1 There is an
urgent need to accurately model how environmental change
2 The second concerns the
urgent need to address ethical issues when evaluating th
3 There is an
urgent need to address manpower and infrastructural defi
4 study in the scientific community due to the
urgent need to address many of the most important questi
5 bate, on both sides, continues to hamper the
urgent need to address the diverse and pressing challeng
6 The results support an
urgent need to address vaccine hesitancy in policy dialo
7 Therefore, there is an
urgent need to assess the MRI characteristics of PML in
8 Hence, there is an
urgent need to be prepared with vaccines and therapeutic
9 There is an
urgent need to better define the natural history of FPIE
10 ronment to the leukemic cells, indicating an
urgent need to better understand the factors that promot
11 A broader theme that emerged was the
urgent need to bring the glycosciences back into the mai
12 There is an
urgent need to build mitigation capacity where amphibian
13 There is an
urgent need to build the research capacity of this field
14 Therefore, there is
urgent need to characterize dysregulated TK signaling ax
15 e, sequencing of tumor samples is driving an
urgent need to classify whether or not mutations seen in
16 eries, and dental implantations, there is an
urgent need to combat implant-associated infection.
17 There is an
urgent need to come up with a vaccine that will curtail
18 Given our
urgent need to conserve both wildlife and the food secur
19 Therefore, there is an
urgent need to continue researching in order to discover
20 Available data in athletes have indicated an
urgent need to control for testing conditions such as hy
21 Clearly, there is an
urgent need to define common standards for data analysis
22 This challenge shows the
urgent need to define novel strategies to provide long-t
23 tical role in the catalysis, and there is an
urgent need to define the actual metal used by MetAP in
24 xt of little clinical evidence, indicates an
urgent need to define the appropriate use of these medic
25 Findings also indicate an
urgent need to destigmatize DUD and educate the public,
26 Nonetheless, there remains
urgent need to determine the basis for sepsis-related co
27 serious at higher temperatures, there is an
urgent need to determine the mortality projection of spe
28 There is an
urgent need to determine whether oversulfated chondroiti
29 Therefore, there is an
urgent need to develop a high-throughput and efficient s
30 There is thus an
urgent need to develop a representative animal model to
31 Therefore, there is an
urgent need to develop alternative technologies.
32 Thus, there is an
urgent need to develop alternative, egg-independent vacc
33 There is an
urgent need to develop an efficacious and affordable vac
34 There is an
urgent need to develop and validate noninvasive tests th
35 There is an
urgent need to develop antifibrotic therapies for chroni
36 Currently there is an
urgent need to develop antitrypanosomal therapy due to t
37 Clearly, there is an
urgent need to develop better tolerated and more effecti
38 There is an
urgent need to develop bioinformatics tools as to gain i
39 There is an
urgent need to develop biomarkers that predict patient p
40 There is an
urgent need to develop both novel non-chemical approache
41 Our results emphasize the
urgent need to develop cheap protein alternatives to bus
42 Therefore, there exists an
urgent need to develop effective treatment strategies sp
43 humans is clearly warranted, and there is an
urgent need to develop effective vaccines against them.
44 There is an
urgent need to develop fertility-related information ada
45 There is an
urgent need to develop guidelines for the expansion of o
46 There is an
urgent need to develop long-lasting alternative insectic
47 Therefore, there is an
urgent need to develop mechanism-based novel approaches
48 There is an
urgent need to develop methods to accurately and rapidly
49 Therefore, there is an
urgent need to develop methods to identify the populatio
50 There is an
urgent need to develop nanocarriers for the treatment of
51 There is
urgent need to develop new acceleration techniques capab
52 l drugs such as chloroquine, demonstrates an
urgent need to develop new and alternative approaches to
53 While there is an
urgent need to develop new and effective drugs for treat
54 There is now an
urgent need to develop new and effective treatments.
55 Consequently, there is an
urgent need to develop new antimicrobials to treat A. ba
56 There is an
urgent need to develop new classes of antibiotics to tac
57 r this deadly disease; therefore there is an
urgent need to develop new diagnostics to accurately det
58 It is an
urgent need to develop new drugs for Mycobacterium tuber
59 stance to available antibiotics, there is an
urgent need to develop new drugs.
60 There is an
urgent need to develop new pathogenic R5 simian/human im
61 There is an
urgent need to develop new pathophysiology-oriented ther
62 Therefore, there is an
urgent need to develop new sources of insulin-producing
63 ival with current therapies, emphasizing the
urgent need to develop new therapeutic approaches.
