challenges have, until recently, curbed progress.
71                                              Until recently, data from randomized controlled trials (
72                                  However, up until recently, data on the relationship between treatme
73                                              Until recently, deep-level phylogeny in Lepidoptera, the
74                                     However, until recently, deficiencies in our understanding of the
75  HbF in the adult stage has remained limited until recently despite nearly 3 decades of molecular inv
76                                              Until recently, despite achieving high potency against t
77 w priority topic in the global health agenda until recently, despite its social and economic impact.
78                                              Until recently, diagnostic fossil remains were found onl
79                                              Until recently, direct thermodynamically sound measureme
80                                              Until recently, enantioselective transition metal-cataly
81                                              Until recently, equivalent research in analogous ferroic
82 escents (age 10-14 years) has been neglected until recently, especially in low-income and middle-inco
83                                              Until recently, EV-D68 was considered to be an uncommon
84  result from a poorly lateralized brain, but until recently, evidence has been weak and indirect.
85 ntly affects the outcome of transplantation, until recently, experiments using NHP models were perfor
86 display unique DNA-binding behavior, however until recently few examples which are both water-compati
87 ly one in six individuals on the planet and, until recently, few resources have been devoted to the t
88                                              Until recently, few water utilities or researchers were
89 e of this epigenetic mark was not understood until recently, following the discovery that the TET pro
90  delocalized over two neighboring atoms were until recently found only in gas-phase cations such as H
91                                              Until recently gecko setae were assumed to be composed e
92 ) is claimed to be 40% to 60% inherited, but until recently genetic risk factors predisposing to CAD
93                                              Until recently, genome-wide, high-resolution experiments
94 ian H15 viruses is, however, quite rare and, until recently, geographically restricted to wild shoreb
95 n known in material science for decades, but until recently, halogen bonds in protein-ligand interact
96 gh latitudes of the summer hemisphere, which until recently has been the southern hemisphere.
97 involves intracellular [Ca(2+)] waves, which until recently have been associated with slow, global [C
98 level in structuring natural communities yet until recently have often overlooked the influence of in
99 s and model organisms like fish and mice but until recently have remained more opaque in humans and o
100 rgely unexplored because suitable detectors, until recently, have been either unavailable or cost pro
101                                              Until recently, hematopoietic stem cell transplantation
102                                              Until recently, however, assembled genome sequences of g
103                                              Until recently, however, constructing Z-olefins using th
104                                              Until recently, however, few in vivo studies had been ca
105 apies for peripheral vascular disease (PVD); until recently, however, it has not been possible to exa
106                                              Until recently, however, it was unclear how PCNA is remo
107                                              Until recently, however, little was known about the 'lan
108                                              Until recently, however, quantifying these contributions
109                              It has not been until recently, however, that targeting AXL has come und
110                                              Until recently, however, the direct ocean thermal contro
111                                              Until recently, however, the prevalence of resistant hyp
112                                              Until recently, however, the question, "Should we do thi
113                                              Until recently, human breast tissue and milk were presum
114                                              Until recently, human embryonic stem cells (hESCs) were
115                                              Until recently, hydrothermal vents were not considered t
116  the antibiotic sword remained unappreciated until recently, i.e., the cost that an antibiotic exerts
117                                              Until recently, immune responses in filovirus survivors
118                                              Until recently in Earth history, very large herbivores (
119                                              Until recently, in fact, inadequate methodologies and ex
120                                              Until recently, in vivo measurements were limited by the
121                                              Until recently, inclusive fitness has been widely accept
122 rting some aspect of each of these theories, until recently integrative evidence for the existence of
123  NO sensors that has been largely overlooked until recently, is described.
124                                              Until recently, it has been less clear whether, and to w
125                                              Until recently, it was assumed that OGT/OGA protein expr
126                                              Until recently, it was assumed that resolution of inflam
127                                              Until recently, it was believed that an unmodified oxyto
128                                          But until recently, it was believed to operate as a function
129                                              Until recently, it was difficult to differentiate betwee
130                                              Until recently, it was generally thought that cyanobacte
131                                              Until recently, it was mainly attributed to histamine re
132                                              Until recently, it was thought that degradation of the p
133                                              Until recently, it was thought that hydrogenase is not a
134                                              Until recently, it was thought that internalization of t
135                                              Until recently, it was thought that these regulatory net
136                                              Until recently, it was unclear how these cytotoxins targ
137                                              Until recently, it was unclear whether this magnetizatio
138 genesis during cold exposure in rodents, but until recently its presence in adult humans and its cont
139 nting is highly prevalent in the brain, yet, until recently, its central roles in neural processes ha
140                                              Until recently, its reliability was explained by the ass
141                                              Until recently, knowledge about droplets in the nervous
142                                              Until recently, knowledge of cancer pain mechanisms was
143  The rat is an important model organism that until recently lacked efficient genetic engineering tool
144 immune diseases and their pathogenesis, have until recently, largely been ignored and understudied.
