ライフサイエンスコーパス: untreated

1 Alcohol dependence is often untreated.

2 angiography showed severe CAD that was left untreated.

3 isorder that can be life-threatening if left untreated.

4 an lead to strokes and heart attacks if left untreated.

5 in hypertension that is potentially fatal if untreated.

6 of atrial fibrillation patients still remain untreated.

7 artially treated), and a third plot was left untreated.

8 ly half of DCIS may progress to IDC, if left untreated.

9 h hyperparathyroidism remain undiagnosed and untreated.

10 ged but potentially fatal in severe cases if untreated.

11 untreated (TAVR+PCI: 10.4%; severe CAD left untreated: 15.4%; no-CAD: 14.8%; P=0.765).

12 uminal B 10-year metastasis: treated, 37% vs untreated, 21%; P = .006 for interaction).

13 ased in AAV-TrkB-treated (9/9) compared with untreated (3/5) or AAV-GFP-treated (4/10; P < 0.027) ani

14 uminal B 10-year metastasis: treated, 33% vs untreated, 55%; nonluminal B 10-year metastasis: treated

15 7800 +/- 1500 kmol DSi year(-1)) compared to untreated (69500 kmol DSi year(-1)) indicate that the pr

16 Untreated (8/14) and previously treated (6/14) eyes show

17 astine, and dacarbazine (ABVD) in previously untreated-according to European Organisation for Researc

18 2%) of infections remaining asymptomatic and untreated, accounting for 89% (95% CrI 82%-93%) of onwar

19 Conversely, untreated/adjacent teeth displayed GRD increase at T3 (P

20 eth submitted to FGGs were compared with 247 untreated/adjacent teeth.

21 mised placebo-controlled trial in previously untreated adult patients (aged >/=18 years) diagnosed wi

22 ns in skin biopsy samples of EM lesions from untreated adult patients with Lyme disease in comparison

23 Participants were previously untreated adults (HIV-1 RNA >/=500 copies per mL) with e

24 virological suppression in 92% of previously untreated adults and was non-inferior to coformulated do

25 es chlamydial infection in both children and untreated adults, suggesting a form of herd protection.

26 or to the dolutegravir regimen in previously untreated adults.

27 milar candidate for patients with previously untreated advanced follicular lymphoma.

28 (IPI) in patients with previously treated or untreated advanced melanoma led to subsequent clinical d

29 , in a 1:1:1 ratio, patients with previously untreated advanced melanoma to receive nivolumab at a do

30 a (November 2005-March 2012) with previously untreated advanced or metastatic colorectal cancer whose

31 Among patients with KRAS wt untreated advanced or metastatic colorectal cancer, ther

32 lts (aged 18 years or older) with previously untreated, advanced stage (Ann Arbor stage III or IV) fo

33 who were treated with methotrexate and eight untreated age-matched control subjects by using Wilcoxon

34 luded that the benefits are moderate because untreated amblyopia results in permanent, uncorrectable

35 5 and AML17 trials, patients with previously untreated AML and confirmed FLT3-activating mutations, m

36 ), and fewer mitochondria than controls from untreated AML animals.

37 The efficacy of ceritinib in patients with untreated anaplastic lymphoma kinase (ALK)-rearranged no

38 , we observed severe infiltration on POD7 in untreated and 1-mg TAC recipients compared with minor hi

39 d by enzyme replacement therapy (ERT) and 54 untreated and 19 ERT-treated Fabry females, along with 3

40 Urine samples were studied from 34 untreated and 33 Fabry males treated by enzyme replaceme

41 od (particularly T lymphocytes) derived from untreated and 4-6 and 18-26 mo Tecfidera-treated stable

42 Moreover, we monitored their frequencies in untreated and fingolimod- or natalizumab-treated patient

43 x vivo, in contrast to eosinophils from both untreated and fungal allergen-challenged IL5tg mice, whi

44 een blood plasma samples acquired from NPC1 (untreated and miglustat treated), heterozygote, and heal

45 Untreated and oxotremorine-treated Gnal(+/-) mice provid

46 Our results also provide evidence that untreated and oxotremorine-treated Gnal-haplodeficient m

47 ells conferred rapid cytolysis of previously untreated and R/R primary myeloma cells in vitro.

