ライフサイエンスコーパス: ureter

1 other tonic SMCs (gastrointestinal, urethra, ureter).

2 t with IVU in one of 12 segments (lower left ureter).

3 lable in 18 of 22 patients (30 of 38 treated ureters).

4 able for 25 of 32 patients (45 of 56 treated ureters).

5 multiple tubular stenoses (e.g., bile ducts, ureters).

6 ell types in the developing and mature mouse ureter.

7 t dysplastic kidney with a dilated, tortuous ureter.

8 plex in cultured cells and in the developing ureter.

9 through the artery or retrograde through the ureter.

10 that form the wall of the forming mammalian ureter.

11 ntiating into the collecting duct system and ureter.

12 strating both patency and obstruction of the ureter.

13 omain of the UB that differentiates into the ureter.

14 ) is not dependent on fluid flow through the ureter.

15 symmetrical collecting duct tree that has no ureter.

16 erentiation in the tissues of the developing ureter.

17 he intrarenal collecting system and proximal ureter.

18 in visualization of the lower segment of the ureter.

19 ss of five different approaches to the lower ureter.

20 ureterectomy is the management of the distal ureter.

21 ysiologically relevant conditions, in intact ureter.

22 re needed to solve the dilemma of the distal ureter.

23 d urine was collected directly from the left ureter.

24 nt atrophy in the kidneys with an obstructed ureter.

25 artially rescue growth and elongation of the ureter.

26 n in the ureteropelvic junction and proximal ureter.

27 ed regions of transitional epithelium of the ureter.

28 als emanating from the tips of the branching ureter.

29 ng to the expansive growth of the kidney and ureter.

30 y play in initiating force in the guinea-pig ureter.

31 intravesical implantation of the transplant ureter.

32 ated with contraction in the portal vein and ureter.

33 atomy with single renal vessels and a single ureter.

34 g the renal excretion pathway from cortex to ureter.

35 ll cancer and cancers of the renal pelvis or ureter.

36 and it can be confused with leakage from the ureter.

37 present in the pelvicalyceal system and the ureter.

38 t Six1-deficient mice lack kidneys, but form ureters.

39 MC differentiation was observed in Six1(-/-) ureters.

40 success for strictures of transplant kidney ureters.

41 Reflux occurred in 16 of 45 ureters.

42 Reflux occurred in seven of 30 ureters.

43 of the kidneys, but severe rejection of the ureters.

44 tion of CD14 mRNA in kidneys with obstructed ureters.

45 l epithelium lining the bladder, kidneys and ureters.

46 ullary architecture, a collecting system and ureters.

47 teric buds along the Wolffian duct or duplex ureters.

48 ximal ureter, seven; midureter, four; distal ureter, 15; bladder, one) and not found in 752 locations

49 i were found in 113 locations (pyelocalyceal ureter, 86; proximal ureter, seven; midureter, four; dis

50 Ureter abnormalities occur in 1-2% of the human populati

51 e of the Wolffian ducts, and that the distal ureter abnormalities seen in Rara(-/-) Rarb2(-/-) and Re

52 ng renal hypoplasia, hydronephrosis and mega-ureter, abnormalities also seen in mice with mutations i

53 The ureter actively propels tubular fluid from the renal pel

54 ormal jets were detected from the suspicious ureter after the patient turned to the contralateral dec

55 ndicated and a stent cannot be placed in the ureter, an extra-anatomic stent (EAS) could be used to b

56 ssical open technique of securing the distal ureter and bladder cuff achieves this principle and has

57 f the various methods of managing the distal ureter and bladder cuff currently employed.

58 chnique, laparoscopic stapling of the distal ureter and bladder cuff, the "pluck" technique, and uret

59 While ureter and bladder histology appeared normal, postnatal

60 hese results suggest that Dlg1 expression in ureter and CND-associated mesenchymal cells is essential

61 rade flow of urine from the bladder into the ureter and is associated with reflux nephropathy, the ca

62 GDNF/RET signaling is required for ureter and kidney development, and cells lacking Ret are

63 tor (Th1 and Th17) and regulatory T cells in ureter and kidney tissues, and they induced T cell-media

64 roscopy for reconstructive procedures of the ureter and may represent a potential solution to some of

65 increased most of all cancers after kidney, ureter and mixed stones while bladder cancer was increas

66 strointestinal anastomosis instrument on the ureter and peri-ureteral tissue.

