ライフサイエンスコーパス: upregulate the expression of

1 ition to activating T3SS2(bp), HrpB(bp) also upregulates the expression of ~30 additional B. pseudoma

2 Based on three independent experiments, Act upregulated the expression of 34 genes involved in cell

3 HG treatment upregulated the expression of 41 genes and downregulated

4 ded protein response in Arabidopsis thaliana upregulate the expression of a constellation of genes de

5 o use a commonly used pharmacologic agent to upregulate the expression of a newly transferred gene on

6 inding-EGF-like growth factor (HB-EGF), that upregulate the expression of a patient-specific COL7A1 a

7 Further, TLR ligands upregulated the expression of a nociceptive receptor, tr

8 inhibit RapP activity or, more likely, PhrH upregulates the expression of a peptide that, in turn, d

9 i spirochetes express a novel activity which upregulates the expression of a variety of host cell che

10 hil numbers in the airways and significantly upregulated the expression of activation markers, TH2 in

11 (LTalpha) which acts on endothelial cells to upregulate the expression of adhesion molecules that are

12 aracteristic of their epithelial origin, and upregulate the expression of adhesion receptors that are

13 vascular endothelial cells (BMVECs) to CD40L upregulated the expression of adhesion molecules intrace

14 s to the metastatic phenotype of melanoma by upregulating the expression of adhesion molecules, prote

15 ons, the transcription factors STAT3 and AhR upregulated the expression of Aiolos, a member of the Ik

16 BMP2 (statistically significant at P <0.001) upregulated the expression of alkaline phosphatase and i

17 a time- and concentration-dependent manner, upregulated the expression of all 3 subtypes (1, 2, and

18 ve autoregulatory loop, where TrkB signaling upregulates the expression of all major BDNF transcripts

19 Considering that CYR61 is sufficient to upregulate the expression of alpha(v)beta(3), we then as

20 e, beta1-integrin null lens epithelial cells upregulate the expression of alpha-smooth muscle actin a

21 s ability to invade through fibronectin, and upregulates the expression of alpha3 (28%), alpha4 (90%)

22 INH and TLM, but not TRC, upregulate the expression of an operon containing five F

23 nes (AHLs) produced by Y. enterocolitica and upregulates the expression of an invasin (Rck) and a put

24 The possibility that glucocorticoids upregulate the expression of anti-inflammatory mediators

25 DHA upregulated the expression of anti-oxidative enzymes in

26 ntly decreased the intima-to-media ratio and upregulated the expression of aortic endothelial nitric

27 5) Lupus antigen-presenting cells fail to upregulate the expression of B7-1 (CD80) in response to

28 strains of T. gondii (types I, II, and III) upregulated the expression of B7-2, but not B7-1, on the

29 everal commonly used chemotherapeutic agents upregulated the expression of Bcl-x and/or Bfl-1/A1 thro

30 he depression-like behaviors of PSD mice and upregulate the expression of BDNF in the hippocampus.

31 In conclusion, GMF upregulates the expression of BDNF and NGF in C6 cells,

32 Treatment with RA upregulated the expression of both MUC4 and -16 mRNA and

33 Mechanistic studies showed that leptin upregulated the expression of both the spinal NMDA recep

34 Hypoxia upregulated the expression of both VCAM-1 and ICAM-1, wh

35 rtually all normal donors; and (6) that IL-3 upregulates the expression of both activating and inhibi

36 lear antigen (EBNA) 2 (EBNA2) is involved in upregulating the expression of both EBNAs and latency-as

37 mutant lacking the SH2 domain was unable to upregulate the expression of c-Myc and Bcl-2; in contras

38 High-dose probiotic upregulated the expression of C80, CD86, CD40, and major

39 uropathic pain development by binding to and upregulating the expression of CaV2.2.

40 nes such as TNF-alpha, IFN-gamma, and GM-CSF upregulated the expression of CD24 in vitro, favoring th

41 on of DCs with OmpA(+) E. coli significantly upregulates the expression of CD47, an integrin-associat

42 Although both maturing mDCs and pDCs upregulate the expression of CD80 and CD86, only pDCs up

43 acrophage colony-stimulating factor (GM-CSF) upregulated the expression of CD95 on PHPs upon in vitro

44 UV is known to transcriptionally upregulate the expression of certain genes by activating

45 al for downstream resistance events but also upregulates the expression of certain R genes.