145 nt difficulty culturing them, they remained, until recently, largely uncharacterized and mysterious.
146                                      Purpose Until recently, limited options existed for patients wit
147                                     However, until recently, limited tools offered the ability to pre
148 very significant genetic component, however, until recently little was known of the underlying genes
149 itoylation), prenylation and GPI anchors but until recently little was truly known about their functi
150                                              Until recently, little attention has been paid to how pu
151                                              Until recently, little has been known about the nature o
152                                              Until recently, little was known about MAIT cells; howev
153                                              Until recently, little was known about the molecular cha
154                                              Until recently, living radical polymerizations could not
155                                              Until recently, MA experiments were limited by the cost
156          Few methylation variants were known until recently, making it possible to begin to address m
157                                              Until recently many studies of bone remodeling at the ce
158                                              Until recently, memory T cell populations were considere
159                                              Until recently, metabolic engineering in plants relied o
160                                              Until recently, microRNAs (miRNAs) were considered to be
161 ree relatives of patients with SCZ; however, until recently, molecular genetic approaches to test thi
162                                              Until recently most of the models of the immune system t
163                                              Until recently, most [(18)F]-radiotracers were generated
164                                              Until recently, most clinicians and scientists believed
165                               Since 1927 and until recently, most models describing the spread of dis
166                                              Until recently, most studies examining GBV have been con
167  have been developed and described; however, until recently much of this work had focused on patients
168                                              Until recently, naturally occurring amyloid beta-protein
169                                     However, until recently, NMR methodology was limited by the time
170                                              Until recently, NMR spectroscopy has yielded structures
171                                              Until recently no behavioural function had been found fo
172                                 Nevertheless until recently no direct demonstration of the causal rel
173 direct experimental data and by computation, until recently no examples of cationic gold carbenes/alp
174                                     However, until recently no gas-phase Criegee intermediate had bee
175                                              Until recently, no ideal valid, feasible, and reliable s
176                                              Until recently, no interventional study in patients with
177  characterization of such arrhythmia events, until recently, no precise tools existed to actively int
178                                              Until recently, no recurrent translocations were identif
179 ch T-bet activates the Th1 gene profile, but until recently not much was known about the mechanisms t
180                                              Until recently, not many such antibodies were known, but
181                                     However, until recently, not much has been known regarding the sp
182 xist, yet such complex constructions seemed, until recently, not to be present in nature.
183                      Because of the absence, until recently of reliable animal models of allograft ac
184                                              Until recently only Ca(2+) was considered to serve as a
185                                              Until recently, only a single naturally occurring stereo
186                                              Until recently, our laboratory relied on conventional PC
187                                              Until recently, our understanding of antibody recognitio
188 the living human brain has not been possible until recently owing to a lack of suitable tools.
189                                              Until recently, possible treatment options were iris pri
190                                              Until recently, production facilities relied on the use
191                                              Until recently, programmed cell death was conceived of a
192                                              Until recently, psoriasis was treated by agents or appro
193                                              Until recently, radiation therapy (RT) was believed to m
194 egulator of vital importance to insects, was until recently regarded as a mystery.
195                                              Until recently, relatively few SNPs were known in the ze
196                                              Until recently, relatively little has been known about t
197 f the "chemistry" present in the kernel was, until recently, relatively unexplored.
198 (HRS) in a disease whose pathophysiology has until recently remained a mystery.
199 pace necessary to answer this question have, until recently, remained beyond computational capabiliti
200 olipids, that have important activities but, until recently, remained undetected (or at least underst
201  the conserved nature of these elements has, until recently, rendered their expression profiling prob
202                                              Until recently, research has focused almost entirely on
203 mechanics of this process has never wavered, until recently researchers have been vexed by seemingly
204 nsistently been reported in CMN samples, but until recently results have been contradictory.
