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1 trolled thermal pyrolysis of citric acid and urea.
2 ingolipids, biogenic amines, amino acids and urea.
3 mitochondrial cyclophilin (CPR3) induced by urea.
4 spontaneous unfolding and refolding in zero urea.
5 transistors (rGO FETs) for the detection of urea.
6 ate as a function of force, temperature, and urea.
7 ing from washing a crude preparation with 9M urea.
8 nt is found to be favored in the presence of urea.
9 e, dichromate, salicylic acid, melamine, and urea.
10 he denaturants guanidinium hydrochloride and urea.
11 d paracellular flux of sodium, chloride, and urea.
12 l pH produced by the catalyzed hydrolysis of urea.
13 ogel in response to the external stimulus of urea.
14 into the corresponding amine, carbamate, and urea.
15 tated the permeation of water, glycerol, and urea.
16 f each domain by equilibrium denaturation in urea.
17 as not affected by H-bond destabilization by urea.
18 cts of another naturally occurring osmolyte, urea.
19 3,5-bis(trifluoromethyl)phenyl and boronate ureas.
20 Similarly, for glucose (0-400 mg/dL) and urea (0-250 mg/dL) spiked samples, relative RMSECVs were
21 %) was GFR = 45.9 x (creatinine(-0.836) ) x (urea(-0.229) ) x (international normalized ratio(-0.113)
22 lism pathway, a positive correlation between urea-1-carboxylate and AHR was observed in plasma metabo
23 to the identification of isoquinoline ethyl urea 13 as a promising starting point for fragment evolu
27 e interfacial liquid viscosity indicate that urea accumulates extensively near the silica surface, wh
28 polyunsaturated fatty acids by formation of urea adducts from three different sources was studied to
31 ed include nitrate, nitrite, ammonium salts, urea, amino acids, sugars, organic acids, amides, triazi
32 number of these compounds, particularly the urea analogues, were quite potent, these molecules as a
33 e simultaneous quantification of glucose and urea analytes along with malaria parasitemia quantificat
34 n mouse models and determined that increased urea and a corresponding increase in urea transporters i
36 mide and hydrocarbon moieties and effects of urea and alkylureas on aqueous processes to be predicted
38 re lysed in SDS, which is then exchanged for urea and ammonium bicarbonate in a centrifugal filter, b
40 osarcina pasteurii, and pulsed injections of urea and calcium substrate, the NMR measured water conte
41 status (>/=7 days) was estimated using serum urea and creatinine levels of 1,448 samples collected fr
42 rectomy resulted in significant increases in urea and creatinine levels, a small (P<0.05) reduction i
43 oanthocyanidins reduced gluten solubility in urea and decreased surface hydrophobicity of glutenins,
44 on states can be determined from analysis of urea and diethylurea effects on equilibrium and rate con
45 ring the effect of two biological osmolytes, urea and glycerol, on the surface charge of silica, an a
46 lar simulations to investigate the effect of urea and guanidinium chloride on the structure of the in
54 hese data yields strengths of interaction of ureas and naphthalene with amide sp(2)O, amide sp(2)N, a
59 we quantify interactions of urea, alkylated ureas, and other amides by osmometry and amide-aromatic
61 agnitude, the reactivities of several diaryl urea anions correlated to the electron-withdrawing subst
63 mulative NH3 loss in the two weeks following urea application without Limus ranged from 9-108 kg N ha
65 ry efficiency (REN) and N balance when using urea applied with or without Limus were also measured ov
67 s crucial; this study explores the nature of urea-aromatic interactions relevant in urea-assisted pro
68 ond-long unrestrained simulations shows that urea-aromatic stacking interactions are stabilizing and
69 inally, we validate the ubiquitous nature of urea-aromatic stacking interactions by analyzing experim
70 s involving fragments of the anion receptor (urea, aryl ring, etc.) are predicted to produce an inver
75 e miniprotein in the presence and absence of urea at three different temperatures demonstrate the dis
77 e to lactate flux (kPL ) and urea perfusion (urea AUC) that correlated with TRAMP tumor histologic gr
