ライフサイエンスコーパス: upstream

1 bserved in Ackr4-deficient LNs to ACKR4 loss upstream.

2 ed tremor/ataxia syndrome is initiated at an upstream ACG near-cognate start codon.

3 argeting specificity of the binary GAL4-UAS (Upstream Activating Sequence) system by making GAL4 tran

4 fbp1 activation, Rst2 is first recruited to upstream-activating sequence 1 (UAS1), then it subsequen

5 These interactions include looping between upstream activation sequence (UAS) and promoter elements

6 ular signal-regulated kinase (ERK) 1/2 MAPK (upstream activators of MSK1) reduced MOR expression leve

7 4 signalling in brain endothelial cells, but upstream activators of this disease pathway have yet to

8 Nek6, as well as its upstream activators polo-like kinase 1 and Aurora-A, tar

9 rks for multiple ligands utilize independent upstream adaptive mechanisms, but common downstream targ

10 pseudoknotted element H4a/Psi3 required five upstream adenylates, and H4a/Psi3 was necessary for coop

11 Suction is transmitted upstream, allowing fluid to be drawn in through initial

12 geted methylation were observed around 25 bp upstream and 40 bp downstream of the PAM site, while 20-

13 ed 206 kb centered on HPRT1 (including 87 kb upstream and 79 kb downstream) with median 27-fold redun

14 -standing microelectrodes presenting passive upstream and downstream extensions and integrated into m

15 n of multiple pathway components acting both upstream and downstream of the mTOR kinase itself.

16 Sequence elements upstream and downstream of the RodZ transmembrane domain

17 nally, we will review treatments that affect upstream and downstream pathways related to inflammation

18 al and physiological features and connect to upstream and downstream synaptic partners.

19 ncoding ribosomal proteins, and the majority upstream and proximal ribosome binding sites, suggesting

20 have caused rapid ice-sheet thinning further upstream-and since the 1940s.

21 ten occurs even after flow is restored in an upstream artery.

22 th the RNA polymerase I transcription factor upstream binding factor (UBF).

23 Tau downregulation decreases upstream binding factor recruitment, ribosomal RNA synth

24 ized the polarization of afferent neurons in upstream brain regions may modulate activity in the targ

25 cial protection (potentially better provided upstream by keeping people out of the hospital rather th

26 PRMT5 expression was regulated upstream by the NF-kappaB pathway, and it promoted IL-2

27 tion in OZR may contribute to alterations in upstream capillary pressure profiles and the transcapill

28 aining the central Himalayan mountains, with upstream catchment areas ranging from about 350 to 50,00

29 nd implementation of policies to address the upstream causes of exclusion, such as adverse childhood

30 ies the set of covariance structures for the upstream cells that optimize the ability of information

31 e presence of HLA antibodies and complement, upstream complement anaphylatoxin production exacerbates

32 hese results highlight noncoding dsRNA as an upstream coordinator of prostaglandin and Wnt levels in

33 temporal firing patterns critically rely on upstream cortical input.

34 The analysis of transgenic 5' upstream deletion::gusA Arabidopsis lines showed that th

35 The structure shows how CAP wraps the upstream DNA and how the interactions recruit RNAP.

36 on termination is energy-dependent, requires upstream DNA sequences, and disrupts TECs to release the

37 genes that affect ABA levels and may act in upstream drought-related sensing and signaling mechanism

38 net chirality of all of their downstream and upstream edge modes.

39 a mode of translation control whereby, as an upstream effector of TOR, ROP2 coordinates TOR function

40 AF1 mediates ERK5 activity by regulating the upstream effectors of ERK5 and also by modulating its ub

41 ffects poly(A) signal recognition on the far-upstream elements; in particular it prefers less U-rich

42 We show that upstream emissions from urban household consumption are

43 ons and that local policy leverage to reduce upstream emissions is larger than typically assumed.

44 egulated by DNA methylation, including at an upstream enhancer that is protected by TET2, to allow Te

45 t (COL1A2), requires the engagement of a far-upstream enhancer, whose activation is strongly dependen

46 ets, supporting the likely involvement of an upstream epigenetic mechanism.

47 sonic hedgehog/patched interaction, the most upstream event in ligand-induced activation of this sign

48 sion period may be a critical and targetable upstream event in the injury cascade.

