ライフサイエンスコーパス: urine osmolality

1 with a decreased urine volume and increased urine osmolality.

2 er intake and urine volume, alongside higher urine osmolality.

3 ot accompanied by a proportional increase in urine osmolality.

4 s 9-fold greater than in wild-type mice, and urine osmolality (194 mosm) was 8.4-fold reduced.

5 , despite better renal free water excretion (urine osmolality 343+/-101 mOsm/kg versus 475+/-136; P<0

6 AQP2(+/+) mice (1.6 ml/day) and had reduced urine osmolality (400 vs. 1800 mosmol).

7 more fluid than wild-type mice and had lower urine osmolality (505 +/- 40 vs. 1081 +/- 68 milliosmola

8 Maximum urine osmolality after a 36-h water deprivation was (in

9 ed therapeutic concentrations in the kidney, urine osmolality after administration of 1-deamino-8-D-a

10 Under basal conditions, plasma and urine osmolalities and urine volumes were similar betwee

11 izygous male pups showed a decrease in basal urine osmolalities and were unable to concentrate their

12 e induced similar antidiuresis and increased urine osmolality and aquaporin-2 abundance.

13 n a significant increase in water retention, urine osmolality and aquaporin-2 expression and phosphor

14 P levels, water and sodium reabsorption, and urine osmolality and decreased urine output (P </= 0.04,

15 ne cAMP levels, free water reabsorption, and urine osmolality and increased urine output (P </= 0.03

16 P levels, water and sodium reabsorption, and urine osmolality and increased urine output, while raxib

17 Furosemide significantly decreased urine osmolality and urea clearance, and increased blood

18 gents augment free water clearance, decrease urine osmolality, and correct serum [Na+] and serum osmo

19 and observed marked antidiuresis, increased urine osmolality, and increased solute-free water reabso

20 Urine volume, urine osmolality, and urinary excretion of sodium and cr

21 cantly greater urine flow rate and decreased urine osmolality as compared with control rats at compar

22 ral abnormalities, mutant mice exhibited low urine osmolality at baseline and after water restriction

23 , and [-/-] 2,616+/-229 (P < 0.025), whereas urine osmolalities before water deprivation did not diff

24 beta=0.11; 95% CI, 0.01 to 0.20; P=0.03) and urine osmolality (beta=0.08; 95% CI, 0.05 to 0.10; P<0.0

25 Changes in body mass, urine osmolality, body temperature, and thirst were moni

26 creased urine output by 3-5-fold and reduced urine osmolality by approximately 2-fold compared to veh

27 had a reduced urine flow and two-fold higher urine osmolality during the first 12 hours of treatment

28 ine specific gravity (USG), urine color, and urine osmolality have been widely advocated for screenin

29 Notably, basal urine osmolalities in both wild-type and UT-A1(+/+)/UT-A

30 17-AAG increased urine osmolality in AQP2(T126M/-) mice by >300 mosmol bu

31 )-14 also increased urine output and reduced urine osmolality in mice given free access to water.

32 The increase in urine osmolality in response to water deprivation or vas

33 UTB(inh)-14 did not reduce urine osmolality in UT-B knockout mice.

34 However, the urine osmolality increase was greater within the physiol

35 Concurrently, urine osmolality increased from 242 +/- 60 to 1267 +/- 3

36 restriction of rats or mice led to increased urine osmolality, increased Sgk1 expression, increased e

37 urine outflow with concomitant reduction of urine osmolality, indicating a purely aquaretic effect a

38 ntake and urine volume, as well as increased urine osmolality lasting 4 months.

39 ter than that in wild-type litter mates, and urine osmolality (<275 milliosmol) was much lower than i

40 mistry profiles, spleen function biomarkers, urine osmolality, neurodevelopment, transcranial Doppler

41 ion of the VR agonist dDAVP did not increase urine osmolality of AC6-deficient mice to the levels of

42 ots of plasma AVP concentration ([AVP]P) vs. urine osmolality (OsmU) were fitted to a sigmoidal curve

43 Total water intake (P = 0.002), urine osmolality (P < 0.001), and hypohydration prevalen

44 0.03) and polyuria (P < 0.04), with a lower urine osmolality (P < 0.003) as compared to Nhe3+/+ mice

45 However, urine osmolality remained significantly decreased.

46 molality remained normal (310-330 mOsm), and urine osmolality rose to >2500 mOsm.

47 is phenotype is the consequence of decreased urine osmolality secondary to renal vasopressin resistan

48 output, solute and urea excretion, serum and urine osmolality, serum creatinine, 24-h creatinine clea

49 ume, but there was a significant increase of urine osmolality, suggesting that DI may be caused by a

50 (GW3965) in WT mice elicited an increase in urine osmolality, suggesting that LXRbeta is a key recep

51 t both serine-256 and serine-269), and lower urine osmolality than wild-type mice.

52 ng defect with serum hyperosmolality and low urine osmolality that was not increased by a V2 vasopres

53 ater in UT-B- deficient mice (p < 0.01), and urine osmolality (U(osm)) was lower (1532 +/- 71 versus

54 At basal condition, urine osmolality (Uosm) was significantly lower (P < 0.0

55 , and index tests included USG, urine color, urine osmolality, urine cloudiness, additional dipstick

56 urine output and fluid intake, and increases urine osmolality, urine sodium concentration, and plasma

57 ia is further differentiated on the basis of urine osmolality, urine sodium level, and volume status.

58 Urine osmolality was determined with the use of freezing

59 ing capacity: Urine flow rate was higher and urine osmolality was lower than control rats despite an

60 water-deprived knockout mice was <10 mM, and urine osmolality was not increased by the V2 agonist DDA

61 In rats injected with lipopolysaccharide, urine osmolality was reduced by ~40%, along with medulla

62 metabolic cages and their water balance and urine osmolality were examined.

63 3 have impairment in their water balance and urine osmolality, which correlates with the downregulati

64 how the association between water intake and urine osmolality, which is a hydration biomarker, varied