67 r Six1 in establishing a functionally normal ureter and provide new insights into the molecular basis

68 cyst complex, in the epithelial cells of the ureter and renal collecting system resulted in late gest

69 UPIIIa was expressed in nascent urothelia in ureter and renal pelvis of human embryos, and it is sugg

70 important for the normal peristalsis of the ureter and report an association between the expression

71 at is required for proper positioning of the ureter and that depends on Ret signaling.

72 up CT urography in the same one-third of the ureter and there were no secondary signs of a mass with

73 functional muscularization in the top of the ureter and this is followed by congenital hydronephrosis

74 clitoris, corpus cavermosum, kidney, testis, ureter and urethra have been created in the laboratory,

75 of contraction in precapillary arterioles in ureter and vas deferens.

76 dney to the bladder, causing dilation of the ureter and/or renal pelvis.

77 ds on patent connections between the kidney, ureters and bladder that are established when the ureter

78 r phenotype, is prevalent on bacteria in the ureters and bladder.

79 sion by UPEC coincides with ascension of the ureters and colonization of the kidney.

80 ephros/mesonephric duct gives rise to absent ureters and hence absent homolateral kidney; blind endin

81 turation process can result in malpositioned ureters and hydronephrosis, a common cause of renal dise

82 D patterning prompts the formation of duplex ureters and kidneys.

83 ds, resulting in the development of multiple ureters and multiplex kidneys.

84 e of urine from the bladder into one or both ureters and often up to the kidneys, and mainly affects

85 to irregular connections between the distal ureters and the bladder.

86 Precise connections between the ureters and the trigone are crucial for proper function

87 rs (AMPs) move posteriorly to form the adult ureters and, consecutively, the renal stem cells.

88 cell, 24 transitional cell renal pelvis and ureter, and 22 other kidney cancers.

89 l urothelial cancers combined (renal pelvis, ureter, and bladder cancers: adjusted IRR 2.2, 95% CI 0.

90 colorectum, kidney, liver, pancreas, bladder/ureter, and gastroesophagus, which collectively account

91 s of the urinary tract, such as the bladder, ureter, and renal pelvis.

92 the fate choice between collecting duct and ureter, and show that an environment rich in BMP4 promot

93 scle with a more minor contribution from the ureter, and that trigone formation depends at least in p

94 ithelial cells of the papillary surface, the ureter, and the urinary bladder.

95 oprotein expressed in kidney, spleen, brain, ureter, and urinary bladder.

96 esonephric tubules, ureteric bud, developing ureter, and Wolffian duct.

97 -the kidneys, intrarenal collecting systems, ureters, and bladder--and thus allows patients with hema

98 mation; pitch of 1.5) and US of the kidneys, ureters, and bladder.

99 ium that lines the renal calyces and pelvis, ureters, and bladder.

100 al organs, including the stomach, intestine, ureters, and bladder.

101 at the conclusion of the study, the kidneys, ureters, and bladders were radiographed for the presence

102 ound that LCN2 was expressed in the bladder, ureters, and kidneys of mice subject to UTI.

103 rom physiologically relevant sites (bladder, ureters, and kidneys).

104 Of 5,087 bacteria measured in bladders, ureters, and kidneys, only 7 (0.14%) were identified as

105 results in the complete absence of kidneys, ureters, and sex specific epithelial structures derived

106 nd had undergone radiography of the kidneys, ureters, and urinary bladder (KUB) and diuretic Tc-MAG3

107 Thus, the developing distal ureter appears to be a unique anatomical structure which

108 akin expression) of the distal non-branching ureter are inherent properties of this portion of the UB

109 Ureters are fundamental for keeping kidneys free from ur

110 In support of this hypothesis, ureter arrest is rescued by lowering beta-catenin levels

111 m), and stone location (upper, mid, or lower ureter) as minimisation covariates.

