ライフサイエンスコーパス: use

1 s and biologics that could be of therapeutic use.

2 en different dearomatized pincer ligands are used.

3 vity, oropharynx, larynx, or nasopharynx was used.

4 r catastrophic payment incidence measure was used.

5 h referred to as "trimethylation enhancement using (13)C-diazomethane" ((13)C-TrEnDi), which results

6 Using 19,257 papers published by participants, we recons

7 Women kept a diary of products that they used 24 h prior to and during the collection.

8 sly described hemocompatibility score, which uses 4 escalating tiers of hierarchal severity to derive

9 Using 5 nm detonation nanodiamond covalently linked to p

10 prostate cancer lesion visualization in men using (68)Ga-NeoBOMB1 and PET/CT is also presented.

11 In this paper, we use a high-throughput microfluidic platform as a quantit

12 e death of a virus-infected cell, poxviruses use a range of different molecular strategies including

13 For 2015 live births, we used a compartmental model to estimate (1) exposure to m

14 (mrc1a:egfp)(y251) transgenic zebrafish that uses a mannose receptor, C type 1 (mrc1a) promoter to dr

15 racture networks are quantitatively analyzed using a combination of 2-D slice analysis and 3-D visual

16 Using a combination of evolutionary analysis, reinforcem

17 ed since SCOP development concluded in 2009, using a combination of manual curation and highly precis

18 Using a conditional mouse genetic approach to disable no

19 nalyte, which we call "degenerate features", using a context-driven annotation approach.

20 of the fluoranthene monomers was carried out using a divergent strategy that allows for systematic st

21 vitation behavior was designed and validated using a dual-transducer system operating at the clinical

22 offspring in a functionally relevant context using a fully factorial design.

23 owcases a new catalytic cyclization reaction using a highly Lewis acidic borane with concomitant C-H

24 Using a malaria transmission model we demonstrate that i

25 e prediction of adult cardiovascular disease using a model comprised entirely of adult nonlaboratory-

26 d energetics of triple junctions in graphene using a multiscale modelling approach based on combining

27 Using a novel activity-dependent technology called CANE

28 The net burden of HRAE was also assessed by using a previously described hemocompatibility score, wh

29 ation to self-administer cocaine as measured using a progressive ratio reinforcement schedule and to

30 values of 205 small molecules and validated using a set of 131 pesticides.

31 Using a ternary mixture of lipids, the modulated-intensi

32 Using a translational approach, we then demonstrate that

33 Using a xenograft model, we found that 3-aminopyridine-2

34 s the outcome of liver-directed gene therapy using AAV vectors and showed in a proof-of-principle stu

35 acceptor (about 50%) and A3 (tat) the least used (about 3%).

36 found that A5 (env/nef) is the most commonly used acceptor (about 50%) and A3 (tat) the least used (a

37 ptive separation processes can be lowered by using adsorbents that discriminate molecules based on ad

38 ort a method to suppress streaming potential using an Ag-coated microfluidic channel on a p-type sili

39 We present a method, using an infrared laser, for reproducible heat-dependent

40 iction of transcription factor binding sites using an integrative energy function that combines a kno

41 these findings into preclinical applications using an RNA interference (RNAi)-based approach.

42 /serotonin-norepinephrine reuptake inhibitor use and 11 studies reported morbidity in patients using

43 The relative ease of use and abundant access to tCS may represent a broad-rea

44 ut there have been few studies on antibiotic use and allergic disease.

