ライフサイエンスコーパス: upstream open reading frame

1 so remains operational when combined with an upstream open reading frame.

2 VAR2CSA is translationally repressed by an upstream open reading frame.

3 m of the sod start codon and to be within an upstream open reading frame.

4 ture be disrupted by translation through the upstream open reading frame.

5 e (YAP1 uORF) and two (YAP2 uORF1 and uORF2) upstream open reading frames.

6 cropeptide-encoding RNAs, and dynamic use of upstream open reading frames.

7 ntisense oligonucleotides (ASOs) that target upstream open reading frames.

8 coding sequences, including 2442 translated upstream open reading frames.

9 translated pseudogenes, non-coding RNAs and upstream open reading frames.

10 ating widespread translational regulation by upstream open reading frames.

11 sensitive to the eIF3h level by a series of upstream open reading frames.

12 Alternative initiation codons and upstream open reading frames also were identified for ma

13 ted by cis-acting RNA elements, including an upstream open reading frame and an IRES that directs syn

14 The presence of upstream open reading frame and internal ribosome entry

15 Analysis of the 5'-UTR revealed six upstream open reading frames and four inverted repeat st

16 olyribosomes due to the presence of multiple upstream open reading frames and low mRNA abundance.

17 including internal ribosome entry segments, upstream open reading frames, and microRNA target sites.

18 ive activities of its 5'-UTR, which contains upstream open reading frames, and of its 3'-UTR, which s

19 liminating the ribosome binding site for the upstream open reading frame caused an oligosporogenous p

20 s revealed that GC content and the number of upstream open reading frames could play a role in select

21 ns in its 5'-untranslated region a conserved upstream open reading frame denoted as CG42630 in FlyBas

22 naviruses, are very different, in that their upstream open reading frames encode nonstructural protei

23 Two upstream open reading frames encoding multiple aromatic

24 We reasoned that the early upstream open reading frame (EUO) gene product might pla

25 a complex 5'-untranslated region with eight upstream open reading frames, features implicated in tra

26 ndent on a splicing event that fuses a small upstream open reading frame in frame with the larger dow

27 translation of BCKD-kinase mRNA and that an upstream open reading frame in the 5'-untranslated regio

28 edicted that the insertion would convert the upstream open reading frame in the Wnt16a mRNA to an alt

29 mutations that remove or restructure a small upstream open reading frame in thrombopoietin mRNA, and

30 ZIP-2 induction is conferred by a conserved upstream open reading frame in zip-2 that could derepres

31 and identified potential regulatory RNAs and upstream open reading frames in 5'-untranslated region.

32 in normal human cells (L-mdm2) contains two upstream open reading frames in its 5' leader.

33 ingle long transcript is produced with small upstream open reading frames in its 5' untranslated regi

34 Upregulated transcripts included those with upstream open reading frames in the 5' untranslated regi

35 lves stress-induced relief of two inhibitory upstream open reading frames in the 5'-leader of the tra

36 EYA2 transcripts have dissimilar numbers of upstream open reading frames in their 5'-untranslated re

37 * 5'-UTRs and translation is modulated by an upstream open-reading frame in the unique region of the

38 Upstream open reading frames initiated by ATG but not CT

39 egion identified transcripts for malA and an upstream open reading frame located 5' to the 1-kb inter

40 indicated that ght is cotranscribed with an upstream open reading frame NMA2149.

41 st likely due to leaky scanning of the first upstream open reading frame of GCN4 mRNA.

42 l autoregulatory domain and regulation by an upstream open reading frame of Rbp35-dependent TOR signa

43 The EUO gene (for early upstream open reading frame) of Chlamydia psittaci was p

44 rios, including the repressive effect of the upstream open reading frames on gene expression and the

45 oviral and transposon RNAs, and mRNAs having upstream open reading frames or other unusual sequence f

46 when the same ribosome used to translate an upstream open reading frame (ORF) also translates a down

47 Deletion of the gene and a cotranscribed upstream open reading frame (ORF) in GBS strain 515 redu

48 The influence of an upstream open reading frame (ORF) in the 5'-untranslated

49 The presence of an upstream open reading frame (ORF) in VA-Tat RNA is inhib

50 in resting cells requires translation of an upstream open reading frame (ORF) that represses transla

51 Mt contained an unidentified, yet conserved, upstream open reading frame (ORF).

52 exon 2, which removes a portion of a small, upstream open reading frame (ORF); (ii) mice with double

53 Small upstream open reading frames (ORFs) or minicistrons loca

54 translation enhancing factor (PTEF) relieves upstream open reading frame repression and thereby facil

55 ession level of PTEF, and the alleviation of upstream open reading frame repression requires the prot

