ライフサイエンスコーパス: untransformed

1 with lower bone mineral density, whereas an untransformed 25(OH)D concentration <20 ng/mL was not.

2 Oncogenic activation of KRAS in normal, untransformed acinar cells in the pancreatic tissues of

3 Detachment of most untransformed adherent cells from the extracellular matr

4 sing a simplified version of the model, with untransformed AFP values, a cut-off value of 2 was ident

5 to regulate ERK and Smad signaling in human untransformed and cancer cell lines, we showed that the

6 ate the method, we compare the filtration of untransformed and HRas(V12)-transformed murine ovary cel

7 t per capita participation variables in both untransformed and in difference models, further corrobor

8 cs to whole blood total mercury levels (TBM; untransformed and log-transformed) based on R2 values.

9 n of KIF2C and, to a lesser extent, KIF2A in untransformed and mutant K-Ras-transformed cells is regu

10 ncrease RhoA-guanosine triphosphate (GTP) in untransformed and transformed cell lines and determine t

11 The differential sensitivities of untransformed and transformed cells to induction of apop

12 of two cancer-related genes in a variety of untransformed and transformed human cell lines.

13 R-21 negatively altered TGFBR2 expression in untransformed and transformed human prostate epithelial

14 ling further potentiates this effect in both untransformed and transformed human prostate epithelial

15 nce but with much reduced expression, remain untransformed, and grow continuously.

16 RCA1 and a slight improvement compared with untransformed Arabidopsis plants.

17 inactivation of p53 is insufficient to allow untransformed B cells and B-cell lymphomas to survive wi

18 microM in each case, but it had no effect on untransformed Ba/F3 cells growing in IL-3 or on Ba/F3 ce

19 leen resulted in a transient accumulation of untransformed Ba/F3 cells, but not Ba/F3.

20 tus in wrestlers, but it is advisable to use untransformed BIA measurements rather than to convert re

21 For example, nuclear extracts from two human untransformed breast epithelial cell lines expressed onl

22 In contrast, untransformed breast epithelial cells arrest in G1, rema

23 In transient transfection analysis in untransformed breast epithelial cells, c-Rel-p52 or -p50

24 of Hsp72 in certain cancer cells, but not in untransformed breast epithelial cells, triggers senescen

25 duction increased markedly in anti-sense and untransformed, but not overexpressor, roots with KCN tre

26 labile fraction, py-OM added to SOM largely untransformed by soil microbes.

27 ere visually green in color when compared to untransformed carrot cells, and this offered a visual se

28 es to spread can be investigated in primary, untransformed CD4(+) cells.

29 Untransformed CD4(+) Th1 cells stimulated with Ag and AP

30 nduced by serum deprivation or confluency in untransformed CEF.

31 We therefore tested primary untransformed cell cultures that lack CCR5 and CXCR4, in

32 absent or substantially reduced compared to untransformed cell lines or leukemia cells lacking BCR/A

33 Untransformed cell lines were resistant to both ERBB4 an

34 Transfection of both E1A-transformed and untransformed cell lines with a series of mutant promote

35 high activities of src kinases as well as in untransformed cell lines.

36 er cells but not in the membranes of several untransformed cell lines.

37 n nine immortal human cell lines than in six untransformed cell strains.

38 This interaction enables an untransformed cell to respond to stress-induced, p53-dep

39 rence by vFosAP-1 compared with AP-1 from an untransformed cell.

40 tates from BCR/ABL-transformed, but not from untransformed, cell lines contained PI3K lipid kinase ac

41 is dispensable for FA pathway activation in untransformed cells and the Rad18 and FA pathways are se

42 In addition, untransformed cells appear to possess one or more active

43 y in all three transformed lines compared to untransformed cells by VP16 treatment, while slight acti

44 atmospheric oxygen levels, proliferation of untransformed cells continues for extended periods of ti

45 tinuously exposed to microtubule inhibitors, untransformed cells eventually slip out of mitosis after

46 the apoptotic response that is triggered in untransformed cells following inappropriate cell-cycling

47 ht of beta-Ala betaine and Gly betaine) than untransformed cells grown in liquid medium containing 10

48 cultures, but genetic manipulation of these untransformed cells has been technically challenging.

