ライフサイエンスコーパス: ureteric

1 such as solitary kidneys, hypodysplasia, or ureteric abnormalities (in a total of 29 affected indivi

2 Capsular, ureteric and vascular injuries were all significantly mo

3 sis extends our current understanding of the ureteric branch tip niche.

4 ian kidney, an epithelial progenitor pool at ureteric branch tips (UBTs) creates the urine-transporti

5 we demonstrated a requirement for Ilk during ureteric branching and cell cycle regulation in collecti

6 cultured embryonic murine kidneys decreased ureteric branching and p38MAPK activation.

7 whereas Fgfr2(UB-/-) kidneys had more severe ureteric branching defects than Frs2alpha(UB-/-), Fgfr2(

8 Hoxb7cre line (Fgfr2(UB-/-)) develop severe ureteric branching defects; however, ureteric deletion o

9 racterize the processes of nephrogenesis and ureteric branching during kidney development have many l

10 opmental disorder characterized by defective ureteric branching morphogenesis and nephrogenesis, rank

11 gfr2(UB-/-) mice have more severe defects in ureteric branching morphogenesis than previously reporte

12 Furthermore, the loss of ureteric Brg1 resulted in failure of Shh expression, whi

13 Fgfr1/2(Mes-/-) mice develop a ureteric bud (and occasionally an ectopic bud) that does

14 Absence of fgfr1 from the ureteric bud (fgfr1(UB-/-)) results in no apparent renal

15 g fibroblast growth factor receptor 2 in the ureteric bud (Fgfr2(UB-/-)) and in littermate controls.

16 Ureteric bud (UB) branching during kidney development de

17 n of both the Hdac1 and Hdac2 genes from the ureteric bud (UB) cell lineage of mice causes bilateral

18 at isolated metanephric mesenchymal (MM) and ureteric bud (UB) cells grown in three-dimensional (3D)

19 nduction of metanephric mesenchymal (MM) and ureteric bud (UB) cells.

20 s study, we showed that Adam10 deficiency in ureteric bud (UB) derivatives leads to a decrease in uri

21 s of the kidney and urinary tract, including ureteric bud (UB) ectopia, double ureters/collecting sys

22 Ureteric bud (UB) emergence from the Wolffian duct (WD),

23 Mdm2 mRNA and protein are expressed in the ureteric bud (UB) epithelium and metanephric mesenchyme

24 eloping kidney, we analyzed branching of the ureteric bud (UB) in whole kidney culture as well as in

25 d epithelial differentiation of the isolated ureteric bud (UB) independent of glial cell line-derived

26 in renal and urinary tract mesenchyme led to ureteric bud (UB) induction defects and vesicoureteral r

27 ct morphogenesis requires subdivision of the ureteric bud (UB) into the intra-renal collecting system

28 rphogenesis requires the sub-division of the ureteric bud (UB) into the intra-renal collecting system

29 in branching morphogenesis of the epithelial ureteric bud (UB) is unclear.

30 Removal of Nf2 or Lats1/2 from the ureteric bud (UB) lineage causes loss of branching morph

31 of human pluripotent stem cells (hPSCs) into ureteric bud (UB) progenitor-like cells.

32 interactions that direct arborization of the ureteric bud (UB) remain incompletely understood.

33 ate that Fras1 is expressed in the branching ureteric bud (UB), and that renal agenesis occurs in hom

34 ed cap mesenchyme surrounding the tip of the ureteric bud (UB), is downregulated after differentiatio

35 ephric mesenchyme (MM), which along with the ureteric bud (UB), is responsible for the mutually induc

36 ulture in which the MM is separated from the ureteric bud (UB), the natural inducer, can be used as a

37 cting system of the kidney, derived from the ureteric bud (UB), undergoes repetitive bifid branching

38 Defects in the growth and branching of the ureteric bud (UB), which gives rise to the collecting sy

39 cting system of the kidney develops from the ureteric bud (UB), which undergoes branching morphogenes

40 gene was inactivated in the developing mouse ureteric bud (UB).

41 develops from branching morphogenesis of the ureteric bud (UB).

42 ation of Dchs1 also reduces branching of the ureteric bud and impairs differentiation of ureteric bud

43 Nestin was not detected in ureteric bud and its derivatives throughout renal develo

44 equired for normal morphogenesis of both the ureteric bud and metanephric mesenchyme-derived structur

45 DSTYK colocalizes with FGF receptors in the ureteric bud and metanephric mesenchyme.

46 derived through the mutual induction of the ureteric bud and metanephric mesoderm, whereas the malpi

47 esult of reciprocal interactions between the ureteric bud and the blastema.