112 CPV was detected in the urothelium of graft ureters, associated with ureteritis and renal infection.

113 hree patients; none occurred in the unfilled ureter at index CT urography.

114 rial in the kidney and its appearance in the ureter at or below the level of the lower pole of the ki

115 uent bending and luminal constriction of the ureter at the UPJ marks the transition from a functional

116 ansplantation SSIs were deceased donor, thin ureters at kidney transplantation, antithymocyte globuli

117 ta, this indicates that, although the distal ureter (at least early in its development) retains some

118 f the stomach, small intestine, bladder, and ureters attributable to the loss of visceral SMCs disrup

119 extracellular matrix-related genes in mutant ureters before the onset of hydronephrosis.

120 met the following inclusion criteria: kidney ureter bladder (KUB) and decubitus views obtained, with

121 affecting the renal parechyma, renal pelvis, ureter, bladder and urethra; they show evidence of share

122 th urothelial carcinoma of the renal pelvis, ureter, bladder, or urethra at 16 sites in Finland, Germ

123 ncer, including cancers of the renal pelvis, ureter, bladder, or urethra, from eight hospitals in the

124 nthesis is not inhibited, BMP4 beads inhibit ureter branching and expression of Wnt 11, a target of g

125 upregulated canonical Wnt signaling disrupts ureter branching in this mutant.

126 mbryos, GDNF is sufficient to induce ectopic ureter buds in the posterior nephric duct, a process inh

127 just blocked the NP elimination through the ureter but also slowed down their transport from the med

128 tion-contraction (EC) coupling in guinea-pig ureter, by measuring membrane currents, action potential

129 -renal collecting system and the extra-renal ureter, by responding to signals in its surrounding mese

130 ex vivo organ culture suggested that ectopic ureters can regress over time, leaving behind a dysplast

131 inking-water arsenic causes renal pelvis and ureter cancer.

132 , 1.6; 95% CI, 0.8-3.0) and for renal pelvis/ureter cancers (OR, 1.7; 95% CI, 0.5-5.4).

133 For renal pelvis and ureter cancers, the adjusted odds ratios by average arse

134 In 16 ureters, chondrocyte mounds were absent in six, unilobed

135 including ureteric bud (UB) ectopia, double ureters/collecting systems, delayed primary branching of

136 the kidneys of C57BL/6 mice with obstructed ureters, compared with the contralateral kidneys, at 7 a

137 der mucosal regeneration and growth over the ureter, confirming the spontaneous development of a good

138 The mammalian ureter consists of a mesenchymal wall composed of smooth

139 The mammalian ureter contains two main cell types: a multilayered wate

140 The number of ureter contractions was significantly higher in miR-143/

141 ance on the renal system, where it regulates ureter contractions.

142 In keeping with this, isolated ureters cultured in the absence of surrounding tissues e

143 These studies provide an explanation for ureter defects underlying some forms of obstruction in h

144 Similar kidney and ureter defects were observed in RET9(Y1015F) mice that c

145 nd control cultures from finite bladder- and ureter-derived NHU cell lines at different time points u

146 etic regulator Brg1, but the role of Brg1 in ureter development is not well understood.

147 BMP4 is a mesenchymal regulator promoting ureter development, while GREM1 is necessary to negative

148 muscle progenitor cells during murine kidney-ureter development.

149 hat Brg1 expression unifies three aspects of ureter development: maintenance of the basal cell popula

150 hain (MLC) phosphorylation in the guinea-pig ureter, did not affect electrical activity or Ca2+ but s

151 Uncommitted epithelial progenitors of the ureter differentiated into intermediate cells at E14.5.

152 Ectopic insertion of a ureter draining a hypoplastic dysplastic kidney is a sig

153 f adhesins bound to immortalized vaginal and ureter epithelial cells, further reinforcing specific as

154 ation activity in mice is found to result in ureter epithelial tumors.

155 uitously (Alk3) or exclusively in the WD and ureter epithelium (Alk6).