49 ession imparted malignant characteristics to untransformed cells if p53 was compromised, promoting an

50 lular matrix substrate arrests the growth of untransformed cells in the G1 phase.

51 er, suppression of this apoptotic pathway in untransformed cells is not mediated only by adhesion to

52 Ectopic CK2 expression in untransformed cells led to increased IKK-i/IKKepsilon mR

53 Inhibition of RNAP II in untransformed cells like Rat-1 or human AG1522 fibroblas

54 Untransformed cells or those containing the parent const

55 Importantly, upon Ras expression, untransformed cells started responding to knockdown of H

56 ow rate of expression and activity levels in untransformed cells such as MCF10A.

57 ch hydrogen peroxide (H(2)O(2)) was added to untransformed cells to mimic the increase in ROS induced

58 Whereas untransformed cells were sensitive to apoptotic death in

59 Also, while untransformed cells were sessile for long periods, BCR/A

60 Further, stimulation of untransformed cells with H(2)O(2) or pervanadate increas

61 Pretreatment of untransformed cells with low doses of arsenic induced co

62 In untransformed cells with normal p53, the preferred mode

63 regulation of ODC in RIE-1 cells, comparing untransformed cells with those transformed by an activat

64 totoxic effects on tumor cells while sparing untransformed cells, and Bcl-x(L) is reported to efficie

65 transcriptionally upregulated these miRNA in untransformed cells, indicating that this Myc-induced mi

66 Unlike untransformed cells, most cancer cells demonstrate reduc

67 BRG1 could not initiate tumor development in untransformed cells, our results indicate that transform

68 eta was phosphorylated at Ser 226/Ser 255 in untransformed cells, phosphorylation was absent in leuke

69 ur previous work has shown that, in cultured untransformed cells, preventing elimination of oxidized

70 transformed breast epithelial cells than in untransformed cells, suggesting a degree of tumor select

71 h inhibitor selectively in cancer but not in untransformed cells.

72 itive to many signals that inhibit growth of untransformed cells.

73 eported NT ES cells derived from transfer of untransformed cells.

74 group of approximately 25 mRNAs compared to untransformed cells.

75 romotes and sustains cell-matrix adhesion of untransformed cells.

76 xygen species (ROS) compared with quiescent, untransformed cells.

77 protease phenotypes in both transformed and untransformed cells.

78 of inducing apoptosis of transformed but not untransformed cells.

79 was approximately 10-fold below the level of untransformed cells.

80 tivates caspases when added to extracts from untransformed cells.

81 are normally observed only during S-phase in untransformed cells.

82 and 8-fold less, respectively, than those in untransformed cells.

83 eta interacted weakly with the apoptosome in untransformed cells.

84 formed cell lines have longer telomeres than untransformed chicken lymphoid cells and have high level

85 O cells expressing human CAR, in contrast to untransformed CHO cells, all specifically bound the sCAR

86 increase in genomic complexity compared with untransformed CLL, but it presented clear differences in

87 es were significantly lower than those of an untransformed colonic epithelial cell line.

88 malate, succinate, and acetate compared with untransformed control alfalfa plants.

89 Compared with untransformed control cells, malignant transformants car

90 n that observed following ATR suppression in untransformed control cells.

91 BRI1-silenced cells as compared to levels in untransformed control cells.

92 nd 23.1 and 35.2 mug per aphid for BGL-1 and untransformed control exudates, respectively, confirm th

93 cumulation of TGA5 transcripts compared with untransformed control plants, while the TGA5-sense lines

94 her salt tolerance as compared to equivalent untransformed control plants.

95 inase inhibitor that was not detected in the untransformed control plants.

96 erived from c-myc : Cf-9 tobacco compared to untransformed control.

97 btained from BnCysP1 male-sterile plants and untransformed controls showed 1:1 (tolerant:sensitive) r

98 We found that in GSCs, but not untransformed controls, PHF5A facilitates recognition of

99 d vitamin C levels were compared to those in untransformed controls.

100 nsformed plants were more resistant than the untransformed controls.

101 in an oxalic acid solution when compared to untransformed controls.

102 3.2 kb mRNA species that was not present in untransformed controls.

103 0-fold increase in the H/G ratio relative to untransformed controls.