48 inductive interactions between the embryonic ureteric bud and the metanephric mesenchyme are the basi

49 genesis depend on an interaction between the ureteric bud and the metanephric mesenchyme.

50 nesis depends on the interaction between the ureteric bud and the metanephric mesenchyme.

51 of which function in the interaction of the ureteric bud and the metanephric mesenchyme.

52 e are expressed at stage E12.5 in the murine ureteric bud and/or metanephric mesenchyme.

53 nvasion of the metanephric mesenchyme by the ureteric bud at an early stage of kidney development.

54 nt in mutant mesenchyme dorsal to the mutant ureteric bud at embryonic day (E) 10.5, while mutant ure

55 Specifically, as the ureteric bud bifurcates, endothelia form across the bifu

56 t reductions were measured in the numbers of ureteric bud branch points and tips, as well as in the t

57 At the same time, the tips of the ureteric bud branches lost the typical appearance of an

58 In the RUB1 cells and ureteric bud branches of embryonic kidney, colocalizatio

59 ddition, DPP and annexin 2 colocalize in the ureteric bud branches of embryonic metanephric kidney.

60 The kidney develops by cycles of ureteric bud branching and nephron formation.

61 This is associated with reductions in ureteric bud branching and nephron number.

62 13.5 to 15.5 mice grow in size and continue ureteric bud branching and tubule formation over a 4- to

63 Ret receptor tyrosine kinase is crucial for ureteric bud branching morphogenesis during kidney devel

64 of embryonic kidneys with HDACi impairs the ureteric bud branching morphogenesis program and provoke

65 1, and interleukin-11 significantly enhanced ureteric bud branching morphogenesis.

66 re) resulted in no apparent abnormalities in ureteric bud branching or in distal ureter maturation, a

67 ized by urinary tract abnormalities, reduced ureteric bud branching, and delayed disconnection of the

68 Sema3a acts as a negative regulator of ureteric bud branching, but its function in glomerular d

69 ntrast, fgfr2(UB-/-) mice have very aberrant ureteric bud branching, thin ureteric bud stalks, and fe

70 t that is important for glomerulogenesis and ureteric bud branching.

71 ed to study individual cell behaviors during ureteric bud branching.

72 e renal hypoplasia, associated with impaired ureteric bud branching.

73 e, transgenic overexpression of Wnt9b in the ureteric bud causes reduced branching in multiple founde

74 several genetic labeling methods to observe ureteric bud cell behaviors in developing mouse kidneys.

75 PP binds to annexin 2 and 6 present in a rat ureteric bud cell line (RUB1).

76 of a dominant-negative RA receptor in mouse ureteric bud cells abolishes Ret expression and Ret-depe

77 rsely, we find that RA-receptor signaling in ureteric bud cells depends mainly on RA generated in nea

78 se around populations of cap mesenchymal and ureteric bud cells in a cyclical, predictable manner.

79 is, indicating that RA-receptor signaling in ureteric bud cells is crucial for renal development.

80 RA signaling between stromal mesenchyme and ureteric bud cells that regulates Ret expression both du

81 ferent transcripts that were enriched in the ureteric bud compared with metanephric mesenchyme and pr

82 tified several genes whose expression in the ureteric bud depends on Etv4 and Etv5, including Cxcr4,

83 trast, mice lacking talins in the developing ureteric bud developed kidney agenesis and collecting du

84 ype II receptor in mice at the initiation of ureteric bud development.

85 Troy is expressed in the ureteric bud during embryonic development.

86 F and controls outgrowth and invasion of the ureteric bud epithelia in the developing kidney.

87 n a punctate pattern at the basal surface of ureteric bud epithelia.

88 cate a novel role of Wnt7b signaling and the ureteric bud epithelium in renal medullary capillary dev

89 utively active, cAMP-independent PRKX in the ureteric bud epithelium stimulates branching morphogenes

90 acts via receptors on the Wolffian duct and ureteric bud epithelium.

91 ix1, but not Six2, Sall1, or Pax2, while the ureteric bud expresses Ret and Pax2 normally.