45 search is focused on the design of simple-to-use and cheaper biodevices, while improving their select

46 the associations between systemic medication use and intraocular pressure (IOP) in the general popula

47 icance of the association between dabigatran use and myocardial infarction varied in sensitivity anal

48 uoroquinolone (moxifloxacin or levofloxacin) use and patient mortality, adjusting for risk factors ty

49 arm of ARGs under Finnish limited antibiotic use and suggest that such practices could help reduce th

50 a challenge to treat patients with cirrhosis using anticoagulants, because of the perception that the

51 D8 T cells were expanded from healthy donors using artificial APCs.

52 ed to reduce emissions and to facilitate its use as fertilizer, but a systematic analysis of these te

53 This enzyme's potential for the use as the enzyme for blood glucose monitor enzyme senso

54 aptation of polar capsules to parasitism, we used as a model organism Ceratonova shasta, which causes

55 spray chamber, and a rotary injection valve, used as an online interface between the microextraction

56 Hyperpolarized (129)Xe and (3)He are gases used as contrast media for magnetic resonance imaging th

57 a protein can also be selectively increased using ASOs designed to hybridize to other translation in

58 Using Aspergillus nidulans, we show that AP-2 has a clat

59 Here using band shift assays, fluorescence Job plots, and yea

60 In a design using basic features of revealed preference theory, we m

61 Here we use biochemical and structural methods to show that two

62 deliver therapeutic compounds to neutrophils using biocompatible, nanometer-sized synthetic vesicles,

63 ntial to expand communication 'bandwidth' by using biomolecules and providing electrochemical access

64 c labeling of RNA can be profiled and imaged using bioorthogonal chemistry.

65 Continuous renal replacement therapy using blood flow rate set at 250 mL/min was not more lik

66 atabase of binding sites have been evaluated using both a distance and a volumetric overlap approach.

67 absence and disability pension levels can be used by patients when planning their work, by health car

68 Given an enormous variety of strategies used by phages to overcome their hosts, one can expect t

69 d largely unknown what neural mechanisms are used by the primate auditory cortex to extract these bio

70 Heavy alcohol use can lead to progressive liver damage, especially in

71 -chosen molecular descriptors, was optimized using CCS values of 205 small molecules and validated us

72 Here, we used chimeric proteins to test whether DAT and SERT N an

73 Here, by combining studies using chromatin immunoprecipitation with sequencing and

74 We used chronoamperometry to measure protease-digested GA s

75 gastric bacterial infection in a mouse model using clarithromycin as a model antibiotic and Helicobac

76 We then used cluster analysis to identify patterns of individual

77 Results were compared using Cohen's kappa and linear regression, respectively.

78 Using commercial laboratory data, we found 80% of 29382

79 Using computational analysis, we describe the structural

80 evisiae was genetically shown in C. albicans using conditional TOR1 alleles.

81 Using confocal and electron microscopy as well as mathem

82 By using conformal oblique incidence thin film deposition o

83 Plants use context-dependent information to calibrate growth re

84 onsteroidal anti-inflammatory drugs (NSAIDs) use could trigger acute myocardial infarction (AMI).

85 We used Cox proportional hazards regression models to asses

86 Risk of bias was assessed using criteria from the Cochrane Collaboration.

87 We tested this model using cued recall tasks, in which subjects had to memori

88 Using cytometry by time-of-flight, we were able to ident

89 We conducted a population-based cohort study using Danish national registers.

90 To use data from the Pediatric Contact Dermatitis Registry

91 Mini Mental State Examination [MMSE] </=25) using data from nine cohorts of patients with Parkinson'

92 ency range and the wide bipolar bias regions using Debye-Frohlich model (combined with the Zhang form

93 Among patients with cirrhosis, statin use decreased the risk of decompensation, mortality, and

94 r selected primary healthcare (PHC) services using dedicated mobile teams and volunteer community mob

95 to drug therapy, a resurgence of interest in using diet to manage and treat DM has emerged in recent

96 We used diffusion MR imaging data and the Tract-Based Spati

97 t 30 days of life, while diagnoses of opioid use disorder during this period were uncommon in both gr

98 adverse health outcomes, including substance use disorders.