104 The t-test on untransformed costs ignores the skewness in cost data, t

105 on untransformed costs, the Wilcoxon test on untransformed costs, and the Student t-test on log-trans

106 ds were commonly used: the Student t-test on untransformed costs, the Wilcoxon test on untransformed

107 In articles that used t-tests on untransformed costs, two statistically significant resul

108 total of 23 Wilcoxon tests and 24 t-tests on untransformed costs.

109 ts the same fatal outcomes in animals as its untransformed counterpart and, importantly, maintains th

110 of extracellular matrix (ECM) synthesized by untransformed, cultured human corneal fibroblasts in lon

111 dicate that conventional kinetic analysis of untransformed data is less sensitive to mean zero noise

112 Compared with compartmental analysis of untransformed data, the graphic method enables derivatio

113 For the available raw, untransformed data, the mean ratio of CL and CPS was 10.

114 rove valuable for the generation of primary, untransformed DCs in which candidate genes have been ove

115 port the derivation of long-term cultures of untransformed DCs, uniformly expressing a defined mutant

116 lls and was not prevented by the presence of untransformed DCs.

117 difficult to study on a genome-wide level in untransformed differentiated metazoan cells.

118 hrough the use of high-throughput screens in untransformed diploid epithelial cells.

119 omes were particularly good in patients with untransformed disease and related donors, whereas patien

120 Whereas untransformed early passage fibroblasts undergo cell cyc

121 d chromosome instability in tumor cells, how untransformed ECs respond to excess centrosomes is poorl

122 d death domain protein (FADD) in a number of untransformed epithelial cell lines.

123 esion markedly reduces the migfilin level in untransformed epithelial cells and concomitantly induces

124 nducible resistance to ionizing radiation in untransformed epithelial cells pre-exposed to low-dose i

125 Depletion of CAF1 in untransformed epithelial cells using siRNA was sufficien

126 rictive link between anchorage and growth in untransformed epithelial cells was observed and disrupte

127 d to be more active in KLF5 degradation than untransformed epithelial cells, yet their proteasome act

128 beta-mediated up-regulation of these CKIs in untransformed epithelial cells.

129 acellular signal-regulated kinase (ERK) 1 in untransformed epithelial cells.

130 Using untransformed ex situ human intestinal enteroids and tra

131 ith PIR2 compared to seedlings infected with untransformed F. oxysporum or that transformed with vect

132 transmitted via pollen when out-crossed with untransformed female plants.

133 letion of the Cdt1 inhibitor, geminin, in an untransformed fibroblast cell line is undetectable by st

134 compared genetically related transformed and untransformed fibroblast cells in vitro for proliferatio

135 e, transient stimulation of ERK signaling in untransformed fibroblasts by adhesion on fibronectin or

136 a comparison of the HeLa cancer cell line to untransformed fibroblasts suggests that HeLa cells produ

137 PML also regulates MHC expression in untransformed fibroblasts.

138 ad histology consistent with HT, and 154 had untransformed FL (median time to recurrence, 9.6 v 22.8

139 fferences in the basal metabolic activity of untransformed from malignant breast cells (P < 0.05) and

140 -vine ripening and prolonged shelf life over untransformed fruits.

141 roid binding activity of the immunopurified, untransformed GR.hsp90 complex in a manner that is preve

142 ents was 37 months versus 163 months for the untransformed group (P = .0029).

143 nstrated by chromatin immunoprecipitation in untransformed hepatocytes, but was markedly reduced in p

144 to these genes as "Suz12 repressed" genes in untransformed hepatocytes.

145 o interact with a 56-kDa cellular protein in untransformed, herpesvirus saimiri-transformed, and Jurk

146 mammary epithelial (HME) and Ras transfected untransformed HME (MCF-10A1 neo N) cells were less susce

147 CDC14A phosphatase activity (hCDC14A(PD)) in untransformed hTERT-RPE1 and colorectal cancer (HCT116)

148 -type (WT) or mutant IDH1 into immortalized, untransformed human astrocytes, then monitored transform

149 30% cytochalasin-induced cleavage failure in untransformed human cell cultures did not establish cent

150 We show that in untransformed human cells, timing of replication is high

151 in amounts at least 200-fold greater than in untransformed human cells.