49 gnized function for TGF-beta signaling as an upstream factor controlling Treg cell activity in specif

50 IDS, but the exact role of C/EBPbeta and its upstream factors are not clear in HIV pain state.

51 eposits and neuronal apoptosis, the critical upstream factors contributing to p53 activation in AD ar

52 ively, the precise regulation of its gene by upstream factors has remained largely elusive.

53 he exact role of pC/EBPbeta and the detailed upstream factors of pC/EBPbeta in HIV-related pain.

54 s will represent different hidden sources of upstream firing activity.

55 Upstream from ERK, we show that PTP4A1 directly interact

56 nsulated from the variation in expression of upstream genes, and thus LRCs act as attenuators.

57 ter region and chromatin accessibility of an upstream genomic region with enhancer activity.

58 ation but rather only augmented signals from upstream in the cytokine pathway.

59 BP35 is known to form a dimer, and DRE2 acts upstream in the cytosolic FeS protein assembly pathway.

60 From upstream in the hierarchy to downstream, GBCs encompass

61 7, implying that these proteins may function upstream in the same pathway.

62 Upstream inhibition of classical complement may be thera

63 Upstream inhibition of STAT1 signaling with the small-mo

64 diaphragm muscle dysfunction (VIDD), but the upstream initiator(s) of this process remain to be eluci

65 Thus, upstream inputs interact with local mechanisms to determ

66 Here we examine the role of upstream inputs to PCs-excitatory granule cells (GCs) an

67 on health; (2) identifying opportunities for upstream intervention; and (3) working collaboratively t

68 t decades with associated thinning migrating upstream into tributaries feeding the main glacier trunk

69 We also found that IKKbeta, an upstream IRF5 activator, is phosphorylated in response t

70 this study explored the potential effects of upstream iron corrosion on lead mobility in water distri

71 the gravel sourced more than 100 kilometres upstream is converted into sand by the time it reaches t

72 Extension (KE) as it extends east of Japan ("upstream KE").

73 Despite a shared upstream kinase and similar phosphorylation sites, Cdr2

74 -GlcNAcylation disrupts its interaction with upstream kinase LATS1, prevents its phosphorylation, and

75 noncanonical NFkappaB pathway, including the upstream kinase mitogen-activated protein kinase kinase

76 , we demonstrate that inhibiting MEK1/2, the upstream kinases of ERK1/2 signaling, alters multifactor

77 h plant SnRKs are thought to be activated by upstream kinases, the overall mechanism remains obscure.

78 inct from the known binding sites for p38 or upstream kinases.

79 ization and phosphorylation by non-canonical upstream kinases.

80 t Taiwan, which occur synchronously when the upstream Kuroshio weakens during winter.

81 cardiac Sesn2 forms a complex with AMPK and upstream liver kinase B1 (LKB1) during ischemia.

82 bile salt (BS)-mediated toxic injury of the "upstream" liver parenchyma.

83 the binding affinity between Sesn2 and AMPK upstream LKB1 is impaired in aged hearts during ischemia

84 Further, mutants defective in the upstream MAP kinase kinase MKK3 also display hypersensit

85 er, these studies are the first to define an upstream mechanism regulating VHL suppression in cancer

86 Upstream, medial prefrontal cortical projections provide

87 ghlighting that afferent inputs are critical upstream mediators.

88 GM-CSF was identified as an upstream modulator.

89 atogenesis and suggests that this functional upstream molecular relationship can be exploited for the

90 yte development and neuronal marker) and its upstream molecule FIG4 (phosphatidylinositol (3,5)-bisph

91 rther suggest miR-24 could function as a key upstream molecule regulating TCF1-mediated immune respon

92 RRM2 binds to the upstream motif and RRM1 to the downstream motif.

93 ruler to template precise, regularly spaced upstream mRNA cleavage events.

94 disentangle superimposed firing patterns in upstream networks, and to represent their information co

95 support downstream charged modes as well as upstream neutral modes, and are expected to have a therm

96 festyle and risk factor management for AF as upstream noninvasive therapy.

97 her targeting deubiquitylating (DUB) enzymes upstream of 20S proteasome overcomes proteasome inhibito

98 vealed that transcription termination occurs upstream of a 5'-GCCAGCC-3' motif present in the virus g

99 cts with four separate native CATAC elements upstream of a basal promoter driving expression of eithe

100 In this study, two CWT plants 10 and 19 km upstream of a reservoir left geochemical signatures in s

101 cus, in a gene desert downstream of IRX1 and upstream of ADAMTS16.