78 queous optical clearing agent, termed UbasM: Urea-Based Amino-Sugar Mixture, that rapidly renders fix
79 ized receptor with the unique combination of urea-based cleft and thiourea-based cleft in a single re
81 functional tripodal receptor that contains a urea-based inner cleft and a thiourea-based outer cleft,
84 idinone) (THP) chelator with the established urea-based PSMA inhibitor was synthesized and radiolabel
86 e, with its luminescence being quenched upon urea being enzymatically converted into ammonia and carb
88 ns of parameters like total leucocyte count, urea, bilirubin, alanine transaminase, aspartate transam
90 nd-mediated signalling mechanism between the urea binding site on the indicator cross-linker and the
91 ensor and 112 +/- 3.36 mAM(-1)cm(-2) for the urea biosensor, with apparent Michaelis-Menten constants
93 ectrode (ISE) membranes with tren-based tris-urea bis(CF3) tripodal compound (ionophore I) were found
94 hosteric, contacting the helical bundle) and urea BPTU (allosteric, on the external receptor surface)
97 MAO can counteract the denaturing effects of urea by inhibiting protein-urea preferential interaction
99 s (KM,app), obtained from the creatinine and urea calibration curves, of 0.163 mM for creatinine deam
100 We have previously reported that triazole ureas can act as selective and CNS-active inhibitors for
101 carbonylative C-C activation of cyclopropyl ureas can be "captured" by pendant nucleophiles prior to
103 works for cinchonidine or cinchona alkaloid-urea catalyzed sulfa-Michael addition reactions, also ap
107 ion for renal function (serum creatinine and urea), complement deposition (C3b/c and C9), and infiltr
115 d MIOX-TG mice had even greater increases in urea, creatinine, and KIM-1 levels and more tubular inju
118 demonstrates enhanced nitrogen flux into the urea cycle and infusion of (15)N-arginine shows that Arg
119 ses in sphingolipids, indicate that both the urea cycle and nitric oxide pathways are dysregulated at
121 d ammonia levels due to dysregulation of the urea cycle are known to cause neurologic impairment.
123 ewborn mice with a partial deficiency in the urea cycle disorder enzyme, ornithine transcarbamylase (
126 metabolites remain unchanged from rest; but urea cycle intermediates are increased, likely attributa
128 ficantly associated with decreased levels of urea cycle metabolites and increased plasma glycine leve
129 FXR-knockout mice had reduced expression of urea cycle proteins, and accumulated precursors of ureag
130 d H2/CO2 (compared to fructose) point to the urea cycle, uptake and degradation of peptides and amino
133 ified by hepatic GS and approximately 35% by urea-cycle enzymes, while approximately 30% is not clear
141 weak correlations between oxidation rates of urea-derived N and the abundance or transcription of put
143 s were always higher than oxidation rates of urea-derived N in samples from coastal Georgia, USA (mea
146 Low concentrations of the chaotropic agent urea do not affect native Env but destabilize perturbed
147 he corresponding starting E- or Z-N'-alkenyl urea, each of which may be formed from the same N-allyl
150 S/ACN/urea was used, compared to the 30% ACN/urea extraction, indicating the role of SDS to be benefi
151 erturbants commonly used to unfold proteins (urea, force, and temperature) affect the denatured-state
153 achieved for the synthesis of indole-cyclic urea fused derivatives through a double cyclization proc
154 Here we report that the deprotonation of ureas generates a class of versatile catalysts that are
155 s-linker (containing a 1,3-bis-(4-oxo-butyl)-urea group, BuUrBu) generating characteristic doublet pa
156 e synthesized in one step using formic acid, urea, guanidine carbonate, and phenylisocyanate, respect
158 ssable azobenzene tether functionalized with urea hydrogen-bonding groups and d-carbohydrates as chir
159 er every urination event was able to inhibit urea hydrolysis in synthetic urine and real urine as ind
160 to provide an improved understanding of the urea hydrolysis process in nonwater urinals to benefit w
161 was used in nonwater urinals to inhibit the urea hydrolysis reaction by lowering the pH, thereby mak
