ライフサイエンスコーパス: upstream region

1 he BCL6 promoter interacts with this distant upstream region.

2 ms (-2022C/T and -1592G/C) within the repeat upstream region.

3 x compete for a target sequence in the Epha4 upstream region.

4 reas around exons, most frequently in the 5' upstream region.

5 lement(s) within the approximately 1.4-kb 5'-upstream region.

6 ssion by isolating and characterizing its 5' upstream region.

7 rather than by regulatory elements in the 5' upstream region.

8 in mice from which we deleted this conserved upstream region.

9 ontaining a 1.5 kb fragment of the mGSTA3 5'-upstream region.

10 t-specific suppressor activity in the distal upstream region.

11 nd one sigma(28) site were found in the flgM upstream region.

12 located at position -116 within the proximal upstream region.

13 abrogated binding of OmpR:6xHis to the tviA upstream region.

14 ene and one such target site in the act gene upstream region.

15 m-a induced KRT3 expression by targeting its upstream region.

16 by binding an inverted repeat element in its upstream region.

17 ween the RepR binding sites in tcdR and repR upstream regions.

18 were also present in the Arabidopsis CBF1-3 upstream regions.

19 5'-UTRs, introns, coding exons, 3'-UTRs, and upstream regions.

20 l layers of medial entorhinal cortex and its upstream regions.

21 does not require an alignment of orthologous upstream regions.

22 in addition to inheriting activity from the upstream regions.

23 f heptad TTTTGAT repeats in their respective upstream regions.

24 lower in the transcribed regions than in the upstream regions.

25 (particularly Alu elements) present in these upstream regions.

26 cific parts of the basal promoter or further upstream regions.

27 nd RPGR (including ORF15) genes and their 5' upstream regions.

28 possible DNA bending, particularly at operon-upstream regions.

29 ring revealed 78 genes in which the promoter/upstream region (-10 kb to +0.5 kb) was recognized by ST

30 previously demonstrated that the human BEST1 upstream region -154 to +38 bp is sufficient to direct e

31 ns of DNA proximal to the ilvIH promoter, an upstream region (-260 to -190) and a downstream region (

32 n coding sequences, 37 in introns, and 12 in upstream regions; 3 of 4 rare novel coding SNPs were non

33 quences (PQSS), which occur in the immediate upstream region (500 bp) of human genes.

34 merase molecules at the fis promoter and the upstream region acts as a topological device regulating

35 ain a highly conserved hexanucleotide in the upstream region and a far less conserved U/GU-rich seque

36 in a head-to-head orientation share the same upstream region and are likely to be coregulated.

37 e that integration host factor binds to this upstream region and increases in vivo expression of Pfnr

38 tions occurred within the hTERT promoter and upstream region and the fifth integration occurred in in

39 oriD; second, the PcrA is recruited to this upstream region and thirdly upon ATP-binding PcrA reloca

40 We here screen this upstream region and uncover multiple enhancers that acti

41 pmental regulation of pknE required a 118-bp upstream region and was abolished in a hetR mutant.

42 at pH 7 was able to interact with the bba66 upstream region and was specific as bba64 and ospC promo

43 hese extended 3'-end regions than within PAS-upstream regions and indeed are substantially more folde

44 num CBF1 upstream regions over the other CBF upstream regions and that CBF4 has retained the capacity

45 marks at the Peg13 and Slc38a4 DMRs, Cdkn1c upstream region, and Inpp5f_v2 DMR and paternal allele-s

46 x10 was also found to be associated with the upstream region, and its binding was required for Egr2-m

47 compared the sequence organization of their upstream regions, and examined their allelic methylation

48 ical tandem repeats (49-61 bp) in the hRFC-A upstream region are involved in regulating promoter acti

49 lthough the clustered AUUUA pentamers in the upstream region are required for stimulus sensitivity, m

50 Many overrepresented motifs in C. parvum upstream regions are not AP2 binding motifs.

51 h degrees of variability of their respective upstream regions are preferentially involved in environm

52 The upstream regions are well conserved, especially the pres

53 on near the phosphorylation site but not the upstream region around Cys(595), away from F-actin, thus

54 that encompassed the SUC2 gene promoter and upstream region but was devoid of other transcriptionall

55 on of PhyC, but frequent interruption of the upstream regions by the insertion of retroelements and o

