コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 telomeric duplexes that are otherwise poorly unwound.
2 to the substrates that were the most readily unwound.
3 tly more than one ATP molecule per base pair unwound.
4 es in the 5' untranslated region of mRNA are unwound.
5 hese structures, the SH1 helix is seen to be unwound.
6 icates that the U5-IR stem becomes partially unwound.
7 in initial rate and maximum amount of duplex unwound.
8 and nucleic acid that forms as duplexes are unwound.
9 as the double helix melts, and before it is unwound.
10 hile hydrolyzing approximately 5 ATPs per bp unwound.
11 teraction of a Chi site contained within the unwound 3' ss-DNA tail with the RecC subunit during DNA
13 wounded (277+/-15 microm) compared with the unwounded (356+/-6 microm) corneas (P=0.0008) after 16 w
14 nd competitor DNA concentrations, the enzyme unwound 44% of F21:HF31 that was initially bound to the
15 ing, whereby the AdnA nuclease processes the unwound 5' strand to liberate a short oligonucleotide pr
16 of the panhandle structure by N protein, the unwound 5' terminus likely remains transiently bound to
21 y base pairs it has unwound, and once it has unwound a critical length, it reverses the unwinding rea
23 However, Pif1 working with pol delta readily unwound a full-length Okazaki fragment initiated by a fo
26 sodium-coupled transporter, LeuT, define an unwound alpha-helix as the central element of the ion-bi
27 isoforms and similar cleavage efficiency of unwound alpha1(I) and alpha2(I) chains suggested increas
28 ure would need to adopt an unusual, slightly unwound, alpha11/3 helix conformation (three complete tu
31 hyrin bound, the pi helix is not extended or unwound and is in the "substrate-bound" conformation.
35 origins are recognized, the DNA molecule is unwound and the replicative helicase is loaded onto the
36 rnover conditions, although the substrate is unwound and the repressor displaced when the single-stra
37 bubble expands downstream until 18 bases are unwound and the RNA is at least 7 nt long, at which poin
38 e further showed that blunt dsRNA is locally unwound and threaded through the helicase domain in an a
40 for the monocyte-specific antigen CD11b, in unwounded and epithelial scrape-wounded mouse corneas.
41 NK, M-CSF, and OPG proteins were detected in unwounded and wounded mouse corneas by immunocytochemist
42 RI (ALK-5) and RII co-localized in both the unwounded and wounded skin and was present in the same c
43 P mRNA expression in uninfected (wounded and unwounded) and in wounded corneas inoculated with P. aer
44 BLM can 'measure' how many base pairs it has unwound, and once it has unwound a critical length, it r
45 stalled forks are actively dechromatinized, unwound, and repressed by an ATR-dependent checkpoint pa
53 ning the present tetrahydroepoxide adduct is unwound at the lesion site, whereas the diol epoxide add
54 e triple helical structure has to be locally unwound before hydrolysis, but this process is not well
55 , defined as the average number of basepairs unwound between two successive rate limiting steps in th
56 defined as the average number of base-pairs unwound between two successive rate-limiting steps repea
59 suggest that, at least in MuLV, the tRNA is unwound by either the Gag protein or a cellular protein
60 the tRNA acceptor stem is not substantially unwound by NC in the absence of the RNA genome, that is,
63 rminated with 3'-ssDNA; however, such DNA is unwound by RecQ to create ssDNA for RecJ exonuclease.