162 time the potential of marine vibrios as fast urea hydrolyzers for biotechnological applications aimin
165 asurement of potentiometric determination of urea in sera of apparently healthy and persons suffering
168 n revealed elevated levels of the metabolite urea in the OVT73 striatum and cerebellum, consistent wi
169 s (less than 500mV) and were able to monitor urea in the range of 1-1000microm, with a limit of detec
173 riments and release of (15) NH3 suggest that urea is hydrolyzed to ammonia intracellularly, then a po
174 which hydrolyzes arginine into ornithine and urea, is induced upon obesity, and silencing or loss of
176 ); the primary outcome was the change in the urea kinetic-based normalized protein catabolic rate (nP
177 , we demonstrate that postmortem human brain urea levels are elevated in a larger cohort of HD cases,
179 ifying malaria parasites, blood glucose, and urea levels in whole blood samples from thick blood film
181 Amino nitriles tethered to alkenes through a urea linkage undergo intramolecular C-alkenylation on tr
183 c acid (HBED-CC)-based PET tracer (68)Ga-Glu-urea-Lys(Ahx)-HBED-CC ((68)Ga-PSMA-11) to allow accurate
184 -targeting fluorescent dye conjugates of Glu-urea-Lys-HBED-CC was synthesized, and their biologic pro
185 ed specific tumor uptake, whereas (68)Ga-Glu-urea-Lys-HBED-CC-AlexaFluor488 (9.12 +/- 5.47 %ID/g) rev
186 the clinically relevant candidate (68)Ga-Glu-urea-Lys-HBED-CC-IRDye800CW reinforced a fast, specific
188 inhibit DAGL), which indicates the triazole ureas may affect the energy balance in mice through mult
189 ogether, our findings indicate that aberrant urea metabolism could be the primary biochemical disrupt
191 nium Bromide (CTAB) Method, Alkaline Method, Urea Method, Salt Method, Guanidinium Isothiocyanate (Gu
192 valence of the urease enzyme that hydrolyzes urea, minerals readily precipitate in nonwater urinals a
195 further 20% N saving compared with optimized urea-N rate (150 kg N ha(-1), based on N requirement by
196 se, sucrose, fructose) and nitrogen sources (urea, NH4Cl) at various concentrations to investigate fr
198 dent coronary heart disease (CHD), and blood urea nitrogen (BUN) has been shown to be a strong predic
199 later, the UNx group had higher serum blood urea nitrogen and creatinine levels and a longer electro
200 O mice exhibited lower proteinuria and blood urea nitrogen concentrations than controls indicative of
203 antly decreased survival and increased blood urea nitrogen levels compared with WT mice given the sam
204 NEVKP grafts had serum creatinine and blood urea nitrogen values comparable to their basal levels (P
205 phrectomised mice and found that their blood urea nitrogen was elevated at two days post-transfer but
206 istently elevated serum creatinine and blood urea nitrogen when compared with basal levels (P = 0.01
207 with low systolic blood pressure, high blood urea nitrogen, and history of coronary revascularization
209 ncluding age, systolic blood pressure, blood urea nitrogen, sodium, cerebrovascular disease, chronic
211 led carboxylic acids, amides, carbamates and ureas now account for a substantial number of important
213 g of a peptide-inspired chiral helical (thio)urea oligomer and a simple tertiary amine that is able t
214 dence of glutamine-bound ammonia disposal to urea on the rate of glutamine synthesis suggests that en
216 ompared with other target molecules, such as urea or creatinine, while maintaining a low detection li
219 ng solutes (urea, KCl) reduce ka comparably (urea) or more than (KCl) they increase kd, demonstrating
220 y-intense nature of hepatic and extrahepatic urea osmolyte production for renal water conservation re
222 sures of pyruvate to lactate flux (kPL ) and urea perfusion (urea AUC) that correlated with TRAMP tum
223 ansporter A3 (UT-A3) have very low levels of urea permeability and are unable to concentrate urine.
224 ransgenic expression of UT-A1 restores basal urea permeability to the level in wild-type mice but doe
227 ction event was possible using isocyanate as urea precursor and Ag(I) catalyst as alkyne activating a
230 n by increased baseline ammonia, and reduced urea production and survival after an ammonia challenge.