102 cking EPH receptor A4 (Epha4KO/KO), which is upstream of alpha2-chimaerin in corticospinal neurons, e

103 king LKB1, a serine/threonine protein kinase upstream of AMPK, failed to activate AMPK and sustain en

104 mote dimerization and a conserved patch just upstream of an N-terminal Period/Arnt/Sim (PAS) domain,

105 tion pathway at multiple levels, acting both upstream of and downstream from her-1 to prevent aberran

106 ependent on glucocorticoid response elements upstream of annexins and was reinforced by the expressio

107 and on syntenin-syndecan endosomal budding, upstream of ARF6 small GTPase and its effector phospholi

108 Upstream of Atf4, BMP2 activates mTORC1 to stimulate pro

109 ase 1 (Plk1) also phosphorylates key factors upstream of ATM/ATR and regulates their DDR-related func

110 We found that NFAT1 upstream of ATX regulated expression of ATX as well as b

111 1-naphthylphthalamic acid (NPA) placed MED12 upstream of auxin transport for the sugar modulation of

112 and HPV-associated histone enrichment sites upstream of cancer driver genes, which play central role

113 hondrial function and cellular bioenergetics upstream of cellular damage may offer advantages compare

114 with proviruses containing lethal mutations upstream of CTL epitopes can also be recognized by CTLs,

115 tion of Panx3(-/-); Cx43(-/-) mice, Panx3 is upstream of Cx43 in osteogenesis.

116 opathy targeting intestinal mucosal immunity upstream of disease manifestation.

117 ex ERCC1-XPF is required for incision of DNA upstream of DNA damage.

118 recombination between two switch (S) regions upstream of each C region gene.

119 erved rheostat between long inverted repeats upstream of each exon.

120 , and this constraint is highest immediately upstream of genes.

121 truncated version of GmCLV1A was identified upstream of GmCLV1A that is absent from GmNARK, but is p

122 GSK-3beta activity, suggesting that OTG acts upstream of GSK-3beta.

123 highly conserved ERG-bound enhancer located upstream of HLX (which encodes a transcription factor im

124 lace SOD1-mediated inhibition of respiration upstream of its mitochondrial localization.

125 G levels could be produced from a gene 60 kb upstream of its normal telomeric location.

126 n or near transcription factor binding sites upstream of key genes implicated in maintaining physiolo

127 Indeed, extended GCC-box elements upstream of LFS drove primordia-specific expression in a

128 notypes, suggesting that MKK4/MKK5 might act upstream of MPK6 in this pathway.

129 subunit beta (IKKbeta), an activating kinase upstream of NF-kappaB.

130 ics, but the signaling pathways that operate upstream of Nkx factors in this context are not well und

131 ll death program initiating potassium efflux upstream of NLRP3.

132 position SoxF transcription factors directly upstream of Notch receptor expression during the acquisi

133 enetic evidence suggests that CPSF30-L works upstream of NRT1.1 and independently of NLP7 in response

134 onservation of putative NusB/E binding sites upstream of Nus factor genes suggests that Nus factor au

135 rial dynamics solely affect substrate supply upstream of oxidative phosphorylation.

136 both oranges, and the biosynthetic activity upstream of phytoene desaturase was similar in Newhall a

137 Furthermore, we show that Src is upstream of PI3K for activation of both IRF4 and Akt.

138 in prostate cancer, PSMA initiates signaling upstream of PI3K through G protein-coupled receptors, sp

139 ch as early focal adhesion kinase activation upstream of PI3K-mTOR, and induces transcriptional chang

140 of aerobic glycolysis must target reactions upstream of PKM.

141 tructure reveals that Rad26 binds to the DNA upstream of Pol II, where it markedly alters its path.

142 latory molecule in allergic asthma that acts upstream of proallergic events and suggest that targetin

143 cPKC is positioned upstream of Rac1 and the Arp2/3 complex, which activatio

144 e, pro-degenerative MAPK signaling functions upstream of SARM1 by limiting the levels of the essentia

145 TN2, DPP4 and MAST4) and one is found 200 kb upstream of SHH.

146 greater purifying selection relative to CGIs upstream of silenced genes.