46 ll to recover by attenuating translation and upregulating the expression of chaperones, degradation f

47 rough the general phenylpropanoid pathway by upregulating the expression of cinnamate-4-hydroxylase (

48 dium yoelii erythrocyte stage infection, APC upregulate the expression of class II MHC and CD80, main

49 hip profiling revealed that RIP140 depletion upregulates the expression of clusters of genes in the p

50 (+) mDCs could engulf S. aureus and strongly upregulated the expression of costimulatory molecules an

51 y activates human plasmacytoid DCs (pDCs) by upregulating the expression of costimulatory and MHC mol

52 eron-inducible transmembrane proteins, while upregulating the expression of critical EBOV entry facto

53 UPEC upregulates the expression of Cu efflux genes during cli

54 cription of all three CUC genes, whereas SYD upregulates the expression of CUC2.

55 In particular, NB cells upregulated the expression of CXCR4 and CXCR3 in all NK

56 F) activates mast cell migration, in part by upregulating the expression of CXCR4 on the surface of m

57 d geminin in infected cells, its capacity to upregulate the expression of cyclin E has been reduced.

58 siRNA knockdown of Cdx2 or Rbl2/p130 upregulates the expression of Cyclin E, OCT4 and SOX2, a

59 d with TMEV and that infection significantly upregulates the expression of cytokines involved in inna

60 adhesion, exhibit morphological changes, and upregulate the expression of cytoskeletal proteins.

61 n, idarubicin, and epirubicin) significantly upregulated the expression of death receptors (DRs) (TNF

62 odels, but we also found that canonical Wnts upregulated the expression of Dkk2 in osteoblasts.

63 TyrRS activates transcription factor E2F1 to upregulate the expression of DNA damage repair genes suc

64 The PROX1/KLF2 complex upregulates the expression of DTX1 and DTX3L.

65 Finally we show that MYOD can upregulate the expression of ebf genes, indicating the p

66 k-1, and C/EBPbeta, downregulates c-Jun, and upregulates the expression of egr-1, an ERK/SRE target g

67 these results, exogenous wild-type p53 also upregulates the expression of endogenous TRID in p53-nul

68 only the cytoplasmic domain of the protein, upregulated the expression of ER stress response genes i

69 units to form a transcriptional complex that upregulates the expression of ER stress-induced genes.

70 lysis revealed that 17beta-E(2) pretreatment upregulated the expression of ERbeta and phase II cellul

71 cellular content upon ligand stimulation and upregulated the expression of estrogen-responsive genes

72 We hypothesized that upregulating the expression of estrogen receptor alpha (

73 AP-1 transcription factors directly upregulate the expression of exon I transcripts by bindi

74 In cell culture, latent KSHV infection upregulated the expression of EZH2 in human endothelial

75 rane damage prior to mitochondria damage and upregulated the expression of Fas and Fas L, while the e

76 UVB irradiation significantly upregulated the expression of Fn14 on keratinocytes in v

77 to small doses of DNA-methylating agents by upregulating the expression of four proteins.

78 Mechanically, PS341 upregulated the expression of FOXO3, which inhibited the

79 es to corneal epithelial barrier function by upregulating the expression of functionally related subs

80 Progesterone (5 mg/kg, twice daily) upregulates the expression of GABA(A)R delta subunits an

81 Molecularly, we found that loss of Gpr126 upregulated the expression of Gal3st4, a gene implicated

82 roduction of tumor necrosis factor alpha and upregulated the expression of genes encoding interleukin

83 ntrast, chronic moderate alcohol consumption upregulated the expression of genes involved in immune r

84 ASA upregulated the expression of genes that could activate

85 In vitro, CD4(+) T cell activation upregulated the expression of genes that favor oxidative

86 cts these compositional changes and directly upregulates the expression of genes involved in the comp

87 As animals enter adulthood, EGF signalling upregulates the expression of genes involved in the ubiq

88 iptional changes caused by the stroke, while upregulating the expression of genes associated with axo

89 Here, we report that fasting upregulates the expression of Hap1 in the rodent hypotha

90 These data suggest that sebum FFAs upregulate the expression of hBD-2 in human sebocytes, w

91 We show that acid pH upregulates the expression of Hcp1 of T6SS-1 and TssM, a

92 GNP mitogens Jagged1 or Sonic Hedgehog (Shh) upregulates the expression of HES1, suggesting a role fo

93 show that autocrine production of TGF-beta1 upregulates the expression of Hic-5, which is essential

94 xerting a direct biological impact, cmvIL-10 upregulates the expression of hIL-10 by primary blood-de

95 rotected DNA from single-strand breakage and upregulated the expression of Hsp27.

96 barrier in co-cultured endothelial cells and upregulated the expression of ICAM-1 nine-fold.