56 ndom mutation or a mutation that disrupts an upstream open reading frame, resulted in a remarkably hi

57 indicates that the mgc1 RNA starts within an upstream open reading frame, suggesting complex control

58 Many of the novel 5' UTRs include upstream open reading frames, suggesting varying transla

59 Furthermore, MeCP2beta mRNA has an upstream open reading frame that inhibits its translatio

60 sion of a transcript variant lacking a small upstream open reading frame that would otherwise inhibit

61 TR variant mutates the stop codon of a small upstream open reading frame that, using a dual-luciferas

62 leader contains two evolutionarily conserved upstream open reading frames that act together to drasti

63 (548 nucleotides) that harbors at least two upstream open reading frames that inhibit seprase-s expr

64 s cerevisiae has revealed the translation of upstream open reading frames that initiate with near-cog

65 tes defective ribosomal scanning between the upstream open reading frames that mediate translational

66 of the 3.1-kb mRNA, which encodes six small upstream open reading frames that possibly result in poo

67 This long RTC4 transcript contains small upstream open reading frames that prevent translation of

68 orting signals within primary structures and upstream open reading frames that we discovered through

69 se include the regulation of translation via upstream open reading frames, the over-reading of stop c

70 canning and initiation codon selection by 5' upstream open reading frames, translation initiation fac

71 '-leader of the mRNA, which contains a small upstream open reading frame (uORF) 14 nucleotides from t

72 An upstream open reading frame (uORF) confers the translati

73 This single small upstream open reading frame (uORF) confers translational

74 An AUG-initiated upstream open reading frame (uORF) encoding a potential

75 -2 mRNA contains an evolutionarily conserved upstream open reading frame (uORF) encoding the Arg atte

76 ccharomyces cerevisiae CPA1 mRNA contains an upstream open reading frame (uORF) encoding the arginine

77 It is encoded as an upstream open reading frame (uORF) in fungal mRNAs speci

78 ating CLN3 expression, we identified a short upstream open reading frame (uORF) in the 5' leader of C

79 The upstream open reading frame (uORF) in the 5' leader of t

80 Translation of the upstream open reading frame (uORF) in the 5' leader segm

81 on of the Lc mRNA is repressed by a 38-codon upstream open reading frame (uORF) in the 5' leader.

82 ich is controlled by a single cis-regulatory upstream open reading frame (uORF) in the 5' untranslate

83 Alternatively, downstream of a short upstream open reading frame (uORF) in the 5' untranslate

84 Translational control mediated by an upstream open reading frame (uORF) in the 5'-leader of t

85 nscripts containing mutations that insert an upstream open reading frame (uORF) in the 5'-UTR are deg

86 ts of these regulatory mechanisms is a short upstream open reading frame (uORF) in the HER-2 mRNA tha

87 Regulation of translation is dependent on an upstream open reading frame (uORF) in the INO2 leader.

88 The upstream open reading frame (uORF) in the mRNA encoding

89 The upstream open reading frame (uORF) in the mRNA encoding

90 The peptide product of an upstream open reading frame (uORF) in the mRNA is solely

91 An upstream open reading frame (uORF) in the transcript's 5

92 Members also have a conserved upstream open reading frame (uORF) in their 5' leader se

93 ion is posttranscriptionally regulated by an upstream open reading frame (uORF) located in its 5' unt

94 The Neurospora crassa arg-2 upstream open reading frame (uORF) plays a role in negat

95 alpha and the translation of a 48-amino acid upstream open reading frame (uORF) present within the 5'

96 ach AUG codon and on the presence of a short upstream open reading frame (uORF) resulting in the mito

97 urospora crassa arg-2 transcript contains an upstream open reading frame (uORF) specifying a 24-resid

98 The long 5' UTR of GRN mRNA contains an upstream open reading frame (uORF) that is absent in all

99 We previously described an upstream open reading frame (uORF) that is responsible f

100 r region of most R genes contains a 38-codon upstream open reading frame (uORF) that previously was s

101 This regulation requires a cis-acting upstream open reading frame (uORF) that represses the tr

102 possess at least one efficiently translated upstream open reading frame (uORF) that represses transl

103 ctivity requires both translation of a small upstream open reading frame (uORF) within the IRES and p

104 cis-acting sequences is contained within an upstream open reading frame (uORF), and its activity see

105 al cell lines by an evolutionarily conserved upstream open reading frame (uORF), which acts in cis to

106 mal reinitiation following translation of an upstream open reading frame (uORF).

107 tor peptide (AAP) is encoded by a regulatory upstream open reading frame (uORF).

108 stream initiations, contain an out-of-frame, upstream open reading frame (uORF).

109 hin the different isoforms and by inhibitory upstream Open Reading Frames (uORF) in their 5' UTRs.