48 ty of intravenous ofatumumab monotherapy for untreated and relapsed Waldenstrom's macroglobulinaemia.

49 ts exhibited similar green hue to those from untreated and steamed leaves, while zinc-chlorophylls ex

50 y against combined acid-heat than those from untreated and steamed leaves.

51 ressed rat cardiac cells as well as from the untreated and treated breast cancer cells.

52 o-toe verbal interview to determine existing untreated and treated surgical conditions.

53 non-responder tumors showed that compared to untreated and treatment-sensitive tumors, treatment sens

54 Most patients remain undiagnosed, untreated, and die.

55 Additionally, compared with untreated animals, animals that received G-CSF following

56 C2-like MDA-MB-231 cells dominated in untreated animals, but C3-like MCF7 cells were selected

57 ignificantly greater memory impairments than untreated animals.

58 formed whole-transcriptome RNA sequencing of untreated, apoptotic, and recovering HeLa cells.

59 in the SS31-treated APP mice relative to the untreated APP mice.

60 Seven minutes of untreated arrest was followed by resuscitation.

61 Untreated B6-Cd14(-/-) mice and wild-type controls did n

62 ed by pre-incubation of sensory neurons from untreated BALB/c mice with 0.0001% HOCl.

63 rats treated with LIP ultrasound than in the untreated BCCAO rats (mean, 94.5% +/- 2.3 [standard erro

64 ease kinetics values from predisinfected and untreated biofilms under flow condition were not statist

65 edisinfected biofilms) or disinfectant-free (untreated biofilms) conditions, respectively.

66 reedom was defined as no current smoking and untreated blood pressure <140/90 mm Hg, fasting glucose

67 e safety profile in patients with previously untreated BRAF(V600E)-mutant NSCLC.

68 Transcriptome analysis of treated and untreated C. albicans using Gene Ontology (GO) revealed

69 In contrast to untreated C57Bl/6, L-NAME decreased placental sO2 at GD1

70 Ocular infections, if left untreated, can damage the structures of the eye with pos

71 (NASH) in AYAs often go unrecognized and, if untreated, can progress eventually to cirrhosis requirin

72 obtained during induction of cardiac arrest, untreated cardiac arrest, and resuscitation.

73 met need, and there are many undiagnosed and untreated cases of DR.

74 ced the incidence of keratitis from 15.8% in untreated cases to 1.9% in treated cases (P = 0.056).

75 and had histologically confirmed, previously untreated, CD20-positive grade 1, 2, or 3a follicular ly

76 In most untreated cell types, the majority of STAT2 is phosphory

77 -field imaging of numerous drug-treated and -untreated cells (N = 240,000) by optofluidic time-stret

78 ntified differences between ROCK-treated and untreated cells as early as 12 hrs.

79 ls overexpressing these tsRNAs compared with untreated cells, confirming that tsRNAs affect cell grow

80 ve correlations in cycloheximide-treated and untreated cells.

81 orescence signal from (18)F-FDG-treated than untreated cells.

82 ered HR protein dynamics in both damaged and untreated cells.

83 5' leaders in both cycloheximide-treated and untreated cells.

84 ion, and increased p62 level compared to MPA-untreated cells.

85 tory potential of HA-treated MSC compared to untreated cells.

86 s and equivalent migration speed relative to untreated cells.

87 s were ineligible if they had symptomatic or untreated central nervous system metastases, had receive

88 Untreated childhood cerebral adrenoleukodystrophy (cALD)

89 nalyses do not suggest indirect benefits for untreated children from being exposed to treated childre

90 Rigorous estimates for clearance rates of untreated chlamydia infections are important for underst

91 ne related to untreated diarrhoea and one to untreated cholelithases/liver disease) and one in the ge

92 l crevicular fluid (GCF) among patients with untreated chronic periodontal disease.

93 Patients and Methods Eligible patients had untreated clear cell mRCC and Eastern Cooperative Oncolo

94 k, and perinecrotic regions of 13 previously untreated, clinically-annotated and genetically-defined

95 r the two bioconverted coals compared to the untreated coal.

96 The DeltapHe was significantly higher in untreated compared to treated rats (p < 0.002), suggesti

97 ase in serine-ADP-ribosylation in vivo under untreated conditions as well as following hydrogen perox

98 contacts, and 5 presented outcomes only for untreated contacts.