147 MARCKS acted upstream of the AKT/mTOR pathway, activating HIF-target

148 f ATP8A2 consists of an autoinhibitor domain upstream of the C-terminal 33 residues and an anti-autoi

149 f R and U5, a poorly characterized structure upstream of the characterized HIV riboswitch and demonst

150 tion analysis, we identified a region 1.1 kb upstream of the CK5 transcriptional start site that is n

151 gement of miropin, which inserts the segment upstream of the cleavage site as an extra beta-strand in

152 of residues that overlap or are immediately upstream of the cleavage site.

153 esence of multiple small open reading frames upstream of the coding region.

154 t there is a coordinated balance of activity upstream of the corticospinal output neurons.

155 formed a functional dissection of the region upstream of the D. erecta eveS2 region and found multipl

156 e EPS regulatory pathway composed of the T4P upstream of the Dif signaling proteins in M. xanthus.

157 regulator of the Krebs cycle and is located upstream of the electron transport chain.

158 e the ZENV precursor to the membrane protein upstream of the envelope protein, and our rVSV-ZIKV cons

159 n the Severn River (UK), approximately 50 km upstream of the estuary (i.e. not "in the Severn Estuary

160 The primers target a region upstream of the FIP/BIP primer recognition sequences on

161 the transcription start site (TSS), which is upstream of the first protein-coding gene in the polygen

162 A that is absent from GmNARK, but is present upstream of the GmNARK orthologues, MtSUNN and PvNARK.

163 esence of G-quadruplex or i-motif structures upstream of the green fluorescent protein-coding sequenc

164 udinal transect of the South River, starting upstream of the historic Hg contamination point-source a

165 ly untranscribed sequences the same distance upstream of the intron as when the promoter was intact.

166 nsistently, Kabuki causative point mutations upstream of the JmjC domain do not disrupt UTX demethyla

167 ns a nuclease-hypersensitive element located upstream of the major transcription start site.

168 Of particular interest are lncRNAs upstream of the master chondrocyte transcription factor

169 ecipitation suggested that the -70 kb region upstream of the NGB gene contained a neuronal-specific e

170 Strikingly, PEAT is located just upstream of the Pax1 gene.

171 oncentration of TCE decreased from 300 mug/L upstream of the planted area to less than 5 mug/L downst

172 aversing the lamina densa tend to accumulate upstream of the podocyte glycocalyx that spans the slit,

173 rocess conditions (for example, malfunctions upstream of the point of emissions; equipment issues) ca

174 ped to the repeat regions of the VZV genome, upstream of the predicted promoter of the immediate earl

175 density of antisense transcribing polymerase upstream of the promoter region exhibited an increase in

176 potential Zap1 binding site located farther upstream of the promoter.

177 pathway, RDN1, functioning in the root, acts upstream of the receptor kinase SUNN, functioning in the

178 One lying upstream of the relaxin/insulin-like family peptide rece

179 ode progenitors using newly identified genes upstream of the Six/Eya complex.

180 x that spans the slit, but none are observed upstream of the slit diaphragm.

181 The 181-198 region of Qa, immediately upstream of the SNARE heptad-repeat domain, is required

182 ds on interaction between a sequence element upstream of the start codon (the Shine-Dalgarno sequence

183 e determined sequences extending nearly 2 kb upstream of the transcription start site for 68 alleles

184 nce of about 84 nucleotides (nt) immediately upstream of the Turnip crinkle virus (TCV) coat protein

185 r IPA3, suggesting that PAK1 activation lies upstream of these actin-polymerizing complexes.

186 intrinsic and extrinsic coagulation cascades upstream of thrombin and fX.

187 e associated with unpaired pre-mRNA segments upstream of U2AF-repressed 3'ss.

188 tion in Brachypodium distachyon That RVR1 is upstream of VRN1 is supported by the observations that V

189 ay indicated that the MybA protein functions upstream of wetA, vosA and velB, the key regulators invo

190 highlight TBX2 as a novel therapeutic target upstream of WNT3A, where WNT3A antagonists could be nove

191 we identified a novel Sertoli cell enhancer upstream of Wt1, and used it to drive expression of a tr

192 An upstream open reading frame (uORF) confers the translati

193 translation enhancing factor (PTEF) relieves upstream open reading frame repression and thereby facil

194 ession level of PTEF, and the alleviation of upstream open reading frame repression requires the prot

195 sion of a transcript variant lacking a small upstream open reading frame that would otherwise inhibit

196 so remains operational when combined with an upstream open reading frame.