156 Ureter epithelium developed severe hyperplasia, leading

157 Developing and adult ureters express the epigenetic regulator Brg1, but the r

158 he urothelial progenitor cells that line the ureter fail to differentiate into superficial cells, whi

159 , Ca2+ and phasic force in intact guinea-pig ureter, following physiological activation.

160 oderm results in bilateral duplex kidney and ureter formation.

161 icate that the border between the kidney and ureter forms where mesenchymal tissues originating in tw

162 branching, and delayed disconnection of the ureter from the common nephric duct (CND).

163 synergistically regulate SMC development and ureter function and that their gene products form a comp

164 he developmental expression of alphaSMA from ureter growth and elongation.

165 n initiate visceral pain in urinary bladder, ureter, gut and uterus.

166 cell carcinoma of the renal pelvis or distal ureter has been extirpated with successful oncologic out

167 supporting specific approaches to the distal ureter have been published, including implementing robot

168 eteral strictures and symptomatic retrocaval ureters have been repaired with long-term follow-up demo

169 compared to nonmalignant cell cancer of the ureter (HCV29 cells).

170 with the proximal and distal segments of the ureter in directing differentiation, the role of bone mo

171 Moreover, the peristalsis of the ureter in the absence of the kidney in the Six1-/- mouse

172 population is maintained at the tips of the ureter in the presence of signals promoting tubulogenesi

173 enally and extended caudally surrounding the ureter in the retroperitoneum.

174 Permanent ligation of the left ureter in wild-type (C3H/HeJ) mice resulted in progressi

175 rs were present in 41 partially nonopacified ureters in 20 patients.

176 Reimplantation of refluxing ureters in children has been demonstrated to provide sim

177 /- mice were found to have apparently normal ureters in the absence of a kidney, suggesting that the

178 mg) is reported to improve the depiction of ureters in the excretory phase of the examination.

179 DLGH1 is expressed in the developing ureter; in its absence, the stromal cells that normally

180 tion of UUO in rats by ligation of the right ureter, increased expression of the alpha8 integrin chai

181 s the concept of origin of the ureters (with ureters inducing renal development) by the former and th

182 chnique involved placement of the transplant ureter into a shallow, mucosa-denuded, rectangular troug

183 ssential for correct insertion of the distal ureters into the bladder, and that these events are medi

184 Stricture formation in the distal ureter is a common consequence of treatment for patients

185 Ureter maturation, the process by which the ureter is displaced to the bladder wall, represents an e

186 After the basic shape of the mammalian ureter is established, its epithelia mature and a coat o

187 the growth and development of the unbranched ureter is largely independent of the more proximal porti

188 which is expressed in the tip of the growing ureter is not.

189 -) mice exhibit renal agenesis, although the ureter is present.

190 rs and bladder that are established when the ureter is transposed from its original insertion site in

191 n, where the renal pelvis transitions to the ureter, is the most commonly obstructed site in CON.

192 abnormal development of the renal pelvis and ureter, leading to defective pyeloureteral peristalsis,

193 A lack of Six1 in the ureter led to hydroureter and hydronephrosis without ana

194 These abnormalities in the ureter led to severely impaired ureteric peristalsis.

195 shment of the model of maintained unilateral ureter ligation in mice, which is readily applicable to

196 Permanent unilateral ureter ligation represents a reproducible model for inve

197 from kidneys at 0, 3, 10, 20, and 30 d after ureter ligation showed that the tubulointerstitial injur

198 kidney, with subsequent periods of the left ureter ligation, causes irreversible right kidney failur

199 id/J (SCID) mice subjected to permanent left ureter ligation.

200 stitial fibrosis after maintained unilateral ureter ligation.

201 nto a uroplakin-positive, broad, unbranched, ureter-like 'trunk' from one end of which true collectin

202 g ducts into uroplakin-positive, unbranched, ureter-like epithelial tubules.

203 a4(-/-);Epha7(-/-) (DKO) mice display distal ureter malformations including ureterocele, blind and ec

204 for understanding the pathogenesis of human ureter malformations.