92 ession and Ret-dependent functions including ureteric bud formation and branching morphogenesis, indi

93 nchyme and are required for the induction of ureteric bud formation and its subsequent branching morp

94 derived neurotrophic factor (GDNF) initiates ureteric bud formation and promotes subsequent branching

95 ls that regulates Ret expression both during ureteric bud formation and within the developing collect

96 ng the metanephric blastema and inducing the ureteric bud formation but not for its normal branching.

97 Although ureteric bud formation is normal in Vangl2(Lp/Lp) embryo

98 n the Wolffian duct epithelium contribute to ureteric bud formation.

99 Branching morphogenesis of the epithelial ureteric bud forms the renal collecting duct system and

100 In mouse Sall1 mutants, the ureteric bud grows out and invades the metanephric mesen

101 tors frizzled (Fz) 4 and Fz8 lead to reduced ureteric bud growth and a reduction in kidney size, a ph

102 Ureteric bud growth and branching requires GDNF signalin

103 are excluded from the tips of the branching ureteric bud in chimeric kidneys.

104 ructures except those that were derived from ureteric bud in embryonic kidney through adult kidney.

105 ng cells can functionally substitute for the ureteric bud in these interactions.

106 To look for ureteric bud induction defects in young embryos, we asse

107 ng axis in MM development and regulating the ureteric bud induction site are incompletely understood.

108 nce of alpha8beta1 integrin, invasion by the ureteric bud into the metanephric mesenchyme is inhibite

109 in the metanephric mesenchyme at the time of ureteric bud invasion.

110 The ureteric bud is an epithelial tube that undergoes branch

111 g the growth and branching of the epithelial ureteric bud is GDNF.

112 e effect and showed significant increases in ureteric bud length and area.

113 nch points and tips, as well as in the total ureteric bud length, volume and area, while significant

114 delivery system and microinjection into the ureteric bud lumen of embryonic day 11 mouse metanephric

115 lopment of a normal kidney depends on proper ureteric bud morphogenesis, the cellular events underlyi

116 are together important for Wolffian duct and ureteric bud morphogenesis.

117 Lim 1 influences nephric duct extension and ureteric bud outgrowth by regulating and or maintaining

118 evelopment of metanephric kidney begins with ureteric bud outgrowth from the Wolffian duct (WD).

119 Altered ureteric bud outgrowth was identified in Lzts2 null embr

120 reteric bud was smaller and branching of the ureteric bud reduced.

121 e very aberrant ureteric bud branching, thin ureteric bud stalks, and fewer ureteric bud tips.

122 es Gdnf, which stimulates branching, and the ureteric bud stimulates continued growth of the mesenchy

123 signals that control gene expression at the ureteric bud tip are not well understood.

124 ureteric bud and impairs differentiation of ureteric bud tip cells into trunk cells.

125 ce the movements and divisions of individual ureteric bud tip cells.

126 omprehensive gene expression analysis of the ureteric bud tip to identify bioactive molecules.

127 of the genes that was highly specific to the ureteric bud tip was cytokine-like factor 1 (CLF-1).

128 anephric mesenchyme are required to modulate ureteric bud tip Wnt patterning in order to initiate bra

129 he Wolffian duct that give rise to the first ureteric bud tip, initiating kidney development.

130 inductive interactions and feedback between ureteric bud tips and the surrounding mesenchyme.

131 al. identify a peculiar mitotic behavior in ureteric bud tips whereby dividing cells leave the epith

132 ls, which are abnormally arranged around the ureteric bud tips, and impairment of nephron morphogenes

133 ling promotes directed cell movements in the ureteric bud tips, and suggest a model in which these ce

134 xin2 are ectopically expressed in the mutant ureteric bud tips, suggesting that upregulated canonical

135 m the surrounding mesenchyme to cells at the ureteric bud tips, via the Ret receptor tyrosine kinase

136 ion of Bmp4 in mesenchymal cells near mutant ureteric bud tips.

137 positively regulated by Ret signaling in the ureteric bud tips.

138 me and nephron, but were underrepresented in ureteric bud tips.

139 terized by both increased number and size of ureteric bud tips.

140 anching, thin ureteric bud stalks, and fewer ureteric bud tips.

141 ggregation of SIX2-positive cells around the ureteric bud tips.

142 en fluorescent protein expression throughout ureteric bud tissue.

143 bud at embryonic day (E) 10.5, while mutant ureteric bud tissues undergo high rates of apoptosis by

144 action of the metanephric mesenchyme and the ureteric bud to be the major inductive event that mainta

145 ch represses Ret levels and signaling in the ureteric bud to ensure normal ureteric morphogenesis.