99 omposition experiment on lake water, with an untreated control and a treatment preexposed to UV light

100 3% reduction in tumour volume relative to an untreated control group (p<0.05) when the tumour was exp

101 n was increased by up to 35-fold that of the untreated control.

102 i resulted in maturation 57% faster than the untreated control.

103 plus IRE; five rabbit VX2 tibial tumors were untreated (control group).

104 nate-treated controls (median, 2254 AU), and untreated controls (median, 239 AU) (P < .03).

105 ved to 18 months of follow-up, compared with untreated controls (P < .001).

106 fish had gene expression profiles similar to untreated controls of the same sex, indicating that they

107 ing of unlasered TM in ExGl eyes compared to untreated controls was observed.

108 treatment group (PrOD, 0.3%; LDV/SOF, 1.4%; untreated controls, 2.5%; P < .001).

109 rs after treatment to levels comparable with untreated controls, whereas calcium content endured at h

110 vement in erythrocyte morphology compared to untreated controls.

111 rsity, and functional repertoire compared to untreated controls.

112 reduced apoptosis and mortality compared to untreated controls.

113 cells expressing CD62L in LNs compared with untreated controls.

114 treatment with nanoceria at pH 9 compared to untreated controls.

115 ntracellular Fe levels, relative to those of untreated controls.

116 t lowered total plaque burden by >60% versus untreated controls.

117 ity and CD45 biomarker retention compared to untreated controls.

118 al management strategies than HEDS, and left untreated could contribute to the pain or even physical

119 lear separation of HTST-treated samples from untreated counterparts as observed from analysis of prin

120 cator of periodontal access surgery needs in untreated dentition sextants but markedly overestimated

121 reference); (2) treated depression; and (3) untreated depression adjusting for demographics, AMI sev

122 he prognosis of patients with treated versus untreated depression differs.

123 In contrast, the 528 patients with untreated depression had higher 1-year mortality in comp

124 association may be confined to patients with untreated depression.

125 of increased drug clearance in patients with untreated diabetes.

126 red in the dacomitinib group (one related to untreated diarrhoea and one to untreated cholelithases/l

127 dual, but not universal, and the duration of untreated disease is the best predictor of stricture ris

128 Methods Patients with previously untreated DLBCL or other aggressive B-cell lymphoma were

129 graphy-computed tomography in 108 previously untreated DLBCL patients who received four 375 mg/m(2) r

130 do not respond to conventional CRT or remain untreated due to an inability or impediment to coronary

131 tion halted epilepsy progression relative to untreated epileptic mice; the latter showing a significa

132 ack of substantial IOP effects on the fellow untreated eye, compared to brimonidine twice-daily eye d

133 e foveal center increased by 3.1 mum/week in untreated eyes and 7.2 mum/week in bevacizumab-treated e

134 acizumab or laser photocoagulation (LPC) and untreated eyes.

135 howed tumor seeds morphologically similar to untreated eyes.

136 (odds ratio, 0.07; P = 0.024) compared with untreated eyes.

137 One untreated Fabry female and two treated Fabry females pre

138 icantly shorter than that of the previous 88 untreated facial attacks in the same women (mean: 64.1 h

139 ng SLs in OM-treated fibers when compared to untreated fibers; however, the magnitude of increase in

140 The incorporation of free and thermally untreated forms resulted in yogurts with higher initial

141 tion (SSC) and SSC/TA ratios were highest in untreated fruit.

142 olunteers and patients with newly diagnosed, untreated glioblastoma enabled visualization of brain gl

143 ated slower MF progression compared with the untreated group (mean [SD] increase of 3.1% [7.4%] vs 10

144 ortion of persons who died was higher in the untreated group compared with either treatment group (Pr

145 s estimated by comparing between treated and untreated groups by using Cox proportional hazards model

146 ified differences between EBOTAb-treated and untreated groups.

147 analysis was performed to match treated and untreated groups.

148 en and decreased host survival compared with untreated GSCs in orthotopic xenografts.

149 patients and treated patients compared with untreated HCV patients.

150 ts (540 with spontaneous HCV clearance, 1294 untreated HCV RNA positive, 345 treated with sustained v

151 ed from patient hemangiomas (HemECs) but not untreated HemECs readily differentiated into adipocytes

152 cific CD4(+) T cell responses in a cohort of untreated HIV clade C-infected persons.