56 rucial for basal transcription, and that two upstream regions can act as positive or negative regulat

57 ging this haplotype, located in the ZNRD1 5' upstream region, caused a loss of nuclear factor binding

58 th the pseudo-SNP allele frequency and GSTM1 upstream region CNV show population-specific patterns be

59 ences in CRT/DRE copy numbers in CAS30/CAS31 upstream regions combined with differences in gene copy

60 sequences and pools of coding and non-coding upstream regions, compare the observed symmetry levels t

61 The upstream regions contain common and unique segments.

62 This upstream region contained five direct repeats of 59 base

63 er approach, in which a portion of the dHAND upstream region containing an enhancer that directs dHAN

64 ns a helix-turn-helix motif, while the ORF16 upstream region contains attributes of a theta-replicati

65 We hypothesized that the murine c-myb upstream region contains regulatory elements accessed by

66 hat although the ATTARA sequence in the Psag upstream region contains thymine residues important for

67 ocampus receives gamma frequency inputs from upstream regions (cornu ammonis area 3 and medial entorh

68 methylated) cells in a previously unexplored upstream region, correlating with a 2.7-fold difference

69 ed histone levels increased, particularly at upstream regions, correlating with a 2-fold increase in

70 Similarly, deletion analyses of the recA upstream region defined sequences required for gene vari

71 r rs366631 genotype is an indicator of GSTM1 upstream region deletion.

72 '- and 3'-untranslated region, and immediate upstream region did not reveal the underlying mutation.

73 vivo, the ankyrin erythroid promoter and its upstream region direct position-independent, uniform exp

74 the DRR into two segments, a 376 nucleotide upstream region (DRR(-2473/-2100)) and a 147 nucleotide

75 Genes with upstream regions enriched for SINEs are prone to be reac

76 chip data indicate that FLP/MYB88 target the upstream regions especially of cell cycle genes, includi

77 We demonstrated that the upstream region extending from -1647 to -10 bp or from -

78 The human BEST1 upstream region from -154 to +38 bp is sufficient to dir

79 Previously, we defined the VMD2 upstream region from -253 to +38 bp as being sufficient

80 cC protects about 25 nucleotides of the P(F) upstream region from DNase I digestion, and RNA polymera

81 Here we show that 2 kilobases of 5' upstream region from the mouse keratin 17 gene (mK17) co

82 informative pedigrees, and sequencing SHARP1 upstream regions from normal and affected dogs will be n

83 we explored the function of the 3.7-kb Gata1 upstream region (GdC region) that harbors 3 core cis-ele

84 valuated a 5' distal weak enhancer (IGF-1 5'-upstream region growth hormone response element; 5URGHRE

85 Previously, we showed that the G564 upstream region has a block of tandem repeats, which con

86 s of the wheat PhyC gene and of some 5 kb of upstream region has demonstrated a high level of conserv

87 cumbens integrates information from multiple upstream regions has been a central question for decades

88 generator is independent of activity in the upstream regions, highlighting that CA1 can produce its

89 is a large secreted glycoprotein composed of upstream regions I-II-III, followed by the approximately

90 ments and acetylation of expressed immediate upstream regions implicates involvement of epigenetic me

91 ns of tcdR in C. difficile PaLoc and in repR upstream region in PhiCD119 by gel shift assays.

92 Deletion of a 395 bp upstream region in the MOR23 minigene abolishes expressi

93 patients had abnormal imprinting of the more upstream regions in addition to the exon 1A imprinting d

94 med in telomere reverse transcriptase (TERT) upstream regions in several cancers, associated with ele

95 promoters, despite being able to bind their upstream regions in vitro.

96 We comprehensively screened the 5' upstream region (including the predicted promoter), all

97 nsulator allows the enhancers to contact the upstream regions, including Igf2.