99 peratures during flowering and grain filling using donors such as NL-44, will minimize the negative i

100 We used Drosophila melanogaster and Saccharomyces cerevisia

101 nute spin, 100% of samples were undetectable using either assay, showing full concordance with the Ta

102 Despite recent progress in imaging defects using electron and X-ray techniques, in situ three-dimen

103 r putative periodontitis-associated variants using existing GWAS data from a German case-control samp

104 + CD25 + FOXP3 + CD127dim/-) were evaluated using flow cytometry in 32 patients with cGvHD treated b

105 in-fixed sections of the lungs were analyzed using fluorescence imaging, autoradiography, and immunoh

106 Using fluorescence microscopy and cryo-electron tomograp

107 This will be of potential use for monitoring HD mouse model disease progression an

108 nditions and risk factors associated with ED use for nonurgent and urgent ocular problems.

109 but only the final cell counts are commonly used for clinical decisions.

110 ce XANES spectra, allowing this method to be used for fingerprinting and linear combination analysis

111 odification at defined positions that can be used for in vitro studies is highly desirable.

112 ir basic electrochemical characteristics and used for in vivo measurements of oxygen with high resolu

113 g solar energy, presents trade-offs for land used for the production of food and the conservation of

114 flexor digitorum longus tendon is frequently used for the treatment of posterior tibial tendon insuff

115 Here, we show using functional GFP reconstitution experiments that Ken

116 r subtypes of glioblastoma (GBM) are defined using gene expression and mutation profiles, we identify

117 Cases were identified using glaucoma surgical codes for trabeculectomy, compli

118 myeloma (MM) patients and normal individuals using global reasoning on the RN causality to identify k

119 with no history of skin disease was analysed using high-throughput proteomic analysis that detects ex

120 atment, and rationalising isolation facility use; however, insufficient evidence exists to support it

121 Here, we used human intracranial recordings and visual word-by-wo

122 subjects) was sequenced for the V1-V3 region using Illumina's 2 x 300 bp chemistry.

123 migration and invasion compared to commonly used, immortalized TB cell lines and primary cells from

124 says, enhancing its applicability for direct use in CITES enforcement for distinguishing it from H. i

125 othelial protection supporting its potential use in the treatment of vascular cognitive impairment.

126 ses from waste rich in antimony, a component used in batteries, electronics, ammunitions, plastics, a

127 O-8 aimed to verify this hypothesis commonly used in clinical practice although it has not been prosp

128 (e.g., the Huntington disease), and thus was used in genetic testing for screening individuals at hig

129 e pneumococcal conjugate vaccines (PCVs) are used in national immunization programs in many developin

130 The model used in the study is an adaptation of the FutureDocs phy

131 y distributed in china, has been extensively used in traditional Chinese medicine.

132 Here, using in situ electron microscopy, we show how gold and

133 will optimize the extracted biological data using in vitro-in vivo correlations.

134 rrent hookah use) to 58.3% (ever e-cigarette use), indicating substantial false-negative rates.

135 ld tap water and urine samples were measured using inductively coupled mass spectrometry (ICP-MS) and

136 id layer containing docetaxel and clinically used inhibitor of sphingosine kinase 1 (SK1) FTY720 (fin

137 The SPR signal processing using integration area under the reflectivity curve is a

138 In this study, we use Intergovernmental Panel on Climate Change (IPCC) Tie

139 and its diagnostic performance was assessed using internal and external validation cohorts and compa

140 of the kinematics that were being generated using intracortical recordings from two people with tetr

141 tis C (HCV); however, the impact of nonheavy use is not clear.

142 reatic alpha amylase (PPAA) was investigated using isolated starch and cooked potato tuber as substra

143 A total of 1225 users used it more than once, during the evaluated period.

144 but are difficult to identify unambiguously using linear optical spectroscopy methods.

145 Using lipid nanoparticle formulations of these enhanced

146 We used log-linear and nonlinear concentration-response coe

147 anomalous Hall effect has been investigated using low-frequency transport measurements.

148 te decarboxylase (MDC), which allows them to use malonate as the sole carbon source.

149 Using mass spectrometry analysis, we found that VLVs con

150 e, m-xylene, o-xylene (BTEX), and total BTEX using measurement based estimates of annual means at 179

151 comparable controls aged > 65 years in 2009 using Medicare claims data.