153 T to prevent losses in HRQoL that occur with untreated HIV progression.

154 Lymph node cells from untreated HIV-infected individuals revealed that TFR cel

155 CI: 1.2, 1.9) times higher in treated versus untreated homes, when the probability that a pesticide w

156 Using 70 kDa dextran as a probe, untreated HUVECs yielded a Pd that approximated tumor va

157 Participants with untreated hypertension were enrolled from four centres i

158 hy, hepatocellular carcinoma, severe anemia, untreated hypothyroidism, Addison syndrome and major dep

159 t the end of the intestinal digestion in all untreated IF model systems.

160 pression, or referral for counseling, and as untreated if none of these 3 criteria was documented in

161 nome-wide association study of IOP in 69,756 untreated individuals of European, Latino, Asian, and Af

162 Among untreated individuals, including both elite controllers

163 Study of previously untreated infants with IH conducted at the ophthalmology

164 (2DG), lesions were diminished compared with untreated infected controls.

165 By contrast, compared with infants with untreated infection, antibiotic use during infancy was n

166 tissues assumed an M2 phenotype, compared to untreated infections which contained predominately M1 ma

167 data set included fluorescence EEMs from 291 untreated, irradiated (253.7 nm, 310-410 nm), and oxidiz

168 Left untreated, jaundice can lead to neurological impairment

169 Total antioxidant capacity of untreated juice was found to be 16% less than treated ju

170 steroid-regulated gene silencing complex) in untreated LCLs from women with PMDD, with more than half

171 In untreated LCLs, our results overall suggest a divergence

172 mbined acid-heat was compared with that from untreated leaves and synthetic colorant.

173 nd preservation of glucosinolate (85% of the untreated level) was obtained after HP treatment at 600M

174 Patients with untreated low-volume low-grade prostate cancer (clinical

175 ale rats pretreated with different inducers; untreated male monkeys, guinea pigs, rabbits, and hamste

176 ls when cultured using both HTST-treated and untreated media formulations.

177 Untreated metastases predominantly show increased (18)F-

178 adults (>/=18 years of age) with previously untreated metastatic BRAF(V600E)-mutant NSCLC were enrol

179 erability, supporting its therapeutic use in untreated metastatic urothelial cancer.

180 not differ significantly between treated and untreated mice after body weight rebound, suggesting tha

181 or growth in nude mice compared with control untreated mice or either drug alone.

182 arasitic female worms compared with infected untreated mice.

183 s and markedly improves survival compared to untreated mice.

184 ound in high numbers in MPA-treated, but not untreated, mice.

185 th corticosteroids but were also elevated in untreated, mild-to-moderate disease compared with health

186 mness and reduced gelation times compared to untreated milk.

187 y treated mothers, compared with 13.2% among untreated mothers (P = .019; chi2).

188 negative PCR results, compared with 32.2% of untreated mothers.

189 nd that transplant of fecal material from an untreated mouse abolished the protective effect of micro

190 osis incidence, a 242% increase in prevalent untreated multidrug-resistant tuberculosis, and a 275% i

191 r response rates in patients with previously untreated multiple myeloma who were not planned for imme

192 h consecutively treated eyes with previously untreated nAMD.

193 ated to consume on average 0.66 Anisakis per untreated (non-frozen) raw or marinated anchovy meal.

194 at 24 h and 21 d compared with contralateral untreated, nondenuded CCA.

195 Some irradiated corneas remained untreated or buffer treated.

196 ons of the cervical epithelium and stroma of untreated or estrogen-treated nontransgenic and HPV-tran

197 Model 1: incubation of untreated or hTNFalpha-treated PAEC with 10% human plasm

198 Coating of untreated or hTNFalpha-treated PAEC with CHC (100 microg

199 ace expression of costimulatory molecules by untreated or inhibitor-treated (bafilomycin and cytochal

200 ment of inhibitors in a cohort of previously untreated or minimally treated patients with hemophilia

201 rs) with type 1 or 2 diabetes and previously untreated or post-laser treated active proliferative dia

202 ed at least 18 years who were diagnosed with untreated or relapsed Waldenstrom's macroglobulinaemia a