152 Stable depletion of PTEN in untransformed human fibroblasts and epithelial cells als

153 NA) synthesis led to premature senescence of untransformed human fibroblasts, whose features include

154 mal escape from X chromosome inactivation in untransformed human fibroblasts.

155 type III receptor (RIII) when compared with untransformed human mammary epithelial cells.

156 Upon expression of HER2, untransformed human mammary epithelial MCF-10A cells und

157 ased actin dynamics in the immune synapse of untransformed human T cells under reducing conditions.

158 ate was also detected at Ser(380) in PTEN in untransformed human T cells.

159 otein levels sensitizes transformed, but not untransformed, human cells to therapeutic doses of the a

160 as also applied to comparable regions on the untransformed image datasets.

161 carcinoma cell lines tested as compared with untransformed immortal mammary epithelial cell lines, su

162 Meanwhile, HBZ is expressed in both untransformed infected cells and ATLL cells and is invol

163 ously demonstrated that growth inhibition of untransformed intestinal epithelial cells by transformin

164 Here, we addressed the role of p27 in untransformed intestinal epithelial cells in vivo and th

165 RP-8/14 complex was detected only in primary untransformed keratinocytes and not in the HPV-infected

166 hed in transgenic mosquitoes relative to the untransformed laboratory strain.

167 Genomic analysis of untransformed Landsberg erecta plants demonstrated that

168 Untransformed last-sighting date frequency distributions

169 ls of damage greater than those observed for untransformed leaves.

170 larval weights as compared to larvae fed on untransformed leaves.

171 eta(3) induction of TGFbeta(1) expression in untransformed lung and intestinal epithelial cells.

172 were found to contain higher PIC levels than untransformed lung epithelial cells.

173 decrease in IRGM expression (P < 10(-12)) in untransformed lymphocytes from CD patients.

174 f centrosomal proteins leads to G1 arrest in untransformed mammalian cells has been a mystery.

175 Therefore, previously untransformed mammary cells may establish residence in t

176 his p53 modification and its consequences in untransformed mammary epithelial cells and tissues.

177 we show that when detached from the matrix, untransformed mammary epithelial cells undergo metabolic

178 ctopic coexpression of c-Rel and CK2alpha in untransformed mammary epithelial cells was sufficient to

179 IKKalpha induced p52, RelB, and cyclin D1 in untransformed mammary epithelial cells.

180 M-2 with a membrane-localization signal into untransformed MCF-10-2A cells not susceptible to PNC-27

181 n 7 of 9 breast tumor lines when compared to untransformed MCF-10A cells.

182 IKKepsilon and kinase activity compared with untransformed MCF-10F breast epithelial cells.

183 of IKKalpha, IKKbeta, and CK2 activity than untransformed MCF-10F mammary epithelial cells.

184 High levels of RANK in untransformed MCF10A cells induce changes associated wit

185 Stable overexpression of Bcl-2 in the untransformed MCF10A cells was able to recapitulate the

186 Expression of Her2 in untransformed MCF10A mammary epithelial cells caused tra

187 we found that ATF3 enhances apoptosis in the untransformed MCF10A mammary epithelial cells, but prote

188 -carcinogenic cell fates by interaction with untransformed MECs during regenerative growth.

189 melanoma cells and certain albino mutants in untransformed melanocytes are targeted to proteolytic de

190 2 cells containing these mutants have a flat untransformed morphological phenotype and do not express

191 agen in alpha mouse liver 12 hepatocytes (an untransformed mouse cell line) that had undergone EMT af

192 While nontoxic to untransformed mouse cells, FTI triggers a massive RhoB-d

193 In transformed and untransformed mouse fibroblasts, the most prominent cell

194 We report that untransformed mouse mammary cells that have been enginee

195 ng nuclear extracts from E1A-transformed and untransformed murine keratinocytes using radiolabeled po

196 >500-fold more resistant to hygromycin than untransformed mycelia.

197 ecovered from mice immunized in vivo with an untransformed myoblastoid cell line.

198 t also by independent sarcoma cell lines and untransformed myoblastoid cell lines.

199 By two weeks postinoculation with TBSV, all untransformed N. benthamiana plants and transformed nega

200 required for GSC expansion, as compared with untransformed neural stem cells (NSCs) and fibroblasts.