205                                              Until recently, Rsk activation was thought to be exclusi
206                                              Until recently, significant advances in our understandin
207                                              Until recently studies of microbial vent communities hav
208                                           Up until recently, studies largely focused on identifying c
209                                              Until recently such studies were performed using classic
210                                              Until recently, such cases were termed suspicious for CA
211                                              Until recently, T-box transcription factors were thought
212                                              Until recently, technical limitations curtailed our abil
213                                              Until recently, technical limitations have prevented qua
214 romosomes remain poorly understood, because, until recently, techniques with sufficient resolution ha
215                                              Until recently, technological limitations have made it d
216 CH4 ) sinks to upland soils and have assumed until recently that soils are the sole surface for CH4 e
217                Nevertheless, it has not been until recently that the gut and its attendant components
218 ree-dimensional (3-D) spatial structure, but until recently the neural representation of space was st
219 5-Methylcytosine, which is found in DNA, was until recently the only nucleotide variant studied in te
220                                     However, until recently the public health implications of mass in
221                                              Until recently the rapid divergence of cnn made identifi
222                                              Until recently the set of "model" species used commonly
223                                     However, until recently the utility of these tags was questionabl
224 known age must be used for calibration, and, until recently, the approach was untested for old stars
225                                              Until recently, the approved treatment regimens for pati
226                                              Until recently, the basic leucine zipper transcription f
227                                              Until recently, the cause of the majority of CHD was unk
228                                              Until recently, the CNS was considered to be devoid of a
229                                              Until recently, the contribution of the PC layer to neut
230                                              Until recently, the dearth of techniques for cell type i
231                                              Until recently, the developmental processes that led to
232                                              Until recently, the disease was associated with two subs
233                                              Until recently, the dual roles of mitochondria in ATP pr
234                                              Until recently, the evidence base for these devices had
235                                              Until recently, the evidence supporting the importance o
236                                              Until recently, the freeze-drying process and formulatio
237                                              Until recently, the fundamental mechanisms of temperatur
238                                              Until recently, the heterogeneity of the constituent neu
239                                              Until recently, the high sequence conservation between h
240                                     However, until recently, the identification of causal mutations t
241                                              Until recently, the known host range of hepadnaviruses w
242                                              Until recently, the known roles of lymphatic endothelial
243                                     However, until recently, the lack of HTS-compatible assay technol
244                                              Until recently, the majority of such studies focused on
245 , are described to form an inflammasome, but until recently, the mechanism of inflammasome activation
246                                              Until recently, the mechanisms underlying these effects
247                                              Until recently, the only mathematical model for long-ter
248                                              Until recently, the only strategy to develop drugs regul
249                                              Until recently, the origin of the HIV-1 group M pandemic
250  been developed for dozens of organisms, but until recently, the pace of reconstruction has failed to
251 pite their potential to slow global warming, until recently, the radiative forcing associated with vo
252                                              Until recently, the result of this work has been the ide
253                                              Until recently, the sole model of iNKT deficiency target
254                                              Until recently, the standard of care for branch RVO-asso
255                                              Until recently, the study of microbial diversity has mai
256                                              Until recently, the study of plasticity of neural circui
257                                              Until recently, the study of these two populations has b
258                                              Until recently, the vast majority of cross-coupling proc
259 e had a profound impact on neuroscience, but until recently their application has largely been confin
260 finery for lignocellulose deconstruction but until recently their costs were regarded as high.
261 rise more than half of the human genome, but until recently their large-scale detection was time cons
262                                              Until recently there has been little interest in the ide
263     Surgery is the mainstay of treatment and until recently there have been limited effective treatme
264                                              Until recently, there did not exist a direct way to make
265                                     However, until recently, there has been little direct information
266 ars of study, there is no HIV-1 vaccine and, until recently, there was little hope for a protective i
267                                              Until recently, there were few options if cardiogenic sh
268                                              Until recently, there were limited options for patients
269 ave a long history in antiviral therapy, but until recently, they have not been actively pursued for
270 otic genomes are pervasively transcribed but until recently this noncoding transcription was consider
271                                              Until recently this restriction was believed to be not i
272                                              Until recently, this decline has been largely attributed
273                                              Until recently, this entity was often misdiagnosed, ther
274                                              Until recently, this technique has been applied to many
275                                              Until recently, this was thought to be unidirectional, p
276 ic glutamate receptors (mGluRs) were thought until recently to function mainly as stable homodimers,
277 t role in this process, it was not possible, until recently, to detail the timing of its recruitment
278                                              Until recently, transcriptome analyses of single cells h
279                                              Until recently, treatment required surgical reconstructi
280                                              Until recently, turn taking was thought to be unique to
281                                              Until recently, U(IV) was assumed to exist predominantly
282                                              Until recently, Uganda's crater lakes were considered sc
283                                              Until recently, use of photoemission electron microscopy
284                                              Until recently, very few algorithms considered the dynam
285                                              Until recently, Vidian neurectomy had been applied mainl
286                     In contrast to human IQ, until recently, views of learning and cognition in anima
287                                              Until recently, vitamin K antagonists were the only avai
288    The most active RabGGTase inhibitor known until recently was an FTase inhibitor which hit RabGGTas
289 he existence of at least 126 species in what until recently was believed to be a single taxon: the ba
290  phenotype of paraneoplastic opsoclonus that until recently was likely considered idiopathic or posti
291 tre for HEV, 9 were due to genotype 4, which until recently was limited to Asia.
292 okinesis is a tightly regulated process that until recently was mostly viewed as a cell-autonomous ev
293           The metabolic fate of anthocyanins until recently was relatively unknown, primarily as a re
294 GE]) is crucial for glucose homeostasis and, until recently, was thought to be invariable.
295                                              Until recently, waste management for national immunizati
296 g for insights into the disease process that until recently were not possible.
297                 Notably missing among these, until recently, were applications that required good cha
298 es are multisubunit chambered proteases and, until recently, were only known to participate in adenos
299 ever, this belief was not examined seriously until recently when the progress in both quantum gases a
300 much developed as an anti-infective approach until recently, when it was realized that the possible a

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