98 pletely abolishes TCR in both the coding and upstream regions, indicating that no other TCR subpathwa

99 Cloning of this upstream region into a green-fluorescent protein (GFP) r

100 tity in the photosystem II protein D1 (psbA) upstream region is 59% across all taxa; similar variatio

101 The upstream region is comparably stabilized in response to

102 in configuration of Crabp1 promoter with its upstream region is maintained, but the 6-nucleosomes spa

103 The upstream region is organized into a positioned nucleosom

104 we showed that a 54-bp fragment of the G564 upstream region is sufficient for suspensor transcriptio

105 In the upstream region it binds to five AT-rich sites of which

106 ted with a portion of the NFAT1 gene and its upstream region, leading to the repression of NFAT1 expr

107 iation in the 5' end of TGFbeta1 or a nearby upstream region modifies disease severity in cystic fibr

108 ed extended promoter regions with regulatory upstream regions more than 1,000 bp from the transcripti

109 hat the most conserved 8-mer sequence in the upstream region of 21U-RNAs, CTGTTTCA, is absolutely req

110 , BME3, had a T-DNA insertion site in the 5' upstream region of a GATA-type zinc finger transcription

111 information of multiple binding sites in the upstream region of a gene and that in the upstream regio

112 nonnucleosomal histone-DNA particles in the upstream region of active promoters in vivo.

113 tion showed that the affinity of Lrp for the upstream region of all of these constructs was about the

114 detected in a fragment of 4,700 bp of the 5' upstream region of all self-compatible samples of the S

115 ve promoter site (amyP2), which overlaps the upstream region of amyP, were eliminated by mutagenesis

116 In particular, the 5' upstream region of BCL-2 contains a number of elements t

117 10(-15)), PRIC285 (P = 3.0 x 10(-10)) and an upstream region of CDKN1A (P = 2 x 10(-52)), suggesting

118 ion factor binding site (TFBS) motifs in the upstream region of coexpressed genes is therefore critic

119 high affinity for ComE as that seen with the upstream region of comC.

120 identified by mutational analysis of the 5' upstream region of CTR1.

121 These results demonstrated that the 5'-upstream region of CYP3A4 contains an active putative do

122 deletion was detected at locus 74k in the 5' upstream region of DMBT1, and four tightly linked polymo

123 FrtR bound to the upstream region of frtA, but binding was not visibly alt

124 onsive element (FeRE) that is present in the upstream region of genes in the iron regulon.

125 cription factors are over-represented in the upstream region of genes regulated during consolidation

126 siae to predict cis-regulatory motifs in the upstream region of genes.

127 tion to show that Fur bound, in vivo, to the upstream region of hns in a metal-dependent fashion.

128 ve promoters are localized within the 200-kb upstream region of human and mouse PEG3, which is well c

129 In silico analysis of 5'-upstream region of human MDR3 gene revealed a number of

130 Nonetheless, a 5.8 kb upstream region of human QRX is capable of directing exp

131 at MrpC binds to at least eight sites in the upstream region of its promoter.

132 ealed that a 54-bp insertion mutation in the upstream region of miR-15a-16 displayed high allele freq

133 region of miR-184, and the CpG sites at the upstream region of miR-184 were hypermethylated.

134 rtion or deletion of genetic elements at the upstream region of opcA.

135 The upstream region of orf2c contained two inverted-repeat h

136 Moreover, the upstream region of OsBZ8 gene has highly dynamic nucleos

137 8, 180, and 184 in helix 3 might contact the upstream region of P(E).

138 sults indicate that activator binding to the upstream region of P2 late promoters compensates in part

139 ranscription factors CREB and AP1 within the upstream region of P41 that are absent from the AAV2 cap

140 and point mutations were introduced into the upstream region of pnrfA demonstrated that an additional

141 oson-derived 24-nt RNAs target and cover the upstream region of retained genes preferentially when lo

142 Analysis of the upstream region of rivR identified a novel promoter the

143 acZ reporter gene was controlled by the 3-kb upstream region of RPGR.

144 nstrated that regulatory sequences in the 5' upstream region of Rpx are important for early expressio

145 bind two LIM protein-binding sites in the 5' upstream region of Rpx, which are required for Rpx promo

146 Ryp1 associates with the upstream region of RYP2, and each of the three RYP genes

147 "chimeraR16-rev," in which sR16 and a small upstream region of RyR1 were replaced by RyR2 sequence.

148 nteraction of the sarT gene product with the upstream region of sarS is likely direct.