232 t room temperature with 0.4mL ethanol and 3g urea provided good relationship between concentration an
233 3-(3-(6-(pyrrolidin-1-yl)pyridin-2-yl)phenyl)urea (PSNCBAM-1, 2) bound the cannabinoid receptor 1 (CB
235 excretion relies on urea transporter-driven urea recycling by the kidneys and on urea production by
236 score, modified SOFA (mSOFA), the Confusion, Urea, Respiratory Rate, Blood Pressure and Age (CURB-65)
238 1% SDS followed by extraction with a 30% ACN/urea resulted in a decrease in the number of identified
239 o the conversion of imidazole to hydrophilic urea, resulting in instantaneous release of Ce6 and rapi
241 ed for the numerical characterization of the urea-sensitive hydrogel in response to the external stim
242 acterize well the responsive behavior of the urea-sensitive hydrogel subject to the urea stimulus, in
247 show that hnRNP K expression is impaired in urea soluble extracts from mutant TDP-43 cell models.
248 011, nitrogen treatment involved both foliar urea sprayings and soil application at two different lev
249 f the urea-sensitive hydrogel subject to the urea stimulus, including the distribution patterns of th
250 ncludes sulfoxides, sulfinamides, N-sulfinyl ureas, sulfoximines, and some related S-chiral derivativ
252 nia detoxification because of its support of urea synthesis, and its enhancement has potential for th
254 s proposed to characterize the hydrolysis of urea that accounts for both the ionization and denaturat
256 y and vestibular hair cells, we identified a urea-thiophene carboxamide, 1 (ORC-001), as protective a
257 e dual hydrogen-bond (H-bond) donors such as ureas, thioureas, squaramides, and guanidinium ions enjo
258 that disposal of glutamine-bound ammonia to urea (through mitochondrial glutaminase and carbamoylpho
259 hat this is due to the remarkable ability of urea to form stacking and NH-pi interactions with aromat
260 aging approach with (13)C-pyruvate and (13)C-urea to investigate differences in perfusion and metabol
261 arget protein using a gradient of denaturant urea to reveal the individual energetic contributions of
264 g the inner medullary collecting duct (IMCD) urea transporter A1 (UT-A1) and urea transporter A3 (UT-
265 duct (IMCD) urea transporter A1 (UT-A1) and urea transporter A3 (UT-A3) have very low levels of urea
266 ys also had decreased expression of the UT-A urea transporter and collectrin, which is involved in ap
267 tified significantly increased levels of the urea transporter SLC14A1 in the OVT73 striatum, along wi
268 echanism of dietary salt excretion relies on urea transporter-driven urea recycling by the kidneys an
269 ions by analyzing experimental structures of urea transporters and proteins crystallized in the prese
270 creased urea and a corresponding increase in urea transporters in the renal medulla as the result of
271 ed at various sites, we demonstrate that the urea-treated molecule has its surface residues flip insi
275 eakly acidic species such as diols and (thio)ureas, typically classified as hydrogen bonding catalyst
276 turally characterized the stable equilibrium urea unfolding intermediate of V75D at the ensemble leve
279 chanical unfolding, which combines force and urea using the optical tweezers, together with tradition
281 s a good correlation (r = 0.99) between sera urea values obtained by reference method (Enzymic colori
284 substituted dihomooxacalix[4]arene bidentate urea, voltammetric responses evolve from diffusion-contr
285 et, the plasma concentration of newly formed urea was significantly decreased compared with controls.
286 ween the two methods was higher when SDS/ACN/urea was used, compared to the 30% ACN/urea extraction,
287 y rapid hydrolysis, up to 4 g L(-1) h(-1) of urea, was observed in synthetic human urine when the bac
288 anostructure of a series of choline chloride/urea/water deep eutectic solvent mixtures was characteri
289 ts with less nontarget organ uptake than the ureas, we synthesized four (18)F-labeled inhibitors of P
290 ne and reduced concentrations of mannose and urea were discriminatory for the presentation of daytime
291 the bacteria were pretreated with 10 g L(-1) urea, whereas slow hydrolysis occurred when they were pr
294 ily available N-[(2-benzoyloxy-1-tosyl)ethyl]urea with sodium enolates of beta-oxoesters or 1,3-diket
296 logenated aminopyrazoles and their amides or ureas with a range of aryl, heteroaryl, and styryl boron
297 tes formed by treatment of the corresponding ureas with n-BuLi have been shown to activate SmI2 to a
299 ucts can be readily converted to substituted ureas without isolation, demonstrating the synthetic pot
300 eviously disclosed TAFIa inhibitors having a urea zinc-binding motif were used as the starting point
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