203 (PCA) was used for classification of samples untreated or treated and treated at different treatment

204 ies next to raspberry crops that were either untreated or treated with the neonicotinoid thiacloprid

205 The number of people with untreated oral conditions rose from 2.5 billion in 1990

206 s (n = 104), (2) RDT-negative children whose untreated P. falciparum infections were detected retrosp

207 ence (HR 0.52, P < 0.001) compared with both untreated patients (69%; P = 0.010; HR 1.0) and treated

208 onstrated increased recurrence compared with untreated patients in multivariate analysis controlling

209 f the initial biologic therapy in previously untreated patients is unknown.

210 e-specific survival rate of 97%, whereas for untreated patients the survival rate was 94%.

211 the crude 1-year survival for treated versus untreated patients was 79% (95% confidence interval [CI]

212 DAA-treated and untreated patients were similar for sex distribution, IP

213 aterials and Methods The authors analyzed 61 untreated patients with a bulky lymphoma (at least one t

214 enib plus trametinib treatment in previously untreated patients with BRAF(V600E)-mutant metastatic NS

215 Under the above conditions, monocytes from untreated patients with CAPS undergo more efficient DNA

216 Participants were untreated patients with chlamydia from genitourinary med

217 lamydia from genitourinary medicine clinics, untreated patients with chlamydia from six areas in Engl

218 ce-daily oral dasabuvir 250 mg in previously untreated patients with chronic HCV genotype 1b infectio

219 5, 2012, and March 15, 2016, 468 previously untreated patients with chronic lymphocytic leukaemia we

220 Previously untreated patients with ES SCLC were randomly assigned i

221 METHOD: Nineteen untreated patients with first-episode psychosis (14 of t

222 lateral prefrontal cortex and hippocampus of untreated patients with first-episode psychosis.

223 ence of HCC-derived CTCs in nine of 16 (56%) untreated patients with HCC versus one of 31 (3%) patien

224 8-week treatment options for previously untreated patients with HCV genotype 1b infection withou

225 cant differences in CAL and PD compared with untreated patients with hypertriglyceridemia.

226 America and Europe, we recruited previously untreated patients with locally advanced or metastatic u

227 rednisone (R-CHOP) on outcomes in previously untreated patients with non-germinal center B-cell-like

228 teen studies with 16 datasets comprising 353 untreated patients with OSA and 444 healthy controls wer

229 ssive therapy with eltrombopag in previously untreated patients with severe aplastic anemia.

230 the protocol-defined population (previously untreated patients).

231 orticosteroids before surgery, compared with untreated patients, a finding that we confirmed in the e

232 argely reflects that of the primary tumor in untreated patients, and PDAC driver mutations are shared

233 reatitis, with a mortality rate of 20-43% in untreated patients.

234 events during treated periods compared with untreated periods.

235 n LDV/SOF, and 6970 propensity score-matched untreated persons.

236 Control experiments were performed with untreated plants and the obtained electrochemical result

237 xpression of ESC/E(Z) genes was decreased in untreated PMDD LCLs with MTF2, PHF19 and SIRT1 all signi

238 ease in type 2 fibers in treated compared to untreated portacaval anastomosis rats.

239 d significant signal enhancement compared to untreated PPDO sutures.

240 ain irradiation, as well as in patients with untreated primary brain tumors.

241 gas scenario where all fracturing fluid and untreated produced water is discharged directly to surfa

242 nitiation of treatment, and long duration of untreated psychosis (DUP) is associated with poor clinic

243 98, p=0.001, CI -4.74 to -1.21), duration of untreated psychosis (t=-0.86, p=0.031, CI -1.65 to -0.08

244 vulnerable groups with very long duration of untreated psychosis confirm the need for earlier interve

245 pport improved over time but the duration of untreated psychosis was not linked with the rate of impr

246 Relapse, untreated psychosis, intolerable side effects and the la

247 diagnosed, rifampicin-sensitive, previously untreated pulmonary tuberculosis were randomly assigned

248 and lower barrier permeability than those in untreated rats.

249 Collateral flow index in the untreated RCA and left coronary artery changed from 0.07

250 hat affects children and adults and that, if untreated, results in premature death.