205 reduced Ret expression and apoptosis during ureter maturation and evidence of reduced retinoic acid

206 panied by reduced branching, abnormal distal ureter maturation and insertion, and smooth muscle orien

207 hymal cells is essential for ensuring distal ureter maturation by facilitating retinoic acid signalin

208 Here we show that ureter maturation depends on formation of the 'trigonal

209 t birth reveals hydronephrosis and defective ureter maturation, abnormalities that our results sugges

210 ities in ureteric bud branching or in distal ureter maturation, and no hydronephrosis.

211 Ureter maturation, the process by which the ureter is di

212 n 1 (cIAP1) to modulate caspase 3,7-mediated ureter maturation.

213 in humans and redefine the current model of ureter maturation.

214 ase of the bladder in a process that we call ureter maturation.

215 In response to signal(s) from the ureter, mesenchymal cells condense, aggregate into pretu

216 During development, ureters migrate by an unknown mechanism from their initi

217 topic BMP4 signaling is sufficient to induce ureter morphogenesis in domains of the UB normally fated

218 lear whether Six1 plays a role in regulating ureter morphogenesis.

219 that Six1 is differentially expressed during ureter morphogenesis.

220 tailbud-derived mesenchyme, is required for ureter morphogenesis.

221 In seven ureters, mounds were unilobed in five and multilobed in

222 dently, connecting at mid-gestation when the ureters move from their primary insertion site in the Wo

223 s on a complex series of events in which the ureter moves from its initial branch point on the nephri

224 In unilateral ureter obstructed mouse kidney, which is a renal fibrosi

225 es fibrosis and inflammation in a unilateral ureter obstruction (UUO) model of CKD in mice.

226 ily expression is decreased after unilateral ureter obstruction and this significant decrease in miR-

227 aluated renal inflammation during unilateral ureter obstruction in CSF-1-deficient (Csf1(op)/Csf1(op)

228 imilar results were obtained in a unilateral ureter obstruction model and in human diseased kidney bi

229 tion of type I collagen following unilateral ureter obstruction of the kidney, and quantitative prote

230 efects observed in the mutant were caused by ureter obstruction.

231 Reflux into the transplant ureter occurred in 19/27 (70%) of children tested (by ra

232 ined as the intrarenal collecting system and ureter of one kidney) basis.

233 Cultured ureters of both the wild-type and Six1 mutant become con

234 showed 108 differentially expressed genes in ureters of miR-143/145-deficient mice.

235 In addition, ureters of Six1-/- urinary tracts (i.e., lacking a kidne

236 Dysfunction of the ureter often leads to urine flow impairment from the kid

237 kidney, including duplex kidneys and double ureters, one of which is a hydroureter.

238 e been modified to accommodate the pediatric ureter, optics advanced, and access sheaths are used to

239 ffecting either the upper tract (kidneys and ureters) or lower tract (reproductive organs) of the gen

240 us in urine can be derived from the kidneys, ureter, or urinary bladder, we evaluated whether measure

241 This confirmed the ability of GDNF to induce ureter outgrowth and epithelial branching in vivo.

242 he intrarenal collecting system and proximal ureter (P < .001).

243 r role in modulating the excitability of the ureter, particularly via curtailing the action potential

244 r salts, the upper urinary tract, namely the ureter, pelvis, and calyces, could be depicted with radi

245 ent of this clinically important function of ureter (peristaltic movement of urine) is not dependent

246 In severe cases dilatation of the ureter, renal pelvis, and calyces might be seen.

247 m the WD and accessory budding from the main ureter, respectively.

248 ariant anatomy of renal arteries, veins, and ureters, respectively.

249 Examination of the ureters revealed the presence of a multi-cell layered tu

250 oved mean opacification scores in the distal ureters (right, P =.004; left, P =.006).