197 in expression of Kozak sequence composition, upstream open reading frames (uORFs), and secondary stru

198 le promoter but also two pathogen-responsive upstream open reading frames (uORFsTBF1) of the TBF1 gen

199 ingle long transcript is produced with small upstream open reading frames in its 5' untranslated regi

200 rios, including the repressive effect of the upstream open reading frames on gene expression and the

201 This long RTC4 transcript contains small upstream open reading frames that prevent translation of

202 When bound upstream or within regulated exons PTBP1 tends to promot

203 he 5'-UTR also changes the inclusion of long upstream ORFs (uORFs).

204 elf cannot produce protein due to regulatory upstream ORFs in its extended 5' leader.

205 simple-cell-like receptive fields from their upstream partners.

206 hosphorylated C/EBPbeta (pC/EBPbeta) and its upstream pathway in the spinal cord dorsal horn (SCDH).

207 , indicating that IL-18R is a critical MyD88-upstream pathway involved in the establishment of the Th

208 gmentation, highlighting the significance of upstream primary metabolic regulation for the diversific

209 lity in the numbers of molecules involved in upstream processes, such as the intake of inducers from

210 ilatory genes, bind to adjacent sites in the upstream promoter region of the nitrate reductase gene,

211 embryos lacking Coup-tfII (chicken ovalbumin upstream promoter transcription factor II) in the Wolffi

212 Chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) ha

213 er mechanisms were involved, we knocked down upstream receptors GP130 or IL-2Rgamma.

214 One of several upstream receptors, cyclic GMP-AMP synthase, binds to cy

215 WTPs) (Waterloo, Kitchener), including three upstream reference sites.

216 Moreover, the upstream region of OsBZ8 gene has highly dynamic nucleos

217 An upstream region of the cers2b promoter supports enhanced

218 hese extended 3'-end regions than within PAS-upstream regions and indeed are substantially more folde

219 error, rather than inherit it passively from upstream regions; that they combine multiple separate an

220 Although the upstream regulation and downstream responses to GA vary

221 emonstrating that autophagy functions in the upstream regulation of integrin-mediated cell adhesion v

222 However, questions regarding the upstream regulation of the 53BP1 pathway remain unanswer

223 Pathways, functional and upstream regulator analysis of the intersections between

224 response gene PHOTOPERIOD1 (Ppd-H1) and its upstream regulator EARLY FLOWERING3 (HvELF3).

225 ng of a dicitrate transporter fecBCDE and an upstream regulator likely for iron uptake, whereas the o

226 As an upstream regulator of BCAT1 expression, we identified Mu

227 sive cytoplasmic adapter molecule that is an upstream regulator of both IkappaB kinase (IKK) and c-Ju

228 o persistent pain in EAE and functions as an upstream regulator of CaMKIIalpha signaling.

229 Oxygen (O2) acts as a potent upstream regulator of cell function.

230 nscription factor E2F3 (E2F3) as a prominent upstream regulator of cocaine-induced changes in gene ex

231 d a novel regulatory mechanism of MSI2 as an upstream regulator of ESR1 and revealed the clinical rel

232 uman peripheral blood cells and to define an upstream regulator of its activation through the release

233 itor of DNA binding protein 2 (ID2) as a key upstream regulator of KDR activation during myeloid diff

234 A2 transcription factor was identified as an upstream regulator of miR-194, consistent with a strong

235 hioredoxin-interacting protein (TXNIP) as an upstream regulator of miR-204, we also assessed whether

236 variants, we provide evidence that Nck is an upstream regulator of RhoA-dependent, MMP14-mediated bre

237 rved an attenuation of NF-kappaB pathway, an upstream regulator of the aforementioned genes, concomit

238 testicular development, thereby acting as an upstream regulator of the male pathway in P. sinensis.

239 rter of EMT, we discovered that S100A4 is an upstream regulator of the master EMT regulators SNAIL2 a

240 Our results define Rspo1 as a key upstream regulator of two crucial pathways necessary for

241 s response networks frequently have a single upstream regulator that controls many downstream genes.

242 (DNMT3a) in human cancer, the nature of its upstream regulator(s) and relationship with the master c

243 CN5L1 liver specific knockout mice and their upstream regulator, FoxO1 protein levels are decreased v

244 d that PO differentially regulates predicted upstream regulators and pathways, including LPS, members

245 We report the predicted upstream regulators and signalling pathways characterizi

246 Thyroid- and TH-associated upstream regulators as well as thyroid-related diseases

247 of the top diseases, functions, pathways and upstream regulators implied that a common underlying mec

248 known, relatively little is known about the upstream regulators of insulin transcription.