110 gna-2 mRNA has two upstream open reading frames (uORF), resulting in two pr

111 -like transcription factor Yap2 contains two upstream open reading frames (uORF1 and uORF2).

112 (CMV) gpUL4 (gp48) gene contains a 22-codon upstream open reading frame (uORF2) that represses trans

113 ressed at the translational level by a short upstream open reading frame (uORF2) within the UL4 trans

114 ovirus (HCMV) gpUL4 mRNA contains a 22-codon upstream open reading frame (uORF2), the peptide product

115 ne is inhibited by translation of a 22-codon-upstream open reading frame (uORF2).

116 NAs harboring premature stop-codons or short upstream open reading frame (uORFs).

117 translation initiation codon (AUG)-initiated upstream open reading frames (uORFs) (nAuORFs 1 and 2) o

118 tionally characterize a complex landscape of upstream open reading frames (uORFs) across 5'-untransla

119 analysis of the translation and function of upstream open reading frames (uORFs) across vertebrates.

120 exin II receptor (AXIIR) mRNA, there are two upstream open reading frames (uORFs) acting in a fail-sa

121 cerevisiae GCN4 mRNA 5'-leader contains four upstream open reading frames (uORFs) and the CPA1 leader

122 L-mdm2 mRNA contains two upstream open reading frames (uORFs) and this mRNA was l

123 Upstream open reading frames (uORFs) are elements found

124 ootprint profiling, that actively translated upstream open reading frames (uORFs) are enriched in tra

125 Upstream open reading frames (uORFs) are frequently pres

126 Upstream open reading frames (uORFs) are known to regula

127 Transcripts harboring 5' upstream open reading frames (uORFs) are often found in

128 Upstream open reading frames (uORFs) are ubiquitous repr

129 Excision of a 405 bp region containing three upstream open reading frames (uORFs) from the 5'-UTR dra

130 nscript has been reported to be regulated by upstream open reading frames (uORFs) in a manner of re-i

131 n41 mRNA is strongly controlled by the three upstream open reading frames (uORFs) in its 5' untransla

132 tive to the Mrp2 ATG) and contains potential upstream open reading frames (uORFs) in the 5' untransla

133 egulated at the translational level by short upstream open reading frames (uORFs) In the 5'-untransla

134 ns, and this effect requires the presence of upstream open reading frames (uORFs) in the 5'-untransla

135 For example, inclusion or exclusion of upstream open reading frames (uORFs) in the 5'UTR as wel

136 f AU-rich elements (AREs) in their 3'UTR and upstream open reading frames (uORFs) in their 5 UTR than

137 own of the mechanisms through which multiple upstream open reading frames (uORFs) interact to regulat

138 mRNA via a unique mechanism involving short upstream open reading frames (uORFs) located in the 5' u

139 ATF5 translational control involves two upstream open reading frames (uORFs) located in the 5'-l

140 By examining conserved peptide upstream open reading frames (uORFs) of Arabidopsis and

141 ne produces an mRNA that contains four short upstream open reading frames (uORFs) preceding the GCN4

142 This includes upstream open reading frames (uORFs) present in mRNAs co

143 modified ASOs that bind to mRNA sequences in upstream open reading frames (uORFs) to specifically inc

144 ntrolled by ribosome interactions with short upstream open reading frames (uORFs) within the 5'untran

145 in expression of Kozak sequence composition, upstream open reading frames (uORFs), and secondary stru

146 ng on nonsense-mediated decay (NMD) targets, upstream open reading frames (uORFs), canonical ORFs sho

147 Upstream open reading frames (uORFs), located in transcr

148 , and viral transcript leaders contain short upstream open reading frames (uORFs), yet the significan

149 lternatively spliced introns and up to three upstream open reading frames (uORFs).

150 5' regions of eukaryotic mRNAs often contain upstream open reading frames (uORFs).

151 contains seven upstream start codons and six upstream open reading frames (uORFs).

152 transcriptional activator GCN4 controlled by upstream open reading frames (uORFs).

153 UTR) that holds six AUGs, leading to several upstream open reading frames (uORFs).

154 ranslated region of 1.3 kb that contains two upstream open-reading frames (uORFs).

155 In many eukaryotic mRNAs one or more short 'upstream' open reading frames, uORFs, precede the initia

156 le promoter but also two pathogen-responsive upstream open reading frames (uORFsTBF1) of the TBF1 gen

157 pends in part on the size and arrangement of upstream open reading frames (upORFs).

158 reased hemA expression in the absence of the upstream open reading frame, we isolated three independe

159 onounced effect resulted from mutation of an upstream open reading frame, which restored translationa

160 mino-terminal extensions and truncations and upstream open reading frames with regulatory potential,