152 After clinical deterioration using meropenem monotherapy, treatment success was achie

153 nd accurate multiplex miRNA profiling method using modified isothermal EXPAR combined with high-resol

154 he cell cycle dependence of bacterial growth using multigenerational cell growth and shape data for s

155 Using multiple labeling approaches to identify pathways

156 We used multivariate analyses to evaluate clinicopathologic

157 We used multivariate logistic regression with PCR-confirmed

158 for E. coli quantification in water samples using nanomaterial modified assay.

159 equilibrium affinity constant was determined using native MS, revealing a nearly eightfold enhancemen

160 Thus, use of 2D membrane based off surface matrix may present

161 , the presence of a patient or colleague and use of a computer or telephone during each activity was

162 inhibition by either nutrient starvation or use of an active site inhibitor reduces Skp2 levels and

163 in samples with moderate matrix content, the use of an optimum internal standard (OIS) at a concentra

164 We compared changes over time in the use of assisted ventilation and oxygen therapy during th

165 The use of Cs2CO3 as base is critical.

166 the potential alterations resulting from the use of different monounsaturated-rich oils.

167 guidelines give a class I recommendation to use of embolic protection devices (EPD) for saphenous ve

168 Increasing use of emergency departments among older patients with p

169 One approach has been to make use of frustrated growth of the supramolecular assembly

170 cal outcomes (major adverse cardiac events), use of healthcare resources, and impact on health status

171 t the beginning of the learning curve of the use of imatinib, in a large population of patients with

172 Use of leaves of some species with prunasin, tyramine an

173 on of biomass into electricity, based on the use of metabolic activity of bacteria.

174 mal sample preparation method, including the use of methanol at a 3:1 ratio of solvent to milk for pr

175 he strong association was independent of the use of modern systemic chemotherapy and remained in prop

176 The use of multiple regression analysis demonstrates that FA

177 loride as a model system, we demonstrate the use of NMR to distinguish between free and bound polymer

178 The use of opportunistic computed tomography (CT) scans to a

179 flexibility for decisions about when to stop use of OPV in the context of uncertainty about whether o

180 From 2006 to 2012 the use of PC in ESLD patients increased substantially; soci

181 year) were more likely to report never/rare use of protective clothing (adjusted prevalence ratio [a

182 Detection was dramatically improved by use of real-time immuno-polymerase chain reaction (PCR),

183 protein polymerizations often relies on the use of supramolecular interactions and the organization

184 ores at 4-5 y of age were estimated with the use of the McCarthy Scales of Children's Abilities.

185 Our findings support the use of the SOFA and qSOFA classifications to identify pa

186 Use of this end point may expedite therapeutic developme

187 ides or sulfonates as alkylating agents, the use of unactivated olefins for alkylations has become at

188 By making use of usual interruptions of preoperative posturing we

189 synthetic samples allows planning potential uses of this energy to power different sensors and analy

190 However, using one of these devices alone, some common and harmle

191 , duration of abnormal peak flow, antibiotic use, or nonserious adverse events.

192 Using order-disorder kinetics as a generic example, we c

193 igand with a half-life suitable for clinical use outside of the research setting.

194 insufficient evidence exists to support its use over standard clinical care.

195 Here, we focus on a imidazolium based IL and use particle-probe rheology to (i) catch this phenomenon

196 PET data were analyzed using plasma and reference tissue-based methods to estim

197 R) of 22 healthy recreationally active males using positron emission tomography (PET) and the MOR-sel

198 The method we introduce uses precast gelatin-based molds in which a whole mouse

199 programming of peptidoglycan biosynthesis to use precursors terminating in D-Ala-D-Lac in place of D-

200 Using prion permissive cells, we determined how impairme

201 To answer this question, we used psychoacoustic tests and comparative analyses to in

202 -phosphocholine (DPPC) phospholipid mixtures using quartz crystal microbalance-based nanoviscosity me

203 MRI sedations performed over a 5-year period using records of patients' biodata, MRI date, indication

204 X-ray absorption fine structure (EXAFS) data using reference organic ligands demonstrated that Fe(II)

205 Here we use resting-state fMRI data from 176 subjects to show th

206 The shape of this relationship was examined using restricted cubic splines.

207 IgE-immunoblotting was also conducted using sera from children with wheat allergy.

208 the classification was evaluated and ranked using several classification quality metrics.