149 nscription factor NtcA binds to sites in the upstream region of sigE and that this binding is enhance

150 Variants spanning the upstream region of SIM1 through intron 8 were associated

151 conserved noncoding sequences within the 5' upstream region of STM genes in both simple and compound

152 The presence of GATA-like motifs in the upstream region of the Acl1.4 gene (encoding for ACP4) a

153 leotide substitutions have been found in the upstream region of the ankyrin gene promoter that is act

154 These data indicate that an upstream region of the ankyrin-1 erythroid promoter acts

155 e show that GATA-1 binds a highly restricted upstream region of the approximately 70-kb GATA-2 domain

156 A 1.41 kb fragment from the 5' upstream region of the AtFC-II gene was fused to the luc

157 Analysis of the upstream region of the AtGPX genes revealed the presence

158 We have carried out a mutational scan of the upstream region of the bacteriophage P2 FETUD late opero

159 The 5' upstream region of the beta1 sGC gene was isolated and a

160 umber of normally methylated CpGs in the far-upstream region of the boundary is decreased about 4-fol

161 In this study, we have characterized the upstream region of the CD1D1 gene and identified a minim

162 An upstream region of the cers2b promoter supports enhanced

163 The function of the upstream region of the chicken betaB1-crystallin promote

164 on of USF transcriptional activity in the 5' upstream region of the COX-2 gene.

165 known cis-elements were identified in the 5'-upstream region of the CYP2F1 promoter.

166 E-box repressor motif, not present in the 5'-upstream region of the CYP3A5 gene, that attenuates CYP3

167 HIF-1, AP-1, and NFAT are located within the upstream region of the cytoglobin gene.

168 The variability in the upstream region of the D-loop revealed additional differ

169 nctional polymorphism (-1021C-->T) in the 5' upstream region of the DBH gene that accounted for 35%-5

170 ct and specific interaction of MisR with the upstream region of the dsbD promoter was demonstrated by

171 previously that GATA-1 replaces GATA-2 at an upstream region of the GATA-2 locus, and that this GATA

172 ake up the original risk haplotype in the 5' upstream region of the gene for their effects on mRNA ab

173 cribed from the same gene locus, the 2320 bp upstream region of the gene was functionally characteriz

174 to the cis-regulatory motif structure in the upstream region of the gene, multiple trans-acting facto

175 g sites and other regulatory elements in the upstream region of the genes, as contained in the Saccha

176 le specific information exists about the far-upstream region of the hiNOS gene.

177 a is complementary to the sequence in the 5' upstream region of the IL-1beta promoter.

178 557_66,024,773del) located at the non-coding upstream region of the KLC2 gene.

179 he lysine-sensitive factor that binds to the upstream region of the Klebsiella pneumoniae gdhA promot

180 One SNP, in the immediate upstream region of the LpHD1 coding sequence (C-4443-A),

181 to bind to a CRP binding site located in the upstream region of the lsr promoter and works with the L

182 siRNA loci were specifically enriched in the upstream region of the most highly expressed genes.

183 hrough deletion analysis of a -907/+70-bp 5' upstream region of the mouse COX-2 gene, we identified a

184 ChIP scan of the 6-kb 5' upstream region of the mouse nephrin gene identified sev

185 SOX9 bound a conserved upstream region of the OPN gene, and abrogation of Sox9

186 The upstream region of the Pantoea stewartii rcsA gene featu

187 asmids that incorporate up to 2.86 kb of the upstream region of the rat follistatin gene are not indu

188 We hypothesize that DsrABb binds to the upstream region of the rpoS mRNA and stimulates translat

189 an essential requirement for binding to the upstream region of the rtxA1 operon and is the key featu

190 nally orthologous nucleotide variants in the upstream region of the same gene, WntA, are responsible

191 Purified MgrA protein bound to the upstream region of the sarX promoter as demonstrated by

192 We analyzed the upstream region of the scarlet runner bean (Phaseolus co

193 We analyzed the upstream region of the Scarlet Runner Bean (Phaseolus co

194 Genetic polymorphisms in the repeat upstream region of the serotonin transporter gene (SLC6A

195 independent chromosomal rearrangement in the upstream region of the streptolysin O (slo) gene of Stre

196 Focusing on sigma(E), we discovered that the upstream region of the T2S operon possesses both the con

197 is facilitated by reannealing of DNA in the upstream region of the transcription bubble, as is also

198 We identified and compared the upstream region of the transcription start sites of each

199 The 5'-upstream region of this endo-beta-mannanase gene contain

200 potential to extensively base-pair with the upstream region of this rpoS transcript.

201 that both Sox2 and TLX proteins bind to the upstream region of Tlx gene.