65 s were functional RNAs (ribozymes) that were unwound by the helicase, and the first synthesised prote
69 are well separated from the promoter region unwound by the XPB DNA helicase and extend, respectively
71 e rate of formation and the stability of the unwound complex depend profoundly on supercoiling and th
72 ty DnaA binding sites to a completely loaded unwound complex, increasing both the precision of DNA re
75 hat all three DNA strands adopt extended and unwound conformations similar to those of RecA-bound dsD
78 and that the degree to which the template is unwound contributes importantly to the stability of the
83 < 0.01) fewer gammadelta T cells resident in unwounded corneal epithelium, which failed to increase i
84 mRNA was detected in uninfected (wounded and unwounded) corneal tissues and appeared to decrease in a
87 KL, M-CSF, and OPG proteins were detected in unwounded corneas, but were expressed at higher levels i
90 ansfer experiments (from wounded cultures to unwounded cultures) confirmed the existence of a soluble
91 to a novel conformation, that of a slightly unwound, curved, planar amphipathic alpha 11/3 helix (th
95 g H. pylori addA(NUC)B or addAB(NUC) mutants unwound DNA but had approximately half of the exonucleas
96 the time-course for formation of completely unwound DNA displayed a distinct lag phase that increase
97 varying size, we demonstrate that all of the unwound DNA generated at a stalled replication fork can
98 creased with duplex length because partially unwound DNA intermediate states are highly populated dur
99 ions affect the generation of a distorted or unwound DNA intermediate that has been implicated in hai
100 lecting the transient formation of partially unwound DNA intermediates during unwinding catalyzed by
104 function of this protein is to stabilize the unwound DNA or to aid lesion unwinding in preincision co
106 in the assimilation and stabilization of the unwound DNA strand, thus facilitating translocation of t
107 , MTERF1 binds a significantly distorted and unwound DNA structure, exhibiting a protein conformation
109 this region of T antigen provides the proper unwound DNA substrate for initiation to occur, we demons
111 ide (27), both of which also inhibited top2, unwound DNA, and are assumed to be DNA intercalators.
112 ular Cell, heterodimerizes with FANCM, binds unwound DNA, and reveals how the Fanconi anemia core com
113 a distinct lag phase for formation of fully unwound DNA, indicating that unwinding occurs in discret
119 al ring-shaped T7 helicase molecules as they unwound double-stranded DNA (dsDNA) or translocated on s
126 o examine the fate of ORC when origin DNA is unwound during replication initiation, we determined the
127 vations suggest that most oriC copies become unwound during stationary phase, forming an initiation-l
134 ating epithelium, but rather in the adjacent unwounded epithelium of the cornea, with most cells bein
136 P-positive nerve density in both wounded and unwounded eyes compared with vehicle-treated corneas.
139 acunarity analysis effectively discriminated unwounded fibromodulin-null versus wild-type skin as wel
142 e number of degranulated MCs is increased in unwounded forearm and foot skin of patients with diabete
143 many genetic observations, the detection of unwound fork structures in vivo and the identification o
151 was in excess of the substrate, NS3 (500 nM) unwound >80% of a DNA substrate containing a 15-nucleoti
153 viously shown to bind to hormone as a partly unwound helix, forms a complete alpha-helix that displac
157 DNA hundreds of base pairs in length can be unwound in a nonreciprocal phase of the reaction, consis
159 helicase, i.e. the number of the base-pairs unwound in a single catalytic step is only 1.4(+/- 0.2).
164 amp opening allows DNA to be loaded into and unwound in the RNAP active-center cleft, that DNA loadin
165 mulated with a mechanism in which the DNA is unwound in two kinetic steps with rate constant of k(unw
166 positions a nucleosome, evidently partially unwound, in a structure that facilitates Gal4 binding to
167 esence of excess enzyme, the quantity of DNA unwound increased significantly as the length of the sin
170 way, small interfering RNAs (siRNAs) must be unwound into their component strands, then assembled wit
172 s manner while the second copies the already unwound lagging-strand template in a discontinuous manne
174 to the central channel of the N-tier and the unwound leading single-strand DNA traverses the channel
175 esized both in wounded leaves and in distal, unwounded leaves in response to herbivory or other mecha
176 The increase in PLA activity in the systemic unwounded leaves was biphasic in wild-type tomato plants
186 standard substrate for 3'-->5' helicases, is unwound much less efficiently by BLM and WRN than are th
189 the existence of two distinct states of the unwound nucleosome, which are accessible at physiologica
190 end of the triple helix, which may leave the unwound oligonucleotide susceptible to nuclease degradat
195 These studies also suggest that partially unwound or noncomplementary regions of DNA could be phys