97 LTC4 upregulated the expressions of ICAM-1 and VCAM-1 in an a

98 In addition, IL-3-induced STAT5 activation upregulated the expression of Id1 and Id2, which are neg

99 differentiated mDCs secreted type I IFN and upregulated the expression of IFN-stimulated genes (teth

100 e for a competition model to explain how Nef upregulates the expression of Ii at the cell surface.

101 etion of regulatory T cells in weanling mice upregulated the expression of IL-17A and CXCL9 in the lu

102 CD16 also upregulated the expression of IL-1R-associated kinase M

103 ILC2 activation through CRTH2 also upregulated the expression of IL-33 and IL-25 receptor s

104 Treatment with CD154, the ligand for CD40, upregulated the expression of IL-6, IL-8, and MCP-1 in T

105 hese sugar concentrations were sufficient to upregulate the expression of ILY, MsgA, and NanA.

106 e the expression of CD80 and CD86, only pDCs upregulate the expression of inducible costimulator liga

107 Administration of alpha-GalCer also upregulated the expression of inflammatory genes at the

108 Previously, we found that ATM mutants upregulate the expression of innate immune response (IIR

109 pe I interferons (IFN-I), which are known to upregulate the expression of innate restriction factors.

110 breast cancer cells, 17-beta-estradiol (E2) upregulates the expression of insulin receptor substrate

111 ons, Treg cells did not suppress, but rather upregulated, the expression of interleukin-17A (IL-17A),

112 ritic cells (BMDC) from TLR4-deficient mice, upregulating the expression of interleukin-12 and costim

113 lated intestinal blood flow and coordinately upregulated the expression of intestinal eNOS mRNA, prot

114 of CYR61 in HRG-negative MCF-7 cells notably upregulated the expression of its own integrin receptor

115 HI to the respiratory epithelium, therefore, upregulates the expression of its own receptor.

116 We also found that Cu deficiency upregulates the expression of jasmonic acid (JA) biosynt

117 Pellet cultures of hCSSC in serum-free media upregulated the expression of keratocyte-specific genes

118 or in co-infection with TYLCSV significantly upregulates the expression of key genes governing DNA me

119 that short-term exposure to a high-fat diet upregulates the expression of key genes involved in lipi

120 APRIL further amplified CLL cell survival by upregulating the expression of leukemic CD40L.

121 previously reported that interleukin (IL)-4 upregulates the expression of leukotriene C(4) synthase

122 EBNA2 upregulates the expression of LMP1 and other cellular ge

123 BER2 knockdown phenocopies PAX5 depletion in upregulating the expression of LMP2A/B and LMP1, genes n

124 ytokines without affecting IL-10 production, upregulated the expression of M2 polarization-associated

125 dramatically increased seizure frequency and upregulated the expression of many inflammatory proteins

126 he intestine and thought to be bactericidal, upregulates the expression of many ETEC virulence factor

127 K13 also upregulated the expression of Mcl-1, an antiapoptotic me

128 uce downregulation of adhesion molecules and upregulate the expression of metalloproteinases.

129 Glutamate exposure upregulates the expression of mGluR5 in hippocampal HT-2

130 cts directly on ectopic endometrial cells to upregulate the expression of MIF, which, in turn, displa

131 Moreover, Pbx1-d-Tg CD4(+) T cells upregulated the expression of miR-10a, miR-21, and miR-1

132 mpared to the VEH/SIV group, THC selectively upregulated the expression of miR-10a, miR-24, miR-99b,

133 reted bacterial antigens via its capacity to upregulate the expression of molecules involved in antig

134 opus Foxj1 induces the formation of cilia by upregulating the expression of motile cilia genes.

135 dies show that demethylating agents strongly upregulate the expression of mouse Rhox genes, suggestin

136 Furthermore, cancer cell-expressed MT1-MMP upregulated the expression of MT1-MMP in vascular endoth

137 coacervate stimulates cardiac fibroblasts to upregulate the expression of multiple trophic factors in

138 diates the angiogenic response to hypoxia by upregulating the expression of multiple angiogenic facto

139 usly defend against or repair this damage by upregulating the expression of multiple oxidative stress

140 stored the C/EBPalpha-C/EBPgamma balance and upregulated the expression of myeloid differentiation ma

141 ts, we investigated whether GMF-transfection upregulated the expression of neurotrophins in C6 cells.

142 K13 upregulated the expression of NF-kappaB subunit RelB and

143 ORF74 upregulated the expression of NF-kappaB-dependent inflam

144 pression in colorectal cancer cells strongly upregulated the expression of NKG2D ligands (NKG2DLs), M

145 ls in which we have shown that TSA alone can upregulate the expression of non-methylated genes.