64 There is an
urgent need to develop new therapeutics for this disease
65 usually die within one year, emphasizing an
urgent need to develop new treatment strategies for this
66 However, there remains an
urgent need to develop new vaccines for HIV/AIDS, malari
67 of cruzain inhibitors has been driven by the
urgent need to develop novel and more effective drugs fo
68 istant strains of P. aeruginosa, there is an
urgent need to develop novel antibiotic and anti-virulen
69 There is an
urgent need to develop novel antimicrobial therapies to
70 ehydration and supporting care suggesting an
urgent need to develop novel approaches to improve stand
71 Thus, there is an
urgent need to develop novel therapeutic interventions t
72 ss the blood-brain barrier, underscoring the
urgent need to develop novel therapeutic strategies.
73 There is an
urgent need to develop novel therapeutics for suppressin
74 Thus, there is an
urgent need to develop novel therapeutics for this disea
75 new antibiotics virtually empty, there is an
urgent need to develop novel therapeutics.
76 There is an
urgent need to develop novel therapies for controlling c
77 There is an
urgent need to develop novel therapies for controlling r
78 Given the
urgent need to develop novel, potent antibiotics, the re
79 Therefore, there is an
urgent need to develop novel, specific amyloidophilic ra
80 Our study provides an early warning of the
urgent need to develop policies that manage nitrogen emi
81 These include an
urgent need to develop pretest education for all pregnan
82 ral therapy approved for humans, there is an
urgent need to develop prophylactic and therapeutic opti
83 There is an
urgent need to develop regimens that incorporate chemoth
84 eum and other fossil fuels, has motivated an
urgent need to develop renewable, carbon-neutral, econom
85 Thus, there is an
urgent need to develop second-generation M2 inhibitors t
86 There is, therefore, an
urgent need to develop single-dose and long-lasting rabi
87 However, there is an
urgent need to develop substitutes for pure Pt catalysts
88 Consequently, there is an
urgent need to develop targeted therapies capable of eli
89 There is an
urgent need to develop technologies that use renewable e
90 There is an
urgent need to develop therapies that modify both the un
91 There is an
urgent need to develop therapies that slow down the prog
92 The first was the
urgent need to differentiate between tumor cell and tumo
93 e of Mycobacterium tuberculosis, there is an
urgent need to discover antituberculosis agent with nove
94 Therefore, there is an
urgent need to discover effective therapeutic agents for
95 There is therefore an
urgent need to discover more effective targets for PEL m
96 There is an
urgent need to discover new anti-tubercular agents with
97 Our results highlight the
urgent need to document and understand Neotropical salam
98 The NESARC-III data indicate an
urgent need to educate the public and policy makers abou
99 There is an
urgent need to either significantly expand the R55/R56 m
100 There is an
urgent need to elicit and validate highly efficacious ta
101 the widespread plight of coral reefs and the
urgent need to enact conservation measures.
102 To meet this demand, there is an
urgent need to enhance the accessibility and reach of su
103 There is an
urgent need to ensure the robustness of fractional-dose
104 There is an
urgent need to establish national risk assessment system
105 Thus, there is an
urgent need to establish standard panels of HIV-1 refere
106 There is an
urgent need to establish sustainable technologies for in
107 This change indicates the
urgent need to evaluate and document ophthalmic manifest
108 Raquel Gonzalez and colleagues highlight an
urgent need to evaluate antimalarials that can be safely
109 ctor for VL treatment success, suggesting an
urgent need to evaluate the recently proposed optimal al
110 individuals with mental illness indicates an
urgent need to examine HIV risk behavior in this populat
111 ise in antimicrobial resistance, there is an
urgent need to examine market mechanisms that are approp
112 There is an
urgent need to expand basic science approaches for negle
113 There is an
urgent need to expand the surgical care delivery system
114 Therefore, there is an
urgent need to explore genetic factors involved in this
115 Thus, there is an
urgent need to explore new approaches for modulating the
116 There is thus an
urgent need to explore new control solutions, one of whi
117 of emerging infectious diseases, there is an
urgent need to facilitate multidisciplinary research in
118 tructure-structure alignment algorithm is in
urgent need to facilitate the comparative study.
119 gainst disseminated disease, and there is an
urgent need to fill this gap.