201 ppears to be dictated by the geometry of the unwound part of the transmembrane (TM) helix 3, mostly a
203 s release to the cytoplasm provided that the unwound part of TM3 switches from a shielding to a yield
204 iencies of both wild-type (about 1 base pair unwound per dTTP hydrolysis) and mutant (4 to 6 base pai
207 ciently transferred this T-DNA into cells of unwounded plants in the absence of exogenous vir gene in
210 ites attention to the functional role of the unwound portion of TM helices (TM6 Trp-202-Glu-208 in Ad
211 athway between the sodium-binding sites, the unwound portion of transmembrane helix 1 and the substra
212 ound-induced (win) mRNAs are detected in the unwounded portion of that leaf and in specific leaves th
214 branch migration by RecA, where a completely unwound product consisting of the paired nascent leading
215 d SSB; however, RuvAB generates a completely unwound product consisting of the paired nascent leading
218 he ability of BC200 to act as an acceptor of unwound quadruplexes via a cytosine-rich region near the
219 oncentrations (1 nM), the bulk of the DNA is unwound rapidly by pre-bound UvrD complexes upon additio
225 ts in ARS1 and ARS307 but contains an easily unwound region whose functional importance was supported
226 of oriC, whereas DnaB fails to bind to this unwound region, the open structure is insufficient by it
230 RNA, thereby facilitating the release of the unwound rRNA mother strand and the recycling of DbpA for
232 omain (TM6a) that is separated by a central, unwound section from a cytoplasmically localized domain
234 ing, duplex unwinding and degradation of the unwound sense strand and RNA-induced silencing complex f
236 mptive DNA reaction intermediates containing unwound sequences 5' to, 3' to, or encompassing the DNA
237 cases, the complexes are characterized by an unwound SH1 helix first seen in an unusual 2.5-A scallop
238 ked its N-terminal RPA interaction site also unwound short DNA duplex substrates similar to wild-type
239 AdnAB helicase under conditions in which the unwound single strands are coated by SSB and thereby pre
240 ing a synthetic sequence that mimics freshly unwound single-stranded DNA at replication fork showed t
243 ge (80S), ATP-enhanced complex that contains unwound siRNAs, cofractionates with known RNAi factors,
244 ression was strongly increased compared with unwounded skin and the signal was localized to the wound
245 tral endopeptidase expression in wounded and unwounded skin as well as in cells derived from human sk
246 sion, the presence of nondegranulated MCs in unwounded skin is required for proper wound healing, and
247 undetectable in keratinocytes isolated from unwounded skin, but induced in cells following contact w
250 hemical localization of TGF-beta isoforms in unwounded skin, RI and RII were expressed throughout the
251 d skin, but not in ganglia that projected to unwounded skin, suggesting that neurons respond to a loc
256 g index (LI) that was markedly elevated from unwounded specimens in the first 48 h after abrasion.
257 nwinding and/or by POT1 loading on partially unwound ssDNA strands to prevent strand re-annealing.
258 vironment in the absence of the receptor, is unwound starting at T(32) to provide optimal contacts in
259 raps the recognition site 5'-CATATG-3' in an unwound state, permitting intercalation centrally and hy
262 r results demonstrate not only that multiple unwound states exist but that their accessibility can be
266 ity of WRN helicase by maintaining partially unwound strands in a melted state, rather than preventin
267 e, a serine and a main-chain carbonyl in the unwound stretch of trans-membrane helix 5 at the deepest
269 conjunctiva exhibited increases in LIs from unwounded subjects at singular timepoints (within 24 h o
270 ion did not require new DNA synthesis on the unwound template strand but did require RNA primer synth
271 es with high affinity (Ka > 10(8) M(-1)) and unwound the DNA duplex through intercalation (unwinding
273 anded DNA-binding protein, FANCJ efficiently unwound the DNA substrate harboring the thymine glycol d
275 ated that if the terminator DNA is partially unwound, the resulting melted DNA could bind tightly to
276 HrP helix is gently curved and C-terminally "unwound." The receptor accommodates the altered binding
277 -tail and the length of the duplex DNA to be unwound, this activity is sufficiently strong to mask th
282 ," and "highly curved." The rods can also be unwound to form thin "threads" that are very similar to
283 differ when sequences are presented from an unwound triple helix versus an independent single strand
286 ity on DNA polymers, showing that DNA can be unwound under extremely permissive conditions that favor
287 1 mRNA was undetectable in either wounded or unwounded, uninfected corneal tissues, but it increased
289 he amount of double-stranded DNA that can be unwound using the free energy derived from hydrolysis of
295 ucleotide (nt) 3'-tail and 35-nt 5'-tail was unwound with optimal rates close to 60 base pairs/s at 1
298 nded fou2 were found to be lower than in the unwounded WT, but they increased in a similar manner in
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。