146 As the ureteric bud undergoes branching and segmentation, the s

147 last growth factor receptor 2 (Fgfr2) in the ureteric bud using a Hoxb7cre line (Fgfr2(UB-/-)) develo

148 inus at embryonic day 10.5, formation of the ureteric bud was delayed, the ureteric bud was smaller a

149 rmation of the ureteric bud was delayed, the ureteric bud was smaller and branching of the ureteric b

150 tractive factor to pattern the growth of the ureteric bud within the developing kidney, and that any

151 into Fras1(bl/bl) mice, thereby reducing the ureteric bud's expression of this anti-branching molecul

152 ation, regions of mutant mesenchyme near the ureteric bud(s) express Eya1 and Six1, but not Six2, Sal

153 While the ureteric bud(s) initiates, it does not elongate or branc

154 entiated MM (unlike the upper portion of the ureteric bud) or more differentiated metanephric kidney.

155 Ret knockout mice do not form the ureteric bud, a caudal outgrowth of the Wolffian duct an

156 timized method for making a branch-competent ureteric bud, a tissue fundamental to kidney development

157 Here, we report that nephric duct, ureteric bud, and collecting duct epithelia express high

158 itors (NP), early epithelial NP derivatives, ureteric bud, and cortical stroma; p-Creb was present in

159 mesenchyme, and adjacent to the stalk of the ureteric bud, and that Vegfa was able to stimulate growt

160 etween the Wolffian duct, its derivative the ureteric bud, and their adjacent mesenchymes.

161 niche, and Fgf9, secreted from the adjacent ureteric bud, are necessary and sufficient to maintain p

162 of the Wt1 gene eliminates outgrowth of the ureteric bud, but Gdnf has been identified as a target o

163 nsistently, TfR1 provided transferrin to the ureteric bud, but not to the capsule or the stroma.

164 While SCF is restricted to the ureteric bud, c-kit-positive cells are located within th

165 ix molecule FRAS1, normally expressed by the ureteric bud, leads to bilateral renal agenesis in human

166 mesoderm, nephric duct, mesonephric tubules, ureteric bud, pretubular aggregates and their derivative

167 distribution in the caudal Wolffian duct and ureteric bud, similar to Ret(-/-) cells, revealing a cel

168 wever, once Gdnf stimulates branching of the ureteric bud, the Flk1-dependent angioblast signal is no

169 To determine roles of FGFR1 and FGFR2 in the ureteric bud, we used a conditional targeting approach.

170 d cell behavior in the branching tips of the ureteric bud, which we term "mitosis-associated cell dis

171 he newly formed epithelial bud, known as the ureteric bud, will continue to branch ultimately differe

172 Branching of ureteric bud-derived epithelial tubes is a key morphogen

173 These data suggest that ureteric bud-derived SCF elicits growth-promoting effect

174 elopment from metanephric mesenchyme but not ureteric bud.

175 pression of a stabilized beta-catenin in the ureteric bud.

176 pends on precise control of branching of the ureteric bud.

177 that later emerges as the tip of the primary ureteric bud.

178 ffect more mature structures or cells in the ureteric bud.

179 embryonic circulation form a ring around the ureteric bud.

180 ric mesenchyme to inductive signals from the ureteric bud.

181 ing the inductive signals emanating from the ureteric bud.

182 d as simply the non-branching portion of the ureteric bud.

183 GDNF supplied only by the Wolffian duct and ureteric bud.

184 in turn elicits an inductive signal from the ureteric bud.

185 including the proximal tubular cells and the ureteric bud.

186 rentiate in response to WNT signals from the ureteric bud.

187 nesis and Vangl2 is known to be expressed in ureteric bud/collecting duct and metanephric mesenchymal

188 ecting ducts: galectin-3 is expressed in the ureteric bud/collecting duct lineage during nephrogenesi

189 s of the Wolffian ducts and the duct derived ureteric bud/collecting duct system in an undifferentiat

190 rucial for controlling Ret expression in the ureteric bud; however, the mechanism by which retinoid-s

191 The ureteric buds (UBs) in mutants emerge as doublets from t

192 MM leads to kidneys with cranially displaced ureteric buds along the Wolffian duct or duplex ureters.

193 demonstrated that ErbB4 is expressed in the ureteric buds and developing tubules of embryonic rat ki

194 Inductive interactions between the branching ureteric buds and the metanephric mesenchyme lead to mes

195 tanephros for both proper development of the ureteric buds and the patterning of renal vesicles for n

196 sexpression of GDNF in the Wolffian duct and ureteric buds resulted in formation of multiple, ectopic

197 ds to a virtual absence of MM and unbranched ureteric buds that are occasionally duplex.