209 d-phase organic compounds in SOA is measured using several complementary techniques including aerosol

210 ical care by reducing unnecessary antibiotic use, shortening length of hospital stay, improving influ

211 100%; complete response rate, 58%), but its use should be reserved for patients with truly severe an

212 ed an in situ gelling rectal delivery system using silk-elastinlike protein polymers (SELPs).

213 for the fabrication of paper electrode (PE) using silver nanoparticles capped with octylamine (AgNPs

214 r of labeled training samples, we propose to use simulated RNA-seq datasets to train our model.

215 these receptors distinguish ACh and Cho, we used single-channel electrophysiology to measure resting

216 olorectal tumors and their microenvironments using single-cell RNA-seq from 11 primary colorectal tum

217 Using siRNAs to type I and II BMP receptors and the sign

218 e tried to incorporate the reported pathways used so far for modification of 2-D graphene sheets to m

219 le particle spectral broadening, as observed using spectral hole burning measurements.

220 Using this framework we compare a widely used state-of-the-art reference-based algorithm (called

221 We used steady-state oxic and anoxic chemostat cultures to

222 elta K analysis and visualization of results using STRUCTURE HARVESTER.

223 ron transfer and in situ production of HO(*) using structure-activity relationships.

224 d planar ultra-thin ThermoPhotoVoltaic cells using surface-plasmon-polariton thermal emitters, that t

225 ype 1 (HSV-1), which has a large DNA genome, using synthetic genomics tools.

226 To address this question, we used the Atonal family of proneural transcription factor

227 ll tumors were treated in a single procedure using the 4C or Perfexion Gamma Knife.

228 Calculations using the B3LYP, CASPT2, and CCSD(T) methods all predict

229 By using the C35S mutant of TRX, which formed a metastable

230 ucture (3D) model of Ss-RIOK-2 was generated using the Chaetomium thermophilum RIOK-2 protein kinase

231 Using the continuously growing mouse incisor as a model

232 few Zika NS1-binding ssDNA aptamers selected using the conventional SELEX protocol, and their applica

233 Using the detailed information about the molecular inter

234 Using the Global Burden of Disease study data and method

235 Using the lab strain NL4-3, we found that A5 (env/nef) i

236 od for identification of Leptospermum honeys using the MM1 fluorescence marker.

237 gative OPSCC in 2010 to 2012 were identified using the National Cancer Data Base, which includes more

238 The confirmatory analysis using the per-protocol sample (n = 153) failed to show n

239 zed by TEM, XRD, FTIR, XPS, TGA, BET, and CV using the redox couples [Fe(CN)6](-3/-4) and [Ru(NH3)6](

240 m for accurate and early diagnosis of CJD by using the RT-QuIC assay on CSF samples, OM samples, or b

241 tive [EGFR+] vs. EGFR-negative) was assessed using the Wilcoxon rank-sum test.

242 Using the Xenopus system, we show that RARbeta2 plays a

243 produce the 16-membered tylosin macrocycle, using them as biocatalysts in the chemoenzymatic synthes

244 ts of nutrient limitation within a mutualism using theoretical and experimental approaches with a syn

245 uddling therefore presents an opportunity to use thermodynamic theory to study an emergent adaptive a

246 Using these genes, we constructed a classifier for bacte

247 nd 11 studies reported morbidity in patients using these medications at admission to ICU.

248 Using this approach, an optimized macrocyclic peptide in

249 Using this combination, we examined an amyloid form of S

250 Using this framework we compare a widely used state-of-t

251 Using three mouse infection models, we show that the SIP

252 Clinical outcomes and health care use through 6 months were obtained from medical records

253 essed oligomerization respectively, which we use to tune the levels of Raf/MEK/ERK signaling.