251 In contrast, dendrites in untreated retinae degenerated slowly after the axonal tr

252 ed (28 days; 5 mg/kg, oral, twice daily) and untreated rhesus macaques.

253 d two RP mouse models to test whether dying, untreated rods negatively impact treated, rescued rods.

254 In one model, treated and untreated rods were segregated.

255 ing retinas that are a mosaic of treated and untreated rods, as well as cones.

256 atured HLA was expressed as HC-10 binding to untreated SAB as a percentage of maximal binding to acid

257 muM) results in a G2/M arrest compared with untreated samples, indicating significant DNA damage.

258 creased biofilm mass as compared to control, untreated samples.

259 t substantially reduced relative to those of untreated samples.

260 IgE cross-linking capability of treated and untreated samples.

261 l serum from clozapine-treated and clozapine-untreated schizophrenia groups are well correlated to ce

262 servation of myrosinase activity compared to untreated seedlings was after HP at 100MPa, 30 degrees C

263 Sanitary sewer overflows (SSOs) occur when untreated sewage is discharged into water sources before

264 in the presence of only suspended biomass in untreated sewage.

265 Compared to untreated sprouts, total isoflavonoid, PAL activity and

266 omly assigned, in a 1:1 ratio, patients with untreated stage IV or recurrent NSCLC and a PD-L1 tumor-

267 erent and higher than those of extracts from untreated/steamed leaves and synthetic colorant.

268 We show that untreated subjects develop different Class III craniofac

269 longitudinally in nine chronically infected untreated subjects with plasma viremia of <3,000 RNA cop

270 hasone, and rituximab (BDR) in 59 previously untreated symptomatic patients with Waldenstrom macroglo

271 thout CAD, and patients with severe CAD left untreated (TAVR+PCI: 10.4%; severe CAD left untreated: 1

272 of the areas including treated and adjacent untreated teeth improved from T2 to T3 (P <0.001).

273 conducted among 37 consecutive patients with untreated thyrotoxicosis (25 female and 12 male; mean ag

274 e from painless thyroiditis in patients with untreated thyrotoxicosis.

275 2)(+) responsiveness, which was depressed in untreated Tm-E54K mice.

276 ization was assessed in a cohort matched 2:1 untreated to treated based on age and propensity score.

277 in 6 months of diagnosis (and were otherwise untreated) to advanced stage patients with HCC who recei

278 If left untreated, TR can progress and result in progressive rig

279 surface treatment to make them slippery than untreated traps,

280 Immunohistochemical analysis of untreated tumors confirmed that C2 cells were invariably

281 umors with acquired resistance to HDM201 and untreated tumors identified 87 genes that were different

282 cation of primary treated tumors and distant untreated tumors in some mice implanted with the MB49 bl

283 s 0.116+/-0.047s(-1)) in treated compared to untreated tumors, the tracer was retained after treatmen

284 eased carotid IMT in children with HeFH than untreated unaffected siblings.

285 In Protocol 2, Nx rats remained untreated until Day 60, when they were divided into: Nx+

286 ptera stings can cause severe anaphylaxis in untreated venom-allergic patients.

287 Of 10 ambulatory patients, 5 died from untreated VF, 4 had cardiac arrests requiring external s

288 m NBUVB-treated vitiligo bulge compared with untreated vitiligo bulge.

289 en and caffeine, anthropogenic indicators of untreated wastewater discharges.

290 ate a model predicting the transformation in untreated wastewater of six biomarkers, excreted followi

291 -specific mitochondrial DNA (mtDNA) from raw untreated wastewater samples.

292 stewater systems (to halve the proportion of untreated wastewater), and existing system replacement,

293 tment (Target 6.3: halving the proportion of untreated wastewater).

294 PCB) congeners in surface water, treated and untreated wastewater, landfill leachate, and biosolids (

295 icantly younger in epigenetic age than their untreated, wild-type age-matched controls.

296 ingle LNCaP prostate cancer cells treated or untreated with androgen after cell-cycle synchronization

297 patients with severe hemophilia A previously untreated with FVIII concentrate, 197 with null mutation

298 tic triple-negative breast cancer previously untreated with systemic therapy were recruited from 44 h

299 imilar inflammation and injury in previously untreated WT and TLR4-KO mice.

300 reated solid and 13.8 times higher than with untreated yellow poplar.