202 case-control study design, we show that the upstream region of TNFSF4 contains a single risk haploty

203 commonly occurring sequence motifs in the 5' upstream region of transcripts for subset of down-regula

204 1 elements by promoting integration into the upstream region of tRNA genes.

205 gMyb2 binding sites were not found in the upstream regions of 31 other giardial genes.

206 The upstream regions of 54% of the predicted pri-miRNAs are

207 ys identified NF-kappaB binding sites in the upstream regions of 75% of the genes regulated by GSK-3.

208 The upstream regions of all genes in the four groups were sc

209 n receptor, through a systematic analysis of upstream regions of all human and mouse genes.

210 nscription factor binding site motifs in the upstream regions of all S. cerevisiae genes and the gene

211 tified an 18 bp inverted repeat motif in six upstream regions of all seven operons directly regulated

212 Deletions of the upstream regions of both genes indicated that 324 bp of

213 sence of distinct regulatory elements in the upstream regions of both genes.

214 ulator MprA bound to conserved motifs in the upstream regions of both sigB and sigE in vitro and regu

215 identified as a common sequence motif in the upstream regions of calcineurin/ Crz1p-dependent genes.

216 of the cotH in Bacillus subtilis, as well as upstream regions of certain genes, such as the sucC gene

217 ay-based studies have successfully mined the upstream regions of co-expressed genes and discovered ov

218 ification of common regulatory motifs in the upstream regions of co-regulated genes.

219 ed transcription factor binding sites in the upstream regions of either single or grouped eukaryotic

220 rison of the CTnDOT tetQ leader regions with upstream regions of five tetQ genes found in other eleme

221 equence similarity metric operating on 10 kb upstream regions of gene pairs quantitatively predicts a

222 We analyzed upstream regions of genes associated with NAD biosynthes

223 to identify cis-regulatory binding sites in upstream regions of genes co-regulated in embryonic stem

224 frequent occurrence of telobox motifs in the upstream regions of genes in this category, but it is no

225 mputation can be used to search for TFBSs in upstream regions of genes known to be coexpressed.

226 sequences using the PWM and map SNPs to the upstream regions of genes; (iii) examine the evolutionar

227 ed marked variations in H3K9Ac levels at the upstream regions of HLA-DRB1 and HLA-DQB1 within the ins

228 he upstream region of a gene and that in the upstream regions of its orthologues in related genomes.

229 Analysis of the upstream regions of Kar4-induced genes identified a DNA

230 rames (ORFs) on unannnotated transcripts and upstream regions of known transcripts (uORFs).

231 se I footprint analysis was performed on the upstream regions of norB and nsrR, where NsrR was shown

232 CcpA bound to the upstream regions of rocF and rocD but not to that of pro

233 DNA-binding assays revealed BadR binds to upstream regions of rpoS.

234 reveals that target sites are present in the upstream regions of several cardiac-expressed genes incl

235 sites can be recognized in the promoter and upstream regions of several OR genes.

236 rter strains containing gfp fusions with the upstream regions of sigB2, sigD, sigI, and sigJ did not

237 Here, we show that the proximal upstream regions of six visual cycle genes contain chrom

238 ix-His tag and documented its binding to the upstream regions of tcdR in C. difficile PaLoc and in re

239 with computer-based pattern searches of the upstream regions of the 26 other Sig1 regulon members, t

240 of NF-kappaB consensus binding sites in the upstream regions of the 43 coexpressed genes.

241 Upstream regions of the 5' exon and the entire 3' exon,

242 2 GC/GT-box elements (GC-f and GT-d) in the upstream regions of the CBS -1b promoter in CMK nuclear

243 nd transgenic mice were used to characterize upstream regions of the chicken betaB1-crystallin gene.

244 Sequence analysis of the upstream regions of the complete regulon identified a 15

245 from the expanded GAA-TR in intron 1 to the upstream regions of the FXN gene, involving the FXN tran

246 We have cloned the 5' upstream regions of the genes encoding the two isoflavon

247 The upstream regions of the genes lack a conventional TATA b

248 ndromic sequence (5'-GGAA-N6-TTCC-3') in the upstream regions of the idhA, iolY, iolR, and iolC genes

249 fied a common sequence motif enriched in the upstream regions of the most consistently cytokinin up-r

250 5)GFI(217) anchors these potentially dynamic upstream regions of the protein to maintain protein inte