254 of complex particles, and the latter can be used to assemble such particles into bulk materials.

255 piratory Disease and Exacerbation Risk), was used to assess exposure, breathing problems, tiring easi

256 as the markers on the other chromosomes were used to calculate kinship matrix as polygenic background

257 is characteristic of D. hamiltonii could be used to design specific assays, enhancing its applicabil

258 A factorial MANCOVA was used to detect interactions between hormonal plasma leve

259 DNA hairpins with an engineered sequence is used to detect ligand binding as blocking events during

260 The unpaired t test and chi(2) analysis were used to determine significant differences.

261 Logistic regressions were used to determine the association of migration on CVD ri

262 and horseradish peroxidase (MP-Ab-HRP) were used to efficiently capture ERalpha from the sample solu

263 ndogenous mannosylated proteins, a principle used to endow insulin analogs with glucose responsivity.

264 Log-linear models were used to estimate prevalence ratios (PRs) of feeding patt

265 Photoluminescence (PL) was used to estimate the concentration of point defects in G

266 gression with empirical standard errors were used to estimate the continuous and categorical associat

267 ultivariable binomial regression models were used to evaluate the effects of oral health, general hea

268 M and TEM imaging, and the observations were used to guide the optimisation of the process.

269 er continuous flow-LVAD database (n=354) was used to identify patients with chest computed tomographi

270 Purposeful sampling was used to include patients of different gender, age, wound

271 Thus, ZVI may be used to increase biocathode CH4 production, assist in th

272 bsequent bony callus formation, and could be used to induce cartilaginous callus formation.

273 Each Acanthamoeba isolate was used to infect EpiCorneal cells, a 3-dimensional human c

274 These networks are increasingly used to inform strategies to prevent and control the spr

275 This broad set of ligand-bound poses is then used to investigate general properties of ligand binding

276 ht, photostable, nanometer particles broadly used to investigate single molecule dynamics in vitro.

277 potential (ERP) and behavioral measures were used to investigate the time course of error-related pro

278 ethynylene macrocycles with ODNs, which were used to mediate the assembly of gold nanoparticles.

279 omatography (GC x GC) retention times can be used to predict 26 relevant properties for nonpolar chem

280 moters of differentially expressed genes was used to reconstruct regulatory networks involved in diff

281 tilocus model and least angle regression was used to select the most potentially associated single-nu

282 phagosome formation, review basic mechanisms used to sense this curvature, and then summarize the exi

283 Mouse models of T. cruzi infection have been used to study heart damage in Chagas disease.

284 MARS was used to support patients with severe liver trauma (SLT),

285 are the efficacy and safety of 2 sclerosants used to treat reticular veins: 0.2% polidocanol diluted

286 standard," ranged from 38.1% (current hookah use) to 58.3% (ever e-cigarette use), indicating substan

287 d large number of interactive particles, and uses tools and concepts from density functional theory.

288 the TFs ORA47, RAP2.6L, MYB59, and ANAC055, using transcriptome profiling of overexpressors and muta

289 ., WPI+SPI, WPI+CN and SPI+CN, were produced using transglutaminase, and their in vitro IgE reactivit

290 One solution to this problem is to use two-photon microscopy to target fluorescently labele

291 Here, we used two-photon Ca(2+) imaging to study visual processin

292 Using unbiased proteomic profiling of over 100 different

293 Using UV-vis spectroscopy, we could measure the amount o

294 nodeficiency has developed, researchers have used vaccine responses as a tool to characterize the phe

295 ibility of controlling magnetic domain walls using voltages offers an energy efficient route to overc

296 human immunoglobulin G (IgG) were fabricated using well-defined full-length antibody-polymer conjugat

297 We used whole-genome sequencing and phylogenetic analysis t

298 s some of the more common analytical methods used with this data.

299 Competitive serial transplantation assays using Zfp521-deficient mice revealed that ZFP521 regulat

300 ogically and high-fat diet-induced ER stress using Zip14(-/-) (KO) mice, which exhibit impaired hepat