201 creased in ras-transformed cells relative to untransformed NIH 3T3 cells and only slightly reduced as

202 ese protease phenotypes can be duplicated in untransformed NIH 3T3 cells that express platelet-derive

203 n K-ras-transformed NIH 3T3 cells but not in untransformed NIH 3T3 cells.

204 In untransformed NIH3T3 cells, retroviral-mediated transduc

205 at normally are down-regulated in quiescent, untransformed NIH3T3 cells.

206 Here, TGF-beta1 treatment of untransformed NMuMG mammary epithelial and MDA-MB-231 br

207 ely with transformed KNRK cells and not with untransformed NRK cells.

208 d spread out) morphology resembling those of untransformed NRK cells.

209 PHF5A knockdown in GSCs, but not untransformed NSCs, astrocytes, or fibroblasts, inhibite

210 Through dye-labeling experiments in untransformed onion epidermal and tobacco culture cells

211 rend in the risk of incident hypertension by untransformed or log-transformed continuous values of 25

212 tially in transformed cell lines, but not in untransformed or primary cells.

213 he TNF receptor family, induced apoptosis in untransformed or tumor-derived cells and the apoptotic f

214 ormally, suggesting that the morphologically untransformed parasites are biochemically mature ookinet

215 e parent, since use of a CHS mutant, tt4, as untransformed parent resulted in uniform green F1 plants

216 cells transformed by Bcr/Abl, but not in the untransformed parental cell lines in the absence of IL-3

217 Fas cell surface expression as compared with untransformed parental cell lines.

218 s not changed significantly from that of the untransformed parental cells, but the saturation density

219 bacterial communities was largely similar to untransformed plant roots with approximately 74% of the

220 ercury at approximately 10 times the rate of untransformed plantlets.

221 Membranes of untransformed plants and calli or those transformed with

222 ls are 2-fold higher in BGL-1 leaves than in untransformed plants but do not increase in other organs

223 In untransformed plants of the Landsberg ecotype, which con

224 Analyses of callus and untransformed plants regenerated from callus indicated t

225 Reciprocal backcrosses to untransformed plants showed unequal transmission of the

226 Treatment of untransformed plants with an apyrase inhibitor increased

227 hoots (up to 400 mug Cu. g(-1)), compared to untransformed plants, over the limits established for Cu

228 were morphologically indistinguishable from untransformed plants, when CTB was constitutively expres

229 four- to fivefold greater than extracts from untransformed plants, whereas no difference was observed

230 e fertile, flowered and set seeds similar to untransformed plants.

231 photosynthetic rates comparable to those of untransformed plants.

232 mature tobacco leaves of vector control and untransformed plants.

233 ass and removed more TNT from the media than untransformed plants.

234 ettuce expressing prM/E proteins, but not in untransformed plants.

235 ht (1.5-fold), and leaf area (1.6-fold) than untransformed plants.

236 by systematic batch effects (over 98% of all untransformed probes were significantly different by ANO

237 SSeCKS/Gravin protein was detected in untransformed rat and human prostate epithelial cell lin

238 In untransformed, resting cells, the ARE targets GM-CSF mRN

239 Untransformed results are potentially useful in evaluati

240 Incubation of untransformed RIE-1 cells in the presence of conditioned

241 While untransformed RLEs undergo growth arrest and apoptosis i

242 of Dkk-3 enhanced cell cycle progression in untransformed RWPE-1 prostate epithelial cells.

243 inaric acids, neither of which is present in untransformed soybean embryos.

244 ced up to 10 times more volatile Se than the untransformed strain when both were supplied with Se-Met

245 Furthermore, treatment of untransformed sunflower leaves with jasmonic acid, salic

246 on in leukemic T lymphocytes than in normal, untransformed T lymphoblasts.

247 Notch1 expression was higher in untransformed thymocytes in the absence of ZFP36L1 and Z

248 arman correlation analyses were performed on untransformed time series and on transformed percentage

249 g ras at this moderately enhanced level were untransformed, transformation must follow either a nondo

250 sformed cells express a proneural signature, untransformed tumor-associated cells, including reactive

251 core (SL1), and the second, on the original, untransformed variables (SL2).

252 However, in untransformed WI-38 fibroblasts, RECQL4 was found to be

253 st, the chl1::Tag1 mutant was backcrossed to untransformed wild-type Arabidopsis plants to remove the