198 ic kidneys that were caused by supernumerary ureteric buds that fail to separate from the wolffian du

199 ce and cell migration, develop supernumerary ureteric buds that remain inappropriately connected to t

200 resumably enables the nephronectin-deficient ureteric buds to invade the metanephric mesenchyme and b

201 In genetically mosaic mouse ureteric buds, competition between phenotypically mutant

202 efects but had cranially displaced or duplex ureteric buds, probably as a result of decreased Bmp4 ex

203 Spry1(-/-) embryos have supernumerary ureteric buds, resulting in the development of multiple

204 one from mouse E12.5 and one from rat E13.5 ureteric buds.

205 odality for the treatment of renal and upper ureteric calculi.

206 dney mRNA in mice with Ilk deficiency in the ureteric cell lineage.

207 dentified genes that are regulated by Ilk in ureteric cells using a whole-genome expression analysis

208 ailable to the urologist in the treatment of ureteric colic as well as the advantages and disadvantag

209 The management of ureteric colic has changed significantly over the past t

210 e passage for people managed expectantly for ureteric colic, but emphasised the need for high-quality

211 weeks for patients with expectantly managed ureteric colic.

212 We find that (1) non-UPEC do not affect ureteric contractility, (2) impairment of contractility

213 96 and 536) can subvert this role and reduce ureteric contractility.

214 r signaling (Frs2alpha(UB-/-)) leads to mild ureteric defects.

215 Mice with ureteric deletion of both Fgfr2 and Frs2alpha (Fgfr2/Frs

216 ha, compound mutant mice were generated with ureteric deletion of Fgfr1 and with Fgfr2(LR/LR) point m

217 severe ureteric branching defects; however, ureteric deletion of fibroblast growth factor receptor s

218 s required for early branching events of the ureteric duct that occur prior to the onset of nephrogen

219 abnormality of early branching events of the ureteric duct.

220 e Esrrg protein is detected throughout early ureteric ducts as cytoplasmic/sub-membranous staining; w

221 een three lineages (stromal, mesenchymal and ureteric) ensures correct nephron progenitor self-renewa

222 Overexpression in ureteric epithelial cell membranes of an inhibitory pMyr

223 amina propria cells directly adjacent to the ureteric epithelium and differentiated smooth muscle cel

224 key nephrogenic progenitor populations: the ureteric epithelium and the cap mesenchyme.

225 x reciprocal tissue interactions between the ureteric epithelium and the mesenchyme.

226 These include the ureteric epithelium of the collecting duct network, the

227 ly, the linked BAC confers expression in the ureteric epithelium, whereas sequences within any of the

228 system, which originates from the branching ureteric epithelium.

229 transcriptionally active beta-catenin in the ureteric epithelium.

230 as a key regulator of Gdnf expression during ureteric induction and branching morphogenesis.

231 ssues, suggesting a mechanism underlying the ureteric induction and VUR phenotypes.

232 sites into the bladder, consistent with the ureteric induction defects.

233 The vesico-ureteric junction (VUJ) forms through a complex developm

234 Pelvi-ureteric junction obstruction is mostly detected prenata

235 rosis and failure to develop a patent pelvic-ureteric junction.

236 gfr2 and Frs2alpha have crucial roles in the ureteric lineage, they appear to act separately and addi

237 ationship between Fgfr2 and Frs2alpha in the ureteric lineage.

238 ntial for developmental specification of the ureteric mesenchyme and ureteric smooth muscle cells.

239 2(LR/LR) mice also had subsequent defects in ureteric morphogenesis, including dilated, hyperprolifer

240 gnaling in the ureteric bud to ensure normal ureteric morphogenesis.

241 s in vitro and in vivo in a mouse Unilateral Ureteric Obstruction (UUO) model.

242 ished a murine model of fibrosis (unilateral ureteric obstruction (UUO)).

243 Sdc4-null mice were subjected to unilateral ureteric obstruction and aristolochic acid nephropathy (

244 n, injury, and fibrosis following unilateral ureteric obstruction in mice.