251 ocations (pyelocalyceal ureter, 86; proximal ureter, seven; midureter, four; distal ureter, 15; bladd

252 collecting system and that which becomes the ureter should facilitate distinguishing the developmenta

253 ed cell proliferation, and dilatation of the ureter similar to mice with kidney-specific inactivation

254 transcriptional repression, thus implicating ureter smooth muscle cell development in the pathogenesi

255 o inhibit ectopic budding from the WD or the ureter stalk by antagonizing inductive signals from the

256 cells surrounding the Wolffian duct (WD) and ureter stalk, whereas bone morphogenetic protein (BMP) t

257 othelial differentiation at the level of the ureter, suggesting that Tbx18 acts via mesenchyme as an

258 rounding the distal collecting ducts and the ureter suggests that sonic hedgehog acts as a paracrine

259 ransitional cell carcinoma of the transplant ureter (TCCtu).

260 Amyloid fibrils were isolated from a ureter that was obstructed by extensive infiltration of

261 rine from the kidneys to the bladder via the ureters that propel urine to the bladder via peristalsis

262 cts and continues into the epithelium of the ureter -- the urinary outflow tract that connects the ki

263 al and bifid branching occurs (including the ureter), the mesenchyme probably restricts lateral branc

264 In rat, but not guinea-pig ureter, three Rho-kinase inhibitors, Y-27632, HA-1077 an

265 Four patients had ectopic ureters: Three cases were ipsilateral and inserted into

266 phric kidney through the local regulation of ureter tip-specific factors.

267 There is an increase in the number of ureter tips and expansion and fusion of adjacent tips an

268 ow that GDNF increases cell proliferation in ureter tips.

269 However, no leakage from the ureter to the retroperitoneum was observed, proving that

270 ysplasia, vesicoureteral reflux, and ectopic ureters to name a few, the genetic and biochemical modul

271 g pattern of light-emitting bacteria through ureters to the kidneys.

272 ction, colonizes the bladder and ascends the ureters to the proximal tubules of the kidneys, leading

273 tead undergoes apoptosis, a crucial step for ureter transposition controlled by vitamin A-induced sig

274 ) into the intra-renal collecting system and ureter, two tissues with unique structural and functiona

275 1 in the metanephric mesenchyme, but not the ureter, under control of the Eya1 promoter.

276 would grow over the anterior surface of the ureter until they met the advancing mucosal edges from t

277 d exhibits structural defects in kidneys and ureters upon homozygosity.

278 conditionally ablated Brg1 in the developing ureter using Hoxb7-Cre and found that Brg1 expression is

279 Each calcification along the ureter was classified as a phlebolith or a ureteral calc

280 Each collecting system and ureter was divided into six segments that were assigned

281 In 12 piglets, the distal ureter was obstructed for 60 minutes, followed by intrav

282 The ureter was the earliest structure of the KTx affected by

283 The contrast medium in the renal pelvis and ureters was virtually removed from excretory phase image

284 a, decreased branching and elongation of the ureter were also observed.

285 culus and phlebolith along the course of the ureter were evaluated retrospectively and blindly for th

286 d by action potentials in guinea-pig and rat ureter were investigated.

287 t effects involving the lower segment of the ureter were seen with any technique; however, there were

288 ctility and calcium transients in intact rat ureters were compared between strains.

289 The renal collecting system and ureters were evaluated on the MR urograms.

290 While ureters were histologically normal, E15.5 Fgfr2(ST-/-) m

291 plasia results from reduced branching of the ureter, whereas the ectopic UV junction and double colle

292 reteric pathology involving all parts of the ureter with varying cause has been reported.

293 ng ureterocele, blind and ectopically ending ureters with associated hydroureter, megaureter and hydr

294 Narrowed ureters with hydronephrosis were found only in the Tl1a

295 owever, retains the concept of origin of the ureters (with ureters inducing renal development) by the

296 e most common methods of managing the distal ureter, with emphasis on contemporary oncologic outcomes

297 s to promote the elongation of the branching ureter within the metanephros, thereby promoting kidney

298 In 23 treated ureters without reflux, mounds were unilobed in 21 and m

299 In 29 treated ureters without reflux, mounds were unilobed in 28 and m

300 elops independently of the bladder, from the ureters, Wolffian ducts or a combination of both; howeve