146 chanistically, Notch1 activation in myotubes upregulates the expression of Notch ligands, which modul

147 ment in the mitochondrial matrix selectively upregulates the expression of nuclear genes encoding mit

148 Although C. phytofermentans upregulates the expression of numerous enzymes to break

149 Among four different EPs (EP1-4), infection upregulated the expression of only EP2, and individual a

150 Therefore, pharmacological agents that upregulate the expression of or prevent the degradation

151 This suggests that CspC and CspE upregulate the expression of OsmY and Dps by regulating

152 ole in the aerotolerance of P. gingivalis by upregulating the expression of oxidative-stress genes.

153 mitogen-activated protein kinase pathways to upregulate the expression of P-selectin in platelets, wh

154 hat CHOP/GADD153 may play a positive role in upregulating the expression of p21(WAF) in a p53-indepen

155 have shown recently that Tax can drastically upregulate the expression of p27(Kip1) and p21(CIP1/WAF1

156 hese findings suggest that both antimitogens upregulate the expression of p27(Kip1) as they prevent t

157 These data show that E7 upregulates the expression of p53 and p21 via pRb-depend

158 IKKalpha reduction upregulated the expression of p63, Trim29, and keratin 5

159 Moreover, far-red and blue light upregulate the expression of PCH1 and PCHL in a phyB ind

160 molecular mechanisms through which H. pylori upregulates the expression of plasminogen activator inhi

161 Induction of SSAT upregulated the expression of polyamine oxidase and resu

162 Honokiol upregulated the expression of PPARgamma in the mouse hea

163 ux, activated nuclear factor (NF)-kappaB and upregulated the expression of pro-inflammatory cytokines

164 h the combined effects of Ndk and flagellin, upregulates the expression of proinflammatory cytokines

165 vascular networks typical of KS vasculature; upregulates the expression of proinflammatory cytokines,

166 IL-4 upregulates the expression of protein arginine methyltra

167 sed expression of miR-21 and CSC markers and upregulated the expression of PTEN, which indicates that

168 a expression in skeletal muscle coordinately upregulate the expression of pyruvate dehydrogenase kina

169 In this study, we report that Ras activation upregulates the expression of Raet1 protein family membe

170 IL-17 upregulated the expression of regulator of G-protein sig

171 03(+) DCs, but not pDCs or lung macrophages, upregulated the expression of retinaldehyde dehydrogenas

172 , when it reduced adenyl cyclase activity by upregulating the expression of Rgs2, a GTPase-activating

173 Mechanistically, we showed that FoxOs upregulated the expression of Rictor, an essential compo

174 Accordingly, KSHV upregulated the expression of RTA (Orf50), a master tran

175 While XBF-2 does not upregulate the expression of secreted neural inducers, i

176 THP-1 cells exposed to Stx1 upregulate the expression of select dual-specificity pho

177 algU downregulated five polypeptides it also upregulated the expression of seven polypeptides as dete

178 ate with, and internalize, cryptococci, they upregulate the expression of several proteins involved w

179 hown that activation of PGI(2) receptor (IP) upregulated the expression of several contractile protei

180 shown that activation of PGI2 receptor (IP) upregulated the expression of several contractile protei

181 Gap19, a Cx43 mimetic peptide, significantly upregulated the expression of several MMPs, TGF-beta sig

182 IL-1alpha or TNFalpha upregulated the expression of several proinflammatory ch

183 , AtbZIP17 activation directly or indirectly upregulated the expression of several salt stress respon

184 human T-cell leukemia virus type 1 (HTLV-1) upregulates the expression of several cellular genes by

185 rosis factor pathway in the MCF10A cells but upregulates the expression of several genes implicated i

186 Array analyses indicated that ATF3 upregulates the expression of several genes in the tumor

187 toreceptor degeneration and at the same time upregulates the expression of several neurotrophic facto

188 In addition, we have found that SND1 upregulates the expression of several transcription fact

189 ytosolic DNA-activated dendritic cells (DCs) upregulate the expression of SLAMF2 molecules.

190 also evolved the ability to downregulate or upregulate the expression of specific cellular miRNAs to

191 ic lung infection and secondary alveolar H/R upregulate the expression of specific inflammatory cytok

192 mulation with immune complexes significantly upregulated the expression of sphingosine-1-phosphate re

193 ns respond to neutrophils via the Sae TCS to upregulate the expression of ssls.