245 ild-type C57BL/6 mice (n=14), and unilateral ureteric obstruction was performed later to induce renal

246 Following unilateral ureteric obstruction, PAR2-deficient mice displayed redu

247 In a murine model with unilateral ureteric obstruction, pretreatment with dasatinib signif

248 el of progressive renal fibrosis (unilateral ureteric obstruction, UUO), and absence of galectin-3 pr

249 collecting system to severe injury following ureteric obstruction.

250 nterstitial fibrosis in mice with unilateral ureteric obstruction.

251 ry models: folate nephropathy and unilateral ureteric obstruction.

252 ent (EAS) could be used to bypass a complete ureteric obstruction.

253 model of renal fibrosis caused by unilateral ureteric obstruction.

254 Surgeon-controlled robotic management of ureteric pathology involving all parts of the ureter wit

255 y has an expanding role in the management of ureteric pathology.

256 ities in the ureter led to severely impaired ureteric peristalsis.

257 ion to some of the drawbacks associated with ureteric reconstruction.

258 and urinary tract (CAKUT), including vesico-ureteric reflux (VUR), are major causes of ESRD in child

259 or bladder augmentation, colposuspension and ureteric reimplantation are reviewed.

260 on of a bulking agent and minimally invasive ureteric reimplantation.

261 ureteric volume and surface area and longer ureteric segments than control mice.

262 nascent ureteric urothelium and ending with ureteric smooth muscle cell differentiation, with Tshz3

263 specification of the ureteric mesenchyme and ureteric smooth muscle cells.

264 gulates differentiation and proliferation of ureteric smooth muscle progenitor cells during murine ki

265 Mutation in nephrons, ureteric smooth muscle, and mesenchyme surrounding the l

266 In ureteric smooth muscle, peristaltic waves that occur as

267 Moreover, in ureteric smooth muscle, the circular smooth muscle cells

268 All ureteric stenoses were treated by surgical reconstructio

269 ologic complications (MUCs: urinary leak and ureteric stenosis [US]) in kidney transplants procured f

270 survival after percutaneous ureteroplasty of ureteric stenosis after renal transplantation and to com

271 ith percutaneous ureteroplasty of transplant ureteric stenosis were not significantly worse than thos

272 , to reduce the incidence of urine leaks and ureteric stenosis.

273 plant recipients who developed postoperative ureteric stenosis.

274 of transplant recipients with no history of ureteric stenosis.

275 mes to those of patients who did not develop ureteric stenosis.

276 managed surgically or by means of long-term ureteric stent placement.

277 n ureteroneocystostomy over a double pigtail ureteric stent was performed in all transplants, and ure

278 Prophylactic ureteric stenting in renal transplantation reduces major

279 number needed to treat = 13) by prophylactic ureteric stenting.

280 Ureteric stents have been successfully used to treat suc

281 stent was performed in all transplants, and ureteric stents were removed after approximately 6 weeks

282 undergoing expectant management for a single ureteric stone identified by CT at 24 UK hospitals.

283 ular, ureteropelvic junction obstruction and ureteric stricture disease.

284 Ureteric stricture is the most common urological complic

285 ovel EAS system in a patient with transplant ureteric stricture when antegrade stent placement or sur

286 d beta-catenin are elevated in the nuclei of ureteric, stromal, and mesenchymal cells within dysplast

287 tosis-associated cell dispersal." Premitotic ureteric tip cells delaminate from the epithelium and di

288 Six genes with expression in ureteric tip cells, including Wnt11, were downregulated,

289 Given the high rate of cell division in ureteric tips, this cellular behavior causes extensive e

290 Analysis of obstructive ureteric tissue resected from children with congenital i

291 ltured embryonic kidneys, without increasing ureteric tree branching, and promoted mesenchymal-to-epi

292 identifying novel mediators, the tips of the ureteric tree were isolated and microarray analyses were

293 which, in turn, causes mispatterning of the ureteric tree, while delaying and disorganizing nephroge

294 s work showed that Wnt7b is expressed in the ureteric trunk epithelium and activates canonical Wnt si

295 ression of Ret and its downstream targets in ureteric trunks, and exhibited upregulation of Ret/Etv4/

296 Furthermore, dysplastic ureteric tubules that were surrounded by high levels of

297 dney requires reciprocal signaling among the ureteric tubules, cap mesenchyme and surrounding stromal

298 with sonic hedgehog secreted by the nascent ureteric urothelium and ending with ureteric smooth musc

299 A ureteric-vaginal fistula developed 2 weeks after uterus

300 Furthermore, these mice had decreased ureteric volume and surface area and longer ureteric seg