249 ) dual-specificity phosphatases as potential upstream regulators of ischemic neuronal death and Cdk4

250 Recently, oncogenic mutations in NRAS/KRAS, upstream regulators of the RAF/MEK/ERK pathway, have bee

251 y, to create membrane domains that partition upstream regulators of the TORC1 and TORC2 signaling pat

252 n factor that modulates the transcription of upstream regulators of WNT and MAPK-ERK signaling to saf

253 Upstream regulators that orchestrate this remarkable cha

254 triiodothyronine (reverse) were inferred as upstream regulators with differences in incidence and st

255 ied, little is known about the role of their upstream regulators, the Rho guanine nucleotide exchange

256 et there is little information regarding its upstream regulators.

257 bout how expression of Eya1 is controlled by upstream regulators.

258 t autophagy initiation complex (AIC) and the upstream regulatory components LKB1 and AMPKalpha, which

259 g/proximal promoter regions, but vary in the upstream regulatory regions.

260 lines were made by linking the promoter and upstream regulatory segments of CD79a and CD79b to enhan

261 proaches: "Orbital-deconvolution" elucidated upstream, regulatory pathways interconnecting human susc

262 e, across a spectrum of diverse, established upstream resistance mechanisms.

263 delivery to active muscle fibres by reducing upstream resistance via complementary signalling pathway

264 include factors that are proximately causal, upstream risk activators, and risk markers.

265 d muscular disorders, as well as networks of upstream RNA regulators.

266 ter-photobleaching experiments point for the upstream role of ezrin in stabilizing actin filaments at

267 Mps1 kinase is an upstream SAC regulator that promotes the assembly of an

268 The upstream SD sequence together with the hairpin promotes

269 gnaling pathways following the activation of upstream sensors in response to environmental stimuli.

270 d interfering with the recruitment of ASC to upstream sensors, which prevents caspase-1 activation an

271 We demonstrate that, in the absence of an upstream Shine-Dalgarno (SD) sequence, PoTC breakdown pr

272 and positioned is poorly understood, and the upstream signal to initiate asymmetric cell division is

273 5-kinases (PI4P 5-kinases) is controlled by upstream signaling is currently unknown.

274 Upstream signaling of C5a-mediated intracellular alkalin

275 However, the upstream signaling pathways governing LKB1 activation ar

276 -2K is regulated by Ca(2+) ions and multiple upstream signaling pathways, but how it integrates these

277 Further, we show that upstream signaling proteins have abundance-dependent eff

278 of genomic insults are well understood, the upstream signalling pathways that trigger repair are est

279 al milieu, human cells efficiently translate upstream signals into post-translational modifications (

280 led robust transcriptional responses to weak upstream signals.

281 DDB2 recruited EZH2 and beta-catenin at an upstream site in the Rnf43 gene, enabling functional int

282 during which it mediates initiation at these upstream sites, differentially skewing translation and p

283 on suggesting stronger nitrogen removal than upstream sites.

284 tes also had stronger carbon metabolism than upstream sites.

285 ld of health and human rights recognise that upstream social, political, and structural determinants

286 ng factor than black carbon or distance from upstream sources for long-chain perfluoroalkyl acids.

287 ) treatment, a commonly used viral clearance upstream strategy.

288 naling pathway transmits information from an upstream system to downstream systems, ideally in a unid

289 Targeting fibrinogen may be an upstream therapeutic strategy to promote the regenerativ

290 merges as a regulator of neutrophil function upstream to pyrin, is involved in NET release and regula

291 Two haplotype blocks, one upstream to the coding region of UGT2A1 (rs146712414, P

292 showed an obvious increasing trend from the upstream to the downstream in the TRB.

293 d be attractive therapeutic targets and lack upstream toxicity.

294 A-, replication-dependent histone-, promoter upstream transcript- and enhancer RNA-loci.

295 xpression as well as associated pathways and upstream transcription factors in human keratinocytes ex

296 ion module that controlled the expression of upstream transcription factors; and a phenotype module w

297 However, the upstream transcriptional regulators that mediate the fun

298 ierarchical models, here we find that higher upstream tree cover is associated with lower probability

299 3,362 children in 35 countries and find that upstream tree cover is linked to a lower probability of

300 lected variable losses of MeHg exported from upstream wetlands due to demethylation, absorption, depo