194 Naive CD4 T cells from young adults upregulate the expression of STAT1 and STAT5 after activ

195 However, LXR also upregulates the expression of sterol regulatory element-

196 itivity to SDS and cell wall antibiotics and upregulating the expression of stress-responsive determi

197 phocyte-induced maturation protein (Blimp-1) upregulates the expression of syndecan-1 and J chain and

198 Tat also upregulates the expression of system xc-.

199 dition to the activation of innate immunity, upregulates the expression of T-cell co-stimulatory rece

200 oblast growth factor (bFGF)/heparin markedly upregulated the expression of TFPI activity and antigen.

201 We report here the ability of p73 to upregulate the expression of the A2B receptor, a recentl

202 Both HMGN3a and HMGN3b upregulate the expression of the glycine transporter 1 g

203 strains (Chlorella vulgaris YSL01 and YSL16) upregulate the expression of the hydrogenase gene (HYDA)

204 nsate for the lack of H3.3 in two ways: they upregulate the expression of the major histone H3 genes,

205 ing a proinflammatory response through TLRs, upregulate the expression of the NGF receptor TrkA.

206 aive, primary peritoneal macrophages rapidly upregulate the expression of the NK cell-surface marker

207 erentially to a classical T-cell mitogen and upregulate the expression of the pro-inflammatory cytoki

208 These cytokines have been shown to upregulate the expression of the Stx-binding membrane gl

209 er fibrosis, we demonstrate that hepatocytes upregulate the expression of the zinc finger transcripti

210 rotein amounts in the corneal epithelium and upregulated the expression of the anti-inflammatory IL-1

211 Activated endothelial cells upregulated the expression of the atypical chemotactic r

212 TG also upregulated the expression of the DR5 ligand TRAIL (tumo

213 Pg LPS upregulated the expression of the immune response-relate

214 Additionally, infected cells upregulated the expression of the negative T cell regula

215 Tpo upregulated the expression of the promoter conformation

216 Furthermore, infection upregulated the expression of the rate-limiting enzyme i

217 Furthermore, EFTUD2 upregulated the expression of the RIG-I-like receptors (

218 ortantly, improved motor neuron survival and upregulated the expression of the vascular endothelial g

219 and beta5 integrin subunit mRNAs as well as upregulates the expression of the alphavbeta3 integrin p

220 tion potently enhances seizure frequency and upregulates the expression of the chemokine CCL2.

221 crophages induces production of IL-10, which upregulates the expression of the immunomodulatory costi

222 Vav upregulates the expression of the interleukin-2 (IL-2) g

223 odeficiency virus type 1 (HIV-1) Nef protein upregulates the expression of the invariant chain (Ii)/m

224 In Vibrio vulnificus, HlyU upregulates the expression of the large RTX toxin gene.

225 Uniquely, Map4k4 silencing upregulates the expression of the myogenic regulatory fa

226 or liver X receptor (LXR), which in response upregulates the expression of the phagocytic receptor Me

227 that nornicotine, a metabolite of nicotine, upregulates the expression of the receptor for the advan

228 nd induce a cytokine response, which in turn upregulates the expression of the RNA helicases RIG-I an

229 I/RARgamma path in preadipose cells, thereby upregulating the expression of the adipogenesis inhibito

230 epithelial-to-mesenchymal transition and by upregulating the expression of the inflammatory cytokine

231 ase center (PTC) during its own translation, upregulating the expression of the protein translocase S

232 ell lines, but not in normal hepatocytes, by upregulating the expression of the splicing factors CUGB

233 e controls, ox-LDL stimulation significantly upregulated the expression of THP-1-derived macrophage M

234 Mechanistically, deletion of miR-15a/16 upregulated the expression of TLR4 via targeting the pri

235 Both UV-inactivated and untreated EBV upregulated the expression of TLR7 and downregulated the

236 -activated conjunctival mast cell supernates upregulated the expression of TNFR1.

237 ease in circulating free fatty acids did not upregulate the expression of transcription factors and g

238 d the expression of Crx, Nrl, and Nr2e3, and upregulated the expression of transcription inhibitors B

239 We found that the activation of TLR3 upregulates the expression of triggering receptor expres

240 Moreover, IFNlambda upregulated the expression of Tumor growth factor beta 1

241 studies suggest that angiotensin II (Ang II) upregulates the expression of tumor necrosis factor (TNF

242 In cultured mesothelial cells, TGF-beta1 upregulated the expression of VEGF-C mRNA and protein, a

243 atency-associated nuclear antigen (LANA) and upregulating the expression of viral cyclin and selectiv

244 ing attachment and effacement processes, and upregulating the expression of virulence genes and is al

245 Scl(-/-) endothelium also upregulated the expression of Wnt antagonists, which pro

246 es transcription from the BZLF1 promoter and upregulates the expression of Zta in permissive cells.