120 s and drug resistant mutants, highlights the
urgent need to find antivirals with novel mechanisms of
121 Consequently, there is an
urgent need to find better mechanisms of inhibiting myel
122 Therefore there is an
urgent need to find new therapeutic strategies to treat
123 ion transitions are dramatic and point to an
urgent need to focus on preventive approaches in health
124 In particular, there is an
urgent need to focus our efforts on effective therapeuti
125 nce factors that we discover underscores the
urgent need to halt the advance of pathogenic chytrids a
126 There is an
urgent need to help people with serious mental illness t
127 Thus, there is an
urgent need to identify and characterize aberrantly expr
128 Therefore, there is an
urgent need to identify and target signaling molecules w
129 barriers and infected humans underscores the
urgent need to identify anti-TSE drugs.
130 To overcome this shortcoming, there is an
urgent need to identify appropriate surrogate endpoints.
131 There is an
urgent need to identify biomarkers for hepatocellular ca
132 ce with this therapeutic class highlights an
urgent need to identify biomarkers of HAP sensitivity, i
133 There is an
urgent need to identify electrocardiographic characteris
134 There is an
urgent need to identify environmental risk and protectiv
135 arily to metastatic spread, highlighting the
urgent need to identify factors involved in this progres
136 nd flagella play in human disease creates an
urgent need to identify genes involved in ciliary assemb
137 adjunctive treatments for CM, so there is an
urgent need to identify new targets for therapy.
138 There is an
urgent need to identify new therapeutic opportunities fo
139 There is an
urgent need to identify new treatments for tuberculosis
140 Therefore, there is an
urgent need to identify new, safe, and targeted therapeu
141 As such, there is an
urgent need to identify novel drugs to treat TB infectio
142 There is an
urgent need to identify novel risk factors and primary p
143 approved in the past 2 decades, there is an
urgent need to identify novel targets and therapeutic st
144 KIT/PDGFRA kinase inhibitors and there is an
urgent need to identify novel therapeutic strategies.
145 Thus, there is an
urgent need to identify potential underlying mechanisms
146 There is an
urgent need to identify relevant tumor markers showing h
147 There is an
urgent need to identify reliable biomarkers of amyotroph
148 ed with many human diseases, and there is an
urgent need to identify specific DUBs associated with th
149 Therefore, there is an
urgent need to identify specific targets and effective p
150 ariants in the clinical setting, there is an
urgent need to identify the best variant caller(s) from
151 There is an
urgent need to identify therapeutic targets for BLBC, be
152 aving but limited resource, there remains an
urgent need to identify those patients at greatest risk
153 ing SCID patients early in life, there is an
urgent need to identify validated approaches through pro
154 Our analyses underline the
urgent need to implement global strategies to measure se
155 heria diagnostics EQA alarmingly reflect the
urgent need to improve laboratory performance in diphthe
156 national quality-control study underline the
urgent need to improve methods used to monitor HDV virem
157 timal anticoagulation control, suggesting an
urgent need to improve oral anticoagulation care for mos
158 Consequently there is an
urgent need to improve our understanding of the mechanis
159 There is an
urgent need to improve outcomes and reduce costs for pat
160 rates of antibiotic resistance, there is an
urgent need to improve prevention of pneumococcal diseas
161 There is an
urgent need to improve the current inconsistent--sometim
162 y and chronic airway diseases, which face an
urgent need to improve the level of disease control, enh
163 of pancreatic cancer increases, there is an
urgent need to improve the training of surgeons and deve
164 ith low-access to HCV services emphasises an
urgent need to include resource-limited settings in the
165 The study emphasizes the
urgent need to incorporate climate change into the IUCN
166 There is therefore an
urgent need to increase multisectoral coverage of qualit
167 There is an
urgent need to increase the number of coinfected patient
168 We highlight the
urgent need to integrate a broader perspective into loca
169 ediatric antiretroviral therapy, there is an
urgent need to introduce a simple, low-cost infant human
170 There is therefore an
urgent need to investigate novel vaccination approaches.
171 This prompts an
urgent need to investigate the molecular mechanisms unde
172 ely for drug and vaccine design, there is an
urgent need to make the link between these DNA sequences
173 These findings highlight an
urgent need to manage the sustainability of game hunting
174 To optimize their use, there has been an
urgent need to minimize both warm and cold ischemia, whi
175 The
urgent need to minimize the potential harm deriving from
176 The
urgent need to mitigate climate change invokes both oppo
177 ems resembling kidney characteristics are in
urgent need to model disease as well as to establish rel
178 This work demonstrates the
urgent need to monitor Lm strains at the global level an
179 primary productivity (NPP), emphasizing the
urgent need to monitor the impacts of climate change.