251 By comparing the upstream regions of the vertebrate vRNA genes, a 25 bp c

252 We analyzed the upstream regions of these genes using computational DNA

253 ucleosomes are enriched on the coding and/or upstream regions of these genes, suggesting that their i

254 for CREB were highly over-represented in the upstream regions of these genes, with 9 genes containing

255 Ty1, 2, and 4 elements also cluster in the upstream regions of these genes.

256 In the upstream regions of these mitochondrial dysfunction stim

257 The upstream regions of these operons contain no PpsR bindin

258 Nrf2 binds directly to upstream regions of these pluripotency genes to promote

259 andidate mechanism of neuroplasticity within upstream regions of this inhibitory network after chroni

260 position of endogenous Ty1 elements into the upstream regions of tRNA(Gly) genes was substantially de

261 The expression of lacZ fusions to the upstream regions of two B. anthracis extracellular prote

262 Intriguingly, this region encompasses the upstream regions of two divergently transcribed genes an

263 High-affinity sites develop only in upstream regions of VWF where tension exceeds 21 pN and

264 constraints are placed upon the Solanum CBF1 upstream regions over the other CBF upstream regions and

265 vR bound to two extended regions of Psag, an upstream region overlapping the -35 and -10 promoter ele

266 ion and site-directed mutagenesis of the dCK upstream region (positions -464 to -27) confirmed the im

267 Several alleles differing in the 5'-upstream region (promoter) of this gene were identified,

268 d spatial expression, we constructed a -5 kb upstream region rat DSP-PP promoter into the beta-galact

269 that determine how the ribosome binds these upstream regions remain poorly defined.

270 Nevertheless, the CBF1 upstream region remains intact and highly conserved.

271 Analysis of HuR upstream regions revealed sequences necessary for regula

272 sitive sites at the TERT promoters and their upstream regions, revealing positions of potential regul

273 d up to 600 kb downstream of Y1, whereas the upstream region showed a more rapid recovery.

274 single allele (-13910( *)T, rs4988235) in an upstream region that acts as an enhancer to the expressi

275 and SOX10-we found several enhancers in this upstream region that contain open chromatin and direct r

276 The SP6 tail gene is flanked by an upstream region that contains a promoter and a downstrea

277 tion to juxtaposition of HPFH enhancers, the upstream region that is absent in the beta-YAC construct

278 These occur in an upstream region that is marked by an osmotic shock promo

279 e structural viral Gag protein with an extra upstream region that provides a cytosolic domain and a p

280 error, rather than inherit it passively from upstream regions; that they combine multiple separate an

281 H2 (FR-H2) possessing CRT/DRE sites in their upstream regions, the most notable of which was CBF12.

282 EGF-D, in which incorporation is confined to upstream regions, the presence of exogenous H3 results i

283 box consensus sequence in the rabbit Aldh1a1 upstream region; these elements are prevalent in other h

284 Within the 81-bp upstream region, three Sp transcription factor binding s

285 d a strong candidate Fur-binding site in its upstream region, thus suggesting that omcA may be a dire

286 vity and showed the ability of GerB and GerF upstream regions to drive gfp expression in coleoptiles,

287 otide composition between coding regions and upstream regions to rank putative open reading frames ba

288 reened for deletion/duplication of the PITX2 upstream region using arrays and probes.

289 tches, and apply it to the pooled 500 bp ORF Upstream Regions (USRs) of yeast.

290 ighly conserved among the LEEs, although the upstream regions varied considerably for tir and the cru

291 In Nonabokra, the upstream region was hyperacetylated at H3K9 and H3K27, a

292 is of single nucleotide polymorphisms in the upstream region was used to determine the extent of the

293 CcpA's binding to the upstream regions was greatly enhanced by phosphorylated

294 dentify regulatory sites in the murine c-myb upstream region, we looked by chromatin immunoprecipitat

295 cesses were impaired when the YSS and/or its upstream region were incomplete or altered.

296 is feature differed for CBF2 and CBF3, whose upstream regions were far less conserved.

297 ifs shared between the Solanum CBF1 and CBF4 upstream regions were identified, portions of which were

298 motifs, the cognate CBF binding site in its upstream region whereas MtCAS31 lacked one CRT/DRE partn

299 edicted operators in the norB, aniA and nsrR upstream regions with a K(d) of 7, 19 and 35 nM respecti

300 te gene structure of the human AGRP gene and upstream regions with differential promoter activity.