180 r by adaptation or by migration, there is an
urgent need to obtain estimates of dispersal distance.
181 There is an
urgent need to offer targeted, age-appropriate routine H
182 These results reinforce the
urgent need to overcome barriers to scaling up pediatric
183 e of these two recent papers in light of the
urgent need to produce an efficacious HIV vaccine and di
184 These data show an
urgent need to provide direct experimental validation of
185 ite of the simplicity of the concept and the
urgent need to provide such a treatment to patients, the
186 There is an
urgent need to push back against the environmental force
187 There is an
urgent need to quantify anthropogenic influence on fores
188 Analogously, there is an
urgent need to quantify the mechanics of emerging electr
189 ated for coronavirus infections, there is an
urgent need to rapidly identify potential therapeutics t
190 These results support an
urgent need to re-evaluate current global guidelines for
191 urrent pedagogic models, and underscores the
urgent need to realign and synergize these models to ref
192 There is an
urgent need to reassess how to approach anemia control i
193 Climate change imposes an
urgent need to recognise and conserve the species likely
194 -resistant Enterobacteriaceae highlights the
urgent need to reduce carbapenem dependence.
195 Our results suggest an
urgent need to reform African governments' and foreign a
196 s and other soft tissue defects, there is an
urgent need to regenerate skin.
197 There is
urgent need to regularly monitor and improve the availab
198 There is an
urgent need to report the successes and failures of thes
199 There is an
urgent need to rethink policies and strategies to combat
200 There is an
urgent need to rethink the immunology of Mycobacterium t
201 Conclusions pointed out an
urgent need to review legislative limits in food matrice
202 However, there is an
urgent need to rigorously estimate actual mortality rate
203 These data suggest an
urgent need to scale up access to quality HIV prevention
204 There is therefore an
urgent need to scale up vector control and access to hea
205 f equilibrium, and so there is a growing and
urgent need to sensitize students and citizens to the im
206 There is an
urgent need to standardize processes used to develop cli
207 There is an
urgent need to standardize reporting of methods and defi
208 implications of optical imaging, there is an
urgent need to standardize surgical navigation tools and
209 This implies an
urgent need to systematically evaluate many aspects of t
210 Thus, there is an
urgent need to test novel therapeutic agents to countera
211 Hence our study emphasizes the
urgent need to test the inflammatory properties of trans
212 Consequently, there is an
urgent need to translate diagnostic strategies to establ
213 There is an
urgent need to translate these assays to the study of ce
214 This strongly suggests that there is an
urgent need to treat breast cancer with a personalized a
215 f the EGFR-PI3K/Akt pathway, underscores the
urgent need to understand alternative downstream pathway
216 There is an
urgent need to understand and establish the pharmacokine
217 ansplantation from older donors, there is an
urgent need to understand how brain death leads to kidne
218 There is an
urgent need to understand how the paradigm that has guid
219 Given the
urgent need to understand how the thousands of loci that
220 containing this water annually, creating an
urgent need to understand its effects on bird health.
221 There is an
urgent need to understand signaling cascades that promot
222 There is an
urgent need to understand the basis of resistance to opt
223 to urbanization and development there is an
urgent need to understand the dynamics of vector-borne d
224 There is an
urgent need to understand the effect of such disturbance
225 There is an
urgent need to understand the factors that contribute to
226 ratures and decreasing rainfall, there is an
urgent need to understand the influence of climate chang
227 Therefore there is an
urgent need to understand the mechanisms by which glucoc
228 treat RVFV infection, and thus, there is an
urgent need to understand the mechanisms by which the vi
229 Indeed, there is an
urgent need to understand the mechanisms linking unhealt
230 There is an
urgent need to understand the mechanisms of A. baumannii
231 stant (MDR) tuberculosis (TB) highlights the
urgent need to understand the mechanisms of resistance t
232 cobacterium tuberculosis has underscored the
urgent need to understand the molecular mechanisms of im
233 To mitigate or eliminate PWMI, there is an
urgent need to understand the pathological mechanism(s)
234 hways, medicinal chemistry efforts remain an
urgent need to yield selective and efficacious AP-1 inhi